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Your search keyword '"Dondapati, Srujan Kumar"' showing total 2 results
Start Over Author "Dondapati, Srujan Kumar" Publication Type Electronic Resources
2 results on '"Dondapati, Srujan Kumar"'

1. Label free optical sensor for Avidin based on single gold nanoparticles functionalized with aptamers

Author

Hernandez, Frank Jeyson, Dondapati, Srujan Kumar, Ozalp, V Cengiz, Pinto, Alessandro, O'Sullivan, Ciara K, Klar, Thomas A, Katakis, Ioannis, Hernandez, Frank Jeyson, Dondapati, Srujan Kumar, Ozalp, V Cengiz, Pinto, Alessandro, O'Sullivan, Ciara K, Klar, Thomas A, and Katakis, Ioannis

Abstract

Optical spectroscopy of a single gold nanoparticle, functionalized with an aptamer, is used to sense the specific binding of avidin. Herewith, the field of single noble metal nanoparticle biosensors is extended to the important field of aptamer based assays. The sensitivity of this initial, but not yet optimized apta-nano-sensor is in the range of 20 nM. Due to its nanoscopic size, this single nanoparticle based apta-sensor may be used in nanoscopic volumes such as in array type assays or even inside cells.

Published
2009
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