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Your search keyword '"Mignogna, Michele Davide"' showing total 2 results
Start Over Author "Mignogna, Michele Davide" Publication Type Electronic Resources
2 results on '"Mignogna, Michele Davide"'

1. Anxiety and depression in keratotic oral lichen planus: a multicentric study from the SIPMO

Author

Adamo, Daniela, Calabria, Elena, Canfora, Federica, Coppola, Noemi, Leuci, Stefania, Mignogna, Martina, Muzio, Lorenzo Lo, Spirito, Francesca, Giuliani, Michele, Azzi, Lorenzo, Dani, Marta, Colella, Giuseppe, Colella, Chiara, Montebugnoli, Lucio, Gissi, Davide Bartolomeo, Gabriele, Mario, Nisi, Marco, Sardella, Andrea, Lodi, Giovanni, Varoni, Elena Maria, Giudice, Amerigo, Antonelli, Alessandro, Gambino, Alessio, Antonucci, Giuliana, Vescovi, Paolo, Meleti, Marco, Majorana, Alessandra, Bardellini, Elena, Campisi, Giuseppina, Panzarella, Vera, Spadari, Francesco, Garagiola, Umberto, Pentenero, Monica, Sutera, Samuele, Biasotto, Matteo, Ottaviani, Giulia, Gobbo, Margherita, Nardini, Luca Guarda, Romeo, Umberto, Tenore, Gianluca, Serpico, Rosario, Lucchese, Alberta, Lajolo, Carlo, Gioco, Gioele, Aria, Massimo, D'Aniello, Luca, Mignogna, Michele Davide, Lajolo, Carlo (ORCID:0000-0003-4663-9734), Gioco, Gioele (ORCID:0000-0002-8637-2029), Adamo, Daniela, Calabria, Elena, Canfora, Federica, Coppola, Noemi, Leuci, Stefania, Mignogna, Martina, Muzio, Lorenzo Lo, Spirito, Francesca, Giuliani, Michele, Azzi, Lorenzo, Dani, Marta, Colella, Giuseppe, Colella, Chiara, Montebugnoli, Lucio, Gissi, Davide Bartolomeo, Gabriele, Mario, Nisi, Marco, Sardella, Andrea, Lodi, Giovanni, Varoni, Elena Maria, Giudice, Amerigo, Antonelli, Alessandro, Gambino, Alessio, Antonucci, Giuliana, Vescovi, Paolo, Meleti, Marco, Majorana, Alessandra, Bardellini, Elena, Campisi, Giuseppina, Panzarella, Vera, Spadari, Francesco, Garagiola, Umberto, Pentenero, Monica, Sutera, Samuele, Biasotto, Matteo, Ottaviani, Giulia, Gobbo, Margherita, Nardini, Luca Guarda, Romeo, Umberto, Tenore, Gianluca, Serpico, Rosario, Lucchese, Alberta, Lajolo, Carlo, Gioco, Gioele, Aria, Massimo, D'Aniello, Luca, Mignogna, Michele Davide, Lajolo, Carlo (ORCID:0000-0003-4663-9734), and Gioco, Gioele (ORCID:0000-0002-8637-2029)

Abstract

ObjectivesOral lichen planus with exclusive keratotic reticular, papular, and/or plaque-like lesions (K-OLP) is a clinical pattern of OLP that may be associated with a complex symptomatology and psychological alteration. The aim of the study was to evaluate the prevalence of anxiety (A) and depression (D) in patients with K-OLP, analyzing the potential predictors which can affect mental health status.MethodsThree hundred K-OLP patients versus 300 healthy controls (HC) were recruited in 15 Italian universities. The Numeric Rating Scale (NRS), Total Pain Rating Index (T-PRI), and Hamilton Rating Scales for Depression and for Anxiety (HAM-D and HAM-A) were administered.ResultsThe K-OLP patients showed statistically higher scores in the NRS, T-PRI, HAM-D, and HAM-A compared with the HC (p-value < 0.001*). A and D were found in 158 (52.7%) and 148 (49.3%) K-OLP patients. Strong linear correlations were identified between HAM-A, HAM-D, NRS, T-PRI, and employment status and between HAM-D, HAM-A, NRS, T-PRI, employment status, and female gender. Multivariate logistic regression revealed that HAM-D and HAM-A showed the greatest increase in the R2 value for A and D in the K-OLP patients, respectively (DR2 = 55.5% p-value < 0.001**; DR2 = 56.5% p-value < 0.001**).ConclusionsThe prevalence of A and D is higher in the K-OLP patients compared with the HC, also found in K-OLP subjects without pain, suggesting that the processing of pain may be in a certain way independent of the processing of mood.

