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A definition of the term "vascular endothelial growth factor" is presented. It refers to growth promoters with vascular permeability enhancing factors. They act almost exclusively on endothelial cells and is expressed by almost all cell types with the exception of endothelial cells which express only marginal amounts of the growth factor.

A definition of the term "vascular endothelial growth factor" is presented. It refers to a group of at least 4 growth factors VEGF-A, -B, -C and -D. They exert their biological functions as homodimers, and act almost exclusively on endothelial cells.

An encyclopedia entry for placenta growth factor is presented.

A definition of the term "lymphangiogenesis" is presented. It refers to the growth of lymphatic vessels controlled by the interaction of vascular endothelial growth factor(VEGF)-C and VEGF-D with the receptor VEGF-R3 on lymphatic endothelial cells.

A definition of the term "VEGF" is presented. It refers to an inducer of endothelial cell proliferation and migration. The binding of VEGF to the receptor tyrosine kinases on vascular endothelial cells promotes their proliferation and leads to vessel formation.

A definition of the term "VEGF receptor" is presented. It refers to an endothelial membrane receptor that interacts with VEGF as it is produced by many tumors and stimulates tumor-associated neo-angiogenesis.