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24 results on '"Schütz, H"'

3. Assessing goodness-of-fit for evaluation of dose-proportionality

Author

Wolfsegger, M.J., Bauer, A., Labes, D., Schütz, H., Vonk, R., Lang, B., Lehr, S., Jaki, T.F., Engl, W., Hale, M.D., Wolfsegger, M.J., Bauer, A., Labes, D., Schütz, H., Vonk, R., Lang, B., Lehr, S., Jaki, T.F., Engl, W., and Hale, M.D.

Abstract

For the clinical development of a new drug, the determination of dose-proportionality is an essential part of the pharmacokinetic evaluations, which may provide early indications of non-linear pharmacokinetics and may help to identify sub-populations with divergent clearances. Prior to making any conclusions regarding dose-proportionality, the goodness-of-fit of the model must be assessed to evaluate the model performance. We propose the use of simulation-based visual predictive checks to improve the validity of dose-proportionality conclusions for complex designs. We provide an illustrative example and include a table to facilitate review by regulatory authorities.

Published
2021

4. Assessing goodness-of-fit for evaluation of dose-proportionality

Author

Wolfsegger, M.J., Bauer, A., Labes, D., Schütz, H., Vonk, R., Lang, B., Lehr, S., Jaki, T.F., Engl, W., Hale, M.D., Wolfsegger, M.J., Bauer, A., Labes, D., Schütz, H., Vonk, R., Lang, B., Lehr, S., Jaki, T.F., Engl, W., and Hale, M.D.

Abstract

For the clinical development of a new drug, the determination of dose-proportionality is an essential part of the pharmacokinetic evaluations, which may provide early indications of non-linear pharmacokinetics and may help to identify sub-populations with divergent clearances. Prior to making any conclusions regarding dose-proportionality, the goodness-of-fit of the model must be assessed to evaluate the model performance. We propose the use of simulation-based visual predictive checks to improve the validity of dose-proportionality conclusions for complex designs. We provide an illustrative example and include a table to facilitate review by regulatory authorities.

Published
2021

5. GRIN2B encephalopathy: Novel findings on phenotype, variant clustering, functional consequences and treatment aspects

Author

Platzer, K, Yuan, H, Schütz, H, Winschel, A, Chen, W, Hu, C, Kusumoto, H, Heyne, HO, Helbig, KL, Tang, S, Willing, MC, Tinkle, BT, Adams, DJ, Depienne, C, Keren, B, Mignot, C, Frengen, E, Strømme, P, Biskup, S, Döcker, D, Strom, TM, Mefford, HC, Myers, CT, Muir, AM, LaCroix, A, Sadleir, L, Scheffer, IE, Brilstra, E, van Haelst, MM, van der Smagt, JJ, Bok, LA, Møller, RS, Jensen, UB, Millichap, JJ, Berg, AT, Goldberg, EM, De Bie, I, Fox, S, Major, P, Jones, JR, Zackai, EH, Abou Jamra, R, Rolfs, A, Leventer, RJ, Lawson, JA, Roscioli, T, Jansen, FE, Ranza, E, Korff, CM, Lehesjoki, AE, Courage, C, Linnankivi, T, Smith, DR, Stanley, C, Mintz, M, McKnight, D, Decker, A, Tan, WH, Tarnopolsky, MA, Brady, LI, Wolff, M, Dondit, L, Pedro, HF, Parisotto, SE, Jones, KL, Patel, AD, Franz, DN, Vanzo, R, Marco, E, Ranells, JD, Di Donato, N, Dobyns, WB, Laube, B, Traynelis, SF, Lemke, JR, Platzer, K, Yuan, H, Schütz, H, Winschel, A, Chen, W, Hu, C, Kusumoto, H, Heyne, HO, Helbig, KL, Tang, S, Willing, MC, Tinkle, BT, Adams, DJ, Depienne, C, Keren, B, Mignot, C, Frengen, E, Strømme, P, Biskup, S, Döcker, D, Strom, TM, Mefford, HC, Myers, CT, Muir, AM, LaCroix, A, Sadleir, L, Scheffer, IE, Brilstra, E, van Haelst, MM, van der Smagt, JJ, Bok, LA, Møller, RS, Jensen, UB, Millichap, JJ, Berg, AT, Goldberg, EM, De Bie, I, Fox, S, Major, P, Jones, JR, Zackai, EH, Abou Jamra, R, Rolfs, A, Leventer, RJ, Lawson, JA, Roscioli, T, Jansen, FE, Ranza, E, Korff, CM, Lehesjoki, AE, Courage, C, Linnankivi, T, Smith, DR, Stanley, C, Mintz, M, McKnight, D, Decker, A, Tan, WH, Tarnopolsky, MA, Brady, LI, Wolff, M, Dondit, L, Pedro, HF, Parisotto, SE, Jones, KL, Patel, AD, Franz, DN, Vanzo, R, Marco, E, Ranells, JD, Di Donato, N, Dobyns, WB, Laube, B, Traynelis, SF, and Lemke, JR

Abstract

Background: We aimed for a comprehensive delineation of genetic, functional and phenotypic aspects of GRIN2B encephalopathy and explored potential prospects of personalised medicine. Methods: Data of 48 individuals with de novo GRIN2B variants were collected from several diagnostic and research cohorts, as well as from 43 patients from the literature. Functional consequences and response to memantine treatment were investigated in vitro and eventually translated into patient care. Results: Overall, de novo variants in 86 patients were classified as pathogenic/likely pathogenic. Patients presented with neurodevelopmental disorders and a spectrum of hypotonia, movement disorder, cortical visual impairment, cerebral volume loss and epilepsy. Six patients presented with a consistent malformation of cortical development (MCD) intermediate between tubulinopathies and polymicrogyria. Missense variants cluster in transmembrane segments and ligand-binding sites. Functional consequences of variants were diverse, revealing various potential gain-of-function and loss-of-function mechanisms and a retained sensitivity to the use-dependent blocker memantine. However, an objectifiable beneficial treatment response in the respective patients still remains to be demonstrated. Conclusions: In addition to previously known features of intellectual disability, epilepsy and autism, we found evidence that GRIN2B encephalopathy is also frequently associated with movement disorder, cortical visual impairment and MCD revealing novel phenotypic consequences of channelopathies.

