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We analyzed the transverse momentum spectra of positively and negatively charged pions ($\pi^+$ and $\pi^-$), positively and negatively charged kaons ($K^+$ and $K^-$), protons and antiprotons ($p$ and $\bar p$), as well as $\phi$ produced in mid-(pseudo)rapidity region in central nucleus--nucleus (AA) collisions over a center-of-mass energy range from 2.16 to 2760 GeV per nucleon pair. The transverse momentum of the considered particle is regarded as the joint contribution of two participant partons which obey the modified Tsallis-like transverse momentum distribution and have random azimuths in superposition. The calculation of transverse momentum distribution of particles is performed by the Monte Carlo method and compared with the experimental data measured by international collaborations. The excitation functions of effective temperature and other parameters are obtained in the considered energy range. With the increase of collision energy, the effective temperature parameter increases quickly and then slowly. The boundary appears at around 5 GeV, which means the change of reaction mechanism and/or generated matter., Comment: 15 pages,5 figures

We analyzed the transverse momentum spectra of positively and negatively charged pions ($\pi^+$ and $\pi^-$), positively and negatively charged kaons ($K^+$ and $K^-$), protons and antiprotons ($p$ and $\bar p$), as well as $\phi$ produced in mid-(pseudo)rapidity region in central nucleus--nucleus (AA) collisions over a center-of-mass energy range from 2.16 to 2760 GeV per nucleon pair. The transverse momentum of the considered particle is regarded as the joint contribution of two participant partons which obey the modified Tsallis-like transverse momentum distribution and have random azimuths in superposition. The calculation of transverse momentum distribution of particles is performed by the Monte Carlo method and compared with the experimental data measured by international collaborations. The excitation functions of effective temperature and other parameters are obtained in the considered energy range. With the increase of collision energy, the effective temperature parameter increases quickly and then slowly. The boundary appears at around 5 GeV, which means the change of reaction mechanism and/or generated matter., Comment: 15 pages,5 figures

We analyzed the transverse momentum spectra of positively and negatively charged pions ($\pi^+$ and $\pi^-$), positively and negatively charged kaons ($K^+$ and $K^-$), protons and antiprotons ($p$ and $\bar p$), as well as $\phi$ produced in mid-(pseudo)rapidity region in central nucleus--nucleus (AA) collisions over a center-of-mass energy range from 2.16 to 2760 GeV per nucleon pair. The transverse momentum of the considered particle is regarded as the joint contribution of two participant partons which obey the modified Tsallis-like transverse momentum distribution and have random azimuths in superposition. The calculation of transverse momentum distribution of particles is performed by the Monte Carlo method and compared with the experimental data measured by international collaborations. The excitation functions of effective temperature and other parameters are obtained in the considered energy range. With the increase of collision energy, the effective temperature parameter increases quickly and then slowly. The boundary appears at around 5 GeV, which means the change of reaction mechanism and/or generated matter., Comment: 15 pages,5 figures

Background: Nitric oxide synthase 1 adaptor protein (NOS1AP; previously named CAPON) is linked to the glutamatergic postsynaptic density through interaction with neuronal nitric oxide synthase (nNOS). NOS1AP and its interaction with nNOS have been associated with several mental disorders. Despite the high levels of NOS1AP expression in the hippocampus and the relevance of this brain region in glutamatergic signalling as well as mental disorders, a potential role of hippocampal NOS1AP in the pathophysiology of these disorders has not been investigated yet. Methods: To uncover the function of NOS1AP in hippocampus, we made use of recombinant adeno-associated viruses to overexpress murine full-length NOS1AP or the NOS1AP carboxyterminus in the hippocampus of mice. We investigated these mice for changes in gene expression, neuronal morphology, and relevant behavioural phenotypes. Findings: We found that hippocampal overexpression of NOS1AP markedly increased the interaction of nNOS with PSD-95, reduced dendritic spine density, and changed dendritic spine morphology at CA1 synapses. At the behavioural level, we observed an impairment in social memory and decreased spatial working memory capacity. Interpretation: Our data provide a mechanistic explanation for a highly selective and specific contribution of hippocampal NOS1AP and its interaction with the glutamatergic postsynaptic density to cross-disorder pathophysiology. Our findings allude to therapeutic relevance due to the druggability of this molecule. Funding: This study was funded in part by the DFG, the BMBF, the Academy of Finland, the NIH, the Japanese Society of Clinical Neuropsychopharmacology, the Ministry of Education of the Russian Federation, and the European Community.

