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1. Population modifiable risk factors associated with under-5 acute respiratory tract infections and diarrhoea in 25 countries in sub-Saharan Africa (2014-2021): an analysis of data from demographic and health surveys.

Author: Ahmed, KY, Dadi, AF, Kibret, GD, Bizuayehu, HM, Hassen, TA, Amsalu, E, Ketema, DB, Kassa, ZY, Bore, MG, Alebel, A, Alemu, AA, Shifa, JE, Leshargie, CT, Thapa, S, Omar, SH, Ross, AG, Ahmed, KY, Dadi, AF, Kibret, GD, Bizuayehu, HM, Hassen, TA, Amsalu, E, Ketema, DB, Kassa, ZY, Bore, MG, Alebel, A, Alemu, AA, Shifa, JE, Leshargie, CT, Thapa, S, Omar, SH, and Ross, AG
Abstract: BACKGROUND: Identifying the critical modifiable risk factors for acute respiratory tract infections (ARIs) and diarrhoea is crucial to reduce the burden of disease and mortality among children under 5 years of age in sub-Saharan Africa (SSA) and ultimately achieving the Sustainable Development Goals (SDGs). We investigated the modifiable risk factors of ARI and diarrhoea among children under five using nationally representative surveys. METHODS: We used the most recent demographic and health survey (DHS) data (2014-2021) from 25 SSA countries, encompassing a total of 253,167 children. Countries were selected based on the availability of recent datasets (e.g., DHS-VII or DHS-VIII) that represent the current socioeconomic situations. Generalised linear latent mixed models were used to compute odds ratios (ORs). Population attributable fractions (PAFs) were calculated using adjusted ORs and prevalence estimates for key modifiable risk factors among ARI and diarrhoeal cases. FINDINGS: This study involved 253,167 children, with a mean age of 28.7 (±17.3) months, and 50.5% were male. The highest PAFs for ARI were attributed to unclean cooking fuel (PAF = 15.7%; 95% CI: 8.1, 23.1), poor maternal education (PAF = 13.4%; 95% CI: 8.7, 18.5), delayed initiation of breastfeeding (PAF = 12.4%; 95% CI: 9.0, 15.3), and poor toilets (PAF = 8.5%; 95% CI: 4.7, 11.9). These four modifiable risk factors contributed to 41.5% (95% CI: 27.2, 52.9) of ARI cases in SSA. The largest PAFs of diarrhoea were observed for unclean cooking fuel (PAF = 17.3%; 95% CI: 13.5, 22.3), delayed initiation of breastfeeding (PAF = 9.2%; 95% CI: 7.5, 10.5), household poverty (PAF = 7.0%; 95% CI: 5.0, 9.1) and poor maternal education (PAF = 5.6%; 95% CI: 2.9, 8.8). These four modifiable risk factors contributed to 34.0% (95% CI: 26.2, 42.3) of cases of diarrhoea in SSA. INTERPRETATION: This cross-sectional study identified four modifiable risk factors for ARI and diarrhoea that should be a priority for policy
Published: 2024

2. Explainable hybrid word representations for sentiment analysis of financial news.

Author: Adhikari, S, Thapa, S, Naseem, U, Lu, HY, Bharathy, G, Prasad, M, Adhikari, S, Thapa, S, Naseem, U, Lu, HY, Bharathy, G, and Prasad, M
Abstract: Due to the increasing interest of people in the stock and financial market, the sentiment analysis of news and texts related to the sector is of utmost importance. This helps the potential investors in deciding what company to invest in and what are their long-term benefits. However, it is challenging to analyze the sentiments of texts related to the financial domain, given the enormous amount of information available. The existing approaches are unable to capture complex attributes of language such as word usage, including semantics and syntax throughout the context, and polysemy in the context. Further, these approaches failed to interpret the models' predictability, which is obscure to humans. Models' interpretability to justify the predictions has remained largely unexplored and has become important to engender users' trust in the predictions by providing insight into the model prediction. Accordingly, in this paper, we present an explainable hybrid word representation that first augments the data to address the class imbalance issue and then integrates three embeddings to involve polysemy in context, semantics, and syntax in a context. We then fed our proposed word representation to a convolutional neural network (CNN) with attention to capture the sentiment. The experimental results show that our model outperforms several baselines of both classic classifiers and combinations of various word embedding models in the sentiment analysis of financial news. The experimental results also show that the proposed model outperforms several baselines of word embeddings and contextual embeddings when they are separately fed to a neural network model. Further, we show the explainability of the proposed method by presenting the visualization results to explain the reason for a prediction in the sentiment analysis of financial news.
Published: 2023

3. International consensus statement on obstructive sleep apnea.

Author: Chang J.L., Goldberg A.N., Alt J.A., Ashbrook L., Auckley D., Ayappa I., Bakhtiar H., Barrera J.E., Bartley B.L., Billings M.E., Boon M.S., Bosschieter P., Braverman I., Brodie K., Cabrera-Muffly C., Caesar R., Cahali M.B., Cai Y., Cao M., Capasso R., Caples S.M., Chahine L.M., Chang C.P., Chang K.W., Chaudhary N., Cheong C.S.J., Chowdhuri S., Cistulli P.A., Claman D., Collen J., Coughlin K., Creamer J., Davis E.M., Dupuy-McCauley K.L., Durr M.L., Dutt M., Ali M.E., Elkassabany N.M., Epstein L.J., Fiala J.A., Freedman N., Gill K., Gillespie M.B., Golisch L., Gooneratne N., Gottlieb D.J., Green K.K., Gulati A., Gurubhagavatula I., Hayward N., Hoff P.T., Hoffmann O.M.G., Holfinger S.J., Hsia J., Huntley C., Huoh K.C., Huyett P., Inala S., Ishman S., Jella T.K., Jobanputra A.M., Johnson A.P., Junna M.R., Kado J.T., Kaffenberger T.M., Kapur V.K., Kezirian E.J., Khan M., Kirsch D.B., Kominsky A., Kryger M., Krystal A.D., Kushida C.A., Kuzniar T.J., Lam D.J., Lettieri C.J., Lim D.C., Lin H.-C., Liu S.Y.C., MacKay S.G., Magalang U.J., Malhotra A., Maurer J.T., May A.M., Mitchell R.B., Mokhlesi B., Mullins A.E., Nada E.M., Naik S., Nokes B., Olson M.D., Pack A.I., Pang E.B., Pang K.P., Patil S.P., de Perck E.V., Piccirillo J.F., Pien G.W., Piper A.J., Plawecki A., Quigg M., Ravesloot M.J.L., Redline S., Rotenberg B.W., Ryden A., Sarmiento K.F., Sbeih F., Schell A.E., Schmickl C.N., Schotland H.M., Schwab R.J., Seo J., Shah N., Shelgikar A.V., Shochat I., Soose R.J., Steele T.O., Stephens E., Stepnowsky C., Strohl K.P., Sutherland K., Suurna M.V., Thaler E., Thapa S., Vanderveken O.M., de Vries N., Weaver E.M., Weir I.D., Wolfe L.F., Woodson B.T., Won C.H.J., Xu J., Yalamanchi P., Yaremchuk K., Yeghiazarians Y., Yu J.L., Zeidler M., Rosen I.M., Chang J.L., Goldberg A.N., Alt J.A., Ashbrook L., Auckley D., Ayappa I., Bakhtiar H., Barrera J.E., Bartley B.L., Billings M.E., Boon M.S., Bosschieter P., Braverman I., Brodie K., Cabrera-Muffly C., Caesar R., Cahali M.B., Cai Y., Cao M., Capasso R., Caples S.M., Chahine L.M., Chang C.P., Chang K.W., Chaudhary N., Cheong C.S.J., Chowdhuri S., Cistulli P.A., Claman D., Collen J., Coughlin K., Creamer J., Davis E.M., Dupuy-McCauley K.L., Durr M.L., Dutt M., Ali M.E., Elkassabany N.M., Epstein L.J., Fiala J.A., Freedman N., Gill K., Gillespie M.B., Golisch L., Gooneratne N., Gottlieb D.J., Green K.K., Gulati A., Gurubhagavatula I., Hayward N., Hoff P.T., Hoffmann O.M.G., Holfinger S.J., Hsia J., Huntley C., Huoh K.C., Huyett P., Inala S., Ishman S., Jella T.K., Jobanputra A.M., Johnson A.P., Junna M.R., Kado J.T., Kaffenberger T.M., Kapur V.K., Kezirian E.J., Khan M., Kirsch D.B., Kominsky A., Kryger M., Krystal A.D., Kushida C.A., Kuzniar T.J., Lam D.J., Lettieri C.J., Lim D.C., Lin H.-C., Liu S.Y.C., MacKay S.G., Magalang U.J., Malhotra A., Maurer J.T., May A.M., Mitchell R.B., Mokhlesi B., Mullins A.E., Nada E.M., Naik S., Nokes B., Olson M.D., Pack A.I., Pang E.B., Pang K.P., Patil S.P., de Perck E.V., Piccirillo J.F., Pien G.W., Piper A.J., Plawecki A., Quigg M., Ravesloot M.J.L., Redline S., Rotenberg B.W., Ryden A., Sarmiento K.F., Sbeih F., Schell A.E., Schmickl C.N., Schotland H.M., Schwab R.J., Seo J., Shah N., Shelgikar A.V., Shochat I., Soose R.J., Steele T.O., Stephens E., Stepnowsky C., Strohl K.P., Sutherland K., Suurna M.V., Thaler E., Thapa S., Vanderveken O.M., de Vries N., Weaver E.M., Weir I.D., Wolfe L.F., Woodson B.T., Won C.H.J., Xu J., Yalamanchi P., Yaremchuk K., Yeghiazarians Y., Yu J.L., Zeidler M., and Rosen I.M.
Abstract: BACKGROUND: Evaluation and interpretation of the literature on obstructive sleep apnea is needed to consolidate and summarize key factors important for clinical management of the OSA adult patient. Toward this goal, an international collaborative of multidisciplinary experts in sleep apnea evaluation and treatment have produced the International Consensus statement on Obstructive Sleep Apnea (ICS:OSA). METHOD(S): Using previously defined methodology, focal topics in OSA were assigned as literature review (LR), evidence-based review (EBR), or evidence-based review with recommendations (EBR-R) formats. Each topic incorporated the available and relevant evidence which was summarized and graded on study quality. Each topic and section underwent iterative review and the ICS:OSA was created and reviewed by all authors for consensus. RESULT(S): The ICS:OSA addresses OSA syndrome definitions, pathophysiology, epidemiology, risk factors for disease, screening methods, diagnostic testing types, multiple treatment modalities, and effects of OSA and treatment on the multiple comorbidities. Specific focus on outcomes with positive airway pressure (PAP) and surgical treatments were evaluated. CONCLUSION(S): This review of the literature in OSA consolidates the available knowledge and identifies the limitations of the current evidence. This effort aims to highlight the basis of OSA evidence-based practice and identify future research needs. Knowledge gaps and opportunities for improvement include improving the metrics of OSA disease, determining the optimal OSA screening paradigms, developing strategies for PAP adherence and longitudinal care, enhancing selection of PAP alternatives and surgery, understanding health risk outcomes, and translating evidence into individualized approaches to therapy. This article is protected by copyright. All rights reserved.
Published: 2022

4. Women's attitude towards intimate partner violence and utilization of contraceptive methods and maternal health care services: an analysis of nationally representative cross-sectional surveys from four South Asian countries

Author: Shrestha, SK, Thapa, S, Vicendese, D, Erbas, B, Shrestha, SK, Thapa, S, Vicendese, D, and Erbas, B
Abstract: BACKGROUND: Intimate partner violence (IPV) adversely affects women's reproductive health outcomes but to what extent women's justification of IPV affects maternal health care service utilization is unexplored. METHODS: The secondary cross-sectional datasets from multiple indicator cluster surveys of Afghanistan, Bhutan, Nepal and Pakistan conducted between 2010 and 2015 were used. We used a generalized linear mixed model with random effects, at both cluster- and country-level, to determine the odds ratio of maternal health service utilization at the regional level and a multivariable logistic regression model adjusting for complex survey design at the country level. Interaction between women's justification of IPV and residential location, and linear trend in the utilization of maternal health care services associated with increasing levels of women's justification of IPV, were examined using the Likelihood Ratio Test (LRT). RESULTS: A total of 26,029 women aged 15-49 years, living with their partners and had a pregnancy outcome 2 years prior to the survey were included. Women justifying IPV were less likely to utilize contraceptive methods (aOR) = 0.86, 95% CI 0.84, 0.88), at-least one Antenatal Care (ANC) visit (aOR = 0.80, 95% CI 0.72, 0.88), four or more ANC services (aOR = 0.81, 95% CI 0.76, 0.86), institutional delivery (aOR = 0.87, 95% CI 0.80, 0.94) and Post-natal Care (aOR = 0.76, 95% CI 0.62, 0.95) services. A decreasing linear trend was observed for four or more ANC visits (LRT P = 0.96) and institutional delivery (LRT P = 0.80) with increasing levels of IPV justification. Women justifying IPV were less likely to have at least one ANC visit in urban (aOR 0.67, 95% CI 0.60, 0.75) compared to rural areas (aOR 0.83, 95% CI 0.73, 0.94). CONCLUSIONS: Women's justification of IPV was associated with decreased odds of utilizing a wide range of maternal health care services at the regional level. Although further research that may help establish a causal link is
Published: 2022

5. Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-Adjusted life-years for 29 cancer groups, 1990 to 2017: A systematic analysis for the global burden of disease study

