1. Novel Electrochemical Biosensors for Clinical Assays.
- Author
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Guerrieri, Antonio and Guerrieri, Antonio
- Subjects
Technology: general issues ,1-methoxy-5-ethyl phenazinium ethyl sulfate ,Internet of Things ,WiFi portable potentiostat ,alkaline phosphatase ,alternating current electrokinetic effects ,amperometric detection ,analytical methods ,aptamer ,bio-functionalization optimization ,biomarkers ,biomarkers for infectious diseases ,biomedical engineering ,biosensor ,biosensors ,breast cancer ,capacitive sensing ,carbon dots ,choline analysis ,choline biosensor ,choline oxidase ,competitive electrochemical immunosensor ,cost-effective biosensors ,disposable enzyme sensor ,dual electrode biosensor ,electrochemical biosensor ,electrochemical enzyme sensor ,electrochemical sensor ,electrochemical tools ,electrochemistry ,electrophysiology ,electropolymerized non-conducting polymer ,enzyme ,enzyme immobilization ,flow injection analysis ,folic acid ,fructosyl peptide oxidase ,glucose dehydrogenase ,human epididymis protein 4 ,immobilization ,impedance ,in situ detection ,lab-on-a-chip ,labeling ,lactate oxidase ,magnetic NPs ,miRNA sensing ,micro-electrode array ,molecularly imprinted polymers (MIPs) ,nanobiosensors ,nanomaterial ,nanoparticles (NPs) ,neural circuit recognition ,norepinephrine ,on-board calibration ,optogenetics ,overoxidized polypyrrole ,overoxidized polypyrrole film ,phosphatidylcholine ,phosphocholine analysis ,phospholipase D assay ,point-of-care diagnostics ,real samples ,self-assembled monolayers (SAMs) ,signal amplification ,simultaneous determination ,surface imprinted polymers (SIPs) ,surface plasmon resonance ,tyrosinase ,vascular endothelial growth factor ,voltammetry ,zinc finger protein - Abstract
Summary: Biosensors, i.e., devices where biological molecules or bio(mimetic)structures are intimately coupled to a chemo/physical transducer for converting a biorecognition event into a measurable signal, have recently gained a wide (if not huge) academic and practical interest for the multitude of their applications in analysis, especially in the field of bioanalysis, medical diagnostics, and clinical assays. Indeed, thanks to their very simple use (permitting sometimes their application at home), the minimal sample pretreatment requirement, the higher selectivity, and sensitivity, biosensors are an essential tool in the detection and monitoring of a wide range of medical conditions from glycemia to Alzheimer's disease as well as in the monitoring of drug responses. Soon, we expect that their importance and use in clinical diagnostics will expand rapidly so as to be of critical importance to public health in the coming years. This Special Issue would like to focus on recent research and development in the field of biosensors as analytical tools for clinical assays and medical diagnostics.