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New biomarkers of Alzheimer's disease (AD) with a diagnostic value in preclinical and prodromal stages are urgently needed. AD-related serum autoantibodies are potential candidate biomarkers. Here, we aimed at identifying AD-related serum autoantibodies using protein microarrays and mass spectrometry-based methods. To this end, an untargeted complementary screening using high-density (42,100 antigens) and low-density (384 antigens) planar protein-epitope signature tag (PrEST) arrays and an immunoprecipitation protocol coupled to mass spectrometry analysis were used for serum autoantibody profiling. From the untargeted screening phase, 377 antigens corresponding to 338 proteins were selected for validation. Out of them, IVD, CYFIP1, and ADD2 seroreactivity was validated using 128 sera from AD patients and controls by PrEST-suspension bead arrays, and ELISA or luminescence Halotag-based bead immunoassay using full-length recombinant proteins. Importantly, IVD, CYFIP1, and ADD2 showed in combination a noticeable AD diagnostic ability. Moreover, IVD protein abundance in the prefrontal cortex was significantly two-fold higher in AD patients than in controls by western blot and immunohistochemistry, whereas CYFIP1 and ADD2 were significantly down-regulated in AD patients. The panel of AD-related autoantigens identified by a comprehensive multiomics approach may provide new insights of the disease and should help in the blood-based diagnosis of Alzheimer's disease. Mass spectrometry raw data are available in the ProteomeXchange database with the access number PXD028392., QC 20211201

This work presents a tri-band planar antenna array envisioned for assimilation into future 5G mm-wave wireless communication applications. The proposed assembly comprises of four antenna elements excited by a 1×4 T-junction power divider/Combiner and Defected Ground Structure (DGS). The antenna array presented in this work is modeled on Rogers RT/Duroid 5880 substrate with an overall size of 14 × 60 × 0.787 mm3. The frequency bands covered by the antenna system are centered at 29, 37.37 and 41 GHz with 10 dB bandwidths of 1.25, 1.3 and 2.14 GHz respectively. The peak gain attained by the antenna array is 11.8 dB. The proposed design with compact, simple and low profile assembly along with good radiation characteristics ascertains to be appropriate for mobile terminals and handheld wireless devices., Part of ISBN 9781728113227QC 20230920

In this paper, a Nonuniform fast Fourier transform (NUFFT)-based range migration algorithm (RMA) is proposed for three-dimensional (3-D) imaging with irregular planar arrays. The proposed imaging algorithm takes advantage of NUFFT to reconstruct the signal spectra in the wavenumber domain, which overcomes the constraint of irregular spatial sampling on the utilization of Fourier-based imaging algorithms. Compared to the conventional coherent summation algorithms, i.e., backprojection and Kirchhoff migration, it is a very efficient method for 3-D image formation with nonuniform spatial sampling. To demonstrate its imaging performance, some numerical simulations are presented and discussed., Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public., Microwave Sensing, Signals & Systems

In this paper, a Nonuniform fast Fourier transform (NUFFT)-based range migration algorithm (RMA) is proposed for three-dimensional (3-D) imaging with irregular planar arrays. The proposed imaging algorithm takes advantage of NUFFT to reconstruct the signal spectra in the wavenumber domain, which overcomes the constraint of irregular spatial sampling on the utilization of Fourier-based imaging algorithms. Compared to the conventional coherent summation algorithms, i.e., backprojection and Kirchhoff migration, it is a very efficient method for 3-D image formation with nonuniform spatial sampling. To demonstrate its imaging performance, some numerical simulations are presented and discussed., Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public., Microwave Sensing, Signals & Systems

Producción Científica, This paper presents the characterization of each of the MEMS microphones which form a uniform planar array used for acoustical imaging. These microphones show an esentialy flat frequency response, with a ±2dB variation between all sensors. This paper also shows the design and the acoustic characterization of the planar array of MEMS microphones. Analyzing the acoustic array characterization it was observed that as the variations of the measured beampattern, with respect to the theoretical one, are limited, it is not necessary to apply calibration techniques to the array., MINECO/FEDER, UE TEC 2015-68170-R