Author: Fitzmaurice, C, Abate, D, Abbasi, N, Abbastabar, H, Abd-Allah, F, Abdel-Rahman, O, Abdelalim, A, Abdoli, A, Abdollahpour, I, Abdulle, A, Abebe, N, Abraha, H, Abu-Raddad, L, Abualhasan, A, Adedeji, I, Advani, S, Afarideh, M, Afshari, M, Aghaali, M, Agius, D, Agrawal, S, Ahmadi, A, Ahmadian, E, Ahmadpour, E, Ahmed, M, Akbari, M, Akinyemiju, T, Al-Aly, Z, Alabdulkader, A, Alahdab, F, Alam, T, Alamene, G, Alemnew, B, Alene, K, Alinia, C, Alipour, V, Aljunid, S, Bakeshei, F, Almadi, M, Almasi-Hashiani, A, Alsharif, U, Alsowaidi, S, Alvis-Guzman, N, Amini, E, Amini, S, Amoako, Y, Anbari, Z, Anber, N, Andrei, C, Anjomshoa, M, Ansari, F, Ansariadi, A, Appiah, S, Arab-Zozani, M, Arabloo, J, Arefi, Z, Aremu, O, Areri, H, Artaman, A, Asayesh, H, Asfaw, E, Ashagre, A, Assadi, R, Ataeinia, B, Atalay, H, Ataro, Z, Atique, S, Ausloos, M, Avila-Burgos, L, Avokpaho, E, Awasthi, A, Awoke, N, Ayala Quintanilla, B, Ayanore, M, Ayele, H, Babaee, E, Bacha, U, Badawi, A, Bagherzadeh, M, Bagli, E, Balakrishnan, S, Balouchi, A, Barnighausen, T, Battista, R, Behzadifar, M, Bekele, B, Belay, Y, Belayneh, Y, Berfield, K, Berhane, A, Bernabe, E, Beuran, M, Bhakta, N, Bhattacharyya, K, Biadgo, B, Bijani, A, Bin Sayeed, M, Birungi, C, Bisignano, C, Bitew, H, Bjorge, T, Bleyer, A, Bogale, K, Bojia, H, Borzi, A, Bosetti, C, Bou-Orm, I, Brenner, H, Brewer, J, Briko, A, Briko, N, Bustamante-Teixeira, M, Butt, Z, Carreras, G, Carrero, J, Carvalho, F, Castro, C, Castro, F, Catala-Lopez, F, Cerin, E, Chaiah, Y, Chanie, W, Chattu, V, Chaturvedi, P, Chauhan, N, Chehrazi, M, Chiang, P, Chichiabellu, T, Chido-Amajuoyi, O, Chimed-Ochir, O, Choi, J, Christopher, D, Chu, D, Constantin, M, Costa, V, Crocetti, E, Crowe, C, Curado, M, Dahlawi, S, Damiani, G, Darwish, A, Daryani, A, Das Neves, J, Demeke, F, Demis, A, Demissie, B, Demoz, G, Denova-Gutierrez, E, Derakhshani, A, Deribe, K, Desai, R, Desalegn, B, Desta, M, Dey, S, Dharmaratne, S, Dhimal, M, Diaz, D, Dinberu, M, Djalalinia, S, Doku, D, Drake, T, Dubey, M, Dubljanin, E, Duken, E, Ebrahimi, H, Effiong, A, Eftekhari, A, El Sayed, I, Zaki, M, El-Jaafary, S, El-Khatib, Z, Elemineh, D, Elkout, H, Ellenbogen, R, Elsharkawy, A, Emamian, M, Endalew, D, Endries, A, Eshrati, B, Fadhil, I, Fallah, V, Faramarzi, M, Farhangi, M, Farioli, A, Farzadfar, F, Fentahun, N, Fernandes, E, Feyissa, G, Filip, I, Fischer, F, Fisher, J, Force, L, Foroutan, M, Freitas, M, Fukumoto, T, Futran, N, Gallus, S, Gankpe, F, Gayesa, R, Gebrehiwot, T, Gebremeskel, G, Gedefaw, G, Gelaw, B, Geta, B, Getachew, S, Gezae, K, Ghafourifard, M, Ghajar, A, Ghashghaee, A, Gholamian, A, Gill, P, Ginindza, T, Girmay, A, Gizaw, M, Gomez, R, Gopalani, S, Gorini, G, Goulart, B, Grada, A, Ribeiro Guerra, M, Guimaraes, A, Gupta, P, Gupta, R, Hadkhale, K, Haj-Mirzaian, A, Hamadeh, R, Hamidi, S, Hanfore, L, Haro, J, Hasankhani, M, Hasanzadeh, A, Hassen, H, Hay, R, Hay, S, Henok, A, Henry, N, Herteliu, C, Hidru, H, Hoang, C, Hole, M, Hoogar, P, Horita, N, Hosgood, H, Hosseini, M, Hosseinzadeh, M, Hostiuc, M, Hostiuc, S, Househ, M, Hussen, M, Ileanu, B, Ilic, M, Innos, K, Irvani, S, Iseh, K, Islam, S, Islami, F, Jafari Balalami, N, Jafarinia, M, Jahangiry, L, Jahani, M, Jahanmehr, N, Jakovljevic, M, James, S, Javanbakht, M, Jayaraman, S, Jee, S, Jenabi, E, Jha, R, Jonas, J, Jonnagaddala, J, Joo, T, Jungari, S, Jurisson, M, Kabir, A, Kamangar, F, Karch, A, Karimi, N, Karimian, A, Kasaeian, A, Kasahun, G, Kassa, B, Kassa, T, Kassaw, M, Kaul, A, Keiyoro, P, Kelbore, A, Kerbo, A, Khader, Y, Khalilarjmandi, M, Khan, E, Khan, G, Khang, Y, Khatab, K, Khater, A, Khayamzadeh, M, Khazaee-Pool, M, Khazaei, S, Khoja, A, Khosravi, M, Khubchandani, J, Kianipour, N, Kim, D, Kim, Y, Kisa, A, Kisa, S, Kissimova-Skarbek, K, Komaki, H, Koyanagi, A, Krohn, K, Bicer, B, Kugbey, N, Kumar, V, Kuupiel, D, La Vecchia, C, Lad, D, Lake, E, Lakew, A, Lal, D, Lami, F, Lan, Q, Lasrado, S, Lauriola, P, Lazarus, J, Leigh, J, Leshargie, C, Liao, Y, Limenih, M, Listl, S, Lopez, A, Lopukhov, P, Lunevicius, R, Madadin, M, Magdeldin, S, El Razek, H, Majeed, A, Maleki, A, Malekzadeh, R, Manafi, A, Manafi, N, Manamo, W, Mansourian, M, Mansournia, M, Mantovani, L, Maroufizadeh, S, Martini, S, Mashamba-Thompson, T, Massenburg, B, Maswabi, M, Mathur, M, Mcalinden, C, Mckee, M, Meheretu, H, Mehrotra, R, Mehta, V, Meier, T, Melaku, Y, Meles, G, Meles, H, Melese, A, Melku, M, Memiah, P, Mendoza, W, Menezes, R, Merat, S, Meretoja, T, Mestrovic, T, Miazgowski, B, Miazgowski, T, Mihretie, K, Miller, T, Mills, E, Mir, S, Mirzaei, H, Mishra, R, Moazen, B, Mohammad, D, Mohammad, K, Mohammad, Y, Darwesh, A, Mohammadbeigi, A, Mohammadi, H, Mohammadi, M, Mohammadian, M, Mohammadian-Hafshejani, A, Mohammadoo-Khorasani, M, Mohammadpourhodki, R, Mohammed, A, Mohammed, J, Mohammed, S, Mohebi, F, Mokdad, A, Monasta, L, Moodley, Y, Moosazadeh, M, Moossavi, M, Moradi, G, Moradi-Joo, M, Moradi-Lakeh, M, Moradpour, F, Morawska, L, Morgado-Da-costa, J, Morisaki, N, Morrison, S, Mosapour, A, Mousavi, S, Muche, A, Muhammed, O, Musa, J, Nabhan, A, Naderi, M, Nagarajan, A, Nagel, G, Nahvijou, A, Naik, G, Najafi, F, Naldi, L, Nam, H, Nasiri, N, Nazari, J, Negoi, I, Neupane, S, Newcomb, P, Nggada, H, Ngunjiri, J, Nguyen, C, Nikniaz, L, Ningrum, D, Nirayo, Y, Nixon, M, Nnaji, C, Nojomi, M, Nosratnejad, S, Shiadeh, M, Obsa, M, Ofori-Asenso, R, Ogbo, F, Oh, I, Olagunju, A, Olagunju, T, Oluwasanu, M, Omonisi, A, Onwujekwe, O, Oommen, A, Oren, E, Ortega-Altamirano, D, Ota, E, Otstavnov, S, Owolabi, M, P A, M, Padubidri, J, Pakhale, S, Pakpour, A, Pana, A, Park, E, Parsian, H, Pashaei, T, Patel, S, Patil, S, Pennini, A, Pereira, D, Piccinelli, C, Pillay, J, Pirestani, M, Pishgar, F, Postma, M, Pourjafar, H, Pourmalek, F, Pourshams, A, Prakash, S, Prasad, N, Qorbani, M, Rabiee, M, Rabiee, N, Radfar, A, Rafiei, A, Rahim, F, Rahimi, M, Rahman, M, Rajati, F, Rana, S, Raoofi, S, Rath, G, Rawaf, D, Rawaf, S, Reiner, R, Renzaho, A, Rezaei, N, Rezapour, A, Ribeiro, A, Ribeiro, D, Ronfani, L, Roro, E, Roshandel, G, Rostami, A, Saad, R, Sabbagh, P, Sabour, S, Saddik, B, Safiri, S, Sahebkar, A, Salahshoor, M, Salehi, F, Salem, H, Salem, M, Salimzadeh, H, Salomon, J, Samy, A, Sanabria, J, Santric Milicevic, M, Sartorius, B, Sarveazad, A, Sathian, B, Satpathy, M, Savic, M, Sawhney, M, Sayyah, M, Schneider, I, Schottker, B, Sekerija, M, Sepanlou, S, Sepehrimanesh, M, Seyedmousavi, S, Shaahmadi, F, Shabaninejad, H, Shahbaz, M, Shaikh, M, Shamshirian, A, Shamsizadeh, M, Sharafi, H, Sharafi, Z, Sharif, M, Sharifi, A, Sharifi, H, Sharma, R, Sheikh, A, Shirkoohi, R, Shukla, S, Si, S, Siabani, S, Silva, D, Silveira, D, Singh, A, Singh, J, Sisay, S, Sitas, F, Sobngwi, E, Soofi, M, Soriano, J, Stathopoulou, V, Sufiyan, M, Tabares-Seisdedos, R, Tabuchi, T, Takahashi, K, Tamtaji, O, Tarawneh, M, Tassew, S, Taymoori, P, Tehrani-Banihashemi, A, Temsah, M, Temsah, O, Tesfay, B, Tesfay, F, Teshale, M, Tessema, G, Thapa, S, Tlaye, K, Topor-Madry, R, Tovani-Palone, M, Traini, E, Tran, B, Tran, K, Tsadik, A, Ullah, I, Uthman, O, Vacante, M, Vaezi, M, Varona Perez, P, Veisani, Y, Vidale, S, Violante, F, Vlassov, V, Vollset, S, Vos, T, Vosoughi, K, Vu, G, Vujcic, I, Wabinga, H, Wachamo, T, Wagnew, F, Waheed, Y, Weldegebreal, F, Weldesamuel, G, Wijeratne, T, Wondafrash, D, Wonde, T, Wondmieneh, A, Workie, H, Yadav, R, Yadegar, A, Yadollahpour, A, Yaseri, M, Yazdi-Feyzabadi, V, Yeshaneh, A, Yimam, M, Yimer, E, Yisma, E, Yonemoto, N, Younis, M, Yousefi, B, Yousefifard, M, Yu, C, Zabeh, E, Zadnik, V, Moghadam, T, Zaidi, Z, Zamani, M, Zandian, H, Zangeneh, A, Zaki, L, Zendehdel, K, Zenebe, Z, Zewale, T, Ziapour, A, Zodpey, S, Murray, C, Fitzmaurice C., Abate D., Abbasi N., Abbastabar H., Abd-Allah F., Abdel-Rahman O., Abdelalim A., Abdoli A., Abdollahpour I., Abdulle A. S. M., Abebe N. D., Abraha H. N., Abu-Raddad L. J., Abualhasan A., Adedeji I. A., Advani S. M., Afarideh M., Afshari M., Aghaali M., Agius D., Agrawal S., Ahmadi A., Ahmadian E., Ahmadpour E., Ahmed M. B., Akbari M. E., Akinyemiju T., Al-Aly Z., Alabdulkader A. M., Alahdab F., Alam T., Alamene G. M., Alemnew B. T. T., Alene K. A., Alinia C., Alipour V., Aljunid S. M., Bakeshei F. A., Almadi M. A. H., Almasi-Hashiani A., Alsharif U., Alsowaidi S., Alvis-Guzman N., Amini E., Amini S., Amoako Y. A., Anbari Z., Anber N. H., Andrei C. L., Anjomshoa M., Ansari F., Ansariadi A., Appiah S. C. Y., Arab-Zozani M., Arabloo J., Arefi Z., Aremu O., Areri H. A., Artaman A., Asayesh H., Asfaw E. T., Ashagre A. F., Assadi R., Ataeinia B., Atalay H. T., Ataro Z., Atique S., Ausloos M., Avila-Burgos L., Avokpaho E. F. G. A., Awasthi A., Awoke N., Ayala Quintanilla B. P., Ayanore M. A., Ayele H. T., Babaee E., Bacha U., Badawi A., Bagherzadeh M., Bagli E., Balakrishnan S., Balouchi A., Barnighausen T. W., Battista R. J., Behzadifar M., Bekele B. B., Belay Y. B., Belayneh Y. M., Berfield K. K. S., Berhane A., Bernabe E., Beuran M., Bhakta N., Bhattacharyya K., Biadgo B., Bijani A., Bin Sayeed M. S., Birungi C., Bisignano C., Bitew H., Bjorge T., Bleyer A., Bogale K. A., Bojia H. A., Borzi A. M., Bosetti C., Bou-Orm I. R., Brenner H., Brewer J. D., Briko A. N., Briko N. I., Bustamante-Teixeira M. T., Butt Z. A., Carreras G., Carrero J. J., Carvalho F., Castro C., Castro F., Catala-Lopez F., Cerin E., Chaiah Y., Chanie W. F., Chattu V. K., Chaturvedi P., Chauhan N. S., Chehrazi M., Chiang P. P. -C., Chichiabellu T. Y., Chido-Amajuoyi O. G., Chimed-Ochir O., Choi J. -Y. J., Christopher D. J., Chu D. -T., Constantin M. -M., Costa V. M., Crocetti E., Crowe C. S., Curado M. P., Dahlawi S. M. A., Damiani G., Darwish A. H., Daryani A., Das Neves J., Demeke F. M., Demis A. B., Demissie B. W., Demoz G. T., Denova-Gutierrez E., Derakhshani A., Deribe K. S., Desai R., Desalegn B. B., Desta M., Dey S., Dharmaratne S. D., Dhimal M., Diaz D., Dinberu M. T. T., Djalalinia S., Doku D. T., Drake T. M., Dubey M., Dubljanin E., Duken E. E., Ebrahimi H., Effiong A., Eftekhari A., El Sayed I., Zaki M. E. S., El-Jaafary S. I., El-Khatib Z., Elemineh D. A., Elkout H., Ellenbogen R. G., Elsharkawy A., Emamian M. H., Endalew D. A., Endries A. Y., Eshrati B., Fadhil I., Fallah V., Faramarzi M., Farhangi M. A., Farioli A., Farzadfar F., Fentahun N., Fernandes E., Feyissa G. T., Filip I., Fischer F., Fisher J. L., Force L. M., Foroutan M., Freitas M., Fukumoto T., Futran N. D., Gallus S., Gankpe F. G., Gayesa R. T., Gebrehiwot T. T., Gebremeskel G. G., Gedefaw G. A., Gelaw B. K., Geta B., Getachew S., Gezae K. E., Ghafourifard M., Ghajar A., Ghashghaee A., Gholamian A., Gill P. S., Ginindza T. T. G., Girmay A., Gizaw M., Gomez R. S., Gopalani S. V., Gorini G., Goulart B. N. G., Grada A., Ribeiro Guerra M., Guimaraes A. L. S., Gupta P. C., Gupta R., Hadkhale K., Haj-Mirzaian A., Hamadeh R. R., Hamidi S., Hanfore L. K., Haro J. M., Hasankhani M., Hasanzadeh A., Hassen H. Y., Hay R. J., Hay S. I., Henok A., Henry N. J., Herteliu C., Hidru H. D., Hoang C. L., Hole M. K., Hoogar P., Horita N., Hosgood H. D., Hosseini M., Hosseinzadeh M., Hostiuc M., Hostiuc S., Househ M., Hussen M. M., Ileanu B., Ilic M. D., Innos K., Irvani S. S. N., Iseh K. R., Islam S. M. S., Islami F., Jafari Balalami N., Jafarinia M., Jahangiry L., Jahani M. A., Jahanmehr N., Jakovljevic M., James S. L., Javanbakht M., Jayaraman S., Jee S. H., Jenabi E., Jha R. P., Jonas J. B., Jonnagaddala J., Joo T., Jungari S. B., Jurisson M., Kabir A., Kamangar F., Karch A., Karimi N., Karimian A., Kasaeian A., Kasahun G. G., Kassa B., Kassa T. D., Kassaw M. W., Kaul A., Keiyoro P. N., Kelbore A. G., Kerbo A. A., Khader Y. S., Khalilarjmandi M., Khan E. A., Khan G., Khang Y. -H., Khatab K., Khater A., Khayamzadeh M., Khazaee-Pool M., Khazaei S., Khoja A. T., Khosravi M. H., Khubchandani J., Kianipour N., Kim D., Kim Y. J., Kisa A., Kisa S., Kissimova-Skarbek K., Komaki H., Koyanagi A., Krohn K. J., Bicer B. K., Kugbey N., Kumar V., Kuupiel D., La Vecchia C., Lad D. P., Lake E. A., Lakew A. M., Lal D. K., Lami F. H., Lan Q., Lasrado S., Lauriola P., Lazarus J. V., Leigh J., Leshargie C. T., Liao Y., Limenih M. A., Listl S., Lopez A. D., Lopukhov P. D., Lunevicius R., Madadin M., Magdeldin S., El Razek H. M. A., Majeed A., Maleki A., Malekzadeh R., Manafi A., Manafi N., Manamo W. A., Mansourian M., Mansournia M. A., Mantovani L. G., Maroufizadeh S., Martini S. M. S., Mashamba-Thompson T. P., Massenburg B. B., Maswabi M. T., Mathur M. R., McAlinden C., McKee M., Meheretu H. A. A., Mehrotra R., Mehta V., Meier T., Melaku Y. A., Meles G. G., Meles H. G., Melese A., Melku M., Memiah P. T. N., Mendoza W., Menezes R. G., Merat S., Meretoja T. J., Mestrovic T., Miazgowski B., Miazgowski T., Mihretie K. M. M., Miller T. R., Mills E. J., Mir S. M., Mirzaei H., Mirzaei H. R., Mishra R., Moazen B., Mohammad D. K., Mohammad K. A., Mohammad Y., Darwesh A. M., Mohammadbeigi A., Mohammadi H., Mohammadi M., Mohammadian M., Mohammadian-Hafshejani A., Mohammadoo-Khorasani M., Mohammadpourhodki R., Mohammed A. S., Mohammed J. A., Mohammed S., Mohebi F., Mokdad A. H., Monasta L., Moodley Y., Moosazadeh M., Moossavi M., Moradi G., Moradi-Joo M., Moradi-Lakeh M., Moradpour F., Morawska L., Morgado-Da-costa J., Morisaki N., Morrison S. D., Mosapour A., Mousavi S. M., Muche A. A., Muhammed O. S. S., Musa J., Nabhan A. R., Naderi M., Nagarajan A. J., Nagel G., Nahvijou A., Naik G., Najafi F., Naldi L., Nam H. S., Nasiri N., Nazari J., Negoi I., Neupane S., Newcomb P. A., Nggada H. A., Ngunjiri J. W., Nguyen C. T., Nikniaz L., Ningrum D. N. A., Nirayo Y. L., Nixon M. R., Nnaji C. A., Nojomi M., Nosratnejad S., Shiadeh M. N., Obsa M. S., Ofori-Asenso R., Ogbo F. A., Oh I. -H., Olagunju A. T., Olagunju T. O., Oluwasanu M. M., Omonisi A. E., Onwujekwe O. E., Oommen A. M., Oren E., Ortega-Altamirano D. D. V., Ota E., Otstavnov S. S., Owolabi M. O., P A M., Padubidri J. R., Pakhale S., Pakpour A. H., Pana A., Park E. -K., Parsian H., Pashaei T., Patel S., Patil S. T., Pennini A., Pereira D. M., Piccinelli C., Pillay J. D., Pirestani M., Pishgar F., Postma M. J., Pourjafar H., Pourmalek F., Pourshams A., Prakash S., Prasad N., Qorbani M., Rabiee M., Rabiee N., Radfar A., Rafiei A., Rahim F., Rahimi M., Rahman M. A., Rajati F., Rana S. M., Raoofi S., Rath G. K., Rawaf D. L., Rawaf S., Reiner R. C., Renzaho A. M. N., Rezaei N., Rezapour A., Ribeiro A. I., Ribeiro D., Ronfani L., Roro E. M., Roshandel G., Rostami A., Saad R. S., Sabbagh P., Sabour S., Saddik B., Safiri S., Sahebkar A., Salahshoor M. R., Salehi F., Salem H., Salem M. R., Salimzadeh H., Salomon J. A., Samy A. M., Sanabria J., Santric Milicevic M. M., Sartorius B., Sarveazad A., Sathian B., Satpathy M., Savic M., Sawhney M., Sayyah M., Schneider I. J. C., Schottker B., Sekerija M., Sepanlou S. G., Sepehrimanesh M., Seyedmousavi S., Shaahmadi F., Shabaninejad H., Shahbaz M., Shaikh M. A., Shamshirian A., Shamsizadeh M., Sharafi H., Sharafi Z., Sharif M., Sharifi A., Sharifi H., Sharma R., Sheikh A., Shirkoohi R., Shukla S. R., Si S., Siabani S., Silva D. A. S., Silveira D. G. A., Singh A., Singh J. A., Sisay S., Sitas F., Sobngwi E., Soofi M., Soriano J. B., Stathopoulou V., Sufiyan M. B., Tabares-Seisdedos R., Tabuchi T., Takahashi K., Tamtaji O. R., Tarawneh M. R., Tassew S. G., Taymoori P., Tehrani-Banihashemi A., Temsah M. -H., Temsah O., Tesfay B. E., Tesfay F. H., Teshale M. Y., Tessema G. A., Thapa S., Tlaye K. G., Topor-Madry R., Tovani-Palone M. R., Traini E., Tran B. X., Tran K. B., Tsadik A. G., Ullah I., Uthman O. A., Vacante M., Vaezi M., Varona Perez P., Veisani Y., Vidale S., Violante F. S., Vlassov V., Vollset S. E., Vos T., Vosoughi K., Vu G. T., Vujcic I. S., Wabinga H., Wachamo T. M., Wagnew F. S., Waheed Y., Weldegebreal F., Weldesamuel G. T., Wijeratne T., Wondafrash D. Z., Wonde T. E., Wondmieneh A. B., Workie H. M., Yadav R., Yadegar A., Yadollahpour A., Yaseri M., Yazdi-Feyzabadi V., Yeshaneh A., Yimam M. A., Yimer E. M., Yisma E., Yonemoto N., Younis M. Z., Yousefi B., Yousefifard M., Yu C., Zabeh E., Zadnik V., Moghadam T. Z., Zaidi Z., Zamani M., Zandian H., Zangeneh A., Zaki L., Zendehdel K., Zenebe Z. M., Zewale T. A., Ziapour A., Zodpey S., Murray C. J. L., Fitzmaurice, C, Abate, D, Abbasi, N, Abbastabar, H, Abd-Allah, F, Abdel-Rahman, O, Abdelalim, A, Abdoli, A, Abdollahpour, I, Abdulle, A, Abebe, N, Abraha, H, Abu-Raddad, L, Abualhasan, A, Adedeji, I, Advani, S, Afarideh, M, Afshari, M, Aghaali, M, Agius, D, Agrawal, S, Ahmadi, A, Ahmadian, E, Ahmadpour, E, Ahmed, M, Akbari, M, Akinyemiju, T, Al-Aly, Z, Alabdulkader, A, Alahdab, F, Alam, T, Alamene, G, Alemnew, B, Alene, K, Alinia, C, Alipour, V, Aljunid, S, Bakeshei, F, Almadi, M, Almasi-Hashiani, A, Alsharif, U, Alsowaidi, S, Alvis-Guzman, N, Amini, E, Amini, S, Amoako, Y, Anbari, Z, Anber, N, Andrei, C, Anjomshoa, M, Ansari, F, Ansariadi, A, Appiah, S, Arab-Zozani, M, Arabloo, J, Arefi, Z, Aremu, O, Areri, H, Artaman, A, Asayesh, H, Asfaw, E, Ashagre, A, Assadi, R, Ataeinia, B, Atalay, H, Ataro, Z, Atique, S, Ausloos, M, Avila-Burgos, L, Avokpaho, E, Awasthi, A, Awoke, N, Ayala Quintanilla, B, Ayanore, M, Ayele, H, Babaee, E, Bacha, U, Badawi, A, Bagherzadeh, M, Bagli, E, 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Abstract: Importance: Cancer and other noncommunicable diseases (NCDs) are now widely recognized as a threat to global development. The latest United Nations high-level meeting on NCDs reaffirmed this observation and also highlighted the slow progress in meeting the 2011 Political Declaration on the Prevention and Control of Noncommunicable Diseases and the third Sustainable Development Goal. Lack of situational analyses, priority setting, and budgeting have been identified as major obstacles in achieving these goals. All of these have in common that they require information on the local cancer epidemiology. The Global Burden of Disease (GBD) study is uniquely poised to provide these crucial data. Objective: To describe cancer burden for 29 cancer groups in 195 countries from 1990 through 2017 to provide data needed for cancer control planning. Evidence Review: We used the GBD study estimation methods to describe cancer incidence, mortality, years lived with disability, years of life lost, and disability-Adjusted life-years (DALYs). Results are presented at the national level as well as by Socio-demographic Index (SDI), a composite indicator of income, educational attainment, and total fertility rate. We also analyzed the influence of the epidemiological vs the demographic transition on cancer incidence. Findings: In 2017, there were 24.5 million incident cancer cases worldwide (16.8 million without nonmelanoma skin cancer [NMSC]) and 9.6 million cancer deaths. The majority of cancer DALYs came from years of life lost (97%), and only 3% came from years lived with disability. The odds of developing cancer were the lowest in the low SDI quintile (1 in 7) and the highest in the high SDI quintile (1 in 2) for both sexes. In 2017, the most common incident cancers in men were NMSC (4.3 million incident cases); tracheal, bronchus, and lung (TBL) cancer (1.5 million incident cases); and prostate cancer (1.3 million incident cases). The most common causes of cancer deaths and DALYs fo
Published: 2019

6. Hospital Resilience After the 2015 Earthquake in Nepal: Results From Semi-structured Interviews With Hospital Staff

Author: Almeida, M. Moitinho de, Loenhout, J.A.F. van, Thapa, S. Singh, Kumar, K.C., Mahara, D. Prakash, Guha-Sapir, D., Aujoulat, I., Almeida, M. Moitinho de, Loenhout, J.A.F. van, Thapa, S. Singh, Kumar, K.C., Mahara, D. Prakash, Guha-Sapir, D., and Aujoulat, I.
Abstract: Contains fulltext : 232445.pdf (Publisher’s version ) (Open Access), Background: Resilient hospitals are increasingly recognized as a cornerstone of disaster reduction in global policies such as the Sendai Framework for Action. However, current hospital resilience frameworks emerged from pre-disaster conceptualizations, and have not been verified in real-life disaster contexts nor in the frontlines. Our aim was to study a tertiary hospital's resilience after the 2015 earthquake in Nepal, as experienced by its staff. Methods: We undertook a qualitative study in the Tribhuvan University Teaching Hospital (TUTH), where we conducted 18 semi-structured interviews with hospital staff. We inductively created themes to describe the earthquake burden to the hospital, and to analyze individual resilience of hospital staff. In addition, we deductively documented the resilience of the hospital as a system, according to the system resilience dimensions: means of resilience (redundancy and resourcefulness), and ends of resilience (robustness and rapidity). Results: In terms of robustness, TUTH increased its capacity for earthquake victims as elective activities were temporarily interrupted and quality of care was not a priority. Three stages of rapidity were identified: critical rapidity to address immediate needs, stabilizing rapidity until the hospital re-started routine activities, and recovery rapidity. In addition to the disaster plan, emerging adaptations played a major role in redundancy and resourcefulness. We found that individual resilience depended on three determinants: safety, meaningfulness, and sense of belonging. Conclusions: Hospital resilience results from a complexity of emerging and planned adaptations, as well as from interdependencies with individual resilience. Frameworks and plans to improve hospital resilience must reflect flexibility of response, and a concern for well-being of hospital staff is central for sustainable disaster response and improved resilience.
Published: 2021

7. Hospital Resilience After the 2015 Earthquake in Nepal: Results From Semi-structured Interviews With Hospital Staff

Author: Almeida, M. Moitinho de, Loenhout, J.A.F. van, Thapa, S. Singh, Kumar, K.C., Mahara, D. Prakash, Guha-Sapir, D., Aujoulat, I., Almeida, M. Moitinho de, Loenhout, J.A.F. van, Thapa, S. Singh, Kumar, K.C., Mahara, D. Prakash, Guha-Sapir, D., and Aujoulat, I.
Abstract: Contains fulltext : 232445.pdf (Publisher’s version ) (Open Access), Background: Resilient hospitals are increasingly recognized as a cornerstone of disaster reduction in global policies such as the Sendai Framework for Action. However, current hospital resilience frameworks emerged from pre-disaster conceptualizations, and have not been verified in real-life disaster contexts nor in the frontlines. Our aim was to study a tertiary hospital's resilience after the 2015 earthquake in Nepal, as experienced by its staff. Methods: We undertook a qualitative study in the Tribhuvan University Teaching Hospital (TUTH), where we conducted 18 semi-structured interviews with hospital staff. We inductively created themes to describe the earthquake burden to the hospital, and to analyze individual resilience of hospital staff. In addition, we deductively documented the resilience of the hospital as a system, according to the system resilience dimensions: means of resilience (redundancy and resourcefulness), and ends of resilience (robustness and rapidity). Results: In terms of robustness, TUTH increased its capacity for earthquake victims as elective activities were temporarily interrupted and quality of care was not a priority. Three stages of rapidity were identified: critical rapidity to address immediate needs, stabilizing rapidity until the hospital re-started routine activities, and recovery rapidity. In addition to the disaster plan, emerging adaptations played a major role in redundancy and resourcefulness. We found that individual resilience depended on three determinants: safety, meaningfulness, and sense of belonging. Conclusions: Hospital resilience results from a complexity of emerging and planned adaptations, as well as from interdependencies with individual resilience. Frameworks and plans to improve hospital resilience must reflect flexibility of response, and a concern for well-being of hospital staff is central for sustainable disaster response and improved resilience.
Published: 2021

8. Exploiting Linguistic Information from Nepali Transcripts for Early Detection of Alzheimer's Disease using Natural Language Processing and Machine Learning Techniques

Author: Adhikari, S, Thapa, S, Naseem, U, Singh, P, Huo, H, Bharathy, G, Prasad, M, Adhikari, S, Thapa, S, Naseem, U, Singh, P, Huo, H, Bharathy, G, and Prasad, M
Published: 2021

9. Hospital Resilience After the 2015 Earthquake in Nepal: Results From Semi-structured Interviews With Hospital Staff

Author: Almeida, M. Moitinho de, Loenhout, J.A.F. van, Thapa, S. Singh, Kumar, K.C., Mahara, D. Prakash, Guha-Sapir, D., Aujoulat, I., Almeida, M. Moitinho de, Loenhout, J.A.F. van, Thapa, S. Singh, Kumar, K.C., Mahara, D. Prakash, Guha-Sapir, D., and Aujoulat, I.
Abstract: Contains fulltext : 232445.pdf (Publisher’s version ) (Open Access), Background: Resilient hospitals are increasingly recognized as a cornerstone of disaster reduction in global policies such as the Sendai Framework for Action. However, current hospital resilience frameworks emerged from pre-disaster conceptualizations, and have not been verified in real-life disaster contexts nor in the frontlines. Our aim was to study a tertiary hospital's resilience after the 2015 earthquake in Nepal, as experienced by its staff. Methods: We undertook a qualitative study in the Tribhuvan University Teaching Hospital (TUTH), where we conducted 18 semi-structured interviews with hospital staff. We inductively created themes to describe the earthquake burden to the hospital, and to analyze individual resilience of hospital staff. In addition, we deductively documented the resilience of the hospital as a system, according to the system resilience dimensions: means of resilience (redundancy and resourcefulness), and ends of resilience (robustness and rapidity). Results: In terms of robustness, TUTH increased its capacity for earthquake victims as elective activities were temporarily interrupted and quality of care was not a priority. Three stages of rapidity were identified: critical rapidity to address immediate needs, stabilizing rapidity until the hospital re-started routine activities, and recovery rapidity. In addition to the disaster plan, emerging adaptations played a major role in redundancy and resourcefulness. We found that individual resilience depended on three determinants: safety, meaningfulness, and sense of belonging. Conclusions: Hospital resilience results from a complexity of emerging and planned adaptations, as well as from interdependencies with individual resilience. Frameworks and plans to improve hospital resilience must reflect flexibility of response, and a concern for well-being of hospital staff is central for sustainable disaster response and improved resilience.
Published: 2021

10. Exploiting Linguistic Information from Nepali Transcripts for Early Detection of Alzheimer's Disease using Natural Language Processing and Machine Learning Techniques

Author: Adhikari, S, Thapa, S, Naseem, U, Singh, P, Huo, H, Bharathy, G, Prasad, M, Adhikari, S, Thapa, S, Naseem, U, Singh, P, Huo, H, Bharathy, G, and Prasad, M
Published: 2021

11. A Comparative Study of Machine Learning and NLP Techniques for Uses of Stop Words by Patients in Diagnosis of Alzheimer's Disease

Author: Adhikari, S, Thapa, S, Singh, P, Huo, H, Bharathy, G, Prasad, M, Adhikari, S, Thapa, S, Singh, P, Huo, H, Bharathy, G, and Prasad, M
Abstract: Alzheimer's Disease (AD) is one of the most common forms of neuropsychological disorder in elderly people. It is a slow progressive disease affecting the brain cells. This affects the cognitive abilities of people and their daily activities. During the course of the disease, memory gets brutally affected too. Working as well as long-term declarative memory deteriorates in AD patients. Due to this deterioration of the memory, AD patients tend to show a decline in their communicative skills as well. This decline is reflected in their speech. AD patients usually have poor grammar along with very low coherent ideas. Also, they tend to repeat the words very often and hence become unclear on the message they are trying to convey. As the disease progresses, the speech is completely impaired, and the patients are left to sing or utter words that are totally out of context. Stopwords are the words that are most commonly used in language and it is often hypothesized that AD patients use them much often as compared to Control Normal (CN) subjects. It is seen that due to the degeneration of brain cells in AD patients, they have a tendency to use a lot of stopwords to fill their perplexities in their statements. In this paper, the usefulness of the stopwords in capturing the linguistic information of the patients suffering from AD are discussed. Learning algorithms are evaluated by including stopwords and dropping stopwords at preprocessing to draw comparisons.
Published: 2021

12. Evaluating assumptions of scales for subjective assessment of thermal environments – Do laypersons perceive them the way, we researchers believe?