Background: Nitric oxide synthase 1 adaptor protein (NOS1AP; previously named CAPON) is linked to the glutamatergic postsynaptic density through interaction with neuronal nitric oxide synthase (nNOS). NOS1AP and its interaction with nNOS have been associated with several mental disorders. Despite the high levels of NOS1AP expression in the hippocampus and the relevance of this brain region in glutamatergic signalling as well as mental disorders, a potential role of hippocampal NOS1AP in the pathophysiology of these disorders has not been investigated yet. Methods: To uncover the function of NOS1AP in hippocampus, we made use of recombinant adeno-associated viruses to overexpress murine full-length NOS1AP or the NOS1AP carboxyterminus in the hippocampus of mice. We investigated these mice for changes in gene expression, neuronal morphology, and relevant behavioural phenotypes. Findings: We found that hippocampal overexpression of NOS1AP markedly increased the interaction of nNOS with PSD-95, reduced dendritic spine density, and changed dendritic spine morphology at CA1 synapses. At the behavioural level, we observed an impairment in social memory and decreased spatial working memory capacity. Interpretation: Our data provide a mechanistic explanation for a highly selective and specific contribution of hippocampal NOS1AP and its interaction with the glutamatergic postsynaptic density to cross-disorder pathophysiology. Our findings allude to therapeutic relevance due to the druggability of this molecule. Funding: This study was funded in part by the DFG, the BMBF, the Academy of Finland, the NIH, the Japanese Society of Clinical Neuropsychopharmacology, the Ministry of Education of the Russian Federation, and the European Community.

Background: Nitric oxide synthase 1 adaptor protein (NOS1AP; previously named CAPON) is linked to the glutamatergic postsynaptic density through interaction with neuronal nitric oxide synthase (nNOS). NOS1AP and its interaction with nNOS have been associated with several mental disorders. Despite the high levels of NOS1AP expression in the hippocampus and the relevance of this brain region in glutamatergic signalling as well as mental disorders, a potential role of hippocampal NOS1AP in the pathophysiology of these disorders has not been investigated yet. Methods: To uncover the function of NOS1AP in hippocampus, we made use of recombinant adeno-associated viruses to overexpress murine full-length NOS1AP or the NOS1AP carboxyterminus in the hippocampus of mice. We investigated these mice for changes in gene expression, neuronal morphology, and relevant behavioural phenotypes. Findings: We found that hippocampal overexpression of NOS1AP markedly increased the interaction of nNOS with PSD-95, reduced dendritic spine density, and changed dendritic spine morphology at CA1 synapses. At the behavioural level, we observed an impairment in social memory and decreased spatial working memory capacity. Interpretation: Our data provide a mechanistic explanation for a highly selective and specific contribution of hippocampal NOS1AP and its interaction with the glutamatergic postsynaptic density to cross-disorder pathophysiology. Our findings allude to therapeutic relevance due to the druggability of this molecule.

The transverse momentum spectra of charged pions, kaons, and protons produced at mid-rapidity in central nucleus-nucleus (AA) collisions at high energies are analyzed by considering particles to be created from two participant partons which are assumed to be contributors from the collision system. Each participant (contributor) parton is assumed to contribute to the transverse momentum by a Tsallis-like function. The contributions of the two participant partons are regarded as the two components of transverse momentum of the identified particle. The experimental data measured in high-energy AA collisions by international collaborations are studied. The excitation functions of kinetic freeze-out temperature and transverse flow velocity are extracted. The two parameters increase quickly from $\approx3$ to $\approx10$ GeV (exactly from 2.7 to 7.7 GeV) and then slowly at above 10 GeV with the increase of collision energy. In particular, there is a plateau from near 10 GeV to 200 GeV in the excitation function of kinetic freeze-out temperature., Comment: 22 pages, 7 figures. Special Issue "Hydrodynamics and Thermodynamics in High Energy Physics" in Entropy, accepted

