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9 results on '"Soldani, E."'

1. In vitro characterisation of SARS-CoV-2 and susceptibility of domestic ferrets (Mustela putorius furo)

Author

Marsh, GA, McAuley, AJ, Brown, S, Pharo, EA, Crameri, S, Au, GG, Baker, ML, Barr, JA, Bergfeld, J, Bruce, MP, Burkett, K, Durr, PA, Holmes, C, Izzard, L, Layton, R, Lowther, S, Neave, MJ, Poole, T, Riddell, S-J, Rowe, B, Soldani, E, Stevens, V, Suen, WW, Sundaramoorthy, V, Tachedjian, M, Todd, S, Trinidad, L, Williams, SM, Druce, JD, Drew, TW, Vasan, SS, Marsh, GA, McAuley, AJ, Brown, S, Pharo, EA, Crameri, S, Au, GG, Baker, ML, Barr, JA, Bergfeld, J, Bruce, MP, Burkett, K, Durr, PA, Holmes, C, Izzard, L, Layton, R, Lowther, S, Neave, MJ, Poole, T, Riddell, S-J, Rowe, B, Soldani, E, Stevens, V, Suen, WW, Sundaramoorthy, V, Tachedjian, M, Todd, S, Trinidad, L, Williams, SM, Druce, JD, Drew, TW, and Vasan, SS

Abstract

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is an emerging virus that has caused significant human morbidity and mortality since its detection in late 2019. With the rapid emergence has come an unprecedented programme of vaccine development with at least 300 candidates under development. Ferrets have proven to be an appropriate animal model for testing safety and efficacy of SARS-CoV-2 vaccines due to quantifiable virus shedding in nasal washes and oral swabs. Here, we outline our efforts early in the SARS-CoV-2 outbreak to propagate and characterize an Australian isolate of the virus in vitro and in an ex vivo model of human airway epithelium, as well as to demonstrate the susceptibility of domestic ferrets (Mustela putorius furo) to SARS-CoV-2 infection following intranasal challenge.

Published
2022

2. Characterisation and natural progression of SARS-CoV-2 infection in ferrets

Author

Au, GG, Marsh, GA, McAuley, AJ, Lowther, S, Trinidad, L, Edwards, S, Todd, S, Barr, J, Bruce, MP, Poole, TB, Brown, S, Layton, R, Riddell, S, Rowe, B, Soldani, E, Suen, WW, Bergfeld, J, Bingham, J, Payne, J, Durr, PA, Drew, TW, Vasan, SS, Au, GG, Marsh, GA, McAuley, AJ, Lowther, S, Trinidad, L, Edwards, S, Todd, S, Barr, J, Bruce, MP, Poole, TB, Brown, S, Layton, R, Riddell, S, Rowe, B, Soldani, E, Suen, WW, Bergfeld, J, Bingham, J, Payne, J, Durr, PA, Drew, TW, and Vasan, SS

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the infectious disease COVID-19, which has rapidly become an international pandemic with significant impact on healthcare systems and the global economy. To assist antiviral therapy and vaccine development efforts, we performed a natural history/time course study of SARS-CoV-2 infection in ferrets to characterise and assess the suitability of this animal model. Ten ferrets of each sex were challenged intranasally with 4.64 × 104 TCID50 of SARS-CoV-2 isolate Australia/VIC01/2020 and monitored for clinical disease signs, viral shedding, and tissues collected post-mortem for histopathological and virological assessment at set intervals. We found that SARS-CoV-2 replicated in the upper respiratory tract of ferrets with consistent viral shedding in nasal wash samples and oral swab samples up until day 9. Infectious SARS-CoV-2 was recovered from nasal washes, oral swabs, nasal turbinates, pharynx, and olfactory bulb samples within 3-7 days post-challenge; however, only viral RNA was detected by qRT-PCR in samples collected from the trachea, lung, and parts of the gastrointestinal tract. Viral antigen was seen exclusively in nasal epithelium and associated sloughed cells and draining lymph nodes upon immunohistochemical staining. Due to the absence of clinical signs after viral challenge, our ferret model is appropriate for studying asymptomatic SARS-CoV-2 infections and most suitable for use in vaccine efficacy studies.