Author: Schweiker, M, Schweiker, M, André, M, Al-Atrash, F, Al-Khatri, H, Alprianti, RR, Alsaad, H, Amin, R, Ampatzi, E, Arsano, AY, Azar, E, Bannazadeh, B, Batagarawa, A, Becker, S, Buonocore, C, Cao, B, Choi, JH, Chun, C, Daanen, H, Damiati, SA, Daniel, L, De Vecchi, R, Dhaka, S, Domínguez-Amarillo, S, Dudkiewicz, E, Edappilly, LP, Fernández-Agüera, J, Folkerts, M, Frijns, A, Gaona, G, Garg, V, Gauthier, S, Jabbari, SG, Harimi, D, Hellwig, RT, Huebner, GM, Jin, Q, Jowkar, M, Kim, J, King, N, Kingma, B, Koerniawan, MD, Kolarik, J, Kumar, S, Kwok, A, Lamberts, R, Laska, M, Lee, MCJ, Lee, Y, Lindermayr, V, Mahaki, M, Marcel-Okafor, U, Marín-Restrepo, L, Marquardsen, A, Martellotta, F, Mathur, J, Mino-Rodriguez, I, Montazami, A, Mou, D, Moujalled, B, Nakajima, M, Ng, E, Okafor, M, Olweny, M, Ouyang, W, Papst de Abreu, AL, Pérez-Fargallo, A, Rajapaksha, I, Ramos, G, Rashid, S, Reinhart, CF, Rivera, MI, Salmanzadeh, M, Schakib-Ekbatan, K, Schiavon, S, Shooshtarian, S, Shukuya, M, Soebarto, V, Suhendri, S, Tahsildoost, M, Tartarini, F, Teli, D, Tewari, P, Thapa, S, Trebilcock, M, Trojan, J, Tukur, RB, Voelker, C, Yam, Y, Yang, L, Zapata-Lancaster, G, Zhai, Y, Zhu, Y, Zomorodian, ZS, Schweiker, M, Schweiker, M, André, M, Al-Atrash, F, Al-Khatri, H, Alprianti, RR, Alsaad, H, Amin, R, Ampatzi, E, Arsano, AY, Azar, E, Bannazadeh, B, Batagarawa, A, Becker, S, Buonocore, C, Cao, B, Choi, JH, Chun, C, Daanen, H, Damiati, SA, Daniel, L, De Vecchi, R, Dhaka, S, Domínguez-Amarillo, S, Dudkiewicz, E, Edappilly, LP, Fernández-Agüera, J, Folkerts, M, Frijns, A, Gaona, G, Garg, V, Gauthier, S, Jabbari, SG, Harimi, D, Hellwig, RT, Huebner, GM, Jin, Q, Jowkar, M, Kim, J, King, N, Kingma, B, Koerniawan, MD, Kolarik, J, Kumar, S, Kwok, A, Lamberts, R, Laska, M, Lee, MCJ, Lee, Y, Lindermayr, V, Mahaki, M, Marcel-Okafor, U, Marín-Restrepo, L, Marquardsen, A, Martellotta, F, Mathur, J, Mino-Rodriguez, I, Montazami, A, Mou, D, Moujalled, B, Nakajima, M, Ng, E, Okafor, M, Olweny, M, Ouyang, W, Papst de Abreu, AL, Pérez-Fargallo, A, Rajapaksha, I, Ramos, G, Rashid, S, Reinhart, CF, Rivera, MI, Salmanzadeh, M, Schakib-Ekbatan, K, Schiavon, S, Shooshtarian, S, Shukuya, M, Soebarto, V, Suhendri, S, Tahsildoost, M, Tartarini, F, Teli, D, Tewari, P, Thapa, S, Trebilcock, M, Trojan, J, Tukur, RB, Voelker, C, Yam, Y, Yang, L, Zapata-Lancaster, G, Zhai, Y, Zhu, Y, and Zomorodian, ZS
Abstract: People's subjective response to any thermal environment is commonly investigated by using rating scales describing the degree of thermal sensation, comfort, and acceptability. Subsequent analyses of results collected in this way rely on the assumption that specific distances between verbal anchors placed on the scale exist and that relationships between verbal anchors from different dimensions that are assessed (e.g. thermal sensation and comfort) do not change. Another inherent assumption is that such scales are independent of the context in which they are used (climate zone, season, etc.). Despite their use worldwide, there is indication that contextual differences influence the way the scales are perceived and therefore question the reliability of the scales’ interpretation. To address this issue, a large international collaborative questionnaire study was conducted in 26 countries, using 21 different languages, which led to a dataset of 8225 questionnaires. Results, analysed by means of robust statistical techniques, revealed that only a subset of the responses are in accordance with the mentioned assumptions. Significant differences appeared between groups of participants in their perception of the scales, both in relation to distances of the anchors and relationships between scales. It was also found that respondents’ interpretations of scales changed with contextual factors, such as climate, season, and language. These findings highlight the need to carefully consider context-dependent factors in interpreting and reporting results from thermal comfort studies or post-occupancy evaluations, as well as to revisit the use of rating scales and the analysis methods used in thermal comfort studies to improve their reliability.
Published: 2020

13. Evaluating assumptions of scales for subjective assessment of thermal environments – Do laypersons perceive them the way, we researchers believe?

Author: Schweiker, M, Schweiker, M, André, M, Al-Atrash, F, Al-Khatri, H, Alprianti, RR, Alsaad, H, Amin, R, Ampatzi, E, Arsano, AY, Azar, E, Bannazadeh, B, Batagarawa, A, Becker, S, Buonocore, C, Cao, B, Choi, JH, Chun, C, Daanen, H, Damiati, SA, Daniel, L, De Vecchi, R, Dhaka, S, Domínguez-Amarillo, S, Dudkiewicz, E, Edappilly, LP, Fernández-Agüera, J, Folkerts, M, Frijns, A, Gaona, G, Garg, V, Gauthier, S, Jabbari, SG, Harimi, D, Hellwig, RT, Huebner, GM, Jin, Q, Jowkar, M, Kim, J, King, N, Kingma, B, Koerniawan, MD, Kolarik, J, Kumar, S, Kwok, A, Lamberts, R, Laska, M, Lee, MCJ, Lee, Y, Lindermayr, V, Mahaki, M, Marcel-Okafor, U, Marín-Restrepo, L, Marquardsen, A, Martellotta, F, Mathur, J, Mino-Rodriguez, I, Montazami, A, Mou, D, Moujalled, B, Nakajima, M, Ng, E, Okafor, M, Olweny, M, Ouyang, W, Papst de Abreu, AL, Pérez-Fargallo, A, Rajapaksha, I, Ramos, G, Rashid, S, Reinhart, CF, Rivera, MI, Salmanzadeh, M, Schakib-Ekbatan, K, Schiavon, S, Shooshtarian, S, Shukuya, M, Soebarto, V, Suhendri, S, Tahsildoost, M, Tartarini, F, Teli, D, Tewari, P, Thapa, S, Trebilcock, M, Trojan, J, Tukur, RB, Voelker, C, Yam, Y, Yang, L, Zapata-Lancaster, G, Zhai, Y, Zhu, Y, Zomorodian, ZS, Schweiker, M, Schweiker, M, André, M, Al-Atrash, F, Al-Khatri, H, Alprianti, RR, Alsaad, H, Amin, R, Ampatzi, E, Arsano, AY, Azar, E, Bannazadeh, B, Batagarawa, A, Becker, S, Buonocore, C, Cao, B, Choi, JH, Chun, C, Daanen, H, Damiati, SA, Daniel, L, De Vecchi, R, Dhaka, S, Domínguez-Amarillo, S, Dudkiewicz, E, Edappilly, LP, Fernández-Agüera, J, Folkerts, M, Frijns, A, Gaona, G, Garg, V, Gauthier, S, Jabbari, SG, Harimi, D, Hellwig, RT, Huebner, GM, Jin, Q, Jowkar, M, Kim, J, King, N, Kingma, B, Koerniawan, MD, Kolarik, J, Kumar, S, Kwok, A, Lamberts, R, Laska, M, Lee, MCJ, Lee, Y, Lindermayr, V, Mahaki, M, Marcel-Okafor, U, Marín-Restrepo, L, Marquardsen, A, Martellotta, F, Mathur, J, Mino-Rodriguez, I, Montazami, A, Mou, D, Moujalled, B, Nakajima, M, Ng, E, Okafor, M, Olweny, M, Ouyang, W, Papst de Abreu, AL, Pérez-Fargallo, A, Rajapaksha, I, Ramos, G, Rashid, S, Reinhart, CF, Rivera, MI, Salmanzadeh, M, Schakib-Ekbatan, K, Schiavon, S, Shooshtarian, S, Shukuya, M, Soebarto, V, Suhendri, S, Tahsildoost, M, Tartarini, F, Teli, D, Tewari, P, Thapa, S, Trebilcock, M, Trojan, J, Tukur, RB, Voelker, C, Yam, Y, Yang, L, Zapata-Lancaster, G, Zhai, Y, Zhu, Y, and Zomorodian, ZS
Abstract: People's subjective response to any thermal environment is commonly investigated by using rating scales describing the degree of thermal sensation, comfort, and acceptability. Subsequent analyses of results collected in this way rely on the assumption that specific distances between verbal anchors placed on the scale exist and that relationships between verbal anchors from different dimensions that are assessed (e.g. thermal sensation and comfort) do not change. Another inherent assumption is that such scales are independent of the context in which they are used (climate zone, season, etc.). Despite their use worldwide, there is indication that contextual differences influence the way the scales are perceived and therefore question the reliability of the scales’ interpretation. To address this issue, a large international collaborative questionnaire study was conducted in 26 countries, using 21 different languages, which led to a dataset of 8225 questionnaires. Results, analysed by means of robust statistical techniques, revealed that only a subset of the responses are in accordance with the mentioned assumptions. Significant differences appeared between groups of participants in their perception of the scales, both in relation to distances of the anchors and relationships between scales. It was also found that respondents’ interpretations of scales changed with contextual factors, such as climate, season, and language. These findings highlight the need to carefully consider context-dependent factors in interpreting and reporting results from thermal comfort studies or post-occupancy evaluations, as well as to revisit the use of rating scales and the analysis methods used in thermal comfort studies to improve their reliability.
Published: 2020

14. Detecting Alzheimer’s Disease by Exploiting Linguistic Information from Nepali Transcript

Author: Thapa, S, Adhikari, S, Naseem, U, Singh, P, Bharathy, G, Prasad, M, Thapa, S, Adhikari, S, Naseem, U, Singh, P, Bharathy, G, and Prasad, M
Abstract: © 2020, Springer Nature Switzerland AG. Alzheimer’s disease (AD) is the most common form of neurodegenerating disorder accounting for 60–80% of all dementia cases. The lack of effective clinical treatment options to completely cure or even slow the progression of disease makes it even more serious. Treatment options are available to treat the milder stage of the disease to provide symptomatic short-term relief and improve quality of life. Early diagnosis is key in the treatment and management of AD as advanced stages of disease cause severe cognitive decline and permanent brain damage. This has prompted researchers to explore innovative ways to detect AD early on. Changes in speech are one of the main signs of AD patients. As the brain deteriorates the language processing ability of the patients deteriorates too. Previous research has been done in the English language using Natural Language Processing (NLP) techniques for early detection of AD. However, research using local languages and low resourced language like Nepali still lag behind. NLP is an important tool in Artificial Intelligence to decipher the human language and perform various tasks. In this paper, various classifiers have been discussed for the early detection of Alzheimer’s in the Nepali language. The proposed study makes a convincing conclusion that the difficulty in processing information in AD patients reflects in their speech while describing a picture. The study incorporates the speech decline of AD patients to classify them as control subjects or AD patients using various classifiers and NLP techniques. Furthermore, in this experiment a new dataset consisting of transcripts of AD patients and Control normal (CN) subjects in the Nepali language. In addition, this paper sets a baseline for the early detection of AD using NLP in the Nepali language.
Published: 2020

15. Data-Driven Approach based on Feature Selection Technique for Early Diagnosis of Alzheimer's Disease

Author: Thapa, S, Singh, P, Jain, DK, Bharill, N, Gupta, A, Prasad, M, Thapa, S, Singh, P, Jain, DK, Bharill, N, Gupta, A, and Prasad, M
Abstract: © 2020 IEEE. Alzheimer's disease (AD) is a neurodegenerative disorder resulting in memory loss and cognitive decline caused due to the death of brain cells. It is the most common form of dementia and accounts for 60-80% of all dementia cases. There is no single test for diagnosis of AD, the doctors rely on medical history, neuropsychological assessments, computed tomography (CT) or magnetic resonance imaging (MRI) scan of the brain, etc. to confirm a diagnosis. In terms of the treatment, currently, there is neither a cure nor any way to slow the progression of AD. However, for people with mild or moderate stages of this disease, there are some medications available to temporarily reduce symptoms and help to improve quality of life. Hence, early diagnosis of AD is extremely crucial for overall better management of the disease. The researches have shown some relation between neuropsychological scores and atrophies of the brain. This can be leveraged for the early diagnosis of AD. This paper makes use of feature selection techniques to extract the most important features in the diagnosis of AD. This paper demonstrates the need to combine neuropsychological scores like mini-mental state examination (MMSE) with MRI features to provide better decisional space for early diagnosis of AD. Through the experiments, including MMSE along with other features are found to improve the classification of AD, significantly.
Published: 2020

16. Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived with Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017 : A Systematic Analysis for the Global Burden of Disease Study

Author: Fitzmauric, C., Fitzmaurice, C., Abate, D., Abbasi, N., Abbastabar, H., Abd-Allah, F., Abdel-Rahman, O., Abdelalim, A., Abdoli, A., Abdollahpour, I., Abdulle, A. S. M., Abebe, N. D., Abraha, H. N., Abu-Raddad, L. J., Abualhasan, A., Adedeji, I. A., Advani, S. M., Afarideh, M., Afshari, M., Aghaali, M., Agius, D., Agrawal, S., Ahmadi, A., Ahmadian, E., Ahmadpour, E., Ahmed, M. B., Akbari, M. E., Akinyemiju, T., Al-Aly, Z., Alabdulkader, A. M., Alahdab, F., Alam, T., Alamene, G. M., Alemnew, B. T. T., Alene, K. A., Alinia, C., Alipour, V., Aljunid, S. M., Bakeshei, F. A., Almadi, M. A. H., Almasi-Hashiani, A., Alsharif, U., Alsowaidi, S., Alvis-Guzman, N., Amini, E., Amini, S., Amoako, Y. A., Anbari, Z., Anber, N. H., Andrei, C. L., Anjomshoa, M., Ansari, F., Ansariadi, A., Appiah, S. C. Y., Arab-Zozani, M., Arabloo, J., Arefi, Z., Aremu, O., Areri, H. A., Artaman, A., Asayesh, H., Asfaw, E. T., Ashagre, A. F., Assadi, R., Ataeinia, B., Atalay, H. T., Ataro, Z., Atique, S., Ausloos, M., Avila-Burgos, L., Avokpaho, E. F. G. A., Awasthi, A., Awoke, N., Ayala Quintanilla, B. P., Ayanore, M. A., Ayele, H. T., Babaee, E., Bacha, U., Badawi, A., Bagherzadeh, M., Bagli, E., Balakrishnan, S., Balouchi, A., Bärnighausen, T. W., Battista, R. J., Behzadifar, M., Bekele, B. B., Belay, Y. B., Belayneh, Y. M., Berfield, K. K. S., Berhane, A., Bernabe, E., Beuran, M., Bhakta, N., Bhattacharyya, K., Biadgo, B., Bijani, A., Bin Sayeed, M. S., Birungi, C., Bisignano, C., Bitew, H., Bjørge, T., Bleyer, A., Bogale, K. A., Bojia, H. A., Borzì, A. M., Bosetti, C., Bou-Orm, I. R., Brenner, H., Brewer, J. D., Briko, A. N., Briko, N. I., Bustamante-Teixeira, M. T., Butt, Z. A., Carreras, G., Carrero, J. J., Carvalho, F., Castro, C., Castro, F., Catalá-López, F., Cerin, E., Chaiah, Y., Chanie, W. F., Chattu, V. K., Chaturvedi, P., Chauhan, N. S., Chehrazi, M., Chiang, P. P. -C, Chichiabellu, T. Y., Chido-Amajuoyi, O. G., Chimed-Ochir, O., Choi, J. -YJ., Christopher, D. J., Chu, D. -T, Constantin, M. -M, Costa, V. M., Crocetti, E., Crowe, C. S., Curado, M. P., Dahlawi, S. M. A., Damiani, G., Darwish, A. H., Daryani, A., Das Neves, J., Demeke, F. M., Demis, A. B., Demissie, B. W., Demoz, G. T., Denova-Gutiérrez, E., Derakhshani, A., Deribe, K. S., Desai, R., Desalegn, B. B., Desta, M., Dey, S., Dharmaratne, S. D., Dhimal, M., Diaz, D., Dinberu, M. T. T., Djalalinia, S., Doku, D. T., Drake, T. M., Dubey, M., Dubljanin, E., Duken, E. E., Ebrahimi, H., Effiong, A., Eftekhari, A., El Sayed, I., Zaki, M. E. S., El-Jaafary, S. I., El-Khatib, Z., Elemineh, D. A., Elkout, H., Ellenbogen, R. G., Elsharkawy, A., Emamian, M. H., Endalew, D. A., Endries, A. Y., Eshrati, B., Fadhil, I., Fallah, V., Faramarzi, M., Farhangi, M. A., Farioli, A., Farzadfar, F., Fentahun, N., Fernandes, E., Feyissa, G. T., Filip, I., Fischer, F., Fisher, J. L., Force, L. M., Foroutan, M., Freitas, M., Fukumoto, T., Futran, N. D., Gallus, S., Gankpe, F. G., Gayesa, R. T., Gebrehiwot, T. T., Gebremeskel, G. G., Gedefaw, G. A., Gelaw, B. K., Geta, B., Getachew, S., Gezae, K. E., Ghafourifard, M., Ghajar, A., Ghashghaee, A., Gholamian, A., Gill, P. S., Ginindza, T. T. G., Girmay, A., Gizaw, M., Gomez, R. S., Gopalani, S. V., Gorini, G., Goulart, B. N. G., Grada, A., Ribeiro Guerra, M., Guimaraes, A. L. S., Gupta, P. C., Gupta, R., Hadkhale, K., Haj-Mirzaian, A., Hamadeh, R. R., Hamidi, S., Hanfore, L. K., Haro, J. M., Hasankhani, M., Hasanzadeh, A., Hassen, H. Y., Hay, R. J., Hay, S. I., Henok, A., Henry, N. J., Herteliu, C., Hidru, H. D., Hoang, C. L., Hole, M. K., Hoogar, P., Horita, N., Hosgood, H. D., Hosseini, M., Hosseinzadeh, M., Hostiuc, M., Hostiuc, S., Househ, M., Hussen, M. M., Ileanu, B., Ilic, M. D., Innos, K., Irvani, S. S. N., Iseh, K. R., Islam, S. M. S., Islami, F., Jafari Balalami, N., Jafarinia, M., Jahangiry, L., Jahani, M. A., Jahanmehr, N., Jakovljevic, M., James, S. L., Javanbakht, M., Jayaraman, S., Jee, S. H., Jenabi, E., Jha, R. P., Jonas, J. B., Jonnagaddala, J., Joo, T., Jungari, S. B., Jürisson, M., Kabir, A., Kamangar, F., Karch, A., Karimi, N., Karimian, A., Kasaeian, A., Kasahun, G. G., Kassa, B., Kassa, T. D., Kassaw, M. W., Kaul, A., Keiyoro, P. N., Kelbore, A. G., Kerbo, A. A., Khader, Y. S., Khalilarjmandi, M., Khan, E. A., Khan, G., Khang, Y. -H, Khatab, K., Khater, A., Khayamzadeh, M., Khazaee-Pool, M., Khazaei, S., Khoja, A. T., Khosravi, M. H., Khubchandani, J., Kianipour, N., Kim, D., Kim, Y. J., Kisa, A., Kisa, S., Kissimova-Skarbek, K., Komaki, H., Koyanagi, A., Krohn, K. J., Bicer, B. K., Kugbey, N., Kumar, V., Kuupiel, D., La Vecchia, C., Lad, D. P., Lake, E. A., Lakew, A. M., Lal, D. K., Lami, F. H., Lan, Q., Lasrado, S., Lauriola, P., Lazarus, J. V., Leigh, J., Leshargie, C. T., Liao, Y., Limenih, M. A., Listl, S., Lopez, A. D., Lopukhov, P. D., Lunevicius, R., Madadin, M., Magdeldin, S., El Razek, H. M. A., Majeed, A., Maleki, A., Malekzadeh, R., Manafi, A., Manafi, N., Manamo, W. A., Mansourian, M., Mansournia, M. A., Mantovani, L. G., Maroufizadeh, S., Martini, S. M. S., Mashamba-Thompson, T. P., Massenburg, B. B., Maswabi, M. T., Mathur, M. R., McAlinden, C., McKee, M., Meheretu, H. A. A., Mehrotra, R., Mehta, V., Meier, T., Melaku, Y. A., Meles, G. G., Meles, H. G., Melese, A., Melku, M., Memiah, P. T. N., Mendoza, W., Menezes, R. G., Merat, S., Meretoja, T. J., Mestrovic, T., Miazgowski, B., Miazgowski, T., Mihretie, K. M. M., Miller, T. R., Mills, E. J., Mir, S. M., Mirzaei, H., Mirzaei, H. R., Mishra, R., Moazen, B., Mohammad, D. K., Mohammad, K. A., Mohammad, Y., Darwesh, A. M., Mohammadbeigi, A., Mohammadi, H., Mohammadi, M., Mohammadian, M., Mohammadian-Hafshejani, A., Mohammadoo-Khorasani, M., Mohammadpourhodki, R., Mohammed, A. S., Mohammed, J. A., Mohammed, S., Mohebi, F., Mokdad, A. H., Monasta, L., Moodley, Y., Moosazadeh, M., Moossavi, M., Moradi, G., Moradi-Joo, M., Moradi-Lakeh, M., Moradpour, F., Morawska, L., Morgado-Da-Costa, J., Morisaki, N., Morrison, S. D., Mosapour, A., Mousavi, S. M., Muche, A. A., Muhammed, O. S. S., Musa, J., Nabhan, A. R., Naderi, M., Nagarajan, A. J., Nagel, G., Nahvijou, A., Naik, G., Najafi, F., Naldi, L., Nam, H. S., Nasiri, N., Nazari, J., Negoi, I., Neupane, S., Newcomb, P. A., Nggada, H. A., Ngunjiri, J. W., Nguyen, C. T., Nikniaz, L., Ningrum, D. N. A., Nirayo, Y. L., Nixon, M. R., Nnaji, C. A., Nojomi, M., Nosratnejad, S., Shiadeh, M. N., Obsa, M. S., Ofori-Asenso, R., Ogbo, F. A., Oh, I. -H, Olagunju, A. T., Olagunju, T. O., Oluwasanu, M. M., Omonisi, A. E., Onwujekwe, O. E., Oommen, A. M., Oren, E., Ortega-Altamirano, D. D. V., Ota, E., Otstavnov, S. S., Owolabi, M. O., Mahesh, P. A., Padubidri, J. R., Pakhale, S., Pakpour, Amir H., Pana, A., Park, E. -K, Parsian, H., Pashaei, T., Patel, S., Patil, S. T., Pennini, A., Pereira, D. M., Piccinelli, C., Pillay, J. D., Pirestani, M., Pishgar, F., Postma, M. J., Pourjafar, H., Pourmalek, F., Pourshams, A., Prakash, S., Prasad, N., Qorbani, M., Rabiee, M., Rabiee, N., Radfar, A., Rafiei, A., Rahim, F., Rahimi, M., Rahman, M. A., Rajati, F., Rana, S. M., Raoofi, S., Rath, G. K., Rawaf, D. L., Rawaf, S., Reiner, R. C., Renzaho, A. M. N., Rezaei, N., Rezapour, A., Ribeiro, A. I., Ribeiro, D., Ronfani, L., Roro, E. M., Roshandel, G., Rostami, A., Saad, R. S., Sabbagh, P., Sabour, S., Saddik, B., Safiri, S., Sahebkar, A., Salahshoor, M. R., Salehi, F., Salem, H., Salem, M. R., Salimzadeh, H., Salomon, J. A., Samy, A. M., Sanabria, J., Santric Milicevic, M. M., Sartorius, B., Sarveazad, A., Sathian, B., Satpathy, M., Savic, M., Sawhney, M., Sayyah, M., Schneider, I. J. C., Schöttker, B., Sekerija, M., Sepanlou, S. G., Sepehrimanesh, M., Seyedmousavi, S., Shaahmadi, F., Shabaninejad, H., Shahbaz, M., Shaikh, M. A., Shamshirian, A., Shamsizadeh, M., Sharafi, H., Sharafi, Z., Sharif, M., Sharifi, A., Sharifi, H., Sharma, R., Sheikh, A., Shirkoohi, R., Shukla, S. R., Si, S., Siabani, S., Silva, D. A. S., Silveira, D. G. A., Singh, A., Singh, J. A., Sisay, S., Sitas, F., Sobngwi, E., Soofi, M., Soriano, J. B., Stathopoulou, V., Sufiyan, M. B., Tabarés-Seisdedos, R., Tabuchi, T., Takahashi, K., Tamtaji, O. R., Tarawneh, M. R., Tassew, S. G., Taymoori, P., Tehrani-Banihashemi, A., Temsah, M. -H, Temsah, O., Tesfay, B. E., Tesfay, F. H., Teshale, M. Y., Tessema, G. A., Thapa, S., Tlaye, K. G., Topor-Madry, R., Tovani-Palone, M. R., Traini, E., Tran, B. X., Tran, K. B., Tsadik, A. G., Ullah, I., Uthman, O. A., Vacante, M., Vaezi, M., Varona Pérez, P., Veisani, Y., Vidale, S., Violante, F. S., Vlassov, V., Vollset, S. E., Vos, T., Vosoughi, K., Vu, G. T., Vujcic, I. S., Wabinga, H., Wachamo, T. M., Wagnew, F. S., Waheed, Y., Weldegebreal, F., Weldesamuel, G. T., Wijeratne, T., Wondafrash, D. 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Abstract: Importance: Cancer and other noncommunicable diseases (NCDs) are now widely recognized as a threat to global development. The latest United Nations high-level meeting on NCDs reaffirmed this observation and also highlighted the slow progress in meeting the 2011 Political Declaration on the Prevention and Control of Noncommunicable Diseases and the third Sustainable Development Goal. Lack of situational analyses, priority setting, and budgeting have been identified as major obstacles in achieving these goals. All of these have in common that they require information on the local cancer epidemiology. The Global Burden of Disease (GBD) study is uniquely poised to provide these crucial data. Objective: To describe cancer burden for 29 cancer groups in 195 countries from 1990 through 2017 to provide data needed for cancer control planning. Evidence Review: We used the GBD study estimation methods to describe cancer incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life-years (DALYs). Results are presented at the national level as well as by Socio-demographic Index (SDI), a composite indicator of income, educational attainment, and total fertility rate. We also analyzed the influence of the epidemiological vs the demographic transition on cancer incidence. Findings: In 2017, there were 24.5 million incident cancer cases worldwide (16.8 million without nonmelanoma skin cancer [NMSC]) and 9.6 million cancer deaths. The majority of cancer DALYs came from years of life lost (97%), and only 3% came from years lived with disability. The odds of developing cancer were the lowest in the low SDI quintile (1 in 7) and the highest in the high SDI quintile (1 in 2) for both sexes. In 2017, the most common incident cancers in men were NMSC (4.3 million incident cases); tracheal, bronchus, and lung (TBL) cancer (1.5 million incident cases); and prostate cancer (1.3 million incident cases). The most common causes of cancer deaths and DALYs fo
Published: 2019
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17. Alcohol use and burden for 195 countries and territories, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016.

