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Selenocysteine, the 21st amino acid, has been found in 25 human selenoproteins and selenoenzymes important for fundamental cellular processes ranging from selenium homeostasis maintenance to the regulation of the overall metabolic rate. In all organisms that contain selenocysteine, both the synthesis of selenocysteine and its incorporation into a selenoprotein requires an elaborate synthetic and translational apparatus, which does not resemble the canonical enzymatic system employed for the 20 standard amino acids. In humans, three synthetic enzymes, a specialized elongation factor, an accessory protein factor, two catabolic enzymes, a tRNA, and a stem-loop structure in the selenoprotein mRNA are critical for ensuring that only selenocysteine is attached to selenocysteine tRNA and that only selenocysteine is inserted into the nascent polypeptide in response to a context-dependent UGA codon. The abnormal selenium homeostasis and mutations in selenoprotein genes have been causatively linked to a variety of human diseases, which, in turn, sparked a renewed interest in utilizing selenium as the dietary supplement to either prevent or remedy pathologic conditions. In contrast, the importance of the components of the selenocysteine-synthetic machinery for human health is less clear. Emerging evidence suggests that enzymes responsible for selenocysteine formation and decoding the selenocysteine UGA codon, which by extension are critical for synthesis of the entire selenoproteome, are essential for the development and health of the human organism.

Selenocysteine, the 21st amino acid, has been found in 25 human selenoproteins and selenoenzymes important for fundamental cellular processes ranging from selenium homeostasis maintenance to the regulation of the overall metabolic rate. In all organisms that contain selenocysteine, both the synthesis of selenocysteine and its incorporation into a selenoprotein requires an elaborate synthetic and translational apparatus, which does not resemble the canonical enzymatic system employed for the 20 standard amino acids. In humans, three synthetic enzymes, a specialized elongation factor, an accessory protein factor, two catabolic enzymes, a tRNA, and a stem-loop structure in the selenoprotein mRNA are critical for ensuring that only selenocysteine is attached to selenocysteine tRNA and that only selenocysteine is inserted into the nascent polypeptide in response to a context-dependent UGA codon. The abnormal selenium homeostasis and mutations in selenoprotein genes have been causatively linked to a variety of human diseases, which, in turn, sparked a renewed interest in utilizing selenium as the dietary supplement to either prevent or remedy pathologic conditions. In contrast, the importance of the components of the selenocysteine-synthetic machinery for human health is less clear. Emerging evidence suggests that enzymes responsible for selenocysteine formation and decoding the selenocysteine UGA codon, which by extension are critical for synthesis of the entire selenoproteome, are essential for the development and health of the human organism.

International Computer Music Conference Proceedings: vol. 1985, (dlps) bbp2372.1985.055, http://hdl.handle.net/2027/spo.bbp2372.1985.055, This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. Please contact mpub-help@umich.edu to use this work in a way not covered by the license.

International Computer Music Conference Proceedings: vol. 1986, (dlps) bbp2372.1986.027, http://hdl.handle.net/2027/spo.bbp2372.1986.027, This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. Please contact mpub-help@umich.edu to use this work in a way not covered by the license.

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Fungi, http://name.umdl.umich.edu/IC-HERB00IC-X-204002%5DMICH-F-204002_1, https://quod.lib.umich.edu/cgi/i/image/api/thumb/herb00ic/204002/MICH-F-204002_1/!250,250, The University of Michigan Library provides access to these materials for educational and research purposes. Some materials may be protected by copyright. If you decide to use any of these materials, you are responsible for making your own legal assessment and securing any necessary permission. If you have questions about the collection, please contact the Herbarium professional staff: herb-dlps-help@umich.edu. If you have concerns about the inclusion of an item in this collection, please contact Library Information Technology: libraryit-info@umich.edu., https://www.lib.umich.edu/about-us/policies/copyright-policy

