14 results on '"CARCINOGENICITY"'
Search Results
2. Differential Effects of Content-Oriented versus User-Oriented Social Media on Risk Perceptions and Behavioral Intentions.
- Subjects
SOCIAL media ,RISK perception -- Social aspects ,INTERPERSONAL relations ,CARCINOGENICITY - Abstract
Despite the increasing importance of social media in risk and crisis situations, little is known about which types of social media are more influential in predicting risk perceptions and behaviors. This study examines the distinct roles of different social media platforms in predicting risk perception, as well as the underlying mechanism by which social media exposure leads to greater levels of risk-preventive behavioral intentions. Analyzing survey data from 688 adults from the general population of South Korea in the context of carcinogenic hazards, we found that content-oriented social media exposure influenced both personal-level and societal-level risk perceptions. In addition, content-oriented social media exposure influenced behavioral intentions indirectly through risk perceptions. However, user-oriented social media exposure had no impact on risk perceptions nor on behavioral intentions, either directly or indirectly through risk perceptions. [ABSTRACT FROM AUTHOR]
- Published
- 2018
3. RESPONSES OF WHEAT AND CUCUMBER PLANTS ON THE TREATMENT WITH NEWLY DEVELOPED HUMIC SUBSTANCES CONTAINING FERTILIZER.
- Author
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Galieva, Gulnaz, Akhtyamova, Alina, Galitskaya, Polina, and Selivanovskaya, Svetlana
- Subjects
MORPHOMETRICS ,CROPS ,FERTILIZERS ,CARCINOGENICITY ,MUTAGENICITY testing - Abstract
Humates are substances possessing high physiological activity, contributing to the photosynthetic yield in plants and having no carcinogenicity or mutagenicity. It is the combination of these unique properties that makes humates promising plant growth and development stimulators. Within the framework of the present investigation the efficiency of application of two humate products has been assessed, and a comparative analysis of their influence on the growth and development of agricultural crops has been carried out. Commercial peat based products EDAGUM®SM and HUMAT K have been chosen as the subjects of research. To study their influence on the growth and development of plants, laboratory- induced germination, germination, plant survival and morphometric parameters were determined in the course of the experiments. To evaluate the photosynthetic rate, total plant leaf chlorophyll (a and b) content has been determined. EDAGUM®SM has shown greater positive influence on the survival of both plants, compared to HUMAT K. The use of neither of the preparations influenced the germination, morphometric parameters or biomass of the plants. EDAGUM®SM influenced positively on total chlorophyll content in wheat leaves. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF
4. Studying the MicroRNA Role as a Survival Predictor and Revealing Its Part in Malignancy Level Determination in Patients with Supratentorial Gliomas of Brain.
- Author
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Stupak, E. V., Veryaskina, Yu. A., Titov, S. E., Achmerova, L. G., Stupak, V. V., Dolzhenko, D. A., Rabinovich, S. S., Narodov, A. A., Ivanov, M. K., Zhimulev, I. F., and Kolesnikov, N. N.
- Subjects
MICRORNA ,NON-coding RNA ,CARCINOGENESIS ,CARCINOGENICITY ,BIOMARKERS - Abstract
The numerous data show, that microRNA (miRNA) are direct participants of carcinogenesis. Also miRNA plays the role of a diagnostic and prognostic marker for different types of cancer, including gliomas. The aim of this research is to make the comparative analysis of 10 micro RNA (miR-124, -125b, -16, -181b, -191, -21, -221, -223, -31 and -451) expression profiles. The analysis was made for gliomas with different malignancy degree, then compared with the samples of the adjacent not changed tissues (n = 90). During the study the specific profiles of miRNA expression for various histotypes of tumors were revealed. It was determined, that miRNA acts as a predictor of patient survival in the cases with malignant supratentorial brain tumors. The diagnostic approaches based on miRNA expression profile were designed. It will help to determine the malignancy level and to predict the course of the disease. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