Published
2022

3. In vitro characterisation of SARS-CoV-2 and susceptibility of domestic ferrets (Mustela putorius furo)

Author

Marsh, GA, McAuley, AJ, Brown, S, Pharo, EA, Crameri, S, Au, GG, Baker, ML, Barr, JA, Bergfeld, J, Bruce, MP, Burkett, K, Durr, PA, Holmes, C, Izzard, L, Layton, R, Lowther, S, Neave, MJ, Poole, T, Riddell, SJ, Rowe, B, Soldani, E, Stevens, V, Suen, WW, Sundaramoorthy, Vinod, Tachedjian, M, Todd, S, Trinidad, L, Williams, SM, Druce, JD, Drew, TW, Vasan, SS, Marsh, GA, McAuley, AJ, Brown, S, Pharo, EA, Crameri, S, Au, GG, Baker, ML, Barr, JA, Bergfeld, J, Bruce, MP, Burkett, K, Durr, PA, Holmes, C, Izzard, L, Layton, R, Lowther, S, Neave, MJ, Poole, T, Riddell, SJ, Rowe, B, Soldani, E, Stevens, V, Suen, WW, Sundaramoorthy, Vinod, Tachedjian, M, Todd, S, Trinidad, L, Williams, SM, Druce, JD, Drew, TW, and Vasan, SS