Published
2017

6. The detection of neutrino interactions in the emulsion/lead target of the OPERA experiment

Author

Agafonova, N, Anokhina, A, Aoki, S, Ariga, A, Ariga, T, Arrabito, L, Autiero, D, Badertscher, A, Bagulya, A, Bersani Greggio, F, Bertolin, A, Besnier, M, Bick, D, Boyarkin, V, Bozza, C, Brugière, T, Brugnera, R, Brunetti, G, Buontempo, S, Carrara, E, Cazes, A, Chaussard, L, Chernyavsky, M, Chiarella, V, Chon-Sen, N, Chukanov, A, Cozzi, M, D'Amato, G, Dal Corso, F, D'Ambrosio, N, De Lellis, G, Déclais, Y, De Serio, M, Di Capua, F, Di Ferdinando, D, Di Giovanni, A, Di Marco, N, Di Troia, C, Dmitrievski, S, Dominjon, A, Dracos, M, Duchesneau, D, Dusini, S, Ebert, J, Egorov, O, Enikeev, R, Ereditato, A, Esposito, L, Favier, J, Felici, G, Ferber, T, Fini, R, Frekers, D, Fukuda, T, Fukushima, C, Galkin, V, Garfagnini, A, Giacomelli, G, Giorgini, M, Goellnitz, C, Goeltzenlichter, T, Goldberg, J, Golubkov, D, Gornushkin, Y, Grella, G, Grianti, F, Guler, M, Gustavino, C, Hagner, C, Hamada, K, Hara, T, Hierholzer, M, Hoshino, K, Ieva, M, Jakovcic, K, Janutta, B, Jollet, C, Juget, F, Kazuyama, M, Kim, S, Kimura, M, Kitagawa, N, Klicek, B, Knuesel, J, Kodama, K, Kolev, D, Komatsu, M, Kose, U, Krasnoperov, A, Kreslo, I, Krumstein, Z, Kubota, H, Kutsenov, V, Kuznetsov, V, Laktineh, I, Lazzaro, C, Lenkeit, J, Ljubicic, A, Longhin, A, Lutter, G, Malgin, A, Manai, K, Mandrioli, G, Marotta, A, Marteau, J, Matsuo, T, Matveev, V, Mauri, N, Medinaceli, E, Meisel, F, Meregaglia, A, Messina, M, Migliozzi, P, Miyamoto, S, Monacelli, P, Morishima, K, Moser, U, Muciaccia, M, Naganawa, N, Naka, T, Nakamura, M, Nakano, T, Nikitina, V, Niwa, K, Nonoyama, Y, Nozdrin, A, Ogawa, S, Olchevski, A, Orlova, G, Osedlo, V, Ossetski, D, Paniccia, M, Paoloni, A, Park, B, Park, I, Pastore, A, Patrizii, L, Pennacchio, E, Pessard, H, Pilipenko, V, Pistillo, C, Polukhina, N, Pozzato, M, Pretzl, K, Publichenko, P, Pupilli, F, Rescigno, R, Rizhikov, D, Roganova, T, Romano, G, Rosa, G, Rostovtseva, I, Rubbia, A, Russo, A, Ryasny, V, Ryazhskaya, O, Sadovski, A, Sato, O, Sato, Y, Saveliev, V, Schembri, A, Schmidt Parzefall, W, Schroeder, H, Schütz, H, Schuler, J, Scotto Lavina, L, Shibuya, H, Simone, S, Sioli, M, Sirignano, C, Sirri, G, Song, J, Spinetti, M, Stanco, L, Starkov, N, Stipcevic, M, Strauss, T, Strolin, P, Sugonyaev, V, Takahashi, S, Tereschenko, V, Terranova, F, Tezuka, I, Tioukov, V, Tolun, P, Tsarev, V, Tsenov, R, Tufanli, S, Ushida, N, Verguilov, V, Vilain, P, Vladimirov, M, Votano, L, Vuilleumier, J, Wilquet, G, Wonsak, B, Yakushev, V, Yoon, C, Yoshioka, T, Yoshida, J, Zaitsev, Y, Zghiche, A, Zimmermann, R, Agafonova, N., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Arrabito, L., Autiero, D., Badertscher, A., Bagulya, A., Bersani Greggio, F., Bertolin, A., Besnier, M., Bick, D., Boyarkin, V., Bozza, C., Brugière, T., Brugnera, R., Brunetti, G., Buontempo, S., Carrara, E., Cazes, A., Chaussard, L., Chernyavsky, M., Chiarella, V., Chon-Sen, N., Chukanov, A., Cozzi, M., D'amato, G., Dal Corso, F., D'ambrosio, N., De Lellis, G., Déclais, Y., De Serio, M., Di Capua, F., Di Ferdinando, D., Di Giovanni, A., Di Marco, N., Di Troia, C., Dmitrievski, S., Dominjon, A., Dracos, M., Duchesneau, D., Dusini, S., Ebert, J., Egorov, O., Enikeev, R., Ereditato, A., Esposito, L. S., Favier, J., Felici, G., Ferber, T., Fini, R., Frekers, D., Fukuda, T., Fukushima, C., Galkin, V. I., Galkin, V. A., Garfagnini, A., Giacomelli, G., Giorgini, M., Goellnitz, C., Goeltzenlichter, T., Goldberg, J., Golubkov, D., Gornushkin, Y., Grella, G., Grianti, F., Guler, M., Gustavino, C., Hagner, C., Hamada, K., Hara, T., Hierholzer, M., Hoshino, K., Ieva, M., Jakovcic, K., Janutta, B., Jollet, C., Juget, F., Kazuyama, M., Kim, S. H., Kimura, M., Kitagawa, N., Klicek, B., Knuesel, J., Kodama, K., Kolev, D., Komatsu, M., Kose, U., Krasnoperov, A., Kreslo, I., Krumstein, Z., Kubota, H., Kutsenov, V. V., Kuznetsov, V. A., Laktineh, I., Lazzaro, C., Lenkeit, J., Ljubicic, A., Longhin, A., Lutter, G., Malgin, A., Manai, K., Mandrioli, G., Marotta, A., Marteau, J., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meisel, F., Meregaglia, A., Messina, M., Migliozzi, P., Miyamoto, S., Monacelli, P., Morishima, K., Moser, U., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Nikitina, V., Niwa, K., Nonoyama, Y., Nozdrin, A., Ogawa, S., Olchevski, A., Orlova, G., Osedlo, V., Ossetski, D., Paniccia, M., Paoloni, A., Park, B. D., Park, I. G., Pastore, A., Patrizii, L., Pennacchio, E., Pessard, H., Pilipenko, V., Pistillo, C., Polukhina, N., Pozzato, M., Pretzl, K., Publichenko, P., Pupilli, F., Rescigno, R., Rizhikov, D., Roganova, T., Romano, G., Rosa, G., Rostovtseva, I., Rubbia, A., Russo, A., Ryasny, V., Ryazhskaya, O., Sadovski, A., Sato, O., Sato, Y., Saveliev, V., Schembri, A., Schmidt Parzefall, W., Schroeder, H., Schütz, H. U., Schuler, J., Scotto Lavina, L., Shibuya, H., Simone, S., Sioli, M., Sirignano, C., Sirri, G., Song, J. S., Spinetti, M., Stanco, L., Starkov, N., Stipcevic, M., Strauss, T., Strolin, P., Sugonyaev, V., Takahashi, S., Tereschenko, V., Terranova, F., Tezuka, I., Tioukov, V., Tolun, P., Tsarev, V., Tsenov, R., Tufanli, S., Ushida, N., Verguilov, V., Vilain, P., Vladimirov, M., Votano, L., Vuilleumier, J. L., Wilquet, G., Wonsak, B., Yakushev, V., Yoon, C. S., Yoshioka, T., Yoshida, J., Zaitsev, Y., Zghiche, A., Zimmermann, R., Agafonova, N, Anokhina, A, Aoki, S, Ariga, A, Ariga, T, Arrabito, L, Autiero, D, Badertscher, A, Bagulya, A, Bersani