Author: "Pedersen T" / Publication Type: Electronic Resources - Searchworks@Jio Institute Digital Library Search Results

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1. Experimental confirmation of efficient island divertor operation and successful neoclassical transport optimization in Wendelstein 7-X

Author: Pedersen, T, Abramovic, I, Agostinetti, P, Torres, M, Akaslompolo, S, Belloso, J, Aleynikov, P, Aleynikova, K, Alhashimi, M, Ali, A, Allen, N, Alonso, A, Anda, G, Andreeva, T, Angioni, C, Arkhipov, A, Arnold, A, Asad, W, Ascasibar, E, Aumeunier, M, Avramidis, K, Aymerich, E, Baek, S, Bahner, J, Baillod, A, Balden, M, Baldzuhn, J, Ballinger, S, Banduch, M, Bannmann, S, Navarro, A, Barbui, T, Beidler, C, Belafdil, C, Bencze, A, Benndorf, A, Beurskens, M, Biedermann, C, Biletskyi, O, Blackwell, B, Blatzheim, M, Bluhm, T, Bockenhoff, D, Bongiovi, G, Borchardt, M, Borodin, D, Boscary, J, Bosch, H, Bosmann, T, Boswirth, B, Bottger, L, Bottino, A, Bozhenkov, S, Brakel, R, Brandt, C, Brauer, T, Braune, H, Brezinsek, S, Brunner, K, Buller, S, Burhenn, R, Bussiahn, R, Buttenschon, B, Buzas, A, Bykov, V, Calvo, I, Mata, K, Caminal, I, Cannas, B, Cappa, A, Carls, A, Carovani, F, Carr, M, Carralero, D, Carvalho, B, Casas, J, Castano-Bardawil, D, Castejon, F, Chaudhary, N, Chelis, I, Chomiczewska, A, Coenen, J, Cole, M, Cordella, F, Corre, Y, Crombe, K, Cseh, G, Csillag, B, Damm, H, Day, C, de Baar, M, De la Cal, E, Degenkolbe, S, Demby, A, Denk, S, Dhard, C, Di Siena, A, Dinklage, A, Dittmar, T, Dreval, M, Drevlak, M, Drewelow, P, Drews, P, Dunai, D, Edlund, E, Effenberg, F, Ehrke, G, Endler, M, Ennis, D, Escoto, F, Estrada, T, Fable, E, Fahrenkamp, N, Fanni, A, Faustin, J, Fellinger, J, Feng, Y, Figacz, W, Flom, E, Ford, O, Fornal, T, Frerichs, H, Freundt, S, Fuchert, G, Fukuyama, M, Fullenbach, F, Gantenbein, G, Gao, Y, Garcia, K, Regana, J, Garcia-Cortes, I, Gaspar, J, Gates, D, Geiger, J, Geiger, B, Giudicotti, L, Gonzalez, A, Goriaev, A, Gradic, D, Grahl, M, Graves, J, Green, J, Grelier, E, Greuner, H, Gross, S, Grote, H, Groth, M, Gruca, M, Grulke, O, Grun, M, Arnaiz, J, Gunter, S, Haak, V, Haas, M, Hacker, P, Hakola, A, Hallenbert, A, Hammond, K, Han, X, Hansen, S, Harris, J, Hartfuss, H, Hartmann, D, Hathiramani, D, Hatzky, R, Hawke, J, Hegedus, S, Hein, B, Heinemann, B, Helander, P, Henneberg, S, Hergenhahn, U, Hidalgo, C, Hindenlang, F, Hirsch, M, Hofel, U, Hollfeld, K, Holtz, A, Hopf, D, Hoschen, D, Houry, M, Howard, J, Huang, X, Hubeny, M, Hudson, S, Ida, K, Igitkhanov, Y, Igochine, V, Illy, S, Ionita-Schrittwieser, C, Isobe, M, Jablczynska, M, Jablonski, S, Jagielski, B, Jakubowski, M, van Vuuren, A, Jelonnek, J, Jenko, F, Jensen, T, Jenzsch, H, Junghanns, P, Kaczmarczyk, J, Kallmeyer, J, Kamionka, U, Kandler, M, Kasilov, S, Kazakov, Y, Kennedy, D, Kharwandikar, A, Khokhlov, M, Kiefer, C, Killer, C, Kirschner, A, Kleiber, R, Klinger, T, Klose, S, Knauer, J, Knieps, A, Kochl, F, Kocsis, G, Kolesnichenko, Y, Konies, A, Konig, R, Kontula, J, Kornejew, P, Koschinsky, J, Kozulia, M, Kramer-Flecken, A, Krampitz, R, Krause, M, Krawczyk, N, Kremeyer, T, Krier, L, Kriete, D, Krychowiak, M, Ksiazek, I, Kubkowska, M, Kuczynski, M, Kuhner, G, Kumar, A, Kurki-Suonio, T, Kwak, S, Landreman, M, Lang, P, Langenberg, A, Laqua, H, Laube, R, Lazerson, S, Lewerentz, M, Li, C, Liang, Y, Linsmeier, C, Lion, J, Litnovsky, A, Liu, S, Lobsien, J, Loizu, J, Lore, J, Lorenz, A, Losada, U, Louche, F, Lunsford, R, Lutsenko, V, Machielsen, M, Mackel, F, Maisano-Brown, J, Maj, O, Makowski, D, Manduchi, G, Maragkoudakis, E, Marchuk, O, Marsen, S, Martines, E, Martinez-Fernandez, J, Marushchenko, M, Masuzaki, S, Maurer, D, Mayer, M, Mccarthy, K, Mccormack, O, Mcneely, P, Meister, H, Mendelevitch, B, Mendes, S, Merlo, A, Messian, A, Mielczarek, A, Mishchenko, O, Missal, B, Mitteau, R, Moiseenko, V, Mollen, A, Moncada, V, Monnich, T, Morisaki, T, Moseev, D, Motojima, G, Mulas, S, Mulsow, M, Nagel, M, Naujoks, D, Naulin, V, Neelis, T, Neilson, H, Neu, R, Neubauer, O, Neuner, U, Nicolai, D, Nielsen, S, Niemann, H, Nishiza, T, Nishizawa, T, Nuhrenberg, C, Ochoukov, R, Oelmann, J, Offermanns, G, Ogawa, K, Okamura, S, Olmanns, J, Ongena, J, Oosterbeek, J, Otte, M, Pablant, N, Alvarez, N, Pandey, A, Pasch, E, Pavlichenko, R, Pavone, A, Pawelec, E, Pechstein, G, Pelka, G, Perseo, V, Peterson, B, Pilopp, D, Pingel, S, Pisano, F, Plockl, B, Plunk, G, Poloskei, P, Pompe, B, Popov, A, Porkolab, M, Proll, J, Pueschel, M, Puiatti, M, Sitjes, A, Purps, F, Rahbarnia, K, Rasinski, M, Rasmussen, J, Reiman, A, Reimold, F, Reisner, M, Reiter, D, Richou, M, Riedl, R, Riemann, J, Risse, K, Roberg-Clark, G, Rohde, V, Romazanov, J, Rondeshagen, D, Rong, P, Rudischhauser, L, Rummel, T, Rummel, K, Runov, A, Rust, N, Ryc, L, Salembier, P, Salewski, M, Sanchez, E, Satake, S, Satheeswaran, G, Schacht, J, Scharff, E, Schauer, F, Schilling, J, Schlisio, G, Schmid, K, Schmitt, J, Schmitz, O, Schneider, W, Schneider, M, Schneider, P, Schrittwieser, R, Schroder, T, Schroder, M, Schroeder, R, Schweer, B, Schworer, D, Scott, E, Shanahan, B, Sias, G, Sichta, P, Singer, M, Sinha, P, Siplia, S, Slaby, C, Sleczka, M, Smith, H, Smoniewski, J, Sonnendrucker, E, Spolaore, M, Spring, A, Stadler, R, Stanczak, D, Stange, T, Stepanov, I, Stephey, L, Stober, J, Stroth, U, Strumberger, E, Suzuki, C, Suzuki, Y, Svensson, J, Szabolics, T, Szepesi, T, Szucs, M, Tabares, F, Tamura, N, Tancetti, A, Tantos, C, Terry, J, Thienpondt, H, Thomsen, H, Thumm, M, Travere, J, Traverso, P, Tretter, J, Trier, E, Mora, H, Tsujimura, T, Turkin, Y, Tykhyi, A, Unterberg, B, van Eeten, P, van Milligen, B, van Schoor, M, Vano, L, Varoutis, S, Vecsei, M, Vela, L, Velasco, J, Vervier, M, Vianello, N, Viebke, H, Vilbrandt, R, Vogel, G, Vogt, N, Volkhausen, C, von Stechow, A, Wagner, F, Wang, E, Wang, H, Warmer, F, Wauters, T, Wegener, L, Wegner, T, Weir, G, Wenzel, U, White, A, Wilde, F, Wilms, F, Windisch, T, Winkler, M, Winter, A, Winters, V, Wolf, R, Wright, A, Wurden, G, Xanthopoulos, P, Xu, S, Yamada, H, Yamaguchi, H, Yokoyama, M, Yoshinuma, M, Yu, Q, Zamanov, M, Zanini, M, Zarnstorff, M, Zhang, D, Zhou, S, Zhu, J, Zhu, C, Zilker, M, Zocco, A, Zohm, H, Zoletnik, S, Zsuga, L, Pedersen T. S., Abramovic I., Agostinetti P., Torres M. A., Akaslompolo S., Belloso J. A., Aleynikov P., Aleynikova K., Alhashimi M., Ali A., Allen N., Alonso A., Anda G., Andreeva T., Angioni C., Arkhipov A., Arnold A., Asad W., Ascasibar E., Aumeunier M. -H., Avramidis K., Aymerich E., Baek S. -G., Bahner J., Baillod A., Balden M., Baldzuhn J., Ballinger S., Banduch M., Bannmann S., Navarro A. B., Barbui T., Beidler C., Belafdil C., Bencze A., Benndorf A., Beurskens M., Biedermann C., Biletskyi O., Blackwell B., Blatzheim M., Bluhm T., Bockenhoff D., Bongiovi G., Borchardt M., Borodin D., Boscary J., Bosch H., Bosmann T., Boswirth B., Bottger L., Bottino A., Bozhenkov S., Brakel R., Brandt C., Brauer T., Braune H., Brezinsek S., Brunner K., Buller S., Burhenn R., Bussiahn R., Buttenschon B., Buzas A., Bykov V., Calvo I., Mata K. C., Caminal I., Cannas B., Cappa A., Carls A., Carovani F., Carr M., Carralero D., Carvalho B., Casas J., Castano-Bardawil D., Castejon F., Chaudhary N., Chelis I., Chomiczewska A., Coenen J. W., Cole M., Cordella F., Corre Y., Crombe K., Cseh G., Csillag B., Damm H., Day C., de Baar M., De la Cal E., Degenkolbe S., Demby A., Denk S., Dhard C., Di Siena A., Dinklage A., Dittmar T., Dreval M., Drevlak M., Drewelow P., Drews P., Dunai D., Edlund E., Effenberg F., Ehrke G., Endler M., Ennis D. A., Escoto F. J., Estrada T., Fable E., Fahrenkamp N., Fanni A., Faustin J., Fellinger J., Feng Y., Figacz W., Flom E., Ford O., Fornal T., Frerichs H., Freundt S., Fuchert G., Fukuyama M., Fullenbach F., Gantenbein G., Gao Y., Garcia K., Regana J. M. G., Garcia-Cortes I., Gaspar J., Gates D. A., Geiger J., Geiger B., Giudicotti L., Gonzalez A., Goriaev A., Gradic D., Grahl M., Graves J. P., Green J., Grelier E., Greuner H., Gross S., Grote H., Groth M., Gruca M., Grulke O., Grun M., Arnaiz J. G., Gunter S., Haak V., Haas M., Hacker P., Hakola A., Hallenbert A., Hammond K., Han X., Hansen S. K., Harris J. H., Hartfuss H., Hartmann D., Hathiramani D., Hatzky R., Hawke J., Hegedus S., Hein B., Heinemann B., Helander P., Henneberg S., Hergenhahn U., Hidalgo C., Hindenlang F., Hirsch M., Hofel U., Hollfeld K. P., Holtz A., Hopf D., Hoschen D., Houry M., Howard J., Huang X., Hubeny M., Hudson S., Ida K., Igitkhanov Y., Igochine V., Illy S., Ionita-Schrittwieser C., Isobe M., Jablczynska M., Jablonski S., Jagielski B., Jakubowski M., van Vuuren A. J., Jelonnek J., Jenko F., Jensen T., Jenzsch H., Junghanns P., Kaczmarczyk J., Kallmeyer J., Kamionka U., Kandler M., Kasilov S., Kazakov Y., Kennedy D., Kharwandikar A., Khokhlov M., Kiefer C., Killer C., Kirschner A., Kleiber R., Klinger T., Klose S., Knauer J., Knieps A., Kochl F., Kocsis G., Kolesnichenko Ya. I., Konies A., Konig R., Kontula J., Kornejew P., Koschinsky J., Kozulia M. M., Kramer-Flecken A., Krampitz R., Krause M., Krawczyk N., Kremeyer T., Krier L., Kriete D. M., Krychowiak M., Ksiazek I., Kubkowska M., Kuczynski M., Kuhner G., Kumar A., Kurki-Suonio T., Kwak S., Landreman M., Lang P. T., Langenberg A., Laqua H. P., Laqua H., Laube R., Lazerson S., Lewerentz M., Li C., Liang Y., Linsmeier Ch., Lion J., Litnovsky A., Liu S., Lobsien J., Loizu J., Lore J., Lorenz A., Losada U., Louche F., Lunsford R., Lutsenko V., Machielsen M., Mackel F., Maisano-Brown J., Maj O., Makowski D., Manduchi G., Maragkoudakis E., Marchuk O., Marsen S., Martines E., Martinez-Fernandez J., Marushchenko M., Masuzaki S., Maurer D., Mayer M., McCarthy K. J., McCormack O., McNeely P., Meister H., Mendelevitch B., Mendes S., Merlo A., Messian A., Mielczarek A., Mishchenko O., Missal B., Mitteau R., Moiseenko V. E., Mollen A., Moncada V., Monnich T., Morisaki T., Moseev D., Motojima G., Mulas S., Mulsow M., Nagel M., Naujoks D., Naulin V., Neelis T., Neilson H., Neu R., Neubauer O., Neuner U., Nicolai D., Nielsen S. K., Niemann H., Nishiza T., Nishizawa T., Nuhrenberg C., Ochoukov R., Oelmann J., Offermanns G., Ogawa K., Okamura S., Olmanns J., Ongena J., Oosterbeek J., Otte M., Pablant N., Alvarez N. P., Pandey A., Pasch E., Pavlichenko R., Pavone A., Pawelec E., Pechstein G., Pelka G., Perseo V., Peterson B., Pilopp D., Pingel S., Pisano F., Plockl B., Plunk G., Poloskei P., Pompe B., Popov A., Porkolab M., Proll J., Pueschel M. J., Puiatti M. -E., Sitjes A. P., Purps F., Rahbarnia K., Rasinski M., Rasmussen J., Reiman A., Reimold F., Reisner M., Reiter D., Richou M., Riedl R., Riemann J., Risse K., Roberg-Clark G., Rohde V., Romazanov J., Rondeshagen D., Rong P., Rudischhauser L., Rummel T., Rummel K., Runov A., Rust N., Ryc L., Salembier P., Salewski M., Sanchez E., Satake S., Satheeswaran G., Schacht J., Scharff E., Schauer F., Schilling J., Schlisio G., Schmid K., Schmitt J., Schmitz O., Schneider W., Schneider M., Schneider P., Schrittwieser R., Schroder T., Schroder M., Schroeder R., Schweer B., Schworer D., Scott E., Shanahan B., Sias G., Sichta P., Singer M., Sinha P., Siplia S., Slaby C., Sleczka M., Smith H., Smoniewski J., Sonnendrucker E., Spolaore M., Spring A., Stadler R., Stanczak D., Stange T., Stepanov I., Stephey L., Stober J., Stroth U., Strumberger E., Suzuki C., Suzuki Y., Svensson J., Szabolics T., Szepesi T., Szucs M., Tabares F. L., Tamura N., Tancetti A., Tantos C., Terry J., Thienpondt H., Thomsen H., Thumm M., Travere J. M., Traverso P., Tretter J., Trier E., Mora H. T., Tsujimura T., Turkin Y., Tykhyi A., Unterberg B., van Eeten P., van Milligen B. Ph., van Schoor M., Vano L., Varoutis S., Vecsei M., Vela L., Velasco J. L., Vervier M., Vianello N., Viebke H., Vilbrandt R., Vogel G., Vogt N., Volkhausen C., von Stechow A., Wagner F., Wang E., Wang H., Warmer F., Wauters T., Wegener L., Wegner T., Weir G., Wenzel U., White A., Wilde F., Wilms F., Windisch T., Winkler M., Winter A., Winters V., Wolf R., Wright A. M., Wurden G. A., Xanthopoulos P., Xu S., Yamada H., Yamaguchi H., Yokoyama M., Yoshinuma M., Yu Q., Zamanov M., Zanini M., Zarnstorff M., Zhang D., Zhou S., Zhu J., Zhu C., Zilker M., Zocco A., Zohm H., Zoletnik S., Zsuga L., Pedersen, T, Abramovic, I, Agostinetti, P, Torres, M, Akaslompolo, S, Belloso, J, Aleynikov, P, Aleynikova, K, Alhashimi, M, Ali, A, Allen, N, Alonso, A, Anda, G, Andreeva, T, Angioni, C, Arkhipov, A, Arnold, A, Asad, W, Ascasibar, E, Aumeunier, M, Avramidis, K, Aymerich, E, Baek, S, Bahner, J, Baillod, A, Balden, M, Baldzuhn, J, Ballinger, S, Banduch, M, Bannmann, S, Navarro, A, Barbui, T, Beidler, C, Belafdil, C, Bencze, A, Benndorf, A, Beurskens, M, Biedermann, C, Biletskyi, O, Blackwell, B, Blatzheim, M, Bluhm, T, Bockenhoff, D, Bongiovi, G, Borchardt, M, Borodin, D, Boscary, J, Bosch, H, Bosmann, T, Boswirth, B, Bottger, L, Bottino, A, Bozhenkov, S, Brakel, R, Brandt, C, Brauer, T, Braune, H, Brezinsek, S, Brunner, K, Buller, S, Burhenn, R, Bussiahn, R, Buttenschon, B, Buzas, A, Bykov, V, Calvo, I, Mata, K, Caminal, I, Cannas, B, Cappa, A, Carls, A, Carovani, F, Carr, M, Carralero, D, Carvalho, B, Casas, J, Castano-Bardawil, D, Castejon, F, Chaudhary, N, Chelis, I, Chomiczewska, A, Coenen, J, Cole, M, Cordella, F, Corre, Y, Crombe, K, Cseh, G, Csillag, B, Damm, H, Day, C, de Baar, M, De la Cal, E, Degenkolbe, S, Demby, A, Denk, S, Dhard, C, Di Siena, A, Dinklage, A, Dittmar, T, Dreval, M, Drevlak, M, Drewelow, P, Drews, P, Dunai, D, Edlund, E, Effenberg, F, Ehrke, G, Endler, M, Ennis, D, Escoto, F, Estrada, T, Fable, E, Fahrenkamp, N, Fanni, A, Faustin, J, Fellinger, J, Feng, Y, Figacz, W, Flom, E, Ford, O, Fornal, T, Frerichs, H, Freundt, S, Fuchert, G, Fukuyama, M, Fullenbach, F, Gantenbein, G, Gao, Y, Garcia, K, Regana, J, Garcia-Cortes, I, Gaspar, J, Gates, D, Geiger, J, Geiger, B, Giudicotti, L, Gonzalez, A, Goriaev, A, Gradic, D, Grahl, M, Graves, J, Green, J, Grelier, E, Greuner, H, Gross, S, Grote, H, Groth, M, Gruca, M, Grulke, O, Grun, M, Arnaiz, J, Gunter, S, Haak, V, Haas, M, Hacker, P, Hakola, A, Hallenbert, A, Hammond, K, Han, X, Hansen, S, Harris, J, Hartfuss, H, Hartmann, D, Hathiramani, D, Hatzky, R, Hawke, J, Hegedus, S, Hein, B, Heinemann, B, Helander, P, Henneberg, S, Hergenhahn, U, Hidalgo, C, Hindenlang, F, Hirsch, M, Hofel, U, Hollfeld, K, Holtz, A, Hopf, D, Hoschen, D, Houry, M, Howard, J, Huang, X, Hubeny, M, Hudson, S, Ida, K, Igitkhanov, Y, Igochine, V, Illy, S, Ionita-Schrittwieser, C, Isobe, M, Jablczynska, M, Jablonski, S, Jagielski, B, Jakubowski, M, van Vuuren, A, Jelonnek, J, Jenko, F, Jensen, T, Jenzsch, H, Junghanns, P, Kaczmarczyk, J, Kallmeyer, J, Kamionka, U, Kandler, M, Kasilov, S, Kazakov, Y, Kennedy, D, Kharwandikar, A, Khokhlov, M, Kiefer, C, Killer, C, Kirschner, A, Kleiber, R, Klinger, T, Klose, S, Knauer, J, Knieps, A, Kochl, F, Kocsis, G, Kolesnichenko, Y, Konies, A, Konig, R, Kontula, J, Kornejew, P, Koschinsky, J, Kozulia, M, Kramer-Flecken, A, Krampitz, R, Krause, M, Krawczyk, N, Kremeyer, T, Krier, L, Kriete, D, Krychowiak, M, Ksiazek, I, Kubkowska, M, Kuczynski, M, Kuhner, G, Kumar, A, Kurki-Suonio, T, Kwak, S, Landreman, M, Lang, P, Langenberg, A, Laqua, H, Laube, R, Lazerson, S, Lewerentz, M, Li, C, Liang, Y, Linsmeier, C, Lion, J, Litnovsky, A, Liu, S, Lobsien, J, Loizu, J, Lore, J, Lorenz, A, Losada, U, Louche, F, Lunsford, R, Lutsenko, V, Machielsen, M, Mackel, F, Maisano-Brown, J, Maj, O, Makowski, D, Manduchi, G, Maragkoudakis, E, Marchuk, O, Marsen, S, Martines, E, Martinez-Fernandez, J, Marushchenko, M, Masuzaki, S, Maurer, D, Mayer, M, Mccarthy, K, Mccormack, O, Mcneely, P, Meister, H, Mendelevitch, B, Mendes, S, Merlo, A, Messian, A, Mielczarek, A, Mishchenko, O, Missal, B, Mitteau, R, Moiseenko, V, Mollen, A, Moncada, V, Monnich, T, Morisaki, T, Moseev, D, Motojima, G, Mulas, S, Mulsow, M, Nagel, M, Naujoks, D, Naulin, V, Neelis, T, Neilson, H, Neu, R, Neubauer, O, Neuner, U, Nicolai, D, Nielsen, S, Niemann, H, Nishiza, T, Nishizawa, T, Nuhrenberg, C, Ochoukov, R, Oelmann, J, Offermanns, G, Ogawa, K, Okamura, S, Olmanns, J, Ongena, J, Oosterbeek, J, Otte, M, Pablant, N, Alvarez, N, Pandey, A, Pasch, E, Pavlichenko, R, Pavone, A, Pawelec, E, Pechstein, G, Pelka, G, Perseo, V, Peterson, B, Pilopp, D, Pingel, S, Pisano, F, Plockl, B, Plunk, G, Poloskei, P, Pompe, B, Popov, A, Porkolab, M, Proll, J, Pueschel, M, Puiatti, M, Sitjes, A, Purps, F, Rahbarnia, K, Rasinski, M, Rasmussen, J, Reiman, A, Reimold, F, Reisner, M, Reiter, D, Richou, M, Riedl, R, Riemann, J, Risse, K, Roberg-Clark, G, Rohde, V, Romazanov, J, Rondeshagen, D, Rong, P, Rudischhauser, L, Rummel, T, Rummel, K, Runov, A, Rust, N, Ryc, L, Salembier, P, Salewski, M, Sanchez, E, Satake, S, Satheeswaran, G, Schacht, J, Scharff, E, Schauer, F, Schilling, J, Schlisio, G, Schmid, K, Schmitt, J, Schmitz, O, Schneider, W, Schneider, M, Schneider, P, Schrittwieser, R, Schroder, T, Schroder, M, Schroeder, R, Schweer, B, Schworer, D, Scott, E, Shanahan, B, Sias, G, Sichta, P, Singer, M, Sinha, P, Siplia, S, Slaby, C, Sleczka, M, Smith, H, Smoniewski, J, Sonnendrucker, E, Spolaore, M, Spring, A, Stadler, R, Stanczak, D, Stange, T, Stepanov, I, Stephey, L, Stober, J, Stroth, U, Strumberger, E, Suzuki, C, Suzuki, Y, Svensson, J, Szabolics, T, Szepesi, T, Szucs, M, Tabares, F, Tamura, N, Tancetti, A, Tantos, C, Terry, J, Thienpondt, H, Thomsen, H, Thumm, M, Travere, J, Traverso, P, Tretter, J, Trier, E, Mora, H, Tsujimura, T, Turkin, Y, Tykhyi, A, Unterberg, B, van Eeten, P, van Milligen, B, van Schoor, M, Vano, L, Varoutis, S, Vecsei, M, Vela, L, Velasco, J, Vervier, M, Vianello, N, Viebke, H, Vilbrandt, R, Vogel, G, Vogt, N, Volkhausen, C, von Stechow, A, Wagner, F, Wang, E, Wang, H, Warmer, F, Wauters, T, Wegener, L, Wegner, T, Weir, G, Wenzel, U, White, A, Wilde, F, Wilms, F, Windisch, T, Winkler, M, Winter, A, Winters, V, Wolf, R, Wright, A, Wurden, G, Xanthopoulos, P, Xu, S, Yamada, H, Yamaguchi, H, Yokoyama, M, Yoshinuma, M, Yu, Q, Zamanov, M, Zanini, M, Zarnstorff, M, Zhang, D, Zhou, S, Zhu, J, Zhu, C, Zilker, M, Zocco, A, Zohm, H, Zoletnik, S, Zsuga, L, Pedersen T. S., Abramovic I., Agostinetti P., Torres M. A., Akaslompolo S., Belloso J. A., Aleynikov P., Aleynikova K., Alhashimi M., Ali A., Allen N., Alonso A., Anda G., Andreeva T., Angioni C., Arkhipov A., Arnold A., Asad W., Ascasibar E., Aumeunier M. -H., Avramidis K., Aymerich E., Baek S. -G., Bahner J., Baillod A., Balden M., Baldzuhn J., Ballinger S., Banduch M., Bannmann S., Navarro A. B., Barbui T., Beidler C., Belafdil C., Bencze A., Benndorf A., Beurskens M., Biedermann C., Biletskyi O., Blackwell B., Blatzheim M., Bluhm T., Bockenhoff D., Bongiovi G., Borchardt M., Borodin D., Boscary J., Bosch H., Bosmann T., Boswirth B., Bottger L., Bottino A., Bozhenkov S., Brakel R., Brandt C., Brauer T., Braune H., Brezinsek S., Brunner K., Buller S., Burhenn R., Bussiahn R., Buttenschon B., Buzas A., Bykov V., Calvo I., Mata K. C., Caminal I., Cannas B., Cappa A., Carls A., Carovani F., Carr M., Carralero D., Carvalho B., Casas J., Castano-Bardawil D., Castejon F., Chaudhary N., Chelis I., Chomiczewska A., Coenen J. W., Cole M., Cordella F., Corre Y., Crombe K., Cseh G., Csillag B., Damm H., Day C., de Baar M., De la Cal E., Degenkolbe S., Demby A., Denk S., Dhard C., Di Siena A., Dinklage A., Dittmar T., Dreval M., Drevlak M., Drewelow P., Drews P., Dunai D., Edlund E., Effenberg F., Ehrke G., Endler M., Ennis D. A., Escoto F. J., Estrada T., Fable E., Fahrenkamp N., Fanni A., Faustin J., Fellinger J., Feng Y., Figacz W., Flom E., Ford O., Fornal T., Frerichs H., Freundt S., Fuchert G., Fukuyama M., Fullenbach F., Gantenbein G., Gao Y., Garcia K., Regana J. M. G., Garcia-Cortes I., Gaspar J., Gates D. A., Geiger J., Geiger B., Giudicotti L., Gonzalez A., Goriaev A., Gradic D., Grahl M., Graves J. P., Green J., Grelier E., Greuner H., Gross S., Grote H., Groth M., Gruca M., Grulke O., Grun M., Arnaiz J. G., Gunter S., Haak V., Haas M., Hacker P., Hakola A., Hallenbert A., Hammond K., Han X., Hansen S. K., Harris J. H., Hartfuss H., Hartmann D., Hathiramani D., Hatzky R., Hawke J., Hegedus S., Hein B., Heinemann B., Helander P., Henneberg S., Hergenhahn U., Hidalgo C., Hindenlang F., Hirsch M., Hofel U., Hollfeld K. P., Holtz A., Hopf D., Hoschen D., Houry M., Howard J., Huang X., Hubeny M., Hudson S., Ida K., Igitkhanov Y., Igochine V., Illy S., Ionita-Schrittwieser C., Isobe M., Jablczynska M., Jablonski S., Jagielski B., Jakubowski M., van Vuuren A. J., Jelonnek J., Jenko F., Jensen T., Jenzsch H., Junghanns P., Kaczmarczyk J., Kallmeyer J., Kamionka U., Kandler M., Kasilov S., Kazakov Y., Kennedy D., Kharwandikar A., Khokhlov M., Kiefer C., Killer C., Kirschner A., Kleiber R., Klinger T., Klose S., Knauer J., Knieps A., Kochl F., Kocsis G., Kolesnichenko Ya. I., Konies A., Konig R., Kontula J., Kornejew P., Koschinsky J., Kozulia M. M., Kramer-Flecken A., Krampitz R., Krause M., Krawczyk N., Kremeyer T., Krier L., Kriete D. M., Krychowiak M., Ksiazek I., Kubkowska M., Kuczynski M., Kuhner G., Kumar A., Kurki-Suonio T., Kwak S., Landreman M., Lang P. T., Langenberg A., Laqua H. P., Laqua H., Laube R., Lazerson S., Lewerentz M., Li C., Liang Y., Linsmeier Ch., Lion J., Litnovsky A., Liu S., Lobsien J., Loizu J., Lore J., Lorenz A., Losada U., Louche F., Lunsford R., Lutsenko V., Machielsen M., Mackel F., Maisano-Brown J., Maj O., Makowski D., Manduchi G., Maragkoudakis E., Marchuk O., Marsen S., Martines E., Martinez-Fernandez J., Marushchenko M., Masuzaki S., Maurer D., Mayer M., McCarthy K. J., McCormack O., McNeely P., Meister H., Mendelevitch B., Mendes S., Merlo A., Messian A., Mielczarek A., Mishchenko O., Missal B., Mitteau R., Moiseenko V. E., Mollen A., Moncada V., Monnich T., Morisaki T., Moseev D., Motojima G., Mulas S., Mulsow M., Nagel M., Naujoks D., Naulin V., Neelis T., Neilson H., Neu R., Neubauer O., Neuner U., Nicolai D., Nielsen S. K., Niemann H., Nishiza T., Nishizawa T., Nuhrenberg C., Ochoukov R., Oelmann J., Offermanns G., Ogawa K., Okamura S., Olmanns J., Ongena J., Oosterbeek J., Otte M., Pablant N., Alvarez N. P., Pandey A., Pasch E., Pavlichenko R., Pavone A., Pawelec E., Pechstein G., Pelka G., Perseo V., Peterson B., Pilopp D., Pingel S., Pisano F., Plockl B., Plunk G., Poloskei P., Pompe B., Popov A., Porkolab M., Proll J., Pueschel M. J., Puiatti M. -E., Sitjes A. P., Purps F., Rahbarnia K., Rasinski M., Rasmussen J., Reiman A., Reimold F., Reisner M., Reiter D., Richou M., Riedl R., Riemann J., Risse K., Roberg-Clark G., Rohde V., Romazanov J., Rondeshagen D., Rong P., Rudischhauser L., Rummel T., Rummel K., Runov A., Rust N., Ryc L., Salembier P., Salewski M., Sanchez E., Satake S., Satheeswaran G., Schacht J., Scharff E., Schauer F., Schilling J., Schlisio G., Schmid K., Schmitt J., Schmitz O., Schneider W., Schneider M., Schneider P., Schrittwieser R., Schroder T., Schroder M., Schroeder R., Schweer B., Schworer D., Scott E., Shanahan B., Sias G., Sichta P., Singer M., Sinha P., Siplia S., Slaby C., Sleczka M., Smith H., Smoniewski J., Sonnendrucker E., Spolaore M., Spring A., Stadler R., Stanczak D., Stange T., Stepanov I., Stephey L., Stober J., Stroth U., Strumberger E., Suzuki C., Suzuki Y., Svensson J., Szabolics T., Szepesi T., Szucs M., Tabares F. L., Tamura N., Tancetti A., Tantos C., Terry J., Thienpondt H., Thomsen H., Thumm M., Travere J. M., Traverso P., Tretter J., Trier E., Mora H. T., Tsujimura T., Turkin Y., Tykhyi A., Unterberg B., van Eeten P., van Milligen B. Ph., van Schoor M., Vano L., Varoutis S., Vecsei M., Vela L., Velasco J. L., Vervier M., Vianello N., Viebke H., Vilbrandt R., Vogel G., Vogt N., Volkhausen C., von Stechow A., Wagner F., Wang E., Wang H., Warmer F., Wauters T., Wegener L., Wegner T., Weir G., Wenzel U., White A., Wilde F., Wilms F., Windisch T., Winkler M., Winter A., Winters V., Wolf R., Wright A. M., Wurden G. A., Xanthopoulos P., Xu S., Yamada H., Yamaguchi H., Yokoyama M., Yoshinuma M., Yu Q., Zamanov M., Zanini M., Zarnstorff M., Zhang D., Zhou S., Zhu J., Zhu C., Zilker M., Zocco A., Zohm H., Zoletnik S., and Zsuga L.
Abstract: We present recent highlights from the most recent operation phases of Wendelstein 7-X, the most advanced stellarator in the world. Stable detachment with good particle exhaust, low impurity content, and energy confinement times exceeding 100 ms, have been maintained for tens of seconds. Pellet fueling allows for plasma phases with reduced ion-temperature-gradient turbulence, and during such phases, the overall confinement is so good (energy confinement times often exceeding 200 ms) that the attained density and temperature profiles would not have been possible in less optimized devices, since they would have had neoclassical transport losses exceeding the heating applied in W7-X. This provides proof that the reduction of neoclassical transport through magnetic field optimization is successful. W7-X plasmas generally show good impurity screening and high plasma purity, but there is evidence of longer impurity confinement times during turbulence-suppressed phases.
Published: 2022