Author: Shen J., Sorensen R.J.D., Soriano J.B., Sreeramareddy C.T., Steckling N., Stein D.J., Sufiyan M.B., Sur P.J., Sykes B.L., Tabares-Seisdedos R., Tabuchi T., Tavakkoli M., Tehrani-Banihashemi A., Tekle M.G., Thapa S., Thomas N., Topor-Madry R., Topouzis F., Tran B.X., Troeger C.E., Truelsen T.C., Tsilimparis N., Tyrovolas S., Ukwaja K.N., Ullah I., Uthman O.A., Valdez P.R., Van Boven J.F.M., Vasankari T.J., Venketasubramanian N., Violante F.S., Vladimirov S.K., Vlassov V., Vollset S.E., Vos T., Wagnew F.W.S., Waheed Y., Wang Y.-P., Weiderpass E., Weldegebreal F., Weldegwergs K.G., Werdecker A., Westerman R., Whiteford H.A., Widecka J., Wijeratne T., Wyper G.M.A., Xu G., Yamada T., Yano Y., Ye P., Yimer E.M., Yip P., Yirsaw B.D., Yisma E., Yonemoto N., Yoon S.-J., Yotebieng M., Younis M.Z., Zachariah G., Zaidi Z., Zamani M., Zhang X., Zodpey S., Mokdad A.H., Naghavi M., Murray C.J.L., Gakidou E., Griswold M.G., Fullman N., Hawley C., Arian N., Zimsen S.R.M., Tymeson H.D., 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T., Bhaumik S., Bhutta Z.A., Biadgo B., Bijani A., Bililign N., Birlik S.M., Birungi C., Bizuneh H., Bjerregaard P., Bjorge T., Borges G., Bosetti C., Boufous S., Bragazzi N.L., Brenner H., Butt Z.A., Cahuana-Hurtado L., Calabria B., Campos-Nonato I.R., Rincon J.C.C., Carreras G., Carrero J.J., Carvalho F., Castaneda-Orjuela C.A., Rivas J.C., Catala-Lopez F., Chang J.-C., Charlson F.J., Chattopadhyay A., Chaturvedi P., Chowdhury R., Christopher D.J., Chung S.-C., Ciobanu L.G., Claro R.M., Conti S., Cousin E., Criqui M.H., Dachew B.A., Dargan P.I., Daryani A., Das Neves J., Davletov K., De Castro F., De Courten B., De Neve J.-W., Degenhardt L., Demoz G.T., Des Jarlais D.C., Dey S., Dhaliwal R.S., Dharmaratne S.D., Dhimal M., Doku D.T., Doyle K.E., Dubey M., Dubljanin E., Duncan B.B., Ebrahimi H., Edessa D., El Sayed Zaki M., Ermakov S.P., Erskine H.E., Esteghamati A., Faramarzi M., Farioli A., Faro A., Farvid M.S., Farzadfar F., Feigin V.L., Felisbino-Mendes M.S., Fernandes E., Ferrari A.J., Ferri C.P., Fijabi D.O., Filip I., Finger J.D., Fischer F., Flaxman A.D., Franklin R.C., Futran N.D., Gallus S., Ganji M., Gankpe F.G., Gebregergs G.B., Gebrehiwot T.T., Geleijnse J.M., Ghadimi R., Ghandour L.A., Ghimire M., Gill P.S., Ginawi I.A., Giref A.Z.Z., Gona P.N., Gopalani S.V., Gotay C.C., Goulart A.C., Greaves F., Grosso G., Guo Y., Gupta R., Gupta V., Gutierrez R.A., Gvs M., Hafezi-Nejad N., Hagos T.B., Hailu G.B., Hamadeh R.R., Hamidi S., Hankey G.J., Harb H.L., Harikrishnan S., Haro J.M., Hassen H.Y., Havmoeller R., Hay S.I., Heibati B., Henok A., Heredia-Pi I., Hernandez-Llanes N.F., Herteliu C., Ts Tsegaw Hibstu D., Hoogar P., Horita N., Hosgood H.D., Hosseini M., Hostiuc M., Hu G., Huang H., Husseini A., Idrisov B., Ileanu B.V., Ilesanmi O.S., Irvani S.S.N., Islam S.M.S., Jackson M.D., Jakovljevic M., Jalu M.T., Jayatilleke A.U., Jha R.P., Jonas J.B., Jozwiak J.J., Kabir Z., Kadel R., Kahsay A., Kapil U., Kasaeian A., Kassa T.D.D., Katikireddi S.V., Kawakami N., Kebede S., Kefale A.T., Keiyoro P.N., Kengne A.P., Khader Y., Khafaie M.A., Khalil I.A., Khan M.N., Khang Y.-H., Khater M.M., Khubchandani J., Kim C.-I., Kim D., Kim Y.J., Kimokoti R.W., Kisa A., Kivimaki M., Kochhar S., Kosen S., Koul P.A., Koyanagi A., Krishan K., Defo B.K., Bicer B.K., Kulkarni V.S., Kumar P., Lafranconi A., Balaji A.L., Lalloo R., Lallukka T., Lam H., Lami F.H., Lan Q., Lang J.J., Lansky S., Larsson A.O., Latifi A., Leasher J.L., Lee P.H., Leigh J., Leinsalu M., Leung J., Levi M., Li Y., Lim L.-L., Linn S., Liu S., Lobato-Cordero A., Lopez A.D., Lotufo P.A., Macarayan E.R.K., Machado I.E., Madotto F., Abd El Razek H.M., Abd El Razek M.M., Majdan M., Majdzadeh R., Majeed A., Malekzadeh R., Malta D.C., Mapoma C.C., Martinez-Raga J., Maulik P.K., Mazidi M., McKee M., Mehta V., Meier T., Mekonen T., Meles K.G., Melese A., Memiah P.T.N., Mendoza W., Mengistu D.T., Mensah G.A., Meretoja T.J., Mezgebe H.B., Miazgowski T., Miller T.R., Mini G., Mirica A., Mirrakhimov E.M., Moazen B., Mohammad K.A., Mohammadifard N., Mohammed S., Monasta L., Moraga P., Morawska L., Mousavi S.M., Mukhopadhyay S., Musa K.I., Naheed A., Naik G., Najafi F., Nangia V., Nansseu J.R., Nayak M.S.D.P., Nejjari C., Neupane S., Neupane S.P., Ngunjiri J.W., Nguyen C.T., Nguyen L.H., Nguyen T.H., Ningrum D.N.A., Nirayo Y.L., Noubiap J.J., Ofori-Asenso R., Ogbo F.A., Oh I.-H., Oladimeji O., Olagunju A.T., Olivares P.R., Olusanya B.O., Olusanya J.O., Oommen A.M., Oren E., Orpana H.M., Ortega-Altamirano D.D.V., Ortiz J.R., Ota E., Owolabi M.O., Oyekale A.S., Mahesh P.A., Pana A., Park E.-K., Parry C.D.H., Parsian H., Patle A., Patton G.C., Paudel D., Petzold M., Phillips M.R., Pillay J.D., Postma M.J., Pourmalek F., Prabhakaran D., Qorbani M., Radfar A., Rafay A., Rafiei A., Rahim F., Rahimi-Movaghar A., Rahman M., Rahman M.A., Rai R.K., Rajsic S., Raju S.B., Ram U., Rana S.M., Ranabhat C.L., Rawaf D.L., Rawaf S., Reiner R.C., Reis C., Renzaho A.M.N., Rezai M.S., Roever L., Ronfani L., Room R., Roshandel G., Rostami A., Roth G.A., Roy A., Sabde Y.D., Saddik B., Safiri S., Sahebkar A., Saleem Z., Salomon J.A., Salvi S.S., Sanabria J., Sanchez-Nino M.D., Santomauro D.F., Santos I.S., Santric Milicevic M.M.M., Sarker A.R., Sarmiento-Suarez R., Sarrafzadegan N., Sartorius B., Satpathy M., Sawhney M., Saxena S., Saylan M., Schaub M.P., Schmidt M.I., Schneider I.J.C., Schottker B., Schutte A.E., Schwendicke F., Sepanlou S.G., Shaikh M.A., Sharif M., She J., Sheikh A., Shiferaw M.S., Shigematsu M., Shiri R., Shishani K., Shiue I., Shukla S.R., Sigfusdottir I.D., Silva D.A.S., Da Silva N.T., Silveira D.G.A., Sinha D.N., Sitas F., Filho A.M.S., Soofi M., Shen J., Sorensen R.J.D., Soriano J.B., Sreeramareddy C.T., Steckling N., Stein D.J., Sufiyan M.B., Sur P.J., Sykes B.L., Tabares-Seisdedos R., Tabuchi T., Tavakkoli M., Tehrani-Banihashemi A., Tekle M.G., Thapa S., Thomas N., Topor-Madry R., Topouzis F., Tran B.X., Troeger C.E., Truelsen T.C., Tsilimparis N., Tyrovolas S., Ukwaja K.N., Ullah I., Uthman O.A., Valdez P.R., Van Boven J.F.M., Vasankari T.J., Venketasubramanian N., Violante F.S., Vladimirov S.K., Vlassov V., Vollset S.E., Vos T., Wagnew F.W.S., Waheed Y., Wang Y.-P., Weiderpass E., Weldegebreal F., Weldegwergs K.G., Werdecker A., Westerman R., Whiteford H.A., Widecka J., Wijeratne T., Wyper G.M.A., Xu G., Yamada T., Yano Y., Ye P., Yimer E.M., Yip P., Yirsaw B.D., Yisma E., Yonemoto N., Yoon S.-J., Yotebieng M., Younis M.Z., Zachariah G., Zaidi Z., Zamani M., Zhang X., Zodpey S., Mokdad A.H., Naghavi M., Murray C.J.L., Gakidou E., Griswold M.G., Fullman N., Hawley C., Arian N., Zimsen S.R.M., Tymeson H.D., Venkateswaran V., Tapp A.D., Forouzanfar M.H., Salama J.S., Abate K.H., Abate D., Abay S.M., Abbafati C., Abdulkader R.S., Abebe Z., Aboyans V., Abrar M.M., Acharya P., Adetokunboh O.O., Adhikari T.B., Adsuar J.C., Afarideh M., Agardh E.E., Agarwal G., Aghayan S.A., Agrawal S., Ahmed M.B., Akibu M., Akinyemiju T., Akseer N., Al Asfoor D.H., Al-Aly Z., Alahdab F., Alam K., Albujeer A., Alene K.A., Ali R., Ali S.D., Alijanzadeh M., Aljunid S.M., Alkerwi A., Allebeck P., Alvis-Guzman N., Amare A.T., Aminde L.N., Ammar W., Amoako Y.A., Amul G.G.H., Andrei C.L., Angus C., Ansha M.G., Antonio C.A.T., Aremu O., Arnlov J., Artaman A., Aryal K.K., Assadi R., Ausloos M., Avila-Burgos L., Avokpaho E.F.G.A., Awasthi A., Ayele H.T., Ayer R., Ayuk T.B., Azzopardi P.S., Badali H., Badawi A., Banach M., Barker-Collo S.L., Barrero L.H., Basaleem H., Baye E., Bazargan-Hejazi S., Bedi N., Bejot Y., Belachew A.B., Belay S.A., Bennett D.A., Bensenor I.M., Bernabe E., Bernstein R.S., Beyene A.S., Beyranvand T., Bhaumik S., Bhutta Z.A., Biadgo B., Bijani A., Bililign N., Birlik S.M., Birungi C., Bizuneh H., Bjerregaard P., Bjorge T., Borges G., Bosetti C., Boufous S., Bragazzi N.L., Brenner H., Butt Z.A., Cahuana-Hurtado L., Calabria B., Campos-Nonato I.R., Rincon J.C.C., Carreras G., Carrero J.J., Carvalho F., Castaneda-Orjuela C.A., Rivas J.C., Catala-Lopez F., Chang J.-C., Charlson F.J., Chattopadhyay A., Chaturvedi P., Chowdhury R., Christopher D.J., Chung S.-C., Ciobanu L.G., Claro R.M., Conti S., Cousin E., Criqui M.H., Dachew B.A., Dargan P.I., Daryani A., Das Neves J., Davletov K., De Castro F., De Courten B., De Neve J.-W., Degenhardt L., Demoz G.T., Des Jarlais D.C., Dey S., Dhaliwal R.S., Dharmaratne S.D., Dhimal M., Doku D.T., Doyle K.E., Dubey M., Dubljanin E., Duncan B.B., Ebrahimi H., Edessa D., El Sayed Zaki M., Ermakov S.P., Erskine H.E., Esteghamati A., Faramarzi M., Farioli A., Faro A., Farvid M.S., Farzadfar F., Feigin V.L., Felisbino-Mendes M.S., Fernandes E., Ferrari A.J., Ferri C.P., Fijabi D.O., Filip I., Finger J.D., Fischer F., Flaxman A.D., Franklin R.C., Futran N.D., Gallus S., Ganji M., Gankpe F.G., Gebregergs G.B., Gebrehiwot T.T., Geleijnse J.M., Ghadimi R., Ghandour L.A., Ghimire M., Gill P.S., Ginawi I.A., Giref A.Z.Z., Gona P.N., Gopalani S.V., Gotay C.C., Goulart A.C., Greaves F., Grosso G., Guo Y., Gupta R., Gupta V., Gutierrez R.A., Gvs M., Hafezi-Nejad N., Hagos T.B., Hailu G.B., Hamadeh R.R., Hamidi S., Hankey G.J., Harb H.L., Harikrishnan S., Haro J.M., Hassen H.Y., Havmoeller R., Hay S.I., Heibati B., Henok A., Heredia-Pi I., Hernandez-Llanes N.F., Herteliu C., Ts Tsegaw Hibstu D., Hoogar P., Horita N., Hosgood H.D., Hosseini M., Hostiuc M., Hu G., Huang H., Husseini A., Idrisov B., Ileanu B.V., Ilesanmi O.S., Irvani S.S.N., Islam S.M.S., Jackson M.D., Jakovljevic M., Jalu M.T., Jayatilleke A.U., Jha R.P., Jonas J.B., Jozwiak J.J., Kabir Z., Kadel R., Kahsay A., Kapil U., Kasaeian A., Kassa T.D.D., Katikireddi S.V., Kawakami N., Kebede S., Kefale A.T., Keiyoro P.N., Kengne A.P., Khader Y., Khafaie M.A., Khalil I.A., Khan M.N., Khang Y.-H., Khater M.M., Khubchandani J., Kim C.-I., Kim D., Kim Y.J., Kimokoti R.W., Kisa A., Kivimaki M., Kochhar S., Kosen S., Koul P.A., Koyanagi A., Krishan K., Defo B.K., Bicer B.K., Kulkarni V.S., Kumar P., Lafranconi A., Balaji A.L., Lalloo R., Lallukka T., Lam H., Lami F.H., Lan Q., Lang J.J., Lansky S., Larsson A.O., Latifi A., Leasher J.L., Lee P.H., Leigh J., Leinsalu M., Leung J., Levi M., Li Y., Lim L.-L., Linn S., Liu S., Lobato-Cordero A., Lopez A.D., Lotufo P.A., Macarayan E.R.K., Machado I.E., Madotto F., Abd El Razek H.M., Abd El Razek M.M., Majdan M., Majdzadeh R., Majeed A., Malekzadeh R., Malta D.C., Mapoma C.C., Martinez-Raga J., Maulik P.K., Mazidi M., McKee M., Mehta V., Meier T., Mekonen T., Meles K.G., Melese A., Memiah P.T.N., Mendoza W., Mengistu D.T., Mensah G.A., Meretoja T.J., Mezgebe H.B., Miazgowski T., Miller T.R., Mini G., Mirica A., Mirrakhimov E.M., Moazen B., Mohammad K.A., Mohammadifard N., Mohammed S., Monasta L., Moraga P., Morawska L., Mousavi S.M., Mukhopadhyay S., Musa K.I., Naheed A., Naik G., Najafi F., Nangia V., Nansseu J.R., Nayak M.S.D.P., Nejjari C., Neupane S., Neupane S.P., Ngunjiri J.W., Nguyen C.T., Nguyen L.H., Nguyen T.H., Ningrum D.N.A., Nirayo Y.L., Noubiap J.J., Ofori-Asenso R., Ogbo F.A., Oh I.-H., Oladimeji O., Olagunju A.T., Olivares P.R., Olusanya B.O., Olusanya J.O., Oommen A.M., Oren E., Orpana H.M., Ortega-Altamirano D.D.V., Ortiz J.R., Ota E., Owolabi M.O., Oyekale A.S., Mahesh P.A., Pana A., Park E.-K., Parry C.D.H., Parsian H., Patle A., Patton G.C., Paudel D., Petzold M., Phillips M.R., Pillay J.D., Postma M.J., Pourmalek F., Prabhakaran D., Qorbani M., Radfar A., Rafay A., Rafiei A., Rahim F., Rahimi-Movaghar A., Rahman M., Rahman M.A., Rai R.K., Rajsic S., Raju S.B., Ram U., Rana S.M., Ranabhat C.L., Rawaf D.L., Rawaf S., Reiner R.C., Reis C., Renzaho A.M.N., Rezai M.S., Roever L., Ronfani L., Room R., Roshandel G., Rostami A., Roth G.A., Roy A., Sabde Y.D., Saddik B., Safiri S., Sahebkar A., Saleem Z., Salomon J.A., Salvi S.S., Sanabria J., Sanchez-Nino M.D., Santomauro D.F., Santos I.S., Santric Milicevic M.M.M., Sarker A.R., Sarmiento-Suarez R., Sarrafzadegan N., Sartorius B., Satpathy M., Sawhney M., Saxena S., Saylan M., Schaub M.P., Schmidt M.I., Schneider I.J.C., Schottker B., Schutte A.E., Schwendicke F., Sepanlou S.G., Shaikh M.A., Sharif M., She J., Sheikh A., Shiferaw M.S., Shigematsu M., Shiri R., Shishani K., Shiue I., Shukla S.R., Sigfusdottir I.D., Silva D.A.S., Da Silva N.T., Silveira D.G.A., Sinha D.N., Sitas F., Filho A.M.S., and Soofi M.
Abstract: Background: Alcohol use is a leading risk factor for death and disability, but its overall association with health remains complex given the possible protective effects of moderate alcohol consumption on some conditions. With our comprehensive approach to health accounting within the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we generated improved estimates of alcohol use and alcohol-attributable deaths and disability-adjusted lifeyears (DALYs) for 195 locations from 1990 to 2016, for both sexes and for 5-year age groups between the ages of 15 years and 95 years and older. Method(s): Using 694 data sources of individual and population-level alcohol consumption, along with 592 prospective and retrospective studies on the risk of alcohol use, we produced estimates of the prevalence of current drinking, abstention, the distribution of alcohol consumption among current drinkers in standard drinks daily (defined as 10 g of pure ethyl alcohol), and alcohol-attributable deaths and DALYs. We made several methodological improvements compared with previous estimates: first, we adjusted alcohol sales estimates to take into account tourist and unrecorded consumption; second, we did a new meta-analysis of relative risks for 23 health outcomes associated with alcohol use; and third, we developed a new method to quantify the level of alcohol consumption that minimises the overall risk to individual health. Finding(s): Globally, alcohol use was the seventh leading risk factor for both deaths and DALYs in 2016, accounting for 2.2% (95% uncertainty interval [UI] 1.5-3.0) of age-standardised female deaths and 6.8% (5.8-8.0) of agestandardised male deaths. Among the population aged 15-49 years, alcohol use was the leading risk factor globally in 2016, with 3.8% (95% UI 3.2-4.3) of female deaths and 12.2% (10.8-13.6) of male deaths attributable to alcohol use. For the population aged 15-49 years, female attributable DALYs were 2.3% (95% UI 2.0-2.6) and male attrib
Published: 2018

