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In 2022, the National Cancer Center released the latest data. The results show that the incidence of gynecologic tumors in China shows an upward trend. Taking ovarian cancer as an example, the annual number of new cases is 57 200, with a crude incidence rate of 8.47/100 000, and the annual number of death cases is 27 200, with a crude mortality rate of 4.04/100 000, and the morbidity and mortality are higher than the world standard rates (5.59/100 000 and 2.45/100 000, respectively). Physicians practicing gynecologic oncology in China face greater challenges. Patients with early gynecologic tumors have better overall outcomes after standardized treatment. However, limited treatment modalities and high recurrence rates often lead to poorer prognosis for patients with advanced, recurrent or metastatic gynecologic malignancies. In recent years, emerging treatments such as targeted therapy, immunotherapy and antibody-drug conjugate have ushered in a new era in the treatment of gynecologic tumors, bringing more hope to patients. This article summarized the significant advances in gynecological tumor surgery, radiotherapy, chemotherapy, targeted therapy, immunotherapy and biomarkers in the past year, so as to better guide the individualized and precise treatment of gynecologic tumors.

Since Jia Zhangke's direction of the first long movie "Xiao Wu", his works has won many great prizes at each international film festival. It has much to do with his persisting the realism style in creation. He is always sober-minded and makes full use of the camera lens, paying attention to the destiny of the people at a borderline, describing the story occurs in real world. This article deeply analyzes the connotation that the abstract narrative space of his movie "World" tries to reveal. It pointes out that under the "grassroots complex" and the "nostalgia", people get lost while seeking for social attribution and themselves, thus creating certain reaction force leading the fault of the society. [ABSTRACT FROM AUTHOR]

The inclusions in large diamond single crystals have effects on its ultimate performance, which restricts its industrial applications to a great extent. Therefore, it is necessary to study the inclusions systematically. In this paper, large diamond single crystals with different content values of inclusions are synthesized along the (100) surface by the temperature gradient method (TGM) under 5.6 GPa at different temperatures. With the synthetic temperature changing from 1200 °C to 1270 °C, the shapes of diamonds change from plate to low tower, to high tower, even to steeple. From the microscopic photographs of the diamond samples, it can be observed that with the shapes of the samples changing at different temperatures, the content values of inclusions in diamonds become zero, a little, much and most, correspondingly. Consequently, with the temperature growing from low to high, the content values of inclusions in crystals increase. The origin of inclusions is explained by the difference in growth rate between diamond crystal and its surface. The content values of inclusions in diamond samples are quantitatively calculated by testing the densities of diamond samples. And the composition and inclusion content are analyzed by energy dispersive spectroscopy (EDS) and x-ray diffraction (XRD). From contrasting scanning electron microscopy (SEM) photographs, it can be found that the more the inclusions in diamond, the more imperfect the diamond surface is. [ABSTRACT FROM AUTHOR]