An intimate profile of one of the most popular American singers of the 20th century, this first full-length biography of Karen Carpenter details every aspect of her life, from her modest Connecticut upbringing and her rise to stardom in southern California to the real story of her tragic, untimely death. This illuminating depiction of a 1970s icon covers her time as lead singer of the Carpenters—the top-selling American musical act of the decade—and provides insight into their string of 16 consecutive top-20 hits, including "Close to You," "We've Only Just Begun," "Top of the World," and "Superstar," as well as a critical review of her aborted solo career.A behind-the-scenes look into the life of a superstar, from the prolific recordings and the relentless touring to the awards, fame, and fortune, this history also chronicles her struggle with anorexia nervosa and gives important new details from her autopsy that shed new light on her death at age 32. Groups such as Sonic Youth and the Corrs and artists including k. d. lang and Madonna have cited Karen Carpenter among their major influences, and this definitive biography, based on exclusive interviews with nearly 100 of her friends and associates, is a testament to her brief yet remarkable life.

With a string of number-one hits showcasing Karen Carpenter's warm and distinctive vocals and Richard Carpenter's sophisticated compositions and arrangements, the Carpenters were responsible for some of the most popular music of the 1970s, and this compendium collects more than 50 articles, interviews, essays, reviews, and reassessments that chronicle the lives and career of this brother-sister musical team. Writings from pop journalists and historians such as Daniel J. Levitin, John Tobler, Digby Diehl, Ray Coleman, Robert Hilburn, and Lester Bangs provide insight into the music and personalities of the duo who produced such timeless pop music. From serious musical analyses of the Carpenters' arrangements to lighter pieces in which Karen and Richard discuss dating, cars, and high school, this new edition has been revised and expanded to include nearly a dozen additional pieces, some of which have never been published.

“It's going to be one hell of a great—everlastingly great—book with humor, tears, fun, emotion, and love,” Judy Garland said of her plans to tell her life story. But she died at the age of forty-seven before seeing it through. Judy Garland on Judy Garland is the closest we will likely come to experiencing and exploring the legend's abandoned autobiography. Collecting and presenting the most important Garland interviews and encounters that took place between 1935 and 1969, this work opens with her first radio appearance under contract with Metro-Goldwyn-Mayer and concludes with her last known interview, one taped for Radio Denmark just months before her death. What makes this collection unique and distinguishes it from the plethora of Garland biographies is that it places Judy in the role of storyteller. She wrote a number of essays for various publications and sat for countless print, radio, and television interviews. These and the other autobiographical efforts she made are proof that Judy Garland wanted her story told, and wanted it told in her own words. Finally, here it is.

"Nobody knows Dolly like Dolly," declares Dolly Parton. Dolly's is a rags-to-riches tale like no other. A dirt-poor Smoky Mountain childhood paved the way for the buxom blonde butterfly's metamorphosis from singer-songwriter to international music superstar. The undisputed "Queen of Country Music," Dolly has sold more than 100 million records worldwide and has conquered just about every facet of the entertainment industry: music, film, television, publishing, theater, and even theme parks. It has been more than fifty years since Dolly Parton arrived in Nashville with just her guitar and a dream. Her story has been told many times and in many ways, but never like this. Dolly on Dolly is a collection of interviews spanning five decades of her career and featuring material gathered from celebrated publications including Rolling Stone, Cosmopolitan, Playboy, and Andy Warhol's Interview magazine. Also included are interviews which have not been previously available in print. Dolly's feisty and irresistible brand of humor, combined with her playful, pull-up-a-chair-and-stay-awhile delivery, makes for a fascinating and inviting experience in down-home philosophy and storytelling. Much like her patchwork "Coat of Many Colors," this book harkens back to the legendary entertainer's roots and traces her evolution, stitching it all together one piece at a time.

An intimate profile of one of the most popular American singers of the 20th century, this first full-length biography of Karen Carpenter details every aspect of her life, from her modest Connecticut upbringing and her rise to stardom in southern California to the real story of her tragic, untimely death. This illuminating depiction of a 1970s icon covers her time as lead singer of the Carpenters—the top-selling American musical act of the decade—and provides insight into their string of 16 consecutive top-20 hits, including "Close to You," "We've Only Just Begun," "Top of the World," and "Superstar," as well as a critical review of her aborted solo career.A behind-the-scenes look into the life of a superstar, from the prolific recordings and the relentless touring to the awards, fame, and fortune, this history also chronicles her struggle with anorexia nervosa and gives important new details from her autopsy that shed new light on her death at age 32. Groups such as Sonic Youth and the Corrs and artists including k. d. lang and Madonna have cited Karen Carpenter among their major influences, and this definitive biography, based on exclusive interviews with nearly 100 of her friends and associates, is a testament to her brief yet remarkable life.