2. Experimental confirmation of efficient island divertor operation and successful neoclassical transport optimization in Wendelstein 7-X

Author: Pedersen, T, Abramovic, I, Agostinetti, P, Torres, M, Akaslompolo, S, Belloso, J, Aleynikov, P, Aleynikova, K, Alhashimi, M, Ali, A, Allen, N, Alonso, A, Anda, G, Andreeva, T, Angioni, C, Arkhipov, A, Arnold, A, Asad, W, Ascasibar, E, Aumeunier, M, Avramidis, K, Aymerich, E, Baek, S, Bahner, J, Baillod, A, Balden, M, Baldzuhn, J, Ballinger, S, Banduch, M, Bannmann, S, Navarro, A, Barbui, T, Beidler, C, Belafdil, C, Bencze, A, Benndorf, A, Beurskens, M, Biedermann, C, Biletskyi, O, Blackwell, B, Blatzheim, M, Bluhm, T, Bockenhoff, D, Bongiovi, G, Borchardt, M, Borodin, D, Boscary, J, Bosch, H, Bosmann, T, Boswirth, B, Bottger, L, Bottino, A, Bozhenkov, S, Brakel, R, Brandt, C, Brauer, T, Braune, H, Brezinsek, S, Brunner, K, Buller, S, Burhenn, R, Bussiahn, R, Buttenschon, B, Buzas, A, Bykov, V, Calvo, I, Mata, K, Caminal, I, Cannas, B, Cappa, A, Carls, A, Carovani, F, Carr, M, Carralero, D, Carvalho, B, Casas, J, Castano-Bardawil, D, Castejon, F, Chaudhary, N, Chelis, I, Chomiczewska, A, Coenen, J, Cole, M, Cordella, F, Corre, Y, Crombe, K, Cseh, G, Csillag, B, Damm, H, Day, C, de Baar, M, De la Cal, E, Degenkolbe, S, Demby, A, Denk, S, Dhard, C, Di Siena, A, Dinklage, A, Dittmar, T, Dreval, M, Drevlak, M, Drewelow, P, Drews, P, Dunai, D, Edlund, E, Effenberg, F, Ehrke, G, Endler, M, Ennis, D, Escoto, F, Estrada, T, Fable, E, Fahrenkamp, N, Fanni, A, Faustin, J, Fellinger, J, Feng, Y, Figacz, W, Flom, E, Ford, O, Fornal, T, Frerichs, H, Freundt, S, Fuchert, G, Fukuyama, M, Fullenbach, F, Gantenbein, G, Gao, Y, Garcia, K, Regana, J, Garcia-Cortes, I, Gaspar, J, Gates, D, Geiger, J, Geiger, B, Giudicotti, L, Gonzalez, A, Goriaev, A, Gradic, D, Grahl, M, Graves, J, Green, J, Grelier, E, Greuner, H, Gross, S, Grote, H, Groth, M, Gruca, M, Grulke, O, Grun, M, Arnaiz, J, Gunter, S, Haak, V, Haas, M, Hacker, P, Hakola, A, Hallenbert, A, Hammond, K, Han, X, Hansen, S, Harris, J, Hartfuss, H, Hartmann, D, Hathiramani, D, Hatzky, R, Hawke, J, Hegedus, S, Hein, B, Heinemann, B, Helander, P, Henneberg, S, Hergenhahn, U, Hidalgo, C, Hindenlang, F, Hirsch, M, Hofel, U, Hollfeld, K, Holtz, A, Hopf, D, Hoschen, D, Houry, M, Howard, J, Huang, X, Hubeny, M, Hudson, S, Ida, K, Igitkhanov, Y, Igochine, V, Illy, S, Ionita-Schrittwieser, C, Isobe, M, Jablczynska, M, Jablonski, S, Jagielski, B, Jakubowski, M, van Vuuren, A, Jelonnek, J, Jenko, F, Jensen, T, Jenzsch, H, Junghanns, P, Kaczmarczyk, J, Kallmeyer, J, Kamionka, U, Kandler, M, Kasilov, S, Kazakov, Y, Kennedy, D, Kharwandikar, A, Khokhlov, M, Kiefer, C, Killer, C, Kirschner, A, Kleiber, R, Klinger, T, Klose, S, Knauer, J, Knieps, A, Kochl, F, Kocsis, G, Kolesnichenko, Y, Konies, A, Konig, R, Kontula, J, Kornejew, P, Koschinsky, J, Kozulia, M, Kramer-Flecken, A, Krampitz, R, Krause, M, Krawczyk, N, Kremeyer, T, Krier, L, Kriete, D, Krychowiak, M, Ksiazek, I, Kubkowska, M, Kuczynski, M, Kuhner, G, Kumar, A, Kurki-Suonio, T, Kwak, S, Landreman, M, Lang, P, Langenberg, A, Laqua, H, Laube, R, Lazerson, S, Lewerentz, M, Li, C, Liang, Y, Linsmeier, C, Lion, J, Litnovsky, A, Liu, S, Lobsien, J, Loizu, J, Lore, J, Lorenz, A, Losada, U, Louche, F, Lunsford, R, Lutsenko, V, Machielsen, M, Mackel, F, Maisano-Brown, J, Maj, O, Makowski, D, Manduchi, G, Maragkoudakis, E, Marchuk, O, Marsen, S, Martines, E, Martinez-Fernandez, J, Marushchenko, M, Masuzaki, S, Maurer, D, Mayer, M, Mccarthy, K, Mccormack, O, Mcneely, P, Meister, H, Mendelevitch, B, Mendes, S, Merlo, A, Messian, A, Mielczarek, A, Mishchenko, O, Missal, B, Mitteau, R, Moiseenko, V, Mollen, A, Moncada, V, Monnich, T, Morisaki, T, Moseev, D, Motojima, G, Mulas, S, Mulsow, M, Nagel, M, Naujoks, D, Naulin, V, Neelis, T, Neilson, H, Neu, R, Neubauer, O, Neuner, U, Nicolai, D, Nielsen, S, Niemann, H, Nishiza, T, Nishizawa, T, Nuhrenberg, C, Ochoukov, R, Oelmann, J, Offermanns, G, Ogawa, K, Okamura, S, Olmanns, J, Ongena, J, Oosterbeek, J, Otte, M, Pablant, N, Alvarez, N, Pandey, A, Pasch, E, Pavlichenko, R, Pavone, A, Pawelec, E, Pechstein, G, Pelka, G, Perseo, V, Peterson, B, Pilopp, D, Pingel, S, Pisano, F, Plockl, B, Plunk, G, Poloskei, P, Pompe, B, Popov, A, Porkolab, M, Proll, J, Pueschel, M, Puiatti, M, Sitjes, A, Purps, F, Rahbarnia, K, Rasinski, M, Rasmussen, J, Reiman, A, Reimold, F, Reisner, M, Reiter, D, Richou, M, Riedl, R, Riemann, J, Risse, K, Roberg-Clark, G, Rohde, V, Romazanov, J, Rondeshagen, D, Rong, P, Rudischhauser, L, Rummel, T, Rummel, K, Runov, A, Rust, N, Ryc, L, Salembier, P, Salewski, M, Sanchez, E, Satake, S, Satheeswaran, G, Schacht, J, Scharff, E, Schauer, F, Schilling, J, Schlisio, G, Schmid, K, Schmitt, J, Schmitz, O, Schneider, W, Schneider, M, Schneider, P, Schrittwieser, R, Schroder, T, Schroder, M, Schroeder, R, Schweer, B, Schworer, D, Scott, E, Shanahan, B, Sias, G, Sichta, P, Singer, M, Sinha, P, Siplia, S, Slaby, C, Sleczka, M, Smith, H, Smoniewski, J, Sonnendrucker, E, Spolaore, M, Spring, A, Stadler, R, Stanczak, D, Stange, T, Stepanov, I, Stephey, L, Stober, J, Stroth, U, Strumberger, E, Suzuki, C, Suzuki, Y, Svensson, J, Szabolics, T, Szepesi, T, Szucs, M, Tabares, F, Tamura, N, Tancetti, A, Tantos, C, Terry, J, Thienpondt, H, Thomsen, H, Thumm, M, Travere, J, Traverso, P, Tretter, J, Trier, E, Mora, H, Tsujimura, T, Turkin, Y, Tykhyi, A, Unterberg, B, van Eeten, P, van Milligen, B, van Schoor, M, Vano, L, Varoutis, S, Vecsei, M, Vela, L, Velasco, J, Vervier, M, Vianello, N, Viebke, H, Vilbrandt, R, Vogel, G, Vogt, N, Volkhausen, C, von Stechow, A, Wagner, F, Wang, E, Wang, H, Warmer, F, Wauters, T, Wegener, L, Wegner, T, Weir, G, Wenzel, U, White, A, Wilde, F, Wilms, F, Windisch, T, Winkler, M, Winter, A, Winters, V, Wolf, R, Wright, A, Wurden, G, Xanthopoulos, P, Xu, S, Yamada, H, Yamaguchi, H, Yokoyama, M, Yoshinuma, M, Yu, Q, Zamanov, M, Zanini, M, Zarnstorff, M, Zhang, D, Zhou, S, Zhu, J, Zhu, C, Zilker, M, Zocco, A, Zohm, H, Zoletnik, S, Zsuga, L, Pedersen T. S., Abramovic I., Agostinetti P., Torres M. A., Akaslompolo S., Belloso J. A., Aleynikov P., Aleynikova K., Alhashimi M., Ali A., Allen N., Alonso A., Anda G., Andreeva T., Angioni C., Arkhipov A., Arnold A., Asad W., Ascasibar E., Aumeunier M. -H., Avramidis K., Aymerich E., Baek S. -G., Bahner J., Baillod A., Balden M., Baldzuhn J., Ballinger S., Banduch M., Bannmann S., Navarro A. B., Barbui T., Beidler C., Belafdil C., Bencze A., Benndorf A., Beurskens M., Biedermann C., Biletskyi O., Blackwell B., Blatzheim M., Bluhm T., Bockenhoff D., Bongiovi G., Borchardt M., Borodin D., Boscary J., Bosch H., Bosmann T., Boswirth B., Bottger L., Bottino A., Bozhenkov S., Brakel R., Brandt C., Brauer T., Braune H., Brezinsek S., Brunner K., Buller S., Burhenn R., Bussiahn R., Buttenschon B., Buzas A., Bykov V., Calvo I., Mata K. C., Caminal I., Cannas B., Cappa A., Carls A., Carovani F., Carr M., Carralero D., Carvalho B., Casas J., Castano-Bardawil D., Castejon F., Chaudhary N., Chelis I., Chomiczewska A., Coenen J. W., Cole M., Cordella F., Corre Y., Crombe K., Cseh G., Csillag B., Damm H., Day C., de Baar M., De la Cal E., Degenkolbe S., Demby A., Denk S., Dhard C., Di Siena A., Dinklage A., Dittmar T., Dreval M., Drevlak M., Drewelow P., Drews P., Dunai D., Edlund E., Effenberg F., Ehrke G., Endler M., Ennis D. A., Escoto F. J., Estrada T., Fable E., Fahrenkamp N., Fanni A., Faustin J., Fellinger J., Feng Y., Figacz W., Flom E., Ford O., Fornal T., Frerichs H., Freundt S., Fuchert G., Fukuyama M., Fullenbach F., Gantenbein G., Gao Y., Garcia K., Regana J. M. G., Garcia-Cortes I., Gaspar J., Gates D. A., Geiger J., Geiger B., Giudicotti L., Gonzalez A., Goriaev A., Gradic D., Grahl M., Graves J. P., Green J., Grelier E., Greuner H., Gross S., Grote H., Groth M., Gruca M., Grulke O., Grun M., Arnaiz J. G., Gunter S., Haak V., Haas M., Hacker P., Hakola A., Hallenbert A., Hammond K., Han X., Hansen S. K., Harris J. H., Hartfuss H., Hartmann D., Hathiramani D., Hatzky R., Hawke J., Hegedus S., Hein B., Heinemann B., Helander P., Henneberg S., Hergenhahn U., Hidalgo C., Hindenlang F., Hirsch M., Hofel U., Hollfeld K. P., Holtz A., Hopf D., Hoschen D., Houry M., Howard J., Huang X., Hubeny M., Hudson S., Ida K., Igitkhanov Y., Igochine V., Illy S., Ionita-Schrittwieser C., Isobe M., Jablczynska M., Jablonski S., Jagielski B., Jakubowski M., van Vuuren A. J., Jelonnek J., Jenko F., Jensen T., Jenzsch H., Junghanns P., Kaczmarczyk J., Kallmeyer J., Kamionka U., Kandler M., Kasilov S., Kazakov Y., Kennedy D., Kharwandikar A., Khokhlov M., Kiefer C., Killer C., Kirschner A., Kleiber R., Klinger T., Klose S., Knauer J., Knieps A., Kochl F., Kocsis G., Kolesnichenko Ya. I., Konies A., Konig R., Kontula J., Kornejew P., Koschinsky J., Kozulia M. M., Kramer-Flecken A., Krampitz R., Krause M., Krawczyk N., Kremeyer T., Krier L., Kriete D. M., Krychowiak M., Ksiazek I., Kubkowska M., Kuczynski M., Kuhner G., Kumar A., Kurki-Suonio T., Kwak S., Landreman M., Lang P. T., Langenberg A., Laqua H. P., Laqua H., Laube R., Lazerson S., Lewerentz M., Li C., Liang Y., Linsmeier Ch., Lion J., Litnovsky A., Liu S., Lobsien J., Loizu J., Lore J., Lorenz A., Losada U., Louche F., Lunsford R., Lutsenko V., Machielsen M., Mackel F., Maisano-Brown J., Maj O., Makowski D., Manduchi G., Maragkoudakis E., Marchuk O., Marsen S., Martines E., Martinez-Fernandez J., Marushchenko M., Masuzaki S., Maurer D., Mayer M., McCarthy K. J., McCormack O., McNeely P., Meister H., Mendelevitch B., Mendes S., Merlo A., Messian A., Mielczarek A., Mishchenko O., Missal B., Mitteau R., Moiseenko V. E., Mollen A., Moncada V., Monnich T., Morisaki T., Moseev D., Motojima G., Mulas S., Mulsow M., Nagel M., Naujoks D., Naulin V., Neelis T., Neilson H., Neu R., Neubauer O., Neuner U., Nicolai D., Nielsen S. K., Niemann H., Nishiza T., Nishizawa T., Nuhrenberg C., Ochoukov R., Oelmann J., Offermanns G., Ogawa K., Okamura S., Olmanns J., Ongena J., Oosterbeek J., Otte M., Pablant N., Alvarez N. P., Pandey A., Pasch E., Pavlichenko R., Pavone A., Pawelec E., Pechstein G., Pelka G., Perseo V., Peterson B., Pilopp D., Pingel S., Pisano F., Plockl B., Plunk G., Poloskei P., Pompe B., Popov A., Porkolab M., Proll J., Pueschel M. J., Puiatti M. -E., Sitjes A. P., Purps F., Rahbarnia K., Rasinski M., Rasmussen J., Reiman A., Reimold F., Reisner M., Reiter D., Richou M., Riedl R., Riemann J., Risse K., Roberg-Clark G., Rohde V., Romazanov J., Rondeshagen D., Rong P., Rudischhauser L., Rummel T., Rummel K., Runov A., Rust N., Ryc L., Salembier P., Salewski M., Sanchez E., Satake S., Satheeswaran G., Schacht J., Scharff E., Schauer F., Schilling J., Schlisio G., Schmid K., Schmitt J., Schmitz O., Schneider W., Schneider M., Schneider P., Schrittwieser R., Schroder T., Schroder M., Schroeder R., Schweer B., Schworer D., Scott E., Shanahan B., Sias G., Sichta P., Singer M., Sinha P., Siplia S., Slaby C., Sleczka M., Smith H., Smoniewski J., Sonnendrucker E., Spolaore M., Spring A., Stadler R., Stanczak D., Stange T., Stepanov I., Stephey L., Stober J., Stroth U., Strumberger E., Suzuki C., Suzuki Y., Svensson J., Szabolics T., Szepesi T., Szucs M., Tabares F. L., Tamura N., Tancetti A., Tantos C., Terry J., Thienpondt H., Thomsen H., Thumm M., Travere J. M., Traverso P., Tretter J., Trier E., Mora H. T., Tsujimura T., Turkin Y., Tykhyi A., Unterberg B., van Eeten P., van Milligen B. Ph., van Schoor M., Vano L., Varoutis S., Vecsei M., Vela L., Velasco J. L., Vervier M., Vianello N., Viebke H., Vilbrandt R., Vogel G., Vogt N., Volkhausen C., von Stechow A., Wagner F., Wang E., Wang H., Warmer F., Wauters T., Wegener L., Wegner T., Weir G., Wenzel U., White A., Wilde F., Wilms F., Windisch T., Winkler M., Winter A., Winters V., Wolf R., Wright A. M., Wurden G. A., Xanthopoulos P., Xu S., Yamada H., Yamaguchi H., Yokoyama M., Yoshinuma M., Yu Q., Zamanov M., Zanini M., Zarnstorff M., Zhang D., Zhou S., Zhu J., Zhu C., Zilker M., Zocco A., Zohm H., Zoletnik S., Zsuga L., Pedersen, T, Abramovic, I, Agostinetti, P, Torres, M, Akaslompolo, S, Belloso, J, Aleynikov, P, Aleynikova, K, Alhashimi, M, Ali, A, Allen, N, Alonso, A, Anda, G, Andreeva, T, Angioni, C, Arkhipov, A, Arnold, A, Asad, W, Ascasibar, E, Aumeunier, M, Avramidis, K, Aymerich, E, Baek, S, Bahner, J, Baillod, A, Balden, M, Baldzuhn, J, Ballinger, S, Banduch, M, Bannmann, S, Navarro, A, Barbui, T, Beidler, C, Belafdil, C, Bencze, A, Benndorf, A, Beurskens, M, Biedermann, C, Biletskyi, O, Blackwell, B, Blatzheim, M, Bluhm, T, Bockenhoff, D, Bongiovi, G, Borchardt, M, Borodin, D, Boscary, J, Bosch, H, Bosmann, T, Boswirth, B, Bottger, L, Bottino, A, Bozhenkov, S, Brakel, R, Brandt, C, Brauer, T, Braune, H, Brezinsek, S, Brunner, K, Buller, S, Burhenn, R, Bussiahn, R, Buttenschon, B, Buzas, A, Bykov, V, Calvo, I, Mata, K, Caminal, I, Cannas, B, Cappa, A, Carls, A, Carovani, F, Carr, M, Carralero, D, Carvalho, B, Casas, J, Castano-Bardawil, D, Castejon, F, Chaudhary, N, Chelis, I, Chomiczewska, A, Coenen, J, Cole, M, Cordella, F, Corre, Y, Crombe, K, Cseh, G, Csillag, B, Damm, H, Day, C, de Baar, M, De la Cal, E, Degenkolbe, S, Demby, A, Denk, S, Dhard, C, Di Siena, A, Dinklage, A, Dittmar, T, Dreval, M, Drevlak, M, Drewelow, P, Drews, P, Dunai, D, Edlund, E, Effenberg, F, Ehrke, G, Endler, M, Ennis, D, Escoto, F, Estrada, T, Fable, E, Fahrenkamp, N, Fanni, A, Faustin, J, Fellinger, J, Feng, Y, Figacz, W, Flom, E, Ford, O, Fornal, T, Frerichs, H, Freundt, S, Fuchert, G, Fukuyama, M, Fullenbach, F, Gantenbein, G, Gao, Y, Garcia, K, Regana, J, Garcia-Cortes, I, Gaspar, J, Gates, D, Geiger, J, Geiger, B, Giudicotti, L, Gonzalez, A, Goriaev, A, Gradic, D, Grahl, M, Graves, J, Green, J, Grelier, E, Greuner, H, Gross, S, Grote, H, Groth, M, Gruca, M, Grulke, O, Grun, M, Arnaiz, J, Gunter, S, Haak, V, Haas, M, Hacker, P, Hakola, A, Hallenbert, A, Hammond, K, Han, X, Hansen, S, Harris, J, Hartfuss, H, Hartmann, D, Hathiramani, D, Hatzky, R, Hawke, J, Hegedus, S, Hein, B, Heinemann, B, Helander, P, Henneberg, S, Hergenhahn, U, Hidalgo, C, Hindenlang, F, Hirsch, M, Hofel, U, Hollfeld, K, Holtz, A, Hopf, D, Hoschen, D, Houry, M, Howard, J, Huang, X, Hubeny, M, Hudson, S, Ida, K, Igitkhanov, Y, Igochine, V, Illy, S, Ionita-Schrittwieser, C, Isobe, M, Jablczynska, M, Jablonski, S, Jagielski, B, Jakubowski, M, van Vuuren, A, Jelonnek, J, Jenko, F, Jensen, T, Jenzsch, H, Junghanns, P, Kaczmarczyk, J, Kallmeyer, J, Kamionka, U, Kandler, M, Kasilov, S, Kazakov, Y, Kennedy, D, Kharwandikar, A, Khokhlov, M, Kiefer, C, Killer, C, Kirschner, A, Kleiber, R, Klinger, T, Klose, S, Knauer, J, Knieps, A, Kochl, F, Kocsis, G, Kolesnichenko, Y, Konies, A, Konig, R, Kontula, J, Kornejew, P, Koschinsky, J, Kozulia, M, Kramer-Flecken, A, Krampitz, R, Krause, M, Krawczyk, N, Kremeyer, T, Krier, L, Kriete, D, Krychowiak, M, Ksiazek, I, Kubkowska, M, Kuczynski, M, Kuhner, G, Kumar, A, Kurki-Suonio, T, Kwak, S, Landreman, M, Lang, P, Langenberg, A, Laqua, H, Laube, R, Lazerson, S, Lewerentz, M, Li, C, Liang, Y, Linsmeier, C, Lion, J, Litnovsky, A, Liu, S, Lobsien, J, Loizu, J, Lore, J, Lorenz, A, Losada, U, Louche, F, Lunsford, R, Lutsenko, V, Machielsen, M, Mackel, F, Maisano-Brown, J, Maj, O, Makowski, D, Manduchi, G, Maragkoudakis, E, Marchuk, O, Marsen, S, Martines, E, Martinez-Fernandez, J, Marushchenko, M, Masuzaki, S, Maurer, D, Mayer, M, Mccarthy, K, Mccormack, O, Mcneely, P, Meister, H, Mendelevitch, B, Mendes, S, Merlo, A, Messian, A, Mielczarek, A, Mishchenko, O, Missal, B, Mitteau, R, Moiseenko, V, Mollen, A, Moncada, V, Monnich, T, Morisaki, T, Moseev, D, Motojima, G, Mulas, S, Mulsow, M, Nagel, M, Naujoks, D, Naulin, V, Neelis, T, Neilson, H, Neu, R, Neubauer, O, Neuner, U, Nicolai, D, Nielsen, S, Niemann, H, Nishiza, T, Nishizawa, T, Nuhrenberg, C, Ochoukov, R, Oelmann, J, Offermanns, G, Ogawa, K, Okamura, S, Olmanns, J, Ongena, J, Oosterbeek, J, Otte, M, Pablant, N, Alvarez, N, Pandey, A, Pasch, E, Pavlichenko, R, Pavone, A, Pawelec, E, Pechstein, G, Pelka, G, Perseo, V, Peterson, B, Pilopp, D, Pingel, S, Pisano, F, Plockl, B, Plunk, G, Poloskei, P, Pompe, B, Popov, A, Porkolab, M, Proll, J, Pueschel, M, Puiatti, M, Sitjes, A, Purps, F, Rahbarnia, K, Rasinski, M, Rasmussen, J, Reiman, A, Reimold, F, Reisner, M, Reiter, D, Richou, M, Riedl, R, Riemann, J, Risse, K, Roberg-Clark, G, Rohde, V, Romazanov, J, Rondeshagen, D, Rong, P, Rudischhauser, L, Rummel, T, Rummel, K, Runov, A, Rust, N, Ryc, L, Salembier, P, Salewski, M, Sanchez, E, Satake, S, Satheeswaran, G, Schacht, J, Scharff, E, Schauer, F, Schilling, J, Schlisio, G, Schmid, K, Schmitt, J, Schmitz, O, Schneider, W, Schneider, M, Schneider, P, Schrittwieser, R, Schroder, T, Schroder, M, Schroeder, R, Schweer, B, Schworer, D, Scott, E, Shanahan, B, Sias, G, Sichta, P, Singer, M, Sinha, P, Siplia, S, Slaby, C, Sleczka, M, Smith, H, Smoniewski, J, Sonnendrucker, E, Spolaore, M, Spring, A, Stadler, R, Stanczak, D, Stange, T, Stepanov, I, Stephey, L, Stober, J, Stroth, U, Strumberger, E, Suzuki, C, Suzuki, Y, Svensson, J, Szabolics, T, Szepesi, T, Szucs, M, Tabares, F, Tamura, N, Tancetti, A, Tantos, C, Terry, J, Thienpondt, H, Thomsen, H, Thumm, M, Travere, J, Traverso, P, Tretter, J, Trier, E, Mora, H, Tsujimura, T, Turkin, Y, Tykhyi, A, Unterberg, B, van Eeten, P, van Milligen, B, van Schoor, M, Vano, L, Varoutis, S, Vecsei, M, Vela, L, Velasco, J, Vervier, M, Vianello, N, Viebke, H, Vilbrandt, R, Vogel, G, Vogt, N, Volkhausen, C, von Stechow, A, Wagner, F, Wang, E, Wang, H, Warmer, F, Wauters, T, Wegener, L, Wegner, T, Weir, G, Wenzel, U, White, A, Wilde, F, Wilms, F, Windisch, T, Winkler, M, Winter, A, Winters, V, Wolf, R, Wright, A, Wurden, G, Xanthopoulos, P, Xu, S, Yamada, H, Yamaguchi, H, Yokoyama, M, Yoshinuma, M, Yu, Q, Zamanov, M, Zanini, M, Zarnstorff, M, Zhang, D, Zhou, S, Zhu, J, Zhu, C, Zilker, M, Zocco, A, Zohm, H, Zoletnik, S, Zsuga, L, Pedersen T. S., Abramovic I., Agostinetti P., Torres M. A., Akaslompolo S., Belloso J. A., Aleynikov P., Aleynikova K., Alhashimi M., Ali A., Allen N., Alonso A., Anda G., Andreeva T., Angioni C., Arkhipov A., Arnold A., Asad W., Ascasibar E., Aumeunier M. -H., Avramidis K., Aymerich E., Baek S. -G., Bahner J., Baillod A., Balden M., Baldzuhn J., Ballinger S., Banduch M., Bannmann S., Navarro A. B., Barbui T., Beidler C., Belafdil C., Bencze A., Benndorf A., Beurskens M., Biedermann C., Biletskyi O., Blackwell B., Blatzheim M., Bluhm T., Bockenhoff D., Bongiovi G., Borchardt M., Borodin D., Boscary J., Bosch H., Bosmann T., Boswirth B., Bottger L., Bottino A., Bozhenkov S., Brakel R., Brandt C., Brauer T., Braune H., Brezinsek S., Brunner K., Buller S., Burhenn R., Bussiahn R., Buttenschon B., Buzas A., Bykov V., Calvo I., Mata K. C., Caminal I., Cannas B., Cappa A., Carls A., Carovani F., Carr M., Carralero D., Carvalho B., Casas J., Castano-Bardawil D., Castejon F., Chaudhary N., Chelis I., Chomiczewska A., Coenen J. W., Cole M., Cordella F., Corre Y., Crombe K., Cseh G., Csillag B., Damm H., Day C., de Baar M., De la Cal E., Degenkolbe S., Demby A., Denk S., Dhard C., Di Siena A., Dinklage A., Dittmar T., Dreval M., Drevlak M., Drewelow P., Drews P., Dunai D., Edlund E., Effenberg F., Ehrke G., Endler M., Ennis D. A., Escoto F. J., Estrada T., Fable E., Fahrenkamp N., Fanni A., Faustin J., Fellinger J., Feng Y., Figacz W., Flom E., Ford O., Fornal T., Frerichs H., Freundt S., Fuchert G., Fukuyama M., Fullenbach F., Gantenbein G., Gao Y., Garcia K., Regana J. M. G., Garcia-Cortes I., Gaspar J., Gates D. A., Geiger J., Geiger B., Giudicotti L., Gonzalez A., Goriaev A., Gradic D., Grahl M., Graves J. P., Green J., Grelier E., Greuner H., Gross S., Grote H., Groth M., Gruca M., Grulke O., Grun M., Arnaiz J. G., Gunter S., Haak V., Haas M., Hacker P., Hakola A., Hallenbert A., Hammond K., Han X., Hansen S. K., Harris J. H., Hartfuss H., Hartmann D., Hathiramani D., Hatzky R., Hawke J., Hegedus S., Hein B., Heinemann B., Helander P., Henneberg S., Hergenhahn U., Hidalgo C., Hindenlang F., Hirsch M., Hofel U., Hollfeld K. P., Holtz A., Hopf D., Hoschen D., Houry M., Howard J., Huang X., Hubeny M., Hudson S., Ida K., Igitkhanov Y., Igochine V., Illy S., Ionita-Schrittwieser C., Isobe M., Jablczynska M., Jablonski S., Jagielski B., Jakubowski M., van Vuuren A. J., Jelonnek J., Jenko F., Jensen T., Jenzsch H., Junghanns P., Kaczmarczyk J., Kallmeyer J., Kamionka U., Kandler M., Kasilov S., Kazakov Y., Kennedy D., Kharwandikar A., Khokhlov M., Kiefer C., Killer C., Kirschner A., Kleiber R., Klinger T., Klose S., Knauer J., Knieps A., Kochl F., Kocsis G., Kolesnichenko Ya. I., Konies A., Konig R., Kontula J., Kornejew P., Koschinsky J., Kozulia M. M., Kramer-Flecken A., Krampitz R., Krause M., Krawczyk N., Kremeyer T., Krier L., Kriete D. M., Krychowiak M., Ksiazek I., Kubkowska M., Kuczynski M., Kuhner G., Kumar A., Kurki-Suonio T., Kwak S., Landreman M., Lang P. T., Langenberg A., Laqua H. P., Laqua H., Laube R., Lazerson S., Lewerentz M., Li C., Liang Y., Linsmeier Ch., Lion J., Litnovsky A., Liu S., Lobsien J., Loizu J., Lore J., Lorenz A., Losada U., Louche F., Lunsford R., Lutsenko V., Machielsen M., Mackel F., Maisano-Brown J., Maj O., Makowski D., Manduchi G., Maragkoudakis E., Marchuk O., Marsen S., Martines E., Martinez-Fernandez J., Marushchenko M., Masuzaki S., Maurer D., Mayer M., McCarthy K. J., McCormack O., McNeely P., Meister H., Mendelevitch B., Mendes S., Merlo A., Messian A., Mielczarek A., Mishchenko O., Missal B., Mitteau R., Moiseenko V. E., Mollen A., Moncada V., Monnich T., Morisaki T., Moseev D., Motojima G., Mulas S., Mulsow M., Nagel M., Naujoks D., Naulin V., Neelis T., Neilson H., Neu R., Neubauer O., Neuner U., Nicolai D., Nielsen S. K., Niemann H., Nishiza T., Nishizawa T., Nuhrenberg C., Ochoukov R., Oelmann J., Offermanns G., Ogawa K., Okamura S., Olmanns J., Ongena J., Oosterbeek J., Otte M., Pablant N., Alvarez N. P., Pandey A., Pasch E., Pavlichenko R., Pavone A., Pawelec E., Pechstein G., Pelka G., Perseo V., Peterson B., Pilopp D., Pingel S., Pisano F., Plockl B., Plunk G., Poloskei P., Pompe B., Popov A., Porkolab M., Proll J., Pueschel M. J., Puiatti M. -E., Sitjes A. P., Purps F., Rahbarnia K., Rasinski M., Rasmussen J., Reiman A., Reimold F., Reisner M., Reiter D., Richou M., Riedl R., Riemann J., Risse K., Roberg-Clark G., Rohde V., Romazanov J., Rondeshagen D., Rong P., Rudischhauser L., Rummel T., Rummel K., Runov A., Rust N., Ryc L., Salembier P., Salewski M., Sanchez E., Satake S., Satheeswaran G., Schacht J., Scharff E., Schauer F., Schilling J., Schlisio G., Schmid K., Schmitt J., Schmitz O., Schneider W., Schneider M., Schneider P., Schrittwieser R., Schroder T., Schroder M., Schroeder R., Schweer B., Schworer D., Scott E., Shanahan B., Sias G., Sichta P., Singer M., Sinha P., Siplia S., Slaby C., Sleczka M., Smith H., Smoniewski J., Sonnendrucker E., Spolaore M., Spring A., Stadler R., Stanczak D., Stange T., Stepanov I., Stephey L., Stober J., Stroth U., Strumberger E., Suzuki C., Suzuki Y., Svensson J., Szabolics T., Szepesi T., Szucs M., Tabares F. L., Tamura N., Tancetti A., Tantos C., Terry J., Thienpondt H., Thomsen H., Thumm M., Travere J. M., Traverso P., Tretter J., Trier E., Mora H. T., Tsujimura T., Turkin Y., Tykhyi A., Unterberg B., van Eeten P., van Milligen B. Ph., van Schoor M., Vano L., Varoutis S., Vecsei M., Vela L., Velasco J. L., Vervier M., Vianello N., Viebke H., Vilbrandt R., Vogel G., Vogt N., Volkhausen C., von Stechow A., Wagner F., Wang E., Wang H., Warmer F., Wauters T., Wegener L., Wegner T., Weir G., Wenzel U., White A., Wilde F., Wilms F., Windisch T., Winkler M., Winter A., Winters V., Wolf R., Wright A. M., Wurden G. A., Xanthopoulos P., Xu S., Yamada H., Yamaguchi H., Yokoyama M., Yoshinuma M., Yu Q., Zamanov M., Zanini M., Zarnstorff M., Zhang D., Zhou S., Zhu J., Zhu C., Zilker M., Zocco A., Zohm H., Zoletnik S., and Zsuga L.
Abstract: We present recent highlights from the most recent operation phases of Wendelstein 7-X, the most advanced stellarator in the world. Stable detachment with good particle exhaust, low impurity content, and energy confinement times exceeding 100 ms, have been maintained for tens of seconds. Pellet fueling allows for plasma phases with reduced ion-temperature-gradient turbulence, and during such phases, the overall confinement is so good (energy confinement times often exceeding 200 ms) that the attained density and temperature profiles would not have been possible in less optimized devices, since they would have had neoclassical transport losses exceeding the heating applied in W7-X. This provides proof that the reduction of neoclassical transport through magnetic field optimization is successful. W7-X plasmas generally show good impurity screening and high plasma purity, but there is evidence of longer impurity confinement times during turbulence-suppressed phases.
Published: 2022

