113 results on '"Yakushiji, Fumika"'
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2. Synthesis and biological evaluation of echinomycin analogues as potential colon cancer agent
3. Click strategy using disodium salts of amino acids improves the water solubility of plinabulin and KPU-300
4. Beneficial effects of a new neuroprotective compound in neuronal cells and MPTP-administered mouse model of Parkinson's disease.
5. Solid-Phase Synthesis of Nannocystin Ax and Its Analogues.
6. Development of potent dipeptide-type SARS-CoV 3CL protease inhibitors with novel P3 scaffolds: Design, synthesis, biological evaluation, and docking studies
7. Design, synthesis, and biological evaluation of novel dipeptide-type SARS-CoV 3CL protease inhibitors: Structure–activity relationship study
8. Design and synthesis of new tripeptide-type SARS-CoV 3CL protease inhibitors containing an electrophilic arylketone moiety
9. Synthesis and structure–activity relationships of benzophenone-bearing diketopiperazine-type anti-microtubule agents
10. Tubulin photoaffinity labeling study with a plinabulin chemical probe possessing a biotin tag at the oxazole
11. Solid-phase synthesis of fluorescent analogues of Park’s nucleotide, lipid I and lipid II
12. Anti-microtubule ‘plinabulin’ chemical probe KPU-244-B3 labeled both α- and β-tubulin
13. Structure, solubility, and permeability relationships in a diverse middle molecule library
14. Synthetic Modifications of Histones and Their Functional Evaluation.
15. Development of cyclic peptide derivatives from the N-terminal region of LANA for targeting the nucleosome acidic patch
16. Study of the structure-activity relationship of polymyxin analogues
17. Recent Advances in Iridoid Chemistry: Biosynthesis and Chemical Synthesis.
18. Elucidating the Structural Requirement of Uridylpeptide Antibiotics for Antibacterial Activity.
19. Total Synthesis of Acaulide and Acaulone A.
20. Synthesis and biological evaluation of a MraY selective analogue of tunicamycins.
21. Polycomb Repressive Complex 2: Modulator Development for Functional Regulation of a Multiprotein Complex by Using Structural Information.
22. Palladium-catalyzed C3-selective mono-arylation of 4-hydroxycoumarin
23. Total Synthesis of Plusbacin A3 and Its Dideoxy Derivative Using a Solvent-Dependent Diastereodivergent Joullié–Ugi Three-Component Reaction.
24. Development of a solid-supported biotinylation reagent for efficient biotin labeling of SH groups on small molecules
25. HIV-1 susceptibility of transgenic rat-derived primary macrophage/T cells and a T cell line that express human receptors, CyclinT1 and CRM1 genes.
26. Identification of a degrading enzyme in human serum that hydrolyzes a C-terminal core sequence of neuromedin U.
27. Diastereoselective construction of substituted tetrahydropyrans using an intramolecular oxy-Michael strategy
28. Effect of N-Terminal Acylation on the Activity of Myostatin Inhibitory Peptides.
29. Development of the Thiol-Selective Solid-Supported Oligoarginine-Conjugating Reagent KSH-2.
30. 3-Nitro-2-pyridinesulfenyl-mediated solid-phase disulfide ligation in the synthesis of disulfide bond-containing cyclic peptides.
31. Identification of the MinimumPeptide from Mouse MyostatinProdomain for Human Myostatin Inhibition.
32. Discovery of Natural Products Possessing Selective Eukaryotic Readthrough Activity: 3- epi-Deoxynegamycin and Its Leucine Adduct.
33. Discovery of Selective HexapeptideAgonists to HumanNeuromedin U Receptors Types 1 and 2.
34. Synthesis and Structure–Activity Relationship Study of Antimicrotubule Agents Phenylahistin Derivatives with a Didehydropiperazine-2,5-dione Structure.
35. Water-Soluble Prodrug of Antimicrotubule Agent Plinabulin: Effective Strategy with Click Chemistry.
36. ChemInform Abstract: Palladium-Catalyzed C3-Selective Mono-Arylation of 4-Hydroxycoumarin.
37. ChemInform Abstract: Medicinal Chemistry and Chemical Biology of Diketopiperazine-Type Antimicrotubule and Vascular-Disrupting Agents.
38. Total Synthesis of (+)-Lasonolide A.
39. Enantioselective Construction of the C1-C16 Segment of Lasonolide A.
40. Total synthesis of (+)-negamycin and its 5-epi-derivative
41. Concise Synthesis of 11-Noriridoids via Pauson-Khand Reaction.
42. [Development of Novel Biologically Active Compounds Based on Synthetic Organic Chemistry].
43. Total Synthesis of Echinomycin and Its Analogues.
44. [Diversity-oriented Symposium: Diversity Experiences through Study Abroad].
45. Total Synthesis of Plusbacin A 3 and Its Dideoxy Derivative Using a Solvent-Dependent Diastereodivergent Joullié-Ugi Three-Component Reaction.
46. Total Synthesis of Tunicamycin V.
47. Solid-Phase Modular Synthesis of Park Nucleotide and Lipids I and II Analogues.
48. Total Synthesis and Antibacterial Investigation of Plusbacin A 3 .
49. Novel Hybrid Compound of a Plinabulin Prodrug with an IgG Binding Peptide for Generating a Tumor Selective Noncovalent-Type Antibody-Drug Conjugate.
50. Structure-Activity Relationship Studies of 3-epi-Deoxynegamycin Derivatives as Potent Readthrough Drug Candidates.
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