With a string of number-one hits showcasing Karen Carpenter's warm and distinctive vocals and Richard Carpenter's sophisticated compositions and arrangements, the Carpenters were responsible for some of the most popular music of the 1970s, and this compendium collects more than 50 articles, interviews, essays, reviews, and reassessments that chronicle the lives and career of this brother-sister musical team. Writings from pop journalists and historians such as Daniel J. Levitin, John Tobler, Digby Diehl, Ray Coleman, Robert Hilburn, and Lester Bangs provide insight into the music and personalities of the duo who produced such timeless pop music. From serious musical analyses of the Carpenters' arrangements to lighter pieces in which Karen and Richard discuss dating, cars, and high school, this new edition has been revised and expanded to include nearly a dozen additional pieces, some of which have never been published.

“It's going to be one hell of a great—everlastingly great—book with humor, tears, fun, emotion, and love,” Judy Garland said of her plans to tell her life story. But she died at the age of forty-seven before seeing it through. Judy Garland on Judy Garland is the closest we will likely come to experiencing and exploring the legend's abandoned autobiography. Collecting and presenting the most important Garland interviews and encounters that took place between 1935 and 1969, this work opens with her first radio appearance under contract with Metro-Goldwyn-Mayer and concludes with her last known interview, one taped for Radio Denmark just months before her death. What makes this collection unique and distinguishes it from the plethora of Garland biographies is that it places Judy in the role of storyteller. She wrote a number of essays for various publications and sat for countless print, radio, and television interviews. These and the other autobiographical efforts she made are proof that Judy Garland wanted her story told, and wanted it told in her own words. Finally, here it is.

"Nobody knows Dolly like Dolly," declares Dolly Parton. Dolly's is a rags-to-riches tale like no other. A dirt-poor Smoky Mountain childhood paved the way for the buxom blonde butterfly's metamorphosis from singer-songwriter to international music superstar. The undisputed "Queen of Country Music," Dolly has sold more than 100 million records worldwide and has conquered just about every facet of the entertainment industry: music, film, television, publishing, theater, and even theme parks. It has been more than fifty years since Dolly Parton arrived in Nashville with just her guitar and a dream. Her story has been told many times and in many ways, but never like this. Dolly on Dolly is a collection of interviews spanning five decades of her career and featuring material gathered from celebrated publications including Rolling Stone, Cosmopolitan, Playboy, and Andy Warhol's Interview magazine. Also included are interviews which have not been previously available in print. Dolly's feisty and irresistible brand of humor, combined with her playful, pull-up-a-chair-and-stay-awhile delivery, makes for a fascinating and inviting experience in down-home philosophy and storytelling. Much like her patchwork "Coat of Many Colors," this book harkens back to the legendary entertainer's roots and traces her evolution, stitching it all together one piece at a time.

An intimate profile of one of the most popular American singers of the 20th century, this first full-length biography of Karen Carpenter details every aspect of her life, from her modest Connecticut upbringing and her rise to stardom in southern California to the real story of her tragic, untimely death. This illuminating depiction of a 1970s icon covers her time as lead singer of the Carpenters—the top-selling American musical act of the decade—and provides insight into their string of 16 consecutive top-20 hits, including "Close to You," "We've Only Just Begun," "Top of the World," and "Superstar," as well as a critical review of her aborted solo career.A behind-the-scenes look into the life of a superstar, from the prolific recordings and the relentless touring to the awards, fame, and fortune, this history also chronicles her struggle with anorexia nervosa and gives important new details from her autopsy that shed new light on her death at age 32. Groups such as Sonic Youth and the Corrs and artists including k. d. lang and Madonna have cited Karen Carpenter among their major influences, and this definitive biography, based on exclusive interviews with nearly 100 of her friends and associates, is a testament to her brief yet remarkable life.

