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Weisheng Xu,1,2,* Wangsheng Xue,1,* Zeyu Zhou,3,* Jiying Wang,1 Hui Qi,1 Shiyu Sun,1 Tong Jin,1 Ping Yao,1 Jian-Yuan Zhao,4 Fuqing Lin1 1Department of Pain Medicine, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, 200072, People’s Republic of China; 2School of Medicine, Tongji University, Shanghai, 200331, People’s Republic of China; 3School of Life Sciences, Fudan University, Shanghai, 200433, People’s Republic of China; 4Institute for Developmental and Regenerative Cardiovascular Medicine, MOE-Shanghai Key Laboratory of Children’s Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200090, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fuqing Lin, Department of Pain Medicine, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, 200072, People’s Republic of China, Email fuqinglin@tongji.edu.cn Jian-Yuan Zhao, Institute for Developmental and Regenerative Cardiovascular Medicine, MOE-Shanghai Key Laboratory of Children’s Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200090, People’s Republic of China, Email zhaojy@vip.163.comBackground: As one of the most frequent complications of type 2 diabetes mellitus (T2DM), diabetic peripheral neuropathy (DPN) shows a profound impact on 50% of patients with symptoms of neuropathic pain, numbness and other paresthesia. No valid serum biomarkers for the prediction of DPN have been identified in the clinic so far. This study is to investigate the potential serum biomarkers for DPN firstly based on 1H-Nuclear Magnetic Resonance (1H-NMR)-based metabolomics technique.Methods: Thirty-six patients enrolled in this study were divided into two groups: 18 T2DM patients without DPN (T2DM group) and 18 T2DM patients with DPN (DPN group). Serum metabolites were measured via 1H-NMR spectros

We report the synthesis of a three-dimensional graphene (3DG)-TiO2 nanocomposite by covalently attaching P25 TiO2 nanoparticles onto pristine 3DG through a perfluorophenyl azide-mediated coupling reaction. The TiO2 nanoparticles were robustly attached on the 3DG surface, with minimal particle agglomeration. In photocatalytic CO2 reduction, the 3DG-TiO2 nanocomposite demonstrated excellent activity, about 11 times higher than that of the P25 TiO2 nanoparticles. The enhanced activity can be partially attributed to the highly dispersed state of the P25 TiO2 nanoparticles on the 3DG substrate. This 3DG-based system offers a new platform for fabricating photocatalytic materials with enhanced activities., QC 20170130

We have proposed and demonstrated a nonlinear polarization-rotation-based fiber laser with two different operation states: passive mode-locking and multiwavelength emission. The intensity-dependent transmission or loss induced by nonlinear polarization rotation accounts for the distinct operation regimes. Our experiment results indicate that both passively mode-locked pulses and continuous-wave multiwavelength can be generated from the same fiber laser just through adjusting polarizations. Another characteristic of the current multiwavelength laser is that the used periodic filter is a birefringence fiber filter, which facilitates all-fiber integration of the fiber laser, so it is a potential multifunction laser source with all-fiber configuration and convenient manipulation. © 2008 IEEE.

Single-mode fibre lasers are a new class of active fibre device, which play a remarkable role in optical fibre communications and sensors. They also exhibit a number of new phenomena, one of the most important being polarisation effects. In this thesis, new unexpected fundamental polarisation effects in fibre lasers have been discovered. The phenomena are fluorescence depolarisation, the existence of orthogonal polarisation eigenmodes, and the dependence of the output polarisation on the pump polarisation state. A unified theoretical model, incorporating the electric dipole model for rare-earth ions in a glass matrix, is formulated. The concept of effective pump power is introduced and can be applied to existing laser theory; thus laser performance characteristics such as thresholds, slope efficiencies and the polarisation state of the output can be predicted accurately. The good agreement between theory and experiment enables the derivation of the polarised cross-section ratio. This has been done for Nd3+ and Er3+ ions in silica fibres. From the theoretical analysis the optimum condition for single polarisation operation is deduced. An effective technique for making single-polarisation single-mode (SPSM) fibre lasers has been developed using an integral fibre polariser. The advantages of this technique are low insertion loss, high polarisation extinction ratio and compatibility with existing single-mode fibre components. Laser-diode-pumped SPSM fibres of high performance, both in continuous-wave and Q-switched operations, have been achieved.