3. An Updated View of the Water Masses on the Northeast Greenland Shelf and Their Link to the Laptev Sea and Lena River

Author: Willcox, E. W., Bendtsen, J., Mortensen, J., Mohn, C., Lemes, M., Pedersen, T. J., Holding, J., Møller, E. F., Sejr, M. K., Seidenkrantz, M.-S., Rysgaard, S., Willcox, E. W., Bendtsen, J., Mortensen, J., Mohn, C., Lemes, M., Pedersen, T. J., Holding, J., Møller, E. F., Sejr, M. K., Seidenkrantz, M.-S., and Rysgaard, S.
Published: 2023

4. An Updated View of the Water Masses on the Northeast Greenland Shelf and Their Link to the Laptev Sea and Lena River

Author: Willcox, E. W., Bendtsen, J., Mortensen, J., Mohn, C., Lemes, M., Pedersen, T. J., Holding, J., Møller, E. F., Sejr, M. K., Seidenkrantz, M.-S., Rysgaard, S., Willcox, E. W., Bendtsen, J., Mortensen, J., Mohn, C., Lemes, M., Pedersen, T. J., Holding, J., Møller, E. F., Sejr, M. K., Seidenkrantz, M.-S., and Rysgaard, S.
Published: 2023

5. Influence of glacier type on bloom phenology in two Southwest Greenland fjords

Author: Stuart-Lee, A.E., Mortensen, J., Juul-Pedersen, T., Middelburg, J.j., Soetaert, K., Hopwood, M.j., Engel, A., Meire, L., Stuart-Lee, A.E., Mortensen, J., Juul-Pedersen, T., Middelburg, J.j., Soetaert, K., Hopwood, M.j., Engel, A., and Meire, L.
Abstract: Along Greenland's coastline, the magnitude and timing of primary production in fjords is influenced by meltwater release from marine-terminating glaciers. How local ecosystems will adapt as these glaciers retreat onto land, forcing fundamental changes in hydrography, remains an open question. To further our understanding of this transition, we examine how marine- and land-terminating glaciers respectively influence fjord bloom phenology. Between spring and autumn 2019, we conducted along-fjord transects of hydrographic variables, biogeochemical properties and pico- and nanophytoplankton counts to illustrate the contrasting seasonal bloom dynamics in the fjords Nuup Kangerlua and Ameralik. These fjords are in the same climatic region of west Greenland but influenced by different glacial structures. Nuup Kangerlua, a predominantly marine-terminating system, was differentiated by its sustained second summer bloom and high Chl a fluorescence in summer and autumn. In Ameralik, influenced by a land-terminating glacier, we found higher abundances of pico- and nanophytoplankton, and high cyanobacteria growth in autumn. The summer bloom in Nuup Kangerlua is known to be coincident with subglacial freshwater discharge sustaining renewed nutrient supply to the fjord. We observe here that the intermediate baroclinic circulation, which creates an inflow at subsurface depths, also plays an important role in increasing nutrient availability at shallower depths and potentially explains the distribution of primary producers. Our observations suggest that the retreat of marine-terminating glaciers onto land, with consequent increases in surface water temperature and stratification, and reduced light availability, may alter the magnitude, composition, and distribution of summer productivity.
Published: 2023

6. Electronic stripe patterns near the fermi level of tetragonal Fe(Se,S).

Author: Bötzel, S, Bötzel, S, Zhao, Z, Day, R, Zhdanovich, S, Gorovikov, S, Pedersen, T, Klavins, P, Damascelli, A, Eremin, I, Gozar, A, Scott, K, Boyle, T, da Silva Neto, E, Taufour, Valentin, Walker, Morgan, Byland, Journey, Bötzel, S, Bötzel, S, Zhao, Z, Day, R, Zhdanovich, S, Gorovikov, S, Pedersen, T, Klavins, P, Damascelli, A, Eremin, I, Gozar, A, Scott, K, Boyle, T, da Silva Neto, E, Taufour, Valentin, Walker, Morgan, and Byland, Journey
Abstract: FeSe1-xSx remains one of the most enigmatic systems of Fe-based superconductors. While much is known about the orthorhombic parent compound, FeSe, the tetragonal samples, FeSe1-xSx with x > 0.17, remain relatively unexplored. Here, we provide an in-depth investigation of the electronic states of tetragonal FeSe0.81S0.19, using scanning tunneling microscopy and spectroscopy (STM/S) measurements, supported by angle-resolved photoemission spectroscopy (ARPES) and theoretical modeling. We analyze modulations of the local density of states (LDOS) near and away from Fe vacancy defects separately and identify quasiparticle interference (QPI) signals originating from multiple regions of the Brillouin zone, including the bands at the zone corners. We also observe that QPI signals coexist with a much stronger LDOS modulation for states near the Fermi level whose period is independent of energy. Our measurements further reveal that this strong pattern appears in the STS measurements as short range stripe patterns that are locally two-fold symmetric. Since these stripe patterns coexist with four-fold symmetric QPI around Fe-vacancies, the origin of their local two-fold symmetry must be distinct from that of nematic states in orthorhombic samples. We explore several aspects related to the stripes, such as the role of S and Fe-vacancy defects, and whether they can be explained by QPI. We consider the possibility that the observed stripe patterns may represent incipient charge order correlations, similar to those observed in the cuprates.
Published: 2023

7. Influence of glacier type on bloom phenology in two Southwest Greenland fjords

Author: Stuart-Lee, Alice E., Mortensen, J., Juul-Pedersen, T., Middelburg, J.J., Soetaert, Karline, Hopwood, Mark J., Engel, Anja, Meire, Lorenz, Stuart-Lee, Alice E., Mortensen, J., Juul-Pedersen, T., Middelburg, J.J., Soetaert, Karline, Hopwood, Mark J., Engel, Anja, and Meire, Lorenz
Abstract: Highlights: • Higher representation of picophytoplankton in land-terminating glacier fjord. • Smaller phytoplankton cells associated with glacial retreat. • Intermediate baroclinic circulation influences phytoplankton distribution. • Glacial retreat likely to have major implications for summer productivity. Abstract: Along Greenland's coastline, the magnitude and timing of primary production in fjords is influenced by meltwater release from marine-terminating glaciers. How local ecosystems will adapt as these glaciers retreat onto land, forcing fundamental changes in hydrography, remains an open question. To further our understanding of this transition, we examine how marine- and land-terminating glaciers respectively influence fjord bloom phenology. Between spring and autumn 2019, we conducted along-fjord transects of hydrographic variables, biogeochemical properties and pico- and nanophytoplankton counts to illustrate the contrasting seasonal bloom dynamics in the fjords Nuup Kangerlua and Ameralik. These fjords are in the same climatic region of west Greenland but influenced by different glacial structures. Nuup Kangerlua, a predominantly marine-terminating system, was differentiated by its sustained second summer bloom and high Chl a fluorescence in summer and autumn. In Ameralik, influenced by a land-terminating glacier, we found higher abundances of pico- and nanophytoplankton, and high cyanobacteria growth in autumn. The summer bloom in Nuup Kangerlua is known to be coincident with subglacial freshwater discharge sustaining renewed nutrient supply to the fjord. We observe here that the intermediate baroclinic circulation, which creates an inflow at subsurface depths, also plays an important role in increasing nutrient availability at shallower depths and potentially explains the distribution of primary producers. Our observations suggest that the retreat of marine-terminating glaciers onto land, with consequent increases in surface water temperature and strat
Published: 2023
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8. Influence of glacier type on bloom phenology in two Southwest Greenland fjords

Author: Stuart-Lee, A. E., Mortensen, J., Juul-Pedersen, T., Middelburg, J.J., Soetaert, K., Hopwood, M. J., Engel, Anja, Meire, L., Stuart-Lee, A. E., Mortensen, J., Juul-Pedersen, T., Middelburg, J.J., Soetaert, K., Hopwood, M. J., Engel, Anja, and Meire, L.
Abstract: Highlights: • Higher representation of picophytoplankton in land-terminating glacier fjord. • Smaller phytoplankton cells associated with glacial retreat. • Intermediate baroclinic circulation influences phytoplankton distribution. • Glacial retreat likely to have major implications for summer productivity. Abstract: Along Greenland's coastline, the magnitude and timing of primary production in fjords is influenced by meltwater release from marine-terminating glaciers. How local ecosystems will adapt as these glaciers retreat onto land, forcing fundamental changes in hydrography, remains an open question. To further our understanding of this transition, we examine how marine- and land-terminating glaciers respectively influence fjord bloom phenology. Between spring and autumn 2019, we conducted along-fjord transects of hydrographic variables, biogeochemical properties and pico- and nanophytoplankton counts to illustrate the contrasting seasonal bloom dynamics in the fjords Nuup Kangerlua and Ameralik. These fjords are in the same climatic region of west Greenland but influenced by different glacial structures. Nuup Kangerlua, a predominantly marine-terminating system, was differentiated by its sustained second summer bloom and high Chl a fluorescence in summer and autumn. In Ameralik, influenced by a land-terminating glacier, we found higher abundances of pico- and nanophytoplankton, and high cyanobacteria growth in autumn. The summer bloom in Nuup Kangerlua is known to be coincident with subglacial freshwater discharge sustaining renewed nutrient supply to the fjord. We observe here that the intermediate baroclinic circulation, which creates an inflow at subsurface depths, also plays an important role in increasing nutrient availability at shallower depths and potentially explains the distribution of primary producers. Our observations suggest that the retreat of marine-terminating glaciers onto land, with consequent increases in surface water temperature and strat
Published: 2023
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9. Influence of glacier type on bloom phenology in two Southwest Greenland fjords

Author: Geochemistry, Stuart-Lee, A.E., Mortensen, J., Juul-Pedersen, T., Middelburg, J.j., Soetaert, K., Hopwood, M.j., Engel, A., Meire, L., Geochemistry, Stuart-Lee, A.E., Mortensen, J., Juul-Pedersen, T., Middelburg, J.j., Soetaert, K., Hopwood, M.j., Engel, A., and Meire, L.
Published: 2023

10. Influence of glacier type on bloom phenology in two Southwest Greenland fjords

Author: Stuart-Lee, A.E., Mortensen, J., Juul-Pedersen, T., Middelburg, J.J., Soetaert, K., Hopwood, M.J., Engel, A., Meire, L., Stuart-Lee, A.E., Mortensen, J., Juul-Pedersen, T., Middelburg, J.J., Soetaert, K., Hopwood, M.J., Engel, A., and Meire, L.
Abstract: Along Greenland's coastline, the magnitude and timing of primary production in fjords is influenced by meltwater release from marine-terminating glaciers. How local ecosystems will adapt as these glaciers retreat onto land, forcing fundamental changes in hydrography, remains an open question. To further our understanding of this transition, we examine how marine- and land-terminating glaciers respectively influence fjord bloom phenology. Between spring and autumn 2019, we conducted along-fjord transects of hydrographic variables, biogeochemical properties and pico- and nanophytoplankton counts to illustrate the contrasting seasonal bloom dynamics in the fjords Nuup Kangerlua and Ameralik. These fjords are in the same climatic region of west Greenland but influenced by different glacial structures. Nuup Kangerlua, a predominantly marine-terminating system, was differentiated by its sustained second summer bloom and high Chl a fluorescence in summer and autumn. In Ameralik, influenced by a land-terminating glacier, we found higher abundances of pico- and nanophytoplankton, and high cyanobacteria growth in autumn. The summer bloom in Nuup Kangerlua is known to be coincident with subglacial freshwater discharge sustaining renewed nutrient supply to the fjord. We observe here that the intermediate baroclinic circulation, which creates an inflow at subsurface depths, also plays an important role in increasing nutrient availability at shallower depths and potentially explains the distribution of primary producers. Our observations suggest that the retreat of marine-terminating glaciers onto land, with consequent increases in surface water temperature and stratification, and reduced light availability, may alter the magnitude, composition, and distribution of summer productivity.
Published: 2023

11. Influence of glacier type on bloom phenology in two Southwest Greenland fjords

Author: Stuart-Lee, Alice E., Mortensen, J., Juul-Pedersen, T., Middelburg, J.J., Soetaert, Karline, Hopwood, Mark J., Engel, Anja, Meire, Lorenz, Stuart-Lee, Alice E., Mortensen, J., Juul-Pedersen, T., Middelburg, J.J., Soetaert, Karline, Hopwood, Mark J., Engel, Anja, and Meire, Lorenz
Abstract: Highlights: • Higher representation of picophytoplankton in land-terminating glacier fjord. • Smaller phytoplankton cells associated with glacial retreat. • Intermediate baroclinic circulation influences phytoplankton distribution. • Glacial retreat likely to have major implications for summer productivity. Abstract: Along Greenland's coastline, the magnitude and timing of primary production in fjords is influenced by meltwater release from marine-terminating glaciers. How local ecosystems will adapt as these glaciers retreat onto land, forcing fundamental changes in hydrography, remains an open question. To further our understanding of this transition, we examine how marine- and land-terminating glaciers respectively influence fjord bloom phenology. Between spring and autumn 2019, we conducted along-fjord transects of hydrographic variables, biogeochemical properties and pico- and nanophytoplankton counts to illustrate the contrasting seasonal bloom dynamics in the fjords Nuup Kangerlua and Ameralik. These fjords are in the same climatic region of west Greenland but influenced by different glacial structures. Nuup Kangerlua, a predominantly marine-terminating system, was differentiated by its sustained second summer bloom and high Chl a fluorescence in summer and autumn. In Ameralik, influenced by a land-terminating glacier, we found higher abundances of pico- and nanophytoplankton, and high cyanobacteria growth in autumn. The summer bloom in Nuup Kangerlua is known to be coincident with subglacial freshwater discharge sustaining renewed nutrient supply to the fjord. We observe here that the intermediate baroclinic circulation, which creates an inflow at subsurface depths, also plays an important role in increasing nutrient availability at shallower depths and potentially explains the distribution of primary producers. Our observations suggest that the retreat of marine-terminating glaciers onto land, with consequent increases in surface water temperature and strat
Published: 2023
Full Text: View/download PDF

12. Influence of glacier type on bloom phenology in two Southwest Greenland fjords

Author: Geochemistry, Stuart-Lee, A.E., Mortensen, J., Juul-Pedersen, T., Middelburg, J.j., Soetaert, K., Hopwood, M.j., Engel, A., Meire, L., Geochemistry, Stuart-Lee, A.E., Mortensen, J., Juul-Pedersen, T., Middelburg, J.j., Soetaert, K., Hopwood, M.j., Engel, A., and Meire, L.
Published: 2023

13. Influence of glacier type on bloom phenology in two Southwest Greenland fjords

Author: Stuart-Lee, Alice E., Mortensen, J., Juul-Pedersen, T., Middelburg, J.J., Soetaert, Karline, Hopwood, Mark J., Engel, Anja, Meire, Lorenz, Stuart-Lee, Alice E., Mortensen, J., Juul-Pedersen, T., Middelburg, J.J., Soetaert, Karline, Hopwood, Mark J., Engel, Anja, and Meire, Lorenz
Abstract: Highlights: • Higher representation of picophytoplankton in land-terminating glacier fjord. • Smaller phytoplankton cells associated with glacial retreat. • Intermediate baroclinic circulation influences phytoplankton distribution. • Glacial retreat likely to have major implications for summer productivity. Abstract: Along Greenland's coastline, the magnitude and timing of primary production in fjords is influenced by meltwater release from marine-terminating glaciers. How local ecosystems will adapt as these glaciers retreat onto land, forcing fundamental changes in hydrography, remains an open question. To further our understanding of this transition, we examine how marine- and land-terminating glaciers respectively influence fjord bloom phenology. Between spring and autumn 2019, we conducted along-fjord transects of hydrographic variables, biogeochemical properties and pico- and nanophytoplankton counts to illustrate the contrasting seasonal bloom dynamics in the fjords Nuup Kangerlua and Ameralik. These fjords are in the same climatic region of west Greenland but influenced by different glacial structures. Nuup Kangerlua, a predominantly marine-terminating system, was differentiated by its sustained second summer bloom and high Chl a fluorescence in summer and autumn. In Ameralik, influenced by a land-terminating glacier, we found higher abundances of pico- and nanophytoplankton, and high cyanobacteria growth in autumn. The summer bloom in Nuup Kangerlua is known to be coincident with subglacial freshwater discharge sustaining renewed nutrient supply to the fjord. We observe here that the intermediate baroclinic circulation, which creates an inflow at subsurface depths, also plays an important role in increasing nutrient availability at shallower depths and potentially explains the distribution of primary producers. Our observations suggest that the retreat of marine-terminating glaciers onto land, with consequent increases in surface water temperature and strat
Published: 2023
Full Text: View/download PDF

14. Multidecadal water mass dynamics on the West Greenland shelf

Author: Mortensen, J., Rysgaard, S., Winding, M.H.S., Juul-Pedersen, T., Arendt, K.E., Lund, H., Stuart-Lee, A.E., Meire, L., Mortensen, J., Rysgaard, S., Winding, M.H.S., Juul-Pedersen, T., Arendt, K.E., Lund, H., Stuart-Lee, A.E., and Meire, L.
Abstract: The waters on the West Greenland continental shelf and slope play an important role in the global climate system with their link to the subpolar North Atlantic Ocean circulation system and the Greenland Ice Sheet. Lately, low temperature waters on the West Greenland shelf have been observed as far south as ∼64°N and associated with a cold and relatively saline water mass originating north of Davis Strait in Baffin Bay referred to as Baffin Bay Polar Water (BBPW). Here we use long, seasonal hydrographic time series from West Greenland at ∼64°N to study how frequently BBPW is reaching this far south. The analysis covers the period 1950–2018 with a data gap between 1988 and 2005. BBPW was observed frequently and was responsible for the temperature changes observed in the late 1960s–1980s and more intermittently post-2008. Some of the large temperature changes we observe in the time series have previously been ascribed to “Great Salinity Anomalies” (GSAs) propagating around the subpolar North Atlantic Ocean circulation system. The prevailing view of the propagation of GSAs has been ascribed to advection of anomalies along the large-scale circulation system. Our study shows that BBPW may play an important role in the interpretation of GSAs and melt of the Greenland Ice Sheet. Large temporal temperature changes at ∼64°N are associated with arrival of BBPW from the north and not advection of anomalies with the large-scale current system from the south. This advocates for a shift in water masses caused by changes in the position and/or strength of oceanic currents.
Published: 2022

15. Detection of Klebsiella pneumoniae human gut carriage: a comparison of culture, qPCR, and whole metagenomic sequencing methods

Author: Lindstedt, K, Buczek, D, Pedersen, T, Hjerde, E, Raffelsberger, N, Suzuki, Y, Brisse, S, Holt, K, Samuelsen, O, Sundsfjord, A, Lindstedt, K, Buczek, D, Pedersen, T, Hjerde, E, Raffelsberger, N, Suzuki, Y, Brisse, S, Holt, K, Samuelsen, O, and Sundsfjord, A
Abstract: Klebsiella pneumoniae is an important opportunistic healthcare-associated pathogen and major contributor to the global spread of antimicrobial resistance. Gastrointestinal colonization with K. pneumoniae is a major predisposing risk factor for infection and forms an important hub for the dispersal of resistance. Current culture-based detection methods are time consuming, give limited intra-sample abundance and strain diversity information, and have uncertain sensitivity. Here we investigated the presence and abundance of K. pneumoniae at the species and strain level within fecal samples from 103 community-based adults by qPCR and whole metagenomic sequencing (WMS) compared to culture-based detection. qPCR demonstrated the highest sensitivity, detecting K. pneumoniae in 61.2% and 75.8% of direct-fecal and culture-enriched sweep samples, respectively, including 52/52 culture-positive samples. WMS displayed lower sensitivity, detecting K. pneumoniae in 71.2% of culture-positive fecal samples at a 0.01% abundance cutoff, and was inclined to false positives in proportion to the relative abundance of other Enterobacterales present. qPCR accurately quantified K. pneumoniae to 16 genome copies/reaction while WMS could estimate relative abundance to at least 0.01%. Quantification by both methods correlated strongly with each other (Spearman's rho = 0.91). WMS also supported accurate intra-sample K. pneumoniae sequence type (ST)-level diversity detection from fecal microbiomes to 0.1% relative abundance, agreeing with the culture-based detected ST in 16/19 samples. Our results show that qPCR and WMS are sensitive and reliable tools for detection, quantification, and strain analysis of K. pneumoniae from fecal samples with potential to support infection control and enhance insights in K. pneumoniae gastrointestinal ecology.
Published: 2022

16. Glacial meltwater determines the balance between autotrophic and heterotrophic processes in a Greenland fjord

Author: Sejr, M.K., Bruhn, A., Dalsgaard, T., Juul-Pedersen, T., Stedmon, C.A., Blicher, M., Meire, L., Mankoff, K.D., Thyrring, J., Sejr, M.K., Bruhn, A., Dalsgaard, T., Juul-Pedersen, T., Stedmon, C.A., Blicher, M., Meire, L., Mankoff, K.D., and Thyrring, J.
Abstract: Global warming accelerates melting of glaciers and increases the supply of meltwater and associated inorganic particles, nutrients, and organic matter to adjacent coastal seas, but the ecosystem impact is poorly resolved and quantified. When meltwater is delivered by glacial rivers, the potential impact could be a reduction in light and nutrient availability for primary producers while supplying allochthonous carbon for heterotrophic processes, thereby tipping the net community metabolism toward heterotrophy. To test this hypothesis, we determined physical and biogeochemical parameters along a 110-km fjord transect in NE Greenland fjord, impacted by glacial meltwater from the Greenland Ice Sheet. The meltwater is delivered from glacier-fed river outlets in the inner parts of the fjord, creating a gradient in salinity and turbidity. The planktonic primary production was low, 20–45 mg C m−2 d−1, in the more turbid innerhalf of the fjord, increasing 10-fold to around 350 mg C m−2 d −1 in the shelf waters outside the fjord. Plankton community metabolism was measured at three stations, which displayed a transition from net heterotrophy in the inner fjord to net autotrophy in the coastal shelf waters. Respiration was significantly correlated to turbidity, with a 10-fold increase in the inner turbid part of the fjord. We estimated the changes in meltwater input and sea ice coverage in the area for the last 60 y. The long-term trend and the observed effects demonstrated the importance of freshwater runoff as a key driver of coastal ecosystem change in the Arctic with potential negative consequences for coastal productivity.
Published: 2022

17. Multidecadal water mass dynamics on the West Greenland shelf

Author: Mortensen, J., Rysgaard, S., Winding, M.H.S., Juul-Pedersen, T., Arendt, K.E., Lund, H., Stuart-Lee, A.E., Meire, L., Mortensen, J., Rysgaard, S., Winding, M.H.S., Juul-Pedersen, T., Arendt, K.E., Lund, H., Stuart-Lee, A.E., and Meire, L.
Abstract: The waters on the West Greenland continental shelf and slope play an important role in the global climate system with their link to the subpolar North Atlantic Ocean circulation system and the Greenland Ice Sheet. Lately, low temperature waters on the West Greenland shelf have been observed as far south as ∼64°N and associated with a cold and relatively saline water mass originating north of Davis Strait in Baffin Bay referred to as Baffin Bay Polar Water (BBPW). Here we use long, seasonal hydrographic time series from West Greenland at ∼64°N to study how frequently BBPW is reaching this far south. The analysis covers the period 1950–2018 with a data gap between 1988 and 2005. BBPW was observed frequently and was responsible for the temperature changes observed in the late 1960s–1980s and more intermittently post-2008. Some of the large temperature changes we observe in the time series have previously been ascribed to “Great Salinity Anomalies” (GSAs) propagating around the subpolar North Atlantic Ocean circulation system. The prevailing view of the propagation of GSAs has been ascribed to advection of anomalies along the large-scale circulation system. Our study shows that BBPW may play an important role in the interpretation of GSAs and melt of the Greenland Ice Sheet. Large temporal temperature changes at ∼64°N are associated with arrival of BBPW from the north and not advection of anomalies with the large-scale current system from the south. This advocates for a shift in water masses caused by changes in the position and/or strength of oceanic currents.
Published: 2022

18. Evaluation of the effect of sodium–glucose co-transporter 2 inhibition with empagliflozin on morbidity and mortality of patients with chronic heart failure and a reduced ejection fraction: rationale for and design of the EMPEROR-Reduced trial

Author: Packer, M, Butler, J, Filippatos, G, Jamal, W, Salsali, A, Schnee, J, Kimura, K, Zeller, C, George, J, Brueckmann, M, Anker, S, Zannad, F, Perrone, S, Nicholls, S, Janssens, S, Bocchi, E, Giannetti, N, Verma, S, Jian, Z, Spinar, J, Seronde, M, Bohm, M, Merkely, B, Chopra, V, Senni, M, Taddei, S, Tsutsui, H, Choi, D, Chuquiure, E, La Rocca, H, Ponikowski, P, Juanatey, J, Squire, I, Januzzi, J, Pina, I, Pocock, S, Carson, P, Doehner, W, Miller, A, Haas, M, Pehrson, S, Komajda, M, Anand, I, Teerlink, J, Rabinstein, A, Steiner, T, Kamel, H, Tsivgoulis, G, Lewis, J, Freston, J, Kaplowitz, N, Mann, J, Petrie, M, Bernstein, R, Cheung, A, Green, J, Kaul, S, Ping, C, Lip, G, Marx, N, Mccullough, P, Mehta, C, Rosenstock, J, Sattar, N, Scirica, B, Wanner, C, Welty, F, Parhofer, K, Clayton, T, Pedersen, T, Lees, K, Konstam, M, Greenberg, B, Palmer, M, Packer M., Butler J., Filippatos G. S., Jamal W., Salsali A., Schnee J., Kimura K., Zeller C., George J., Brueckmann M., Anker S. D., Zannad F., Perrone S., Nicholls S., Janssens S., Bocchi E., Giannetti N., Verma S., Jian Z., Spinar J., Seronde M. -F., Bohm M., Merkely B., Chopra V., Senni M., Taddei S., Tsutsui H., Choi D. -J., Chuquiure E., La Rocca H. P. B., Ponikowski P., Juanatey J. R. G., Squire I., Januzzi J., Pina I., Pocock S. J., Carson P., Doehner W., Miller A., Haas M., Pehrson S., Komajda M., Anand I., Teerlink J., Rabinstein A., Steiner T., Kamel H., Tsivgoulis G., Lewis J., Freston J., Kaplowitz N., Mann J., Petrie M., Bernstein R., Cheung A., Green J., Kaul S., Ping C. L. S., Lip G., Marx N., McCullough P., Mehta C., Rosenstock J., Sattar N., Scirica B., Wanner C., Welty F. K., Parhofer K. G., Clayton T., Pedersen T. R., Lees K. R., Konstam M. A., Greenberg B., Palmer M., Packer, M, Butler, J, Filippatos, G, Jamal, W, Salsali, A, Schnee, J, Kimura, K, Zeller, C, George, J, Brueckmann, M, Anker, S, Zannad, F, Perrone, S, Nicholls, S, Janssens, S, Bocchi, E, Giannetti, N, Verma, S, Jian, Z, Spinar, J, Seronde, M, Bohm, M, Merkely, B, Chopra, V, Senni, M, Taddei, S, Tsutsui, H, Choi, D, Chuquiure, E, La Rocca, H, Ponikowski, P, Juanatey, J, Squire, I, Januzzi, J, Pina, I, Pocock, S, Carson, P, Doehner, W, Miller, A, Haas, M, Pehrson, S, Komajda, M, Anand, I, Teerlink, J, Rabinstein, A, Steiner, T, Kamel, H, Tsivgoulis, G, Lewis, J, Freston, J, Kaplowitz, N, Mann, J, Petrie, M, Bernstein, R, Cheung, A, Green, J, Kaul, S, Ping, C, Lip, G, Marx, N, Mccullough, P, Mehta, C, Rosenstock, J, Sattar, N, Scirica, B, Wanner, C, Welty, F, Parhofer, K, Clayton, T, Pedersen, T, Lees, K, Konstam, M, Greenberg, B, Palmer, M, Packer M., Butler J., Filippatos G. S., Jamal W., Salsali A., Schnee J., Kimura K., Zeller C., George J., Brueckmann M., Anker S. D., Zannad F., Perrone S., Nicholls S., Janssens S., Bocchi E., Giannetti N., Verma S., Jian Z., Spinar J., Seronde M. -F., Bohm M., Merkely B., Chopra V., Senni M., Taddei S., Tsutsui H., Choi D. -J., Chuquiure E., La Rocca H. P. B., Ponikowski P., Juanatey J. R. G., Squire I., Januzzi J., Pina I., Pocock S. J., Carson P., Doehner W., Miller A., Haas M., Pehrson S., Komajda M., Anand I., Teerlink J., Rabinstein A., Steiner T., Kamel H., Tsivgoulis G., Lewis J., Freston J., Kaplowitz N., Mann J., Petrie M., Bernstein R., Cheung A., Green J., Kaul S., Ping C. L. S., Lip G., Marx N., McCullough P., Mehta C., Rosenstock J., Sattar N., Scirica B., Wanner C., Welty F. K., Parhofer K. G., Clayton T., Pedersen T. R., Lees K. R., Konstam M. A., Greenberg B., and Palmer M.
Abstract: Drugs that inhibit the sodium–glucose co-transporter 2 (SGLT2) have been shown to reduce the risk of hospitalizations for heart failure in patients with type 2 diabetes. In populations that largely did not have heart failure at the time of enrolment, empagliflozin, canagliflozin and dapagliflozin decreased the risk of serious new-onset heart failure events by ≈30%. In addition, in the EMPA-REG OUTCOME trial, empagliflozin reduced the risk of both pump failure and sudden deaths, the two most common modes of death among patients with heart failure. In none of the three trials could the benefits of SGLT2 inhibitors on heart failure be explained by the actions of these drugs as diuretics or anti-hyperglycaemic agents. These observations raise the possibility that SGLT2 inhibitors could reduce morbidity and mortality in patients with established heart failure, including those without diabetes. The EMPEROR-Reduced trial is enrolling ≈3600 patients with heart failure and a reduced left ventricular ejection fraction (≤ 40%), half of whom are expected not to have diabetes. Patients are being randomized to placebo or empagliflozin 10 mg daily, which is added to all appropriate treatment with inhibitors of the renin–angiotensin system and neprilysin, beta-blockers and mineralocorticoid receptor antagonists. The primary endpoint is the time-to-first event analysis of the combined risk of cardiovascular death and hospitalization for heart failure, but the trial will also evaluate the effects of empagliflozin on renal function, cardiovascular death, all-cause mortality, and recurrent hospitalization events. By adjusting eligibility based on natriuretic peptide levels to the baseline ejection fraction, the trial will preferentially enrol high-risk patients. A large proportion of the participants is expected to have an ejection fraction < 30%, and the estimated annual event rate is expected to be at least 15%. The EMPEROR-Reduced trial is well-positioned to determine if the addi
Published: 2019