18. Alcohol use and burden for 195 countries and territories, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016.

Author: Shen J., Sorensen R.J.D., Soriano J.B., Sreeramareddy C.T., Steckling N., Stein D.J., Sufiyan M.B., Sur P.J., Sykes B.L., Tabares-Seisdedos R., Tabuchi T., Tavakkoli M., Tehrani-Banihashemi A., Tekle M.G., Thapa S., Thomas N., Topor-Madry R., Topouzis F., Tran B.X., Troeger C.E., Truelsen T.C., Tsilimparis N., Tyrovolas S., Ukwaja K.N., Ullah I., Uthman O.A., Valdez P.R., Van Boven J.F.M., Vasankari T.J., Venketasubramanian N., Violante F.S., Vladimirov S.K., Vlassov V., Vollset S.E., Vos T., Wagnew F.W.S., Waheed Y., Wang Y.-P., Weiderpass E., Weldegebreal F., Weldegwergs K.G., Werdecker A., Westerman R., Whiteford H.A., Widecka J., Wijeratne T., Wyper G.M.A., Xu G., Yamada T., Yano Y., Ye P., Yimer E.M., Yip P., Yirsaw B.D., Yisma E., Yonemoto N., Yoon S.-J., Yotebieng M., Younis M.Z., Zachariah G., Zaidi Z., Zamani M., Zhang X., Zodpey S., Mokdad A.H., Naghavi M., Murray C.J.L., Gakidou E., Griswold M.G., Fullman N., Hawley C., Arian N., Zimsen S.R.M., Tymeson H.D., Venkateswaran V., Tapp A.D., Forouzanfar M.H., Salama J.S., Abate K.H., Abate D., Abay S.M., Abbafati C., Abdulkader R.S., Abebe Z., Aboyans V., Abrar M.M., Acharya P., Adetokunboh O.O., Adhikari T.B., Adsuar J.C., Afarideh M., Agardh E.E., Agarwal G., Aghayan S.A., Agrawal S., Ahmed M.B., Akibu M., Akinyemiju T., Akseer N., Al Asfoor D.H., Al-Aly Z., Alahdab F., Alam K., Albujeer A., Alene K.A., Ali R., Ali S.D., Alijanzadeh M., Aljunid S.M., Alkerwi A., Allebeck P., Alvis-Guzman N., Amare A.T., Aminde L.N., Ammar W., Amoako Y.A., Amul G.G.H., Andrei C.L., Angus C., Ansha M.G., Antonio C.A.T., Aremu O., Arnlov J., Artaman A., Aryal K.K., Assadi R., Ausloos M., Avila-Burgos L., Avokpaho E.F.G.A., Awasthi A., Ayele H.T., Ayer R., Ayuk T.B., Azzopardi P.S., Badali H., Badawi A., Banach M., Barker-Collo S.L., Barrero L.H., Basaleem H., Baye E., Bazargan-Hejazi S., Bedi N., Bejot Y., Belachew A.B., Belay S.A., Bennett D.A., Bensenor I.M., Bernabe E., Bernstein R.S., Beyene A.S., Beyranvand T., Bhaumik S., Bhutta Z.A., Biadgo B., Bijani A., Bililign N., Birlik S.M., Birungi C., Bizuneh H., Bjerregaard P., Bjorge T., Borges G., Bosetti C., Boufous S., Bragazzi N.L., Brenner H., Butt Z.A., Cahuana-Hurtado L., Calabria B., Campos-Nonato I.R., Rincon J.C.C., Carreras G., Carrero J.J., Carvalho F., Castaneda-Orjuela C.A., Rivas J.C., Catala-Lopez F., Chang J.-C., Charlson F.J., Chattopadhyay A., Chaturvedi P., Chowdhury R., Christopher D.J., Chung S.-C., Ciobanu L.G., Claro R.M., Conti S., Cousin E., Criqui M.H., Dachew B.A., Dargan P.I., Daryani A., Das Neves J., Davletov K., De Castro F., De Courten B., De Neve J.-W., Degenhardt L., Demoz G.T., Des Jarlais D.C., Dey S., Dhaliwal R.S., Dharmaratne S.D., Dhimal M., Doku D.T., Doyle K.E., Dubey M., Dubljanin E., Duncan B.B., Ebrahimi H., Edessa D., El Sayed Zaki M., Ermakov S.P., Erskine H.E., Esteghamati A., Faramarzi M., Farioli A., Faro A., Farvid M.S., Farzadfar F., Feigin V.L., Felisbino-Mendes M.S., Fernandes E., Ferrari A.J., Ferri C.P., Fijabi D.O., Filip I., Finger J.D., Fischer F., Flaxman A.D., Franklin R.C., Futran N.D., Gallus S., Ganji M., Gankpe F.G., Gebregergs G.B., Gebrehiwot T.T., Geleijnse J.M., Ghadimi R., Ghandour L.A., Ghimire M., Gill P.S., Ginawi I.A., Giref A.Z.Z., Gona P.N., Gopalani S.V., Gotay C.C., Goulart A.C., Greaves F., Grosso G., Guo Y., Gupta R., Gupta V., Gutierrez R.A., Gvs M., Hafezi-Nejad N., Hagos T.B., Hailu G.B., Hamadeh R.R., Hamidi S., Hankey G.J., Harb H.L., Harikrishnan S., Haro J.M., Hassen H.Y., Havmoeller R., Hay S.I., Heibati B., Henok A., Heredia-Pi I., Hernandez-Llanes N.F., Herteliu C., Ts Tsegaw Hibstu D., Hoogar P., Horita N., Hosgood H.D., Hosseini M., Hostiuc M., Hu G., Huang H., Husseini A., Idrisov B., Ileanu B.V., Ilesanmi O.S., Irvani S.S.N., Islam S.M.S., Jackson M.D., Jakovljevic M., Jalu M.T., Jayatilleke A.U., Jha R.P., Jonas J.B., Jozwiak J.J., Kabir Z., Kadel R., Kahsay A., Kapil U., Kasaeian A., Kassa T.D.D., Katikireddi S.V., Kawakami N., Kebede S., Kefale A.T., Keiyoro P.N., Kengne A.P., Khader Y., Khafaie M.A., Khalil I.A., Khan M.N., Khang Y.-H., Khater M.M., Khubchandani J., Kim C.-I., Kim D., Kim Y.J., Kimokoti R.W., Kisa A., Kivimaki M., Kochhar S., Kosen S., Koul P.A., Koyanagi A., Krishan K., Defo B.K., Bicer B.K., Kulkarni V.S., Kumar P., Lafranconi A., Balaji A.L., Lalloo R., Lallukka T., Lam H., Lami F.H., Lan Q., Lang J.J., Lansky S., Larsson A.O., Latifi A., Leasher J.L., Lee P.H., Leigh J., Leinsalu M., Leung J., Levi M., Li Y., Lim L.-L., Linn S., Liu S., Lobato-Cordero A., Lopez A.D., Lotufo P.A., Macarayan E.R.K., Machado I.E., Madotto F., Abd El Razek H.M., Abd El Razek M.M., Majdan M., Majdzadeh R., Majeed A., Malekzadeh R., Malta D.C., Mapoma C.C., Martinez-Raga J., Maulik P.K., Mazidi M., McKee M., Mehta V., Meier T., Mekonen T., Meles K.G., Melese A., Memiah P.T.N., Mendoza W., Mengistu D.T., Mensah G.A., Meretoja T.J., Mezgebe H.B., Miazgowski T., Miller T.R., Mini G., Mirica A., Mirrakhimov E.M., Moazen B., Mohammad K.A., Mohammadifard N., Mohammed S., Monasta L., Moraga P., Morawska L., Mousavi S.M., Mukhopadhyay S., Musa K.I., Naheed A., Naik G., Najafi F., Nangia V., Nansseu J.R., Nayak M.S.D.P., Nejjari C., Neupane S., Neupane S.P., Ngunjiri J.W., Nguyen C.T., Nguyen L.H., Nguyen T.H., Ningrum D.N.A., Nirayo Y.L., Noubiap J.J., Ofori-Asenso R., Ogbo F.A., Oh I.-H., Oladimeji O., Olagunju A.T., Olivares P.R., Olusanya B.O., Olusanya J.O., Oommen A.M., Oren E., Orpana H.M., Ortega-Altamirano D.D.V., Ortiz J.R., Ota E., Owolabi M.O., Oyekale A.S., Mahesh P.A., Pana A., Park E.-K., Parry C.D.H., Parsian H., Patle A., Patton G.C., Paudel D., Petzold M., Phillips M.R., Pillay J.D., Postma M.J., Pourmalek F., Prabhakaran D., Qorbani M., Radfar A., Rafay A., Rafiei A., Rahim F., Rahimi-Movaghar A., Rahman M., Rahman M.A., Rai R.K., Rajsic S., Raju S.B., Ram U., Rana S.M., Ranabhat C.L., Rawaf D.L., Rawaf S., Reiner R.C., Reis C., Renzaho A.M.N., Rezai M.S., Roever L., Ronfani L., Room R., Roshandel G., Rostami A., Roth G.A., Roy A., Sabde Y.D., Saddik B., Safiri S., Sahebkar A., Saleem Z., Salomon J.A., Salvi S.S., Sanabria J., Sanchez-Nino M.D., Santomauro D.F., Santos I.S., Santric Milicevic M.M.M., Sarker A.R., Sarmiento-Suarez R., Sarrafzadegan N., Sartorius B., Satpathy M., Sawhney M., Saxena S., Saylan M., Schaub M.P., Schmidt M.I., Schneider I.J.C., Schottker B., Schutte A.E., Schwendicke F., Sepanlou S.G., Shaikh M.A., Sharif M., She J., Sheikh A., Shiferaw M.S., Shigematsu M., Shiri R., Shishani K., Shiue I., Shukla S.R., Sigfusdottir I.D., Silva D.A.S., Da Silva N.T., Silveira D.G.A., Sinha D.N., Sitas F., Filho A.M.S., Soofi M., Shen J., Sorensen R.J.D., Soriano J.B., Sreeramareddy C.T., Steckling N., Stein D.J., Sufiyan M.B., Sur P.J., Sykes B.L., Tabares-Seisdedos R., Tabuchi T., Tavakkoli M., Tehrani-Banihashemi A., Tekle M.G., Thapa S., Thomas N., Topor-Madry R., Topouzis F., Tran B.X., Troeger C.E., Truelsen T.C., Tsilimparis N., Tyrovolas S., Ukwaja K.N., Ullah I., Uthman O.A., Valdez P.R., Van Boven J.F.M., Vasankari T.J., Venketasubramanian N., Violante F.S., Vladimirov S.K., Vlassov V., Vollset S.E., Vos T., Wagnew F.W.S., Waheed Y., Wang Y.-P., Weiderpass E., Weldegebreal F., Weldegwergs K.G., Werdecker A., Westerman R., Whiteford H.A., Widecka J., Wijeratne T., Wyper G.M.A., Xu G., Yamada T., Yano Y., Ye P., Yimer E.M., Yip P., Yirsaw B.D., Yisma E., Yonemoto N., Yoon S.-J., Yotebieng M., Younis M.Z., Zachariah G., Zaidi Z., Zamani M., Zhang X., Zodpey S., Mokdad A.H., Naghavi M., Murray C.J.L., Gakidou E., Griswold M.G., Fullman N., Hawley C., Arian N., Zimsen S.R.M., Tymeson H.D., Venkateswaran V., Tapp A.D., Forouzanfar M.H., Salama J.S., Abate K.H., Abate D., Abay S.M., Abbafati C., Abdulkader R.S., Abebe Z., Aboyans V., Abrar M.M., Acharya P., Adetokunboh O.O., Adhikari T.B., Adsuar J.C., Afarideh M., Agardh E.E., Agarwal G., Aghayan S.A., Agrawal S., Ahmed M.B., Akibu M., Akinyemiju T., Akseer N., Al Asfoor D.H., Al-Aly Z., Alahdab F., Alam K., Albujeer A., Alene K.A., Ali R., Ali S.D., Alijanzadeh M., Aljunid S.M., Alkerwi A., Allebeck P., Alvis-Guzman N., Amare A.T., Aminde L.N., Ammar W., Amoako Y.A., Amul G.G.H., Andrei C.L., Angus C., Ansha M.G., Antonio C.A.T., Aremu O., Arnlov J., Artaman A., Aryal K.K., Assadi R., Ausloos M., Avila-Burgos L., Avokpaho E.F.G.A., Awasthi A., Ayele H.T., Ayer R., Ayuk T.B., Azzopardi P.S., Badali H., Badawi A., Banach M., Barker-Collo S.L., Barrero L.H., Basaleem H., Baye E., Bazargan-Hejazi S., Bedi N., Bejot Y., Belachew A.B., Belay S.A., Bennett D.A., Bensenor I.M., Bernabe E., Bernstein R.S., Beyene A.S., Beyranvand T., Bhaumik S., Bhutta Z.A., Biadgo B., Bijani A., Bililign N., Birlik S.M., Birungi C., Bizuneh H., Bjerregaard P., Bjorge T., Borges G., Bosetti C., Boufous S., Bragazzi N.L., Brenner H., Butt Z.A., Cahuana-Hurtado L., Calabria B., Campos-Nonato I.R., Rincon J.C.C., Carreras G., Carrero J.J., Carvalho F., Castaneda-Orjuela C.A., Rivas J.C., Catala-Lopez F., Chang J.-C., Charlson F.J., Chattopadhyay A., Chaturvedi P., Chowdhury R., Christopher D.J., Chung S.-C., Ciobanu L.G., Claro R.M., Conti S., Cousin E., Criqui M.H., Dachew B.A., Dargan P.I., Daryani A., Das Neves J., Davletov K., De Castro F., De Courten B., De Neve J.-W., Degenhardt L., Demoz G.T., Des Jarlais D.C., Dey S., Dhaliwal R.S., Dharmaratne S.D., Dhimal M., Doku D.T., Doyle K.E., Dubey M., Dubljanin E., Duncan B.B., Ebrahimi H., Edessa D., El Sayed Zaki M., Ermakov S.P., Erskine H.E., Esteghamati A., Faramarzi M., Farioli A., Faro A., Farvid M.S., Farzadfar F., Feigin V.L., Felisbino-Mendes M.S., Fernandes E., Ferrari A.J., Ferri C.P., Fijabi D.O., Filip I., Finger J.D., Fischer F., Flaxman A.D., Franklin R.C., Futran N.D., Gallus S., Ganji M., Gankpe F.G., Gebregergs G.B., Gebrehiwot T.T., Geleijnse J.M., Ghadimi R., Ghandour L.A., Ghimire M., Gill P.S., Ginawi I.A., Giref A.Z.Z., Gona P.N., Gopalani S.V., Gotay C.C., Goulart A.C., Greaves F., Grosso G., Guo Y., Gupta R., Gupta V., Gutierrez R.A., Gvs M., Hafezi-Nejad N., Hagos T.B., Hailu G.B., Hamadeh R.R., Hamidi S., Hankey G.J., Harb H.L., Harikrishnan S., Haro J.M., Hassen H.Y., Havmoeller R., Hay S.I., Heibati B., Henok A., Heredia-Pi I., Hernandez-Llanes N.F., Herteliu C., Ts Tsegaw Hibstu D., Hoogar P., Horita N., Hosgood H.D., Hosseini M., Hostiuc M., Hu G., Huang H., Husseini A., Idrisov B., Ileanu B.V., Ilesanmi O.S., Irvani S.S.N., Islam S.M.S., Jackson M.D., Jakovljevic M., Jalu M.T., Jayatilleke A.U., Jha R.P., Jonas J.B., Jozwiak J.J., Kabir Z., Kadel R., Kahsay A., Kapil U., Kasaeian A., Kassa T.D.D., Katikireddi S.V., Kawakami N., Kebede S., Kefale A.T., Keiyoro P.N., Kengne A.P., Khader Y., Khafaie M.A., Khalil I.A., Khan M.N., Khang Y.-H., Khater M.M., Khubchandani J., Kim C.-I., Kim D., Kim Y.J., Kimokoti R.W., Kisa A., Kivimaki M., Kochhar S., Kosen S., Koul P.A., Koyanagi A., Krishan K., Defo B.K., Bicer B.K., Kulkarni V.S., Kumar P., Lafranconi A., Balaji A.L., Lalloo R., Lallukka T., Lam H., Lami F.H., Lan Q., Lang J.J., Lansky S., Larsson A.O., Latifi A., Leasher J.L., Lee P.H., Leigh J., Leinsalu M., Leung J., Levi M., Li Y., Lim L.-L., Linn S., Liu S., Lobato-Cordero A., Lopez A.D., Lotufo P.A., Macarayan E.R.K., Machado I.E., Madotto F., Abd El Razek H.M., Abd El Razek M.M., Majdan M., Majdzadeh R., Majeed A., Malekzadeh R., Malta D.C., Mapoma C.C., Martinez-Raga J., Maulik P.K., Mazidi M., McKee M., Mehta V., Meier T., Mekonen T., Meles K.G., Melese A., Memiah P.T.N., Mendoza W., Mengistu D.T., Mensah G.A., Meretoja T.J., Mezgebe H.B., Miazgowski T., Miller T.R., Mini G., Mirica A., Mirrakhimov E.M., Moazen B., Mohammad K.A., Mohammadifard N., Mohammed S., Monasta L., Moraga P., Morawska L., Mousavi S.M., Mukhopadhyay S., Musa K.I., Naheed A., Naik G., Najafi F., Nangia V., Nansseu J.R., Nayak M.S.D.P., Nejjari C., Neupane S., Neupane S.P., Ngunjiri J.W., Nguyen C.T., Nguyen L.H., Nguyen T.H., Ningrum D.N.A., Nirayo Y.L., Noubiap J.J., Ofori-Asenso R., Ogbo F.A., Oh I.-H., Oladimeji O., Olagunju A.T., Olivares P.R., Olusanya B.O., Olusanya J.O., Oommen A.M., Oren E., Orpana H.M., Ortega-Altamirano D.D.V., Ortiz J.R., Ota E., Owolabi M.O., Oyekale A.S., Mahesh P.A., Pana A., Park E.-K., Parry C.D.H., Parsian H., Patle A., Patton G.C., Paudel D., Petzold M., Phillips M.R., Pillay J.D., Postma M.J., Pourmalek F., Prabhakaran D., Qorbani M., Radfar A., Rafay A., Rafiei A., Rahim F., Rahimi-Movaghar A., Rahman M., Rahman M.A., Rai R.K., Rajsic S., Raju S.B., Ram U., Rana S.M., Ranabhat C.L., Rawaf D.L., Rawaf S., Reiner R.C., Reis C., Renzaho A.M.N., Rezai M.S., Roever L., Ronfani L., Room R., Roshandel G., Rostami A., Roth G.A., Roy A., Sabde Y.D., Saddik B., Safiri S., Sahebkar A., Saleem Z., Salomon J.A., Salvi S.S., Sanabria J., Sanchez-Nino M.D., Santomauro D.F., Santos I.S., Santric Milicevic M.M.M., Sarker A.R., Sarmiento-Suarez R., Sarrafzadegan N., Sartorius B., Satpathy M., Sawhney M., Saxena S., Saylan M., Schaub M.P., Schmidt M.I., Schneider I.J.C., Schottker B., Schutte A.E., Schwendicke F., Sepanlou S.G., Shaikh M.A., Sharif M., She J., Sheikh A., Shiferaw M.S., Shigematsu M., Shiri R., Shishani K., Shiue I., Shukla S.R., Sigfusdottir I.D., Silva D.A.S., Da Silva N.T., Silveira D.G.A., Sinha D.N., Sitas F., Filho A.M.S., and Soofi M.
Abstract: Background: Alcohol use is a leading risk factor for death and disability, but its overall association with health remains complex given the possible protective effects of moderate alcohol consumption on some conditions. With our comprehensive approach to health accounting within the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we generated improved estimates of alcohol use and alcohol-attributable deaths and disability-adjusted lifeyears (DALYs) for 195 locations from 1990 to 2016, for both sexes and for 5-year age groups between the ages of 15 years and 95 years and older. Method(s): Using 694 data sources of individual and population-level alcohol consumption, along with 592 prospective and retrospective studies on the risk of alcohol use, we produced estimates of the prevalence of current drinking, abstention, the distribution of alcohol consumption among current drinkers in standard drinks daily (defined as 10 g of pure ethyl alcohol), and alcohol-attributable deaths and DALYs. We made several methodological improvements compared with previous estimates: first, we adjusted alcohol sales estimates to take into account tourist and unrecorded consumption; second, we did a new meta-analysis of relative risks for 23 health outcomes associated with alcohol use; and third, we developed a new method to quantify the level of alcohol consumption that minimises the overall risk to individual health. Finding(s): Globally, alcohol use was the seventh leading risk factor for both deaths and DALYs in 2016, accounting for 2.2% (95% uncertainty interval [UI] 1.5-3.0) of age-standardised female deaths and 6.8% (5.8-8.0) of agestandardised male deaths. Among the population aged 15-49 years, alcohol use was the leading risk factor globally in 2016, with 3.8% (95% UI 3.2-4.3) of female deaths and 12.2% (10.8-13.6) of male deaths attributable to alcohol use. For the population aged 15-49 years, female attributable DALYs were 2.3% (95% UI 2.0-2.6) and male attrib
Published: 2018

19. Spending on health and HIV/AIDS: domestic health spending and development assistance in 188 countries, 1995-2015

Author: Dieleman, JL, Haakenstad, A, Micah, A, Moses, M, Abbafati, C, Acharya, P, Adhikari, TB, Adou, AK, Kiadaliri, AA, Alam, K, Alizadeh-Navaei, R, Alkerwi, A, Ammar, W, Antonio, CAT, Aremu, O, Asgedom, SW, Atey, TM, Avila-Burgos, L, Awasthi, A, Ayer, R, Badali, H, Banach, M, Banstola, A, Barac, A, Belachew, AB, Birungi, C, Bragazzi, NL, Breitborde, NJK, Cahuana-Hurtado, L, Car, J, Catala-Lopez, F, Chapin, A, Dandona, L, Dandona, R, Daryani, A, Dharmaratne, SD, Dubey, M, Edessa, D, Eldrenkamp, E, Eshrati, B, Faro, A, Feigl, AB, Fenny, AP, Fischer, F, Foigt, N, Foreman, KJ, Fullman, N, Ghimire, M, Goli, S, Hailu, AD, Hamidi, S, Harb, HL, Hay, SI, Hendrie, D, Ikilezi, G, Javanbakht, M, John, D, Jonas, JB, Kaldjian, A, Kasaeian, A, Kates, J, Khalil, IA, Khang, Y-H, Khubchandani, J, Kim, YJ, Kinge, JM, Kosen, S, Krohn, KJ, Kumar, GA, Lam, H, Listl, S, Abd El Razek, HM, Abd El Razek, MM, Majeed, A, Malekzadeh, R, Malta, DC, Mensah, GA, Meretoja, A, Miller, TR, Mirrakhimov, EM, Mlashu, FW, Mohammed, E, Mohammed, S, Naghavi, M, Nangia, V, Ngalesoni, FN, Cuong, TN, Trang, HN, Niriayo, Y, Noroozi, M, Owolabi, MO, Pereira, DM, Qorbani, M, Rafay, A, Rafiei, A, Rahimi-Movaghar, V, Rai, RK, Ram, U, Ranabhat, CL, Ray, SE, Reiner, RC, Sadat, N, Sajadi, HS, Santos, JV, Sarker, AR, Sartorius, B, Satpathy, M, Savic, M, Schneider, M, Sepanlou, SG, Shaikh, MA, Sharif, M, She, J, Sheikh, A, Sisay, M, Soneji, S, Soofi, M, Tadesse, AH, Tao, T, Templin, T, Tesema, AG, Thapa, S, Thomson, AJ, Tobe-Gai, R, Topor-Madry, R, Bach, XT, Khanh, BT, Tung, TT, Undurraga, EA, Vasankari, T, Violante, FS, Wijeratne, T, Xu, G, Yonemoto, N, Younis, MZ, Yu, C, Zaki, MES, Zhou, L, Zlavog, B, Murray, CJL, Dieleman, JL, Haakenstad, A, Micah, A, Moses, M, Abbafati, C, Acharya, P, Adhikari, TB, Adou, AK, Kiadaliri, AA, Alam, K, Alizadeh-Navaei, R, Alkerwi, A, Ammar, W, Antonio, CAT, Aremu, O, Asgedom, SW, Atey, TM, Avila-Burgos, L, Awasthi, A, Ayer, R, Badali, H, Banach, M, Banstola, A, Barac, A, Belachew, AB, Birungi, C, Bragazzi, NL, Breitborde, NJK, Cahuana-Hurtado, L, Car, J, Catala-Lopez, F, Chapin, A, Dandona, L, Dandona, R, Daryani, A, Dharmaratne, SD, Dubey, M, Edessa, D, Eldrenkamp, E, Eshrati, B, Faro, A, Feigl, AB, Fenny, AP, Fischer, F, Foigt, N, Foreman, KJ, Fullman, N, Ghimire, M, Goli, S, Hailu, AD, Hamidi, S, Harb, HL, Hay, SI, Hendrie, D, Ikilezi, G, Javanbakht, M, John, D, Jonas, JB, Kaldjian, A, Kasaeian, A, Kates, J, Khalil, IA, Khang, Y-H, Khubchandani, J, Kim, YJ, Kinge, JM, Kosen, S, Krohn, KJ, Kumar, GA, Lam, H, Listl, S, Abd El Razek, HM, Abd El Razek, MM, Majeed, A, Malekzadeh, R, Malta, DC, Mensah, GA, Meretoja, A, Miller, TR, Mirrakhimov, EM, Mlashu, FW, Mohammed, E, Mohammed, S, Naghavi, M, Nangia, V, Ngalesoni, FN, Cuong, TN, Trang, HN, Niriayo, Y, Noroozi, M, Owolabi, MO, Pereira, DM, Qorbani, M, Rafay, A, Rafiei, A, Rahimi-Movaghar, V, Rai, RK, Ram, U, Ranabhat, CL, Ray, SE, Reiner, RC, Sadat, N, Sajadi, HS, Santos, JV, Sarker, AR, Sartorius, B, Satpathy, M, Savic, M, Schneider, M, Sepanlou, SG, Shaikh, MA, Sharif, M, She, J, Sheikh, A, Sisay, M, Soneji, S, Soofi, M, Tadesse, AH, Tao, T, Templin, T, Tesema, AG, Thapa, S, Thomson, AJ, Tobe-Gai, R, Topor-Madry, R, Bach, XT, Khanh, BT, Tung, TT, Undurraga, EA, Vasankari, T, Violante, FS, Wijeratne, T, Xu, G, Yonemoto, N, Younis, MZ, Yu, C, Zaki, MES, Zhou, L, Zlavog, B, and Murray, CJL
Abstract: BACKGROUND: Comparable estimates of health spending are crucial for the assessment of health systems and to optimally deploy health resources. The methods used to track health spending continue to evolve, but little is known about the distribution of spending across diseases. We developed improved estimates of health spending by source, including development assistance for health, and, for the first time, estimated HIV/AIDS spending on prevention and treatment and by source of funding, for 188 countries. METHODS: We collected published data on domestic health spending, from 1995 to 2015, from a diverse set of international agencies. We tracked development assistance for health from 1990 to 2017. We also extracted 5385 datapoints about HIV/AIDS spending, between 2000 and 2015, from online databases, country reports, and proposals submitted to multilateral organisations. We used spatiotemporal Gaussian process regression to generate complete and comparable estimates for health and HIV/AIDS spending. We report most estimates in 2017 purchasing-power parity-adjusted dollars and adjust all estimates for the effect of inflation. FINDINGS: Between 1995 and 2015, global health spending per capita grew at an annualised rate of 3·1% (95% uncertainty interval [UI] 3·1 to 3·2), with growth being largest in upper-middle-income countries (5·4% per capita [UI 5·3-5·5]) and lower-middle-income countries (4·2% per capita [4·2-4·3]). In 2015, $9·7 trillion (9·7 trillion to 9·8 trillion) was spent on health worldwide. High-income countries spent $6·5 trillion (6·4 trillion to 6·5 trillion) or 66·3% (66·0 to 66·5) of the total in 2015, whereas low-income countries spent $70·3 billion (69·3 billion to 71·3 billion) or 0·7% (0·7 to 0·7). Between 1990 and 2017, development assistance for health increased by 394·7% ($29·9 billion), with an estimated $37·4 billion of development assistance being disbursed for health in 2017, of which $9·1 billion (24·2%) targeted HIV/AIDS. Between 2000 and
Published: 2018

20. Trends in future health financing and coverage: future health spending and universal health coverage in 188 countries, 2016-40