With a string of number-one hits showcasing Karen Carpenter's warm and distinctive vocals and Richard Carpenter's sophisticated compositions and arrangements, the Carpenters were responsible for some of the most popular music of the 1970s, and this compendium collects more than 50 articles, interviews, essays, reviews, and reassessments that chronicle the lives and career of this brother-sister musical team. Writings from pop journalists and historians such as Daniel J. Levitin, John Tobler, Digby Diehl, Ray Coleman, Robert Hilburn, and Lester Bangs provide insight into the music and personalities of the duo who produced such timeless pop music. From serious musical analyses of the Carpenters' arrangements to lighter pieces in which Karen and Richard discuss dating, cars, and high school, this new edition has been revised and expanded to include nearly a dozen additional pieces, some of which have never been published.

“It's going to be one hell of a great—everlastingly great—book with humor, tears, fun, emotion, and love,” Judy Garland said of her plans to tell her life story. But she died at the age of forty-seven before seeing it through. Judy Garland on Judy Garland is the closest we will likely come to experiencing and exploring the legend's abandoned autobiography. Collecting and presenting the most important Garland interviews and encounters that took place between 1935 and 1969, this work opens with her first radio appearance under contract with Metro-Goldwyn-Mayer and concludes with her last known interview, one taped for Radio Denmark just months before her death. What makes this collection unique and distinguishes it from the plethora of Garland biographies is that it places Judy in the role of storyteller. She wrote a number of essays for various publications and sat for countless print, radio, and television interviews. These and the other autobiographical efforts she made are proof that Judy Garland wanted her story told, and wanted it told in her own words. Finally, here it is.

"Nobody knows Dolly like Dolly," declares Dolly Parton. Dolly's is a rags-to-riches tale like no other. A dirt-poor Smoky Mountain childhood paved the way for the buxom blonde butterfly's metamorphosis from singer-songwriter to international music superstar. The undisputed "Queen of Country Music," Dolly has sold more than 100 million records worldwide and has conquered just about every facet of the entertainment industry: music, film, television, publishing, theater, and even theme parks. It has been more than fifty years since Dolly Parton arrived in Nashville with just her guitar and a dream. Her story has been told many times and in many ways, but never like this. Dolly on Dolly is a collection of interviews spanning five decades of her career and featuring material gathered from celebrated publications including Rolling Stone, Cosmopolitan, Playboy, and Andy Warhol's Interview magazine. Also included are interviews which have not been previously available in print. Dolly's feisty and irresistible brand of humor, combined with her playful, pull-up-a-chair-and-stay-awhile delivery, makes for a fascinating and inviting experience in down-home philosophy and storytelling. Much like her patchwork "Coat of Many Colors," this book harkens back to the legendary entertainer's roots and traces her evolution, stitching it all together one piece at a time.

An intimate profile of one of the most popular American singers of the 20th century, this first full-length biography of Karen Carpenter details every aspect of her life, from her modest Connecticut upbringing and her rise to stardom in southern California to the real story of her tragic, untimely death. This illuminating depiction of a 1970s icon covers her time as lead singer of the Carpenters—the top-selling American musical act of the decade—and provides insight into their string of 16 consecutive top-20 hits, including "Close to You," "We've Only Just Begun," "Top of the World," and "Superstar," as well as a critical review of her aborted solo career.A behind-the-scenes look into the life of a superstar, from the prolific recordings and the relentless touring to the awards, fame, and fortune, this history also chronicles her struggle with anorexia nervosa and gives important new details from her autopsy that shed new light on her death at age 32. Groups such as Sonic Youth and the Corrs and artists including k. d. lang and Madonna have cited Karen Carpenter among their major influences, and this definitive biography, based on exclusive interviews with nearly 100 of her friends and associates, is a testament to her brief yet remarkable life.