19. Evaluation of the effects of sodium–glucose co-transporter 2 inhibition with empagliflozin on morbidity and mortality in patients with chronic heart failure and a preserved ejection fraction: rationale for and design of the EMPEROR-Preserved Trial

Author: Anker, S, Butler, J, Filippatos, G, Jamal, W, Salsali, A, Schnee, J, Kimura, K, Zeller, C, George, J, Brueckmann, M, Zannad, F, Packer, M, Perrone, S, Nicholls, S, Janssens, S, Bocchi, E, Giannetti, N, Verma, S, Jian, Z, Gomez Mesa, J, Spinar, J, Bohm, M, Merkely, B, Chopra, V, Senni, M, Taddi, S, Tsutsui, H, Chuquiure, E, La Rocca, H, Ponikowski, P, Vinereanu, D, Sim, D, Choi, D, Juanatey, J, Squire, I, Januzzi, J, Pina, I, Pocock, S, Carson, P, Doehner, W, Miller, A, Haas, M, Pehrson, S, Komajda, M, Anand, I, Teerlink, J, Rabinstein, A, Steiner, T, Kamel, H, Tsivgoulis, G, Lewis, J, Freston, J, Kaplowitz, N, Mann, J, Petrie, M, Bernstein, R, Cheung, A, Green, J, Kaul, S, Ping, C, Lip, G, Marx, N, Mccullough, P, Mehta, C, Rosenstock, J, Sattar, N, Scirica, B, Wanner, C, Welty, F, Parhofer, K, Clayton, T, Pedersen, T, Lees, K, Konstam, M, Greenberg, B, Palmer, M, Anker S. D., Butler J., Filippatos G. S., Jamal W., Salsali A., Schnee J., Kimura K., Zeller C., George J., Brueckmann M., Zannad F., Packer M., Perrone S., Nicholls S., Janssens S., Bocchi E., Giannetti N., Verma S., Jian Z., Gomez Mesa J. E., Spinar J., Bohm M., Merkely B., Chopra V., Senni M., Taddi S., Tsutsui H., Chuquiure E., La Rocca H. P. B., Ponikowski P., Vinereanu D., Sim D., Choi D. -J., Juanatey J. R. G., Squire I., Januzzi J., Pina I., Pocock S. J., Carson P., Doehner W., Miller A., Haas M., Pehrson S., Komajda M., Anand I., Teerlink J., Rabinstein A., Steiner T., Kamel H., Tsivgoulis G., Lewis J., Freston J., Kaplowitz N., Mann J., Petrie M., Bernstein R., Cheung A., Green J., Kaul S., Ping C. L. S., Lip G., Marx N., McCullough P., Mehta C., Rosenstock J., Sattar N., Scirica B., Wanner C., Welty F. K., Parhofer K. G., Clayton T., Pedersen T. R., Lees K. R., Konstam M. A., Greenberg B., Palmer M., Anker, S, Butler, J, Filippatos, G, Jamal, W, Salsali, A, Schnee, J, Kimura, K, Zeller, C, George, J, Brueckmann, M, Zannad, F, Packer, M, Perrone, S, Nicholls, S, Janssens, S, Bocchi, E, Giannetti, N, Verma, S, Jian, Z, Gomez Mesa, J, Spinar, J, Bohm, M, Merkely, B, Chopra, V, Senni, M, Taddi, S, Tsutsui, H, Chuquiure, E, La Rocca, H, Ponikowski, P, Vinereanu, D, Sim, D, Choi, D, Juanatey, J, Squire, I, Januzzi, J, Pina, I, Pocock, S, Carson, P, Doehner, W, Miller, A, Haas, M, Pehrson, S, Komajda, M, Anand, I, Teerlink, J, Rabinstein, A, Steiner, T, Kamel, H, Tsivgoulis, G, Lewis, J, Freston, J, Kaplowitz, N, Mann, J, Petrie, M, Bernstein, R, Cheung, A, Green, J, Kaul, S, Ping, C, Lip, G, Marx, N, Mccullough, P, Mehta, C, Rosenstock, J, Sattar, N, Scirica, B, Wanner, C, Welty, F, Parhofer, K, Clayton, T, Pedersen, T, Lees, K, Konstam, M, Greenberg, B, Palmer, M, Anker S. D., Butler J., Filippatos G. S., Jamal W., Salsali A., Schnee J., Kimura K., Zeller C., George J., Brueckmann M., Zannad F., Packer M., Perrone S., Nicholls S., Janssens S., Bocchi E., Giannetti N., Verma S., Jian Z., Gomez Mesa J. E., Spinar J., Bohm M., Merkely B., Chopra V., Senni M., Taddi S., Tsutsui H., Chuquiure E., La Rocca H. P. B., Ponikowski P., Vinereanu D., Sim D., Choi D. -J., Juanatey J. R. G., Squire I., Januzzi J., Pina I., Pocock S. J., Carson P., Doehner W., Miller A., Haas M., Pehrson S., Komajda M., Anand I., Teerlink J., Rabinstein A., Steiner T., Kamel H., Tsivgoulis G., Lewis J., Freston J., Kaplowitz N., Mann J., Petrie M., Bernstein R., Cheung A., Green J., Kaul S., Ping C. L. S., Lip G., Marx N., McCullough P., Mehta C., Rosenstock J., Sattar N., Scirica B., Wanner C., Welty F. K., Parhofer K. G., Clayton T., Pedersen T. R., Lees K. R., Konstam M. A., Greenberg B., and Palmer M.
Abstract: Background: The principal biological processes that characterize heart failure with a preserved ejection fraction (HFpEF) are systemic inflammation, epicardial adipose tissue accumulation, coronary microcirculatory rarefaction, myocardial fibrosis and vascular stiffness; the resulting impairment of left ventricular and aortic distensibility (especially when accompanied by impaired glomerular function and sodium retention) causes increases in cardiac filling pressures and exertional dyspnoea despite the relative preservation of left ventricular ejection fraction. Independently of their actions on blood glucose, sodium–glucose co-transporter 2 (SGLT2) inhibitors exert a broad range of biological effects (including actions to inhibit cardiac inflammation and fibrosis, antagonize sodium retention and improve glomerular function) that can ameliorate the pathophysiological derangements in HFpEF. Such SGLT2 inhibitors exert favourable effects in experimental models of HFpEF and have been found in large-scale trials to reduce the risk for serious heart failure events in patients with type 2 diabetes, many of whom were retrospectively identified as having HFpEF. Study design: The EMPEROR-Preserved Trial is enrolling ≈5750 patients with HFpEF (ejection fraction >40%), with and without type 2 diabetes, who are randomized to receive placebo or empagliflozin 10 mg/day, which is added to all appropriate treatments for HFpEF and co-morbidities. Study aims: The primary endpoint is the time-to-first-event analysis of the combined risk for cardiovascular death or hospitalization for heart failure. The trial will also evaluate the effects of empagliflozin on renal function, cardiovascular death,. all-cause mortality and recurrent hospitalization events, and will assess a wide range of biomarkers that reflect important pathophysiological mechanisms that may drive the evolution of HFpEF. The EMPEROR-Preserved Trial is well positioned to determine if empagliflozin can have a meaningfu
Published: 2019

20. Performance of Wendelstein 7-X stellarator plasmas during the first divertor operation phase

Author: Massachusetts Institute of Technology. Department of Physics, Wolf, R. C., Alonso, A., Äkäslompolo, S., Baldzuhn, J., Beurskens, M., Beidler, C. D., Biedermann, C., Bosch, H.-S., Bozhenkov, S., Brakel, R., Braune, H., Brezinsek, S., Brunner, K.-J., Damm, H., Dinklage, A., Drewelow, P., Effenberg, F., Feng, Y., Ford, O., Fuchert, G., Gao, Y., Geiger, J., Grulke, O., Harder, N., Hartmann, D., Helander, P., Heinemann, B., Hirsch, M., Höfel, U., Hopf, C., Ida, K., Isobe, M., Jakubowski, M. W., Kazakov, Y. O., Killer, C., Klinger, T., Knauer, J., König, R., Krychowiak, M., Langenberg, A., Laqua, H. P., Lazerson, S., McNeely, P., Marsen, S., Marushchenko, N., Nocentini, R., Ogawa, K., Orozco, G., Osakabe, M., Otte, M., Pablant, N., Pasch, E., Pavone, A., Porkolab, Miklos, Puig Sitjes, A., Rahbarnia, K., Riedl, R., Rust, N., Scott, E., Schilling, J., Schroeder, R., Stange, T., von Stechow, A., Strumberger, E., Sunn Pedersen, T., Svensson, J., Thomson, H., Turkin, Y., Vano, L., Wauters, T., Wurden, G., Yoshinuma, M., Zanini, M., Zhang, D., Massachusetts Institute of Technology. Department of Physics, Wolf, R. C., Alonso, A., Äkäslompolo, S., Baldzuhn, J., Beurskens, M., Beidler, C. D., Biedermann, C., Bosch, H.-S., Bozhenkov, S., Brakel, R., Braune, H., Brezinsek, S., Brunner, K.-J., Damm, H., Dinklage, A., Drewelow, P., Effenberg, F., Feng, Y., Ford, O., Fuchert, G., Gao, Y., Geiger, J., Grulke, O., Harder, N., Hartmann, D., Helander, P., Heinemann, B., Hirsch, M., Höfel, U., Hopf, C., Ida, K., Isobe, M., Jakubowski, M. W., Kazakov, Y. O., Killer, C., Klinger, T., Knauer, J., König, R., Krychowiak, M., Langenberg, A., Laqua, H. P., Lazerson, S., McNeely, P., Marsen, S., Marushchenko, N., Nocentini, R., Ogawa, K., Orozco, G., Osakabe, M., Otte, M., Pablant, N., Pasch, E., Pavone, A., Porkolab, Miklos, Puig Sitjes, A., Rahbarnia, K., Riedl, R., Rust, N., Scott, E., Schilling, J., Schroeder, R., Stange, T., von Stechow, A., Strumberger, E., Sunn Pedersen, T., Svensson, J., Thomson, H., Turkin, Y., Vano, L., Wauters, T., Wurden, G., Yoshinuma, M., Zanini, M., and Zhang, D.
Published: 2021

21. Trace element (Fe, Co, Ni and Cu) dynamics across the salinity gradient in Arctic and Antarctic glacier fjords

Author: Krause, J., Hopwood, M.J., Höfer, J., Krisch, S., Achterberg, E.P., Alarcón, E., Carroll, D., González, H.E., Juul-Pedersen, T., Liu, T., Lodeiro, P., Meire, L., Rosing, M.T., Krause, J., Hopwood, M.J., Höfer, J., Krisch, S., Achterberg, E.P., Alarcón, E., Carroll, D., González, H.E., Juul-Pedersen, T., Liu, T., Lodeiro, P., Meire, L., and Rosing, M.T.
Abstract: Around the Greenlandic and Antarctic coastlines, sediment plumes associated with glaciers are significant sources of lithogenic material to the ocean. These plumes contain elevated concentrations of a range of trace metals, especially in particle bound phases, but it is not clear how these particles affect dissolved (<0.2 µm) metal distributions in the ocean. Here we show, using transects in 8 glacier fjords, trends in the distribution of dissolved iron, cobalt, nickel and copper (dFe, dCo, dNi, dCu). Following rapid dFe loss close to glacier outflows, dFe concentrations in particular showed strong similarities between different fjords. Similar dFe concentrations were also observed between seasons/years when Nuup Kangerlua (SW Greenland) was revisited in spring, mid- and late-summer. Dissolved Cu, dCo and dNi concentrations were more variable and showed different gradients with salinity depending on the fjord, season and year. The lack of consistent trends for dCu and dNi largely reflects less pronounced differences contrasting the concentration of inflowing shelf waters with fresher glacially-modified waters. Particles also made only small contributions to total dissolvable Cu (dCu constituted 83 ± 28% of total dissolvable Cu) and Ni (dNi constituted 86 ± 28% of total dissolvable Ni) within glacier plumes. For comparison, dFe was a lower fraction of total dissolvable Fe; 3.5 ± 4.8%. High concentrations of total dissolvable Fe in some inner-fjord environments, up to 77 µM in Ameralik (SW Greenland), may drive enhanced removal of scavenged type elements, such as Co. Further variability may have been driven by local bedrock mineralogy, which could explain high concentrations of dNi (25–29 nM) and dCo (6–7 nM) in one coastal region of west Greenland (Kangaatsiaq). Our results suggest that dissolved trace element distributions in glacier fjords are influenced by a range of factors including: freshwater concentrations, local geology, drawdown by sca
Published: 2021

22. Trace element (Fe, Co, Ni and Cu) dynamics across the salinity gradient in Arctic and Antarctic glacier fjords

Author: Krause, J., Hopwood, M.J., Höfer, J., Krisch, S., Achterberg, E.P., Alarcón, E., Carroll, D., González, H.E., Juul-Pedersen, T., Liu, T., Lodeiro, P., Meire, L., Rosing, M.T., Krause, J., Hopwood, M.J., Höfer, J., Krisch, S., Achterberg, E.P., Alarcón, E., Carroll, D., González, H.E., Juul-Pedersen, T., Liu, T., Lodeiro, P., Meire, L., and Rosing, M.T.
Abstract: Around the Greenlandic and Antarctic coastlines, sediment plumes associated with glaciers are significant sources of lithogenic material to the ocean. These plumes contain elevated concentrations of a range of trace metals, especially in particle bound phases, but it is not clear how these particles affect dissolved (<0.2 µm) metal distributions in the ocean. Here we show, using transects in 8 glacier fjords, trends in the distribution of dissolved iron, cobalt, nickel and copper (dFe, dCo, dNi, dCu). Following rapid dFe loss close to glacier outflows, dFe concentrations in particular showed strong similarities between different fjords. Similar dFe concentrations were also observed between seasons/years when Nuup Kangerlua (SW Greenland) was revisited in spring, mid- and late-summer. Dissolved Cu, dCo and dNi concentrations were more variable and showed different gradients with salinity depending on the fjord, season and year. The lack of consistent trends for dCu and dNi largely reflects less pronounced differences contrasting the concentration of inflowing shelf waters with fresher glacially-modified waters. Particles also made only small contributions to total dissolvable Cu (dCu constituted 83 ± 28% of total dissolvable Cu) and Ni (dNi constituted 86 ± 28% of total dissolvable Ni) within glacier plumes. For comparison, dFe was a lower fraction of total dissolvable Fe; 3.5 ± 4.8%. High concentrations of total dissolvable Fe in some inner-fjord environments, up to 77 µM in Ameralik (SW Greenland), may drive enhanced removal of scavenged type elements, such as Co. Further variability may have been driven by local bedrock mineralogy, which could explain high concentrations of dNi (25–29 nM) and dCo (6–7 nM) in one coastal region of west Greenland (Kangaatsiaq). Our results suggest that dissolved trace element distributions in glacier fjords are influenced by a range of factors including: freshwater concentrations, local geology, drawdown by sca
Published: 2021

23. Fungal quinones: diversity, producers, and applications of quinones from Aspergillus, Penicillium, Talaromyces, Fusarium, and Arthrinium

Author: Christiansen, J. V., Isbrandt, T., Petersen, C., Sondergaard, T. E., Nielsen, M. R., Pedersen, T. B., Sørensen, J. L., Larsen, T. O., Frisvad, J. C., Christiansen, J. V., Isbrandt, T., Petersen, C., Sondergaard, T. E., Nielsen, M. R., Pedersen, T. B., Sørensen, J. L., Larsen, T. O., and Frisvad, J. C.
Abstract: Quinones represent an important group of highly structurally diverse, mainly polyketide-derived secondary metabolites widely distributed among filamentous fungi. Many quinones have been reported to have important biological functions such as inhibition of bacteria or repression of the immune response in insects. Other quinones, such as ubiquinones are known to be essential molecules in cellular respiration, and many quinones are known to protect their producing organisms from exposure to sunlight. Most recently, quinones have also attracted a lot of industrial interest since their electron-donating and -accepting properties make them good candidates as electrolytes in redox flow batteries, like their often highly conjugated double bond systems make them attractive as pigments. On an industrial level, quinones are mainly synthesized from raw components in coal tar. However, the possibility of producing quinones by fungal cultivation has great prospects since fungi can often be grown in industrially scaled bioreactors, producing valuable metabolites on cheap substrates. In order to give a better overview of the secondary metabolite quinones produced by and shared between various fungi, mainly belonging to the genera Aspergillus, Penicillium, Talaromyces, Fusarium, and Arthrinium, this review categorizes quinones into families such as emodins, fumigatins, sorbicillinoids, yanuthones, and xanthomegnins, depending on structural similarities and information about the biosynthetic pathway from which they are derived, whenever applicable. The production of these quinone families is compared between the different genera, based on recently revised taxonomy.
Published: 2021

24. Review article: How does glacier discharge affect marine biogeochemistry and primary production in the Arctic?

Author: Hopwood, M.J., Carroll, D., Dunse, T., Hodson, A., Holding, J.M., Iriarte, J.L., Ribeiro, S., Achterberg, E.P., Cantoni, C., Carlson, D.F., Chierici, M., Clarke, J.S., Cozzi, S., Fransson, A., Juul-Pedersen, T., Winding, M.H.S., Meire, L., Hopwood, M.J., Carroll, D., Dunse, T., Hodson, A., Holding, J.M., Iriarte, J.L., Ribeiro, S., Achterberg, E.P., Cantoni, C., Carlson, D.F., Chierici, M., Clarke, J.S., Cozzi, S., Fransson, A., Juul-Pedersen, T., Winding, M.H.S., and Meire, L.
Abstract: Freshwater discharge from glaciers is increasing across the Arctic in response to anthropogenic climate change, which raises questions about the potential downstream effects in the marine environment. Whilst a combination of long-term monitoring programmes and intensive Arctic field campaigns have improved our knowledge of glacier–ocean interactions in recent years, especially with respect to fjord/ocean circulation, there are extensive knowledge gaps concerning how glaciers affect marine biogeochemistry and productivity. Following two cross-cutting disciplinary International Arctic Science Committee (IASC) workshops addressing the importance of glaciers for the marine ecosystem, here we review the state of the art concerning how freshwater discharge affects the marine environment with a specific focus on marine biogeochemistry and biological productivity. Using a series of Arctic case studies (Nuup Kangerlua/Godthåbsfjord, Kongsfjorden, Kangerluarsuup Sermia/Bowdoin Fjord, Young Sound and Sermilik Fjord), the interconnected effects of freshwater discharge on fjord–shelf exchange, nutrient availability, the carbonate system, the carbon cycle and the microbial food web are investigated. Key findings are that whether the effect of glacier discharge on marine primary production is positive or negative is highly dependent on a combination of factors. These include glacier type (marine- or land-terminating), fjord–glacier geometry and the limiting resource(s) for phytoplankton growth in a specific spatio-temporal region (light, macronutrients or micronutrients). Arctic glacier fjords therefore often exhibit distinct discharge–productivity relationships, and multiple case-studies must be considered in order to understand the net effects of glacier discharge on Arctic marine ecosystems.
Published: 2020

25. An updated view on water masses on the pan‐west Greenland continental shelf and their link to proglacial fjords

Author: Rysgaard, S., Boone, W., Carlson, D., Sejr, M.K., Bendtsen, J., Juul-Pedersen, T., Lund, H., Meire, L., Mortensen, J., Rysgaard, S., Boone, W., Carlson, D., Sejr, M.K., Bendtsen, J., Juul-Pedersen, T., Lund, H., Meire, L., and Mortensen, J.
Abstract: The accelerated melt of the Greenland Ice Sheet has been linked to a sudden increase in the presence of warm subsurface coastal water in west Greenland. Yet pathways of warm coastal water along the entire west Greenland coast have remained largely unstudied. Here we present the first, near‐synoptic hydrographic observations at both the continental slope and fjord entrances of the west Greenland coastal system from Cape Farewell (59°N) to Melville Bay (75°N) in summer 2016. We observed a distinct north‐south division in the water mass distribution in west Greenland, approximately partitioned by the northern part of Davis Strait, and a division between the continental slope and fjord entrances. Waters from the regional southern freshwater source with origin in the East Greenland Current that rounds Cape Farewell are not observed to enter Baffin Bay. The regional heat source transported by the West Greenland Current is blocked by Southwest Greenland Coastal Water in the south but the deep connections in the north allow warm deep Subpolar Mode Water to enter fjords. Furthermore, we observed cold and relative saline Baffin Bay Polar Water over the inner part of the banks, periodically reaching as far south as 64°N, suggesting the presence of an undescribed southward current at the Southwest Greenland continental shelf.
Published: 2020

26. An updated view on water masses on the pan‐west Greenland continental shelf and their link to proglacial fjords

Author: Rysgaard, S., Boone, W., Carlson, D., Sejr, M.K., Bendtsen, J., Juul-Pedersen, T., Lund, H., Meire, L., Mortensen, J., Rysgaard, S., Boone, W., Carlson, D., Sejr, M.K., Bendtsen, J., Juul-Pedersen, T., Lund, H., Meire, L., and Mortensen, J.
Abstract: The accelerated melt of the Greenland Ice Sheet has been linked to a sudden increase in the presence of warm subsurface coastal water in west Greenland. Yet pathways of warm coastal water along the entire west Greenland coast have remained largely unstudied. Here we present the first, near‐synoptic hydrographic observations at both the continental slope and fjord entrances of the west Greenland coastal system from Cape Farewell (59°N) to Melville Bay (75°N) in summer 2016. We observed a distinct north‐south division in the water mass distribution in west Greenland, approximately partitioned by the northern part of Davis Strait, and a division between the continental slope and fjord entrances. Waters from the regional southern freshwater source with origin in the East Greenland Current that rounds Cape Farewell are not observed to enter Baffin Bay. The regional heat source transported by the West Greenland Current is blocked by Southwest Greenland Coastal Water in the south but the deep connections in the north allow warm deep Subpolar Mode Water to enter fjords. Furthermore, we observed cold and relative saline Baffin Bay Polar Water over the inner part of the banks, periodically reaching as far south as 64°N, suggesting the presence of an undescribed southward current at the Southwest Greenland continental shelf.
Published: 2020

27. Review article: How does glacier discharge affect marine biogeochemistry and primary production in the Arctic?

Author: Hopwood, M.J., Carroll, D., Dunse, T., Hodson, A., Holding, J.M., Iriarte, J.L., Ribeiro, S., Achterberg, E.P., Cantoni, C., Carlson, D.F., Chierici, M., Clarke, J.S., Cozzi, S., Fransson, A., Juul-Pedersen, T., Winding, M.H.S., Meire, L., Hopwood, M.J., Carroll, D., Dunse, T., Hodson, A., Holding, J.M., Iriarte, J.L., Ribeiro, S., Achterberg, E.P., Cantoni, C., Carlson, D.F., Chierici, M., Clarke, J.S., Cozzi, S., Fransson, A., Juul-Pedersen, T., Winding, M.H.S., and Meire, L.
Abstract: Freshwater discharge from glaciers is increasing across the Arctic in response to anthropogenic climate change, which raises questions about the potential downstream effects in the marine environment. Whilst a combination of long-term monitoring programmes and intensive Arctic field campaigns have improved our knowledge of glacier–ocean interactions in recent years, especially with respect to fjord/ocean circulation, there are extensive knowledge gaps concerning how glaciers affect marine biogeochemistry and productivity. Following two cross-cutting disciplinary International Arctic Science Committee (IASC) workshops addressing the importance of glaciers for the marine ecosystem, here we review the state of the art concerning how freshwater discharge affects the marine environment with a specific focus on marine biogeochemistry and biological productivity. Using a series of Arctic case studies (Nuup Kangerlua/Godthåbsfjord, Kongsfjorden, Kangerluarsuup Sermia/Bowdoin Fjord, Young Sound and Sermilik Fjord), the interconnected effects of freshwater discharge on fjord–shelf exchange, nutrient availability, the carbonate system, the carbon cycle and the microbial food web are investigated. Key findings are that whether the effect of glacier discharge on marine primary production is positive or negative is highly dependent on a combination of factors. These include glacier type (marine- or land-terminating), fjord–glacier geometry and the limiting resource(s) for phytoplankton growth in a specific spatio-temporal region (light, macronutrients or micronutrients). Arctic glacier fjords therefore often exhibit distinct discharge–productivity relationships, and multiple case-studies must be considered in order to understand the net effects of glacier discharge on Arctic marine ecosystems.
Published: 2020

28. Outcome following local excision of T1 anal cancers—a systematic review

Author: Pedersen, T. B., Kildsig, J., Serup-Hansen, E., Gocht-Jensen, P., Klein, M. F., Pedersen, T. B., Kildsig, J., Serup-Hansen, E., Gocht-Jensen, P., and Klein, M. F.
Abstract: Purpose: In most cases, squamous cell carcinoma of the anus (SCCA) is treated with chemo-radiotherapy preserving sphincter function and offering good long-term survival and low recurrence rates. However, chemo-radiotherapy has several side effects: dyspareunia, impotence, fecal incontinence, pain, and skin symptoms. Small/T1 tumors, without metastatic disease, can be treated with local excision alone. We aimed to systematically review the literature regarding outcome following local excision of T1 SCCA. Methods: PubMed and Embase databases were searched for studies that investigated outcome following local excision of SCCA. Results: Twenty-three studies were included. Twenty of the studies were retrospective, and three studies included more than 100 patients. Most of the studies were published before the 1980s. Overall there was great heterogeneity and missing data across the included studies when comparing patient demographics, resection margins, definitions on tumor location, and outcome. Overall 5-year survival was 69% (95% CI 66–72) following local excision. Overall 5-year recurrence was 37% (95% CI 30–45) following local excision. No complications were reported following local excision. Conclusion: The current literature on outcome following local excision of T1 anal cancers consists predominantly of smaller, retrospective, and heterogenous studies. Overall 5-year survival is acceptable, but worse than following chemo-radiation therapy. However, local excision seems to have no or only few minor complications. Recurrence rates are high. Therefore, a thorough follow-up program is needed when performing local excision as primary treatment for T1 SCCA. There is an evident need for further studies.
Published: 2020

29. Seasonal and spatial patterns of primary production in a high-latitude fjord affected by Greenland Ice Sheet run-off

Author: Holding, J., Markager, S., Juul-Pedersen, T., Paulsen, M.L., Møller, E.F., Meire, L., Sejr, M.K., Holding, J., Markager, S., Juul-Pedersen, T., Paulsen, M.L., Møller, E.F., Meire, L., and Sejr, M.K.
Abstract: Primary production on the coast and in Greenland fjords sustains important local and sustenance fisheries. However, unprecedented melting of the Greenland Ice Sheet (GrIS) is impacting the coastal ocean, and its effects on fjord ecology remain understudied. It has been suggested that as glaciers retreat, primary production regimes may be altered, rendering fjords less productive. Here we investigate patterns of primary productivity in a northeast Greenland fjord (Young Sound, 74∘ N), which receives run-off from the GrIS via land-terminating glaciers. We measured size fractioned primary production during the ice- free season along a spatial gradient of meltwater influence. We found that, apart from a brief under-ice bloom during summer, primary production remains low (between 50 and 200 mg C m−2 d−1) but steady throughout the ice-free season, even into the fall. Low productivity is due to freshwater run-off from land-terminating glaciers causing low light availability and strong vertical stratification limiting nutrient availability. The former is caused by turbid river inputs in the summer restricting phytoplankton biomass to the surface and away from the nitracline. In the outer fjord where turbidity plays less of a role in light limitation, phytoplankton biomass moves higher in the water column in the fall due to the short day length as the sun angle decreases. Despite this, plankton communities in this study were shown to be well adapted to low-light conditions, as evidenced by the low values of saturating irradiance for primary production (5.8–67 µmol photons m−2 s−1). With its low but consistent production across the growing season, Young Sound offers an alternative picture to other more productive fjords which have highly productive spring and late summer blooms and limited fall production. However, patterns of primary productivity observed in Young Sound are not only due to the influence from land-terminating glacie
Published: 2019

30. Seasonal and spatial patterns of primary production in a high-latitude fjord affected by Greenland Ice Sheet run-off

Author: Holding, J., Markager, S., Juul-Pedersen, T., Paulsen, M.L., Møller, E.F., Meire, L., Sejr, M.K., Holding, J., Markager, S., Juul-Pedersen, T., Paulsen, M.L., Møller, E.F., Meire, L., and Sejr, M.K.
Abstract: Primary production on the coast and in Greenland fjords sustains important local and sustenance fisheries. However, unprecedented melting of the Greenland Ice Sheet (GrIS) is impacting the coastal ocean, and its effects on fjord ecology remain understudied. It has been suggested that as glaciers retreat, primary production regimes may be altered, rendering fjords less productive. Here we investigate patterns of primary productivity in a northeast Greenland fjord (Young Sound, 74∘ N), which receives run-off from the GrIS via land-terminating glaciers. We measured size fractioned primary production during the ice- free season along a spatial gradient of meltwater influence. We found that, apart from a brief under-ice bloom during summer, primary production remains low (between 50 and 200 mg C m−2 d−1) but steady throughout the ice-free season, even into the fall. Low productivity is due to freshwater run-off from land-terminating glaciers causing low light availability and strong vertical stratification limiting nutrient availability. The former is caused by turbid river inputs in the summer restricting phytoplankton biomass to the surface and away from the nitracline. In the outer fjord where turbidity plays less of a role in light limitation, phytoplankton biomass moves higher in the water column in the fall due to the short day length as the sun angle decreases. Despite this, plankton communities in this study were shown to be well adapted to low-light conditions, as evidenced by the low values of saturating irradiance for primary production (5.8–67 µmol photons m−2 s−1). With its low but consistent production across the growing season, Young Sound offers an alternative picture to other more productive fjords which have highly productive spring and late summer blooms and limited fall production. However, patterns of primary productivity observed in Young Sound are not only due to the influence from land-terminating glacie
Published: 2019

31. Relation of lipid-lowering therapy to need for aortic valve replacement in patients with asymptomatic mild to moderate aortic stenosis

Author: Greve, A. M. (Anders M.), Bang, C. N. (Casper N.), Boman, K. (Kurt), Egstrup, K. (Kenneth), Kesäniemi, Y. A. (Y. Antero), Ray, S. (Simon), Pedersen, T. R. (Terje R.), Wachtell, K. (Kristian), Greve, A. M. (Anders M.), Bang, C. N. (Casper N.), Boman, K. (Kurt), Egstrup, K. (Kenneth), Kesäniemi, Y. A. (Y. Antero), Ray, S. (Simon), Pedersen, T. R. (Terje R.), and Wachtell, K. (Kristian)
Abstract: In this study, we aimed to determine if pretreatment low-density lipoprotein (LDL) levels and aortic stenosis (AS) severity alter the efficacy of lipid-lowering therapy on reducing aortic valve replacement (AVR). We used 1,687 patients with asymptomatic mild-to-moderate AS, who were randomly assigned (1:1) to 40/10 mg simvastatin/ezetimibe combination versus. placebo in the simvastatin and ezetimibe in aortic stenosis (SEAS) trial. Pretreatment LDL levels (>4 mmol/L) and peak aortic jet velocity (3 m/s) were used to partition study participants into 4 groups, which were followed for a primary endpoint of AVR. Cox regression with tests for interaction was used to study the effect of randomized treatment in each subgroup. During a median follow-up of 4.3 years (IQR 4.2 to 4.7 years; total 7,396 patient-years of follow-up), 478 (28%) patients underwent AVR and 146 (9%) died. A significant risk dependency was detected between simvastatin/ezetimibe combination, LDL levels and mild versus moderate AS on rates of AVR (p = 0.01 for interaction). In stratified analyses, randomized treatment, therefore, reduced the rate of AVR in patients with LDL levels >4 mmol and mild AS at baseline (HR 0.4; 95% CI: 0.2 to 0.9). There was no detectable effect of randomized treatment on the need for AVR in the 3 other participants subgroups. We conclude, that in a secondary analysis from a prospective randomized clinical trial, treatment with simvastatin/ezetimibe combination reduced the need for AVR in a subset of patients with mild AS and high pretreatment LDL levels (Unique identifier on clinicaltrials.gov: NCT00092677).
Published: 2019

