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Your search keyword '"Xuerong Qiu"' showing total 5 results
Start Over Author "Xuerong Qiu" Publication Type Academic Journals
5 results on '"Xuerong Qiu"'

1. Lipid management in ischaemic stroke or transient ischaemic attack in China: result from China National Stroke Registry III

Author

Xu Zhang, Yongjun Wang, Kangning Chen, Lianbo Gao, Ye Tian, Xu Chen, Yi Guo, Benyan Luo, Yan Wang, Jian Wu, Xiaohong Li, Yong-Jun Wang, Qiang Dong, Huisheng Chen, Wei Wang, Zhengqi Lu, Lijie Ren, Runqing Wang, Juan Feng, Zhangyong Xia, Hao Li, Lihua Wang, Qingwei Zhao, Hong Wang, Ting Wang, Jin Zhou, Xia Meng, Jun Wu, Qing Li, Shizheng Wu, Ping Zhang, Li-Ping Liu, Yue-song Pan, Yi-long Wang, Ming Yu, Guohua Chen, Zhimin Wang, Jianhua Li, Yi Wang, Yi Yang, Xinsheng Han, Songdi Wu, Yongming Chen, Liang Zhao, Qiang Ma, Xiaoying Zhang, Mei Zhang, Limin Wang, Hui Liang, Liping Wang, Jun Zhou, Jie Lin, Yu Geng, Ning Wang, Yun Xu, Jinsheng Zeng, Huijuan Wang, Xueli Cai, Jia Yin, Jun Xu, Feng Qiu, Jun Zhao, Baojun Wang, Hainan Zhang, Zi-Xiao Li, Xing-Quan Zhao, Mingzhi Zhao, Yingchun Wu, Junling Zhang, Xuerong Qiu, Zhongping An, Wenjun Xue, Lili Zhao, Hongyan Li, Junfeng Shi, Tao Gong, Qi Fang, Liyan Liu, Jianfeng Wang, Guang Huang, Chun Wang, Yuwu Zhao, Lei Sheng, Lei Xia, Yan Fang, Xiaoxiang Peng, Yanling Wang, Yangmei Chen, Deqin Geng, Jinfeng Liu, Weirong Li, Yuqing Wei, Yu-Yuan Xu, Jilai Li, Maolin He, Quping Ouyang, Fengchun Yu, Chenlong Wang, Jinli Zhang, Wenqing Wu, Yaoyu Yu, Meiyun Zhang, Junyan Liu, Wanying Shi, Baoquan Lu, Lijun Geng, Shujuan Wang, Ruifang Liu, Fengli Zhao, Xinping Liu, Xuebing Sun, Tianyuan Li, Youming Wang, Xinxia He, Weiqiang Yuan, Ronghua Dou, Lihai Liu, Haisong Du, Cunrui Wang, Xiaofei Chen, Fengyun Hu, Fanping He, Xingchen Wang, Hongjin Li, Mingzong Yan, Guiru Zhang, Yunlin Liu, Yuhui Han, Xianghong Meng, Hongtian Zhang, Congmin Ma, Gexia Liu, Wenxu Zheng, Haitao Chi, Hongbo Xiao, Lijun Xiao, Guozhong Li, Yulan Zhu, Yindong Yang, Xuhai Gong, Qunhui Liu, Shiping Gong, Hongbin Zhou, Haipeng Li, Yong You, Jinsheng Lin, Heqing Zhao, Aixia Zhuang, Kaifu Ke, Zhengxie Dong, Guiyun Cui, Liangqun Rong, Yi Wu, Weiguo Tang, Yanjiang Wang, Wenguang Bu, Xiaohua Cheng, Jifu Cai, Lvli Li, Jianping Niu, Liping Zhan, Runxiu Zhu, Yanhui Du, Yongxia Wen, Yongcai Qu, Yuncheng Wu, Jianren Liu, Qingke Bai, Chaoming He, Weiwen Qiu, Shufang Yao, Xuwen Sun, Ligong Gao, Xianglin Chen, Qiuyan Shi, Zhaochen Li, Tianbao Chen, SuYun Yang, Yazhou Han, Xinxiao Wu, Beihai Jiang, Lizhong Li, Weidong Lou, Weiming Lan, Aihu Zheng, Qifu Bai, Lifang Luan, Liqing Yan, Yanxia Wang, Xuerong Huang, Xiangting Chai, Yanshu Liu, Liangjun You, Hongqin Yang, Dongfang Li, Linying Gui, Aisheng Wu, Dengling Wang, Qinghua Zhang, Yunhong He, Ruiyou Guo, Jijun Teng, Ping Lou, Wei-Qi Chen, Meng-Xing Wang, Yu’an Zou, An’ding Xu, Yinzhou Wang Li Pan, Li’e Wu, Yanru Zhao Li Liu, and Xiaoqian Shen