Published
2021

4. Interstrip Capacitances of the Readout Board used in Large Triple-GEM Detectors for the CMS Muon Upgrade

Author

Abbas, M., Abbrescia, M., Abdalla, H., Abdelalim, A., AbuZeid, S., Agapitos, A., Ahmad, A., Ahmed, A., Ahmed, W., Aimè, C., Aruta, C., Asghar, I., Aspell, P., Avila, C., Babbar, J., Ban, Y., Band, R., Bansal, S., Benussi, L., Bhatnagar, V., Bianco, M., Bianco, S., Black, K., Borgonovi, L., Bouhali, O., Braghieri, A., Braibant, S., Butalla, S., Calzaferri, S., Caponero, M., Cassese, F., Cavallo, N., Chauhan, S., Colaleo, A., Collins, J., Garcia, A. Conde, Dalchenko, M., De Iorio, A., De Lentdecker, G., Olio, D. Dell, De Robertis, G., Dharmaratna, W., Dildick, S., Dorney, B., Erbacher, R., Fabozzi, F., Fallavollita, F., Ferraro, A., Fiorina, D., Fontanesi, E., Franco, M., Galloni, C., Giacomelli, P., Gigli, S., Gilmore, J., Gola, M., Gruchala, M., Gutierrez, A., Hadjiiska, R., Hakkarainen, T., Hauser, J., Hoepfner, K., Hohlmann, M., Hoorani, H., Huang, T., Iaydjiev, P., Irshad, A., Iorio, A., Ivone, F., Jaramillo, J., Jeong, D., Jha, V., Juodagalvis, A., Juska, E., Kailasapathy, B., Kamon, T., Karchin, P., Kaur, A., Kaur, H., Keller, H., Kim, H., Kim, J., Kumar, A., Kumar, S., Kumawat, H., Lacalamita, N., Lee, J. S. H., Levin, A., Li, Q., Licciulli, F., Lista, L., Liyanage, K., Loddo, F., Lohan, M., Luhach, M., Maggi, M., Maghrbi, Y., Majumdar, N., Malagalage, K., Malhotra, S., Martiradonna, S., Mccoll, N., McLean, C., Merlin, J., Misheva, M., Mishra, D., Mocellin, G., Moureaux, L., Muhammad, A., Muhammad, S., Mukhopadhyay, S., Naimuddin, M., Netrakanti, P., Nuzzo, S., Oliveira, R., Pant, L., Paolucci, P., Park, I. C., Passamonti, L., Passeggio, G., Peck, A., Perera, N., Petre, L., Petrow, H., Piccolo, D., Pierluigi, D., Raffone, G., Rahmani, M., Ramirez, F., Ranieri, A., Rashevski, G., Ressegotti, M., Riccardi, C., Rodozov, M., Romano, E., Roskas, C., Rossi, B., Rout, P., Roy, D., Ruiz, J. D., Russo, A., Safonov, A., Saltzberg, D., Saviano, G., Shah, A., Sharma, A., Sharma, R., Shopova, M., Simone, F., Singh, J., Soldani, E., Sonnadara, U., Starling, E., Stone, B., Sturdy, J., Sultanov, G., Szillasi, Z., Teague, D., Teyssier, D., Tuuva, T., Tytgat, M., Vanegas, I. Vai N., Venditti, R., Verwilligen, P., Vetens, W., Virdi, A., Vitulo, P., Wajid, A., Wang, D., Wang, K., Watson, I. J., Weatherwax, J., Wickramage, N., Wickramarathna, D. D. C., Yang, Y., Yang, U., Yongho, J., Yoon, I., You, Z., Yu, I., Zaleski, S., Abbas, M., Abbrescia, M., Abdalla, H., Abdelalim, A., AbuZeid, S., Agapitos, A., Ahmad, A., Ahmed, A., Ahmed, W., Aimè, C., Aruta, C., Asghar, I., Aspell, P., Avila, C., Babbar, J., Ban, Y., Band, R., Bansal, S., Benussi, L., Bhatnagar, V., Bianco, M., Bianco, S., Black, K., Borgonovi, L., Bouhali, O., Braghieri, A., Braibant, S., Butalla, S., Calzaferri, S., Caponero, M., Cassese, F., Cavallo, N., Chauhan, S., Colaleo, A., Collins, J., Garcia, A. Conde, Dalchenko, M., De Iorio, A., De Lentdecker, G., Olio, D. Dell, De Robertis, G., Dharmaratna, W., Dildick, S., Dorney, B., Erbacher, R., Fabozzi, F., Fallavollita, F., Ferraro, A., Fiorina, D., Fontanesi, E., Franco, M., Galloni, C., Giacomelli, P., Gigli, S., Gilmore, J., Gola, M., Gruchala, M., Gutierrez, A., Hadjiiska, R., Hakkarainen, T., Hauser, J., Hoepfner, K., Hohlmann, M., Hoorani, H., Huang, T., Iaydjiev, P., Irshad, A., Iorio, A., Ivone, F., Jaramillo, J., Jeong, D., Jha, V., Juodagalvis, A., Juska, E., Kailasapathy, B., Kamon, T., Karchin, P., Kaur, A., Kaur, H., Keller, H., Kim, H., Kim, J., Kumar, A., Kumar, S., Kumawat, H., Lacalamita, N., Lee, J. S. H., Levin, A., Li, Q., Licciulli, F., Lista, L., Liyanage, K., Loddo, F., Lohan, M., Luhach, M., Maggi, M., Maghrbi, Y., Majumdar, N., Malagalage, K., Malhotra, S., Martiradonna, S., Mccoll, N., McLean, C., Merlin, J., Misheva, M., Mishra, D., Mocellin, G., Moureaux, L., Muhammad, A., Muhammad, S., Mukhopadhyay, S., Naimuddin, M., Netrakanti, P., Nuzzo, S., Oliveira, R., Pant, L., Paolucci, P., Park, I. C., Passamonti, L., Passeggio, G., Peck, A., Perera, N., Petre, L., Petrow, H., Piccolo, D., Pierluigi, D., Raffone, G., Rahmani, M., Ramirez, F., Ranieri, A., Rashevski, G., Ressegotti, M., Riccardi, C., Rodozov, M., Romano, E., Roskas, C., Rossi, B., Rout, P., Roy, D., Ruiz, J. D., Russo, A., Safonov, A., Saltzberg, D., Saviano, G., Shah, A., Sharma, A., Sharma, R., Shopova, M., Simone, F., Singh, J., Soldani, E., Sonnadara, U., Starling, E., Stone, B., Sturdy, J., Sultanov, G., Szillasi, Z., Teague, D., Teyssier, D., Tuuva, T., Tytgat, M., Vanegas, I. Vai N., Venditti, R., Verwilligen, P., Vetens, W., Virdi, A., Vitulo, P., Wajid, A., Wang, D., Wang, K., Watson, I. J., Weatherwax, J., Wickramage, N., Wickramarathna, D. D. C., Yang, Y., Yang, U., Yongho, J., Yoon, I., You, Z., Yu, I., and Zaleski, S.