Greggio, F, Bertolin, A, Besnier, M, Bick, D, Boyarkin, V, Bozza, C, Brugière, T, Brugnera, R, Brunetti, G, Buontempo, S, Carrara, E, Cazes, A, Chaussard, L, Chernyavsky, M, Chiarella, V, Chon-Sen, N, Chukanov, A, Cozzi, M, D'Amato, G, Dal Corso, F, D'Ambrosio, N, De Lellis, G, Déclais, Y, De Serio, M, Di Capua, F, Di Ferdinando, D, Di Giovanni, A, Di Marco, N, Di Troia, C, Dmitrievski, S, Dominjon, A, Dracos, M, Duchesneau, D, Dusini, S, Ebert, J, Egorov, O, Enikeev, R, Ereditato, A, Esposito, L, Favier, J, Felici, G, Ferber, T, Fini, R, Frekers, D, Fukuda, T, Fukushima, C, Galkin, V, Garfagnini, A, Giacomelli, G, Giorgini, M, Goellnitz, C, Goeltzenlichter, T, Goldberg, J, Golubkov, D, Gornushkin, Y, Grella, G, Grianti, F, Guler, M, Gustavino, C, Hagner, C, Hamada, K, Hara, T, Hierholzer, M, Hoshino, K, Ieva, M, Jakovcic, K, Janutta, B, Jollet, C, Juget, F, Kazuyama, M, Kim, S, Kimura, M, Kitagawa, N, Klicek, B, Knuesel, J, Kodama, K, Kolev, D, Komatsu, M, Kose, U, Krasnoperov, A, Kreslo, I, Krumstein, Z, Kubota, H, Kutsenov, V, Kuznetsov, V, Laktineh, I, Lazzaro, C, Lenkeit, J, Ljubicic, A, Longhin, A, Lutter, G, Malgin, A, Manai, K, Mandrioli, G, Marotta, A, Marteau, J, Matsuo, T, Matveev, V, Mauri, N, Medinaceli, E, Meisel, F, Meregaglia, A, Messina, M, Migliozzi, P, Miyamoto, S, Monacelli, P, Morishima, K, Moser, U, Muciaccia, M, Naganawa, N, Naka, T, Nakamura, M, Nakano, T, Nikitina, V, Niwa, K, Nonoyama, Y, Nozdrin, A, Ogawa, S, Olchevski, A, Orlova, G, Osedlo, V, Ossetski, D, Paniccia, M, Paoloni, A, Park, B, Park, I, Pastore, A, Patrizii, L, Pennacchio, E, Pessard, H, Pilipenko, V, Pistillo, C, Polukhina, N, Pozzato, M, Pretzl, K, Publichenko, P, Pupilli, F, Rescigno, R, Rizhikov, D, Roganova, T, Romano, G, Rosa, G, Rostovtseva, I, Rubbia, A, Russo, A, Ryasny, V, Ryazhskaya, O, Sadovski, A, Sato, O, Sato, Y, Saveliev, V, Schembri, A, Schmidt Parzefall, W, Schroeder, H, Schütz, H, Schuler, J, Scotto Lavina, L, Shibuya, H, Simone, S, Sioli, M, Sirignano, C, Sirri, G, Song, J, Spinetti, M, Stanco, L, Starkov, N, Stipcevic, M, Strauss, T, Strolin, P, Sugonyaev, V, Takahashi, S, Tereschenko, V, Terranova, F, Tezuka, I, Tioukov, V, Tolun, P, Tsarev, V, Tsenov, R, Tufanli, S, Ushida, N, Verguilov, V, Vilain, P, Vladimirov, M, Votano, L, Vuilleumier, J, Wilquet, G, Wonsak, B, Yakushev, V, Yoon, C, Yoshioka, T, Yoshida, J, Zaitsev, Y, Zghiche, A, Zimmermann, R, Agafonova, N., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Arrabito, L., Autiero, D., Badertscher, A., Bagulya, A., Bersani Greggio, F., Bertolin, A., Besnier, M., Bick, D., Boyarkin, V., Bozza, C., Brugière, T., Brugnera, R., Brunetti, G., Buontempo, S., Carrara, E., Cazes, A., Chaussard, L., Chernyavsky, M., Chiarella, V., Chon-Sen, N., Chukanov, A., Cozzi, M., D'amato, G., Dal Corso, F., D'ambrosio, N., De Lellis, G., Déclais, Y., De Serio, M., Di Capua, F., Di Ferdinando, D., Di Giovanni, A., Di Marco, N., Di Troia, C., Dmitrievski, S., Dominjon, A., Dracos, M., Duchesneau, D., Dusini, S., Ebert, J., Egorov, O., Enikeev, R., Ereditato, A., Esposito, L. S., Favier, J., Felici, G., Ferber, T., Fini, R., Frekers, D., Fukuda, T., Fukushima, C., Galkin, V. I., Galkin, V. A., Garfagnini, A., Giacomelli, G., Giorgini, M., Goellnitz, C., Goeltzenlichter, T., Goldberg, J., Golubkov, D., Gornushkin, Y., Grella, G., Grianti, F., Guler, M., Gustavino, C., Hagner, C., Hamada, K., Hara, T., Hierholzer, M., Hoshino, K., Ieva, M., Jakovcic, K., Janutta, B., Jollet, C., Juget, F., Kazuyama, M., Kim, S. H., Kimura, M., Kitagawa, N., Klicek, B., Knuesel, J., Kodama, K., Kolev, D., Komatsu, M., Kose, U., Krasnoperov, A., Kreslo, I., Krumstein, Z., Kubota, H., Kutsenov, V. V., Kuznetsov, V. A., Laktineh, I., Lazzaro, C., Lenkeit, J., Ljubicic, A., Longhin, A., Lutter, G., Malgin, A., Manai, K., Mandrioli, G., Marotta, A., Marteau, J., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meisel, F., Meregaglia, A., Messina, M., Migliozzi, P., Miyamoto, S., Monacelli, P., Morishima, K., Moser, U., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Nikitina, V., Niwa, K., Nonoyama, Y., Nozdrin, A., Ogawa, S., Olchevski, A., Orlova, G., Osedlo, V., Ossetski, D., Paniccia, M., Paoloni, A., Park, B. D., Park, I. G., Pastore, A., Patrizii, L., Pennacchio, E., Pessard, H., Pilipenko, V., Pistillo, C., Polukhina, N., Pozzato, M., Pretzl, K., Publichenko, P., Pupilli, F., Rescigno, R., Rizhikov, D., Roganova, T., Romano, G., Rosa, G., Rostovtseva, I., Rubbia, A., Russo, A., Ryasny, V., Ryazhskaya, O., Sadovski, A., Sato, O., Sato, Y., Saveliev, V., Schembri, A., Schmidt Parzefall, W., Schroeder, H., Schütz, H. U., Schuler, J., Scotto Lavina, L., Shibuya, H., Simone, S., Sioli, M., Sirignano, C., Sirri, G., Song, J. S., Spinetti, M., Stanco, L., Starkov, N., Stipcevic, M., Strauss, T., Strolin, P., Sugonyaev, V., Takahashi, S., Tereschenko, V., Terranova, F., Tezuka, I., Tioukov, V., Tolun, P., Tsarev, V., Tsenov, R., Tufanli, S., Ushida, N., Verguilov, V., Vilain, P., Vladimirov, M., Votano, L., Vuilleumier, J. L., Wilquet, G., Wonsak, B., Yakushev, V., Yoon, C. S., Yoshioka, T., Yoshida, J., Zaitsev, Y., Zghiche, A., and Zimmermann, R.

