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Your search keyword '"Zhang, Longzhen"' showing total 247 results
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247 results on '"Zhang, Longzhen"'

4. Banach–Mazur Distance from \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\ell_p^3$$\end{document} \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\ell_\infty^3$$\end{document} to \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\ell_p^3$$\end{document} \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\ell_\infty^3$$\end{document}

Author

Zhang, Longzhen, Meng, Lingxu, and Wu, Senlin

Published
2023
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6. Results of the phase IIa study to evaluate the efficacy and safety of rezivertinib (BPI-7711) for the first-line treatment of locally advanced or metastatic/recurrent NSCLC patients with EGFR mutation from a phase I/IIa study

Author

Shi, Yuankai, Zhou, Jianying, Zhao, Yanqiu, Zhu, Bo, Zhang, Liangming, Li, Xingya, Fang, Jian, Shi, Jianhua, Zhuang, Zhixiang, Yang, Sheng, Wang, Donglin, Yu, Huiqing, Zhang, Longzhen, Zheng, Rongsheng, Greco, Michael, and Wang, Tingting

Published
2023
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11. Central nervous system efficacy of rezivertinib (BPI-7711) in advanced NSCLC patients with EGFR T790M mutation: A pooled analysis of two clinical studies

Author

Yang, Sheng, Wu, Shiman, Zhao, Yanqiu, Chen, Gongyan, Zhu, Bo, Li, Xingya, Wang, Ke, Shi, Jianhua, Cang, Shundong, Yao, Wenxiu, Fan, Yun, Fang, Jian, Zhang, Liangming, Zhou, Jianying, Wu, Lin, Zheng, Rongsheng, Huang, Meijuan, Pan, Yueyin, Yang, Zhixiong, Sun, Meili, Yu, Huiqing, Wang, Donglin, Huang, Jianan, Wang, Lijun, Shu, Yongqian, Chen, Zhaohong, Liu, Chunling, Li, Jingzhang, Liu, Jiwei, Sun, Shenghua, Guo, Yanzhen, Meng, Zili, Liu, Zhefeng, Han, Zhigang, Wu, Gang, Lu, Hong, Ma, Rui, Hu, Sheng, Zhao, Guofang, Zhang, Longzhen, Liu, Zheng, Xie, Congying, Zhong, Diansheng, Zhao, Hui, Bi, Minghong, Yi, Shanyong, Guo, Shuliang, Yi, Tienan, Li, Wen, Lin, Yingcheng, Chen, Zhendong, Zhuang, Zhixiang, Guo, Zhongliang, Greco, Michael, Wang, Tingting, Zhou, Anqi, and Shi, Yuankai

Published
2023
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13. Efficacy and Safety of Rezivertinib (BPI-7711) in Patients With Locally Advanced or Metastatic/Recurrent EGFR T790M-Mutated NSCLC: A Phase 2b Study

Author

Shi, Yuankai, Wu, Shiman, Wang, Ke, Cang, Shundong, Yao, Wenxiu, Fan, Yun, Wu, Lin, Huang, Meijuan, Li, Xingya, Pan, Yueyin, Yang, Zhixiong, Zhu, Bo, Chen, Gongyan, Shi, Jianhua, Sun, Meili, Fang, Jian, Wang, Lijun, Chen, Zhaohong, Liu, Chunling, Li, Jingzhang, Liu, Jiwei, Sun, Shenghua, Zhao, Yanqiu, Guo, Yanzhen, Meng, Zili, Liu, Zhefeng, Han, Zhigang, Lu, Hong, Ma, Rui, Hu, Sheng, Zhao, Guofang, Liu, Zheng, Xie, Congying, Zhong, Diansheng, Zhao, Hui, Yu, Huiqing, Zhang, Longzhen, Bi, Minghong, Yi, Shanyong, Guo, Shuliang, Yi, Tienan, Li, Wen, Lin, Yingcheng, Shu, Yongqian, Chen, Zhendong, Guo, Zhongliang, Greco, Michael, Wang, Tingting, and Shen, Haijiao

Published
2022
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14. PA2PbBr4/MAPbBr3 Heterojunction X‐Ray Detector with Enhanced Sensitivity and Excellent Self‐Powered Functionality.

