Search

Your search keyword '"Wood, DA"' showing total 11 results
Start Over Author "Wood, DA" Publication Type Electronic Resources
11 results on '"Wood, DA"'

1. Water-power scenarios to 2033: A mixed model

Author

Hafezi, R, Wood, DA, Alipour, M, Taghikhah, FR, Hafezi, R, Wood, DA, Alipour, M, and Taghikhah, FR

Abstract

The balancing of energy and water supply-demand involves a challenging issue. Policymakers at both global and national levels are striving to ensure the security of energy and water supply while supporting economic growth. This study investigates the nexus between water and power and explores potential future directions at global and national perspectives. It considers the case of Iran, as a resource-rich developing economy, to assess real-world influences and potential outcomes. The research proposes an enhanced layered uncertainties scenario synthesizing model to develop and evaluate plausible futures within a 10-year planning horizon (2033). The model employs a novel data-gathering procedure based on experts’ inputs and intuitionistic fuzzy averaging to facilitate reliable judgments in a highly uncertain environment. Findings reveal that, from the global perspective, an energy transition is likely to gain momentum during the next decade, but the water intensity (quantity of water supplied per unit of GDP) is expected to gradually decrease. Providing reliable and secured electricity and water supply, especially for the less developed economies is likely to become an increasingly challenging matter, hindering their potential financial and technological development. The period to 2033 in Iran is expected to be shaped by political issues and international sanctions, making them the most significant future drivers. These factors are likely to have a substantial impact on Iran's decisions regarding energy and water development, as they may affect foreign investment, the cost of money, and water competition diplomacy.