Abstract

The OPERA neutrino detector in the underground Gran Sasso Laboratory (LNGS) was designed to perform the first detection of neutrino oscillations in appearance mode through the study of Î1⁄2Î1⁄4→ Î1⁄2Ï„oscillations. The apparatus consists of an emulsion/lead target complemented by electronic detectors and it is placed in the high energy long-baseline CERN to LNGS beam (CNGS) 730 km away from the neutrino source. Runs with CNGS neutrinos were successfully carried out in 2007 and 2008 with the detector fully operational with its related facilities for the emulsion handling and analysis. After a brief description of the beam and of the experimental setup we report on the collection, reconstruction and analysis procedures of first samples of neutrino interaction events. © 2009 IOP Publishing Ltd and SISSA.

Published
2009

7. Combined electron cyclotron emission and heating for the suppression of magnetic islands in fusion plasmas

Author

van den Brand, H., de Baar, M.R., Hennen, B.A., Oosterbeek, J.W., Bongers, W.A., Westerhof, E., Kasparek, W., Doelman, N., Klop, W.A., Giannone, L., Stober, J.K., Monaco, F., Schütz, H., Wagner, D., van den Brand, H., de Baar, M.R., Hennen, B.A., Oosterbeek, J.W., Bongers, W.A., Westerhof, E., Kasparek, W., Doelman, N., Klop, W.A., Giannone, L., Stober, J.K., Monaco, F., Schütz, H., and Wagner, D.

Abstract

In a tokamak, magnetic islands need to be suppressed. Suppression is possible with electron cyclotron heating (ECH), which can be positioned using electron cyclotron emission (ECE) temperature measurements. A set-up to detect ECE in the line of sight of ECH has been built for the TEXTOR tokamak and the ASDEX Upgrade tokamak. In TEXTOR, a dielectric filter was used to separate low power ECE from high power ECH and successful aiming of ECH and suppression of a magnetic island could be demonstrated. At ASDEX Upgrade, a fast directional switch (FADIS) was used to separate ECE from ECH. Measurements of magnetic islands at ASDEX Upgrade are presented. The applicability of these measurements for magnetic island detection is discussed.

Published
2015

8. Commissioning of inline ECE system within waveguide based ECRH transmission systems on ASDEX upgrade

Author

Bongers, W.A., Kasparek, W., Doelman, N., van den Braber, R., van den Brand, H., Meo, F., de Baar, M.R., Amerongen, F.J., Donné, A.J.H., Elzendoorn, B.S.Q., Erckmann, V., Goede, A.P.H., Giannone, L., Grünwald, G., Hollman, F., Kaas, G., Krijger, B., Michel, G., Lubyako, L., Monaco, F., Noke, F., Petelin, M., Plaum, B., Purps, F., ten Pierik, J.G.W., Schüller, C., Slob, J.W., Stober, J.K., Schütz, H., Wagner, D., Westerhof, E., Ronden, D.M.S., Bongers, W.A., Kasparek, W., Doelman, N., van den Braber, R., van den Brand, H., Meo, F., de Baar, M.R., Amerongen, F.J., Donné, A.J.H., Elzendoorn, B.S.Q., Erckmann, V., Goede, A.P.H., Giannone, L., Grünwald, G., Hollman, F., Kaas, G., Krijger, B., Michel, G., Lubyako, L., Monaco, F., Noke, F., Petelin, M., Plaum, B., Purps, F., ten Pierik, J.G.W., Schüller, C., Slob, J.W., Stober, J.K., Schütz, H., Wagner, D., Westerhof, E., and Ronden, D.M.S.

Abstract

A CW capable inline electron cyclotron emission (ECE) separation system for feedback control, featuring oversized corrugated waveguides, is commissioned on ASDEX upgrade (AUG). The system is based on a combination of a polarization independent, non-resonant, Mach-Zehnder diplexer equipped with dielectric plate beam splitters [2, 3] employed as corrugated oversized waveguide filter, and a resonant Fast Directional Switch, FADIS [4, 5, 6, 7] as ECE/ECCD separation system. This paper presents an overview of the system, the low power characterisation tests and first high power commissioning on AUG.

Published
2012

9. Commissioning of inline ECE system within waveguide based ECRH transmission systems on ASDEX upgrade

Author

Bongers, W.A., Kasparek, W., Doelman, N., van den Braber, R., van den Brand, H., Meo, F., de Baar, M.R., Amerongen, F.J., Donné, A.J.H., Elzendoorn, B.S.Q., Erckmann, V., Goede, A.P.H., Giannone, L., Grünwald, G., Hollman, F., Kaas, G., Krijger, B., Michel, G., Lubyako, L., Monaco, F., Noke, F., Petelin, M., Plaum, B., Purps, F., ten Pierik, J.G.W., Schüller, C., Slob, J.W., Stober, J.K., Schütz, H., Wagner, D., Westerhof, E., Ronden, D.M.S., Bongers, W.A., Kasparek, W., Doelman, N., van den Braber, R., van den Brand, H., Meo, F., de Baar, M.R., Amerongen, F.J., Donné, A.J.H., Elzendoorn, B.S.Q., Erckmann, V., Goede, A.P.H., Giannone, L., Grünwald, G., Hollman, F., Kaas, G., Krijger, B., Michel, G., Lubyako, L., Monaco, F., Noke, F., Petelin, M., Plaum, B., Purps, F., ten Pierik, J.G.W., Schüller, C., Slob, J.W., Stober, J.K., Schütz, H., Wagner, D., Westerhof, E., and Ronden, D.M.S.