Published
2023

2. Where do you live? North versus Central-South differences in relation to Italian patients with oral lichen planus: a cross-sectional study from the SIPMO (Italian Society of Oral Pathology and Medicine)

Author

Adamo, Daniela, Calabria, Elena, Canfora, Federica, Coppola, Noemi, Lo Muzio, Lorenzo, Spirito, Francesca, Giuliani, Michele, Azzi, Lorenzo, Maurino, Vittorio, Colella, Giuseppe, Colella, Chiara, Montebugnoli, Lucio, Gissi, Davide Bartolomeo, Gabriele, Mario, Nisi, Marco, Sardella, Andrea, Lodi, Giovanni, Varoni, Elena Maria, Giudice, Amerigo, Antonelli, Alessandro, Arduino, Paolo Giacomo, Gambino, Alessio, Vescovi, Paolo, Majorana, Alessandra, Bardellini, Elena, Campisi, Giuseppina, Panzarella, Vera, Spadari, Francesco, Garagiola, Umberto, Pentenero, Monica, Sutera, Samuele, Biasotto, Matteo, Ottaviani, Giulia, Gobbo, Margherita, Guarda Nardini, Luca, Romeo, Umberto, Tenore, Gianluca, Serpico, Rosario, Lucchese, Alberta, Lajolo, Carlo, Rupe, Cosimo, Aria, Massimo, D'Aniello, Luca, Mignogna, Michele Davide, Lajolo, Carlo (ORCID:0000-0003-4663-9734), Adamo, Daniela, Calabria, Elena, Canfora, Federica, Coppola, Noemi, Lo Muzio, Lorenzo, Spirito, Francesca, Giuliani, Michele, Azzi, Lorenzo, Maurino, Vittorio, Colella, Giuseppe, Colella, Chiara, Montebugnoli, Lucio, Gissi, Davide Bartolomeo, Gabriele, Mario, Nisi, Marco, Sardella, Andrea, Lodi, Giovanni, Varoni, Elena Maria, Giudice, Amerigo, Antonelli, Alessandro, Arduino, Paolo Giacomo, Gambino, Alessio, Vescovi, Paolo, Majorana, Alessandra, Bardellini, Elena, Campisi, Giuseppina, Panzarella, Vera, Spadari, Francesco, Garagiola, Umberto, Pentenero, Monica, Sutera, Samuele, Biasotto, Matteo, Ottaviani, Giulia, Gobbo, Margherita, Guarda Nardini, Luca, Romeo, Umberto, Tenore, Gianluca, Serpico, Rosario, Lucchese, Alberta, Lajolo, Carlo, Rupe, Cosimo, Aria, Massimo, D'Aniello, Luca, Mignogna, Michele Davide, and Lajolo, Carlo (ORCID:0000-0003-4663-9734)

Abstract

Background Oral lichen planus (OLP) is an immune-mediated inflammatory chronic disease of the oral mucosa, with different patterns of clinical manifestations which range from keratotic manifestations (K-OLP) to predominantly non-keratotic lesions (nK-OLP). The aim of the study was to analyze the differences in the clinical, psychological profile and symptoms between Italian patients of the North and Central-South with K-OLP and nK-OLP. Methods 270 K-OLP and 270 nK-OLP patients were recruited in 15 Italian universities. The Numeric Rating Scale (NRS), Total Pain Rating Index (T-PRI), Hamilton Rating Scales for Depression and for Anxiety (HAM-D and HAM-A), Pittsburgh Sleep Quality Index (PSQI), and Epworth Sleepiness Scale (ESS) were administered. Results The Central-South K-OLP (CS-K-OLP) patients reported a higher frequency of pain/burning compared with the K-OLP patients of the North (N-K-OLP) with higher scores in the NRS and T-PRI (p value < 0.001**). The CS-K-OLP and the CS-nK-OLP patients showed higher scores in the HAM-D, HAM-A, PSQI and ESS compared with the Northern patients (p value < 0.001**). Multivariate logistic regression revealed that the NRS and T-PRI showed the greatest increase in the R2 value for the CS-K-OLP (DR2 = 9.6%; p value < 0.001**; DR2 = 9.7% p value < 0.001**; respectively) and that the oral symptoms (globus, itching and intraoral foreign body sensation) and PSQI showed the greatest increase in the R2 value for the CS-nK-OLP (DR2 = 5.6%; p value < 0.001**; DR2 = 4.5% p value < 0.001** respectively). Conclusions Pain and mood disorders are predominant in patients with OLP in the Central-South of Italy. Clinicians should consider that the geographical living area may explain the differences in oral symptoms and psychological profile in OLP.

Published
2022

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