Abstract

We present analytical calculations, Finite Element Analysis modeling, and physical measurements of the interstrip capacitances for different potential strip geometries and dimensions of the readout boards for the GE2/1 triple-Gas Electron Multiplier detector in the CMS muon system upgrade. The main goal of the study is to find configurations that minimize the interstrip capacitances and consequently maximize the signal-to-noise ratio for the detector. We find agreement at the 1.5--4.8% level between the two methods of calculations and on the average at the 17% level between calculations and measurements. A configuration with halved strip lengths and doubled strip widths results in a measured 27--29% reduction over the original configuration while leaving the total number of strips unchanged. We have now adopted this design modification for all eight module types of the GE2/1 detector and will produce the final detector with this new strip design., Comment: 22 pages, 14 figures

Published
2020
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5. A Cylindrical GEM Inner Tracker for the BESIII experiment at IHEP

Author

Farinelli, R., Alexeev, M., Amoroso, A., Bianchi, F., Bertani, M., Bettoni, D., Canale, N., Calcaterra, A., Carassiti, V., Cerioni, S., Chai, J., Chiozzi, S., Cibinetto, G., Ramusino, A. Cotta, Cossio, F., De Mori, F., Destefanis, M., Edisher, T., Evangelisti, F., Fava, L., Felici, G., Fioravanti, E., Garzia, I., Gatta, M., Greco, M., Jing, D., Lavezzi, L., Leng, C., Li, H., Maggiora, M., Malaguti, R., Marcello, S., Melchiorri, M., Mezzadri, G., Morello, G., Pacetti, S., Patteri, P., Pellegrino, J., Rivetti, A., Rolo, M. D., Savrie, M., Scodeggio, M., Soldani, E., Sosio, S., Spataro, S., Yang, L., Farinelli, R., Alexeev, M., Amoroso, A., Bianchi, F., Bertani, M., Bettoni, D., Canale, N., Calcaterra, A., Carassiti, V., Cerioni, S., Chai, J., Chiozzi, S., Cibinetto, G., Ramusino, A. Cotta, Cossio, F., De Mori, F., Destefanis, M., Edisher, T., Evangelisti, F., Fava, L., Felici, G., Fioravanti, E., Garzia, I., Gatta, M., Greco, M., Jing, D., Lavezzi, L., Leng, C., Li, H., Maggiora, M., Malaguti, R., Marcello, S., Melchiorri, M., Mezzadri, G., Morello, G., Pacetti, S., Patteri, P., Pellegrino, J., Rivetti, A., Rolo, M. D., Savrie, M., Scodeggio, M., Soldani, E., Sosio, S., Spataro, S., and Yang, L.

Abstract

The Beijing Electron Spectrometer III (BESIII) is a multipurpose detector that collects data provided by the collision in the Beijing Electron Positron Collider II (BEPCII), hosted at the Institute of High Energy Physics of Beijing. Since the beginning of its operation, BESIII has collected the world largest sample of J/{\psi} and {\psi}(2s). Due to the increase of the luminosity up to its nominal value of 10^33 cm-2 s-1 and aging effect, the MDC decreases its efficiency in the first layers up to 35% with respect to the value in 2014. Since BESIII has to take data up to 2022 with the chance to continue up to 2027, the Italian collaboration proposed to replace the inner part of the MDC with three independent layers of Cylindrical triple-GEM (CGEM). The CGEM-IT project will deploy several new features and innovation with respect the other current GEM based detector: the {\mu}TPC and analog readout, with time and charge measurements will allow to reach the 130 {\mu}m spatial resolution in 1 T magnetic field requested by the BESIII collaboration. In this proceeding, an update of the status of the project will be presented, with a particular focus on the results with planar and cylindrical prototypes with test beams data. These results are beyond the state of the art for GEM technology in magnetic field.