Abstract

A CW capable inline electron cyclotron emission (ECE) separation system for feedback control, featuring oversized corrugated waveguides, is commissioned on ASDEX upgrade (AUG). The system is based on a combination of a polarization independent, non-resonant, Mach-Zehnder diplexer equipped with dielectric plate beam splitters [2, 3] employed as corrugated oversized waveguide filter, and a resonant Fast Directional Switch, FADIS [4, 5, 6, 7] as ECE/ECCD separation system. This paper presents an overview of the system, the low power characterisation tests and first high power commissioning on AUG.

Published
2012

10. Commissioning of inline ECE system within waveguide based ECRH transmission systems on ASDEX upgrade

Author

Bongers, W. A., Kasparek, W., Doelman, N., van den Braber, R., van den Brand, H., Meo, Fernando, de Baar, M. R., Amerongen, F. J., Donne, A. J. H., Elzendoorn, B. S. Q., Erckmann, V., Goede, A. P. H., Giannone, L., Grünwald, G., Hollman, F., Kaas, G., Krijger, B., Michel, G., Lubyako, L., Monaco, F., Noke, F., Petelin, M., Plaum, B., Purps, F., ten Pierik, J. G. W., Schüller, C., Slob, J. W., Stober, J. K., Schütz, H., Wagner, D., Westerhof, E., Ronden, D. M. S., Bongers, W. A., Kasparek, W., Doelman, N., van den Braber, R., van den Brand, H., Meo, Fernando, de Baar, M. R., Amerongen, F. J., Donne, A. J. H., Elzendoorn, B. S. Q., Erckmann, V., Goede, A. P. H., Giannone, L., Grünwald, G., Hollman, F., Kaas, G., Krijger, B., Michel, G., Lubyako, L., Monaco, F., Noke, F., Petelin, M., Plaum, B., Purps, F., ten Pierik, J. G. W., Schüller, C., Slob, J. W., Stober, J. K., Schütz, H., Wagner, D., Westerhof, E., and Ronden, D. M. S.

Abstract

A CW capable inline electron cyclotron emission (ECE) separation system for feedback control, featuring oversized corrugated waveguides, is commissioned on ASDEX upgrade (AUG). The system is based on a combination of a polarization independent, non-resonant, Mach-Zehnder diplexer equipped with dielectric plate beam splitters [2, 3] employed as corrugated oversized waveguide filter, and a resonant Fast Directional Switch, FADIS [4, 5, 6, 7] as ECE/ECCD separation system. This paper presents an overview of the system, the low power characterisation tests and first high power commissioning on AUG.

Published
2012

11. Commissioning of inline ECE system within waveguide based ECRH transmission systems on ASDEX upgrade

Author

Bongers, W. A., Kasparek, W., Doelman, N., van den Braber, R., van den Brand, H., Meo, Fernando, de Baar, M. R., Amerongen, F. J., Donne, A. J. H., Elzendoorn, B. S. Q., Erckmann, V., Goede, A. P. H., Giannone, L., Grünwald, G., Hollman, F., Kaas, G., Krijger, B., Michel, G., Lubyako, L., Monaco, F., Noke, F., Petelin, M., Plaum, B., Purps, F., ten Pierik, J. G. W., Schüller, C., Slob, J. W., Stober, J. K., Schütz, H., Wagner, D., Westerhof, E., Ronden, D. M. S., Bongers, W. A., Kasparek, W., Doelman, N., van den Braber, R., van den Brand, H., Meo, Fernando, de Baar, M. R., Amerongen, F. J., Donne, A. J. H., Elzendoorn, B. S. Q., Erckmann, V., Goede, A. P. H., Giannone, L., Grünwald, G., Hollman, F., Kaas, G., Krijger, B., Michel, G., Lubyako, L., Monaco, F., Noke, F., Petelin, M., Plaum, B., Purps, F., ten Pierik, J. G. W., Schüller, C., Slob, J. W., Stober, J. K., Schütz, H., Wagner, D., Westerhof, E., and Ronden, D. M. S.

Abstract

A CW capable inline electron cyclotron emission (ECE) separation system for feedback control, featuring oversized corrugated waveguides, is commissioned on ASDEX upgrade (AUG). The system is based on a combination of a polarization independent, non-resonant, Mach-Zehnder diplexer equipped with dielectric plate beam splitters [2, 3] employed as corrugated oversized waveguide filter, and a resonant Fast Directional Switch, FADIS [4, 5, 6, 7] as ECE/ECCD separation system. This paper presents an overview of the system, the low power characterisation tests and first high power commissioning on AUG.

Published
2012

12. Experiments on upwards gas/liquid flow in vertical pipes

Author

Schütz, H., Pietruske, P., Manera, A., Carl, H., Beyer, M., Prasser, H.-M., Schütz, H., Pietruske, P., Manera, A., Carl, H., Beyer, M., and Prasser, H.-M.

Abstract

Two-phase flow experiments at vertical pipes are much suitable for studying the action of different constitutive relations characterizing the momentum exchange at the gas/liquid interface as well as the dynamic behaviour of the gas/liquid interface itself. The flow can be observed in its movement along the pipe and, in particular, within the shear field close to the pipe wall over a considerable vertical distance and, consequently, over a comparatively long time without the immediate separation of gas and liquid characteristic for horizontal flows. Wire-mesh sensors, which were the working horse in the described experiments, supplied sequences of instantaneous two-dimensional gas fraction distributions with a high-resolution in space and time. This allows to derive from the data not only void fraction and bubble velocity profiles, but also bubble size distributions, bubble-size resolved radial gas fraction profiles as well as the axial evolution of these distributions. An interfacial surface reconstruction algorithm was developed in order to extract the extension of interfacial area from the wire-mesh sensor data. The sensors were upgraded to withstand parameters that are close to nuclear reactor conditions. Most of the experiments were performed for both air/water flow at ambient pressure and steam/water flow of up to 6.5 MPa at identical combinations of the gas and liquid superficial velocities. This offers excellent conditions for studying the influence of the fluid properties.

Published
2010

13. Experiments on upwards gas/liquid flow in vertical pipes

Author

Schütz, H., Pietruske, P., Manera, A., Carl, H., Beyer, M., Prasser, H.-M., Schütz, H., Pietruske, P., Manera, A., Carl, H., Beyer, M., and Prasser, H.-M.