Author

He, Ningfang, Zhang, Longzhen, He, Xin, Guo, Jiahao, Wu, Xiaochao, Li, Qingkui, and He, Jilin

Subjects
*DETECTORS, *HETEROJUNCTIONS, *X-ray detection, *ELECTRIC fields, *DETECTION limit
Abstract

Heterojunctions combining 2D and 3D perovskites have caused a surge in the research on X‐ray detectors. The enhanced charge transport facilitated by the built‐in electric field further amplifies the potential of this material system, paving the way for highly sensitive and efficient X‐ray detectors. In this study, PA2PbBr4 single‐crystal film with a thickness of 10 µm is successfully grown on the surface of MAPbBr3 substrate via liquid phase epitaxial method, forming a 2D/3D heterojunction. This innovative detector exhibits a dramatically enhanced sensitivity of 3.81 × 104 µC Gy−1 cm−2 at an X‐ray tube voltage of 70 keV and a bias of 50 V mm−1, along with an ultra‐low detection limit of 11.84 nGy s−1, surpassing the performance of the conventional MAPbBr3 X‐ray detectors by a factor of four and 2 × 103 times higher than that of commercialized α‐Se detectors. Furthermore, the 2D/3D heterojunction exhibits exceptional self‐powered X‐ray detection capabilities, achieving a remarkable sensitivity of 3562.26 µC Gy−1 cm−2 at 70 keV X‐ray tube voltage. This superior performance implies reduced energy consumption, high portability, decreased ion migration, and provides inspiration for the next generation of high‐performance X‐ray detectors. [ABSTRACT FROM AUTHOR]

Published
2024
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15. FTO blocks RNA translational activity via the loss of N6‐methyladenosine methylation at 5′ UTR regulated by RBM5 in cisplatin‐resistant NSCLC.

Author

Li, Liantao, Qu, Debao, Wang, Bo, Yuan, Shiwang, Zhao, Yang, Liu, Nianli, Huo, Fuchun, Zhang, Dan, and Zhang, Longzhen

Subjects
RNA-binding proteins, GENE silencing, GENETIC translation, LUNG cancer, NON-small-cell lung carcinoma
Abstract

N6‐methyladenosine (m6A) methylation has been widely regarded in numerous biological functions including CR. Nonetheless, the molecular process of m6A methylation behind CR in non‐small cell lung cancer (NSCLC) has no apparent significance. We identified in this study that the expression of FTO alpha‐ketoglutarate dependent dioxygenase (FTO) was downregulated in CR NSCLC tissues and cells in vivo and in vitro. Additionally, RIP‐seq indicated that loss of FTO contributed to the elevated m6A methylation at 5′‐untranslated region of RNAs which were closely connected with tumor resistance and malignancy, and FTO exerted to exclude the recruitment of eIF3A to these target genes in CR NSCLC. Moreover, FTO‐enriched transcripts displayed a reduced translational capability in CR NSCLC compared to the regular NSCLC cells. Finally, we also identified RNA binding motif protein 5 (RBM5) that could specially interact with FTO in regular NSCLC compared to CR NSCLC. Deficiency of RBM5 resulted in the abnormal recognition of transcripts by FTO, and led to the translation silencing of genes associated with CR such as ATP7A, ERCC1, CD99, CDKN3, XRCC5, and NOL3. Taken together, our data characterized FTO as a novel translation regulator and revealed the molecular mechanism on gene translation through the synergistic effects with RBM5 and m6A methylation in CR NSCLC cells. [ABSTRACT FROM AUTHOR]

Published
2024
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16. Photocatalytic CO2 reduction enhanced by the thermochromic effect of modified VO2.