Published
2018

6. The new cylindrical GEM inner tracker of BESIII

Author

Lavezzi, L., Alexeev, M., Amoroso, A., Ferroli, R. Baldini, Bertani, M., Bettoni, D., Bianchi, F., Calcaterra, A., Canale, N., Capodiferro, M., Carassiti, V., Cerioni, S., Chai, JY., Chiozzi, S., Cibinetto, G., Cossio, F., Ramusino, A. Cotta, De Mori, F., Destefanis, M., Dong, J., Evangelisti, F., Farinelli, R., Fava, L., Felici, G., Fioravanti, E., Garzia, I., Gatta, M., Greco, M., Leng, CY., Li, H., Maggiora, M., Malaguti, R., Marcello, S., Melchiorri, M., Mezzadri, G., Mignone, M., Morello, G., Pacetti, S., Patteri, P., Pellegrino, J., Pelosi, A., Rivetti, A., Rolo, M. D., Savrie', M., Scodeggio, M., Soldani, E., Sosio, S., Spataro, S., Tskhadadze, E., Verma, S., Wheadon, R., Yan, L., Lavezzi, L., Alexeev, M., Amoroso, A., Ferroli, R. Baldini, Bertani, M., Bettoni, D., Bianchi, F., Calcaterra, A., Canale, N., Capodiferro, M., Carassiti, V., Cerioni, S., Chai, JY., Chiozzi, S., Cibinetto, G., Cossio, F., Ramusino, A. Cotta, De Mori, F., Destefanis, M., Dong, J., Evangelisti, F., Farinelli, R., Fava, L., Felici, G., Fioravanti, E., Garzia, I., Gatta, M., Greco, M., Leng, CY., Li, H., Maggiora, M., Malaguti, R., Marcello, S., Melchiorri, M., Mezzadri, G., Mignone, M., Morello, G., Pacetti, S., Patteri, P., Pellegrino, J., Pelosi, A., Rivetti, A., Rolo, M. D., Savrie', M., Scodeggio, M., Soldani, E., Sosio, S., Spataro, S., Tskhadadze, E., Verma, S., Wheadon, R., and Yan, L.

Abstract

The Cylindrical GEM-Inner Tracker (CGEM-IT) is the upgrade of the internal tracking system of the BESIII experiment. It consists of three layers of cylindrically-shaped triple GEMs, with important innovations with respect to the existing GEM detectors, in order to achieve the best performance with the lowest material budget. It will be the first cylindrical GEM running with analog readout inside a 1T magnetic field. The simultaneous measurement of both the deposited charge and the signal time will permit to use a combination of two algorithms to evaluate the spatial position of the charged tracks inside the CGEM-IT: the charge centroid and the micro time projection chamber modes. They are complementary and can cope with the asymmetry of the electron avalanche when running in magnetic field and with non-orthogonal incident tracks. To evaluate the behavior under different working settings, both planar chambers and the first cylindrical prototype have been tested during various test beams at CERN with 150 GeV/c muons and pions. This paper reports the results obtained with the two reconstruction methods and a comparison between the planar and cylindrical chambers., Comment: Proceedings for "Particles and Nuclei International Conference 2017" (PANIC17) Conference, 1-5 September 2017, Beijing, China (prepared for submission to International Journal of Modern Physics: Conference Series)

Published
2018
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7. Test beam results of a Cylindrical GEM detector for the BESIII experiment