32. Clothianidin seed-treatment has no detectable negative impact on honeybee colonies and their pathogens

Author: Osterman, Julia, Wintermantel, D., Locke, B., Jonsson, O., Semberg, E., Onorati, P., Forsgren, E., Rosenkranz, P., Rahbek-Pedersen, T., Bommarco, R., Smith, H.G., Rundlöf, M., de Miranda, J.R., Osterman, Julia, Wintermantel, D., Locke, B., Jonsson, O., Semberg, E., Onorati, P., Forsgren, E., Rosenkranz, P., Rahbek-Pedersen, T., Bommarco, R., Smith, H.G., Rundlöf, M., and de Miranda, J.R.
Abstract: Interactions between multiple stressors have been implicated in elevated honeybee colony losses. Here, we extend our landscape-scale study on the effects of placement at clothianidin seed-treated oilseed rape fields on honeybees with an additional year and new data on honeybee colony development, swarming, mortality, pathogens and immune gene expression. Clothianidin residues in pollen, nectar and honeybees were consistently higher at clothianidin-treated fields, with large differences between fields and years. We found large variations in colony development and microbial composition and no observable negative impact of placement at clothianidin-treated fields. Clothianidin treatment was associated with an increase in brood, adult bees and Gilliamella apicola (beneficial gut symbiont) and a decrease in Aphid lethal paralysis virus and Black queen cell virus - particularly in the second year. The results suggest that at colony level, honeybees are relatively robust to the effects of clothianidin in real-world agricultural landscapes, with moderate, natural disease pressure.
Published: 2019

33. Electron-cyclotron-resonance heating in Wendelstein 7-X: A versatile heating and current-drive method and a tool for in-depth physics studies:Paper

Author: Wolf, R C, Bozhenkov, S, Dinklage, A, Fuchert, G, Kazakov, Y O, Laqua, H P, Marsen, S, Marushchenko, N B, Stange, T, Zanini, M, Abramovic, I, Alonso, A, Baldzuhn, J, Beurskens, M, Beidler, C D, Braune, H, Brunner, K J, Chaudhary, N, Damm, H, Drewelow, P, Gantenbein, G, Gao, Yu, Geiger, J, Hirsch, M, Höfel, U, Jakubowski, M, Jelonnek, J, Jensen, T, Kasparek, W, Knauer, J, Korsholm, Søren Bang, Langenberg, A, Lechte, C, Leipold, F., Mora, H Trimino, Neuner, U, Nielsen, S. K., Moseev, D, Oosterbeek, H, Pablant, N, Pasch, E, Plaum, B, Pedersen, T Sunn, Sitjes, A Puig, Rahbarnia, K, Rasmussen, J., Salewski, M., Schilling, J, Scott, E, Stejner, M., Thomsen, H, Thumm, M, Turkin, Y, Wilde, F, Wolf, R C, Bozhenkov, S, Dinklage, A, Fuchert, G, Kazakov, Y O, Laqua, H P, Marsen, S, Marushchenko, N B, Stange, T, Zanini, M, Abramovic, I, Alonso, A, Baldzuhn, J, Beurskens, M, Beidler, C D, Braune, H, Brunner, K J, Chaudhary, N, Damm, H, Drewelow, P, Gantenbein, G, Gao, Yu, Geiger, J, Hirsch, M, Höfel, U, Jakubowski, M, Jelonnek, J, Jensen, T, Kasparek, W, Knauer, J, Korsholm, Søren Bang, Langenberg, A, Lechte, C, Leipold, F., Mora, H Trimino, Neuner, U, Nielsen, S. K., Moseev, D, Oosterbeek, H, Pablant, N, Pasch, E, Plaum, B, Pedersen, T Sunn, Sitjes, A Puig, Rahbarnia, K, Rasmussen, J., Salewski, M., Schilling, J, Scott, E, Stejner, M., Thomsen, H, Thumm, M, Turkin, Y, and Wilde, F
Abstract: For stellarators, which need no or only small amounts of current drive, electron-cyclotron-resonance heating (ECRH) is a promising heating method even for the envisaged application in a fusion power plant. Wendelstein 7-X (W7-X) is equipped with a steady-state capable ECRH system, operating at 140 GHz, which corresponds to the 2nd cyclotron harmonic of the electrons at a magnetic field of 2.5 T. Ten gyrotrons are operational and already delivered 7 MW to W7-X plasmas. Combined with pellet injection, the highest triple product (0.68 × 1020 keV m−3 s), observed up to now in stellarators, was achieved (Sunn Pedersen et al 2018 Plasma Phys. Control. Fusion 61 014035). For the first time, W7-X plasmas were sustained by 2nd harmonic O-mode heating, approaching the collisionality regime for which W7-X was optimized. Power deposition scans did not show any indication of electron temperature profile resilience. In low-density, low-power plasmas a compensation of the bootstrap current with electron-cyclotron current drive (ECCD) was demonstrated. Sufficiently strong ECCD close to the plasma centre produced periodic internal plasma-crash events, which coincide with the appearance of low order rationals of the rotational transform.
Published: 2019

34. Confirmation of the topology of the Wendelstein 7-X magnetic field to better than 1:100,000

Author: Pedersen, T, Otte, M, Lazerson, S, Helander, P, Bozhenkov, S, Biedermann, C, Klinger, T, Wolf, R, Bosch, H, Abramovic, I, Akaslompolo, S, Aleynikov, P, Aleynikova, K, Ali, A, Alonso, A, Anda, G, Andreeva, T, Ascasibar, E, Baldzuhn, J, Banduch, M, Barbui, T, Beidler, C, Benndorf, A, Beurskens, M, Biel, W, Birus, D, Blackwell, B, Blanco, E, Blatzheim, M, Bluhm, T, Bockenhoff, D, Bolgert, P, Borchardt, M, Bottger, L, Brakel, R, Brandt, C, Brauer, T, Braune, H, Burhenn, R, Buttenschon, B, Bykov, V, Calvo, I, Cappa, A, Carls, A, De Carvalho, B, Castejon, F, Cianciosa, M, Cole, M, Costea, S, Cseh, G, Czarnecka, A, Dal Molin, A, De La Cal, E, De La Pena, A, Degenkolbe, S, Dhard, C, Dinklage, A, Dostal, M, Drevlak, M, Drewelow, P, Drews, P, Dudek, A, Durodie, F, Dzikowicka, A, Von Eeten, P, Effenberg, F, Endler, M, Erckmann, V, Estrada, T, Fahrenkamp, N, Fellinger, J, Feng, Y, Figacz, W, Ford, O, Fornal, T, Frerichs, H, Fuchert, G, Garcia-Munoz, M, Geiger, B, Geiger, J, Gierse, N, Gogoleva, A, Goncalves, B, Gradic, D, Grahl, M, Gross, S, Grote, H, Grulke, O, Guerard, C, Haas, M, Harris, J, Hartfuss, H, Hartmann, D, Hathiramani, D, Hein, B, Heirnich, S, Henneberg, S, Hennig, C, Hernandez, J, Hidalgo, C, Hidalgo, U, Hirsch, M, Hofel, U, Holbe, H, Holting, A, Houry, M, Huber, V, Ionita, C, Israeli, B, Jablonski, S, Jakubowski, M, Van Vuuren, A, Jenzsch, H, Kaczmarczyk, J, Kallmeyer, J, Kamionka, U, Kasahara, H, Kenmochi, N, Kernbichler, W, Killer, C, Kinna, D, Kleiber, R, Knauer, J, Kochl, F, Kocsis, G, Kolesnichenko, Y, Konies, A, Konig, R, Kornejew, P, Koster, F, Kramer-Flecken, A, Krampitz, R, Krawzyk, N, Kremeyer, T, Krychowiak, M, Ksiazek, I, Kubkowska, M, Kuhner, G, Kurki-Suonio, T, Kurz, P, Kuttler, K, Kwak, S, Landreman, M, Langenberg, A, Lapayese, F, Laqua, H, Laube, R, Laux, M, Lentz, H, Lewerentz, M, Liang, Y, Liu, S, Lobsien, J, Cisquella, J, Lopez-Bruna, D, Lore, J, Lorenz, A, Lui, S, Lutsenko, V, Maassberg, H, Maisano-Brown, J, Marchuk, O, Marrelli, L, Marsen, S, Marushchenko, N, Masuzaki, S, Mccarthy, K, Mcneely, P, Medina, F, Milojevic, D, Mishchenko, A, Missal, B, Mittelstaedt, J, Mollen, A, Moncada, V, Monnich, T, Moseev, D, Nagel, M, Naujoks, D, Neilson, G, Neubauer, O, Neuner, U, Ngo, T, Niemann, H, Nuhrenberg, C, Nuhrenberg, J, Ochando, M, Ogawa, K, Ongena, J, Oosterbeek, H, Pablant, N, Pacella, D, Pacios, L, Panadero, N, Pasch, E, Pastor, I, Pavone, A, Pawelec, E, Pedrosa, A, Perseo, V, Peterson, B, Pilopp, D, Pisano, F, Piulatti, M, Plunk, G, Preynas, M, Proll, J, Sitjes, A, Purps, F, Rack, M, Rahbarnia, K, Riemann, J, Risse, K, Rong, P, Rosenberger, J, Rudischhauser, L, Rummel, K, Rummel, T, Runov, A, Rust, N, Ryc, L, Saitoh, H, Satake, S, Schacht, J, Schmitz, O, Schmuck, S, Schneider, B, Schneider, M, Schneider, W, Schrittwieser, R, Schroder, M, Schroder, T, Schroder, R, Schumacher, H, Schweer, B, Seki, R, Sinha, P, Sipilae, S, Slaby, C, Smith, H, Sousa, J, Spring, A, Standley, B, Stange, T, Von Stechow, A, Stephey, L, Stoneking, M, Stridde, U, Suzuki, Y, Svensson, J, Szabolics, T, Szepesi, T, Thomsen, H, Travere, J, Traverso, P, Mora, H, Tsuchiya, H, Tsuijmura, T, Turkin, Y, Valet, S, Van Milligen, B, Vela, L, Velasco, J, Vergote, M, Vervier, M, Viebke, H, Vilbrandt, R, Von Thun, C, Wagner, F, Wang, E, Wang, N, Warmer, F, Wauters, T, Wegener, L, Wegner, T, Weir, G, Wendorf, J, Wenzel, U, Werner, A, Wie, Y, Wiegel, B, Wilde, F, Windisch, T, Winkler, M, Winters, V, Wright, A, Wurden, G, Xanthopoulos, P, Yamada, I, Yasuhara, R, Yokoyama, M, Zhang, D, Zilker, M, Zimbal, A, Zocco, A, Zoletnik, S, Pedersen T. S., Otte M., Lazerson S., Helander P., Bozhenkov S., Biedermann C., Klinger T., Wolf R. C., Bosch H. -S., Abramovic I., Akaslompolo S., Aleynikov P., Aleynikova K., Ali A., Alonso A., Anda G., Andreeva T., Ascasibar E., Baldzuhn J., Banduch M., Barbui T., Beidler C., Benndorf A., Beurskens M., Biel W., Birus D., Blackwell B., Blanco E., Blatzheim M., Bluhm T., Bockenhoff D., Bolgert P., Borchardt M., Bottger L. -G., Brakel R., Brandt C., Brauer T., Braune H., Burhenn R., Buttenschon B., Bykov V., Calvo I., Cappa A., Carls A., De Carvalho B. B., Castejon F., Cianciosa M., Cole M., Costea S., Cseh G., Czarnecka A., Dal Molin A., De La Cal E., De La Pena A., Degenkolbe S., Dhard C. P., Dinklage A., Dostal M., Drevlak M., Drewelow P., Drews P., Dudek A., Durodie F., Dzikowicka A., Von Eeten P., Effenberg F., Endler M., Erckmann V., Estrada T., Fahrenkamp N., Fellinger J., Feng Y., Figacz W., Ford O., Fornal T., Frerichs H., Fuchert G., Garcia-Munoz M., Geiger B., Geiger J., Gierse N., Gogoleva A., Goncalves B., Gradic D., Grahl M., Gross S., Grote H., Grulke O., Guerard C., Haas M., Harris J., Hartfuss H. -J., Hartmann D., Hathiramani D., Hein B., Heirnich S., Henneberg S., Hennig C., Hernandez J., Hidalgo C., Hidalgo U., Hirsch M., Hofel U., Holbe H., Holting A., Houry M., Huber V., Ionita C., Israeli B., Jablonski S., Jakubowski M., Van Vuuren A. J., Jenzsch H., Kaczmarczyk J., Kallmeyer J. -P., Kamionka U., Kasahara H., Kenmochi N., Kernbichler W., Killer C., Kinna D., Kleiber R., Knauer J., Kochl F., Kocsis G., Kolesnichenko Y., Konies A., Konig R., Kornejew P., Koster F., Kramer-Flecken A., Krampitz R., Krawzyk N., Kremeyer T., Krychowiak M., Ksiazek I., Kubkowska M., Kuhner G., Kurki-Suonio T., Kurz P., Kuttler K., Kwak S., Landreman M., Langenberg A., Lapayese F., Laqua H., Laqua H. -P., Laube R., Laux M., Lentz H., Lewerentz M., Liang Y., Liu S., Lobsien J. -F., Cisquella J. L., Lopez-Bruna D., Lore J., Lorenz A., Lui S., Lutsenko V., Maassberg H., Maisano-Brown J., Marchuk O., Marrelli L., Marsen S., Marushchenko N., Masuzaki S., McCarthy K., McNeely P., Medina F., Milojevic D., Mishchenko A., Missal B., Mittelstaedt J., Mollen A., Moncada V., Monnich T., Moseev D., Nagel M., Naujoks D., Neilson G. H., Neubauer O., Neuner U., Ngo T. -T., Niemann H., Nuhrenberg C., Nuhrenberg J., Ochando M., Ogawa K., Ongena J., Oosterbeek H., Pablant N., Pacella D., Pacios L., Panadero N., Pasch E., Pastor I., Pavone A., Pawelec E., Pedrosa A., Perseo V., Peterson B., Pilopp D., Pisano F., Piulatti M. E., Plunk G., Preynas M., Proll J., Sitjes A. P., Purps F., Rack M., Rahbarnia K., Riemann J., Risse K., Rong P., Rosenberger J., Rudischhauser L., Rummel K., Rummel T., Runov A., Rust N., Ryc L., Saitoh H., Satake S., Schacht J., Schmitz O., Schmuck S., Schneider B., Schneider M., Schneider W., Schrittwieser R., Schroder M., Schroder T., Schroder R., Schumacher H. W., Schweer B., Seki R., Sinha P., Sipilae S., Slaby C., Smith H., Sousa J., Spring A., Standley B., Stange T., Von Stechow A., Stephey L., Stoneking M., Stridde U., Suzuki Y., Svensson J., Szabolics T., Szepesi T., Thomsen H., Travere J. -M., Traverso P., Mora H. T., Tsuchiya H., Tsuijmura T., Turkin Y., Valet S., Van Milligen B., Vela L., Velasco J. -L., Vergote M., Vervier M., Viebke H., Vilbrandt R., Von Thun C. P., Wagner F., Wang E., Wang N., Warmer F., Wauters T., Wegener L., Wegner T., Weir G., Wendorf J., Wenzel U., Werner A., Wie Y., Wiegel B., Wilde F., Windisch T., Winkler M., Winters V., Wright A., Wurden G., Xanthopoulos P., Yamada I., Yasuhara R., Yokoyama M., Zhang D., Zilker M., Zimbal A., Zocco A., Zoletnik S., Pedersen, T, Otte, M, Lazerson, S, Helander, P, Bozhenkov, S, Biedermann, C, Klinger, T, Wolf, R, Bosch, H, Abramovic, I, Akaslompolo, S, Aleynikov, P, Aleynikova, K, Ali, A, Alonso, A, Anda, G, Andreeva, T, Ascasibar, E, Baldzuhn, J, Banduch, M, Barbui, T, Beidler, C, Benndorf, A, Beurskens, M, Biel, W, Birus, D, Blackwell, B, Blanco, E, Blatzheim, M, Bluhm, T, Bockenhoff, D, Bolgert, P, Borchardt, M, Bottger, L, Brakel, R, Brandt, C, Brauer, T, Braune, H, Burhenn, R, Buttenschon, B, Bykov, V, Calvo, I, Cappa, A, Carls, A, De Carvalho, B, Castejon, F, Cianciosa, M, Cole, M, Costea, S, Cseh, G, Czarnecka, A, Dal Molin, A, De La Cal, E, De La Pena, A, Degenkolbe, S, Dhard, C, Dinklage, A, Dostal, M, Drevlak, M, Drewelow, P, Drews, P, Dudek, A, Durodie, F, Dzikowicka, A, Von Eeten, P, Effenberg, F, Endler, M, Erckmann, V, Estrada, T, Fahrenkamp, N, Fellinger, J, Feng, Y, Figacz, W, Ford, O, Fornal, T, Frerichs, H, Fuchert, G, Garcia-Munoz, M, Geiger, B, Geiger, J, Gierse, N, Gogoleva, A, Goncalves, B, Gradic, D, Grahl, M, Gross, S, Grote, H, Grulke, O, Guerard, C, Haas, M, Harris, J, Hartfuss, H, Hartmann, D, Hathiramani, D, Hein, B, Heirnich, S, Henneberg, S, Hennig, C, Hernandez, J, Hidalgo, C, Hidalgo, U, Hirsch, M, Hofel, U, Holbe, H, Holting, A, Houry, M, Huber, V, Ionita, C, Israeli, B, Jablonski, S, Jakubowski, M, Van Vuuren, A, Jenzsch, H, Kaczmarczyk, J, Kallmeyer, J, Kamionka, U, Kasahara, H, Kenmochi, N, Kernbichler, W, Killer, C, Kinna, D, Kleiber, R, Knauer, J, Kochl, F, Kocsis, G, Kolesnichenko, Y, Konies, A, Konig, R, Kornejew, P, Koster, F, Kramer-Flecken, A, Krampitz, R, Krawzyk, N, Kremeyer, T, Krychowiak, M, Ksiazek, I, Kubkowska, M, Kuhner, G, Kurki-Suonio, T, Kurz, P, Kuttler, K, Kwak, S, Landreman, M, Langenberg, A, Lapayese, F, Laqua, H, Laube, R, Laux, M, Lentz, H, Lewerentz, M, Liang, Y, Liu, S, Lobsien, J, Cisquella, J, Lopez-Bruna, D, Lore, J, Lorenz, A, Lui, S, Lutsenko, V, Maassberg, H, Maisano-Brown, J, Marchuk, O, Marrelli, L, Marsen, S, Marushchenko, N, Masuzaki, S, Mccarthy, K, Mcneely, P, Medina, F, Milojevic, D, Mishchenko, A, Missal, B, Mittelstaedt, J, Mollen, A, Moncada, V, Monnich, T, Moseev, D, Nagel, M, Naujoks, D, Neilson, G, Neubauer, O, Neuner, U, Ngo, T, Niemann, H, Nuhrenberg, C, Nuhrenberg, J, Ochando, M, Ogawa, K, Ongena, J, Oosterbeek, H, Pablant, N, Pacella, D, Pacios, L, Panadero, N, Pasch, E, Pastor, I, Pavone, A, Pawelec, E, Pedrosa, A, Perseo, V, Peterson, B, Pilopp, D, Pisano, F, Piulatti, M, Plunk, G, Preynas, M, Proll, J, Sitjes, A, Purps, F, Rack, M, Rahbarnia, K, Riemann, J, Risse, K, Rong, P, Rosenberger, J, Rudischhauser, L, Rummel, K, Rummel, T, Runov, A, Rust, N, Ryc, L, Saitoh, H, Satake, S, Schacht, J, Schmitz, O, Schmuck, S, Schneider, B, Schneider, M, Schneider, W, Schrittwieser, R, Schroder, M, Schroder, T, Schroder, R, Schumacher, H, Schweer, B, Seki, R, Sinha, P, Sipilae, S, Slaby, C, Smith, H, Sousa, J, Spring, A, Standley, B, Stange, T, Von Stechow, A, Stephey, L, Stoneking, M, Stridde, U, Suzuki, Y, Svensson, J, Szabolics, T, Szepesi, T, Thomsen, H, Travere, J, Traverso, P, Mora, H, Tsuchiya, H, Tsuijmura, T, Turkin, Y, Valet, S, Van Milligen, B, Vela, L, Velasco, J, Vergote, M, Vervier, M, Viebke, H, Vilbrandt, R, Von Thun, C, Wagner, F, Wang, E, Wang, N, Warmer, F, Wauters, T, Wegener, L, Wegner, T, Weir, G, Wendorf, J, Wenzel, U, Werner, A, Wie, Y, Wiegel, B, Wilde, F, Windisch, T, Winkler, M, Winters, V, Wright, A, Wurden, G, Xanthopoulos, P, Yamada, I, Yasuhara, R, Yokoyama, M, Zhang, D, Zilker, M, Zimbal, A, Zocco, A, Zoletnik, S, Pedersen T. S., Otte M., Lazerson S., Helander P., Bozhenkov S., Biedermann C., Klinger T., Wolf R. C., Bosch H. -S., Abramovic I., Akaslompolo S., Aleynikov P., Aleynikova K., Ali A., Alonso A., Anda G., Andreeva T., Ascasibar E., Baldzuhn J., Banduch M., Barbui T., Beidler C., Benndorf A., Beurskens M., Biel W., Birus D., Blackwell B., Blanco E., Blatzheim M., Bluhm T., Bockenhoff D., Bolgert P., Borchardt M., Bottger L. -G., Brakel R., Brandt C., Brauer T., Braune H., Burhenn R., Buttenschon B., Bykov V., Calvo I., Cappa A., Carls A., De Carvalho B. B., Castejon F., Cianciosa M., Cole M., Costea S., Cseh G., Czarnecka A., Dal Molin A., De La Cal E., De La Pena A., Degenkolbe S., Dhard C. P., Dinklage A., Dostal M., Drevlak M., Drewelow P., Drews P., Dudek A., Durodie F., Dzikowicka A., Von Eeten P., Effenberg F., Endler M., Erckmann V., Estrada T., Fahrenkamp N., Fellinger J., Feng Y., Figacz W., Ford O., Fornal T., Frerichs H., Fuchert G., Garcia-Munoz M., Geiger B., Geiger J., Gierse N., Gogoleva A., Goncalves B., Gradic D., Grahl M., Gross S., Grote H., Grulke O., Guerard C., Haas M., Harris J., Hartfuss H. -J., Hartmann D., Hathiramani D., Hein B., Heirnich S., Henneberg S., Hennig C., Hernandez J., Hidalgo C., Hidalgo U., Hirsch M., Hofel U., Holbe H., Holting A., Houry M., Huber V., Ionita C., Israeli B., Jablonski S., Jakubowski M., Van Vuuren A. J., Jenzsch H., Kaczmarczyk J., Kallmeyer J. -P., Kamionka U., Kasahara H., Kenmochi N., Kernbichler W., Killer C., Kinna D., Kleiber R., Knauer J., Kochl F., Kocsis G., Kolesnichenko Y., Konies A., Konig R., Kornejew P., Koster F., Kramer-Flecken A., Krampitz R., Krawzyk N., Kremeyer T., Krychowiak M., Ksiazek I., Kubkowska M., Kuhner G., Kurki-Suonio T., Kurz P., Kuttler K., Kwak S., Landreman M., Langenberg A., Lapayese F., Laqua H., Laqua H. -P., Laube R., Laux M., Lentz H., Lewerentz M., Liang Y., Liu S., Lobsien J. -F., Cisquella J. L., Lopez-Bruna D., Lore J., Lorenz A., Lui S., Lutsenko V., Maassberg H., Maisano-Brown J., Marchuk O., Marrelli L., Marsen S., Marushchenko N., Masuzaki S., McCarthy K., McNeely P., Medina F., Milojevic D., Mishchenko A., Missal B., Mittelstaedt J., Mollen A., Moncada V., Monnich T., Moseev D., Nagel M., Naujoks D., Neilson G. H., Neubauer O., Neuner U., Ngo T. -T., Niemann H., Nuhrenberg C., Nuhrenberg J., Ochando M., Ogawa K., Ongena J., Oosterbeek H., Pablant N., Pacella D., Pacios L., Panadero N., Pasch E., Pastor I., Pavone A., Pawelec E., Pedrosa A., Perseo V., Peterson B., Pilopp D., Pisano F., Piulatti M. E., Plunk G., Preynas M., Proll J., Sitjes A. P., Purps F., Rack M., Rahbarnia K., Riemann J., Risse K., Rong P., Rosenberger J., Rudischhauser L., Rummel K., Rummel T., Runov A., Rust N., Ryc L., Saitoh H., Satake S., Schacht J., Schmitz O., Schmuck S., Schneider B., Schneider M., Schneider W., Schrittwieser R., Schroder M., Schroder T., Schroder R., Schumacher H. W., Schweer B., Seki R., Sinha P., Sipilae S., Slaby C., Smith H., Sousa J., Spring A., Standley B., Stange T., Von Stechow A., Stephey L., Stoneking M., Stridde U., Suzuki Y., Svensson J., Szabolics T., Szepesi T., Thomsen H., Travere J. -M., Traverso P., Mora H. T., Tsuchiya H., Tsuijmura T., Turkin Y., Valet S., Van Milligen B., Vela L., Velasco J. -L., Vergote M., Vervier M., Viebke H., Vilbrandt R., Von Thun C. P., Wagner F., Wang E., Wang N., Warmer F., Wauters T., Wegener L., Wegner T., Weir G., Wendorf J., Wenzel U., Werner A., Wie Y., Wiegel B., Wilde F., Windisch T., Winkler M., Winters V., Wright A., Wurden G., Xanthopoulos P., Yamada I., Yasuhara R., Yokoyama M., Zhang D., Zilker M., Zimbal A., Zocco A., and Zoletnik S.
Abstract: Fusion energy research has in the past 40 years focused primarily on the tokamak concept, but recent advances in plasma theory and computational power have led to renewed interest in stellarators. The largest and most sophisticated stellarator in the world, Wendelstein 7-X (W7-X), has just started operation, with the aim to show that the earlier weaknesses of this concept have been addressed successfully, and that the intrinsic advantages of the concept persist, also at plasma parameters approaching those of a future fusion power plant. Here we show the first physics results, obtained before plasma operation: that the carefully tailored topology of nested magnetic surfaces needed for good confinement is realized, and that the measured deviations are smaller than one part in 100,000. This is a significant step forward in stellarator research, since it shows that the complicated and delicate magnetic topology can be created and verified with the required accuracy.
Published: 2016

35. Impact of CKD on Household Income

Author: Morton, RL, Schlackow, I, Gray, A, Emberson, J, Herrington, W, Staplin, N, Reith, C, Howard, K, Landray, MJ, Cass, A, Baigent, C, Mihaylova, B, Collins, R, Bray, C, Chen, Y, Baxter, A, Young, A, Hill, M, Knott, C, Feldt-Rasmussen, B, Fellström, B, Grobbee, DE, Grönhagen-Riska, C, Haas, M, Holdaas, H, Hooi, LS, Jiang, L, Kasiske, B, Krairittichai, U, Levin, A, Massy, ZA, Tesar, V, Walker, R, Wanner, C, Wheeler, DC, Wiecek, A, Dasgupta, T, Lewis, D, Mafham, M, Majoni, W, Parish, S, Simpson, D, Strony, J, Musliner, T, Agodoa, L, Armitage, J, Chen, Z, Craig, J, de Zeeuw, D, Gaziano, JM, Grimm, R, Krane, V, Neal, B ; https://orcid.org/0000-0002-0490-7465, Ophascharoensuk, V, Pedersen, T, Sleight, P, Tobert, J, Tomson, C, Morton, RL, Schlackow, I, Gray, A, Emberson, J, Herrington, W, Staplin, N, Reith, C, Howard, K, Landray, MJ, Cass, A, Baigent, C, Mihaylova, B, Collins, R, Bray, C, Chen, Y, Baxter, A, Young, A, Hill, M, Knott, C, Feldt-Rasmussen, B, Fellström, B, Grobbee, DE, Grönhagen-Riska, C, Haas, M, Holdaas, H, Hooi, LS, Jiang, L, Kasiske, B, Krairittichai, U, Levin, A, Massy, ZA, Tesar, V, Walker, R, Wanner, C, Wheeler, DC, Wiecek, A, Dasgupta, T, Lewis, D, Mafham, M, Majoni, W, Parish, S, Simpson, D, Strony, J, Musliner, T, Agodoa, L, Armitage, J, Chen, Z, Craig, J, de Zeeuw, D, Gaziano, JM, Grimm, R, Krane, V, Neal, B ; https://orcid.org/0000-0002-0490-7465, Ophascharoensuk, V, Pedersen, T, Sleight, P, Tobert, J, and Tomson, C
Abstract: © 2017 International Society of Nephrology Introduction: The impact of chronic kidney disease (CKD) on income is unclear. We sought to determine whether CKD severity, serious adverse events, and CKD progression affected household income. Methods: Analyses were undertaken in a prospective cohort of adults with moderate-to-severe CKD in the Study of Heart and Renal Protection (SHARP), with household income information available at baseline screening and study end. Logistic regressions, adjusted for sociodemographic characteristics, smoking, and prior diseases at baseline, estimated associations during the 5-year follow-up, among (i) baseline CKD severity, (ii) incident nonfatal serious adverse events (vascular or cancer), and (iii) CKD treatment modality (predialysis, dialysis, or transplanted) at study end and the outcome “fall into relative poverty.” This was defined as household income <50% of country median income. Results: A total of 2914 SHARP participants from 14 countries were included in the main analysis. Of these, 933 (32%) were in relative poverty at screening; of the remaining 1981, 436 (22%) fell into relative poverty by study end. Compared with participants with stage 3 CKD at baseline, the odds of falling into poverty were 51% higher for those with stage 4 (odds ratio [OR]: 1.51; 95% confidence interval [CI]: 1.09–2.10), 66% higher for those with stage 5 (OR: 1.66; 95% CI: 1.11–2.47), and 78% higher for those on dialysis at baseline (OR: 1.78, 95% CI: 1.22–2.60). Participants with kidney transplant at study end had approximately half the risk of those on dialysis or those with CKD stages 3 to 5. Conclusion: More advanced CKD is associated with increased odds of falling into poverty. Kidney transplantation may have a role in reducing this risk.
Published: 2018

36. Benefit of LDL-C lowering with evolocumab on cardiovascular outcomes by age & sex: an analysis of the FOURIER trial

Author: Sever, P. S., Gouni-Berthold, I., Keech, A., Giugliano, R., Pedersen, T., Wasserman, S., Im, K., Sabatine, M., O'Donoghue, M., Sever, P. S., Gouni-Berthold, I., Keech, A., Giugliano, R., Pedersen, T., Wasserman, S., Im, K., Sabatine, M., and O'Donoghue, M.
Published: 2018

37. Field-level clothianidin exposure affects bumblebees but generally not their pathogens

Author: Wintermantel, D., Locke, B., Andersson, G.K.S., Semberg, E., Forsgren, E., Osterman, Julia, Rahbek Pedersen, T., Bommarco, R., Smith, H.G., Rundlöf, M., de Miranda, J.R., Wintermantel, D., Locke, B., Andersson, G.K.S., Semberg, E., Forsgren, E., Osterman, Julia, Rahbek Pedersen, T., Bommarco, R., Smith, H.G., Rundlöf, M., and de Miranda, J.R.
Abstract: Neonicotinoids are implicated in bee declines and laboratory studies imply that they impair the bee immune system, thereby precipitating a rise in pathogen levels. To establish whether such synergisms reduce bee performance in real-world agricultural landscapes, we analysed the microbial composition of the bumblebee (Bombus terrestris) samples from our recent landscape study on the impacts of field-level clothianidin exposure. We related clothianidin exposure and microbial composition to both individual- and colony-level performance parameters, to better understand the direct and indirect mechanistic effects of neonicotinoid exposure on bumblebees. We show that exposure to clothianidin from seed-coated oilseed rape reduces bumblebee size and numbers, particularly of reproductives. However, exposure does not affect the levels of non-pathogenic bacteria or viruses, nor induce rises in the levels or virulence of intracellular parasites. We conclude that field exposure to the neonicotinoid clothianidin affects bumblebee performance but generally not their pathogenic or beneficial microbiota.
Published: 2018