Author: Dieleman, JL, Sadat, N, Chang, AY, Fullman, N, Abbafati, C, Acharya, P, Adou, AK, Kiadaliri, AA, Alam, K, Alizadeh-Navaei, R, Alkerwi, A, Ammar, W, Antonio, CAT, Arernu, O, Asgedom, SW, Atey, TM, Avila-Burgos, L, Awasthi, A, Ayer, R, Badali, H, Banach, M, Banstola, A, Barac, A, Belachew, AB, Birungi, C, Bragazzi, NL, Breitborde, NJK, Cahuana-Hurtado, L, Car, J, Catala-Lopez, F, Chapin, A, Chen, CS, Dandona, L, Dandona, R, Daryani, A, Dharmaratne, SD, Dubey, M, Edessa, D, Eldrenkamp, E, Eshrati, B, Faro, A, Feigl, AB, Fenny, AP, Fischer, F, Foigt, N, Foreman, KJ, Furst, T, Ghimire, M, Goli, S, Hailu, AD, Hamidi, S, Harb, HL, Hay, SI, Hendrie, D, Ikilezi, G, Javanbakht, M, John, D, Jonas, JB, Kaldjian, A, Kasaeian, A, Kasahun, YC, Khalil, IA, Khang, Y-H, Khubchandani, J, Kim, YJ, Kinge, JM, Kosen, S, Krohn, KJ, Kumar, GA, Lafranconi, A, Lam, H, Listl, S, Abd El Razek, HM, Abd El Razek, MM, Majeed, A, Malekzadeh, R, Malta, DC, Martinez, G, Mensah, GA, Meretoja, A, Micah, A, Miller, TR, Mirrakhimov, EM, Mlashu, FW, Mohammed, E, Mohammed, S, Mokdad, AH, Moses, M, Mousavi, SM, Naghavi, M, Nangia, V, Ngalesoni, FN, Cuong, TN, Trang, HN, Niriayo, Y, Noroozi, M, Owolabi, MO, Patel, T, Pereira, DM, Polinder, S, Qorbani, M, Rafay, A, Rafiei, A, Rahimi-Movaghar, V, Rai, RK, Ram, U, Ranabhat, CL, Ray, SE, Reiner, RC, Sajadi, HS, Santoro, R, Santos, JV, Sarker, AR, Sartorius, B, Satpathy, M, Sepanlou, SG, Shaikh, MA, Sharif, M, She, J, Sheikh, A, Shrime, MG, Sisay, M, Soneji, S, Soofi, M, Sorensen, RJD, Tao, T, Templin, T, Tesema, AG, Thapa, S, Tobe-Gai, R, Topor-Madry, R, Bach, XT, Khanh, BT, Tung, TT, Undurraga, EA, Vasankari, T, Violante, FS, Werdecker, A, Wijeratne, T, Xu, G, Yonemoto, N, Younis, MZ, Yu, C, Zaki, MES, Zlavog, B, Murray, CJL, Dieleman, JL, Sadat, N, Chang, AY, Fullman, N, Abbafati, C, Acharya, P, Adou, AK, Kiadaliri, AA, Alam, K, Alizadeh-Navaei, R, Alkerwi, A, Ammar, W, Antonio, CAT, Arernu, O, Asgedom, SW, Atey, TM, Avila-Burgos, L, Awasthi, A, Ayer, R, Badali, H, Banach, M, Banstola, A, Barac, A, Belachew, AB, Birungi, C, Bragazzi, NL, Breitborde, NJK, Cahuana-Hurtado, L, Car, J, Catala-Lopez, F, Chapin, A, Chen, CS, Dandona, L, Dandona, R, Daryani, A, Dharmaratne, SD, Dubey, M, Edessa, D, Eldrenkamp, E, Eshrati, B, Faro, A, Feigl, AB, Fenny, AP, Fischer, F, Foigt, N, Foreman, KJ, Furst, T, Ghimire, M, Goli, S, Hailu, AD, Hamidi, S, Harb, HL, Hay, SI, Hendrie, D, Ikilezi, G, Javanbakht, M, John, D, Jonas, JB, Kaldjian, A, Kasaeian, A, Kasahun, YC, Khalil, IA, Khang, Y-H, Khubchandani, J, Kim, YJ, Kinge, JM, Kosen, S, Krohn, KJ, Kumar, GA, Lafranconi, A, Lam, H, Listl, S, Abd El Razek, HM, Abd El Razek, MM, Majeed, A, Malekzadeh, R, Malta, DC, Martinez, G, Mensah, GA, Meretoja, A, Micah, A, Miller, TR, Mirrakhimov, EM, Mlashu, FW, Mohammed, E, Mohammed, S, Mokdad, AH, Moses, M, Mousavi, SM, Naghavi, M, Nangia, V, Ngalesoni, FN, Cuong, TN, Trang, HN, Niriayo, Y, Noroozi, M, Owolabi, MO, Patel, T, Pereira, DM, Polinder, S, Qorbani, M, Rafay, A, Rafiei, A, Rahimi-Movaghar, V, Rai, RK, Ram, U, Ranabhat, CL, Ray, SE, Reiner, RC, Sajadi, HS, Santoro, R, Santos, JV, Sarker, AR, Sartorius, B, Satpathy, M, Sepanlou, SG, Shaikh, MA, Sharif, M, She, J, Sheikh, A, Shrime, MG, Sisay, M, Soneji, S, Soofi, M, Sorensen, RJD, Tao, T, Templin, T, Tesema, AG, Thapa, S, Tobe-Gai, R, Topor-Madry, R, Bach, XT, Khanh, BT, Tung, TT, Undurraga, EA, Vasankari, T, Violante, FS, Werdecker, A, Wijeratne, T, Xu, G, Yonemoto, N, Younis, MZ, Yu, C, Zaki, MES, Zlavog, B, and Murray, CJL
Abstract: BACKGROUND: Achieving universal health coverage (UHC) requires health financing systems that provide prepaid pooled resources for key health services without placing undue financial stress on households. Understanding current and future trajectories of health financing is vital for progress towards UHC. We used historical health financing data for 188 countries from 1995 to 2015 to estimate future scenarios of health spending and pooled health spending through to 2040. METHODS: We extracted historical data on gross domestic product (GDP) and health spending for 188 countries from 1995 to 2015, and projected annual GDP, development assistance for health, and government, out-of-pocket, and prepaid private health spending from 2015 through to 2040 as a reference scenario. These estimates were generated using an ensemble of models that varied key demographic and socioeconomic determinants. We generated better and worse alternative future scenarios based on the global distribution of historic health spending growth rates. Last, we used stochastic frontier analysis to investigate the association between pooled health resources and UHC index, a measure of a country's UHC service coverage. Finally, we estimated future UHC performance and the number of people covered under the three future scenarios. FINDINGS: In the reference scenario, global health spending was projected to increase from US$10 trillion (95% uncertainty interval 10 trillion to 10 trillion) in 2015 to $20 trillion (18 trillion to 22 trillion) in 2040. Per capita health spending was projected to increase fastest in upper-middle-income countries, at 4·2% (3·4-5·1) per year, followed by lower-middle-income countries (4·0%, 3·6-4·5) and low-income countries (2·2%, 1·7-2·8). Despite global growth, per capita health spending was projected to range from only $40 (24-65) to $413 (263-668) in 2040 in low-income countries, and from $140 (90-200) to $1699 (711-3423) in lower-middle-income countries. Globally, the share
Published: 2018

21. Stigma reduction in relation to HIV test uptake in low- and middle-income countries: a realist review

Author: Thapa, S, Hannes, K, Cargo, M, Buve, A, Peters, S, Dauphin, S, Mathei, C, Thapa, S, Hannes, K, Cargo, M, Buve, A, Peters, S, Dauphin, S, and Mathei, C
Abstract: BACKGROUND: This realist review was conducted to understand how stigma is reduced in relation to HIV test uptake in low- and middle-income countries (LMICs). METHODS: A systematic search of eight databases resulted in 34 articles considered for synthesis. Data synthesis was guided by a preliminary programme theory and included coding the meaning units to develop themes or intervention pathways that corresponded to context-mechanism-outcome configurations. RESULTS: We found that the interventions produced an effect through two pathways: (a) knowledge leads to changes in stigmatizing attitudes and increases in HIV test uptake and (b) knowledge and attitudes lead to changes in stigmatizing behaviours and lead to HIV test uptake. We also found one competing pathway that illustrated the direct impact of knowledge on HIV test uptake without changing stigmatizing attitudes and behaviour. The identified pathways were found to be influenced by some structural factors (e.g., anti-homosexuality laws, country-specific HIV testing programmes and policies), community factors (e.g., traditional beliefs and practices, sexual taboos and prevalence of intimate partner violence) and target-population characteristics (e.g., age, income and urban-rural residence). CONCLUSIONS: The pathways and underlying mechanisms support the adaptation of intervention strategies in terms of social context and the target population in LMICs.
Published: 2018

22. Quantifying primaquine effectiveness and improving adherence: a round table discussion of the APMEN Vivax Working Group

Author: Thriemer, K, Bobogare, A, Ley, B, Gudo, CS, Alam, MS, Anstey, NM, Ashley, E, Baird, JK, Gryseels, C, Jambert, E, Lacerda, M, Laihad, F, Marfurt, J, Pasaribu, AP, Poespoprodjo, JR, Sutanto, I, Taylor, WR, van den Boogaard, C, Battle, KE, Dysoley, L, Ghimire, P, Hawley, B, Hwang, J, Khan, WA, Mudin, RNB, Sumiwi, ME, Ahmed, R, Aktaruzzaman, MM, Awasthi, KR, Bardaji, A, Bell, D, Boaz, L, Burdam, FH, Chandramohan, D, Cheng, Q, Chindawongsa, K, Culpepper, J, Das, S, Deray, R, Desai, M, Domingo, G, Wang, D, Duparc, S, Floranita, R, Gerth-Guyette, E, Howes, RE, Hugo, C, Jagoe, G, Sariwati, E, Jhora, ST, Wu, J, Karunajeewa, H, Kenangalem, E, Lal, BK, Landuwulang, C, Le Perru, E, Lee, S-E, Makita, LS, McCarthy, J, Mekuria, A, Mishra, N, Naket, E, Nambanya, S, Nausien, J, Thang, ND, Thuan, NT, Noviyanti, R, Pfeffer, D, Qi, G, Rahmalia, A, Rogerson, S, Samad, I, Sattabongkot, J, Satyagraha, A, Shanks, D, Sharma, SN, Sibley, CH, Sungkar, A, Syafruddin, D, Talukdar, A, Tarning, J, ter Kuile, F, Thapa, S, Theodora, M, Tho, TH, Waramin, E, Waramori, G, Woyessa, A, Wongsrichanalai, C, Xa, NX, Yeom, JS, Hermawan, L, Devine, A, Nowak, S, Jaya, I, Supargiyono, S, Grietens, KP, Price, RN, Thriemer, K, Bobogare, A, Ley, B, Gudo, CS, Alam, MS, Anstey, NM, Ashley, E, Baird, JK, Gryseels, C, Jambert, E, Lacerda, M, Laihad, F, Marfurt, J, Pasaribu, AP, Poespoprodjo, JR, Sutanto, I, Taylor, WR, van den Boogaard, C, Battle, KE, Dysoley, L, Ghimire, P, Hawley, B, Hwang, J, Khan, WA, Mudin, RNB, Sumiwi, ME, Ahmed, R, Aktaruzzaman, MM, Awasthi, KR, Bardaji, A, Bell, D, Boaz, L, Burdam, FH, Chandramohan, D, Cheng, Q, Chindawongsa, K, Culpepper, J, Das, S, Deray, R, Desai, M, Domingo, G, Wang, D, Duparc, S, Floranita, R, Gerth-Guyette, E, Howes, RE, Hugo, C, Jagoe, G, Sariwati, E, Jhora, ST, Wu, J, Karunajeewa, H, Kenangalem, E, Lal, BK, Landuwulang, C, Le Perru, E, Lee, S-E, Makita, LS, McCarthy, J, Mekuria, A, Mishra, N, Naket, E, Nambanya, S, Nausien, J, Thang, ND, Thuan, NT, Noviyanti, R, Pfeffer, D, Qi, G, Rahmalia, A, Rogerson, S, Samad, I, Sattabongkot, J, Satyagraha, A, Shanks, D, Sharma, SN, Sibley, CH, Sungkar, A, Syafruddin, D, Talukdar, A, Tarning, J, ter Kuile, F, Thapa, S, Theodora, M, Tho, TH, Waramin, E, Waramori, G, Woyessa, A, Wongsrichanalai, C, Xa, NX, Yeom, JS, Hermawan, L, Devine, A, Nowak, S, Jaya, I, Supargiyono, S, Grietens, KP, and Price, RN
Abstract: The goal to eliminate malaria from the Asia-Pacific by 2030 will require the safe and widespread delivery of effective radical cure of malaria. In October 2017, the Asia Pacific Malaria Elimination Network Vivax Working Group met to discuss the impediments to primaquine (PQ) radical cure, how these can be overcome and the methodological difficulties in assessing clinical effectiveness of radical cure. The salient discussions of this meeting which involved 110 representatives from 18 partner countries and 21 institutional partner organizations are reported. Context specific strategies to improve adherence are needed to increase understanding and awareness of PQ within affected communities; these must include education and health promotion programs. Lessons learned from other disease programs highlight that a package of approaches has the greatest potential to change patient and prescriber habits, however optimizing the components of this approach and quantifying their effectiveness is challenging. In a trial setting, the reactivity of participants results in patients altering their behaviour and creates inherent bias. Although bias can be reduced by integrating data collection into the routine health care and surveillance systems, this comes at a cost of decreasing the detection of clinical outcomes. Measuring adherence and the factors that relate to it, also requires an in-depth understanding of the context and the underlying sociocultural logic that supports it. Reaching the elimination goal will require innovative approaches to improve radical cure for vivax malaria, as well as the methods to evaluate its effectiveness.
Published: 2018

23. Observation of Negative Magnetic Hysteresis Loop in ZnO Thin Films

Author: Haseman, M., Winarksi, D., Saadatkia, P., Hernandez, A., Kusz, M., Anwand, W., Wagner, A., Thapa, S., Colosimo, A. M., Selim, F. A., Haseman, M., Winarksi, D., Saadatkia, P., Hernandez, A., Kusz, M., Anwand, W., Wagner, A., Thapa, S., Colosimo, A. M., and Selim, F. A.
Abstract: We report on the observation of an unusual negative magnetic hysteresis loop in ZnO thin film co-doped with cobalt and aluminum (Co-Al:ZnO), while other transition-metal doped ZnO films such as Cu-doped ZnO and Mn-doped ZnO, exhibit normal hysteresis loops. The unusual magnetic behavior is ascribed to the presence of double magnetic layers with different magnetic moments due to the change of structural defects across the film layers. Positron annihilation measurements confirmed the presence of unique microstructural changes in the Co-Al:ZnO film. This study shows that defects in diluted magnetic semiconductors may induce not only ferromagnetism but also novel magnetic behaviors.
Published: 2018

