Fischl, Margaret A., Richman, Douglas D., Greico, Michael, Gottlieb, Michael S., Volberding, Paul A., Leedom, John M., Groopman, Jerome E., Mildvan, Donna, Schooley, Robert T., Jackson, George G., Durack, David T., King, Dannie, and Laskin, Oscar L.
The article presents a reprint of the article "The Efficacy of Azidothymidine (AZT) in the Treatment of Patients With AIDS and AIDS-Related Complex A Double-Blind, Placebo-Controlled Trial," by Margaret A. Fischl et al, which appeared in the July 23, 1987 issue of New England Journal of Medicine. AIDS is characterized by severe immunodeficiency, life-threatening opportunistic infections, neoplasia, and a fatal outcome. The underlying immune defect in AIDS is caused by infection with human retrovirus--human immunodeficiency syndrome (HIV). In addition, infection with this virus causes a debilitating condition known as the AIDS-related complex.