5. CARCINOGENIC RISK ASSESSMENT OF HEAVY METALS CONTAMINATION DUE TO ACCIDENTAL OIL SPILLS ON SOIL.
- Author
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Stoian, Mihaela Alexandra, Cocârţă, Diana Mariana, Badea, Adrian, and Dumitru, Delia Micaela
- Subjects
SOILS ,HYDROCARBONS ,POLYCHLORINATED biphenyls ,SOIL pollution ,CARCINOGENICITY - Abstract
Oil spills are the main cause of pollution with crude oil. Contamination with crude oil affects the environment (soil underground and surfaces, groundwater and water surface, air quality), plants, and health of animals and humans. Soil pollution with crude oil implies contamination with Polychlorinated Biphenyls, Polycyclic Aromatic Hydrocarbons, Monocyclic Aromatic Hydrocarbons and different heavy metals. The contaminated soil investigated in the framework of the present work was collected from a bioremediation platform, before that soil is undergoing to the remediation treatment. Initially, soil was excavated from a contaminated area with oil spills. The currently paper is illustrating the potential risks on human health of heavy metals from oil contaminated soil. Known heavy metals as carcinogenic to humans were analyzed: Arsenic, Cadmium, Hexavalent Chromium, Nickel and Lead. Concentrations of these heavy metals from soil samples were identified and were compared with thresholds for a sensitive and less sensitive use of soil (alert and intervention) according to the Romanian regulation in force. The values for contaminants concentration do not exceed the alert or intervention thresholds, excepting Lead with a measured concentration of 53.91 mg/kg
d.w . Lead measured concentration was between alert and intervention thresholds, for sensitive use of soil (50 mg/kgd.w for alert, respectively 250 mg/kgd.w for intervention) and lower respect to the less sensitive use of soil (100 mg/kgd.w for alert, respectively 1000 mg/kgd.w for intervention). Carcinogenic risk to humans was quantified through the approach that is using the evaluation of exposure of all the relevant exposure pathways according to the considered scenarios: industrial or agricultural. For the assessment of the carcinogenic risk associated to soil contamination with heavy metals, in case of the industrial considered scenario, two pathways of exposure were considered: ingestion and dermal contact. The agricultural scenario involves the assessment of the exposure through ingestion of contaminated soil (accidentally) and ingestion of vegetable and animal products. The estimated carcinogenic risk associated to exposure to soil contaminated with heavy metals was 7.29 x 10-6 for industrial use of soil and 3.77 x 10-4 for agricultural use of soil, which exceed the acceptable value for risk of 10-6 indicated by the World Health Organization. The obtained results suggest that a remediation treatment must be applied to the contaminated soil, independently of the considered scenario. [ABSTRACT FROM AUTHOR]- Published
- 2017
- Full Text
- View/download PDF
6. Removal of Copper from Aqueous Solution Using Perlite.
- Author
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TANAYDIN, Mehmet Kayra, BAKICI TANAYDIN, Zümra, İNCE, Muharrem, and DEMİRKIRAN, Nizamettin
- Subjects
INDUSTRIAL wastes ,POLLUTANTS ,HEAVY metals ,METAL ions ,CARCINOGENICITY - Abstract
The wastewaters containing organic and inorganic pollutants after many industrial processes such as metal plating, mining, textile, alloy, battery and industrial chemicals, are often discharged to environment. Heavy metals among these pollutants have highly stable, toxic, non-degradable and carcinogenic characters. They affect not only ecological system, but also human health and many life forms. Therefore, these contaminants should be eliminated or reduced to allowable levels before releasing to environment. Most of heavy metals have toxic character even at low concentrations of about 0.1-0.3 ppm. Treatment technologies such as filtration, ion exchange, precipitation, electrodeposition, reverse osmosis, sedimentation, and adsorption have been applied for removal of heavy metals from aqueous solutions. Adsorption is one of the most common and widely applied methods to eliminate the metal ions from waste solutions because of its simplicity and cost effectiveness. Activated carbon, clay minerals, ion exchange resins and various agricultural residues can be used as adsorbent materials in this process [1-3]. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
7. SAMPLE PREPARATION PROCEDURE FOR THE DETERMINATION OF POLYCYCLIC AROMATIC HYDROCARBONS IN DUST PARTICLES.
- Author
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Sarcakova, Eliska, Pertile, Eva, Surovka, Dalibor, and Jochymkova, Lenka
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AROMATIC compounds ,DUST ,CARCINOGENICITY ,ECOLOGY ,ENVIRONMENTAL protection - Abstract
Polycyclic aromatic hydrocarbons are among carcinogenic micro pollutants, which are resistant in the environment. Due to their lipophilic nature and high stability, they accumulate in living organisms and in all parts of the environment. This study focuses on the preparation methods of dust particles for the size fraction below 0.063 mm over the 0,063 mm from the burning slag heap Ema, (the Czech Republic), to determine the concentration of selected PAHs by HPLC with fluorescence detection. This study deals with the preparatory processes for the determination of selected PAHs by the HPLC method with fluorescence detection. The most important factors of sample preparation include the collection, which is mainly influenced by physical-chemical factors. Samples were collected by a method using a passive barrier between the sampled and the sampling medium. This study also presents a list of extraction procedures used for the determination of PAHs along with the used clean-up and fractionation procedures so as to create the best possible methodology for the determination of PAHs in the studied samples from the burning slag heap Ema. [ABSTRACT FROM AUTHOR]
- Published
- 2014
8. Molecular Engineering of Sustainable Synthetic Colorants.
- Author
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Freeman, Harold S.