24. Alcohol use and burden for 195 countries and territories, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016

Author: Griswold, M, Fullman, N, Hawley, C, Arian, N, Zimsen, S, Tymeson, H, Venkateswaran, V, Tapp, A, Forouzanfar, M, Salama, J, Abate, K, Abate, D, Abay, S, Abbafati, C, Abdulkader, R, Abebe, Z, Aboyans, V, Abrar, M, Acharya, P, Adetokunboh, O, Adhikari, T, Adsuar, J, Afarideh, M, Agardh, E, Agarwal, G, Aghayan, S, Agrawal, S, Ahmed, M, Akibu, M, Akinyemiju, T, Akseer, N, Asfoor, D, Al-Aly, Z, Alahdab, F, Alam, K, Albujeer, A, Alene, K, Ali, R, Ali, S, Alijanzadeh, M, Aljunid, S, Alkerwi, A, Allebeck, P, Alvis-Guzman, N, Amare, A, Aminde, L, Ammar, W, Amoako, Y, Amul, G, Andrei, C, Angus, C, Ansha, M, Antonio, C, Aremu, O, Ärnlöv, J, Artaman, A, Aryal, K, Assadi, R, Ausloos, M, Avila-Burgos, L, Avokpaho, E, Awasthi, A, Ayele, H, Ayer, R, Ayuk, T, Azzopardi, P, Badali, H, Badawi, A, Banach, M, Barker-Collo, S, Barrero, L, Basaleem, H, Baye, E, Bazargan-Hejazi, S, Bedi, N, Béjot, Y, Belachew, A, Belay, S, Bennett, D, Bensenor, I, Bernabe, E, Bernstein, R, Beyene, A, Beyranvand, T, Bhaumik, S, Bhutta, Z, Biadgo, B, Bijani, A, Bililign, N, Birlik, S, Birungi, C, Bizuneh, H, Bjerregaard, P, Bjørge, T, Borges, G, Bosetti, C, Boufous, S, Bragazzi, N, Brenner, H, Butt, Z, Cahuana-Hurtado, L, Calabria, B, Campos-Nonato, I, Campuzano, J, Carreras, G, Carrero, J, Carvalho, F, Castañeda-Orjuela, C, Castillo Rivas, J, Catalá-López, F, Chang, J, Charlson, F, Chattopadhyay, A, Chaturvedi, P, Chowdhury, R, Christopher, D, Chung, S, Ciobanu, L, Claro, R, Conti, S, Cousin, E, Criqui, M, Dachew, B, Dargan, P, Daryani, A, Das Neves, J, Davletov, K, De Castro, F, De Courten, B, De Neve, J, Degenhardt, L, Demoz, G, Des Jarlais, D, Dey, S, Dhaliwal, R, Dharmaratne, S, Dhimal, M, Doku, D, Doyle, K, Dubey, M, Dubljanin, E, Duncan, B, Ebrahimi, H, Edessa, D, El Sayed Zaki, M, Ermakov, S, Erskine, H, Esteghamati, A, Faramarzi, M, Farioli, A, Faro, A, Farvid, M, Farzadfar, F, Feigin, V, Felisbino-Mendes, M, Fernandes, E, Ferrari, A, Ferri, C, Fijabi, D, Filip, I, Finger, J, Fischer, F, Flaxman, A, Franklin, R, Futran, N, Gallus, S, Ganji, M, Gankpe, F, Gebregergs, G, Gebrehiwot, T, Geleijnse, J, Ghadimi, R, Ghandour, L, Ghimire, M, Gill, P, Ginawi, I, Giref, A, Gona, P, Gopalani, S, Gotay, C, Goulart, A, Greaves, F, Grosso, G, Guo, Y, Gupta, R, Gupta, V, Gutiérrez, R, Gvs, M, Hafezi-Nejad, N, Hagos, T, Hailu, G, Hamadeh, R, Hamidi, S, Hankey, G, Harb, H, Harikrishnan, S, Haro, J, Hassen, H, Havmoeller, R, Hay, S, Heibati, B, Henok, A, Heredia-Pi, I, Hernández-Llanes, N, Herteliu, C, Hibstu, D, Hoogar, P, Horita, N, Hosgood, H, Hosseini, M, Hostiuc, M, Hu, G, Huang, H, Husseini, A, Idrisov, B, Ileanu, B, Ilesanmi, O, Irvani, S, Islam, S, Jackson, M, Jakovljevic, M, Jalu, M, Jayatilleke, A, Jha, R, Jonas, J, Jozwiak, J, Kabir, Z, Kadel, R, Kahsay, A, Kapil, U, Kasaeian, A, Kassa, T, Katikireddi, S, Kawakami, N, Kebede, S, Kefale, A, Keiyoro, P, Kengne, A, Khader, Y, Khafaie, M, Khalil, I, Khan, M, Khang, Y, Khater, M, Khubchandani, J, Kim, C, Kim, D, Kim, Y, Kimokoti, R, Kisa, A, Kivimäki, M, Kochhar, S, Kosen, S, Koul, P, Koyanagi, A, Krishan, K, Kuate Defo, B, Kucuk Bicer, B, Kulkarni, V, Kumar, P, Lafranconi, A, Lakshmana Balaji, A, Lalloo, R, Lallukka, T, Lam, H, Lami, F, Lan, Q, Lang, J, Lansky, S, Larsson, A, Latifi, A, Leasher, J, Lee, P, Leigh, J, Leinsalu, M, Leung, J, Levi, M, Li, Y, Lim, L, Linn, S, Liu, S, Lobato-Cordero, A, Lopez, A, Lotufo, P, Macarayan, E, Machado, I, Madotto, F, Magdy Abd El Razek, H, Magdy Abd El Razek, M, Majdan, M, Majdzadeh, R, Majeed, A, Malekzadeh, R, Malta, D, Mapoma, C, Martinez-Raga, J, Maulik, P, Mazidi, M, Mckee, M, Mehta, V, Meier, T, Mekonen, T, Meles, K, Melese, A, Memiah, P, Mendoza, W, Mengistu, D, Mensah, G, Meretoja, T, Mezgebe, H, Miazgowski, T, Miller, T, Mini, G, Mirica, A, Mirrakhimov, E, Moazen, B, Mohammad, K, Mohammadifard, N, Mohammed, S, Monasta, L, Moraga, P, Morawska, L, Mousavi, S, Mukhopadhyay, S, Musa, K, Naheed, A, Naik, G, Najafi, F, Nangia, V, Nansseu, J, Nayak, M, Nejjari, C, Neupane, S, Ngunjiri, J, Nguyen, C, Nguyen, L, Nguyen, T, Ningrum, D, Nirayo, Y, Noubiap, J, Ofori-Asenso, R, Ogbo, F, Oh, I, Oladimeji, O, Olagunju, A, Olivares, P, Olusanya, B, Olusanya, J, Oommen, A, Oren, E, Orpana, H, Ortega-Altamirano, D, Ortiz, J, Ota, E, Owolabi, M, Oyekale, A, P A, M, Pana, A, Park, E, Parry, C, Parsian, H, Patle, A, Patton, G, Paudel, D, Petzold, M, Phillips, M, Pillay, J, Postma, M, Pourmalek, F, Prabhakaran, D, Qorbani, M, Radfar, A, Rafay, A, Rafiei, A, Rahim, F, Rahimi-Movaghar, A, Rahman, M, Rai, R, Rajsic, S, Raju, S, Ram, U, Rana, S, Ranabhat, C, Rawaf, D, Rawaf, S, Reiner, R, Reis, C, Renzaho, A, Rezai, M, Roever, L, Ronfani, L, Room, R, Roshandel, G, Rostami, A, Roth, G, Roy, A, Sabde, Y, Saddik, B, Safiri, S, Sahebkar, A, Saleem, Z, Salomon, J, Salvi, S, Sanabria, J, Sanchez-Niño, M, Santomauro, D, Santos, I, Santric Milicevic, M, Sarker, A, Sarmiento-Suárez, R, Sarrafzadegan, N, Sartorius, B, Satpathy, M, Sawhney, M, Saxena, S, Saylan, M, Schaub, M, Schmidt, M, Schneider, I, Schöttker, B, Schutte, A, Schwendicke, F, Sepanlou, S, Shaikh, M, Sharif, M, She, J, Sheikh, A, Shen, J, Shiferaw, M, Shigematsu, M, Shiri, R, Shishani, K, Shiue, I, Shukla, S, Sigfusdottir, I, Silva, D, Silva, N, Silveira, D, Sinha, D, Sitas, F, Soares Filho, A, Soofi, M, Sorensen, R, Soriano, J, Sreeramareddy, C, Steckling, N, Stein, D, Sufiyan, M, Sur, P, Sykes, B, Tabarés-Seisdedos, R, Tabuchi, T, Tavakkoli, M, Tehrani-Banihashemi, A, Tekle, M, Thapa, S, Thomas, N, Topor-Madry, R, Topouzis, F, Tran, B, Troeger, C, Truelsen, T, Tsilimparis, N, Tyrovolas, S, Ukwaja, K, Ullah, I, Uthman, O, Valdez, P, Van Boven, J, Vasankari, T, Venketasubramanian, N, Violante, F, Vladimirov, S, Vlassov, V, Vollset, S, Vos, T, Wagnew, F, Waheed, Y, Wang, Y, Weiderpass, E, Weldegebreal, F, Weldegwergs, K, Werdecker, A, Westerman, R, Whiteford, H, Widecka, J, Wijeratne, T, Wyper, G, Xu, G, Yamada, T, Yano, Y, Ye, P, Yimer, E, Yip, P, Yirsaw, B, Yisma, E, Yonemoto, N, Yoon, S, Yotebieng, M, Younis, M, Zachariah, G, Zaidi, Z, Zamani, M, Zhang, X, Zodpey, S, Mokdad, A, Naghavi, M, Murray, C, Gakidou, E, Griswold, Max G, Fullman, Nancy, Hawley, Caitlin, Arian, Nicholas, Zimsen, Stephanie R M, Tymeson, Hayley D, Venkateswaran, Vidhya, Tapp, Austin Douglas, Forouzanfar, Mohammad H, Salama, Joseph S, Abate, Kalkidan Hassen, Abate, Degu, Abay, Solomon M, Abbafati, Cristiana, Abdulkader, Rizwan Suliankatchi, Abebe, Zegeye, Aboyans, Victor, Abrar, Mohammed Mehdi, Acharya, Pawan, Adetokunboh, Olatunji O, Adhikari, Tara Ballav, Adsuar, Jose C, Afarideh, Mohsen, Agardh, Emilie Elisabet, Agarwal, Gina, Aghayan, Sargis Aghasi, Agrawal, Sutapa, Ahmed, Muktar Beshir, Akibu, Mohammed, Akinyemiju, Tomi, Akseer, Nadia, Asfoor, Deena H Al, Al-Aly, Ziyad, Alahdab, Fares, Alam, Khurshid, Albujeer, Ammar, Alene, Kefyalew Addis, Ali, Raghib, Ali, Syed Danish, Alijanzadeh, Mehran, Aljunid, Syed Mohamed, Alkerwi, Ala'a, Allebeck, Peter, Alvis-Guzman, Nelson, Amare, Azmeraw T, Aminde, Leopold N, Ammar, Walid, Amoako, Yaw Ampem, Amul, Gianna Gayle Herrera, Andrei, Catalina Liliana, Angus, Colin, Ansha, Mustafa Geleto, Antonio, Carl Abelardo T, Aremu, Olatunde, Ärnlöv, Johan, Artaman, Al, Aryal, Krishna K, Assadi, Reza, Ausloos, Marcel, Avila-Burgos, Leticia, Avokpaho, Euripide F, Awasthi, Ashish, Ayele, Henok Tadesse, Ayer, Rakesh, Ayuk, Tambe B, Azzopardi, Peter S, Badali, Hamid, Badawi, Alaa, Banach, Maciej, Barker-Collo, Suzanne Lyn, Barrero, Lope H, Basaleem, Huda, Baye, Estifanos, Bazargan-Hejazi, Shahrzad, Bedi, Neeraj, Béjot, Yannick, Belachew, Abate Bekele, Belay, Saba Abraham, Bennett, Derrick A, Bensenor, Isabela M, Bernabe, Eduardo, Bernstein, Robert S, Beyene, Addisu Shunu, Beyranvand, Tina, Bhaumik, Soumyadeeep, Bhutta, Zulfiqar A, Biadgo, Belete, Bijani, Ali, Bililign, Nigus, Birlik, Sait Mentes, Birungi, Charles, Bizuneh, Hailemichael, Bjerregaard, Peter, Bjørge, Tone, Borges, Guilherme, Bosetti, Cristina, Boufous, 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Albujeer, Ammar, Alene, Kefyalew Addis, Ali, Raghib, Ali, Syed Danish, Alijanzadeh, Mehran, Aljunid, Syed Mohamed, Alkerwi, Ala'a, Allebeck, Peter, Alvis-Guzman, Nelson, Amare, Azmeraw T, Aminde, Leopold N, Ammar, Walid, Amoako, Yaw Ampem, Amul, Gianna Gayle Herrera, Andrei, Catalina Liliana, Angus, Colin, Ansha, Mustafa Geleto, Antonio, Carl Abelardo T, Aremu, Olatunde, Ärnlöv, Johan, Artaman, Al, Aryal, Krishna K, Assadi, Reza, Ausloos, Marcel, Avila-Burgos, Leticia, Avokpaho, Euripide F, Awasthi, Ashish, Ayele, Henok Tadesse, Ayer, Rakesh, Ayuk, Tambe B, Azzopardi, Peter S, Badali, Hamid, Badawi, Alaa, Banach, Maciej, Barker-Collo, Suzanne Lyn, Barrero, Lope H, Basaleem, Huda, Baye, Estifanos, Bazargan-Hejazi, Shahrzad, Bedi, Neeraj, Béjot, Yannick, Belachew, Abate Bekele, Belay, Saba Abraham, Bennett, Derrick A, Bensenor, Isabela M, Bernabe, Eduardo, Bernstein, Robert S, Beyene, Addisu Shunu, Beyranvand, Tina, Bhaumik, Soumyadeeep, Bhutta, Zulfiqar A, Biadgo, Belete, Bijani, Ali, Bililign, Nigus, Birlik, Sait Mentes, Birungi, Charles, Bizuneh, Hailemichael, Bjerregaard, Peter, Bjørge, Tone, Borges, Guilherme, Bosetti, Cristina, Boufous, Soufiane, Bragazzi, Nicola Luigi, Brenner, Hermann, Butt, Zahid A, Cahuana-Hurtado, Lucero, Calabria, Bianca, Campos-Nonato, Ismael R, Campuzano, Julio Cesar, Carreras, Giulia, Carrero, Juan J, Carvalho, Félix, Castañeda-Orjuela, Carlos A, Castillo Rivas, Jacqueline, Catalá-López, Ferrán, Chang, Jung-Chen, Charlson, Fiona J, Chattopadhyay, Aparajita, Chaturvedi, Pankaj, Chowdhury, Rajiv, Christopher, Devasahayam J, Chung, Sheng-Chia, Ciobanu, Liliana G, Claro, Rafael M, Conti, Sara, Cousin, Ewerton, Criqui, Michael H, Dachew, Berihun Assefa, Dargan, Paul I, Daryani, Ahmad, Das Neves, José, Davletov, Kairat, De Castro, Filipa, De Courten, Barbora, De Neve, Jan-Walter, Degenhardt, Louisa, Demoz, Gebre Teklemariam, Des Jarlais, Don C, Dey, Subhojit, Dhaliwal, Rupinder Singh, Dharmaratne, Samath Dhamminda, Dhimal, Meghnath, Doku, David Teye, Doyle, Kerrie E, Dubey, Manisha, Dubljanin, Eleonora, Duncan, Bruce B, Ebrahimi, Hedyeh, Edessa, Dumessa, El Sayed Zaki, Maysaa, Ermakov, Sergei Petrovich, Erskine, Holly E, Esteghamati, Alireza, Faramarzi, Mahbobeh, Farioli, Andrea, Faro, Andre, Farvid, Maryam S, Farzadfar, Farshad, Feigin, Valery L, Felisbino-Mendes, Mariana Santos, Fernandes, Eduarda, Ferrari, Alize J, Ferri, Cleusa P, Fijabi, Daniel Obadare, Filip, Irina, Finger, Jonas David, Fischer, Florian, Flaxman, Abraham D, Franklin, Richard Charles, Futran, Neal D, Gallus, Silvano, Ganji, Morsaleh, Gankpe, Fortune Gbetoho, Gebregergs, Gebremedhin Berhe, Gebrehiwot, Tsegaye Tewelde, Geleijnse, Johanna M, Ghadimi, Reza, Ghandour, Lilian A, Ghimire, Mamata, Gill, Paramjit Singh, Ginawi, Ibrahim Abdelmageed, Giref, Ababi Zergaw Z, Gona, Philimon N, Gopalani, Sameer Vali, Gotay, Carolyn C, Goulart, Alessandra C, Greaves, Felix, Grosso, Giuseppe, Guo, Yuming, Gupta, Rahul, Gupta, Rajeev, Gupta, Vipin, Gutiérrez, Reyna Alma, GVS, Murthy, Hafezi-Nejad, Nima, Hagos, Tekleberhan Beyene, Hailu, Gessessew Bugssa, Hamadeh, Randah R, Hamidi, Samer, Hankey, Graeme J, Harb, Hilda L, Harikrishnan, Sivadasanpillai, Haro, Josep Maria, Hassen, Hamid Yimam, Havmoeller, Rasmus, Hay, Simon I, Heibati, Behzad, Henok, Andualem, Heredia-Pi, Ileana, Hernández-Llanes, Norberto Francisco, Herteliu, Claudiu, Hibstu, Desalegn Ts Tsegaw, Hoogar, Praveen, Horita, Nobuyuki, Hosgood, H Dean, Hosseini, Mostafa, Hostiuc, Mihaela, Hu, Guoqing, Huang, Hsiang, Husseini, Abdullatif, Idrisov, Bulat, Ileanu, Bogdan Vasile, Ilesanmi, Olayinka Stephen, Irvani, Seyed Sina Naghibi, Islam, Sheikh Mohammed Shariful, Jackson, Maria D, Jakovljevic, Mihajlo, Jalu, Moti Tolera, Jayatilleke, Achala Upendra, Jha, Ravi Prakash, Jonas, Jost B, Jozwiak, Jacek Jerzy, Kabir, Zubair, Kadel, Rajendra, Kahsay, Amaha, Kapil, Umesh, Kasaeian, Amir, Kassa, Tesfaye D Dessale, Katikireddi, Srinivasa Vittal, Kawakami, Norito, Kebede, Seifu, Kefale, Adane Teshome, Keiyoro, Peter Njenga, Kengne, Andre Pascal, Khader, Yousef, Khafaie, Morteza Abdullatif, Khalil, Ibrahim A, Khan, Md Nuruzzaman, Khang, Young-Ho, Khater, Mona M, Khubchandani, Jagdish, Kim, Cho-Il, Kim, Daniel, Kim, Yun Jin, Kimokoti, Ruth W, Kisa, Adnan, Kivimäki, Mika, Kochhar, Sonali, Kosen, Soewarta, Koul, Parvaiz A, Koyanagi, Ai, Krishan, Kewal, Kuate Defo, Barthelemy, Kucuk Bicer, Burcu, Kulkarni, Veena S, Kumar, Pushpendra, Lafranconi, Alessandra, Lakshmana Balaji, Arjun, Lalloo, Ratilal, Lallukka, Tea, Lam, Hilton, Lami, Faris Hasan, Lan, Qing, Lang, Justin J, Lansky, Sonia, Larsson, Anders O, Latifi, Arman, Leasher, Janet L, Lee, Paul H, Leigh, James, Leinsalu, Mall, Leung, Janni, Levi, Miriam, Li, Yichong, Lim, Lee-Ling, Linn, Shai, Liu, Shiwei, Lobato-Cordero, Andrea, Lopez, Alan D, Lotufo, Paulo A, Macarayan, Erlyn Rachelle King, Machado, Isis Eloah, Madotto, Fabiana, Magdy Abd El Razek, Hassan, Magdy Abd El Razek, Muhammed, Majdan, Marek, Majdzadeh, Reza, Majeed, Azeem, Malekzadeh, Reza, Malta, Deborah Carvalho, Mapoma, Chabila Christopher, Martinez-Raga, Jose, Maulik, Pallab K, Mazidi, Mohsen, Mckee, Martin, Mehta, Varshil, Meier, Toni, Mekonen, Tesfa, Meles, Kidanu Gebremariam, Melese, Addisu, Memiah, Peter T N, Mendoza, Walter, Mengistu, Desalegn Tadese, Mensah, George A, Meretoja, Tuomo J, Mezgebe, Haftay Berhane, Miazgowski, Tomasz, Miller, Ted R, Mini, Gk, Mirica, Andreea, Mirrakhimov, Erkin M, Moazen, Babak, Mohammad, Karzan Abdulmuhsin, Mohammadifard, Noushin, Mohammed, Shafiu, Monasta, Lorenzo, Moraga, Paula, Morawska, Lidia, Mousavi, Seyyed Meysam, Mukhopadhyay, Satinath, Musa, Kamarul Imran, Naheed, Aliya, Naik, Gurudatta, Najafi, Farid, Nangia, Vinay, Nansseu, Jobert Richie, Nayak, Mudavath Siva Durga Prasad, Nejjari, Chakib, Neupane, Subas, Neupane, Sudan Prasad, Ngunjiri, Josephine W, Nguyen, Cuong Tat, Nguyen, Long Hoang, Nguyen, Trang Huyen, Ningrum, Dina Nur Anggraini, Nirayo, Yirga Legesse, Noubiap, Jean Jacques, Ofori-Asenso, Richard, Ogbo, Felix Akpojene, Oh, In-Hwan, Oladimeji, Olanrewaju, Olagunju, Andrew T, Olivares, Pedro R, Olusanya, Bolajoko Olubukunola, Olusanya, Jacob Olusegun, Oommen, Anu Mary, Oren, Eyal, Orpana, Heather M, Ortega-Altamirano, Doris D V, Ortiz, Justin R, Ota, Erika, Owolabi, Mayowa Ojo, Oyekale, Abayomi Samuel, P A, Mahesh, Pana, Adrian, Park, Eun-Kee, Parry, Charles D H, Parsian, Hadi, Patle, Ajay, Patton, George C, Paudel, Deepak, Petzold, Max, Phillips, Michael R, Pillay, Julian David, Postma, Maarten J, Pourmalek, Farshad, Prabhakaran, Dorairaj, Qorbani, Mostafa, Radfar, Amir, Rafay, Anwar, Rafiei, Alireza, Rahim, Fakher, Rahimi-Movaghar, Afarin, Rahman, Mahfuzar, Rahman, Muhammad Aziz, Rai, Rajesh Kumar, Rajsic, Sasa, Raju, Sree Bhushan, Ram, Usha, Rana, Saleem M, Ranabhat, Chhabi Lal, Rawaf, David Laith, Rawaf, Salman, Reiner, Robert C, Reis, Cesar, Renzaho, Andre M N, Rezai, Mohammad Sadegh, Roever, Leonardo, Ronfani, Luca, Room, Robin, Roshandel, Gholamreza, Rostami, Ali, Roth, Gregory A, Roy, Ambuj, Sabde, Yogesh Damodar, Saddik, Basema, Safiri, Saeid, Sahebkar, Amirhossein, Saleem, Zikria, Salomon, Joshua A, Salvi, Sundeep Santosh, Sanabria, Juan, Sanchez-Niño, Maria Dolores, Santomauro, Damian Francesco, Santos, Itamar S, Santric Milicevic, Milena M M, Sarker, Abdur Razzaque, Sarmiento-Suárez, Rodrigo, Sarrafzadegan, Nizal, Sartorius, Benn, Satpathy, Maheswar, Sawhney, Monika, Saxena, Sonia, Saylan, Mete, Schaub, Michael P, Schmidt, Maria Inês, Schneider, Ione J C, Schöttker, Ben, Schutte, Aletta Elisabeth, Schwendicke, Falk, Sepanlou, Sadaf G, Shaikh, Masood Ali, Sharif, Mehdi, She, Jun, Sheikh, Aziz, Shen, Jiabin, Shiferaw, Mekonnen Sisay, Shigematsu, Mika, Shiri, Rahman, Shishani, Kawkab, Shiue, Ivy, Shukla, Sharvari Rahul, Sigfusdottir, Inga Dora, Silva, Diego Augusto Santos, Silva, Natacha Torres Da, Silveira, Dayane Gabriele Alves, Sinha, Dhirendra Narain, Sitas, Freddy, Soares Filho, Adauto Martins, Soofi, Moslem, Sorensen, Reed J D, Soriano, Joan B, Sreeramareddy, Chandrashekhar T, Steckling, Nadine, Stein, Dan J, Sufiyan, Mu'awiyyah Babale, Sur, Patrick J, Sykes, Bryan L, Tabarés-Seisdedos, Rafael, Tabuchi, Takahiro, Tavakkoli, Mohammad, Tehrani-Banihashemi, Arash, Tekle, Merhawi Gebremedhin, Thapa, Subash, Thomas, Nihal, Topor-Madry, Roman, Topouzis, Fotis, Tran, Bach Xuan, Troeger, Christopher E, Truelsen, Thomas Clement, Tsilimparis, Nikolaos, Tyrovolas, Stefanos, Ukwaja, Kingsley Nnanna, Ullah, Irfan, Uthman, Olalekan A, Valdez, Pascual R, Van Boven, Job F M, Vasankari, Tommi Juhani, Venketasubramanian, Narayanaswamy, Violante, Francesco S, Vladimirov, Sergey Konstantinovitch, Vlassov, Vasily, Vollset, Stein Emil, Vos, Theo, Wagnew, Fasil Wagnew Shiferaw, Waheed, Yasir, Wang, Yuan-Pang, Weiderpass, Elisabete, Weldegebreal, Fitsum, Weldegwergs, Kidu Gidey, Werdecker, Andrea, Westerman, Ronny, Whiteford, Harvey A, Widecka, Justyna, Wijeratne, Tissa, Wyper, Grant M A, Xu, Gelin, Yamada, Tomohide, Yano, Yuichiro, Ye, Pengpeng, Yimer, Ebrahim M, Yip, Paul, Yirsaw, Biruck Desalegn, Yisma, Engida, Yonemoto, Naohiro, Yoon, Seok-Jun, Yotebieng, Marcel, Younis, Mustafa Z, Zachariah, Geevar, Zaidi, Zoubida, Zamani, Mohammad, Zhang, Xueying, Zodpey, Sanjay, Mokdad, Ali H, Naghavi, Mohsen, Murray, Christopher J L, and Gakidou, Emmanuela
Abstract: Background: Alcohol use is a leading risk factor for death and disability, but its overall association with health remains complex given the possible protective effects of moderate alcohol consumption on some conditions. With our comprehensive approach to health accounting within the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we generated improved estimates of alcohol use and alcohol-attributable deaths and disability-adjusted lifeyears (DALYs) for 195 locations from 1990 to 2016, for both sexes and for 5-year age groups between the ages of 15 years and 95 years and older. Methods: Using 694 data sources of individual and population-level alcohol consumption, along with 592 prospective and retrospective studies on the risk of alcohol use, we produced estimates of the prevalence of current drinking, abstention, the distribution of alcohol consumption among current drinkers in standard drinks daily (defined as 10 g of pure ethyl alcohol), and alcohol-attributable deaths and DALYs. We made several methodological improvements compared with previous estimates: first, we adjusted alcohol sales estimates to take into account tourist and unrecorded consumption; second, we did a new meta-analysis of relative risks for 23 health outcomes associated with alcohol use; and third, we developed a new method to quantify the level of alcohol consumption that minimises the overall risk to individual health. Findings: Globally, alcohol use was the seventh leading risk factor for both deaths and DALYs in 2016, accounting for 2·2% (95% uncertainty interval [UI] 1·5-3·0) of age-standardised female deaths and 6·8% (5·8-8·0) of agestandardised male deaths. Among the population aged 15-49 years, alcohol use was the leading risk factor globally in 2016, with 3·8% (95% UI 3·2-4·3) of female deaths and 12·2% (10·8-13·6) of male deaths attributable to alcohol use. For the population aged 15-49 years, female attributable DALYs were 2·3% (95% UI 2·0-2·6) and male attributab
Published: 2018

25. Assessment of primary labeling of medicines manufactured by Nepalese pharmaceutical industries.

Author: Poudel, RS, Shrestha, S, Thapa, S, Poudel, BK, Chhetri, M, Poudel, RS, Shrestha, S, Thapa, S, Poudel, BK, and Chhetri, M
Abstract: Background: Appropriate labeling of marketed medicines is necessary to fulfill the regulatory provisions and ensure patient medication safety. This study aimed to assess the primary labeling of medicines manufactured and marketed by Nepalese pharmaceutical industries. Methods: We assessed the primary labeling of all medicines available at the pharmacy of Chitwan Medical College Teaching Hospital (CMCTH), Chitwan, Nepal, between November 2017 to December 2017. Medicines were assessed as required by Drug Standard Regulation, 2043 (1986 AD) of Nepal. Appropriate classification of all the medicines and content of over-the-counter (OTC) medicines (where certain information should be in Nepali language) was also assessed. Descriptive statistics was performed. Results: Seven hundred fifty-nine medicines manufactured by 37 Nepalese pharmaceutical industries were assessed. While all pharmaceutical products had the name of the drug (brand), only76.8% of them stated drug quantity. Almost all products were found to declare category of the drug, with only a few (4.1%) mentioning the sub-category. The system of medicine was stated in 9.9% of the products. Active ingredients and their quantity, manufacturer's information, serial number for the production of drug and the date of production, storing methods, and information on the quantity used were mentioned in almost all the products. Similarly, all the products had batch number and the date of expiry. But, 11% of the products lacked the name of pharmacopoeia to which the drug belongs and all the products lacked the serial number for establishment of pharmaceutical industry. Similarly, 5.3% of the products did not list their price, and 2.4% of prescription medicines lacked caution labeling. Unfortunately, the majority of the products (84.4%) did not provide the directions of use. Appropriate drug classification was found in 89.6% of products. None of the over-the-counter medicines totally adhered to the requirements for writing ce
Published: 2018

26. Assessment of primary labeling of medicines manufactured by Nepalese pharmaceutical industries.

Author: Poudel, RS, Shrestha, S, Thapa, S, Poudel, BK, Chhetri, M, Poudel, RS, Shrestha, S, Thapa, S, Poudel, BK, and Chhetri, M
Abstract: Background: Appropriate labeling of marketed medicines is necessary to fulfill the regulatory provisions and ensure patient medication safety. This study aimed to assess the primary labeling of medicines manufactured and marketed by Nepalese pharmaceutical industries. Methods: We assessed the primary labeling of all medicines available at the pharmacy of Chitwan Medical College Teaching Hospital (CMCTH), Chitwan, Nepal, between November 2017 to December 2017. Medicines were assessed as required by Drug Standard Regulation, 2043 (1986 AD) of Nepal. Appropriate classification of all the medicines and content of over-the-counter (OTC) medicines (where certain information should be in Nepali language) was also assessed. Descriptive statistics was performed. Results: Seven hundred fifty-nine medicines manufactured by 37 Nepalese pharmaceutical industries were assessed. While all pharmaceutical products had the name of the drug (brand), only76.8% of them stated drug quantity. Almost all products were found to declare category of the drug, with only a few (4.1%) mentioning the sub-category. The system of medicine was stated in 9.9% of the products. Active ingredients and their quantity, manufacturer's information, serial number for the production of drug and the date of production, storing methods, and information on the quantity used were mentioned in almost all the products. Similarly, all the products had batch number and the date of expiry. But, 11% of the products lacked the name of pharmacopoeia to which the drug belongs and all the products lacked the serial number for establishment of pharmaceutical industry. Similarly, 5.3% of the products did not list their price, and 2.4% of prescription medicines lacked caution labeling. Unfortunately, the majority of the products (84.4%) did not provide the directions of use. Appropriate drug classification was found in 89.6% of products. None of the over-the-counter medicines totally adhered to the requirements for writing ce
Published: 2018

27. First Dark Matter Search Results from the XENON1T Experiment

Author: Aprile, E., Aalbers, J., Agostini, F., Alfonsi, M., Amaro, F. D., Anthony, M., Arneodo, F., Barrow, P., Baudis, L., Bauermeister, Boris, Benabderrahmane, M. L., Berger, T., Breur, P. A., Brown, A., Brown, E., Bruenner, S., Bruno, G., Budnik, R., Buetikofer, L., Calvén, Jakob, Cardoso, J. M. R., Cervantes, M., Cichon, D., Coderre, D., Colijn, A. P., Conrad, Jan, Cussonneau, J. P., Decowski, M. P., de Perio, P., Di Gangi, P., Di Giovanni, A., Diglio, S., Eurin, G., Fei, J., Ferella, Alfredo D., Fieguth, A., Fulgione, W., Rosso, A. Gallo, Galloway, M., Gao, F., Garbini, M., Gardner, R., Geis, C., Goetzke, L. W., Grandi, L., Greene, Z., Grignon, C., Hasterok, C., Hogenbirk, E., Howlett, J., Itay, R., Kaminsky, B., Kazama, S., Kessler, G., Kish, A., Landsman, H., Lang, R. F., Lellouch, D., Levinson, L., Lin, Q., Lindemann, S., Lindner, M., Lombardi, F., Lopes, J. A. M., Manfredini, A., Maris, I., Undagoitia, T. Marrodan, Masbou, J., Massoli, F. V., Masson, D., Mayani, D., Messina, M., Micheneau, K., Molinario, A., Morå, Knut, Murra, M., Naganoma, J., Ni, K., Oberlack, U., Pakarha, P., Pelssers, Bart, Persiani, R., Piastra, F., Pienaar, J., Pizzella, V., Piro, M. -C., Plante, G., Priel, N., Rauch, L., Reichard, S., Reuter, C., Riedel, B., Rizzo, A., Rosendahl, S., Rupp, N., Saldanha, R., dos Santos, J. M. F., Sartorelli, G., Scheibelhut, M., Schindler, S., Schreiner, J., Schumann, M., Lavina, L. Scotto, Selvi, M., Shagin, P., Shockley, E., Silva, M., Simgen, H., von Sivers, M., Stein, A., Thapa, S., Thers, D., Tiseni, A., Trinchero, G., Tunnell, C., Vargas, M., Upole, N., Wang, H., Wang, Z., Wei, Y., Weinheimer, C., Wulf, J., Ye, J., Zhang, Y., Zhu, T., Aprile, E., Aalbers, J., Agostini, F., Alfonsi, M., Amaro, F. D., Anthony, M., Arneodo, F., Barrow, P., Baudis, L., Bauermeister, Boris, Benabderrahmane, M. L., Berger, T., Breur, P. A., Brown, A., Brown, E., Bruenner, S., Bruno, G., Budnik, R., Buetikofer, L., Calvén, Jakob, Cardoso, J. M. R., Cervantes, M., Cichon, D., Coderre, D., Colijn, A. P., Conrad, Jan, Cussonneau, J. P., Decowski, M. P., de Perio, P., Di Gangi, P., Di Giovanni, A., Diglio, S., Eurin, G., Fei, J., Ferella, Alfredo D., Fieguth, A., Fulgione, W., Rosso, A. Gallo, Galloway, M., Gao, F., Garbini, M., Gardner, R., Geis, C., Goetzke, L. W., Grandi, L., Greene, Z., Grignon, C., Hasterok, C., Hogenbirk, E., Howlett, J., Itay, R., Kaminsky, B., Kazama, S., Kessler, G., Kish, A., Landsman, H., Lang, R. F., Lellouch, D., Levinson, L., Lin, Q., Lindemann, S., Lindner, M., Lombardi, F., Lopes, J. A. M., Manfredini, A., Maris, I., Undagoitia, T. Marrodan, Masbou, J., Massoli, F. V., Masson, D., Mayani, D., Messina, M., Micheneau, K., Molinario, A., Morå, Knut, Murra, M., Naganoma, J., Ni, K., Oberlack, U., Pakarha, P., Pelssers, Bart, Persiani, R., Piastra, F., Pienaar, J., Pizzella, V., Piro, M. -C., Plante, G., Priel, N., Rauch, L., Reichard, S., Reuter, C., Riedel, B., Rizzo, A., Rosendahl, S., Rupp, N., Saldanha, R., dos Santos, J. M. F., Sartorelli, G., Scheibelhut, M., Schindler, S., Schreiner, J., Schumann, M., Lavina, L. Scotto, Selvi, M., Shagin, P., Shockley, E., Silva, M., Simgen, H., von Sivers, M., Stein, A., Thapa, S., Thers, D., Tiseni, A., Trinchero, G., Tunnell, C., Vargas, M., Upole, N., Wang, H., Wang, Z., Wei, Y., Weinheimer, C., Wulf, J., Ye, J., Zhang, Y., and Zhu, T.
Abstract: We report the first dark matter search results from XENON1T, a similar to 2000-kg-target-mass dual-phase (liquid-gas) xenon time projection chamber in operation at the Laboratori Nazionali del Gran Sasso in Italy and the first ton-scale detector of this kind. The blinded search used 34.2 live days of data acquired between November 2016 and January 2017. Inside the (1042 +/- 12)-kg fiducial mass and in the [5, 40] keV(nr) energy range of interest for weakly interacting massive particle (WIMP) dark matter searches, the electronic recoil background was (1.93 +/- 0.25) x 10(-4) events/(kg x day x keV(ee)), the lowest ever achieved in such a dark matter detector. A profile likelihood analysis shows that the data are consistent with the background-only hypothesis. We derive the most stringent exclusion limits on the spin-independent WIMP-nucleon interaction cross section for WIMP masses above 10 GeV/c(2), with a minimum of 7.7 x 10(-47) cm(2) for 35-GeV/c(2) WIMPs at 90% C.L.
Published: 2017
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28. First Dark Matter Search Results from the XENON1T Experiment