With a string of number-one hits showcasing Karen Carpenter's warm and distinctive vocals and Richard Carpenter's sophisticated compositions and arrangements, the Carpenters were responsible for some of the most popular music of the 1970s, and this compendium collects more than 50 articles, interviews, essays, reviews, and reassessments that chronicle the lives and career of this brother-sister musical team. Writings from pop journalists and historians such as Daniel J. Levitin, John Tobler, Digby Diehl, Ray Coleman, Robert Hilburn, and Lester Bangs provide insight into the music and personalities of the duo who produced such timeless pop music. From serious musical analyses of the Carpenters' arrangements to lighter pieces in which Karen and Richard discuss dating, cars, and high school, this new edition has been revised and expanded to include nearly a dozen additional pieces, some of which have never been published.

“It's going to be one hell of a great—everlastingly great—book with humor, tears, fun, emotion, and love,” Judy Garland said of her plans to tell her life story. But she died at the age of forty-seven before seeing it through. Judy Garland on Judy Garland is the closest we will likely come to experiencing and exploring the legend's abandoned autobiography. Collecting and presenting the most important Garland interviews and encounters that took place between 1935 and 1969, this work opens with her first radio appearance under contract with Metro-Goldwyn-Mayer and concludes with her last known interview, one taped for Radio Denmark just months before her death. What makes this collection unique and distinguishes it from the plethora of Garland biographies is that it places Judy in the role of storyteller. She wrote a number of essays for various publications and sat for countless print, radio, and television interviews. These and the other autobiographical efforts she made are proof that Judy Garland wanted her story told, and wanted it told in her own words. Finally, here it is.

"Nobody knows Dolly like Dolly," declares Dolly Parton. Dolly's is a rags-to-riches tale like no other. A dirt-poor Smoky Mountain childhood paved the way for the buxom blonde butterfly's metamorphosis from singer-songwriter to international music superstar. The undisputed "Queen of Country Music," Dolly has sold more than 100 million records worldwide and has conquered just about every facet of the entertainment industry: music, film, television, publishing, theater, and even theme parks. It has been more than fifty years since Dolly Parton arrived in Nashville with just her guitar and a dream. Her story has been told many times and in many ways, but never like this. Dolly on Dolly is a collection of interviews spanning five decades of her career and featuring material gathered from celebrated publications including Rolling Stone, Cosmopolitan, Playboy, and Andy Warhol's Interview magazine. Also included are interviews which have not been previously available in print. Dolly's feisty and irresistible brand of humor, combined with her playful, pull-up-a-chair-and-stay-awhile delivery, makes for a fascinating and inviting experience in down-home philosophy and storytelling. Much like her patchwork "Coat of Many Colors," this book harkens back to the legendary entertainer's roots and traces her evolution, stitching it all together one piece at a time.

The third of Judy Garland's five husbands, Sid Luft was the one man in her life who stuck around. He was chiefly responsible for the final act of Judy's meteoric comeback after she was unceremoniously booted off the MGM lot: he produced her iconic, Oscar-nominated vehicle A Star Is Born and expertly shaped her concert career. Previously unpublished, Sid Luft's intimate autobiography tells his and Judy's story in hard-boiled yet elegant prose. It begins on a fateful night in New York City when the not quite divorced Judy Garland and the not quite divorced Sid Luft meet at Billy Reed's Little Club and fall for each other. The romance lasted Judy's lifetime, despite the separations, the reconciliations, and the divorce. Under Luft's management, Judy came back bigger than ever, building a singing career that rivaled Sinatra's. However, her drug dependencies and suicidal tendencies put a tremendous strain on the relationship. Sid did not complete his memoir; it ended in 1960 after Judy hired David Begelman and Freddie Fields to manage her career. But Randy L. Schmidt, acclaimed editor of Judy Garland on Judy Garland and author of Little Girl Blue: The Life of Karen Carpenter, seamlessly pieced together the final section of the book from extensive interviews with Sid, most previously unpublished. Despite everything, Sid never stopped loving Judy and never forgave himself for not being able to ultimately save her from the demons that drove her to an early death at age forty-seven in 1969. Sid served as chief conservator of the Garland legacy until his death at the age of eighty-nine in 2005. This is his testament to the love of his life.