- Subjects
DYES & dyeing ,AZO dyes ,TEXTILES ,CARCINOGENICITY ,MUTAGENICITY testing ,ENVIRONMENTAL chemistry - Abstract
While the fastness properties of synthetic dyes are essential to their commercial utility, the need to avoid harming human health and the environment is an important requirement in the commercial use of technically viable synthetic dyes and their auxiliary chemicals. For textile dyes, safety is often demonstrated by conducting tests involving ecotoxicity and genotoxicity (e.g. mutagenicity and carcinogenicity) and aquatic toxicity. The genotoxicity of synthetic dyes became a matter of concern when it was discovered that certain azo dye precursors were human carcinogens. This outcome led to extensive testing of azo dyes and their aromatic amine precursors for mutagenic and/or carcinogenic potential. Although those studies were aimed mainly at risk assessment and product regulation, the utility of the resultant data for the design of alternatives to environmentally unfriendly compounds was also examined. The present paper provides an overview of studies pertaining to the environmental chemistry of azo dyes, by far the major class of textile dyes. Specifically, a summary of studies conducted largely in our laboratory since the inception of the dye chemistry program more than 25 years ago is presented. Covered are studies pertaining to the design of textile dyes that pose low risk to human health and the environment, with emphasis on identifying potential alternatives to dyes and dye intermediates that raised genotoxicity or aquatic toxicity concerns. [ABSTRACT FROM AUTHOR]
- Published
- 2014
9. SCANDIUM, ELEMENT OF SURPRISES.
- Author
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Bordean, Despina-Maria, Cojocariu, Adrian, Horablaga, Marinel, Cojocariu, Luminita, Alda, Simion, Nica, Dragos, Alda, Liana, and Borozan, Aurica Breica
- Subjects
SCANDIUM ,RARE earth metals ,SOIL crusting ,MINES & mineral resources ,CARCINOGENICITY ,FOOD chains - Abstract
Scandium, the Mendeleev's hypothetical element "eka-boron" is considered one of the Rare Earth Elements (REE) group, in abundance in the earth's crust of 16 ppm. The specific health effects of superior concentrations of REEs in the environment from mining REE containing materials are not well understood. The aim of the present study was to conduct a more complete literature review of health and ecological impacts of scandium. Some studies affirm that scandium has no known biological role and it seems that only trace amounts reach the food chain. One of the surprises is that diluted solutions of scandium sulfate induce germination of plant seeds. According to some researcher only very few analyzed plants presented scandium. It is considered that scandium is not toxic, but some studies suggest that a few scandium compounds might be carcinogenic [ABSTRACT FROM AUTHOR]
- Published
- 2013
10. HEALTH AND ENVIRONMENTAL RISKS OF CYTOSTATICS PLATINUM GROUP RESIDUES.
- Author
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Zimova, Magdalena, Wittlingerova, Zdenka, Cidlinova, Anna, Petruzelkova, Anna, Matĕjů, Ladislava, Splichalova, Jana, and Wranova, Kateřina
- Subjects
ANTINEOPLASTIC agents ,PLATINUM ,BIOLOGICAL products ,INDUSTRIAL wastes ,ENVIRONMENTAL risk ,SEWAGE sludge ,CARCINOGENICITY - Abstract
Interest in waste drugs in relation to their negative impact on the environment is increasing during last years. Reason for that situation is high production and consumption of drugs in the world and ineffective treatment of sewage containing drugs. Broad range of pharmaceuticals can be detected in aquatic environment now. Hospitals use a great variety of substances for medical purposes, as diagnostics as well as for therapy, care and research. Various groups of pharmaceuticals like analgesics, antibiotics, lipid lowering agents, psychotropic drugs, cytostatic agents, contrast media, as well as disinfectants can be detected in wastewater from hospitals and to some extent even in surface and ground water. The main route of human pharmaceuticals to the environment is through faeces to sewage. Drugs are not easily degraded during wastewater treatment. They may subsequently cause contamination of the environment including the food chain, when sewage sludge is used as fertilizer of agricultural land. Due to growing consumption of cytostatics containing heavy metals the threat of heavy metals to environment is increasing. Removal of cytostatics from wastewaters is not efficient as well as natural attenuation processes in environmental matrices. The project "Research of technologies and methods of removing heavy metals from the Platinum group of biological waste and their recycling options" addresses this issue. The project proposes a solution for minimization of content of Platinum drugs and their metabolites in environmental components after application of these drugs. The project proposes further a detailed study of Platinum drugs in environment. Obtained results show the contamination of working environment in hospitals. Contamination was found in 88% of samples. Analysis was performed by ICP - MS (plasma mass spectrometry), which allowed detection of 0.50 ng/l of Platinum (5 pg/survey sample). It was also demonstrated for waste water, where Pt levels ranged from 0.5 to 1.0 µm/l. Sewage sludge contains 0.1 mg/kg. Goals of the project are: * Reduction of the content of Platinum drugs and their metabolites * Development of analytical methods for determination of Platinum compounds in body fluids of treated patients * Development of method for reduction of Platinum compounds content in body fluids of patients * Health and environmental risks assessment of spread of chemotherapeutic agents in the environment New standards or amendments will be drafted aimed to reduction of health and ecological risk with respect to potential mutagenicity and carcinogenicity of Platinum compounds in biological wastes. [ABSTRACT FROM AUTHOR]