Author: Aprile, E., Aalbers, J., Agostini, F., Alfonsi, M., Amaro, F. D., Anthony, M., Arneodo, F., Barrow, P., Baudis, L., Bauermeister, B., Benabderrahmane, M. L., Berger, T., Breur, P. A., Brown, A., Brown, E., Bruenner, S., Bruno, G., Budnik, R., Bütikofer, L., Calvén, J., Cardoso, J. M. R., Cervantes, M., Cichon, D., Coderre, D., Colijn, A. P., Conrad, J., Cussonneau, J. P., Decowski, M. P., de Perio, P., Di Gangi, P., Di Giovanni, A., Diglio, S., Eurin, G., Fei, J., Ferella, A. D., Fieguth, A., Fulgione, W., Rosso, A. Gallo, Galloway, M., Gao, F., Garbini, M., Gardner, R., Geis, C., Goetzke, L. W., Grandi, L., Greene, Z., Grignon, C., Hasterok, C., Hogenbirk, E., Howlett, J., Itay, R., Kaminsky, B., Kazama, S., Kessler, G., Kish, A., Landsman, H., Lang, R. F., Lellouch, D., Levinson, L., Lin, Q., Lindemann, S., Lindner, M., Lombardi, F., Lopes, J. A. M., Manfredini, A., Mariş, I., Undagoitia, T. Marrodán, Masbou, J., Massoli, F. V., Masson, D., Mayani, D., Messina, M., Micheneau, K., Molinario, A., Morå, K., Murra, M., Naganoma, J., Ni, K., Oberlack, U., Pakarha, P., Pelssers, B., Persiani, R., Piastra, F., Pienaar, J., Pizzella, V., Piro, M. -C., Plante, G., Priel, N., Rauch, L., Reichard, S., Reuter, C., Riedel, B., Rizzo, A., Rosendahl, S., Rupp, N., Saldanha, R., Santos, J. M. F. dos, Sartorelli, G., Scheibelhut, M., Schindler, S., Schreiner, J., Schumann, M., Lavina, L. Scotto, Selvi, M., Shagin, P., Shockley, E., Silva, M., Simgen, H., Sivers, M. v., Stein, A., Thapa, S., Thers, D., Tiseni, A., Trinchero, G., Tunnell, C., Vargas, M., Upole, N., Wang, H., Wang, Z., Wei, Y., Weinheimer, C., Wulf, J., Ye, J., Zhang, Y., Zhu, T., Aprile, E., Aalbers, J., Agostini, F., Alfonsi, M., Amaro, F. D., Anthony, M., Arneodo, F., Barrow, P., Baudis, L., Bauermeister, B., Benabderrahmane, M. L., Berger, T., Breur, P. A., Brown, A., Brown, E., Bruenner, S., Bruno, G., Budnik, R., Bütikofer, L., Calvén, J., Cardoso, J. M. R., Cervantes, M., Cichon, D., Coderre, D., Colijn, A. P., Conrad, J., Cussonneau, J. P., Decowski, M. P., de Perio, P., Di Gangi, P., Di Giovanni, A., Diglio, S., Eurin, G., Fei, J., Ferella, A. D., Fieguth, A., Fulgione, W., Rosso, A. Gallo, Galloway, M., Gao, F., Garbini, M., Gardner, R., Geis, C., Goetzke, L. W., Grandi, L., Greene, Z., Grignon, C., Hasterok, C., Hogenbirk, E., Howlett, J., Itay, R., Kaminsky, B., Kazama, S., Kessler, G., Kish, A., Landsman, H., Lang, R. F., Lellouch, D., Levinson, L., Lin, Q., Lindemann, S., Lindner, M., Lombardi, F., Lopes, J. A. M., Manfredini, A., Mariş, I., Undagoitia, T. Marrodán, Masbou, J., Massoli, F. V., Masson, D., Mayani, D., Messina, M., Micheneau, K., Molinario, A., Morå, K., Murra, M., Naganoma, J., Ni, K., Oberlack, U., Pakarha, P., Pelssers, B., Persiani, R., Piastra, F., Pienaar, J., Pizzella, V., Piro, M. -C., Plante, G., Priel, N., Rauch, L., Reichard, S., Reuter, C., Riedel, B., Rizzo, A., Rosendahl, S., Rupp, N., Saldanha, R., Santos, J. M. F. dos, Sartorelli, G., Scheibelhut, M., Schindler, S., Schreiner, J., Schumann, M., Lavina, L. Scotto, Selvi, M., Shagin, P., Shockley, E., Silva, M., Simgen, H., Sivers, M. v., Stein, A., Thapa, S., Thers, D., Tiseni, A., Trinchero, G., Tunnell, C., Vargas, M., Upole, N., Wang, H., Wang, Z., Wei, Y., Weinheimer, C., Wulf, J., Ye, J., Zhang, Y., and Zhu, T.
Abstract: We report the first dark matter search results from XENON1T, a $\sim$2000-kg-target-mass dual-phase (liquid-gas) xenon time projection chamber in operation at the Laboratori Nazionali del Gran Sasso in Italy and the first ton-scale detector of this kind. The blinded search used 34.2 live days of data acquired between November 2016 and January 2017. Inside the (1042$\pm$12) kg fiducial mass and in the [5, 40] $\mathrm{keV}_{\mathrm{nr}}$ energy range of interest for WIMP dark matter searches, the electronic recoil background was $(1.93 \pm 0.25) \times 10^{-4}$ events/(kg $\times$ day $\times \mathrm{keV}_{\mathrm{ee}}$), the lowest ever achieved in a dark matter detector. A profile likelihood analysis shows that the data is consistent with the background-only hypothesis. We derive the most stringent exclusion limits on the spin-independent WIMP-nucleon interaction cross section for WIMP masses above 10 GeV/c${}^2$, with a minimum of 7.7 $\times 10^{-47}$ cm${}^2$ for 35-GeV/c${}^2$ WIMPs at 90% confidence level., Comment: 6 pages, 4 figures, v2 data upload Fig 2/4, v3 as accepted by PRL with textual clarifications, v4 data upload Fig 1
Published: 2017
Full Text: View/download PDF

29. First Dark Matter Search Results from the XENON1T Experiment

Author: Aprile, E., Aalbers, J., Agostini, F., Alfonsi, M., Amaro, F. D., Anthony, M., Arneodo, F., Barrow, P., Baudis, L., Bauermeister, B., Benabderrahmane, M. L., Berger, T., Breur, P. A., Brown, A., Brown, E., Bruenner, S., Bruno, G., Budnik, R., Bütikofer, L., Calvén, J., Cardoso, J. M. R., Cervantes, M., Cichon, D., Coderre, D., Colijn, A. P., Conrad, J., Cussonneau, J. P., Decowski, M. P., de Perio, P., Di Gangi, P., Di Giovanni, A., Diglio, S., Eurin, G., Fei, J., Ferella, A. D., Fieguth, A., Fulgione, W., Rosso, A. Gallo, Galloway, M., Gao, F., Garbini, M., Gardner, R., Geis, C., Goetzke, L. W., Grandi, L., Greene, Z., Grignon, C., Hasterok, C., Hogenbirk, E., Howlett, J., Itay, R., Kaminsky, B., Kazama, S., Kessler, G., Kish, A., Landsman, H., Lang, R. F., Lellouch, D., Levinson, L., Lin, Q., Lindemann, S., Lindner, M., Lombardi, F., Lopes, J. A. M., Manfredini, A., Mariş, I., Undagoitia, T. Marrodán, Masbou, J., Massoli, F. V., Masson, D., Mayani, D., Messina, M., Micheneau, K., Molinario, A., Morå, K., Murra, M., Naganoma, J., Ni, K., Oberlack, U., Pakarha, P., Pelssers, B., Persiani, R., Piastra, F., Pienaar, J., Pizzella, V., Piro, M. -C., Plante, G., Priel, N., Rauch, L., Reichard, S., Reuter, C., Riedel, B., Rizzo, A., Rosendahl, S., Rupp, N., Saldanha, R., Santos, J. M. F. dos, Sartorelli, G., Scheibelhut, M., Schindler, S., Schreiner, J., Schumann, M., Lavina, L. Scotto, Selvi, M., Shagin, P., Shockley, E., Silva, M., Simgen, H., Sivers, M. v., Stein, A., Thapa, S., Thers, D., Tiseni, A., Trinchero, G., Tunnell, C., Vargas, M., Upole, N., Wang, H., Wang, Z., Wei, Y., Weinheimer, C., Wulf, J., Ye, J., Zhang, Y., Zhu, T., Aprile, E., Aalbers, J., Agostini, F., Alfonsi, M., Amaro, F. D., Anthony, M., Arneodo, F., Barrow, P., Baudis, L., Bauermeister, B., Benabderrahmane, M. L., Berger, T., Breur, P. A., Brown, A., Brown, E., Bruenner, S., Bruno, G., Budnik, R., Bütikofer, L., Calvén, J., Cardoso, J. M. R., Cervantes, M., Cichon, D., Coderre, D., Colijn, A. P., Conrad, J., Cussonneau, J. P., Decowski, M. P., de Perio, P., Di Gangi, P., Di Giovanni, A., Diglio, S., Eurin, G., Fei, J., Ferella, A. D., Fieguth, A., Fulgione, W., Rosso, A. Gallo, Galloway, M., Gao, F., Garbini, M., Gardner, R., Geis, C., Goetzke, L. W., Grandi, L., Greene, Z., Grignon, C., Hasterok, C., Hogenbirk, E., Howlett, J., Itay, R., Kaminsky, B., Kazama, S., Kessler, G., Kish, A., Landsman, H., Lang, R. F., Lellouch, D., Levinson, L., Lin, Q., Lindemann, S., Lindner, M., Lombardi, F., Lopes, J. A. M., Manfredini, A., Mariş, I., Undagoitia, T. Marrodán, Masbou, J., Massoli, F. V., Masson, D., Mayani, D., Messina, M., Micheneau, K., Molinario, A., Morå, K., Murra, M., Naganoma, J., Ni, K., Oberlack, U., Pakarha, P., Pelssers, B., Persiani, R., Piastra, F., Pienaar, J., Pizzella, V., Piro, M. -C., Plante, G., Priel, N., Rauch, L., Reichard, S., Reuter, C., Riedel, B., Rizzo, A., Rosendahl, S., Rupp, N., Saldanha, R., Santos, J. M. F. dos, Sartorelli, G., Scheibelhut, M., Schindler, S., Schreiner, J., Schumann, M., Lavina, L. Scotto, Selvi, M., Shagin, P., Shockley, E., Silva, M., Simgen, H., Sivers, M. v., Stein, A., Thapa, S., Thers, D., Tiseni, A., Trinchero, G., Tunnell, C., Vargas, M., Upole, N., Wang, H., Wang, Z., Wei, Y., Weinheimer, C., Wulf, J., Ye, J., Zhang, Y., and Zhu, T.
Abstract: We report the first dark matter search results from XENON1T, a $\sim$2000-kg-target-mass dual-phase (liquid-gas) xenon time projection chamber in operation at the Laboratori Nazionali del Gran Sasso in Italy and the first ton-scale detector of this kind. The blinded search used 34.2 live days of data acquired between November 2016 and January 2017. Inside the (1042$\pm$12) kg fiducial mass and in the [5, 40] $\mathrm{keV}_{\mathrm{nr}}$ energy range of interest for WIMP dark matter searches, the electronic recoil background was $(1.93 \pm 0.25) \times 10^{-4}$ events/(kg $\times$ day $\times \mathrm{keV}_{\mathrm{ee}}$), the lowest ever achieved in a dark matter detector. A profile likelihood analysis shows that the data is consistent with the background-only hypothesis. We derive the most stringent exclusion limits on the spin-independent WIMP-nucleon interaction cross section for WIMP masses above 10 GeV/c${}^2$, with a minimum of 7.7 $\times 10^{-47}$ cm${}^2$ for 35-GeV/c${}^2$ WIMPs at 90% confidence level., Comment: 6 pages, 4 figures, v2 data upload Fig 2/4, v3 as accepted by PRL with textual clarifications, v4 data upload Fig 1
Published: 2017
Full Text: View/download PDF

30. First Dark Matter Search Results from the XENON1T Experiment

Author: Aprile, E., Aalbers, J., Agostini, F., Alfonsi, M., Amaro, F. D., Anthony, M., Arneodo, F., Barrow, P., Baudis, L., Bauermeister, B., Benabderrahmane, M. L., Berger, T., Breur, P. A., Brown, A., Brown, E., Bruenner, S., Bruno, G., Budnik, R., Bütikofer, L., Calvén, J., Cardoso, J. M. R., Cervantes, M., Cichon, D., Coderre, D., Colijn, A. P., Conrad, J., Cussonneau, J. P., Decowski, M. P., de Perio, P., Di Gangi, P., Di Giovanni, A., Diglio, S., Eurin, G., Fei, J., Ferella, A. D., Fieguth, A., Fulgione, W., Rosso, A. Gallo, Galloway, M., Gao, F., Garbini, M., Gardner, R., Geis, C., Goetzke, L. W., Grandi, L., Greene, Z., Grignon, C., Hasterok, C., Hogenbirk, E., Howlett, J., Itay, R., Kaminsky, B., Kazama, S., Kessler, G., Kish, A., Landsman, H., Lang, R. F., Lellouch, D., Levinson, L., Lin, Q., Lindemann, S., Lindner, M., Lombardi, F., Lopes, J. A. M., Manfredini, A., Mariş, I., Undagoitia, T. Marrodán, Masbou, J., Massoli, F. V., Masson, D., Mayani, D., Messina, M., Micheneau, K., Molinario, A., Morå, K., Murra, M., Naganoma, J., Ni, K., Oberlack, U., Pakarha, P., Pelssers, B., Persiani, R., Piastra, F., Pienaar, J., Pizzella, V., Piro, M. -C., Plante, G., Priel, N., Rauch, L., Reichard, S., Reuter, C., Riedel, B., Rizzo, A., Rosendahl, S., Rupp, N., Saldanha, R., Santos, J. M. F. dos, Sartorelli, G., Scheibelhut, M., Schindler, S., Schreiner, J., Schumann, M., Lavina, L. Scotto, Selvi, M., Shagin, P., Shockley, E., Silva, M., Simgen, H., Sivers, M. v., Stein, A., Thapa, S., Thers, D., Tiseni, A., Trinchero, G., Tunnell, C., Vargas, M., Upole, N., Wang, H., Wang, Z., Wei, Y., Weinheimer, C., Wulf, J., Ye, J., Zhang, Y., Zhu, T., Aprile, E., Aalbers, J., Agostini, F., Alfonsi, M., Amaro, F. D., Anthony, M., Arneodo, F., Barrow, P., Baudis, L., Bauermeister, B., Benabderrahmane, M. L., Berger, T., Breur, P. A., Brown, A., Brown, E., Bruenner, S., Bruno, G., Budnik, R., Bütikofer, L., Calvén, J., Cardoso, J. M. R., Cervantes, M., Cichon, D., Coderre, D., Colijn, A. P., Conrad, J., Cussonneau, J. P., Decowski, M. P., de Perio, P., Di Gangi, P., Di Giovanni, A., Diglio, S., Eurin, G., Fei, J., Ferella, A. D., Fieguth, A., Fulgione, W., Rosso, A. Gallo, Galloway, M., Gao, F., Garbini, M., Gardner, R., Geis, C., Goetzke, L. W., Grandi, L., Greene, Z., Grignon, C., Hasterok, C., Hogenbirk, E., Howlett, J., Itay, R., Kaminsky, B., Kazama, S., Kessler, G., Kish, A., Landsman, H., Lang, R. F., Lellouch, D., Levinson, L., Lin, Q., Lindemann, S., Lindner, M., Lombardi, F., Lopes, J. A. M., Manfredini, A., Mariş, I., Undagoitia, T. Marrodán, Masbou, J., Massoli, F. V., Masson, D., Mayani, D., Messina, M., Micheneau, K., Molinario, A., Morå, K., Murra, M., Naganoma, J., Ni, K., Oberlack, U., Pakarha, P., Pelssers, B., Persiani, R., Piastra, F., Pienaar, J., Pizzella, V., Piro, M. -C., Plante, G., Priel, N., Rauch, L., Reichard, S., Reuter, C., Riedel, B., Rizzo, A., Rosendahl, S., Rupp, N., Saldanha, R., Santos, J. M. F. dos, Sartorelli, G., Scheibelhut, M., Schindler, S., Schreiner, J., Schumann, M., Lavina, L. Scotto, Selvi, M., Shagin, P., Shockley, E., Silva, M., Simgen, H., Sivers, M. v., Stein, A., Thapa, S., Thers, D., Tiseni, A., Trinchero, G., Tunnell, C., Vargas, M., Upole, N., Wang, H., Wang, Z., Wei, Y., Weinheimer, C., Wulf, J., Ye, J., Zhang, Y., and Zhu, T.
Abstract: We report the first dark matter search results from XENON1T, a $\sim$2000-kg-target-mass dual-phase (liquid-gas) xenon time projection chamber in operation at the Laboratori Nazionali del Gran Sasso in Italy and the first ton-scale detector of this kind. The blinded search used 34.2 live days of data acquired between November 2016 and January 2017. Inside the (1042$\pm$12) kg fiducial mass and in the [5, 40] $\mathrm{keV}_{\mathrm{nr}}$ energy range of interest for WIMP dark matter searches, the electronic recoil background was $(1.93 \pm 0.25) \times 10^{-4}$ events/(kg $\times$ day $\times \mathrm{keV}_{\mathrm{ee}}$), the lowest ever achieved in a dark matter detector. A profile likelihood analysis shows that the data is consistent with the background-only hypothesis. We derive the most stringent exclusion limits on the spin-independent WIMP-nucleon interaction cross section for WIMP masses above 10 GeV/c${}^2$, with a minimum of 7.7 $\times 10^{-47}$ cm${}^2$ for 35-GeV/c${}^2$ WIMPs at 90% confidence level., Comment: 6 pages, 4 figures, v2 data upload Fig 2/4, v3 as accepted by PRL with textual clarifications, v4 data upload Fig 1
Published: 2017
Full Text: View/download PDF

31. Retrofitting design of Kathmandu University library building after Gorkha earthquake 2015

Author: Pradhan, P.M., Adhikari, R., Dahal, A., Shrestha, A., Subedi, D.L, Thapa, S., Kharel, P., Corresponding author, Assistant Professor & Acting Head of Department, Department of Civil and Geomatics Engineering, Kathmandu University, NEPAL, Lecturer in Department of Civil and Geomatics Engineering, Kathmandu University, NEPAL, Department of Civil and Geomatics Engineering, Kathmandu University, NEPAL, Department of Civil and Geomatics Engineering, Kathmandu University, Pradhan, P.M., Adhikari, R., Dahal, A., Shrestha, A., Subedi, D.L, Thapa, S., Kharel, P., Corresponding author, Assistant Professor & Acting Head of Department, Department of Civil and Geomatics Engineering, Kathmandu University, NEPAL, Lecturer in Department of Civil and Geomatics Engineering, Kathmandu University, NEPAL, Department of Civil and Geomatics Engineering, Kathmandu University, NEPAL, and Department of Civil and Geomatics Engineering, Kathmandu University
Published: 2016

32. Caregivers' Attitude towards People with Mental Illness and Perceived Stigma: A Cross-Sectional Study in a Tertiary Hospital in Nepal

Author: Maulik, PK, Neupane, D, Dhakal, S, Thapa, S, Bhandari, PM, Mishra, SR, Maulik, PK, Neupane, D, Dhakal, S, Thapa, S, Bhandari, PM, and Mishra, SR
Abstract: BACKGROUND: Mental illness is stigmatized in most of the communities and people with such illness are often subjected to defame. Stigma impairs an individual's and their caregiver's physical, social and emotional wellbeing, and health-seeking behavior. Sufficient literature on how often the caregivers of people with mental illness from low and middle-income countries are stigmatized and how they perceive people with mental illness is unavailable. In this study, we examined caregivers' attitude towards people with mental illness and perceived stigma. METHODS: We conducted face-to-face interviews with 170 caregivers in an outpatient clinic of a hospital in Nepal using a structured questionnaire. We calculated median and inter-quartile range of the attitude and perceived stigma scores. To assess the correlates, Kruskal Wallis H test and Mann Whitney U test were carried out. RESULTS: Overall median score for the domains: attitude (score range: 18-90) and perceived stigma (score range: 12-60) were 42 and 28 respectively, inter-quartile range being 8 each. Attitude score differed significantly by the sex of caregiver (p<0.05), educational status of caregiver (p<0.001), sex of patient (p<0.05) and type of mental illness (p<0.05). Perceived stigma score varied significantly by caregiver's sex (p<0.05), marital status (p<0.001), educational status (p<0.001), occupation (p<0.05), relation with the patient (p<0.005) and use of alternative treatment modalities (p<0.05). CONCLUSION: Sex of participant, educational status, sex of patient and type of mental illness were the correlates of attitude towards mental illness. Similarly, sex of participant, marital status, educational status, occupation, caregiver's relation with patient and use of alternative treatment modalities were correlates of perceived stigma. Findings of this study suggest that interventions targeting these high-risk populations might be beneficial to help build a positive attitude and overcome the perceived soci
Published: 2016

33. Evaluation of feed safety aspects in feeding organic layers with fresh house fly larvae (Musca domestica) reared in poultry manure

Author: Nordentoft, Steen, Fischer, C., Hald, Birthe, Enemark, Heidi, Thapa, S., Bjerrum, L., Nordentoft, Steen, Fischer, C., Hald, Birthe, Enemark, Heidi, Thapa, S., and Bjerrum, L.
Published: 2014

34. Development of PV grid-connected plants in Nepal. A feasibility study and training programme co-financed by REPIC

Author: Chianese, D., Pittet, D., Shrestha, J.N., Sharma, D., Zahnd, A., Upadhyaya, M.R., Thapa, S., Sanjel, N., Shah, M., Chianese, D., Pittet, D., Shrestha, J.N., Sharma, D., Zahnd, A., Upadhyaya, M.R., Thapa, S., Sanjel, N., and Shah, M.
Abstract: This project was co-funded by REPIC and SUPSI. It was achieved through the close collaboration between SUPSI and two Nepalese partner teams: the CES of the Tribhuvan University together with NSES, and Kathmandu University alongside RIDS-Nepal. The project was implemented between October 2008 and June 2010. Although connecting PV modules to the main electric grid is by far the most rational, economical and efficient way to install this technology, it appears that, like in many other developing and transition countries, PV technology has so far been applied in Nepal exclusively through standalone plants (NEA, 2008). Such plants are used in several remote areas of the country and provide very satisfactory service to the rural populations (Zahnd, McKay, & Komp, 2006). However, the urban regions of Nepal, which already have access to the national electricity grid, are so far making use of PV technology without the added advantage of a connection to the grid. As exposed in chapter four, Nepal benefits from extremely favourable climatic conditions for exploiting PV technology. Moreover, despite its extraordinary potential for the production of hydropower, a lack of investments, political instability and the increase in energy demands have brought the country in a severe energy crisis, with as much as sixteen hours of load shedding per day during spring 2009. Solutions and ways out of the energy crisis will certainly be found by diversifying the electricity sources, so as to increase the production capacity in the short and long term, with –hopefully– careful consideration for global sustainability criteria. Grid-connected PV technology could be part of the “package” of Nepal’s future electricity supply scheme, but the conditions and criteria to make it applicable in the given context are manifold and influenced by technical, institutional and economic aspects. These will be analysed in the present work in order to assess its feasibility. Although the investigation for the
Published: 2010

35. Structural and spectroscopic properties of AlN layers grown by MOVPE

Author: Thapa, S. B., Kirchner, C., Scholz, F., Prinz, G. M., Thonke, K., Sauer, R., Chuvilin, A., Biskupek, J., Kaiser, U., Hofstetter, Daniel, Thapa, S. B., Kirchner, C., Scholz, F., Prinz, G. M., Thonke, K., Sauer, R., Chuvilin, A., Biskupek, J., Kaiser, U., and Hofstetter, Daniel
Abstract: The effects on surface morphology, crystal quality, and growth rate of undoped AlN layers grown on c-plane sapphire substrates due to the changes in growth parameters, such as V–III ratio, N2–H2 ratio, and growth temperature in LP-MOVPE are studied here. The optimized growth process resulted in an almost flat surface morphology with a significantly reduced number of hexagonal pits (3 x 107 cm-2) and good crystalline quality having a rms value of roughness of 0.4 nm measured by atomic force microscopy and a high resolution X-ray diffraction (HRXRD) FWHM value for (0 0 0 2) reflection of 200 arcsecs. The threading dislocation density of the AlN layer is estimated approx. 109 cm-2 from cross-sectional transmission electron microscopy (TEM) measurements. Additionally, these optimized samples show a strong donor-bound exciton luminescence signal with a FWHM of 20 meV. Furthermore, small period AlN/GaN superlattice structures with excellent uniformity were grown, as proven by our HRXRD and TEM studies.
Published: 2008

36. Integrated management of water, forest and land resources in Nepal: opportunities for improved livelihood

Author: Pant, Dhruba, Thapa, S., Singh, A., Bhattarai, Madhusudan, David, S., Pant, Dhruba, Thapa, S., Singh, A., Bhattarai, Madhusudan, and David, S.

37. Integrated management of water, forest and land resources in Nepal: opportunities for improved livelihood

Author: Pant, D., Thapa, S., Singh, A., Bhattarai, M., Pant, D., Thapa, S., Singh, A., and Bhattarai, M.

38. Structural and spectroscopic properties of AlN layers grown by MOVPE

Author: Thapa, S. B., Kirchner, C., Scholz, F., Prinz, G. M., Thonke, K., Sauer, R., Chuvilin, A., Biskupek, J., Kaiser, U., Hofstetter, Daniel, Thapa, S. B., Kirchner, C., Scholz, F., Prinz, G. M., Thonke, K., Sauer, R., Chuvilin, A., Biskupek, J., Kaiser, U., and Hofstetter, Daniel
Abstract: The effects on surface morphology, crystal quality, and growth rate of undoped AlN layers grown on c-plane sapphire substrates due to the changes in growth parameters, such as V–III ratio, N2–H2 ratio, and growth temperature in LP-MOVPE are studied here. The optimized growth process resulted in an almost flat surface morphology with a significantly reduced number of hexagonal pits (3 x 107 cm-2) and good crystalline quality having a rms value of roughness of 0.4 nm measured by atomic force microscopy and a high resolution X-ray diffraction (HRXRD) FWHM value for (0 0 0 2) reflection of 200 arcsecs. The threading dislocation density of the AlN layer is estimated approx. 109 cm-2 from cross-sectional transmission electron microscopy (TEM) measurements. Additionally, these optimized samples show a strong donor-bound exciton luminescence signal with a FWHM of 20 meV. Furthermore, small period AlN/GaN superlattice structures with excellent uniformity were grown, as proven by our HRXRD and TEM studies.

39. Integrated management of water, forest and land resources in Nepal: opportunities for improved livelihood

Author: Pant, Dhruba, Thapa, S., Singh, A., Bhattarai, Madhusudan, David, S., Pant, Dhruba, Thapa, S., Singh, A., Bhattarai, Madhusudan, and David, S.

40. Integrated management of water, forest and land resources in Nepal: opportunities for improved livelihood

Author: Pant, D., Thapa, S., Singh, A., Bhattarai, M., Pant, D., Thapa, S., Singh, A., and Bhattarai, M.

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