38. Benefit of LDL-C lowering with evolocumab on cardiovascular outcomes by age & sex: an analysis of the FOURIER trial

Author: Sever, P. S., Gouni-Berthold, I., Keech, A., Giugliano, R., Pedersen, T., Wasserman, S., Im, K., Sabatine, M., O'Donoghue, M., Sever, P. S., Gouni-Berthold, I., Keech, A., Giugliano, R., Pedersen, T., Wasserman, S., Im, K., Sabatine, M., and O'Donoghue, M.
Published: 2018

39. Evolocumab and clinical outcomes in patients with cardiovascular disease

Author: Sabatine, M. S., Giugliano, R. P., Keech, A. C., Honarpour, N., Wiviott, S. D., Murphy, S. A., Kuder, J. F., Wang, H., Liu, T., Wasserman, S. M., Sever, P. S., Pedersen, T. R., Fish, M. P., Abrahamsen, T. E., Im, K., Kanevsky, E., Bonaca, M. P., Lira Pineda, A., Hanlon, K., Knusel, B., Somaratne, R., Kurtz, C., Scott, R., Accini Mendoza, J. L., Amerena, J., Badariene, J., Burgess, L., Ceska, R., Charng, M. J., Choi, D., Cobos, J. L., Dan, G. A., De Ferrari, G. M., Deedwania, P. C., Chopra, V. K., Erglis, A., Ezhov, M. V., Ferreira, J., Filipova, S., Gaciong, Z. A., Pasierski, T., Georgiev, B. G., Gonzalez-Galvez, G., Gouni-Berthold, I., Schaufele, T., Hirayama, A., Huber, K., Rammer, M., Kjaerulf Jensen, H., Wermuth, S., Jiang, L., Jukema, J. W., Kraydashenko, O., Leiter, L. A., Lewis, B. S., Lopez-Miranda, J., Lorenzatti, A. J., Mach, F., Mcadam, B., Nilsson, L., Olsson, A., Rallidis, L., Rogelio, G. G., Kerr Saraiva, J. F., Scheen, A., Schiele, F., Connolly, D., Siu, C. W., Tay, L., Thorgeirsson, G., Tikkanen, M. J., Tokgozoglu, S. L., Toth, K., Viigimaa, M., Wan Ahmad, W. A., Hennekens, C. H., Andreotti, F., Baigent, C., Brown, W. V., Davis, B. R., Newcomer, J. W., Wood, S. K., Larosa, J., Ansell, B., Lowe, C., Zahn, L., Awtry, E., Berger, C., Croce, K., Desai, A., Gelfand, E., Ho, C., Leeman, D., Link, M., Norden, A., Pande, A., Rost, N., Ruberg, F., Silverman, S., Singhal, A., Vita, J., Mackinnon, I., Vogel, D. R., Leon de la Fuente, R., Perna, E., Amuchastegui, M., Pacora, F., Hershson, A., Blumberg, E., Glenny, J. A., Colombo, H., Cuadrado, J. A., Nicolosi, L., Rojas, C. G., Ulla, M. R., Hasbani, E. G., Cuneo, C., Lopez Santi, R. G., Sanabria, H. D., Hrabar, A., Lozada, A., Begg, A., Lehman, S., Wittert, G., Juergens, C., Kostner, K., Beltrame, J., Simpson, R., Sinhal, A., Adams, M., Kritharides, L., Roberts Thomson, P., Cross, D., Thompson, P., Van Gaal, W., Cox, N., Farshid, A., Hammett, C., Garrahy, P., Prasan, A., Horrigan, M., Ebenbichler, C., Hanusch, U., Prager, R., Schernthaner, G., Luger, A., Siostrzonek, P., Toplak, H., Bergler-Klein, J., Paulweber, B., Sinzinger, H., Buysschaert, I., Thoeng, J., Vandekerckhove, H., Catez, E., Verheye, S., Descamps, O., Hoffer, E., Wollaert, B., Chenu, P., van de Borne, P., De Meulemeester, M., Friart, A., Charlier, F., De Raedt, H., Rietzschel, E., Roelandt, R., Lalmand, J., Tavares Russo, L. A., Reis, G., Duarte Barbosa, E. C., Vidotti, M. H., Fernandes Manenti, E. R., Dutra, O., Leaes, P. E., Rech, R. L., Bertolim Precoma, D., Nicolau, J. C., Amoedo, R., Eliaschewitz, F. G., Pereira, A., Kurtz Lisboa, H. R., Soares Piegas, L., Cunha Borges, J. L., Ferreira Rossi, P. R., Pimentel Filho, P., Bodanese, L. C., de Sa Cunha, R., Moura Jorge, J. C., Ardito, W. R., Barroso de Souza, W. K., Hissa, M., Izar, M. C., Manolova, A., Kitova, L., Kinova, E., Tzekova, M., Velchev, V., Tarnovska-Kadreva, R., Gotchev, D., Petrov, I., Raev, D., Trendafilova-Lazarova, D., Yotov, Y., Lazov, P., Rahimi, S., St Amour, E., Constance, C., Pesant, Y., Hess, A., Anderson, T., Sussex, B., Henein, S., Tsoukas, G., Pandey, A. S., Bergeron, J., Hart, R., Gosselin, G., Chehayeb, R., Hamet, P., Hartleib, M., Mukherjee, A., Halperin, F., Petrella, R., Bhargava, R., Lonn, E., Sabbah, E., Bata, I., Cha, J., Gaudet, D., Chapman, K., Murthy, D., Nigro, F., Rupka, D., Gossard, D., Gupta, M., Dowell, A., Mansour, S., Baass, A., Geadah, C., Huynh, T., Peterson, S., Poirier, P., Sabe-Affaki, G., Vertes, G., Crowley, D., Duchesne, L., Pincetti Jofre, C. P., Potthoff Cardenas, S., Conejeros Kindel, C., Saavedra Gajardo, V. A., Lanas Zanetti, F., Sepulveda Varela, P. A., Stockins Fernandez, B. A., Li, W., Li, D., Zhao, S., Li, Z., Wang, J., Yang, Y., Zhang, L., Yang, P., Zhang, X., Huang, H., Xue, L., Zheng, Z., Huang, W., Dai, H., Su, H., Zeng, X., Zheng, Y., Tang, Y., Yao, Z., Sun, Y., Du, Y., Ge, Z., Yan, J., Chen, X., Liu, F., Pei, H., Yang, X., Cui, H., Gu, Y., Yang, Z., Li, J., Lian, Y., Cui, Y., Wang, D., Jiang, J., Li, X., Chen, J., Mo, Z., Xu, P., He, Y., Zhou, C., Qu, P., Zhu, Y., Liu, Y., Shen, X., Gao, X., Terront Lozano, M. A., Moncada Corredor, M. A., Hernandez Triana, E., Botero Lopez, R., Coronel Arroyo, J. A., Quintero Baiz, A. E., Sanchez Vallejo, G., Arana Londono, C., Molina de Salazar, D. I., Castellanos Bueno, R., Manzur Jattin, F., Cure Cure, C. A., Sotomayor Herazo, A., Spinar, J., Hala, T., Machkova, M., Klimsa, Z., Polasek, R., Jerabek, O., Kazdera, P., Pozdisek, Z., Vaclavik, J., Frana, P., Elbl, L., Kucera, D., Kryza, R., Malecha, J., Reichert, P., Sochor, K., Ludka, O., Kellnerova, I., Peterka, K., Zidkova, E., Cech, V., Brabec, T., Fiserova, N., Kvasnicka, J., Rosolova, H., Nemecek, E., Adamkova, V., Dunaj, M., Pojsl, S., Cepelak, M., Podpera, I., Kuchar, L., Rysava, D., Burianova, H., Spinarova, L., Skrobakova, J., Charvat, J., Homza, M., Zemanek, J., Koleckar, P., Karen, I., Krupicka, J., Blaha, V., Matuska, J., Brotanek, J., Cifkova, R., Kuchar, R., Vomacka, Z., Kosek, Z., Hulinsky, V., Krejcova, H., Kuchar, J., Jelinek, Z., Jelinek, P., Markdanner Lindgren, L., Saetre Lihn, A., Korsgaard Thomsen, K., Bronnum-Schou, J., Nielsen, H., Nielsen, T., Egstrup, K., Klausen, I. C., Mickley, H., Hove, J., Jeppesen, J., Melchior, T., Schmidt, E. B., Valter, I., Rosenthal, A., Kaik, J., Kork, A., Alt, I., Strand, J., Nieminen, S., Kahri, J., Suomi, J., Nyman, K., Strandberg, T. E., Piippo, T., Savolainen, M., Vikman, S., Pucheu, Y., Cariou, B., Henry, P., Ferrari, E., Montalescot, G., Ferrieres, J., Roubille, F., Bonnet, B., Angoulvant, D., Range, G., Bammert, A., Delarche, N., Mariat, C., Cayla, G., Durlach, V., Coisne, D., Paillard, F., Rouzier, R., Goralski, M., Khanoyan, P., Cottin, Y., Ziegler, O., Khalife, K., Le Corvoisier, P., Motreff, P., Spaulding, C., Vanbelle, E., Bourhaial, H., Opitz, C., Kahrmann, G., Contzen, C., Appel, K., Schenkenberger, I., Rinke, A., Trenk, D., Maus, O., Karakas, M., Hanefeld, M., Darius, H., Hetzel, G., Munzel, T., Wohrle, J., Stawowy, P., Marten, I., Isermann, B., Kast, P., Vorpahl, M., Bosiljanoff, P., Hengstenberg, C., Kassner, U., Salbach, P., Fischer, M., Steiner, S., Wagner, S., Kraatz, U., von Hodenberg, E., Weyland, K., Mantas, I., Tziakas, D., Bousboulas, S., Patsilinakos, S., Mertzanos, G., Panagoulis, C., Bilianou, H., Skoumas, I., Elisaf, M., Manolis, A., Moschos, N., Kochiadakis, G., Ntaios, G., Richter, D., Athyros, V., Kolovou, G., Danias, P., Melidonis, A., Fan, K. Y. Y., Siu, S. C., Hornyik, A., Lakatos, F., Zilahi, Z., Nagy, K., Laszlo, Z., Peterfai, E., Lupkovics, G., Andreka, P., Merkely, B., Herczeg, B., Piros, G. A., Salamon, C., Mark, L., Papp, A., Szakal, I., Edes, I., Mohacsi, A., Tomcsanyi, J., Hajko, E., Nagy, A., Papp, E., Kiss, R., Karadi, I., Sigurdsson, A., Jain, A., Pai, R., Kothiwale, V., Kulkarni, G., Mahajan, A., Aggarwal, S., Mehta, V., Rajadhyaksha, G., Joshi, A., Khandait, V., Parmar, M., Tyagi, S., Airody Govinda, R., Dwivedi, S. K., Parikh, K., Pothineni, R. B., Solanki, B., O'Donnell, M., Crean, P., Barton, J., Shechter, M., Shotan, A., Klutstein, M., Chorin, E., Gavish, D., Kracoff, O., Atar, S., Rigler, S., Hasin, Y., Schiff, E., Merlini, P., Rapezzi, C., Pirro, M., Gonnelli, S., Floresta, A. M., Mennuni, M., Ardissino, D., Senni, M., Marenzi, G., Marcucci, R., Sampietro, T., Cosmi, F., Perrone Filardi, P., De Caterina, R., Fedele, F., Moretti, L., Biasucci, Luigi Marzio, Ferri, C., Go, Y., Kiyosue, A., Higashi, Y., Tokunaga, T., Kawasaki, T., Sakagami, S., Namba, S., Saku, K., Oku, K., Arakawa, T., Iida, H., Nakamura, Y., Yamamoto, K., Hata, Y., Katsuda, Y., Koga, Y., Shimizu, M., Uehara, H., Kajiyama, S., Okamoto, H., Shinozaki, T., Fujino, Y., Funazaki, T., Higa, N., Kaigawa, K., Koike, A., Nakane, H., Sato, K., Satoh, Y., Shirasawa, K., Sugino, H., Tanabe, J., Uemura, O., Yoshimichi, G., Akai, A., Himeno, H., Inage, T., Inoko, M., Kadokami, T., Noguchi, Y., Yamashita, K., Yasumura, Y., Yuge, M., Hosokawa, S., Kawamitsu, K., Kozuma, K., Matsuo, H., Nakashima, E., Okada, M., Wada, A., Yokoya, K., Iwade, K., Kawabata, K., Tanno, H., Ako, J., Fujita, H., Izumiya, Y., Kanno, M., Nunohiro, T., Ohmura, H., Ueno, T., Kakurina, N., Jasinkevica, I., Stukena, I., Veze, I., Eglite, R., Teterovska, D., Sime, I., Strazdiene, V., Venceviciene, L., Gustiene, O., Radzeviciene-Jurgute, R., Kucinskiene, A., Maskon, O., Lee, C. Y., Erng, T., Gan, H. W., Mohamed Yusof, A. K., Ramanathan, G. L., Liew, H., Lopez Alvarado, A., Nevarez Ruiz, L. A., De los Rios Ibarra, M. O., Bazzoni Ruiz, A. E., Ramos Lopez, G. A., Llamas Esperon, G. A., De la Pena Topete, G. D. J., Violante Ortiz, R. M., Illescas Diaz, J. J., Leon Gonzalez, S., Sanchez Diaz, C. J., Mendez Machado, G. F., Venegas Carrillo, L. A., Aldrete Velasco, J. A., Cardona Munoz, E. G., Leiva Pons, J. L., Perez Alva, J. C., van der Zwaan, C., Oomen, A., van de Wal, R., Magro, M., Boswijk, D., Janus, C., Groutars, R., Tonino, W., Cornel, J. H., Oude Ophuis, A., Troquay, R., Liem, A., Westendorp, I., Van Hessen, M., Lok, D., De Nooijer, C., Den Hartog, F., Van Beek, E., Bendermacher, P., Jansen, R., Romer, T., Rensing, B., Hersbach, F., Herrman, J., Ladyjanskaia, G., Karalis, I., Linssen, G., Bokern, M., Visman, A., Kooij, A., Monajemi, H., Lieverse, A., Baker, J., Tie, S., Risberg, K., Hysing, J., Hoivik, H. O., Norheim, P., Solnor, L., Hovland, A., Kjaernli, T., Jocson, G., Coching, R. M., Batalla, E., Go, A., Habaluyas, R., Barcinas, R., Sy, R. A., Estepar, R. A., Germar, A., Trebacz, J., Szymkowiak, K., Wnetrzak-Michalska, R., Kopaczewski, J., Przekwas-Jaruchowska, M., Kania, G., Zabowka, M., Mirek-Bryniarska, E., Dabrowska, M., Napora, P., Konieczny, M., Spyra, J., Lysek, R., Pijanowski, Z., Grzegorzewski, B., Bednarkiewicz, Z., Kinasz, L., Antkowiak-Piatyszek, K., Stania, K., Szpajer, M., Staneta, P., Skonieczny, G., Ksiezycka-Majczynska, E., Blicharski, T., Piepiorka, M., Wozakowska-Kaplon, B., Zechowicz, T., Ilkowski, J., Lubiszewska, B., Hiczkiewicz, J., Wierzbicka, K., Kosior, D., Garbocz, P., Kubica, J., Raczak, G., Wozniak, I., Cygler, J., Kramarczuk, E., Bystryk, L., Pentela-Nowicka, J., Dabrowski, M., Podolec, P., Zieba, B., Mosiewicz, J., Dubaniewicz, W., Banach, M., Tyszecka, G., Lepich, T., Rychlewska-Hanczewska, A., Guzik, T., Monteiro, P., Pereira, H., Oliveira, L., Matos, P., Soares Goncalves, S., Leitao, A., Vasco Salgado, A., Timoteo, A. 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B., Valter, I., Rosenthal, A., Kaik, J., Kork, A., Alt, I., Strand, J., Nieminen, S., Kahri, J., Suomi, J., Nyman, K., Strandberg, T. 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O., Norheim, P., Solnor, L., Hovland, A., Kjaernli, T., Jocson, G., Coching, R. M., Batalla, E., Go, A., Habaluyas, R., Barcinas, R., Sy, R. A., Estepar, R. A., Germar, A., Trebacz, J., Szymkowiak, K., Wnetrzak-Michalska, R., Kopaczewski, J., Przekwas-Jaruchowska, M., Kania, G., Zabowka, M., Mirek-Bryniarska, E., Dabrowska, M., Napora, P., Konieczny, M., Spyra, J., Lysek, R., Pijanowski, Z., Grzegorzewski, B., Bednarkiewicz, Z., Kinasz, L., Antkowiak-Piatyszek, K., Stania, K., Szpajer, M., Staneta, P., Skonieczny, G., Ksiezycka-Majczynska, E., Blicharski, T., Piepiorka, M., Wozakowska-Kaplon, B., Zechowicz, T., Ilkowski, J., Lubiszewska, B., Hiczkiewicz, J., Wierzbicka, K., Kosior, D., Garbocz, P., Kubica, J., Raczak, G., Wozniak, I., Cygler, J., Kramarczuk, E., Bystryk, L., Pentela-Nowicka, J., Dabrowski, M., Podolec, P., Zieba, B., Mosiewicz, J., Dubaniewicz, W., Banach, M., Tyszecka, G., Lepich, T., Rychlewska-Hanczewska, A., Guzik, T., Monteiro, P., Pereira, H., Oliveira, L., Matos, P., Soares Goncalves, S., Leitao, A., Vasco Salgado, A., Timoteo, A. T., Pintilei, E., Badila, E., Militaru, C., Tudoran, M., Arsenescu-Georgescu, C., Mitu, F., Zdrenghea, D., Lighezan, D., Teodorescu, I., Popescu, M. I., Coman, I., Vintila, M. M., Vishnevsky, A., Lukyanov, Y., Blokhin, A., Kostenko, V., Shvarts, Y., Markov, V., Motylev, I., Dronov, D., Sherenkov, A., Barbarash, O., Shutemova, E., Bolshakova, O., Kobalava, Z., Voevoda, M., Treshkur, T., Zrazhevskiy, K., Pimenov, L., Solovev, O., Tarasov, N., Arkhipov, M., Freidlin, M., Shalaev, S., Yakhontova, P., Shustov, S., Goloshchekin, B., Panov, A., Bart, B., Bubnova, M., Gordeev, I., Osipova, I., Tereshenko, S., Solovieva, E., Meshkov, A., Zateyshchikov, D., Tan, J. L., Subramaniam, T., Pella, D., Fulop, P., Antalik, L., Dzupina, A., Banikova, A., Sosovec, D., Urgeova, L., Mazur, J., Hranai, M., Banik, M., Vinanska, D., Lennerova, J., Kovar, F., Pastrnakova, E., Uhliar, R., Blasko, P., Gonsorcik, J., Lukacova, J., Oriesek, R., Hatalova, K., du Toit, M., Ebrahim, I., Vawda, G., Lipschitz, S., Blignaut, S., Engelbrecht, J., Coetzer, T. F., Pretorius, M., Urbach, D., Badat, A., Pillay, S., Van Zyl, L., Abelson, M., van der Walt, E., Moodley, R., Jacovides, A., Oosthuysen, W. M., Klug, E., Lottering, H., Kok, J., Saaiman, J., Dawood, S., De Jong, D. M., Kapp, C., Makotoko, E., Bayat, J., Sarvan, M., Vally, T., Stapelberg, A., Kim, M., Bae, J., Cho, Y., Kim, S., Han, K. H., Her, S., Kim, B., Lee, S., Hong, B., Kim, W., Rha, S., Jeong, M., Shin, G. J., Vida Gutierrez, M., Valdes Chavarri, M., Pinto Sala, X., Gonzalez Juanatey, J. R., Civeira Murillo, F., Zamorano Gomez, J. L., Lekuona Goya, I., Iniguez Romo, A., Cordero Fort, A., Ascaso Gimilio, J. F., Millan Nunez-Cortes, J., Lindholm, C., Soderberg, S., Suutari, A., Berglund, S., Mooe, T., Kusiak, D., Bandh, S., Dahlen, G., Olsson, S., Witt, N., Tyden, P., Johansson, P., Cizinsky, S., Falck, G., Pettersson, S. I., Rasmanis, G., Ostergren, J., Moccetti, T., Beer, H. J., Eberli, F., Krahenbuhl, S., Linka, A., Ackermann, D., Michel, P., Yeh, H., Tsai, C. F., Wu, C., Hsia, C., Juang, J., Hsieh, I., Lai, W., Huang, C., Hsieh, Y., Sahin, T., Duzenli, M., Yigit, Z., Demir, M., Yilmaz, M. B., Muderrisoglu, I. H., Kirma, C., Ercan, E., Kayikcioglu, L., Balbay, Y., Lymar, I., Kulynych, O., Prokhorov, O., Karpenko, O., Vakaliuk, I., Stanislavchuk, M., Korzh, O., Rudyk, I., Zhurba, S., Svishchenko, Y., Tseluyko, V., Gyrina, O., Reshotko, D., Kopytsya, M., Volkov, V., Myshanych, G., Rebrov, B., Rishko, M., Rudenko, L., Shatylo, V., Parkhomenko, O., Yena, L., Golovchenko, O., Sorokina, I., Malynovsky, Y., Ivan, P., Blagden, M., Dear, H., Mathew, A., Lagocki, S., Kondagunta, V., Ahsan, A., Mckinnon, C., Douglas, F., Thom, S., Fiore, G., Caulfield, M., Lynch, M., Thomas, H., Bain, S., Hall, A., Mcnally, D., Fisher, M., Keeling, P., Al-Bahrani, A., Lip, G., Ellery, A., Purohit, J., Travill, C., Cappuccio, F., Davis, G., Gaunt, R., Adlam, D., Asamoah, N., Jaafar, F., Mccormack, T., Jupp, B., Pye, M., Ainsworth, P., Chauhan, A., Paul, N., Fairlie, H., Fox, C., Muzulu, S., Trevelyan, J., Aggarwal, R., Issa, B., Saravanan, P., Cruickshank, K., Gorog, D., Heller, S., Newby, D., Nicolson, A., Hare, P. O., Donnelly, P., Rutherfurd, S., de Belder, M., Finlayson, J., Harvey, J., Hoye, A., Kingston, D., Sarkar, D., Negahban, A., Webster, J., Wyatt, N., Muir, S., Cummings, M., Mackenzie, I., Senior, R., Capps, N., Fotherby, K., Mcintyre, H., Aldegather, J., Dixon, L., Saksena, R., Butler, R., Ramstad, D., Pierpont, B., Levinson, D., Mohammed, A., Haddad, T., Goel, A., Dave, K., Haught, W. H., Desire, A., Hershon, K., Napoli, M., Tami, L., Rothschild, R., Khurana, S., Gupta, D., Cheung, D., Hearne, S., Grubb, S., Miller, A., Baird, I., Marcus, A., Srivastava, S., Forgosh, L., Fritz, R., Mays, M., Bertolet, B., Reddy, J., Khan, M., Nakhle, S., Dill, S., Fishbein, G., Khan, B., Marais, H., Reschak, M., Malone, M., Nadar, V., Whitney, R., Reichman, A., Reyes, H., El Shahawy, M., Rabinowitz, A., Weinstein, D., Farhat, N., Onyema, D., Potu, R., Runquist, L., Barnum, O., Crater, T., Fialkow, J., Shah, A., Thompson, C., Wiseman, A., Doyle, T., Henderson, D., Herzog, W., Schnitzler, R., Carr, K., Davis, M., Nagajothi, N., Olsen, S., Rogers, W., Rubino, J., Singh, I., Tarleton, G., Bhagwat, R., Clardy, D., Jardula, M., Robinson, J., Torres, M., Vijay, N., Farris, N., Lillo, J., Moriarty, P., Recknor, C., Berlacher, P., Christensen, T., Gabra, N., Issa, M., Janik, M., Lawless, A., Molter, D., Stout, E., Brezina, B., Claxton, E., Linsky, R., Poock, J., Remler, R., Roseman, H., Schramm, E., Al-Joundi, T., Amin, J., Hitchcock, J., Isserman, S., Kirstein, J., Rider, J., Shalek, M., Sherman, H., Bernstein, M., Chandra, L., Hatharasinghe, R., Ibrahim, H., Iteld, B., Linzmeyer, K., Seaton, B., Zeig, S., Christofides, E., Dunbar, R., Griffin, S., Kohli, N., Koren, M., Pharr, W., Purdy, D., Spencer, R., Yeoman, G., Banerjee, S., Cheek, H. B., Engel, E., Hamroff, G., Huling, R., Kozlowski, L., Levin, P., Makam, S., Meengs, M., Bhushan, R., Erickson, B., Herman, L., Lo, E., Mcdowell, E., Mcgrew, F., Miller, M., Ord, J., Webel, R., Wilhoit, G., Wise, J., Yang, E., Budoff, M., Collins, J., Dauber, I., Dobkin, L., Focil, A., Gandy, W., Pasquini, J., Ramos, M., Rodriguez, D., Rosenson, R., Sanford, K., Schlau, A., Snyder, B., Stonesifer, L., Tang, A., De Souza, J., Elam, M., French, J., Guyton, J., Hage Korban, E., Kereiakes, D., King, M., Loh, I., Navarro, J., Simons, R., Tobin, T., Younis, L., Aboufakher, R., Baldari, D., Ballantyne, C., Broughton, R., Eaton, C., Johnston, J., Simon, W., Thomson, S., Vora, K., Youngman, D., Alzohaili, O., Auerbach, E., Brown, C., Burrough, B., Chen, Y., Gilpatrick, M., Landzberg, J., Mitchell, C., Rice, L., Rubenfire, M., Sofley, C. W., Strobl, D., Atassi, K., Davila, W., Diogo, J., Fagan, T., Joffe, I., Krishna, J., Osea, E., Penny, W., Rowe, W., Shapiro, M., Welker, J., Benton, R., Dobratz, D., Fortuin, F., Graham, J., Henry, B., Kusnick, B., Lutskiy, M., Mcrae, A., Saway, W., Scott, J., Shah, M., Weinberg, B., Zarich, S., Acheatel, R., Case, C., Earl, J., Fernandez, S., Giugliano, G., Handelsman, Y., Hermany, P., Holder, S., Kashyap, M., Khan, A., Lader, E., Peniston, J., Raoof, T., Sacco, J., Shore, K., Spriggs, D., Stringam, S., Tahirkheli, N., Delgado, E., Derian, W., Greenwald, J., Harris, M., Jackson, R., Marhefka, G., Mcelveen, W., Mooss, A., Morris, P., Murray, J., Pearlstein, P., Raisinghani, A., Rezkalla, S., Sakhrani, L., Schreibman, D., Shaoulian, E., Steinsapir, J., Yataco, A., De La Cruz, A., Fredrick, M., Goldenberg, E., Lee, D., Mccullum, K., Mclellan, B., Stephens, L., Wilson, S., Alfieri, A., Mandviwala, M., Orourke, D., Samal, A., Schmedtje, J., Waxman, F., Carhart, R., Clements, B., Dyke, C., Ghali, J., Gruberg, L., Hack, T., Jehle, A., Pogue, B., Schooley, C., Shifrin, G., and Biasucci L. M. (ORCID:0000-0002-6921-6497)
Abstract: BACKGROUND Evolocumab is a monoclonal antibody that inhibits proprotein convertase subtilisin-kexin type 9 (PCSK9) and lowers low-density lipoprotein (LDL) cholesterol levels by approximately 60%. Whether it prevents cardiovascular events is uncertain. METHODS We conducted a randomized, double-blind, placebo-controlled trial involving 27,564 patients with atherosclerotic cardiovascular disease and LDL cholesterol levels of 70 mg per deciliter (1.8 mmol per liter) or higher who were receiving statin therapy. Patients were randomly assigned to receive evolocumab (either 140 mg every 2 weeks or 420 mg monthly) or matching placebo as subcutaneous injections. The primary efficacy end point was the composite of cardiovascular death, myocardial infarction, stroke, hospitalization for unstable angina, or coronary revascularization. The key secondary efficacy end point was the composite of cardiovascular death, myocardial infarction, or stroke. The median duration of follow-up was 2.2 years. RESULTS At 48 weeks, the least-squares mean percentage reduction in LDL cholesterol levels with evolocumab, as compared with placebo, was 59%, from a median baseline value of 92 mg per deciliter (2.4 mmol per liter) to 30 mg per deciliter (0.78 mmol per liter) (P<0.001). Relative to placebo, evolocumab treatment significantly reduced the risk of the primary end point (1344 patients [9.8%] vs. 1563 patients [11.3%]; hazard ratio, 0.85; 95% confidence interval [CI], 0.79 to 0.92; P<0.001) and the key secondary end point (816 [5.9%] vs. 1013 [7.4%]; hazard ratio, 0.80; 95% CI, 0.73 to 0.88; P<0.001). The results were consistent across key subgroups, including the subgroup of patients in the lowest quartile for baseline LDL cholesterol levels (median, 74 mg per deciliter [1.9 mmol per liter]). There was no significant difference between the study groups with regard to adverse events (including new-onset diabetes and neurocognitive events), with the exception of injection-site reacti
Published: 2017

