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This paper investigates ontology-based approaches for representing information semantics and in E-learning system. A general E-learning system engineering (ESE) knowledge representation scheme, called an ESE ontology model, to facilitate communication and information exchange in heterogeneous E-learning systems. The proposed approach focuses on how to support the integration of heterogeneous E-learning systems, and how to complete information autonomy allowing the individual learners to keep their own information models rather than requiring them all to adopt standardized terminology. Meanwhile, a communication model Based on SOAP and ontology, is designed for heterogeneous information systems interoperable communications. A prototype interface has been developed to validate the communication model. [ABSTRACT FROM AUTHOR]