Subjects
Medicine
Abstract

Objectives The aims of the study were to assess the management of low-density lipoprotein cholesterol (LDL-C) and the goal achievement, as well as to investigate the association between baseline LDL-C level, lipid-lowering treatment (LLT), and stroke recurrence in patients with ischaemic stroke or transient ischaemic attack (TIA).Design Our study was a post hoc analysis of the Third China National Stroke Registry (CNSR-III).Setting We derived data from the CNSR-III - a nationwide clinical registry of ischaemic stroke and TIA based on 201 participating hospitals in mainland China.Participants 15,166 patients were included in this study with demographic characteristics, etiology, imaging, and biological markers from August 2015 to March 2018.Primary and secondary outcome measures The primary outcome was a new stroke, LDL-C goal (LDL-C

Published
2023
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2. Prognosis and antiplatelet therapy of small single subcortical infarcts in penetrating artery territory: a post hoc analysis of the Third China National Stroke Registry

Author

Xu Zhang, Yongjun Wang, Kangning Chen, Lianbo Gao, Ye Tian, Xu Chen, Yi Guo, Benyan Luo, Yan Wang, Jian Wu, Xiaohong Li, An-Xin Wang, Yong-Jun Wang, Qiang Dong, Huisheng Chen, Wei Wang, Zhengqi Lu, Jing Jing, Lijie Ren, Runqing Wang, Juan Feng, Zhangyong Xia, Hao Li, Lihua Wang, Qingwei Zhao, Hong Wang, Ting Wang, Jin Zhou, Xia Meng, Jun Wu, Qing Li, Shizheng Wu, Ping Zhang, Li-Ping Liu, Yi-long Wang, Ming Yu, Guohua Chen, Zhimin Wang, Jianhua Li, Yi Wang, Yi Yang, Xinsheng Han, Songdi Wu, Yongming Chen, Liang Zhao, Qiang Ma, Xiaoying Zhang, Mei Zhang, Limin Wang, Hui Liang, Liping Wang, Jun Zhou, Jie Lin, Yu Geng, Ning Wang, Yun Xu, Jinsheng Zeng, Huijuan Wang, Xueli Cai, Jia Yin, Jun Xu, Feng Qiu, Jun Zhao, Baojun Wang, Hainan Zhang, Zi-Xiao Li, Xing-Quan Zhao, Mingzhi Zhao, Yingchun Wu, Junling Zhang, Xuerong Qiu, Zhongping An, Wenjun Xue, Lili Zhao, Hongyan Li, Junfeng Shi, Mingzhen Li, Tao Gong, Qi Fang, Liyan Liu, Jianfeng Wang, Guang Huang, Chun Wang, Yuwu Zhao, Lei Sheng, Lei Xia, Yan Fang, Xiaoxiang Peng, Yanling Wang, Yangmei Chen, Deqin Geng, Jinfeng Liu, Weirong Li, Yuqing Wei, Yu-Yuan Xu, Yi-Jun Zhang, Jilai Li, Maolin He, Quping Ouyang, Fengchun Yu, Chenlong Wang, Jinli Zhang, Wenqing Wu, Yaoyu Yu, Meiyun Zhang, Junyan Liu, Wanying Shi, Baoquan Lu, Lijun Geng, Shujuan Wang, Ruifang Liu, Fengli Zhao, Xinping Liu, Xuebing Sun, Tianyuan Li, Youming Wang, Xinxia He, Weiqiang Yuan, Ronghua Dou, Lihai Liu, Haisong Du, Cunrui Wang, Yu'an Zou, Xiaofei Chen, Fengyun Hu, Fanping He, Xingchen Wang, Hongjin Li, Mingzong Yan, Guiru Zhang, Yunlin Liu, Yuhui Han, Xianghong Meng, Hongtian Zhang, Congmin Ma, Gexia Liu, Wenxu Zheng, Haitao Chi, Hongbo Xiao, Lijun Xiao, Guozhong Li, Yulan Zhu, Yindong Yang, Xuhai Gong, Qunhui Liu, Shiping Gong, Hongbin Zhou, Haipeng Li, Yong You, Jinsheng Lin, Heqing Zhao, Aixia Zhuang, Kaifu Ke, Zhengxie Dong, Guiyun Cui, Liangqun Rong, Yi Wu, Weiguo Tang, Yanjiang Wang, Wenguang Bu, Xiaohua Cheng, An'ding Xu, Jifu Cai, Lvli Li, Li Pan; Yinzhou Wang, Jianping Niu, Liping Zhan, Li'e Wu, Li Liu; Yanru Zhao, Runxiu Zhu, Yanhui Du, Yongxia Wen, Yongcai Qu, Yuncheng Wu, Jianren Liu, Qingke Bai, Chaoming He, Weiwen Qiu, Shufang Yao, Xuwen Sun, Ligong Gao, Xianglin Chen, Qiuyan Shi, Zhaochen Li, Tianbao Chen, SuYun Yang, Yazhou Han, Xinxiao Wu, Beihai Jiang, Lizhong Li, Weidong Lou, Weiming Lan, Aihu Zheng, Qifu Bai, Lifang Luan, Liqing Yan, Yanxia Wang, Xuerong Huang, Xiangting Chai, Yanshu Liu, Liangjun You, Hongqin Yang, Dongfang Li, Linying Gui, Aisheng Wu, Jianling Zhang, Dengling Wang, Qinghua Zhang, Yunhong He, Ruiyou Guo, Jijun Teng, and Ping Lou