Abstract

Two-phase flow experiments at vertical pipes are much suitable for studying the action of different constitutive relations characterizing the momentum exchange at the gas/liquid interface as well as the dynamic behaviour of the gas/liquid interface itself. The flow can be observed in its movement along the pipe and, in particular, within the shear field close to the pipe wall over a considerable vertical distance and, consequently, over a comparatively long time without the immediate separation of gas and liquid characteristic for horizontal flows. Wire-mesh sensors, which were the working horse in the described experiments, supplied sequences of instantaneous two-dimensional gas fraction distributions with a high-resolution in space and time. This allows to derive from the data not only void fraction and bubble velocity profiles, but also bubble size distributions, bubble-size resolved radial gas fraction profiles as well as the axial evolution of these distributions. An interfacial surface reconstruction algorithm was developed in order to extract the extension of interfacial area from the wire-mesh sensor data. The sensors were upgraded to withstand parameters that are close to nuclear reactor conditions. Most of the experiments were performed for both air/water flow at ambient pressure and steam/water flow of up to 6.5 MPa at identical combinations of the gas and liquid superficial velocities. This offers excellent conditions for studying the influence of the fluid properties.

Published
2010

14. Experiments on upwards gas/liquid flow in vertical pipes

Author

Schütz, H., Pietruske, P., Manera, A., Carl, H., Beyer, M., Prasser, H.-M., Schütz, H., Pietruske, P., Manera, A., Carl, H., Beyer, M., and Prasser, H.-M.

Abstract

Two-phase flow experiments at vertical pipes are much suitable for studying the action of different constitutive relations characterizing the momentum exchange at the gas/liquid interface as well as the dynamic behaviour of the gas/liquid interface itself. The flow can be observed in its movement along the pipe and, in particular, within the shear field close to the pipe wall over a considerable vertical distance and, consequently, over a comparatively long time without the immediate separation of gas and liquid characteristic for horizontal flows. Wire-mesh sensors, which were the working horse in the described experiments, supplied sequences of instantaneous two-dimensional gas fraction distributions with a high-resolution in space and time. This allows to derive from the data not only void fraction and bubble velocity profiles, but also bubble size distributions, bubble-size resolved radial gas fraction profiles as well as the axial evolution of these distributions. An interfacial surface reconstruction algorithm was developed in order to extract the extension of interfacial area from the wire-mesh sensor data. The sensors were upgraded to withstand parameters that are close to nuclear reactor conditions. Most of the experiments were performed for both air/water flow at ambient pressure and steam/water flow of up to 6.5 MPa at identical combinations of the gas and liquid superficial velocities. This offers excellent conditions for studying the influence of the fluid properties.

Published
2010

15. Experiments on upwards gas/liquid flow in vertical pipes

Author

Schütz, H., Pietruske, P., Manera, A., Carl, H., Beyer, M., Prasser, H.-M., Schütz, H., Pietruske, P., Manera, A., Carl, H., Beyer, M., and Prasser, H.-M.

Abstract

Two-phase flow experiments at vertical pipes are much suitable for studying the action of different constitutive relations characterizing the momentum exchange at the gas/liquid interface as well as the dynamic behaviour of the gas/liquid interface itself. The flow can be observed in its movement along the pipe and, in particular, within the shear field close to the pipe wall over a considerable vertical distance and, consequently, over a comparatively long time without the immediate separation of gas and liquid characteristic for horizontal flows. Wire-mesh sensors, which were the working horse in the described experiments, supplied sequences of instantaneous two-dimensional gas fraction distributions with a high-resolution in space and time. This allows to derive from the data not only void fraction and bubble velocity profiles, but also bubble size distributions, bubble-size resolved radial gas fraction profiles as well as the axial evolution of these distributions. An interfacial surface reconstruction algorithm was developed in order to extract the extension of interfacial area from the wire-mesh sensor data. The sensors were upgraded to withstand parameters that are close to nuclear reactor conditions. Most of the experiments were performed for both air/water flow at ambient pressure and steam/water flow of up to 6.5 MPa at identical combinations of the gas and liquid superficial velocities. This offers excellent conditions for studying the influence of the fluid properties.

Published
2010

16. The new multifrequency electron cyclotron resonance heating system for ASDEX upgrade

Author

Wagner, D., Leuterer, F., Manini, A., Monaco, F., Münich, M., Ryter, F., d Schütz, H., Stober, J., Zohm, H., Franke, T., Danilov, I., Heidinger, R., Thumm, M., Gantenbein, G., Kasparek, W., Lechte, C., Litvak, A., Denisov, G., Tai, E., Popov, L., Nichiporenko, V., Myasnikov, V., Solyanova, E., Malygin, S., Meo, Fernando, Woskov, P., Wagner, D., Leuterer, F., Manini, A., Monaco, F., Münich, M., Ryter, F., d Schütz, H., Stober, J., Zohm, H., Franke, T., Danilov, I., Heidinger, R., Thumm, M., Gantenbein, G., Kasparek, W., Lechte, C., Litvak, A., Denisov, G., Tai, E., Popov, L., Nichiporenko, V., Myasnikov, V., Solyanova, E., Malygin, S., Meo, Fernando, and Woskov, P.

Published
2007

17. Experiments on upwards gas/liquid flow in vertical pipes

Author

Prasser, H.-M., Beyer, M., Carl, H., Manera, A., Schütz, H., Pietruske, P., Prasser, H.-M., Beyer, M., Carl, H., Manera, A., Schütz, H., and Pietruske, P.

Abstract

Two-phase flow experiments at vertical pipes are much suitable for studying the action of different constitutive relations characterizing the momentum exchange at the gas/liquid interface as well as the dynamic behaviour of the gas/liquid interface itself. The flow can be observed in its movement along the pipe and, in particular, within the shear field close to the pipe wall over a considerable vertical distance and, consequently, over a comparatively long time without the immediate separation of gas and liquid characteristic for horizontal flows. Wire-mesh sensors, which were the working horse in the described experiments, supplied sequences of instantaneous two-dimensional gas fraction distributions with a high-resolution in space and time. This allows to derive from the data not only void fraction and bubble velocity profiles, but also bubble size distributions, bubble-size resolved radial gas fraction profiles as well as the axial evolution of these distributions. An interfacial surface reconstruction algorithm was developed in order to extract the extension of interfacial area from the wire-mesh sensor data. The sensors were upgraded to withstand parameters that are close to nuclear reactor conditions. Most of the experiments were performed for both air/water flow at ambient pressure and steam/water flow of up to 6.5 MPa at identical combinations of the gas and liquid superficial velocities. This offers excellent conditions for studying the influence of the fluid properties.

