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The aim of this work is to study the condensation reaction of some aldehydes with amides - urea and thiourea, to create new means for the rubber industry based on local raw materials, to develop a highly efficient technology for their production. The reactions of condensation of formaldehyde aldehydes, acetic and crotonic aldehyde (croton fraction) with urea and thiourea are investigated. The technological parameters of the process were studied, it was found that the condensation of aldehydes with amines and amides first forms unstable amino alcohols - hydroxy derivatives of urea (thioureas), which, when heated, transform into imines and imides. Condensation of urea (thiourea) with the croton fraction occurs with the formation of a product of linear and cyclic structure. The resulting products were tested as an accelerator for vulcanization of rubbers, which are not inferior to an industrial reagent in their physical, mechanical and operational characteristics. [ABSTRACT FROM AUTHOR]

Chalcones are the significant constituent of natural sources. Chalcones posses 1,3-diaryl-1-ones frame which withdraws the recognition of biological importance. Chalcones are not possible to separate from plants because it is transformed into flavonones due to the presence of enzyme chalcone synthetase. Chalcones are prepared by the Claisen- Schimdt condensation of equimolar ratios of aldehyde and ketone in presence of base. With this vision we accounted here the synthesis of some novel chalcones via Clasien--Schimdt condensation of substituted ketones containing hydroxy, chloro, fluoro groups and 4-(4-Methyl-piperazin-1-yl)-benzaldehyde in presence of alkali at room temperature. These recently synthesized γ, β unsaturated compounds that is chalcones were screened for their antimicrobial studies which show modest to good activity. [ABSTRACT FROM AUTHOR]