40. Major results from the first plasma campaign of the Wendelstein 7-X stellarator

Author: Wolf, R.C., Ali, A., Alonso, A., Baldzuhn, J., Beidler, C., Beurskens, M., Biedermann, C., Bosch, H.-S., Bozhenkov, S., Brakel, R., Dinklage, A., Feng, Y., Fuchert, G., Geiger, J., Grulke, O., Helander, P., Hirsch, M., Höfel, U., Jakubowski, M., Knauer, J., Kocsis, G., König, R., Kornejew, P., Krämer-Flecken, A., Krychowiak, M., Landreman, M., Langenberg, A., Laqua, H.P., Lazerson, S., Maaßberg, H., Marsen, S., Marushchenko, M., Moseev, D., Niemann, H., Pablant, N., Pasch, E., Rahbarnia, K., Schlisio, G., Stange, T., Sunn Pedersen, T., Svensson, J., Szepesi, T., Trimino Mora, H., Turkin, Y., Wauters, T., Weir, G., Wenzel, U., Windisch, T., Wurden, G., Zhang, D., Abramovic, I., Äkäslompolo, S., Aleynikov, P., Aleynikova, K., Alzbutas, R., Anda, G., Andreeva, T., Ascasibar, E., Assmann, J., Baek, S.-G., Banduch, M., Barbui, T., Barlak, M., Baumann, K., Behr, W., Benndorf, A., Bertuch, O., Biel, W., Birus, D., Blackwell, B., Blanco, E., Blatzheim, M., Bluhm, T., Böckenhoff, D., Bolgert, P., Borchardt, M., Borsuk, V., Boscary, J., Böttger, L.-G., Brand, H., Brandt, Ch., Bräuer, T., Braune, H., Brezinsek, S., Brunner, K.-J., Brünner, B., Burhenn, R., Buttenschön, B., Bykov, V., Calvo, I., Cannas, B., Cappa, A., Carls, A., Carraro, L., Carvalho, B., Castejon, F., Charl, A., Chernyshev, F., Cianciosa, M., Citarella, R., Ciupiński, Ł., Claps, G., Cole, M., Cole, M.J., Cordella, F., Cseh, G., Czarnecka, A., Czermak, A., Czerski, K., Czerwinski, M., Czymek, G., da Molin, A., da Silva, A., Dammertz, G., Danielson, J., de la Pena, A., Degenkolbe, S., Denner, P., Dhard, D.P., Dostal, M., Drevlak, M., Drewelow, P., Drews, Ph., Dudek, A., Dundulis, G., Durodie, F., van Eeten, P., Effenberg, F., Ehrke, G., Endler, M., Ennis, D., Erckmann, E., Esteban, H., Estrada, T., Fahrenkamp, N., Feist, J.-H., Fellinger, J., Fernandes, H., Fietz, W.H., Figacz, W., Fontdecaba, J., Ford, O., Fornal, T., Frerichs, H., Freund, A., Führer, M., Funaba, T., Galkowski, A., Gantenbein, G., Gao, Y., García Regaña, J., Garcia-Munoz, M., Gates, D., Gawlik, G., Geiger, B., Giannella, V., Gierse, N., Gogoleva, A., Goncalves, B., Goriaev, A., Gradic, D., Grahl, M., Green, J., Grosman, A., Grote, H., Gruca, M., Guerard, C., Haiduk, L., Han, X., Harberts, F., Harris, J.H., Hartfuß, H.-J., Hartmann, D., Hathiramani, D., Hein, B., Heinemann, B., Heitzenroeder, P., Henneberg, S., Hennig, C., Hernandez Sanchez, J., Hidalgo, C., Hölbe, H., Hollfeld, K.P., Hölting, A., Höschen, D., Houry, M., Howard, J., Huang, X., Huber, M., Huber, V., Hunger, H., Ida, K., Ilkei, T., Illy, S., Israeli, B., Ivanov, A., Jablonski, S., Jagielski, J., Jelonnek, J., Jenzsch, H., Junghans, P., Kacmarczyk, J., Kaliatka, T., Kallmeyer, J.-P., Kamionka, U., Karalevicius, R., Kasahara, H., Kasparek, W., Kenmochi, N., Keunecke, M., Khilchenko, A., Kinna, D., Kleiber, R., Klinger, T., Knaup, M., Kobarg, Th., Köchl, F., Kolesnichenko, Y., Könies, A., Köppen, M., Koshurinov, J., Koslowski, R., Köster, F., Koziol, R., Krämer, M., Krampitz, R., Kraszewsk, P., Krawczyk, N., Kremeyer, T., Krings, Th., Krom, J., Krzesinski, G., Ksiazek, I., Kubkowska, M., Kühner, G., Kurki-Suonio, T., Kwak, S., Lang, R., Langish, S., Laqua, H., Laube, R., Lechte, C., Lennartz, M., Leonhardt, W., Lewerentz, L., Liang, Y., Linsmeier, Ch., Liu, S., Lobsien, J.-F., Loesser, D., Loizu Cisquella, J., Lore, J., Lorenz, A., Losert, M., Lubyako, L., Lücke, A., Lumsdaine, A., Lutsenko, V., Majano-Brown, J., Marchuk, O., Mardenfeld, M., Marek, P., Massidda, S., Masuzaki, S., Maurer, D., McCarthy, K., McNeely, P., Meier, A., Mellein, D., Mendelevitch, B., Mertens, Ph., Mikkelsen, D., Mishchenko, O., Missal, B., Mittelstaedt, J., Mizuuchi, T., Mollen, A., Moncada, V., Mönnich, T., Morizaki, T., Munk, R., Murakami, S., Musielok, F., Náfrádi, G., Nagel, M., Naujoks, D., Neilson, H., Neubauer, O., Neuner, U., Ngo, T., Nocentini, R., Nührenberg, C., Nührenberg, J., Obermayer, S., Offermanns, G., Ogawa, K., Ongena, J., Oosterbeek, J.W., Orozco, G., Otte, M., Pacios Rodriguez, L., Pan, W., Panadero, N., Panadero Alvarez, N., Panin, A., Papenfuß, D., Paqay, S., Pavone, A., Pawelec, E., Pelka, G., Peng, X., Perseo, V., Peterson, B., Pieper, A., Pilopp, D., Pingel, S., Pisano, F., Plaum, B., Plunk, G., Povilaitis, M., Preinhaelter, J., Proll, J., Puiatti, M.-E., Puig Sitjes, A., Purps, F., Rack, M., Récsei, S., Reiman, A., Reiter, D., Remppel, F., Renard, S., Riedl, R., Riemann, J., Rimkevicius, S., Riße, K., Rodatos, A., Röhlinger, H., Romé, M., Rong, P., Roscher, H.-J., Roth, B., Rudischhauser, L., Rummel, K., Rummel, T., Runov, A., Rust, N., Ryc, L., Ryosuke, S., Sakamoto, R., Samartsev, A., Sanchez, M., Sano, F., Satake, S., Satheeswaran, G., Schacht, J., Schauer, F., Scherer, T., Schlaich, A., Schlüter, K.-H., Schmitt, J., Schmitz, H., Schmitz, O., Schmuck, S., Schneider, M., Schneider, W., Scholz, M., Scholz, P., Schrittwieser, R., Schröder, M., Schröder, T., Schroeder, R., Schumacher, H., Schweer, B., Shanahan, B., Shikhovtsev, I.V., Sibilia, M., Sinha, P., Sipliä, S., Skodzik, J., Slaby, C., Smith, H., Spiess, W., Spong, D.A., Spring, A., Stadler, R., Standley, B., Stephey, L., Stoneking, M., Stridde, U., Sulek, Z., Surko, C., Suzuki, Y., Szabó, V., Szabolics, T., Szökefalvi-Nagy, Z., Tamura, N., Terra, A., Terry, J., Thomas, J., Thomsen, H., Thumm, M., von Thun, C.P., Timmermann, D., Titus, P., Toi, K., Travere, J.M., Traverso, P., Tretter, J., Tsuchiya, H., Tsujimura, T., Tulipán, S., Turnyanskiy, M., Unterberg, B., Urban, J., Urbonavicius, E., Vakulchyk, I., Valet, S., van Millingen, B., Vela, L., Velasco, J.-L., Vergote, M., Vervier, M., Vianello, N., Viebke, H., Vilbrandt, R., Vorkörper, A., Wadle, S., Wagner, F., Wang, E., Wang, N., Warmer, F., Wegener, L., Weggen, J., Wei, Y., Wendorf, J., Werner, A., Wiegel, B., Wilde, F., Winkler, E., Winters, V., Wolf, S., Wolowski, J., Wright, A., Xanthopoulos, P., Yamada, H., Yamada, I., Yasuhara, R., Yokoyama, M., Zajac, J., Zarnstorff, M., Zeitler, A., Zhang, H., Zhu, J., Zilker, M., Zimbal, A., Zocco, A., Zoletnik, S., Zuin, M., Wolf, R.C., Ali, A., Alonso, A., Baldzuhn, J., Beidler, C., Beurskens, M., Biedermann, C., Bosch, H.-S., Bozhenkov, S., Brakel, R., Dinklage, A., Feng, Y., Fuchert, G., Geiger, J., Grulke, O., Helander, P., Hirsch, M., Höfel, U., Jakubowski, M., Knauer, J., Kocsis, G., König, R., Kornejew, P., Krämer-Flecken, A., Krychowiak, M., Landreman, M., Langenberg, A., Laqua, H.P., Lazerson, S., Maaßberg, H., Marsen, S., Marushchenko, M., Moseev, D., Niemann, H., Pablant, N., Pasch, E., Rahbarnia, K., Schlisio, G., Stange, T., Sunn Pedersen, T., Svensson, J., Szepesi, T., Trimino Mora, H., Turkin, Y., Wauters, T., Weir, G., Wenzel, U., Windisch, T., Wurden, G., Zhang, D., Abramovic, I., Äkäslompolo, S., Aleynikov, P., Aleynikova, K., Alzbutas, R., Anda, G., Andreeva, T., Ascasibar, E., Assmann, J., Baek, S.-G., Banduch, M., Barbui, T., Barlak, M., Baumann, K., Behr, W., Benndorf, A., Bertuch, O., Biel, W., Birus, D., Blackwell, B., Blanco, E., Blatzheim, M., Bluhm, T., Böckenhoff, D., Bolgert, P., Borchardt, M., Borsuk, V., Boscary, J., Böttger, L.-G., Brand, H., Brandt, Ch., Bräuer, T., Braune, H., Brezinsek, S., Brunner, K.-J., Brünner, B., Burhenn, R., Buttenschön, B., Bykov, V., Calvo, I., Cannas, B., Cappa, A., Carls, A., Carraro, L., Carvalho, B., Castejon, F., Charl, A., Chernyshev, F., Cianciosa, M., Citarella, R., Ciupiński, Ł., Claps, G., Cole, M., Cole, M.J., Cordella, F., Cseh, G., Czarnecka, A., Czermak, A., Czerski, K., Czerwinski, M., Czymek, G., da Molin, A., da Silva, A., Dammertz, G., Danielson, J., de la Pena, A., Degenkolbe, S., Denner, P., Dhard, D.P., Dostal, M., Drevlak, M., Drewelow, P., Drews, Ph., Dudek, A., Dundulis, G., Durodie, F., van Eeten, P., Effenberg, F., Ehrke, G., Endler, M., Ennis, D., Erckmann, E., Esteban, H., Estrada, T., Fahrenkamp, N., Feist, J.-H., Fellinger, J., Fernandes, H., Fietz, W.H., Figacz, W., Fontdecaba, J., Ford, O., Fornal, T., Frerichs, H., Freund, A., Führer, M., Funaba, T., Galkowski, A., Gantenbein, G., Gao, Y., García Regaña, J., Garcia-Munoz, M., Gates, D., Gawlik, G., Geiger, B., Giannella, V., Gierse, N., Gogoleva, A., Goncalves, B., Goriaev, A., Gradic, D., Grahl, M., Green, J., Grosman, A., Grote, H., Gruca, M., Guerard, C., Haiduk, L., Han, X., Harberts, F., Harris, J.H., Hartfuß, H.-J., Hartmann, D., Hathiramani, D., Hein, B., Heinemann, B., Heitzenroeder, P., Henneberg, S., Hennig, C., Hernandez Sanchez, J., Hidalgo, C., Hölbe, H., Hollfeld, K.P., Hölting, A., Höschen, D., Houry, M., Howard, J., Huang, X., Huber, M., Huber, V., Hunger, H., Ida, K., Ilkei, T., Illy, S., Israeli, B., Ivanov, A., Jablonski, S., Jagielski, J., Jelonnek, J., Jenzsch, H., Junghans, P., Kacmarczyk, J., Kaliatka, T., Kallmeyer, J.-P., Kamionka, U., Karalevicius, R., Kasahara, H., Kasparek, W., Kenmochi, N., Keunecke, M., Khilchenko, A., Kinna, D., Kleiber, R., Klinger, T., Knaup, M., Kobarg, Th., Köchl, F., Kolesnichenko, Y., Könies, A., Köppen, M., Koshurinov, J., Koslowski, R., Köster, F., Koziol, R., Krämer, M., Krampitz, R., Kraszewsk, P., Krawczyk, N., Kremeyer, T., Krings, Th., Krom, J., Krzesinski, G., Ksiazek, I., Kubkowska, M., Kühner, G., Kurki-Suonio, T., Kwak, S., Lang, R., Langish, S., Laqua, H., Laube, R., Lechte, C., Lennartz, M., Leonhardt, W., Lewerentz, L., Liang, Y., Linsmeier, Ch., Liu, S., Lobsien, J.-F., Loesser, D., Loizu Cisquella, J., Lore, J., Lorenz, A., Losert, M., Lubyako, L., Lücke, A., Lumsdaine, A., Lutsenko, V., Majano-Brown, J., Marchuk, O., Mardenfeld, M., Marek, P., Massidda, S., Masuzaki, S., Maurer, D., McCarthy, K., McNeely, P., Meier, A., Mellein, D., Mendelevitch, B., Mertens, Ph., Mikkelsen, D., Mishchenko, O., Missal, B., Mittelstaedt, J., Mizuuchi, T., Mollen, A., Moncada, V., Mönnich, T., Morizaki, T., Munk, R., Murakami, S., Musielok, F., Náfrádi, G., Nagel, M., Naujoks, D., Neilson, H., Neubauer, O., Neuner, U., Ngo, T., Nocentini, R., Nührenberg, C., Nührenberg, J., Obermayer, S., Offermanns, G., Ogawa, K., Ongena, J., Oosterbeek, J.W., Orozco, G., Otte, M., Pacios Rodriguez, L., Pan, W., Panadero, N., Panadero Alvarez, N., Panin, A., Papenfuß, D., Paqay, S., Pavone, A., Pawelec, E., Pelka, G., Peng, X., Perseo, V., Peterson, B., Pieper, A., Pilopp, D., Pingel, S., Pisano, F., Plaum, B., Plunk, G., Povilaitis, M., Preinhaelter, J., Proll, J., Puiatti, M.-E., Puig Sitjes, A., Purps, F., Rack, M., Récsei, S., Reiman, A., Reiter, D., Remppel, F., Renard, S., Riedl, R., Riemann, J., Rimkevicius, S., Riße, K., Rodatos, A., Röhlinger, H., Romé, M., Rong, P., Roscher, H.-J., Roth, B., Rudischhauser, L., Rummel, K., Rummel, T., Runov, A., Rust, N., Ryc, L., Ryosuke, S., Sakamoto, R., Samartsev, A., Sanchez, M., Sano, F., Satake, S., Satheeswaran, G., Schacht, J., Schauer, F., Scherer, T., Schlaich, A., Schlüter, K.-H., Schmitt, J., Schmitz, H., Schmitz, O., Schmuck, S., Schneider, M., Schneider, W., Scholz, M., Scholz, P., Schrittwieser, R., Schröder, M., Schröder, T., Schroeder, R., Schumacher, H., Schweer, B., Shanahan, B., Shikhovtsev, I.V., Sibilia, M., Sinha, P., Sipliä, S., Skodzik, J., Slaby, C., Smith, H., Spiess, W., Spong, D.A., Spring, A., Stadler, R., Standley, B., Stephey, L., Stoneking, M., Stridde, U., Sulek, Z., Surko, C., Suzuki, Y., Szabó, V., Szabolics, T., Szökefalvi-Nagy, Z., Tamura, N., Terra, A., Terry, J., Thomas, J., Thomsen, H., Thumm, M., von Thun, C.P., Timmermann, D., Titus, P., Toi, K., Travere, J.M., Traverso, P., Tretter, J., Tsuchiya, H., Tsujimura, T., Tulipán, S., Turnyanskiy, M., Unterberg, B., Urban, J., Urbonavicius, E., Vakulchyk, I., Valet, S., van Millingen, B., Vela, L., Velasco, J.-L., Vergote, M., Vervier, M., Vianello, N., Viebke, H., Vilbrandt, R., Vorkörper, A., Wadle, S., Wagner, F., Wang, E., Wang, N., Warmer, F., Wegener, L., Weggen, J., Wei, Y., Wendorf, J., Werner, A., Wiegel, B., Wilde, F., Winkler, E., Winters, V., Wolf, S., Wolowski, J., Wright, A., Xanthopoulos, P., Yamada, H., Yamada, I., Yasuhara, R., Yokoyama, M., Zajac, J., Zarnstorff, M., Zeitler, A., Zhang, H., Zhu, J., Zilker, M., Zimbal, A., Zocco, A., Zoletnik, S., and Zuin, M.
Abstract: After completing the main construction phase of Wendelstein 7-X (W7-X) and successfully commissioning the device, first plasma operation started at the end of 2015. Integral commissioning of plasma start-up and operation using electron cyclotron resonance heating (ECRH) and an extensive set of plasma diagnostics have been completed, allowing initial physics studies during the first operational campaign. Both in helium and hydrogen, plasma breakdown was easily achieved. Gaining experience with plasma vessel conditioning, discharge lengths could be extended gradually. Eventually, discharges lasted up to 6 s, reaching an injected energy of 4 MJ, which is twice the limit originally agreed for the limiter configuration employed during the first operational campaign. At power levels of 4 MW central electron densities reached 3 × 1019 m−3, central electron temperatures reached values of 7 keV and ion temperatures reached just above 2 keV. Important physics studies during this first operational phase include a first assessment of power balance and energy confinement, ECRH power deposition experiments, 2nd harmonic O-mode ECRH using multi-pass absorption, and current drive experiments using electron cyclotron current drive. As in many plasma discharges the electron temperature exceeds the ion temperature significantly, these plasmas are governed by core electron root confinement showing a strong positive electric field in the plasma centre.
Published: 2017

41. EULAR recommendations for cardiovascular disease risk management in patients with rheumatoid arthritis and other forms of inflammatory joint disorders : 2015/2016 update

Author: Agca, R., Heslinga, S. C., Rollefstad, S., Heslinga, M., McInnes, B., Peters, M. J. L., Kvien, T. K., Dougados, M., Radner, H., Atzeni, F., Primdahl, J., Södergren, Anna, Wållberg Jonsson, Solveig, van Rompay, J., Zabalan, C., Pedersen, T. R., Jacobsson, L., de Vlam, K., Gonzalez-Gay, M. A., Semb, A. G., Kitas, G. D., Smulders, Y. M., Szekanecz, Z., Sattar, N., Symmons, D. P. M., Nurmohamed, M. T., Agca, R., Heslinga, S. C., Rollefstad, S., Heslinga, M., McInnes, B., Peters, M. J. L., Kvien, T. K., Dougados, M., Radner, H., Atzeni, F., Primdahl, J., Södergren, Anna, Wållberg Jonsson, Solveig, van Rompay, J., Zabalan, C., Pedersen, T. R., Jacobsson, L., de Vlam, K., Gonzalez-Gay, M. A., Semb, A. G., Kitas, G. D., Smulders, Y. M., Szekanecz, Z., Sattar, N., Symmons, D. P. M., and Nurmohamed, M. T.
Abstract: Patients with rheumatoid arthritis (RA) and other inflammatory joint disorders (IJD) have increased cardiovascular disease (CVD) risk compared with the general population. In 2009, the European League Against Rheumatism (EULAR) taskforce recommended screening, identification of CVD risk factors and CVD risk management largely based on expert opinion. In view of substantial new evidence, an update was conducted with the aim of producing CVD risk management recommendations for patients with IJD that now incorporates an increasing evidence base. A multidisciplinary steering committee (representing 13 European countries) comprised 26 members including patient representatives, rheumatologists, cardiologists, internists, epidemiologists, a health professional and fellows. Systematic literature searches were performed and evidence was categorised according to standard guidelines. The evidence was discussed and summarised by the experts in the course of a consensus finding and voting process. Three overarching principles were defined. First, there is a higher risk for CVD in patients with RA, and this may also apply to ankylosing spondylitis and psoriatic arthritis. Second, the rheumatologist is responsible for CVD risk management in patients with IJD. Third, the use of non-steroidal anti-inflammatory drugs and corticosteroids should be in accordance with treatment-specific recommendations from EULAR and Assessment of Spondyloarthritis International Society. Ten recommendations were defined, of which one is new and six were changed compared with the 2009 recommendations. Each designated an appropriate evidence support level. The present update extends on the evidence that CVD risk in the whole spectrum of IJD is increased. This underscores the need for CVD risk management in these patients. These recommendations are defined to provide assistance in CVD risk management in IJD, based on expert opinion and scientific evidence.
Published: 2017
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42. Recovering missing values from corrupted spatio-temporal sensory data via robust low-rank tensor completion

Author: Candan, S., Chen, L., Pedersen, T., Chang, L., Hua, W., Ruan, Wenjie, Xu, Peipei, Sheng, Quan Z., Falkner, Nickolas J.G., Li, Xue, Zhang, Wei Emma, Candan, S., Chen, L., Pedersen, T., Chang, L., Hua, W., Ruan, Wenjie, Xu, Peipei, Sheng, Quan Z., Falkner, Nickolas J.G., Li, Xue, and Zhang, Wei Emma
Abstract: With the booming of the Internet of Things, tremendous amount of sensors have been installed in different geographic locations, generating massive sensory data with both time-stamps and geo-tags. Such type of data usually have shown complex spatio-temporal correlation and are easily missing in practice due to communication failure or data corruption. In this paper, we aim to tackle the challenge-how to accurately and efficiently recover the missing values for corrupted spatiotemporal sensory data. Specifically, we first formulate such sensor data as a high-dimensional tensor that can naturally preserve sensors’ both geographical and time information, thus we call spatio-temporal Tensor. Then we model the sensor data recovery as a low-rank robust tensor completion problem by exploiting its latent low-rank structure and sparse noise property. To solve this optimization problem, we design a highly efficient optimization method that combines the alternating direction method of multipliers and accelerated proximal gradient to minimize the tensor’s convex surrogate and noise’s ℓ1-norm. In addition to testing our method by a synthetic dataset, we also use passive RFID (radiofrequency identification) sensors to build a real-world sensor-array testbed, which generates overall 115,200 sensor readings for model evaluation. The experimental results demonstrate the accuracy and robustness of our approach.
Published: 2017

43. Marine-terminating glaciers sustain high productivity in Greenland fjords

Author: Meire, L., Mortensen, J., Meire, P., Juul-Pedersen, T., Sejr, M.K., Rysgaard, S., Nygaard, R., Huybrechts, P., Meysman, F.J.R., Meire, L., Mortensen, J., Meire, P., Juul-Pedersen, T., Sejr, M.K., Rysgaard, S., Nygaard, R., Huybrechts, P., and Meysman, F.J.R.
Abstract: Accelerated mass loss from the Greenland ice sheet leads to glacier retreat and an increasing input of glacial meltwater to the fjords and coastal waters around Greenland. These high latitude ecosystems are highly productive and sustain important fisheries, yet it remains uncertain how they will respond to future changes in the Arctic cryosphere. Here we show that marine‐terminating glaciers play a crucial role in sustaining high productivity of the fjord ecosystems. Hydrographic and biogeochemical data from two fjord systems adjacent to the Greenland ice sheet, suggest that marine ecosystem productivity is very differently regulated in fjords influenced by either land‐terminating or marine‐terminating glaciers. Rising subsurface meltwater plumes originating from marine‐terminating glaciers entrain large volumes of ambient deep water to the surface. The resulting upwelling of nutrient‐rich deep water sustains a high phytoplankton productivity throughout summer in the fjord with marine‐terminating glaciers. In contrast, the fjord with only land‐terminating glaciers lack this upwelling mechanism, and is characterized by lower productivity. Data on commercial halibut landings support that coastal regions influenced by large marine‐terminating glaciers have substantially higher marine productivity. These results suggest that a switch from marine‐terminating to land‐terminating glaciers can substantially alter the productivity in the coastal zone around Greenland with potentially large ecological and socio‐economic implications.
Published: 2017

44. Major results from the first plasma campaign of the Wendelstein 7-X stellarator

Author: Wolf, R.C., Ali, A., Alonso, A., Baldzuhn, J., Beidler, C., Beurskens, M., Biedermann, C., Bosch, H.S., Bozhenkov, S., Brakel, R., Dinklage, A., Feng, Y., Fuchert, G., Geiger, J., Grulke, O., Helander, P., Hirsch, M., Höfel, U., Jakubowski, M., Knauer, J., Kocsis, G., König, R., Kornejew, P., Kràmer-Flecken, A., Krychowiak, M., Landreman, M., Langenberg, A., Laqua, H. P., Lazerson, S., Maaßberg, H., Marsen, S., Marushchenko, M., Moseev, D., Niemann, H., Pablant, N., Pasch, E., Rahbarnia, K., Schlisio, G., Stange, T., Sunn Pedersen, T., Svensson, J., Szepesi, T., Trimino Mora, H., Turkin, Y., Wauters, T., Weir, G., Wenzel, U., Windisch, T., Wurden, G., Zhang, D., Abramovic, I., Äkàslompolo, S., Aleynikov, P., Aleynikova, K., Alzbutas, R., Anda, G., Andreeva, T., Ascasibar, E., Assmann, J., Baek, S. G., Banduch, M., Barbui, T., Barlak, M., Baumann, K., Behr, W., Benndorf, A., Bertuch, O., Biel, W., Birus, D., Blackwell, B., Blanco, E., Blatzheim, M., Bluhm, T., Böckenhoff, D., Bolgert, P., Borchardt, M., Borsuk, V., Boscary, J., Böttger, L. G., Brand, H., Brandt, Ch, Bràuer, T., Braune, H., Brezinsek, S., Brunner, K. J., Brünner, B., Burhenn, R., Buttenschön, B., Bykov, V., Calvo, I., Cannas, B., Cappa, A., Carls, A., Carraro, L., Carvalho, B., Castejon, F., Charl, A., Chernyshev, F., Cianciosa, M., Citarella, R., Ciupiński, Claps, G., Cole, M., Cole, M. J., Cordella, F., Cseh, G., Czarnecka, A., Czermak, A., Czerski, K., Czerwinski, M., Czymek, G., Da Molin, A., Da Silva, A., Dammertz, G., Danielson, J., De La Pena, A., Degenkolbe, S., Denner, P., Dhard, D. P., Dostal, M., Drevlak, M., Drewelow, P., Drews, Ph, Dudek, A., Dundulis, G., Durodie, F., Van Eeten, P., Effenberg, F., Ehrke, G., Endler, M., Ennis, D., Erckmann, E., Esteban, H., Estrada, T., Fahrenkamp, N., Feist, J. H., Fellinger, J., Fernandes, H., Fietz, W. H., Figacz, W., Fontdecaba, J., Ford, O., Fornal, T., Frerichs, H., Freund, A., Führer, M., Funaba, T., Galkowski, A., Gantenbein, G., Gao, Y., García Regaña, J., Garcia-Munoz, M., Gates, D., Gawlik, G., Geiger, B., Giannella, V., Gierse, N., Gogoleva, A., Goncalves, B., Goriaev, A., Gradic, D., Grahl, M., Green, J., Grosman, A., Grote, H., Gruca, M., Guerard, C., Haiduk, L., Han, X., Harberts, F., Harris, J. H., Hartfuß, H. J., Hartmann, D., Hathiramani, D., Hein, B., Heinemann, B., Heitzenroeder, P., Henneberg, S., Hennig, C., Hernandez Sanchez, J., Hidalgo, C., Hölbe, H., Hollfeld, K. P., Hölting, A., Höschen, D., Houry, M., Howard, J., Huang, X., Huber, M., Huber, V., Hunger, H., Ida, K., Ilkei, T., Illy, S., Israeli, B., Ivanov, A., Jablonski, S., Jagielski, J., Jelonnek, J., Jenzsch, H., Junghans, P., Kacmarczyk, J., Kaliatka, T., Kallmeyer, J. P., Kamionka, U., Karalevicius, R., Kasahara, H., Kasparek, W., Kenmochi, N., Keunecke, M., Khilchenko, A., Kinna, D., Kleiber, R., Klinger, T., Knaup, M., Kobarg, Th, Köchl, F., Kolesnichenko, Y., Könies, A., Köppen, M., Koshurinov, J., Koslowski, R., Köster, F., Koziol, R., Krämer, M., Krampitz, R., Kraszewsk, P., Krawczyk, N., Kremeyer, T., Krings, Th, Krom, J., Krzesinski, G., Ksiazek, I., Kubkowska, M., Kühner, G., Kurki-Suonio, T., Kwak, S., Lang, R., Langish, S., Laube, R., Lechte, C., Lennartz, M., Leonhardt, W., Lewerentz, L., Liang, Y., Linsmeier, Ch, Liu, S., Lobsien, J. F., Loesser, D., Loizu Cisquella, J., Lore, J., Lorenz, A., Losert, M., Lubyako, L., Lücke, A., Lumsdaine, A., Lutsenko, V., Majano-Brown, J., Marchuk, O., Mardenfeld, M., Marek, P., Massidda, S., Masuzaki, S., Maurer, D., McCarthy, K., McNeely, P., Meier, A., Mellein, D., Mendelevitch, B., Mertens, Ph, Mikkelsen, D., Mishchenko, O., Missal, B., Mittelstaedt, J., Mizuuchi, T., Mollen, A., Moncada, V., Mönnich, T., Morizaki, T., Munk, R., Murakami, S., Musielok, F., Náfrádi, G., Nagel, M., Naujoks, D., Neilson, H., Neubauer, O., Neuner, U., Ngo, T., Nocentini, R., Nührenberg, C., Nührenberg, J., Obermayer, S., Offermanns, G., Ogawa, K., Ongena, J., Oosterbeek, J. W., Orozco, G., Otte, M., Pacios Rodriguez, L., Pan, W., Panadero, N., Panadero Alvarez, N., Panin, A., Papenfuß, D., Paqay, S., Pavone, A., Pawelec, E., Pelka, G., Peng, X., Perseo, V., Peterson, B., Pieper, A., Pilopp, D., Pingel, S., Pisano, F., Plaum, B., Plunk, G., Povilaitis, M., Preinhaelter, J., Proll, J., Puiatti, M. E., Puig Sitjes, A., Purps, F., Rack, M., Récsei, S., Reiman, A., Reiter, D., Remppel, F., Renard, S., Riedl, R., Riemann, J., Rimkevicius, S., Riße, K., Rodatos, A., Röhlinger, H., Romé, M., Rong, P., Roscher, H. J., Roth, B., Rudischhauser, L., Rummel, K., Rummel, T., Runov, A., Rust, N., Ryc, L., Ryosuke, S., Sakamoto, R., Samartsev, A., Sanchez, M., Sano, F., Satake, S., Satheeswaran, G., Schacht, J., Schauer, F., Scherer, T., Schlaich, A., Schlüter, K. H., Schmitt, J., Schmitz, H., Schmitz, O., Schmuck, S., Schneider, M., Schneider, W., Scholz, M., Scholz, P., Schrittwieser, R., Schröder, M., Schröder, T., Schroeder, R., Schumacher, H., Schweer, B., Shanahan, B., Shikhovtsev, I. V., Sibilia, M., Sinha, P., Siplià, S., Skodzik, J., Slaby, C., Smith, H., Spiess, W., Spong, D. A., Spring, A., Stadler, R., Standley, B., Stephey, L., Stoneking, M., Stridde, U., Sulek, Z., Surko, C., Suzuki, Y., Szabó, V., Szabolics, T., Szökefalvi-Nagy, Z., Tamura, N., Terra, A., Terry, J., Thomas, J., Thomsen, H., Thumm, M., Von Thun, C. P., Timmermann, D., Titus, P., Toi, K., Travere, J. M., Traverso, P., Tretter, J., Tsuchiya, H., Tsujimura, T., Tulipán, S., Turnyanskiy, M., Unterberg, B., Urban, J., Urbonavicius, E., Vakulchyk, I., Valet, S., Van Millingen, B., Vela, L., Velasco, J. L., Vergote, M., Vervier, M., Vianello, N., Viebke, H., Vilbrandt, R., Vorkörper, A., Wadle, S., Wagner, F., Wang, E., Wang, N., Warmer, F., Wegener, L., Weggen, J., Wei, Y., Wendorf, J., Werner, A., Wiegel, B., Wilde, F., Winkler, E., Winters, V., Wolf, S., Wolowski, J., Wright, A., Xanthopoulos, P., Yamada, H., Yamada, I., Yasuhara, R., Yokoyama, M., Zajac, J., Zarnstorff, M., Zeitler, A., Zhang, H., Zhu, J., Zilker, M., Zimbal, A., Zocco, A., Zoletnik, S., Zuin, M., Wolf, R.C., Ali, A., Alonso, A., Baldzuhn, J., Beidler, C., Beurskens, M., Biedermann, C., Bosch, H.S., Bozhenkov, S., Brakel, R., Dinklage, A., Feng, Y., Fuchert, G., Geiger, J., Grulke, O., Helander, P., Hirsch, M., Höfel, U., Jakubowski, M., Knauer, J., Kocsis, G., König, R., Kornejew, P., Kràmer-Flecken, A., Krychowiak, M., Landreman, M., Langenberg, A., Laqua, H. P., Lazerson, S., Maaßberg, H., Marsen, S., Marushchenko, M., Moseev, D., Niemann, H., Pablant, N., Pasch, E., Rahbarnia, K., Schlisio, G., Stange, T., Sunn Pedersen, T., Svensson, J., Szepesi, T., Trimino Mora, H., Turkin, Y., Wauters, T., Weir, G., Wenzel, U., Windisch, T., Wurden, G., Zhang, D., Abramovic, I., Äkàslompolo, S., Aleynikov, P., Aleynikova, K., Alzbutas, R., Anda, G., Andreeva, T., Ascasibar, E., Assmann, J., Baek, S. G., Banduch, M., Barbui, T., Barlak, M., Baumann, K., Behr, W., Benndorf, A., Bertuch, O., Biel, W., Birus, D., Blackwell, B., Blanco, E., Blatzheim, M., Bluhm, T., Böckenhoff, D., Bolgert, P., Borchardt, M., Borsuk, V., Boscary, J., Böttger, L. G., Brand, H., Brandt, Ch, Bràuer, T., Braune, H., Brezinsek, S., Brunner, K. J., Brünner, B., Burhenn, R., Buttenschön, B., Bykov, V., Calvo, I., Cannas, B., Cappa, A., Carls, A., Carraro, L., Carvalho, B., Castejon, F., Charl, A., Chernyshev, F., Cianciosa, M., Citarella, R., Ciupiński, Claps, G., Cole, M., Cole, M. J., Cordella, F., Cseh, G., Czarnecka, A., Czermak, A., Czerski, K., Czerwinski, M., Czymek, G., Da Molin, A., Da Silva, A., Dammertz, G., Danielson, J., De La Pena, A., Degenkolbe, S., Denner, P., Dhard, D. P., Dostal, M., Drevlak, M., Drewelow, P., Drews, Ph, Dudek, A., Dundulis, G., Durodie, F., Van Eeten, P., Effenberg, F., Ehrke, G., Endler, M., Ennis, D., Erckmann, E., Esteban, H., Estrada, T., Fahrenkamp, N., Feist, J. H., Fellinger, J., Fernandes, H., Fietz, W. H., Figacz, W., Fontdecaba, J., Ford, O., Fornal, T., Frerichs, H., Freund, A., Führer, M., Funaba, T., Galkowski, A., Gantenbein, G., Gao, Y., García Regaña, J., Garcia-Munoz, M., Gates, D., Gawlik, G., Geiger, B., Giannella, V., Gierse, N., Gogoleva, A., Goncalves, B., Goriaev, A., Gradic, D., Grahl, M., Green, J., Grosman, A., Grote, H., Gruca, M., Guerard, C., Haiduk, L., Han, X., Harberts, F., Harris, J. H., Hartfuß, H. J., Hartmann, D., Hathiramani, D., Hein, B., Heinemann, B., Heitzenroeder, P., Henneberg, S., Hennig, C., Hernandez Sanchez, J., Hidalgo, C., Hölbe, H., Hollfeld, K. P., Hölting, A., Höschen, D., Houry, M., Howard, J., Huang, X., Huber, M., Huber, V., Hunger, H., Ida, K., Ilkei, T., Illy, S., Israeli, B., Ivanov, A., Jablonski, S., Jagielski, J., Jelonnek, J., Jenzsch, H., Junghans, P., Kacmarczyk, J., Kaliatka, T., Kallmeyer, J. P., Kamionka, U., Karalevicius, R., Kasahara, H., Kasparek, W., Kenmochi, N., Keunecke, M., Khilchenko, A., Kinna, D., Kleiber, R., Klinger, T., Knaup, M., Kobarg, Th, Köchl, F., Kolesnichenko, Y., Könies, A., Köppen, M., Koshurinov, J., Koslowski, R., Köster, F., Koziol, R., Krämer, M., Krampitz, R., Kraszewsk, P., Krawczyk, N., Kremeyer, T., Krings, Th, Krom, J., Krzesinski, G., Ksiazek, I., Kubkowska, M., Kühner, G., Kurki-Suonio, T., Kwak, S., Lang, R., Langish, S., Laube, R., Lechte, C., Lennartz, M., Leonhardt, W., Lewerentz, L., Liang, Y., Linsmeier, Ch, Liu, S., Lobsien, J. F., Loesser, D., Loizu Cisquella, J., Lore, J., Lorenz, A., Losert, M., Lubyako, L., Lücke, A., Lumsdaine, A., Lutsenko, V., Majano-Brown, J., Marchuk, O., Mardenfeld, M., Marek, P., Massidda, S., Masuzaki, S., Maurer, D., McCarthy, K., McNeely, P., Meier, A., Mellein, D., Mendelevitch, B., Mertens, Ph, Mikkelsen, D., Mishchenko, O., Missal, B., Mittelstaedt, J., Mizuuchi, T., Mollen, A., Moncada, V., Mönnich, T., Morizaki, T., Munk, R., Murakami, S., Musielok, F., Náfrádi, G., Nagel, M., Naujoks, D., Neilson, H., Neubauer, O., Neuner, U., Ngo, T., Nocentini, R., Nührenberg, C., Nührenberg, J., Obermayer, S., Offermanns, G., Ogawa, K., Ongena, J., Oosterbeek, J. W., Orozco, G., Otte, M., Pacios Rodriguez, L., Pan, W., Panadero, N., Panadero Alvarez, N., Panin, A., Papenfuß, D., Paqay, S., Pavone, A., Pawelec, E., Pelka, G., Peng, X., Perseo, V., Peterson, B., Pieper, A., Pilopp, D., Pingel, S., Pisano, F., Plaum, B., Plunk, G., Povilaitis, M., Preinhaelter, J., Proll, J., Puiatti, M. E., Puig Sitjes, A., Purps, F., Rack, M., Récsei, S., Reiman, A., Reiter, D., Remppel, F., Renard, S., Riedl, R., Riemann, J., Rimkevicius, S., Riße, K., Rodatos, A., Röhlinger, H., Romé, M., Rong, P., Roscher, H. J., Roth, B., Rudischhauser, L., Rummel, K., Rummel, T., Runov, A., Rust, N., Ryc, L., Ryosuke, S., Sakamoto, R., Samartsev, A., Sanchez, M., Sano, F., Satake, S., Satheeswaran, G., Schacht, J., Schauer, F., Scherer, T., Schlaich, A., Schlüter, K. H., Schmitt, J., Schmitz, H., Schmitz, O., Schmuck, S., Schneider, M., Schneider, W., Scholz, M., Scholz, P., Schrittwieser, R., Schröder, M., Schröder, T., Schroeder, R., Schumacher, H., Schweer, B., Shanahan, B., Shikhovtsev, I. V., Sibilia, M., Sinha, P., Siplià, S., Skodzik, J., Slaby, C., Smith, H., Spiess, W., Spong, D. A., Spring, A., Stadler, R., Standley, B., Stephey, L., Stoneking, M., Stridde, U., Sulek, Z., Surko, C., Suzuki, Y., Szabó, V., Szabolics, T., Szökefalvi-Nagy, Z., Tamura, N., Terra, A., Terry, J., Thomas, J., Thomsen, H., Thumm, M., Von Thun, C. P., Timmermann, D., Titus, P., Toi, K., Travere, J. M., Traverso, P., Tretter, J., Tsuchiya, H., Tsujimura, T., Tulipán, S., Turnyanskiy, M., Unterberg, B., Urban, J., Urbonavicius, E., Vakulchyk, I., Valet, S., Van Millingen, B., Vela, L., Velasco, J. L., Vergote, M., Vervier, M., Vianello, N., Viebke, H., Vilbrandt, R., Vorkörper, A., Wadle, S., Wagner, F., Wang, E., Wang, N., Warmer, F., Wegener, L., Weggen, J., Wei, Y., Wendorf, J., Werner, A., Wiegel, B., Wilde, F., Winkler, E., Winters, V., Wolf, S., Wolowski, J., Wright, A., Xanthopoulos, P., Yamada, H., Yamada, I., Yasuhara, R., Yokoyama, M., Zajac, J., Zarnstorff, M., Zeitler, A., Zhang, H., Zhu, J., Zilker, M., Zimbal, A., Zocco, A., Zoletnik, S., and Zuin, M.
Abstract: After completing the main construction phase of Wendelstein 7-X (W7-X) and successfully commissioning the device, first plasma operation started at the end of 2015. Integral commissioning of plasma start-up and operation using electron cyclotron resonance heating (ECRH) and an extensive set of plasma diagnostics have been completed, allowing initial physics studies during the first operational campaign. Both in helium and hydrogen, plasma breakdown was easily achieved. Gaining experience with plasma vessel conditioning, discharge lengths could be extended gradually. Eventually, discharges lasted up to 6 s, reaching an injected energy of 4 MJ, which is twice the limit originally agreed for the limiter configuration employed during the first operational campaign. At power levels of 4 MW central electron densities reached 3 1019 m-3, central electron temperatures reached values of 7 keV and ion temperatures reached just above 2 keV. Important physics studies during this first operational phase include a first assessment of power balance and energy confinement, ECRH power deposition experiments, 2nd harmonic O-mode ECRH using multi-pass absorption, and current drive experiments using electron cyclotron current drive. As in many plasma discharges the electron temperature exceeds the ion temperature significantly, these plasmas are governed by core electron root confinement showing a strong positive electric field in the plasma centre.
Published: 2017