Published
2007

18. The new multifrequency electron cyclotron resonance heating system for ASDEX upgrade

Author

Wagner, D., Leuterer, F., Manini, A., Monaco, F., Münich, M., Ryter, F., d Schütz, H., Stober, J., Zohm, H., Franke, T., Danilov, I., Heidinger, R., Thumm, M., Gantenbein, G., Kasparek, W., Lechte, C., Litvak, A., Denisov, G., Tai, E., Popov, L., Nichiporenko, V., Myasnikov, V., Solyanova, E., Malygin, S., Meo, Fernando, Woskov, P., Wagner, D., Leuterer, F., Manini, A., Monaco, F., Münich, M., Ryter, F., d Schütz, H., Stober, J., Zohm, H., Franke, T., Danilov, I., Heidinger, R., Thumm, M., Gantenbein, G., Kasparek, W., Lechte, C., Litvak, A., Denisov, G., Tai, E., Popov, L., Nichiporenko, V., Myasnikov, V., Solyanova, E., Malygin, S., Meo, Fernando, and Woskov, P.

Published
2007

19. First events from the CNGS neutrino beam detected in the OPERA experiment

Author

Acquafredda, R, Agafonova, N, Ambrosio, M, Anokhina, A, Aoki, S, Ariga, A, Arrabito, L, Autiero, D, Badertscher, A, Baussan, E, Bergnoli, A, Greggio, F, Besnier, M, Beyer, M, Bondil Blin, S, Borer, K, Boucrot, J, Boyarkin, V, Bozza, C, Brugnera, R, Buontempo, S, Caffari, Y, Campagne, J, Carlus, B, Carrara, E, Cazes, A, Chaussard, L, Chernyavsky, M, Chiarella, V, Chon Sen, N, Chukanov, A, Ciesielski, R, Consiglio, L, Cozzi, M, Corso, F, D'Ambrosio, N, Damet, J, Lellis, G, Déclais, Y, Descombes, T, Serio, M, Capua, F, Ferdinando, D, Giovanni, A, Marco, N, Troia, C, Dmitrievski, S, Dracos, M, Duchesneau, D, Dulach, B, Dusini, S, Ebert, J, Enikeev, R, Ereditato, A, Esposito, L, Fanin, C, Favier, J, Felici, G, Ferber, T, Fournier, L, Franceschi, A, Frekers, D, Fukuda, T, Fukushima, C, Galkin, V, Gallet, R, Garfagnini, A, Gaudiot, G, Giacomelli, G, Giarmana, O, Giorgini, M, Girard, L, Girerd, C, Goellnitz, C, Goldberg, J, Gornoushkin, Y, Grella, G, Grianti, F, Guerin, C, Guler, M, Gustavino, C, Hagner, C, Hamane, T, Hara, T, Hauger, M, Hess, M, Hoshino, K, Ieva, M, Incurvati, M, Jakovcic, K, Csathy, J, Janutta, B, Jollet, C, Juget, F, Kazuyama, M, Kim, S, Kimura, M, Knuesel, J, Kodama, K, Kolev, D, Komatsu, M, Kose, U, Krasnoperov, A, Kreslo, I, Krumstein, Z, Laktineh, I, Taille, C, Flour, T, Lieunard, S, Ljubicic, A, Longhin, A, Malgin, A, Manai, K, Mandrioli, G, Mantello, U, Marotta, A, Marteau, J, Martin Chassard, G, Matveev, V, Messina, M, Meyer, L, Micanovic, S, Migliozzi, P, Miyamoto, S, Monacelli, P, Monteiro, I, Morishima, K, Moser, U, Muciaccia, M, Mugnier, P, Naganawa, N, Nakamura, M, Nakano, T, Napolitano, T, Natsume, M, Niwa, K, Nonoyama, Y, Nozdrin, A, Ogawa, S, Olchevski, A, Orlandi, D, Ossetski, D, Paoloni, A, Park, B, Park, I, Pastore, A, Patrizii, L, Pellegrino, L, Pessard, H, Pilipenko, V, Pistillo, C, Polukhina, N, Pozzato, M, Pretzl, K, Publichenko, P, Raux, L, Repellin, J, Roganova, T, Romano, G, Rosa, G, Rubbia, A, Ryasny, V, Ryazhskaya, O, Ryzhikov, D, Sadovski, A, Sanelli, C, Sato, O, Sato, Y, Saveliev, V, Savvinov, N, Sazhina, G, Schembri, A, Parzefall, W, Schroeder, H, Schütz, H, Lavina, L, Sewing, J, Shibuya, H, Simone, S, Sioli, M, Sirignano, C, Sirri, G, Song, J, Spaeti, R, Spinetti, M, Stanco, L, Starkov, N, Stipcevic, M, Strolin, P, Sugonyaev, V, Takahashi, S, Tereschenko, V, Terranova, F, Tezuka, I, Tioukov, V, Tikhomirov, I, Tolun, P, Toshito, T, Tsarev, V, Tsenov, R, Ugolino, U, Ushida, N, Beek, G, Verguilov, V, Vilain, P, Votano, L, Vuilleumier, J, Waelchli, T, Waldi, R, Weber, M, Wilquet, G, Wonsak, B, Wurth, R, Wurtz, J, Yakushev, V, Yoon, C, Zaitsev, Y, Zamboni, I, Zimmermann, R, Greggio, FB, Campagne, JE, Corso, FD, Lellis, GD, Serio, MD, Capua, FD, Ferdinando, DD, Giovanni, AD, Marco, ND, Troia, CD, Esposito, LS, Galkin, VI, Galkin, VA, Csathy, JJ, Kim, SH, Taille, CdL, Flour, TL, Muciaccia, MT, Park, BD, Park, IG, Repellin, JP, Parzefall, WS, Schütz, HU, Lavina, LS, Song, JS, Beek, GV, Vuilleumier, JL, Yoon, CS, Zimmermann, R., TERRANOVA, FRANCESCO, Acquafredda, R, Agafonova, N, Ambrosio, M, Anokhina, A, Aoki, S, Ariga, A, Arrabito, L, Autiero, D, Badertscher, A, Baussan, E, Bergnoli, A, Greggio, F, Besnier, M, Beyer, M, Bondil Blin, S, Borer, K, Boucrot, J, Boyarkin, V, Bozza, C, Brugnera, R, Buontempo, S, Caffari, Y, Campagne, J, Carlus, B, Carrara, E, Cazes, A, Chaussard, L, Chernyavsky, M, Chiarella, V, Chon Sen, N, Chukanov, A, Ciesielski, R, Consiglio, L, Cozzi, M, Corso, F, D'Ambrosio, N, Damet, J, Lellis, G, Déclais, Y, Descombes, T, Serio, M, Capua, F, Ferdinando, D, Giovanni, A, Marco, N, Troia, C, Dmitrievski, S, Dracos, M, Duchesneau, D, Dulach, B, Dusini, S, Ebert, J, Enikeev, R, Ereditato, A, Esposito, L, Fanin, C, Favier, J, Felici, G, Ferber, T, Fournier, L, Franceschi, A, Frekers, D, Fukuda, T, Fukushima, C, Galkin, V, Gallet, R, Garfagnini, A, Gaudiot, G, Giacomelli, G, Giarmana, O, Giorgini, M, Girard, L, Girerd, C, Goellnitz, C, Goldberg, J, Gornoushkin, Y, Grella, G, Grianti, F, Guerin, C, Guler, M, Gustavino, C, Hagner, C, Hamane, T, Hara, T, Hauger, M, Hess, M, Hoshino, K, Ieva, M, Incurvati, M, Jakovcic, K, Csathy, J, Janutta, B, Jollet, C, Juget, F, Kazuyama, M, Kim, S, Kimura, M, Knuesel, J, Kodama, K, Kolev, D, Komatsu, M, Kose, U, Krasnoperov, A, Kreslo, I, Krumstein, Z, Laktineh, I, Taille, C, Flour, T, Lieunard, S, Ljubicic, A, Longhin, A, Malgin, A, Manai, K, Mandrioli, G, Mantello, U, Marotta, A, Marteau, J, Martin Chassard, G, Matveev, V, Messina, M, Meyer, L, Micanovic, S, Migliozzi, P, Miyamoto, S, Monacelli, P, Monteiro, I, Morishima, K, Moser, U, Muciaccia, M, Mugnier, P, Naganawa, N, Nakamura, M, Nakano, T, Napolitano, T, Natsume, M, Niwa, K, Nonoyama, Y, Nozdrin, A, Ogawa, S, Olchevski, A, Orlandi, D, Ossetski, D, Paoloni, A, Park, B, Park, I, Pastore, A, Patrizii, L, Pellegrino, L, Pessard, H, Pilipenko, V, Pistillo, C, Polukhina, N, Pozzato, M, Pretzl, K, Publichenko, P, Raux, L, Repellin, J, Roganova, T, Romano, G, Rosa, G, Rubbia, A, Ryasny, V, Ryazhskaya, O, Ryzhikov, D, Sadovski, A, Sanelli, C, Sato, O, Sato, Y, Saveliev, V, Savvinov, N, Sazhina, G, Schembri, A, Parzefall, W, Schroeder, H, Schütz, H, Lavina, L, Sewing, J, Shibuya, H, Simone, S, Sioli, M, Sirignano, C, Sirri, G, Song, J, Spaeti, R, Spinetti, M, Stanco, L, Starkov, N, Stipcevic, M, Strolin, P, Sugonyaev, V, Takahashi, S, Tereschenko, V, Terranova, F, Tezuka, I, Tioukov, V, Tikhomirov, I, Tolun, P, Toshito, T, Tsarev, V, Tsenov, R, Ugolino, U, Ushida, N, Beek, G, Verguilov, V, Vilain, P, Votano, L, Vuilleumier, J, Waelchli, T, Waldi, R, Weber, M, Wilquet, G, Wonsak, B, Wurth, R, Wurtz, J, Yakushev, V, Yoon, C, Zaitsev, Y, Zamboni, I, Zimmermann, R, Greggio, FB, Campagne, JE, Corso, FD, Lellis, GD, Serio, MD, Capua, FD, Ferdinando, DD, Giovanni, AD, Marco, ND, Troia, CD, Esposito, LS, Galkin, VI, Galkin, VA, Csathy, JJ, Kim, SH, Taille, CdL, Flour, TL, Muciaccia, MT, Park, BD, Park, IG, Repellin, JP, Parzefall, WS, Schütz, HU, Lavina, LS, Song, JS, Beek, GV, Vuilleumier, JL, Yoon, CS, Zimmermann, R., and TERRANOVA, FRANCESCO