- Published
- 2012
- Full Text
- View/download PDF
11. ANALYSIS OF OCCULT TUMOUR TRIAL DATA WITH VARYING LETHALITY.
- Author
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RAI, S. N., SUN, J., and HUNT, D.
- Subjects
CARCINOGENS ,DEATH rate ,AUTOPSY ,FOOD additives ,CARCINOGENICITY - Published
- 2002
12. EVALUATION OF THE PERFORMANCE OF AN ECO-FRIENDLY AUXILIARY BY COLOR MEASUREMENT TECHNIQUES.
- Author
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Jahagirdar, Chandrahas J. and Kaushik, Neeti H.
- Subjects
CHEMICAL research ,TEXTILES ,COLORIMETRY ,DYES & dyeing ,POLYESTER fibers ,ELECTROLYTES ,CARCINOGENICITY ,COLORING matter - Abstract
The article examines the performance of eco-friendly auxiliary Sunnysyst-800 through color measurement techniques in the U.S. The study shows that Sunnysyst-800 gives higher color value in Disperse dyeing on polyester fabrics. It notes that Sunnysyst-800 can minimize the concentration of electrolyte used aside from giving level dyeing with higher color value. Moreover, the use of lesser quantity of electrolyte can help preserve the environment by reducing the Total Dissolved Solids (TDS) of effluents.
- Published
- 2000
13. DIRECT DYES FROM NONGENOTOXIC DIAMINES.
- Author
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Jin-Seok Bae and Freeman, H. S.
- Subjects
DYES & dyeing ,ETHANES ,BENZIDINE ,ELECTROSPRAY ionization mass spectrometry ,COLORFASTNESS (Textiles) ,TEXTILES ,SPECTRUM analysis ,CARCINOGENICITY - Abstract
The article highlights the study on the synthesis and evaluation of direct dyes that employs 2,2'-dimethyl- 5,5-dipropoxybenzidine and 5,5'-dipropoxybenzidine as alternatives to benzidine in the U.S. It states that negative ion electrospray mass spectrometry (ESMS) has been used to confirm the structures of dye. It emphasizes that direct dyes having comparable colors and fastness properties to commercial direct dyes can be prepared using diamines 2,2'-dimethyl-5,5'-dipropoxybenzidine and 5,5'-dipropoxybenzidine.
- Published
- 2000
14. FATE OF FORMALDEHYDE IN TEXTILE CONSUMER USE.
- Author
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JACO, PAMELA J.
- Subjects
FORMALDEHYDE ,TEXTILES ,TEXTILE product treatments ,CARCINOGENESIS ,CARCINOGENICITY ,LAUNDRY - Abstract
DUE TO recent interest in the toxicity and carcinogenicity of formaldehyde, numerous studies have been undertaken to determine the effect of formaldehyde released into our environment. The quantity of formaldehyde produced is relatively low and is known for typical formaldehyde based resin treated fabrics. The extent of a consumer's exposure to formaldehyde during the lifetime of a garment is not known. The effect of consumer use upon formaldehyde release also has not been determined. The results of investigations simulating the laundering and storage conditions utilized by consumers over a three month period will be presented. Mechanisms that explain the observed differences in formaldehyde released by dimethlol-dihydroxyethyleneurea (DMDHEU) versus methylated dimethylol-dihydroxyethyeneurea (MDMDHEU) treated fabrics during these laundering and storing cycles will be proposed. [ABSTRACT FROM AUTHOR]
- Published
- 1981
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