The third of Judy Garland's five husbands, Sid Luft was the one man in her life who stuck around. He was chiefly responsible for the final act of Judy's meteoric comeback after she was unceremoniously booted off the MGM lot: he produced her iconic, Oscar-nominated vehicle A Star Is Born and expertly shaped her concert career. Previously unpublished, Sid Luft's intimate autobiography tells his and Judy's story in hard-boiled yet elegant prose. It begins on a fateful night in New York City when the not quite divorced Judy Garland and the not quite divorced Sid Luft meet at Billy Reed's Little Club and fall for each other. The romance lasted Judy's lifetime, despite the separations, the reconciliations, and the divorce. Under Luft's management, Judy came back bigger than ever, building a singing career that rivaled Sinatra's. However, her drug dependencies and suicidal tendencies put a tremendous strain on the relationship. Sid did not complete his memoir; it ended in 1960 after Judy hired David Begelman and Freddie Fields to manage her career. But Randy L. Schmidt, acclaimed editor of Judy Garland on Judy Garland and author of Little Girl Blue: The Life of Karen Carpenter, seamlessly pieced together the final section of the book from extensive interviews with Sid, most previously unpublished. Despite everything, Sid never stopped loving Judy and never forgave himself for not being able to ultimately save her from the demons that drove her to an early death at age forty-seven in 1969. Sid served as chief conservator of the Garland legacy until his death at the age of eighty-nine in 2005. This is his testament to the love of his life.

The third of Judy Garland's five husbands, Sid Luft was the one man in her life who stuck around. He was chiefly responsible for the final act of Judy's meteoric comeback after she was unceremoniously booted off the MGM lot: he produced her iconic, Oscar-nominated vehicle A Star Is Born and expertly shaped her concert career. Previously unpublished, Sid Luft's intimate autobiography tells his and Judy's story in hard-boiled yet elegant prose. It begins on a fateful night in New York City when the not quite divorced Judy Garland and the not quite divorced Sid Luft meet at Billy Reed's Little Club and fall for each other. The romance lasted Judy's lifetime, despite the separations, the reconciliations, and the divorce. Under Luft's management, Judy came back bigger than ever, building a singing career that rivaled Sinatra's. However, her drug dependencies and suicidal tendencies put a tremendous strain on the relationship. Sid did not complete his memoir; it ended in 1960 after Judy hired David Begelman and Freddie Fields to manage her career. But Randy L. Schmidt, acclaimed editor of Judy Garland on Judy Garland and author of Little Girl Blue: The Life of Karen Carpenter, seamlessly pieced together the final section of the book from extensive interviews with Sid, most previously unpublished. Despite everything, Sid never stopped loving Judy and never forgave himself for not being able to ultimately save her from the demons that drove her to an early death at age forty-seven in 1969. Sid served as chief conservator of the Garland legacy until his death at the age of eighty-nine in 2005. This is his testament to the love of his life.

The third of Judy Garland's five husbands, Sid Luft was the one man in her life who stuck around. He was chiefly responsible for the final act of Judy's meteoric comeback after she was unceremoniously booted off the MGM lot: he produced her iconic, Oscar-nominated vehicle A Star Is Born and expertly shaped her concert career. Previously unpublished, Sid Luft's intimate autobiography tells his and Judy's story in hard-boiled yet elegant prose. It begins on a fateful night in New York City when the not quite divorced Judy Garland and the not quite divorced Sid Luft meet at Billy Reed's Little Club and fall for each other. The romance lasted Judy's lifetime, despite the separations, the reconciliations, and the divorce. Under Luft's management, Judy came back bigger than ever, building a singing career that rivaled Sinatra's. However, her drug dependencies and suicidal tendencies put a tremendous strain on the relationship. Sid did not complete his memoir; it ended in 1960 after Judy hired David Begelman and Freddie Fields to manage her career. But Randy L. Schmidt, acclaimed editor of Judy Garland on Judy Garland and author of Little Girl Blue: The Life of Karen Carpenter, seamlessly pieced together the final section of the book from extensive interviews with Sid, most previously unpublished. Despite everything, Sid never stopped loving Judy and never forgave himself for not being able to ultimately save her from the demons that drove her to an early death at age forty-seven in 1969. Sid served as chief conservator of the Garland legacy until his death at the age of eighty-nine in 2005. This is his testament to the love of his life.