Abstract

The OPERA neutrino detector at the underground Gran Sasso Laboratory (LNGS) was designed to perform the first detection of neutrino oscillations in appearance mode, through the study of nu_mu --> nu_tau oscillations. The apparatus consists of a lead/emulsion-film target complemented by electronic detectors. It is placed in the high-energy, long-baseline CERN to LNGS beam (CNGS) 730 km away from the neutrino source. In August 2006, a first run with CNGS neutrinos was successfully conducted. A first sample of neutrino events was collected, statistically consistent with the integrated beam intensity. After a brief description of the beam and of the various sub-detectors, we report on the achievement of this milestone, presenting the first data and some analysis results.

Published
2006

23. Jehova Hoc Secundante! & Gratioso Amplissimae Facultatis Iuridicae indultu, ac consensu benevolo, Dissertationem Iuris Publici, Varias Auctorum Sententias, De Statu Seu Forma S.R. Imperii Exhibentem, In Auditorio Maiori d. VIII May, Anno MDCXCV. publicae Eruditorum censurae subiiciet, Praeses Joachimus Henricus Sibrand, Rostochiensis, U.I. Doctorandus. Respondente Hans Albrecht Gutzmer/ Rostochiens.

Author

C. A. G. M., Lütkemann, Timotheus, Barnstorff, Johannes, Schütz, H. A., Willebrand, Albertus, M. J. F., Sibrand, Joachim Heinrich, Gutzmer, Hans Albrecht, C. A. G. M., Lütkemann, Timotheus, Barnstorff, Johannes, Schütz, H. A., Willebrand, Albertus, M. J. F., Sibrand, Joachim Heinrich, and Gutzmer, Hans Albrecht

Abstract

Alternativer Fingerprint (Blatt mit Widmungsgedichten nach dem Titelblatt eingebunden): n.t. 1.us adnt grse 3 1695R, Schlüsselseiten aus dem Exemplar der BSB München: 4 Diss. 129

24. Jehova Hoc Secundante! & Gratioso Amplissimae Facultatis Iuridicae indultu, ac consensu benevolo, Dissertationem Iuris Publici, Varias Auctorum Sententias, De Statu Seu Forma S.R. Imperii Exhibentem, In Auditorio Maiori d. VIII May, Anno MDCXCV. publicae Eruditorum censurae subiiciet, Praeses Joachimus Henricus Sibrand, Rostochiensis, U.I. Doctorandus. Respondente Hans Albrecht Gutzmer/ Rostochiens.

Author

C. A. G. M., Lütkemann, Timotheus, Barnstorff, Johannes, Schütz, H. A., Willebrand, Albertus, M. J. F., Sibrand, Joachim Heinrich, Gutzmer, Hans Albrecht, C. A. G. M., Lütkemann, Timotheus, Barnstorff, Johannes, Schütz, H. A., Willebrand, Albertus, M. J. F., Sibrand, Joachim Heinrich, and Gutzmer, Hans Albrecht

Abstract

Alternativer Fingerprint (Blatt mit Widmungsgedichten nach dem Titelblatt eingebunden): n.t. 1.us adnt grse 3 1695R, Schlüsselseiten aus dem Exemplar der BSB München: 4 Diss. 129

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