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Background: Chronic Obstructive Pulmonary Disease (COPD) is considered to be a global health problem because of its higher prevalence and mortality rate. Multiple co-morbidities are associated with COPD including lung cancer, anemia, osteoporosis, coronary artery disease, renal dysfunction, diabetes, etc. It is a progressive disease that is particularly common among the elderly age group. Due to the growing number of aging populations worldwide, COPD cases are predicted to rise further. Objectives: The objective of our study is to calculate the age- and sex-specific COPD mortality rate and smoking rate in Japan and compared them to the US. In addition, we also aim to do a meta-analysis of COPD prevalence in Japan and compare it to the US. Methods: We extracted the COPD mortality and smoking dataset for Japan and the US from WHO (World health Organization) database and CDC (Center for Disease Control and Prevention) WONDER ( Wide-Ranging online data for Epidemiologic Research) database. For the meta-analysis, we used Distiller SR to organize and retrieve the articles. Out of 2424 articles, 37 articles were eligible for meta-analysis but only 6 studies were included in the meta-analysis due to the unavailability of the dataset from other authors. Metaprop command in Stata 16 was used to calculate age- and sex-specific COPD prevalence from included articles for meta-analysis. Results: Japan has a lower age-adjusted COPD mortality rate than the US in both sexes over the past 30 years. From the meta-analysis, we found that COPD prevalence in Japan is lower than in the US in both sexes. Conclusion: Japan and the US are both developed countries and they both have upgraded guidelines and national plans for COPD prevention and management. COPD is a preventable disease but to lower the prevalence and mortality, it is essential to navigate factors such as socio-economic conditions, genetics, nutrition, health care coverage, affordability, and accessibility of healthcare servic

Background: Chronic Obstructive Pulmonary Disease (COPD) is considered to be a global health problem because of its higher prevalence and mortality rate. Multiple co-morbidities are associated with COPD including lung cancer, anemia, osteoporosis, coronary artery disease, renal dysfunction, diabetes, etc. It is a progressive disease that is particularly common among the elderly age group. Due to the growing number of aging populations worldwide, COPD cases are predicted to rise further. Objectives: The objective of our study is to calculate the age- and sex-specific COPD mortality rate and smoking rate in Japan and compared them to the US. In addition, we also aim to do a meta-analysis of COPD prevalence in Japan and compare it to the US. Methods: We extracted the COPD mortality and smoking dataset for Japan and the US from WHO (World health Organization) database and CDC (Center for Disease Control and Prevention) WONDER ( Wide-Ranging online data for Epidemiologic Research) database. For the meta-analysis, we used Distiller SR to organize and retrieve the articles. Out of 2424 articles, 37 articles were eligible for meta-analysis but only 6 studies were included in the meta-analysis due to the unavailability of the dataset from other authors. Metaprop command in Stata 16 was used to calculate age- and sex-specific COPD prevalence from included articles for meta-analysis. Results: Japan has a lower age-adjusted COPD mortality rate than the US in both sexes over the past 30 years. From the meta-analysis, we found that COPD prevalence in Japan is lower than in the US in both sexes. Conclusion: Japan and the US are both developed countries and they both have upgraded guidelines and national plans for COPD prevention and management. COPD is a preventable disease but to lower the prevalence and mortality, it is essential to navigate factors such as socio-economic conditions, genetics, nutrition, health care coverage, affordability, and accessibility of healthcare servic