The transverse momentum spectra of different types of particles produced in central and peripheral gold-gold (Au-Au) and (inelastic) proton-proton ($pp$) collisions at the Relativistic Heavy Ion Collider (RHIC), as well as in central and peripheral lead-lead (Pb-Pb) and $pp$ collisions at the Large Hadron Collider (LHC) are analyzed by the standard distribution in terms of multi-component. The obtained results from the standard distribution give an approximate agreement with the measured experimental data by the STAR, PHENIX and ALICE Collaborations. The methodical behavior of the effective (kinetic freeze-out) temperature, transverse flow velocity and kinetic freeze-out volume with the mass dependence for different particles is obtained, which observes the early kinetic freeze-out of heavier particles as compared to the lighter particles. The parameters for emissions of different particles are observed to be different, which reveals a direct signature of the mass dependent differential kinetic freeze-out. It is also observed that the peripheral nucleus-nucleus ($AA$) and $pp$ collisions at the same center-of-mass energy per nucleon pair are close in terms of the extracted parameters., Comment: 16 pages, 6 figures. Nuclear Science and Techniques, accepted

The transverse momentum spectra of charged pions, kaons, and protons produced at mid-rapidity in central nucleus-nucleus (AA) collisions at high energies are analyzed by considering particles to be created from two participant partons which are assumed to be contributors from the collision system. Each participant (contributor) parton is assumed to contribute to the transverse momentum by a Tsallis-like function. The contributions of the two participant partons are regarded as the two components of transverse momentum of the identified particle. The experimental data measured in high-energy AA collisions by international collaborations are studied. The excitation functions of kinetic freeze-out temperature and transverse flow velocity are extracted. The two parameters increase quickly from $\approx3$ to $\approx10$ GeV (exactly from 2.7 to 7.7 GeV) and then slowly at above 10 GeV with the increase of collision energy. In particular, there is a plateau from near 10 GeV to 200 GeV in the excitation function of kinetic freeze-out temperature., Comment: 22 pages, 7 figures. Special Issue "Hydrodynamics and Thermodynamics in High Energy Physics" in Entropy, accepted

The transverse momentum spectra of charged pions, kaons, and protons produced at mid-rapidity in central nucleus-nucleus (AA) collisions at high energies are analyzed by considering particles to be created from two participant partons which are assumed to be contributors from the collision system. Each participant (contributor) parton is assumed to contribute to the transverse momentum by a Tsallis-like function. The contributions of the two participant partons are regarded as the two components of transverse momentum of the identified particle. The experimental data measured in high-energy AA collisions by international collaborations are studied. The excitation functions of kinetic freeze-out temperature and transverse flow velocity are extracted. The two parameters increase quickly from $\approx3$ to $\approx10$ GeV (exactly from 2.7 to 7.7 GeV) and then slowly at above 10 GeV with the increase of collision energy. In particular, there is a plateau from near 10 GeV to 200 GeV in the excitation function of kinetic freeze-out temperature., Comment: 22 pages, 7 figures. Special Issue "Hydrodynamics and Thermodynamics in High Energy Physics" in Entropy, accepted

The transverse momentum spectra of different types of particles produced in central and peripheral gold-gold (Au-Au) and (inelastic) proton-proton ($pp$) collisions at the Relativistic Heavy Ion Collider (RHIC), as well as in central and peripheral lead-lead (Pb-Pb) and $pp$ collisions at the Large Hadron Collider (LHC) are analyzed by the standard distribution in terms of multi-component. The obtained results from the standard distribution give an approximate agreement with the measured experimental data by the STAR, PHENIX and ALICE Collaborations. The methodical behavior of the effective (kinetic freeze-out) temperature, transverse flow velocity and kinetic freeze-out volume with the mass dependence for different particles is obtained, which observes the early kinetic freeze-out of heavier particles as compared to the lighter particles. The parameters for emissions of different particles are observed to be different, which reveals a direct signature of the mass dependent differential kinetic freeze-out. It is also observed that the peripheral nucleus-nucleus ($AA$) and $pp$ collisions at the same center-of-mass energy per nucleon pair are close in terms of the extracted parameters., Comment: 16 pages, 6 figures. Nuclear Science and Techniques, accepted

Transverse momentum (mass) spectra of positively and negatively charged pions, positively and negatively charged kaons, protons and antiprotons produced at mid-(pseudo)rapidity in various collisions at high energies are analyzed in this work. The experimental data measured in central gold-gold, central lead-lead, and inelastic proton-proton collisions by several international collaborations are studied. The (two-component) standard distribution is used to fit the data and extract the excitation function of effective temperature. Then, the excitation functions of kinetic freeze-out temperature, transverse flow velocity, and initial temperature are obtained. In the considered collisions, the four parameters increase with the increase of collision energy in general, and the kinetic freeze-out temperature appears the trend of saturation at the top Relativistic Heavy Ion Collider and the Large Hadron Collider., Comment: 20 pages, 6 figures. Advances in High Energy Physics, accepted