Author

Zhang, Longzhen, Xuan, Yimin, Wang, Qi, Zhu, Zhonghui, Zhao, Dawei, Liu, Xianglei, Zhu, Qibin, and Zhang, Kai

Abstract

Photocatalytic CO2 reduction to solar fuels holds great promise for storing renewable energy and mitigating global warming. However, its widespread application is hindered by the low optical absorption and inefficient utilization of charge carriers. One prospective approach to enhance photocatalytic performance involves converting low-energy photons into thermal energy. In this work, we explore the utilization of the thermochromic effect to enhance the selectivity and activity of photocatalytic CO2 conversion, particularly in scenarios without photosensitizers and sacrificial agents. We have combined Mo-doped VO2 (M1V), a thermochromic material, with an InVO4 (IV) photocatalyst to enhance optical absorption and facilitate charge transfer in IV. The M1V-IV composite exhibits exceptional selectivity in solar-driven CO2 reduction, an excellent selectivity of 99% with a photothermal CO formation rate of 58.4 μmol h−1 g−1 in pure water under 330 mW cm−2 light irradiation. The CO evolution rate for M1V-IV is 1.5 times higher than that of the VO2–InVO4 composite and 6 times higher than that of pure IV. Comprehensive spectroscopic characterization and theoretical calculations disclose that the enhanced performance is attributed to the increased separation of charge carriers and the photocatalytic enhancement of CO2 reduction due to the thermal effect. We successfully propose a reaction mechanism for CO2 photoreduction on M1V-IV. This work introduces a novel strategy to enhance photocatalytic performance by leveraging the thermochromic effect in CO2 reduction. [ABSTRACT FROM AUTHOR]

Published
2024
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22. Efficacy, Safety, and Population Pharmacokinetics of MW032 Compared With Denosumab for Solid Tumor–Related Bone Metastases: A Randomized, Double-Blind, Phase 3 Equivalence Trial.

Author

Zhang, Shaohua, Yin, Yongmei, Xiong, Hailin, Wang, Jingfen, Liu, Hu, Lu, Junguo, Zhang, Qingyuan, Zhang, Longzhen, Zhong, Jincai, Nie, Jianyun, Lei, Kaijian, Wang, Hong, Yang, Shu, Yao, Herui, Wu, Huijing, Yu, Ding, Ji, Xuening, Zhang, Hua, Wu, Fang, and Xie, Weimin

Published
2024
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28. An Algorithm Based on Compute Unified Device Architecture for Estimating Covering Functionals of Convex Bodies.

Author

Han, Xiangyang, Wu, Senlin, and Zhang, Longzhen

Subjects
FUNCTIONALS, OPTIMIZATION algorithms, DISCRETE geometry, CONVEX geometry, CONVEX bodies, GLOBAL optimization
Abstract

In Chuanming Zong's program to attack Hadwiger's covering conjecture, which is a longstanding open problem from Convex and Discrete Geometry, it is essential to estimate covering functionals of convex bodies effectively. Recently, He et al. and Yu et al. provided two deterministic global optimization algorithms having high computational complexity for this purpose. Since satisfactory estimations of covering functionals will be sufficient in Zong's program, we propose a stochastic global optimization algorithm based on CUDA and provide an error estimation for the algorithm. The accuracy of our algorithm is tested by comparing numerical and exact values of covering functionals of convex bodies including the Euclidean unit disc, the three-dimensional Euclidean unit ball, the regular tetrahedron, and the regular octahedron. We also present estimations of covering functionals for the regular dodecahedron and the regular icosahedron. [ABSTRACT FROM AUTHOR]

Published
2024
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34. Banach–Mazur Distance from to.

Author

Zhang, Longzhen, Meng, Lingxu, and Wu, Senlin

Subjects
BANACH spaces
Abstract

The maximum of the Banach–Mazur distance , where ranges over the set of all -dimensional real Banach spaces, is difficult to compute. In fact, it is even not easy to find the maximum of over all . We prove that for all . As an application, the following result related to Borsuk's partition problem in Banach spaces is obtained: any subset of having diameter is a union of subsets of whose diameters are at most . [ABSTRACT FROM AUTHOR]

Published
2023
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