Producción Científica, This paper presents the characterization of each of the MEMS microphones which form a uniform planar array used for acoustical imaging. These microphones show an esentialy flat frequency response, with a ±2dB variation between all sensors. This paper also shows the design and the acoustic characterization of the planar array of MEMS microphones. Analyzing the acoustic array characterization it was observed that as the variations of the measured beampattern, with respect to the theoretical one, are limited, it is not necessary to apply calibration techniques to the array., MINECO/FEDER, UE TEC 2015-68170-R

Producción Científica, This paper presents the characterization of each of the MEMS microphones which form a uniform planar array used for acoustical imaging. These microphones show an esentialy flat frequency response, with a ±2dB variation between all sensors. This paper also shows the design and the acoustic characterization of the planar array of MEMS microphones. Analyzing the acoustic array characterization it was observed that as the variations of the measured beampattern, with respect to the theoretical one, are limited, it is not necessary to apply calibration techniques to the array., MINECO/FEDER, UE TEC 2015-68170-R

Producción Científica, This paper presents the characterization of each of the MEMS microphones which form a uniform planar array used for acoustical imaging. These microphones show an esentialy flat frequency response, with a ±2dB variation between all sensors. This paper also shows the design and the acoustic characterization of the planar array of MEMS microphones. Analyzing the acoustic array characterization it was observed that as the variations of the measured beampattern, with respect to the theoretical one, are limited, it is not necessary to apply calibration techniques to the array., MINECO/FEDER, UE TEC 2015-68170-R

Designing antenna arrays based on travelling wave structures has been studied extensively during the past couple of decades and literature on several array topologies is present. It has been an active area of research as constant improvement of antenna arrays is desired for different communication systems developed. Slotted waveguide antennas are one form of travelling wave structures which is adapted in this study due to several advantages offered over other planar array structures. Waveguide slots have been used for a couple of decades as radiating elements. Several design studies have been carried out regarding use of slots with different orientations and geometry and cascading them together to be used as array antennas. Waveguide antennas are preferred as they provide low losses in the feed structure and also offer good radiation characteristics. This study provides a design procedure for implementing a circular polarized planar antenna array based on slotted waveguide structures. The antenna is designed to work in the 19.7 - 20.2 GHz range which is the operating frequency for the downlink of satellites., zunnurain_ad@live.com,zuah10@student.bth.se

Designing antenna arrays based on travelling wave structures has been studied extensively during the past couple of decades and literature on several array topologies is present. It has been an active area of research as constant improvement of antenna arrays is desired for different communication systems developed. Slotted waveguide antennas are one form of travelling wave structures which is adapted in this study due to several advantages offered over other planar array structures. Waveguide slots have been used for a couple of decades as radiating elements. Several design studies have been carried out regarding use of slots with different orientations and geometry and cascading them together to be used as array antennas. Waveguide antennas are preferred as they provide low losses in the feed structure and also offer good radiation characteristics. This study provides a design procedure for implementing a circular polarized planar antenna array based on slotted waveguide structures. The antenna is designed to work in the 19.7 - 20.2 GHz range which is the operating frequency for the downlink of satellites., zunnurain_ad@live.com,zuah10@student.bth.se

Designing antenna arrays based on travelling wave structures has been studied extensively during the past couple of decades and literature on several array topologies is present. It has been an active area of research as constant improvement of antenna arrays is desired for different communication systems developed. Slotted waveguide antennas are one form of travelling wave structures which is adapted in this study due to several advantages offered over other planar array structures. Waveguide slots have been used for a couple of decades as radiating elements. Several design studies have been carried out regarding use of slots with different orientations and geometry and cascading them together to be used as array antennas. Waveguide antennas are preferred as they provide low losses in the feed structure and also offer good radiation characteristics. This study provides a design procedure for implementing a circular polarized planar antenna array based on slotted waveguide structures. The antenna is designed to work in the 19.7 - 20.2 GHz range which is the operating frequency for the downlink of satellites., zunnurain_ad@live.com,zuah10@student.bth.se