Author

Mezzadri, G., Alexeev, M., Amoroso, A., Ferroli, R. Baldini, Bertani, M., Bettoni, D., Bianchi, F., Calcaterra, A., Canale, N., Capodiferro, M., Carassiti, V., Cerioni, S., Chai, JY., Chiozzi, S., Cibinetto, G., Cossio, F., Ramusino, A. Cotta, De Mori, F., Destefanis, M., Dong, J., Evangelisti, F., Farinelli, R., Fava, L., Felici, G., Fioravanti, E., Garzia, I., Gatta, M., Greco, M., Lavezzi, L., Leng, CY., Li, H., Maggiora, M., Malaguti, R., Mangoni, A., Marcello, S., Melchiorri, M., Mignone, M., Morello, G., Pacetti, S., Patteri, P., Pellegrino, J., Pelosi, A., Rivetti, A., Rolo, M. D., Savrié, M., Scodeggio, M., Soldani, E., Sosio, S., Spataro, S., Tskhadadze, E., Verma, S., Wheadon, R., Yan, L., Mezzadri, G., Alexeev, M., Amoroso, A., Ferroli, R. Baldini, Bertani, M., Bettoni, D., Bianchi, F., Calcaterra, A., Canale, N., Capodiferro, M., Carassiti, V., Cerioni, S., Chai, JY., Chiozzi, S., Cibinetto, G., Cossio, F., Ramusino, A. Cotta, De Mori, F., Destefanis, M., Dong, J., Evangelisti, F., Farinelli, R., Fava, L., Felici, G., Fioravanti, E., Garzia, I., Gatta, M., Greco, M., Lavezzi, L., Leng, CY., Li, H., Maggiora, M., Malaguti, R., Mangoni, A., Marcello, S., Melchiorri, M., Mignone, M., Morello, G., Pacetti, S., Patteri, P., Pellegrino, J., Pelosi, A., Rivetti, A., Rolo, M. D., Savrié, M., Scodeggio, M., Soldani, E., Sosio, S., Spataro, S., Tskhadadze, E., Verma, S., Wheadon, R., and Yan, L.

Abstract

Gas detector are very light instrument used in high energy physics to measure the particle properties: position and momentum. Through high electric field is possible to use the Gas Electron Multiplier (GEM) technology to detect the charged particles and to exploit their properties to construct a large area detector, such as the new IT for BESIII. The state of the art in the GEM production allows to create very large area GEM foils (up to 50x100 $\mathrm{cm}^2$) and thanks to the small thickness of these foils is it possible to shape it to the desired form: a Cylindrical Gas Electron Multiplier (CGEM) is then proposed. The innovative construction technique based on Rohacell, a PMI foam, will give solidity to cathode and anode with a very low impact on material budget. The entire detector is sustained by Permaglass rings glued at the edges. These rings are used to assembly the CGEM, together with a dedicated Vertical Insertion System and moreover they host the On-Detector electronic. The anode has been improved w.r.t. the state of the art through a jagged readout that minimize the inter-strip capacitance. The mechanical challenge of this detector requires a precision of the entire geometry within few hundreds of microns in the whole area. In this contribution an overview of the construction technique, the validation of this technique through the realization of a CGEM, and its first tests will be presented. These activities are performed within the framework of the BESIIICGEM Project (645664), funded by the European Commission in the action H2020-RISE-MSCA-2014., Comment: 10 pages, 7 figures. Proceedings of 5th International Conference on Micro-Pattern Gas Detectors (MPGD2017), Philadelphia 22-26 May 2017

Published
2018

8. Results of the first user program on the HOmogeneous Thermal NEutron Source HOTNES (ENEA/INFN)

Author

Sperduti, Andrea, Angelone, M., Bedogni, R., Claps, G., Diociaiuti, E., Domingo, C., Donghia, R., Giovannella, S., Gomez-Ros, J. M., Irazola-Rosales, L., Loreti, S., Monti, V., Miscetti, S., Murtas, F., Pagano, G., Pillon, M., Pilotti, R., Pola, A., Romero-Exposito, M., Sanchez-Doblado, F., Sans-Planell, O., Scherillo, A., Soldani, E., Treccani, M., Pietropaolo, A., Sperduti, Andrea, Angelone, M., Bedogni, R., Claps, G., Diociaiuti, E., Domingo, C., Donghia, R., Giovannella, S., Gomez-Ros, J. M., Irazola-Rosales, L., Loreti, S., Monti, V., Miscetti, S., Murtas, F., Pagano, G., Pillon, M., Pilotti, R., Pola, A., Romero-Exposito, M., Sanchez-Doblado, F., Sans-Planell, O., Scherillo, A., Soldani, E., Treccani, M., and Pietropaolo, A.

Abstract

The HOmogeneous Thermal NEutron Source (HOTNES) is a new type of thermal neutron irradiation assembly developed by the ENEA-INFN collaboration. The facility is fully characterized in terms of neutron field and dosimetric quantities, by either computational and experimental methods. This paper reports the results of the first "HOTNES users program", carried out in 2016, and covering a variety of thermal neutron active detectors such as scintillators, solid-state, single crystal diamond and gaseous detectors.

