1. Longitudinal performance of Neuropsychological Assessments in Parkinson’s Disease.
- Author
-
Muayqil, Taim
- Subjects
- Frontal Assessment Battery, Mini-Mental State Exam, Cognitive impairment, Parkinson's Disease, Dementia Rating Scale, Clock Drawing test
- Abstract
Abstract: Parkinson’s disease (PD) involves the motor system and can lead to dementia. Dementia incidence among 102 non-demented participants (52 PD and 50 controls) followed prospectively over three years was assessed. Cognition was measured annually using the Clock Drawing Test (CDT), Mini-Mental State Exam (MMSE), Frontal Assessment Battery (FAB) and Dementia Rating Scale (DRS). Mixed-effects model was used to determine the significance of the change in neuropsychological tests (NPT) over time. Incidence of dementia in the PD group was 41.67%. The FAB and DRS showed significant. In the PD subgroup, the copy-CDT (CCDT), FAB and DRS showed decline in patients with incipient dementia (PDID). The FAB and DRS scores correlated in the primary and subgroup analyses. In the subgroup, the CCDT correlated with FAB and DRS. The NPT were useful in discriminating PD from control patients with early cognitive impairments and discriminating PDID from PDND.
- Published
- 2012