Designing antenna arrays based on travelling wave structures has been studied extensively during the past couple of decades and literature on several array topologies is present. It has been an active area of research as constant improvement of antenna arrays is desired for different communication systems developed. Slotted waveguide antennas are one form of travelling wave structures which is adapted in this study due to several advantages offered over other planar array structures. Waveguide slots have been used for a couple of decades as radiating elements. Several design studies have been carried out regarding use of slots with different orientations and geometry and cascading them together to be used as array antennas. Waveguide antennas are preferred as they provide low losses in the feed structure and also offer good radiation characteristics. This study provides a design procedure for implementing a circular polarized planar antenna array based on slotted waveguide structures. The antenna is designed to work in the 19.7 - 20.2 GHz range which is the operating frequency for the downlink of satellites., zunnurain_ad@live.com,zuah10@student.bth.se

Designing antenna arrays based on travelling wave structures has been studied extensively during the past couple of decades and literature on several array topologies is present. It has been an active area of research as constant improvement of antenna arrays is desired for different communication systems developed. Slotted waveguide antennas are one form of travelling wave structures which is adapted in this study due to several advantages offered over other planar array structures. Waveguide slots have been used for a couple of decades as radiating elements. Several design studies have been carried out regarding use of slots with different orientations and geometry and cascading them together to be used as array antennas. Waveguide antennas are preferred as they provide low losses in the feed structure and also offer good radiation characteristics. This study provides a design procedure for implementing a circular polarized planar antenna array based on slotted waveguide structures. The antenna is designed to work in the 19.7 - 20.2 GHz range which is the operating frequency for the downlink of satellites., zunnurain_ad@live.com,zuah10@student.bth.se

Designing antenna arrays based on travelling wave structures has been studied extensively during the past couple of decades and literature on several array topologies is present. It has been an active area of research as constant improvement of antenna arrays is desired for different communication systems developed. Slotted waveguide antennas are one form of travelling wave structures which is adapted in this study due to several advantages offered over other planar array structures. Waveguide slots have been used for a couple of decades as radiating elements. Several design studies have been carried out regarding use of slots with different orientations and geometry and cascading them together to be used as array antennas. Waveguide antennas are preferred as they provide low losses in the feed structure and also offer good radiation characteristics. This study provides a design procedure for implementing a circular polarized planar antenna array based on slotted waveguide structures. The antenna is designed to work in the 19.7 - 20.2 GHz range which is the operating frequency for the downlink of satellites., zunnurain_ad@live.com,zuah10@student.bth.se

A computer simulation of a correlator receiver was developed and exercised to study the impact of a model-based signal processing algorithm on the detection of transmitted CW and LFM pulse acoustic signals incident on a planar array of electroacoustic transducers. The model of the ocean communication channel incorporates a space-variant sound speed profile. The transducer output electrical signals are cophased by an FFT beamformer via phase weighting, and summed to form a total array output signal. The total array output signal is correlated with a delayed replica of the transmit waveform and compared to a Neyman-Pearson threshold. Receiver performance is measured using a Monte Carlo technique to estimate the probability of detection for a fixed probability of false alarm versus the signal-to-noise ratio at the input of a single transducer. White, zero-mean, Gaussian transducer noise is assumed to facilitate comparison between theoretical and simulated performance. Results indicate that model-based signal processing provides significant improvement of receiver performance., http://archive.org/details/underwatercousti1094521597, Lieutenant, United States Coast Guard, Approved for public release; distribution is unlimited.

In this paper, a technique based on hybrid particle swarm optimiser with breeding and subpopulation is presented for optimal design of reconfigurable dual-beam linear array antennas and planar arrays. In the amplitudephase synthesis, the design of a reconfigurable dual-pattern antenna array is based on finding a common amplitude distribution that can generate either a pencil or sector beam power pattern, when the phase distribution of the array is modified appropriately. The goal of this study is to introduce the hybrid model to the electromagnetic community and demonstrate its great potential in electromagnetic optimizations.

In this paper, a technique based on hybrid particle swarm optimiser with breeding and subpopulation is presented for optimal design of reconfigurable dual-beam linear array antennas and planar arrays. In the amplitudephase synthesis, the design of a reconfigurable dual-pattern antenna array is based on finding a common amplitude distribution that can generate either a pencil or sector beam power pattern, when the phase distribution of the array is modified appropriately. The goal of this study is to introduce the hybrid model to the electromagnetic community and demonstrate its great potential in electromagnetic optimizations.