Published
2017
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9. A custom readout electronics for the BESIII CGEM detector

Author

Rolo, M. Da Rocha, Alexeev, M., Amoroso, A., Ferroli, R. Baldini, Bertani, M., Bettoni, D., Bianchi, F., Bugalho, R., Calcaterra, A., Canale, N., Capodiferro, M., Carassiti, V., Cerioni, S., Chai, J. Y., Chiozzi, S., Cibinetto, G., Cossio, F., Ramusino, A. Cotta, De Mori, F., Destefanis, M., Di Francesco, A., Dong, J., Evangelisti, F., Farinelli, R., Fava, L., Felici, G., Fioravanti, E., Garzia, I., Gatta, M., Greco, M., Lavezzi, L., Leng, C. Y., Li, H., Maggiora, M., Malaguti, R., Marcello, S., Marcinievski, Pawel, Melchiorri, M., Mezzadri, G., Mignone, M., Morello, G., Pacetti, S., Patteri, P., Pellegrino, J., Pelosi, A., Rivetti, A., Savrie, M., Scodeggio, M., Soldani, E., Sosio, S., Spataro, S., Tskhadadze, E., Varela, J., Verma, S., Wheadon, R., Yan, L., Rolo, M. Da Rocha, Alexeev, M., Amoroso, A., Ferroli, R. Baldini, Bertani, M., Bettoni, D., Bianchi, F., Bugalho, R., Calcaterra, A., Canale, N., Capodiferro, M., Carassiti, V., Cerioni, S., Chai, J. Y., Chiozzi, S., Cibinetto, G., Cossio, F., Ramusino, A. Cotta, De Mori, F., Destefanis, M., Di Francesco, A., Dong, J., Evangelisti, F., Farinelli, R., Fava, L., Felici, G., Fioravanti, E., Garzia, I., Gatta, M., Greco, M., Lavezzi, L., Leng, C. Y., Li, H., Maggiora, M., Malaguti, R., Marcello, S., Marcinievski, Pawel, Melchiorri, M., Mezzadri, G., Mignone, M., Morello, G., Pacetti, S., Patteri, P., Pellegrino, J., Pelosi, A., Rivetti, A., Savrie, M., Scodeggio, M., Soldani, E., Sosio, S., Spataro, S., Tskhadadze, E., Varela, J., Verma, S., Wheadon, R., and Yan, L.

Abstract

For the upgrade of the inner tracker of the BESIII spectrometer, planned for 2018, a lightweight tracker based on an innovative Cylindrical Gas Electron Multiplier (CGEM) detector is now under development. The analogue readout of the CGEM enables the use of a charge centroid algorithm to improve the spatial resolution to better than 130 mu m while loosening the pitch strip to 650 mu m, which allows to reduce the total number of channels to about 10 000. The channels are readout by 160 dedicated integrated 64-channel front-end ASICs, providing a time and charge measurement and featuring a fully-digital output. The energy measurement is extracted either from the time-over-threshold (ToT) or the 10-bit digitisation of the peak amplitude of the signal. The time of the event is generated by quad-buffered low-power TDCs, allowing for rates in excess of 60 kHz per channel. The TDCs are based on analogue interpolation techniques and produce a time stamp (or two, if working in ToT mode) of the event with a time resolution better than 50 ps. The front-end noise, based on a CSA and a two-stage complex conjugated pole shapers, dominate the channel intrinsic time jitter, which is less than 5 ns r.m.s. The time information of the hit can be used to reconstruct the track path, operating the detector as a small TPC and hence improving the position resolution when the distribution of the cloud, due to large incident angle or magnetic field, is very broad. Event data is collected by an off-detector motherboard, where each GEM-ROC readout card handles 4 ASIC carrier FEBs (512 channels). Configuration upload and data readout between the off-detector electronics and the VME-based data collector cards are managed by bi-directional fibre optical links. This paper covers the design of a custom front-end electronics for the readout of the new inner tracker of the BESIII experiment, addressing the relevant design aspects of the detector electronics and the front-end ASIC for the CGEM readout

Published
2017
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