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Cilj: Incidencija hepatitisa A u našoj zemlji, slično ostalim razvijenim zemljama, niska je zahvaljujući poboljšanju socioekonomskog standarda i higijenskih uvjeta. U razvijenim zemljama svijeta posljednje desetljeće opisane su epidemije hepatitisa A vezane uz „novi”, spolni put prijenosa, poglavito u MSM populaciji (engl. Men Sex Men; MSM) i u osoba s drugim spolno prenosivim infekcijama. Budući da u razvijenim zemljama od hepatitisa A češće obolijevaju osobe odrasle dobi, učestalost komplikacija veća je u odnosu na nerazvijene zemlje gdje je hepatitis A bolest dječje dobi, što je poznato kao „paradoksalni rizik”. Svrha je ovog rada opisati epidemiološke osobitosti i kliničku sliku bolesnika s hepatitisom A u proteklom dvanaestogodišnjem razdoblju. Ispitanici i metode: Istraživanjem je obuhvaćen 21 bolesnik s hepatitisom A liječen u Klinici za infektivne bolesti Kliničkog bolničkog centra Rijeka u razdoblju od 2010. do 2021. godine. Rezultati: Najveći dio oboljelih osoba bio je srednje životne dobi (40 - 49 godina). U razdoblju do 2010. do 2016. godine liječen je 0 - 1 bolesnik s hepatitisom A godišnje, dok je 2017. i 2018. godine liječeno 16 bolesnika i 2019. dva bolesnika. Godine 2020. i 2021., u vrijeme epidemije COVID-19, nismo liječili oboljele od hepatitisa A. Većinu oboljelih činili su muškarci. Uz fekooralni put prijenosa glavni put prijenosa infekcije bio je spolni put u MSM populaciji. Tijek bolesti bio je blag. Zaključci: Epidemiološke značajke bolesnika s hepatitisom A obuhvaćenih studijom zrcale nove epidemiološke trendove hepatitisa A u razvijenim europskim zemljama - s najvećim brojem oboljelih u odrasloj dobi i „novim”, spolnim putem prijenosa infekcije., Aim: Incidence of hepatitis A in our country, like other developed countries, is low due to the improvement of socioeconomic and hygienic standards. However, in the last decade epidemics of hepatitis A related to the "new" sexual route of transmission have been described, mainly in the Men Sex Men (MSM) population. Since in the developed countries hepatitis A occurs more commonly in adults, the frequency of complications is higher compared to underdeveloped countries known as "paradoxical risk". The aim is to characterize current epidemiological features and clinical presentation of hepatitis A infection. Patients and methods: A retrospective study was conducted in the Clinic for Infectious Diseases, University Hospital Centre Rijeka from 2010 to 2021 and included 21 patients with hepatitis A. Results: The age range of patients was six to 70 years, and most patients were middle-aged (40 - 49 years). In the period from 2010 to 2016, 0 - 1 patients with hepatitis A were treated annually while in 2017 and 2018 16 patients were treated, mostly man. Two patients were treated in 2019. while in 2020 and 2021, during COVID-19 pandemic, there were no patients with HAV. In addition to the feco-oral route, the major assumed route of transmission was sexual in MSM population. The course of disease was mild in all patients. Conclusions: Epidemiological characteristics of patients included in the study reflect the new epidemiological trends of hepatitis A in developed countries with most patients being infected in adulthood and the "new" sexual route of transmission.