256 results on '"van Delft, Joost"'
Search Results
2. Integrating multiple omics to unravel mechanisms of Cyclosporin A induced hepatotoxicity in vitro
3. Interindividual variation in response to xenobiotic exposure established in precision-cut human liver slices
4. A review on ochratoxin A transcriptomic studies
5. New insights into BaP-induced toxicity: role of major metabolites in transcriptomics and contribution to hepatocarcinogenesis
6. Interindividual variation in gene expression responses and metabolite formation in acetaminophen-exposed primary human hepatocytes
7. Cyclosporine A treated in vitro models induce cholestasis response through comparison of phenotype-directed gene expression analysis of in vivo Cyclosporine A-induced cholestasis
8. Proteomics in the search for mechanisms and biomarkers of drug-induced hepatotoxicity
9. Transcriptome Analysis in Peripheral Blood of Humans Exposed to Environmental Carcinogens: A Promising New Biomarker in Environmental Health Studies
10. Effect of Trichostatin A on miRNA expression in cultures of primary rat hepatocytes
11. Biotransformation pathway maps in WikiPathways enable direct visualization of drug metabolism related expression changes
12. A toxicogenomics-based parallelogram approach to evaluate the relevance of coumarin-induced responses in primary human hepatocytes in vitro for humans in vivo
13. Oxidative stress induced by potassium bromate exposure results in altered tight junction protein expression in renal proximal tubule cells
14. Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data
15. Comparison of hepatocarcinogen-induced gene expression profiles in conventional primary rat hepatocytes with in vivo rat liver
16. Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010
17. Mechanisms of colorectal and lung cancer prevention by vegetables: a genomic approach
18. Evaluation of database-derived pathway development for enabling biomarker discovery for hepatotoxicity
19. Characterisation of cisplatin-induced transcriptomics responses in primary mouse hepatocytes, HepG2 cells and mouse embryonic stem cells shows conservation of regulating transcription factor networks
20. Vegetables affect the expression of genes involved in carcinogenic and anticarcinogenic processes in the lungs of female C57BI/6 mice
21. Vegetables affect the expression of genes involved in anticarcinogenic processes in the colonic mucosa of C57BI/6 female mice
22. Gender-specific transcriptomic response to environmental exposure in flemish adults
23. Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models
24. RNA-Seq Provides New Insights in the Transcriptome Responses Induced by the Carcinogen Benzo[a]pyrene
25. Performance of in vitro γH2AX assay in HepG2 cells to predict in vivo genotoxicity
26. SFTG international collaborative study on in vitro micronucleus test: II. Using human lymphocytes
27. ʼOmics analysis of low dose acetaminophen intake demonstrates novel response pathways in humans
28. Human Embryonic Stem Cell Derived Hepatocyte-Like Cells as a Tool for In Vitro Hazard Assessment of Chemical Carcinogenicity
29. Deregulation of Cancer-Related Pathways in Primary Hepatocytes Derived from DNA Repair-Deficient Xpa−/−p53+/− Mice upon Exposure to Benzo[a]pyrene
30. Response to Pathophysiological Relevance of Proteomics Investigations of Drug-Induced Hepatotoxicity in HepG2 Cells
31. Proteomics Investigations of Drug-Induced Hepatotoxicity in HepG2 Cells
32. Concentration-dependent gene expression responses to flusilazole in embryonic stem cell differentiation cultures
33. Application of toxicogenomics in hepatic systems toxicology for risk assessment: Acetaminophen as a case study
34. Evaluation of Developmental Toxicant Identification Using Gene Expression Profiling in Embryonic Stem Cell Differentiation Cultures
35. Transcriptomic Profile Indicative of Immunotoxic Exposure
36. Time Series Analysis of Benzo[A]Pyrene-Induced Transcriptome Changes Suggests That a Network of Transcription Factors Regulates the Effects on Functional Gene Sets
37. Monitoring Developmental Toxicity in the Embryonic Stem Cell Test Using Differential Gene Expression of Differentiation-Related Genes
38. Comparison of HepG2 and HepaRG by Whole-Genome Gene Expression Analysis for the Purpose of Chemical Hazard Identification
39. Global Gene Expression Analysis Reveals Differences in Cellular Responses to Hydroxyl- and Superoxide Anion Radical–Induced Oxidative Stress in Caco-2 Cells
40. Discrimination for Genotoxic and Nongenotoxic Carcinogens by Gene Expression Profiling in Primary Mouse Hepatocytes Improves with Exposure Time
41. Potential role of cytochrome P450-1B1 in the metabolic activation of 4-aminobiphenyl in humans
42. Parallelogram Approach Using Rat-Human In Vitro and Rat In Vivo Toxicogenomics Predicts Acetaminophen-induced Hepatotoxicity in Humans
43. Interactions between polycyclic aromatic hydrocarbons in binary mixtures: Effects on gene expression and DNA adduct formation in precision-cut rat liver slices
44. Gene expression changes induced by ochratoxin A in renal and hepatic tissues of male F344 rat after oral repeated administration
45. Genomic analysis suggests higher susceptibility of children to air pollution
46. Binary PAH mixtures cause additive or antagonistic effects on gene expression but synergistic effects on DNA adduct formation
47. In vitro gene expression data supporting a DNA non-reactive genotoxic mechanism for ochratoxin A
48. Cigarette smoke-induced differential gene expression in blood cells from monozygotic twin pairs
49. Modulation of gene expression and DNA-adduct formation in precision-cut liver slices exposed to polycyclic aromatic hydrocarbons of different carcinogenic potency
50. Modulation of gene expression and DNA adduct formation in HepG2 cells by polycyclic aromatic hydrocarbons with different carcinogenic potencies
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