Transverse momentum (mass) spectra of positively and negatively charged pions, positively and negatively charged kaons, protons and antiprotons produced at mid-(pseudo)rapidity in various collisions at high energies are analyzed in this work. The experimental data measured in central gold-gold, central lead-lead, and inelastic proton-proton collisions by several international collaborations are studied. The (two-component) standard distribution is used to fit the data and extract the excitation function of effective temperature. Then, the excitation functions of kinetic freeze-out temperature, transverse flow velocity, and initial temperature are obtained. In the considered collisions, the four parameters increase with the increase of collision energy in general, and the kinetic freeze-out temperature appears the trend of saturation at the top Relativistic Heavy Ion Collider and the Large Hadron Collider., Comment: 20 pages, 6 figures. Advances in High Energy Physics, accepted

Transverse momentum (mass) spectra of positively and negatively charged pions, positively and negatively charged kaons, protons and antiprotons produced at mid-(pseudo)rapidity in various collisions at high energies are analyzed in this work. The experimental data measured in central gold-gold, central lead-lead, and inelastic proton-proton collisions by several international collaborations are studied. The (two-component) standard distribution is used to fit the data and extract the excitation function of effective temperature. Then, the excitation functions of kinetic freeze-out temperature, transverse flow velocity, and initial temperature are obtained. In the considered collisions, the four parameters increase with the increase of collision energy in general, and the kinetic freeze-out temperature appears the trend of saturation at the top Relativistic Heavy Ion Collider and the Large Hadron Collider., Comment: 20 pages, 6 figures. Advances in High Energy Physics, accepted

Transverse momentum spectra of negative and positive pions produced at mid-(pseudo)rapidity in inelastic or non-single-diffractive proton-proton collisions and in central nucleus-nucleus collisions over an energy range from a few GeV to above 10 TeV are analyzed by a (two-component) blast-wave model with Boltzmann-Gibbs statistics and with Tsallis statistics respectively. The model results are in similarly well agreement with the experimental data measured by a few productive collaborations who work at the Heavy Ion Synchrotron (SIS), Super Proton Synchrotron (SPS), Relativistic Heavy Ion Collider (RHIC), and Large Hadron Collider (LHC), respectively. The energy dependent kinetic freeze-out temperature and transverse flow velocity are obtained and analyzed. Both the quantities have quick increase from the SIS to SPS, and slight increase or approximate invariability from the top RHIC to LHC. Around the energy bridge from the SPS to RHIC, the considered quantities in proton-proton collisions obtained by the blast-wave model with Boltzmann-Gibbs statistics show more complex energy dependent behavior comparing with the results in other three cases., Comment: Updated version, 16 pages, 4 figures. Only the first component is used to extract $T_0$ and $\beta_T$. Conclusions unchanged. arXiv admin note: text overlap with arXiv:1805.03342

Transverse momentum spectra of negative and positive pions produced at mid-(pseudo)rapidity in inelastic or non-single-diffractive proton-proton collisions over a center-of-mass energy, $\sqrt{s}$, range from a few GeV to above 10 TeV are analyzed by the blast-wave fit with Boltzmann (Tsallis) distribution. The blast-wave fit results are well fitting to the experimental data measured by several collaborations. In a particular superposition with Hagedorn function, both the excitation functions of kinetic freeze-out temperature ($T_0$) of emission source and transverse flow velocity ($\beta_T$) of produced particles obtained from a given selection in the blast-wave fit with Boltzmann distribution have a hill at $\sqrt{s}\approx10$ GeV, a drop at dozens of GeV, and then an increase from dozens of GeV to above 10 TeV. However, both the excitation functions of $T_0$ and $\beta_T$ obtained in the blast-wave fit with Tsallis distribution do not show such a complex structure, but a very low hill. In another selection for the parameters or in the superposition with the usual step function, $T_0$ and $\beta_T$ increase generally quickly from a few GeV to about 10 GeV and then slightly at above 10 GeV, there is no such the complex structure, when also studying nucleus-nucleus collisions., Comment: 24 pages, 8 figures. Invited contribution to the special issue "Statistical Approaches in High Energy Physics" in Physics, accepted