45. Marine-terminating glaciers sustain high productivity in Greenland fjords

Author: Meire, L., Mortensen, J., Meire, P., Juul-Pedersen, T., Sejr, M.K., Rysgaard, S., Nygaard, R., Huybrechts, P., Meysman, F.J.R., Meire, L., Mortensen, J., Meire, P., Juul-Pedersen, T., Sejr, M.K., Rysgaard, S., Nygaard, R., Huybrechts, P., and Meysman, F.J.R.
Abstract: Accelerated mass loss from the Greenland ice sheet leads to glacier retreat and an increasing input of glacial meltwater to the fjords and coastal waters around Greenland. These high latitude ecosystems are highly productive and sustain important fisheries, yet it remains uncertain how they will respond to future changes in the Arctic cryosphere. Here we show that marine‐terminating glaciers play a crucial role in sustaining high productivity of the fjord ecosystems. Hydrographic and biogeochemical data from two fjord systems adjacent to the Greenland ice sheet, suggest that marine ecosystem productivity is very differently regulated in fjords influenced by either land‐terminating or marine‐terminating glaciers. Rising subsurface meltwater plumes originating from marine‐terminating glaciers entrain large volumes of ambient deep water to the surface. The resulting upwelling of nutrient‐rich deep water sustains a high phytoplankton productivity throughout summer in the fjord with marine‐terminating glaciers. In contrast, the fjord with only land‐terminating glaciers lack this upwelling mechanism, and is characterized by lower productivity. Data on commercial halibut landings support that coastal regions influenced by large marine‐terminating glaciers have substantially higher marine productivity. These results suggest that a switch from marine‐terminating to land‐terminating glaciers can substantially alter the productivity in the coastal zone around Greenland with potentially large ecological and socio‐economic implications.
Published: 2017

46. Recovering missing values from corrupted spatio-temporal sensory data via robust low-rank tensor completion

Author: Candan, S., Chen, L., Pedersen, T., Chang, L., Hua, W., Ruan, Wenjie, Xu, Peipei, Sheng, Quan Z., Falkner, Nickolas J.G., Li, Xue, Zhang, Wei Emma, Candan, S., Chen, L., Pedersen, T., Chang, L., Hua, W., Ruan, Wenjie, Xu, Peipei, Sheng, Quan Z., Falkner, Nickolas J.G., Li, Xue, and Zhang, Wei Emma
Abstract: With the booming of the Internet of Things, tremendous amount of sensors have been installed in different geographic locations, generating massive sensory data with both time-stamps and geo-tags. Such type of data usually have shown complex spatio-temporal correlation and are easily missing in practice due to communication failure or data corruption. In this paper, we aim to tackle the challenge-how to accurately and efficiently recover the missing values for corrupted spatiotemporal sensory data. Specifically, we first formulate such sensor data as a high-dimensional tensor that can naturally preserve sensors’ both geographical and time information, thus we call spatio-temporal Tensor. Then we model the sensor data recovery as a low-rank robust tensor completion problem by exploiting its latent low-rank structure and sparse noise property. To solve this optimization problem, we design a highly efficient optimization method that combines the alternating direction method of multipliers and accelerated proximal gradient to minimize the tensor’s convex surrogate and noise’s ℓ1-norm. In addition to testing our method by a synthetic dataset, we also use passive RFID (radiofrequency identification) sensors to build a real-world sensor-array testbed, which generates overall 115,200 sensor readings for model evaluation. The experimental results demonstrate the accuracy and robustness of our approach.
Published: 2017

47. Major results from the first plasma campaign of the Wendelstein 7-X stellarator

Author: Wolf, R.C., Ali, A., Alonso, A., Baldzuhn, J., Beidler, C., Beurskens, M., Biedermann, C., Bosch, H.S., Bozhenkov, S., Brakel, R., Dinklage, A., Feng, Y., Fuchert, G., Geiger, J., Grulke, O., Helander, P., Hirsch, M., Höfel, U., Jakubowski, M., Knauer, J., Kocsis, G., König, R., Kornejew, P., Kràmer-Flecken, A., Krychowiak, M., Landreman, M., Langenberg, A., Laqua, H. P., Lazerson, S., Maaßberg, H., Marsen, S., Marushchenko, M., Moseev, D., Niemann, H., Pablant, N., Pasch, E., Rahbarnia, K., Schlisio, G., Stange, T., Sunn Pedersen, T., Svensson, J., Szepesi, T., Trimino Mora, H., Turkin, Y., Wauters, T., Weir, G., Wenzel, U., Windisch, T., Wurden, G., Zhang, D., Abramovic, I., Äkàslompolo, S., Aleynikov, P., Aleynikova, K., Alzbutas, R., Anda, G., Andreeva, T., Ascasibar, E., Assmann, J., Baek, S. G., Banduch, M., Barbui, T., Barlak, M., Baumann, K., Behr, W., Benndorf, A., Bertuch, O., Biel, W., Birus, D., Blackwell, B., Blanco, E., Blatzheim, M., Bluhm, T., Böckenhoff, D., Bolgert, P., Borchardt, M., Borsuk, V., Boscary, J., Böttger, L. G., Brand, H., Brandt, Ch, Bràuer, T., Braune, H., Brezinsek, S., Brunner, K. J., Brünner, B., Burhenn, R., Buttenschön, B., Bykov, V., Calvo, I., Cannas, B., Cappa, A., Carls, A., Carraro, L., Carvalho, B., Castejon, F., Charl, A., Chernyshev, F., Cianciosa, M., Citarella, R., Ciupiński, Claps, G., Cole, M., Cole, M. J., Cordella, F., Cseh, G., Czarnecka, A., Czermak, A., Czerski, K., Czerwinski, M., Czymek, G., Da Molin, A., Da Silva, A., Dammertz, G., Danielson, J., De La Pena, A., Degenkolbe, S., Denner, P., Dhard, D. P., Dostal, M., Drevlak, M., Drewelow, P., Drews, Ph, Dudek, A., Dundulis, G., Durodie, F., Van Eeten, P., Effenberg, F., Ehrke, G., Endler, M., Ennis, D., Erckmann, E., Esteban, H., Estrada, T., Fahrenkamp, N., Feist, J. H., Fellinger, J., Fernandes, H., Fietz, W. H., Figacz, W., Fontdecaba, J., Ford, O., Fornal, T., Frerichs, H., Freund, A., Führer, M., Funaba, T., Galkowski, A., Gantenbein, G., Gao, Y., García Regaña, J., Garcia-Munoz, M., Gates, D., Gawlik, G., Geiger, B., Giannella, V., Gierse, N., Gogoleva, A., Goncalves, B., Goriaev, A., Gradic, D., Grahl, M., Green, J., Grosman, A., Grote, H., Gruca, M., Guerard, C., Haiduk, L., Han, X., Harberts, F., Harris, J. H., Hartfuß, H. J., Hartmann, D., Hathiramani, D., Hein, B., Heinemann, B., Heitzenroeder, P., Henneberg, S., Hennig, C., Hernandez Sanchez, J., Hidalgo, C., Hölbe, H., Hollfeld, K. P., Hölting, A., Höschen, D., Houry, M., Howard, J., Huang, X., Huber, M., Huber, V., Hunger, H., Ida, K., Ilkei, T., Illy, S., Israeli, B., Ivanov, A., Jablonski, S., Jagielski, J., Jelonnek, J., Jenzsch, H., Junghans, P., Kacmarczyk, J., Kaliatka, T., Kallmeyer, J. P., Kamionka, U., Karalevicius, R., Kasahara, H., Kasparek, W., Kenmochi, N., Keunecke, M., Khilchenko, A., Kinna, D., Kleiber, R., Klinger, T., Knaup, M., Kobarg, Th, Köchl, F., Kolesnichenko, Y., Könies, A., Köppen, M., Koshurinov, J., Koslowski, R., Köster, F., Koziol, R., Krämer, M., Krampitz, R., Kraszewsk, P., Krawczyk, N., Kremeyer, T., Krings, Th, Krom, J., Krzesinski, G., Ksiazek, I., Kubkowska, M., Kühner, G., Kurki-Suonio, T., Kwak, S., Lang, R., Langish, S., Laube, R., Lechte, C., Lennartz, M., Leonhardt, W., Lewerentz, L., Liang, Y., Linsmeier, Ch, Liu, S., Lobsien, J. F., Loesser, D., Loizu Cisquella, J., Lore, J., Lorenz, A., Losert, M., Lubyako, L., Lücke, A., Lumsdaine, A., Lutsenko, V., Majano-Brown, J., Marchuk, O., Mardenfeld, M., Marek, P., Massidda, S., Masuzaki, S., Maurer, D., McCarthy, K., McNeely, P., Meier, A., Mellein, D., Mendelevitch, B., Mertens, Ph, Mikkelsen, D., Mishchenko, O., Missal, B., Mittelstaedt, J., Mizuuchi, T., Mollen, A., Moncada, V., Mönnich, T., Morizaki, T., Munk, R., Murakami, S., Musielok, F., Náfrádi, G., Nagel, M., Naujoks, D., Neilson, H., Neubauer, O., Neuner, U., Ngo, T., Nocentini, R., Nührenberg, C., Nührenberg, J., Obermayer, S., Offermanns, G., Ogawa, K., Ongena, J., Oosterbeek, J. W., Orozco, G., Otte, M., Pacios Rodriguez, L., Pan, W., Panadero, N., Panadero Alvarez, N., Panin, A., Papenfuß, D., Paqay, S., Pavone, A., Pawelec, E., Pelka, G., Peng, X., Perseo, V., Peterson, B., Pieper, A., Pilopp, D., Pingel, S., Pisano, F., Plaum, B., Plunk, G., Povilaitis, M., Preinhaelter, J., Proll, J., Puiatti, M. E., Puig Sitjes, A., Purps, F., Rack, M., Récsei, S., Reiman, A., Reiter, D., Remppel, F., Renard, S., Riedl, R., Riemann, J., Rimkevicius, S., Riße, K., Rodatos, A., Röhlinger, H., Romé, M., Rong, P., Roscher, H. J., Roth, B., Rudischhauser, L., Rummel, K., Rummel, T., Runov, A., Rust, N., Ryc, L., Ryosuke, S., Sakamoto, R., Samartsev, A., Sanchez, M., Sano, F., Satake, S., Satheeswaran, G., Schacht, J., Schauer, F., Scherer, T., Schlaich, A., Schlüter, K. H., Schmitt, J., Schmitz, H., Schmitz, O., Schmuck, S., Schneider, M., Schneider, W., Scholz, M., Scholz, P., Schrittwieser, R., Schröder, M., Schröder, T., Schroeder, R., Schumacher, H., Schweer, B., Shanahan, B., Shikhovtsev, I. V., Sibilia, M., Sinha, P., Siplià, S., Skodzik, J., Slaby, C., Smith, H., Spiess, W., Spong, D. A., Spring, A., Stadler, R., Standley, B., Stephey, L., Stoneking, M., Stridde, U., Sulek, Z., Surko, C., Suzuki, Y., Szabó, V., Szabolics, T., Szökefalvi-Nagy, Z., Tamura, N., Terra, A., Terry, J., Thomas, J., Thomsen, H., Thumm, M., Von Thun, C. P., Timmermann, D., Titus, P., Toi, K., Travere, J. M., Traverso, P., Tretter, J., Tsuchiya, H., Tsujimura, T., Tulipán, S., Turnyanskiy, M., Unterberg, B., Urban, J., Urbonavicius, E., Vakulchyk, I., Valet, S., Van Millingen, B., Vela, L., Velasco, J. L., Vergote, M., Vervier, M., Vianello, N., Viebke, H., Vilbrandt, R., Vorkörper, A., Wadle, S., Wagner, F., Wang, E., Wang, N., Warmer, F., Wegener, L., Weggen, J., Wei, Y., Wendorf, J., Werner, A., Wiegel, B., Wilde, F., Winkler, E., Winters, V., Wolf, S., Wolowski, J., Wright, A., Xanthopoulos, P., Yamada, H., Yamada, I., Yasuhara, R., Yokoyama, M., Zajac, J., Zarnstorff, M., Zeitler, A., Zhang, H., Zhu, J., Zilker, M., Zimbal, A., Zocco, A., Zoletnik, S., Zuin, M., Wolf, R.C., Ali, A., Alonso, A., Baldzuhn, J., Beidler, C., Beurskens, M., Biedermann, C., Bosch, H.S., Bozhenkov, S., Brakel, R., Dinklage, A., Feng, Y., Fuchert, G., Geiger, J., Grulke, O., Helander, P., Hirsch, M., Höfel, U., Jakubowski, M., Knauer, J., Kocsis, G., König, R., Kornejew, P., Kràmer-Flecken, A., Krychowiak, M., Landreman, M., Langenberg, A., Laqua, H. P., Lazerson, S., Maaßberg, H., Marsen, S., Marushchenko, M., Moseev, D., Niemann, H., Pablant, N., Pasch, E., Rahbarnia, K., Schlisio, G., Stange, T., Sunn Pedersen, T., Svensson, J., Szepesi, T., Trimino Mora, H., Turkin, Y., Wauters, T., Weir, G., Wenzel, U., Windisch, T., Wurden, G., Zhang, D., Abramovic, I., Äkàslompolo, S., Aleynikov, P., Aleynikova, K., Alzbutas, R., Anda, G., Andreeva, T., Ascasibar, E., Assmann, J., Baek, S. G., Banduch, M., Barbui, T., Barlak, M., Baumann, K., Behr, W., Benndorf, A., Bertuch, O., Biel, W., Birus, D., Blackwell, B., Blanco, E., Blatzheim, M., Bluhm, T., Böckenhoff, D., Bolgert, P., Borchardt, M., Borsuk, V., Boscary, J., Böttger, L. G., Brand, H., Brandt, Ch, Bràuer, T., Braune, H., Brezinsek, S., Brunner, K. J., Brünner, B., Burhenn, R., Buttenschön, B., Bykov, V., Calvo, I., Cannas, B., Cappa, A., Carls, A., Carraro, L., Carvalho, B., Castejon, F., Charl, A., Chernyshev, F., Cianciosa, M., Citarella, R., Ciupiński, Claps, G., Cole, M., Cole, M. J., Cordella, F., Cseh, G., Czarnecka, A., Czermak, A., Czerski, K., Czerwinski, M., Czymek, G., Da Molin, A., Da Silva, A., Dammertz, G., Danielson, J., De La Pena, A., Degenkolbe, S., Denner, P., Dhard, D. P., Dostal, M., Drevlak, M., Drewelow, P., Drews, Ph, Dudek, A., Dundulis, G., Durodie, F., Van Eeten, P., Effenberg, F., Ehrke, G., Endler, M., Ennis, D., Erckmann, E., Esteban, H., Estrada, T., Fahrenkamp, N., Feist, J. H., Fellinger, J., Fernandes, H., Fietz, W. H., Figacz, W., Fontdecaba, J., Ford, O., Fornal, T., Frerichs, H., Freund, A., Führer, M., Funaba, T., Galkowski, A., Gantenbein, G., Gao, Y., García Regaña, J., Garcia-Munoz, M., Gates, D., Gawlik, G., Geiger, B., Giannella, V., Gierse, N., Gogoleva, A., Goncalves, B., Goriaev, A., Gradic, D., Grahl, M., Green, J., Grosman, A., Grote, H., Gruca, M., Guerard, C., Haiduk, L., Han, X., Harberts, F., Harris, J. H., Hartfuß, H. J., Hartmann, D., Hathiramani, D., Hein, B., Heinemann, B., Heitzenroeder, P., Henneberg, S., Hennig, C., Hernandez Sanchez, J., Hidalgo, C., Hölbe, H., Hollfeld, K. P., Hölting, A., Höschen, D., Houry, M., Howard, J., Huang, X., Huber, M., Huber, V., Hunger, H., Ida, K., Ilkei, T., Illy, S., Israeli, B., Ivanov, A., Jablonski, S., Jagielski, J., Jelonnek, J., Jenzsch, H., Junghans, P., Kacmarczyk, J., Kaliatka, T., Kallmeyer, J. P., Kamionka, U., Karalevicius, R., Kasahara, H., Kasparek, W., Kenmochi, N., Keunecke, M., Khilchenko, A., Kinna, D., Kleiber, R., Klinger, T., Knaup, M., Kobarg, Th, Köchl, F., Kolesnichenko, Y., Könies, A., Köppen, M., Koshurinov, J., Koslowski, R., Köster, F., Koziol, R., Krämer, M., Krampitz, R., Kraszewsk, P., Krawczyk, N., Kremeyer, T., Krings, Th, Krom, J., Krzesinski, G., Ksiazek, I., Kubkowska, M., Kühner, G., Kurki-Suonio, T., Kwak, S., Lang, R., Langish, S., Laube, R., Lechte, C., Lennartz, M., Leonhardt, W., Lewerentz, L., Liang, Y., Linsmeier, Ch, Liu, S., Lobsien, J. F., Loesser, D., Loizu Cisquella, J., Lore, J., Lorenz, A., Losert, M., Lubyako, L., Lücke, A., Lumsdaine, A., Lutsenko, V., Majano-Brown, J., Marchuk, O., Mardenfeld, M., Marek, P., Massidda, S., Masuzaki, S., Maurer, D., McCarthy, K., McNeely, P., Meier, A., Mellein, D., Mendelevitch, B., Mertens, Ph, Mikkelsen, D., Mishchenko, O., Missal, B., Mittelstaedt, J., Mizuuchi, T., Mollen, A., Moncada, V., Mönnich, T., Morizaki, T., Munk, R., Murakami, S., Musielok, F., Náfrádi, G., Nagel, M., Naujoks, D., Neilson, H., Neubauer, O., Neuner, U., Ngo, T., Nocentini, R., Nührenberg, C., Nührenberg, J., Obermayer, S., Offermanns, G., Ogawa, K., Ongena, J., Oosterbeek, J. W., Orozco, G., Otte, M., Pacios Rodriguez, L., Pan, W., Panadero, N., Panadero Alvarez, N., Panin, A., Papenfuß, D., Paqay, S., Pavone, A., Pawelec, E., Pelka, G., Peng, X., Perseo, V., Peterson, B., Pieper, A., Pilopp, D., Pingel, S., Pisano, F., Plaum, B., Plunk, G., Povilaitis, M., Preinhaelter, J., Proll, J., Puiatti, M. E., Puig Sitjes, A., Purps, F., Rack, M., Récsei, S., Reiman, A., Reiter, D., Remppel, F., Renard, S., Riedl, R., Riemann, J., Rimkevicius, S., Riße, K., Rodatos, A., Röhlinger, H., Romé, M., Rong, P., Roscher, H. J., Roth, B., Rudischhauser, L., Rummel, K., Rummel, T., Runov, A., Rust, N., Ryc, L., Ryosuke, S., Sakamoto, R., Samartsev, A., Sanchez, M., Sano, F., Satake, S., Satheeswaran, G., Schacht, J., Schauer, F., Scherer, T., Schlaich, A., Schlüter, K. H., Schmitt, J., Schmitz, H., Schmitz, O., Schmuck, S., Schneider, M., Schneider, W., Scholz, M., Scholz, P., Schrittwieser, R., Schröder, M., Schröder, T., Schroeder, R., Schumacher, H., Schweer, B., Shanahan, B., Shikhovtsev, I. V., Sibilia, M., Sinha, P., Siplià, S., Skodzik, J., Slaby, C., Smith, H., Spiess, W., Spong, D. A., Spring, A., Stadler, R., Standley, B., Stephey, L., Stoneking, M., Stridde, U., Sulek, Z., Surko, C., Suzuki, Y., Szabó, V., Szabolics, T., Szökefalvi-Nagy, Z., Tamura, N., Terra, A., Terry, J., Thomas, J., Thomsen, H., Thumm, M., Von Thun, C. P., Timmermann, D., Titus, P., Toi, K., Travere, J. M., Traverso, P., Tretter, J., Tsuchiya, H., Tsujimura, T., Tulipán, S., Turnyanskiy, M., Unterberg, B., Urban, J., Urbonavicius, E., Vakulchyk, I., Valet, S., Van Millingen, B., Vela, L., Velasco, J. L., Vergote, M., Vervier, M., Vianello, N., Viebke, H., Vilbrandt, R., Vorkörper, A., Wadle, S., Wagner, F., Wang, E., Wang, N., Warmer, F., Wegener, L., Weggen, J., Wei, Y., Wendorf, J., Werner, A., Wiegel, B., Wilde, F., Winkler, E., Winters, V., Wolf, S., Wolowski, J., Wright, A., Xanthopoulos, P., Yamada, H., Yamada, I., Yasuhara, R., Yokoyama, M., Zajac, J., Zarnstorff, M., Zeitler, A., Zhang, H., Zhu, J., Zilker, M., Zimbal, A., Zocco, A., Zoletnik, S., and Zuin, M.
Abstract: After completing the main construction phase of Wendelstein 7-X (W7-X) and successfully commissioning the device, first plasma operation started at the end of 2015. Integral commissioning of plasma start-up and operation using electron cyclotron resonance heating (ECRH) and an extensive set of plasma diagnostics have been completed, allowing initial physics studies during the first operational campaign. Both in helium and hydrogen, plasma breakdown was easily achieved. Gaining experience with plasma vessel conditioning, discharge lengths could be extended gradually. Eventually, discharges lasted up to 6 s, reaching an injected energy of 4 MJ, which is twice the limit originally agreed for the limiter configuration employed during the first operational campaign. At power levels of 4 MW central electron densities reached 3 1019 m-3, central electron temperatures reached values of 7 keV and ion temperatures reached just above 2 keV. Important physics studies during this first operational phase include a first assessment of power balance and energy confinement, ECRH power deposition experiments, 2nd harmonic O-mode ECRH using multi-pass absorption, and current drive experiments using electron cyclotron current drive. As in many plasma discharges the electron temperature exceeds the ion temperature significantly, these plasmas are governed by core electron root confinement showing a strong positive electric field in the plasma centre.
Published: 2017

48. 30-Day, 90-day and 1-year mortality after emergency colonic surgery

Author: Pedersen, T, Watt, S K, Tolstrup, M-B, Gögenur, I, Pedersen, T, Watt, S K, Tolstrup, M-B, and Gögenur, I
Abstract: PURPOSE: Emergency surgery is an independent risk factor in colonic surgery resulting in high 30-day mortality. The primary aim of this study was to report 30-day, 90-day and 1-year mortality rates after emergency colonic surgery, and to report factors associated with 30-day, 90-day and 1-year mortality. Second, the aim was to report 30-day postoperative complications and their relation to in-hospital mortality.METHODS: All patients undergoing acute colonic surgery in the period from May 2009 to April 2013 at Copenhagen University Hospital Herlev, Denmark, were identified. Perioperative data was collected from medical journals.RESULTS: 30-day, 90-day and 1-year mortality was 21, 30 and 41%, respectively. Age >70 years, Performance status ≥3 and resection with stoma were independent factors associated with 30-day mortality. Age >70 years, Performance status ≥3, resection with stoma and malignant disease were independent risk factors associated with 90-day mortality. Age >70 years, Performance status ≥3, resection with stoma and malignant disease were independent factors associated with 1-year mortality. Overall, 30-day complication rate was 63%, with cardiopulmonary complications leading to most postoperative deaths.CONCLUSION: Mortality and complication rates after emergency colonic surgery are high and associated with patient related risk factors that cannot be modified, but also treatment related outcomes that are modifiable. An increased focus on medical and other preventive measures should be explored in the future.
Published: 2017

49. Industrial district firms do not smile: structuring the value chain between local and global

Author: Pedersen T., Devinney T. M., Tihanyi L., Camuffo A., Bettiol, Marco, Burlina, Chiara, Chiarvesio, Maria, Di Maria, Eleonora, Pedersen T., Devinney T. M., Tihanyi L., Camuffo A., Bettiol, Marco, Burlina, Chiara, Chiarvesio, Maria, and Di Maria, Eleonora
Abstract: Defined as local manufacturing systems, industrial districts have been recognized as particularly important for the location of firms' manufacturing activities intertwined with innovation processes. The debate on the internationalization of production has stressed the low value related to manufacturing within value chain activities (smile framework), emphasizing the need to focus on high value-added activities (R&D or marketing). Following multinational enterprises' internationalization strategies, also district firms have progressively offshored their production phases in the past years. However, recent studies focused on backshoring have revamped the attention on the domestic control of production for firms' competitiveness. This chapter explores district firms' location choices for manufacturing activities between local and global. Based on an empirical analysis of about 260 Italian district firms specialized in mechanics, furniture, and fashion and supported by a case study investigation, our results show that despite district internationalization processes, a non-negligible amount of firms still carry out in-house or through outsourcing - production activities at district level. Larger firmscouple district production and long-term upstream outsourced internationalization activities. The district system confirms its role of pooling specialized competences and product know-how, being decisive for firms' innovation and responsiveness to national and international markets. Backshoring, instead, is a very limited phenomenon and linked to upgrading strategies.
Published: 2017

50. Confirmation of the topology of the Wendelstein 7-X magnetic field to better than 1:100,000

Author: Universidad de Sevilla. Departamento de Física Atómica, Molecular y Nuclear, Pedersen, T. S., Otte, M., Lazerson, S., Helander, P., Bozhenkov, Sergey A., Biedermann, Christoph, García Muñoz, Manuel, Universidad de Sevilla. Departamento de Física Atómica, Molecular y Nuclear, Pedersen, T. S., Otte, M., Lazerson, S., Helander, P., Bozhenkov, Sergey A., Biedermann, Christoph, and García Muñoz, Manuel
Abstract: Fusion energy research has in the past 40 years focused primarily on the tokamak concept, but recent advances in plasma theory and computational power have led to renewed interest in stellarators. The largest and most sophisticated stellarator in the world, Wendelstein 7-X (W7-X), has just started operation, with the aim to show that the earlier weaknesses of this concept have been addressed successfully, and that the intrinsic advantages of the concept persist, also at plasma parameters approaching those of a future fusion power plant. Here we show the first physics results, obtained before plasma operation: that the carefully tailored topology of nested magnetic surfaces needed for good confinement is realized, and that the measured deviations are smaller than one part in 100,000. This is a significant step forward in stellarator research, since it shows that the complicated and delicate magnetic topology can be created and verified with the required accuracy.
Published: 2016

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