In this paper, a technique based on hybrid particle swarm optimiser with breeding and subpopulation is presented for optimal design of reconfigurable dual-beam linear array antennas and planar arrays. In the amplitudephase synthesis, the design of a reconfigurable dual-pattern antenna array is based on finding a common amplitude distribution that can generate either a pencil or sector beam power pattern, when the phase distribution of the array is modified appropriately. The goal of this study is to introduce the hybrid model to the electromagnetic community and demonstrate its great potential in electromagnetic optimizations.

In this paper, a technique based on hybrid particle swarm optimiser with breeding and subpopulation is presented for optimal design of reconfigurable dual-beam linear array antennas and planar arrays. In the amplitudephase synthesis, the design of a reconfigurable dual-pattern antenna array is based on finding a common amplitude distribution that can generate either a pencil or sector beam power pattern, when the phase distribution of the array is modified appropriately. The goal of this study is to introduce the hybrid model to the electromagnetic community and demonstrate its great potential in electromagnetic optimizations.

In this paper, a technique based on hybrid particle swarm optimiser with breeding and subpopulation is presented for optimal design of reconfigurable dual-beam linear array antennas and planar arrays. In the amplitudephase synthesis, the design of a reconfigurable dual-pattern antenna array is based on finding a common amplitude distribution that can generate either a pencil or sector beam power pattern, when the phase distribution of the array is modified appropriately. The goal of this study is to introduce the hybrid model to the electromagnetic community and demonstrate its great potential in electromagnetic optimizations.

This report documents a computer program which simulates the beamforming process of a planar array. It uses the physical characteristics, electrical shading characteristics and other factors to obtain detailed information of theoretical beam structures. Amplitude and phase coefficients can be varied to study main and side lobe structures for steered/unsteered and/or spread/unspread beam patterns.

It is well known that classical ECM techniques against an incoming active missile attack is effective only at distances where the jamming signal to missile return signal ratio is high. There is no guarantee that it will work well against all missiles. As the missiles get closer to the target, the effectiveness of classical ECM techniques is reduced. Hence, there is a need to design a short range ECM system that is effective at medium range and increases its countermeasure capabilities as the range shrinks. The US Army is considering a high power, mobile ECM system capable of delivering up to 5 GW of peak power at 10 GHz. The narrow beamwidth of this system creates a very high peak power density of the order of 10-20 W/cm² at 10 Km distance. With this amount of concentrated energy, it is capable of damaging or degrading the highly sensitive sensors of the missile and causing the missile to lose track of its target. The purpose of this project is first, to evaluate the various possible array types which must meet a far field peak power density requirement subject to a constraint on maximum aperture E-field strength. At the same time, the sidelobe and backlobe levels should not cause radiation hazard to the operators of the system. After an array design is chosen, the whole vehicular structure is modeled and near field patterns are examined to determine the likely radiation hazard zone. This project is based on the usage of the Numerical Electromagnetic Code - Basic Scattering Code (NEC-BSC) from the Ohio State University. Four additional software programs are written to support the code. The evaluation shows that Uniform - Cosine tapering offered the lowest sidelobe and backlobe level in the near field and yet met the far field requirement and maximum aperture E-field constraint. With the vehicular structure included, the system has a safety margin of more than 27 dB below the recommended radiation hazard limit near ground level., Harry Diamond Laboratories MIPR R85-103, http://archive.org/details/radiationhazarde1094522448, Harry Diamond Laboratories MIPR R85-103, Ministry of Defence, Singapore, Approved for public release; distribution is unlimited.

A general, modular, pulse propagation model for underwater acoustics that is based on linear systems theory for sound-speed profiles as a function of depth is presented. The development and computer implementation of the model, together with results from preliminary computer simulation studies involving the transmission of CW and LFM pulses from a planar array of complex weighted point sources is reported. The studies examined free-space propagation problems (i.e., no boundaries) in homogeneous and inhomogeneous media using a transfer function of the ocean medium based on the WKB approximation. The two main outputs from the model are the predicted complex acoustic field as a function of frequency and spatial location and the time-domain output electrical signal from each element in a receive planar array., http://archive.org/details/anocemediumpulse1094527177, Lieutenant, Royal Australian Navy, Approved for public release; distribution is unlimited.