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Scottish hill sheep systems are comparable to other extensive sheep systems in harsh environments around the world. They face a number of difficulties, including low productivity, poor economic viability, labour availability and capability, and ensuring good animal welfare. They do however, play an important role for rural communities, environmental management, and production of sheepmeat and breeding animals. Exploring alternative approaches, such as Precision Livestock Farming (PLF), to overcome these difficulties is essential. PLF has been successfully applied to intensive systems but few examples exist for extensive systems, such as hill sheep systems. Pregnancy supplementation and retention and culling decision making are both key processes within hill sheep systems. How they occur can have major impacts on productivity and profitability of the system. Therefore, the aim of this thesis was to investigate and understand the capacity for application and potential impacts of PLF for hill sheep systems, when considered for two challenge areas: ewe pregnancy supplementation, and ewe retention and culling decision making. This research was carried out on a 2,200 ha hill sheep research farm, in the West Highlands of Scotland. The majority of the land was unimproved hill pasture and around 230 ha of improved fields and semi-improved parks. Methods were applied and data collected from October 2013 to October 2016 from a long-term performance recorded research flock of 600 Scottish Blackface and 300 Lleyn breeding ewes. All 900 breeding ewes were assigned to one of two management approaches. The first approach was a conventional one, where management decisions were carried out at a flock level, or without the assistance of Electronic Identification (EID) technology, and was comparable to conventional hill sheep systems. The other approach was PLF, where management decisions were carried out at an individual animal level, assisted by EID and weighing technology. A PLF approach was applied to allocate supplementation to pregnant hill ewes based on liveweight change. Inputs required (feed) and outputs (number of lambs born and liveweight of lambs) were similar between ewes allocated supplementation in the PLF approach and those allocated supplementation based on a stockperson's assessment of their condition. However the PLF approach successfully moved more individual ewes out of higher supplementation levels. This PLF supplementary approach could be consistently applied to any sheep system and constitutes a framework which can be easily modified and further developed. The work also demonstrated that liveweights could be collected quickly and reliably using automated weighing technology. Such technology and liveweight data are likely to be key for future developments of PLF approaches for hill sheep systems. The second challenge targeted was retention and culling decision making of ewes from the breeding flock. Questionnaires carried out with stockpeople revealed many different reasons are used to make culling decisions. These reasons were mostly based on the stockperson's opinion and subjective assessment, and that little recorded information was used to inform decision making. Culling at a fixed age occurs on some hill sheep systems but this limits longevity and the associated benefits of increased longevity. Within the research flock, used in this thesis, the majority of ewes left the flock as a result of culling decisions and not because of death. However, findings showed that ewes retained beyond a standard cull age, were able to perform as well or better than younger ewes. A flock that did not cull based on age had the potential to improve profitability. Comparison between individual ewes' performance, genetic and appearance attributes and their following year's performance, found that many common culling reasons (including stockpersons opinion, number of lambs previously weaned, ewe age and ewe appearance) had little association with future ewe performance. Conversely, promising attributes included liveweight, Body Condition Scores and liveweight change, all of which require data to be collected prior to any decision making. A PLF approach, that uses data collected about a ewe over its lifetime to make retention and culling decisions, has the potential to improve productivity and profitability of the system. In conclusion, this thesis established that PLF can be applied to hill sheep systems using commercially available EID and automated weighing technology, as well as individual sheep data to inform decision making. Such application has the potential to improve productivity and profitability. For PLF to be widely adopted onto commercial sheep farms, further research will be required to demonstrate greater benefits to the system, including labour and welfare, and to better understand farmers' motivation towards uptake. Adoption of PLF approaches into hill sheep systems has the potential to benefit individual farms and the industry as a whole.

Four interfaces were developed to factorially apply two principles of ecological interface design (EID; direct perception and direct manipulation) to a flexible manufacturing system (FMS). The theoretical foundation and concepts employed during their development, with findings related to more significant issues regarding interface design for complex socio-technical systems, are discussed. Key aspects of cognitive systems engineering (CSE) and EID are also discussed. An FMS synthetic task environment was developed, and an experiment was conducted to evaluate real-time decision support during supervisory operations. Participants used all four interfaces to supervise and maintain daily part production at systematically varied levels of difficulty across sessions. Significant results provide evidence that the incorporation of direct perception and direct manipulation in interface design produced an additive effect, allowing for greater support for the supervisory agents.

This study examined how gender, age, pubertal status, and obesity influence endothelium-independent dilation (EID) in youth. Three hundred twenty-two healthy youth (142 females), aged 9 to 18 years (mean±SEM, age=14.1±0.14years) were included. The change in brachial artery diameter following administration of 0.3mg of sublingual nitroglycerin was measured using conventional ultrasound scanner. Multiple linear regression models were created using the predictors gender, age, BMI-percentile, percent body fat and baseline diameter. Differences between gender, pubertal status and BMI category was conducted using one-way ANOVA. Females had higher EID-area under the curve (EID-AUC) compared to males (p=0.012) but not EID% (p=0.112). Age was a significant predictor of EID% (p=0.04) and EID-AUC (p=0.02) in females but not males. No differences in EID% or EID-AUC were observed across Tanner stage or BMI category. These data suggest that gender differences in EID are apparent early in life, with aging-related changes observable in females, but not males.

Delay and Disruption Tolerant Networking (DTN) was developed to deliver network communications to so-called "challenged environments." These include space, military, and other networks that can be described as having extremely long link delay and frequent disconnections. The DTN paradigm implements a store-and-forward network of nodes to overcome these limited environments as well as delivering "bundles" of data instead of packets. The bundles nominally contain enough data to constitute an entire atomic unit of communication. DTN introduces the Endpoint Identifier (EID) to identify bundle Agents or groups. The EID can imply naming, addressing, routing and network topology, but these features and flexibility come at the cost of verbosity and a per-packet overhead introduced by large and descriptive EIDs.In this document, we apply lossless text compression to EIDs using Zlib's DEFLATE algorithm. We develop a novel method for generating a large sample of verbose EIDs based upon Apache access logs, allowing testing over a larger, more varied, and more realistic data set than would be possible with the current DTN testing networks. Analysis of the processing overhead and compression ratio lead us to the conclusion that Zlib reduces the overhead of EIDs substantially. By compressing the dictionary, more featureful EIDs can be used without increasing overhead in the form of larger bundle dictionaries due to syntactical verbosity.

Peak brachial artery dilation post-nitroglycerin (NTG) administration occurs between 3 and 5-min in adults. The purpose of this study was to identify the time to peak dilation response to sublingual NTG (0.3 mg) in youth. Endothelium-independent dilation (EID) was measured in 198 healthy (113 males, 85 females) youth (6-18 yrs) via ultrasound imaging of the brachial artery following NTG administration up to 5-min. Time to peak EID was 4-min, 28-sec, following NTG administration. There was a significant (p