Subjects
Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
Abstract

Background Small single subcortical infarction (SSSI) may be classified as parent artery disease-related or only branch involved according to the stenosis of parent artery. The study aimed to evaluate short-term and long-term prognoses and the effectiveness of antiplatelet therapy in SSSI.Methods We prospectively enrolled 2890 patients with SSSI from the Third China National Stroke Registry (CNSR-III) database from August 2015 to March 2018. We assessed clinical outcomes and antiplatelet treatment effects in patients with SSSI with and without parent artery stenosis (PAS) identified by magnetic resonance angiography.Results Among 2890 patients with SSSI in the perforator territory of the middle cerebral artery and the basilar artery, there were 680 (23.53%) patients with PAS and 2210 (76.47%) patients without PAS, respectively. After adjusting for potential confounders, the PAS group had a greater initial stroke severity (OR 1.262, 95% CI 1.058 to 1.505; p=0.0097) and a higher risk of ischaemic stroke recurrence at 3 months (OR 2.266, 95% CI 1.631 to 3.149; p

Published
2022
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3. Whole genome sequencing of 10K patients with acute ischaemic stroke or transient ischaemic attack: design, methods and baseline patient characteristics

Author

Yongjun Wang, Yilong Wang, Yang Liu, Hao Li, Zhe Xu, Xia Meng, Jun Wu, Anxin Wang, Yong Jiang, Guohua Chen, Zhimin Wang, Jinxi Lin, Songdi Wu, Zhengchang Jia, Yongming Chen, Yu Geng, Si Cheng, Xinying Huang, Xuerong Qiu, Binbin Song, Weizhong Ji, Zhongping An, Wenjun Xue, Lili Zhao, and Hongyan Li

Subjects
Neurology. Diseases of the nervous system, RC346-429
Abstract

Background and purpose Stroke is the second leading cause of death worldwide and the leading cause of mortality and long-term disability in China, but its underlying risk genes and pathways are far from being comprehensively understood. We here describe the design and methods of whole genome sequencing (WGS) for 10 914 patients with acute ischaemic stroke or transient ischaemic attack from the Third China National Stroke Registry (CNSR-III).Methods Baseline clinical characteristics of the included patients in this study were reported. DNA was extracted from white blood cells of participants. Libraries are constructed using qualified DNA, and WGS is conducted on BGISEQ-500 platform. The average depth is intended to be greater than 30× for each subject. Afterwards, Sentieon software is applied to process the sequencing data under the Genome Analysis Toolkit best practice guidance to call genotypes of single nucleotide variants (SNVs) and insertion-deletions. For each included subject, 21 fingerprint SNVs are genotyped by MassARRAY assays to verify that DNA sample and sequencing data originate from the same individual. The copy number variations and structural variations are also called for each patient. All of the genetic variants are annotated and predicted by bioinformatics software or by reviewing public databases.Results The average age of the included 10 914 patients was 62.2±11.3 years, and 31.4% patients were women. Most of the baseline clinical characteristics of the 10 914 and the excluded patients were balanced.Conclusions The WGS data together with abundant clinical and imaging data of CNSR-III could provide opportunity to elucidate the molecular mechanisms and discover novel therapeutic targets for stroke.

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4. Discriminating poststroke depression from stroke by nuclear magnetic resonance spectroscopy-based metabonomic analysis.

Author

Jianqi Xiao, Jie Zhang, Dan Sun, Lin Wang, Lijun Yu, Hongjing Wu, Dan Wang, and Xuerong Qiu

Subjects
STROKE patients, STROKE, MENTAL depression, MENTAL health, METABOLITES, PSYCHOLOGY
Abstract

Poststroke depression (PSD), the most common psychiatric disease that stroke survivors face, is estimated to affect ~30% of poststroke patients. However, there are still no objective methods to diagnose PSD. In this study, to explore the differential metabolites in the urine of PSD subjects and to identify a potential biomarker panel for PSD diagnosis, the nuclear magnetic resonance-based metabonomic method was applied. Ten differential metabolites responsible for discriminating PSD subjects from healthy control (HC) and stroke subjects were found, and five of these metabolites were identified as potential biomarkers (lac- tate, a-hydroxybutyrate, phenylalanine, formate, and arabinitol). The panel consisting of these five metabolites provided excellent performance in discriminating PSD subjects from HC and stroke subjects, achieving an area under the receiver operating characteristic curve of 0.946 in the training set (43 HC, 45 stroke, and 62 PSD subjects). Moreover, this panel could classify the blinded samples from the test set (31 HC, 33 stroke, and 32 PSD subjects) with an area under the curve of 0.946. These results laid a foundation for the future development of urine-based objective methods for PSD diagnosis and investigation of PSD pathogenesis. [ABSTRACT FROM AUTHOR]

Published
2016
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