Transverse momentum spectra of negative and positive pions produced at mid-(pseudo)rapidity in inelastic or non-single-diffractive proton-proton collisions and in central nucleus-nucleus collisions over an energy range from a few GeV to above 10 TeV are analyzed by a (two-component) blast-wave model with Boltzmann-Gibbs statistics and with Tsallis statistics respectively. The model results are in similarly well agreement with the experimental data measured by a few productive collaborations who work at the Heavy Ion Synchrotron (SIS), Super Proton Synchrotron (SPS), Relativistic Heavy Ion Collider (RHIC), and Large Hadron Collider (LHC), respectively. The energy dependent kinetic freeze-out temperature and transverse flow velocity are obtained and analyzed. Both the quantities have quick increase from the SIS to SPS, and slight increase or approximate invariability from the top RHIC to LHC. Around the energy bridge from the SPS to RHIC, the considered quantities in proton-proton collisions obtained by the blast-wave model with Boltzmann-Gibbs statistics show more complex energy dependent behavior comparing with the results in other three cases., Comment: Updated version, 16 pages, 4 figures. Only the first component is used to extract $T_0$ and $\beta_T$. Conclusions unchanged. arXiv admin note: text overlap with arXiv:1805.03342

Transverse momentum spectra of negative and positive pions produced at mid-(pseudo)rapidity in inelastic or non-single-diffractive proton-proton collisions over a center-of-mass energy, $\sqrt{s}$, range from a few GeV to above 10 TeV are analyzed by the blast-wave fit with Boltzmann (Tsallis) distribution. The blast-wave fit results are well fitting to the experimental data measured by several collaborations. In a particular superposition with Hagedorn function, both the excitation functions of kinetic freeze-out temperature ($T_0$) of emission source and transverse flow velocity ($\beta_T$) of produced particles obtained from a given selection in the blast-wave fit with Boltzmann distribution have a hill at $\sqrt{s}\approx10$ GeV, a drop at dozens of GeV, and then an increase from dozens of GeV to above 10 TeV. However, both the excitation functions of $T_0$ and $\beta_T$ obtained in the blast-wave fit with Tsallis distribution do not show such a complex structure, but a very low hill. In another selection for the parameters or in the superposition with the usual step function, $T_0$ and $\beta_T$ increase generally quickly from a few GeV to about 10 GeV and then slightly at above 10 GeV, there is no such the complex structure, when also studying nucleus-nucleus collisions., Comment: 24 pages, 8 figures. Invited contribution to the special issue "Statistical Approaches in High Energy Physics" in Physics, accepted

This paper focuses on the problem of robust H∞ control for a class of switched non-linear systems with neutral uncertainties. The multiple Lyapunov function approach and the common Lyapunov function approach are exploited respectively for the cases whet

Gang Sun1, Min Li1, Li Li1, Guo-ying Li1, Zhi-wei Jing21Departments of Medical Imaging, 2Medical Statistics, Jinan Military General Hospital, Shandong Province, ChinaAbstract: The purpose of this study was to determine the optimal electrocardiographic (ECG) pulsing windows and evaluate the effect on reduced dose and accuracy using 320-detector rows dynamic volume computed tomography (DVCT). A total of 170 patients were prospectively studied. The optimal reconstruction windows were analyzed in 76 patients scanned using retrospective ECG gating. Forty-seven patients were scanned by the predicted triggering windows. The optimal positions of exposure intervals according to different heart rates were evaluated. Optimal image quality, radiation dose, and diagnostic accuracy were then investigated by applying optimal triggering windows. The optimal ECG pulsing windows were determined as follows: when heart rate was <70 beats per minute, the exposure windows should be preset at 60%–80%; for a heart rate 70–90 beats per minute at 70%–90%; and for a heart rate ≥90 beats per minute at 30%–50%. The radiation dose for patients scanned with prospective ECG gating was significantly lower (5.9 versus 12.9 mSv, P < 0.001). However, because two or three heart beats were needed when heart rate was >70 beats per minute, the radiation dose increased with increasing heart rate for both retrospective and prospective ECG gating (r = 0.64, P < 0.001 and r = 0.59, P < 0.001, respectively). On the basis of a per segment analysis, overall sensitivity was 98.0% (49/50), specificity was 99.2% (602/607), the positive predictive value was 90.7% (49/54), and the negative predictive value was 99.8% (602/603). In conclusion, DVCT has the potential to provide high image quality across a wide range of heart rates using an optimized ECG pulsing window. However, it is recommended to control heart rate below 70 beats per min

This paper deals with the issues of observer-based reliable stabilization and H∞ control for a class of continuous-time switched Lipschitz nonlinear systems in the sense that actuators suffer a "destabilizing failure". When the never-faulty actuators ca