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Jerzy SieÅ„ko,1 Maciej Kotowski,1 Anna Bogacz,2 Kacper Lechowicz,3 Sylwester Drożdżal,4 Jakub Rosik,5 Marek Sietnicki,6 Magdalena SieÅ„ko,7 Katarzyna Kotfis3 1Department of General Surgery and Transplantology, Pomeranian Medical University in Szczecin, Szczecin, Poland; 2Department of Pharmacology and Phytochemistry, Institute of Natural Fibers and Medicinal Plants, Poznan, Poland; 3Department of Anaesthesiology, Intensive Therapy and Acute Intoxications, Pomeranian Medical University in Szczecin, Szczecin, Poland; 4Department of Pharmacokinetics and Monitored Therapy, Pomeranian Medical University in Szczecin, Szczecin, Poland; 5Department of Physiology, Pomeranian Medical University in Szczecin, Szczecin, Poland; 6Department of Civil Engineering and Architecture, West Pomeranian University of Technology in Szczecin, Szczecin, Poland; 7Department of Pediatrics, Endocrinology, Diabetology, Metabolic Diseases and Cardiology, Pomeranian Medical University in Szczecin, Szczecin, PolandCorrespondence: Katarzyna KotfisDepartment of Anaesthesiology, Intensive Therapy and Acute Intoxications, Pomeranian Medical University in Szczecin, Al. PowstaÅ„ców Wielkopolskich 72, Szczecin 70-111, PolandTel/ Fax +48 91 466 11 44Email katarzyna.kotfis@pum.edu.plAbstract: Since the beginning of 2020, the whole world has been struggling with the pandemic of Coronavirus Disease 2019 (COVID-19) caused by a novel coronavirus SARS-CoV-2. The SARS-CoV-2 infection depends on ACE2, TMPRSS2, and CD147, which are expressed on host cells. Several studies suggest that some single nucleotide polymorphisms (SNPs) of ACE2 might be a risk factor of COVID-19 infection. Genotypes affect ACE2 structure, its serum concentration, and levels of circulating angiotensin (1-7). Moreover, there is evidence that ACE genotype affects the outcomes of acute respiratory distress syndrome (ARDS) treatment, the most severe consequence of SARS-CoV-2 infection. COVID-19 morbidity, infection course, and morta

Probiotics are live, selected microbial strains that have a beneficial effect on the human body and when introduced into the body, they colonize in the digestive tract, especially in the large intestine, exerting a beneficial effect on the health of the host. The microbial strains, so that they can be included in the probiotics, must be thoroughly tested and meet several conditions. These microorganisms multiply in the gastrointestinal tract and are competitive for pathogenic microorganisms that cause infection. Probiotic bacteria are found in natural yogurts, sour milk, sauerkraut, pickled cucumbers. Many studies show a positive correlation between the consumption of probiotics and the risk of developing certain cancers. Probiotics are most likely to reduce the risk of developing colorectal cancer. DOI: http://dx.doi.org/10.5281/zenodo.1297660

Probiotics are live, selected microbial strains that have a beneficial effect on the human body and when introduced into the body, they colonize in the digestive tract, especially in the large intestine, exerting a beneficial effect on the health of the host. The microbial strains, so that they can be included in the probiotics, must be thoroughly tested and meet several conditions. These microorganisms multiply in the gastrointestinal tract and are competitive for pathogenic microorganisms that cause infection. Probiotic bacteria are found in natural yogurts, sour milk, sauerkraut, pickled cucumbers. Many studies show a positive correlation between the consumption of probiotics and the risk of developing certain cancers. Probiotics are most likely to reduce the risk of developing colorectal cancer. DOI: http://dx.doi.org/10.5281/zenodo.1297660

The cognitive framework seems to comply with the need of interdisciplinary outlook on the issue of emotions, as it itself draws upon findings of psychological, anthropological and philosophical research. Along with undertaking further studies on the conceptualization of emotions in different languages, from the detailed analysis of the repertoire of linguistic means used for talking about emotions to investigation into tendencies to use metaphors or metonymies to talk about emotions, some broader conclusions could be drawn. The greatest challenge seems to be establishing whether there are any cultural (social, economical, conventional, political, religious) conditions that may influence the relevant changes in conceptualizing emotions in different languages and whether it is possible to point to any laws or regularities that would govern these changes.