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2 results on '"Munnur D"'

1. NR4A Nuclear Receptors Target Poly-ADP-Ribosylated DNA-PKcs Protein to Promote DNA Repair

Author

Munnur, D, Somers, J, Skalka, G, Weston, R, Jukes-Jones, R, Bhogadia, M, Dominguez, C, Cain, K, Ahel, I, Malewicz, M, Munnur, D, Somers, J, Skalka, G, Weston, R, Jukes-Jones, R, Bhogadia, M, Dominguez, C, Cain, K, Ahel, I, and Malewicz, M

Abstract

© 2019 The Author(s) DNA damage induces poly-ADP-ribosylation (PARylation) of repair factors recruited to DNA lesions. Munnur et al. identify a zinc-finger-type poly-ADP-ribose-binding domain in NR4A nuclear orphan receptors that targets PARylated DNA-PKcs repair kinase, facilitating its autophosphorylation and repair of double-strand DNA breaks.

Published
2019

2. NR4A Nuclear Receptors Target Poly-ADP-Ribosylated DNA-PKcs Protein to Promote DNA Repair

Author

Munnur, D, Somers, J, Skalka, G, Weston, R, Jukes-Jones, R, Bhogadia, M, Dominguez, C, Cain, K, Ahel, I, Malewicz, M, Munnur, D, Somers, J, Skalka, G, Weston, R, Jukes-Jones, R, Bhogadia, M, Dominguez, C, Cain, K, Ahel, I, and Malewicz, M

Abstract

© 2019 The Author(s) DNA damage induces poly-ADP-ribosylation (PARylation) of repair factors recruited to DNA lesions. Munnur et al. identify a zinc-finger-type poly-ADP-ribose-binding domain in NR4A nuclear orphan receptors that targets PARylated DNA-PKcs repair kinase, facilitating its autophosphorylation and repair of double-strand DNA breaks.

Published
2019

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