Published
2023

2. The ChatGPT Artificial Intelligence Chatbot: How Well Does It Answer Accounting Assessment Questions?

Author

Wood, DA, Achhpilia, MP, Adams, MT, Aghazadeh, S, Akinyele, K, Akpan, M, Allee, KD, Allen, AM, Almer, ED, Ames, D, Arity, V, Barr-Pulliam, D, Basoglu, KA, Belnap, A, Bentley, JW, Berg, T, Berglund, NR, Berry, E, Bhandari, A, Bhuyan, MNH, Black, PW, Blondeel, E, Bond, D, Bonrath, A, Borthick, AF, Boyle, ES, Bradford, M, Brandon, DM, Brazel, JF, Brockbank, BG, Burger, M, Byzalov, D, Cannon, JN, Caro, C, Carr, AH, Cathey, J, Cating, R, Charron, K, Chavez, S, Chen, J, Chen, JC, Chen, JW, Cheng, C, Cheng, X, Christensen, BE, Church, KS, Cicone, NJ, Constance, P, Cooper, LA, Correia, CL, Coyne, J, Cram, WA, Curtis, A, Daigle, RJ, Dannemiller, S, Davenport, SA, Dawson, GS, Meyst, KJLD, Dell, S, Demirkan, S, Denison, CA, Desai, H, Desimone, S, Diehl, LM, Dimes, R, Dong, B, Donnelly, A, du Pon, A, Duan, HK, Duffey, A, Dunn, RT, Durkin, MP, Dzuranin, AC, Eberle, RM, Ege, MS, El Mahdy, D, Esplin, A, Eulerich, M, Everaert, P, Farah, N, Farish, L, Favere-Marchesi, M, Fayard, D, Filosa, JR, Ford, M, Franz, DR, Fulmer, BP, Fulmer, S, Furner, ZZ, Gantman, S, Garner, S, Garrett, J, Geng, X, Golden, J, Goldman, W, Gomez, J, Gooley, M, Granitto, SP, Green, KY, Greenman, CL, Gupta, G, Guymon, RN, Hale, K, Harper, CJ, Hartt, SA, Hawk, H, Hawkins, SR, Hawkins, EM, Hay, DC, Heinzelmann, R, Henderson, CD, Hendricks, BE, Heninger, WG, Hill, MS, Holden, N, Holderness, DK, Holt, TP, Hoopes, JL, Hsieh, S-F, Huang, F, Huang, H-W, Huang, T-C, Huels, BW, Hunter, K, Hurley, PJ, Inger, K, Islam, S, Ison, I, Issa, H, Jackson, AB, Jackson, SC, Janvrin, DJ, Jimenez, PD, Johanson, D, Judd, JS, Kawada, BS, Kelton, AS, Kern, S, Kerr, JN, Keune, MB, Kim, MHJ, Knox, BD, Kogan, G, Kotb, A, Krane, R, Kremin, J, Krieg, KS, Kugel, J, Kulset, EM, Kuruppu, C, Laduca, G, Lamberton, BA, Lamboy-Ruiz, MA, Lang, B, Larocque, SA, Larson, MP, Lawson, BP, Lawson, JG, Lee, L, Lenk, MM, Li-Kuehne, M, Liljegren, J, Lin, Y-H, Liu, W-P, Liu, Z, Lock, B, Long, JH, Loraas, T, Lowensohn, S, Loy, TR, Lyngstadaas, H, Maas, W, Macgregor, JE, Madsen, DO, Malone, CL, Margolin, M, Marshall, ME, Martin, RM, Mpofu, CM, Mccoy, C, Mcguigan, NC, Mcswain, DN, Meckfessel, MD, Mellon, MJ, Melton, OS, Mercado, JM, Mitsuda, S, Modugu, K, Moehrle, S, Chaghervand, AM, Mof, K, Moon, JS, Muehlmann, B, Murray, J, Mwaungulu, ES, Myers, N, Naegle, JC, Ndicu, MJ, Nelson, AS, Nguyen, AL, Niederko, T, Nikbakht, E, O'Brien, AD, Ogunade, KM, O'Leary, D, Oler, MJ, Oler, DK, Olsen, KJ, Otalor, JI, Outlaw, KW, Ozlanski, ME, Parlier, J, Paterson, JS, Pearson, CA, Petersen, MJ, Petra, ST, Pickard, MD, Pickerd, J, Pinsker, R, Plante, C, Plec, JM, Iii, RAP, Quick, LA, Raedy, J, Raschke, R, Ravenscraft, J, Richardson, V, Rixom, BA, Robertson, JF, Rock, I, Romney, MA, Rozario, A, Ruff, MF, Rupley, K, Saeedi, A, Saiewitz, A, Salzsieder, LW, Sarkar, S, Saulls, M, Scanlan, TA, Schaefer, TJ, Schaupp, D, Schneider, GP, Seebeck, A, Sellers, RD, Seto, SC, Sevel, R-L, Shan, Y, Sherwood, MG, Singorahardjo, M, Skaftadottir, HK, Skomra, J, Smith, JL, Smith, DO, Smith, J, Snow, MC, Sommerfeldt, RD, Sorensen, KB, Sorensen, TL, Spieler, AC, Stallings, MA, Stallings, L, Stancill, A, Stanley, JD, Stefaniak, CM, Stephens, NM, Stewart, BW, Stratopoulos, TC, Street, DA, Subedi, M, Summers, SL, Sundkvist, CH, Synn, C, Tadesse, A, Tapis, GP, Tassin, K, Taylor, S, Teal, M, Teeter, R, Tharapos, M, Theis, JC, Thomas, J, Thompson, KS, Thornock, TA, Tietz, W, Travalent, AM, Trinkle, BS, Truelson, JM, Turner, MC, Vagner, B, Vakilzadeh, H, Geest, JVD, Pelt, VV, Vandervelde, SD, Vega, J, Vera-Mun, S, Villanueva, B, Vincent, NE, Wagener, M, Walton, S, Warne, RC, V. Watanabe, O, Watson, D, Watson, MW, Weber, J, Weirich, T, West, AN, Wilford, AL, Wilson, AB, Winrow, B, Winrow, T, Winrow, TS, Wiseman, D, Witte, AL, Wood, BD, Wood, J, Woolley, D, Wright, NS, Wu, J, Xiong, XG, Yatsenko, D, Yazzie, CE, Young, GM, Zhang, CA, Zimmerman, AB, Zoet, E, Wood, DA, Achhpilia, MP, Adams, MT, Aghazadeh, S, Akinyele, K, Akpan, M, Allee, KD, Allen, AM, Almer, ED, Ames, D, Arity, V, Barr-Pulliam, D, Basoglu, KA, Belnap, A, Bentley, JW, Berg, T, Berglund, NR, Berry, E, Bhandari, A, Bhuyan, MNH, Black, PW, Blondeel, E, Bond, D, Bonrath, A, Borthick, AF, Boyle, ES, Bradford, M, Brandon, DM, Brazel, JF, Brockbank, BG, Burger, M, Byzalov, D, Cannon, JN, Caro, C, Carr, AH, Cathey, J, Cating, R, Charron, K, Chavez, S, Chen, J, Chen, JC, Chen, JW, Cheng, C, Cheng, X, Christensen, BE, Church, KS, Cicone, NJ, Constance, P, Cooper, LA, Correia, CL, Coyne, J, Cram, WA, Curtis, A, Daigle, RJ, Dannemiller, S, Davenport, SA, Dawson, GS, Meyst, KJLD, Dell, S, Demirkan, S, Denison, CA, Desai, H, Desimone, S, Diehl, LM, Dimes, R, Dong, B, Donnelly, A, du Pon, A, Duan, HK, Duffey, A, Dunn, RT, Durkin, MP, Dzuranin, AC, Eberle, RM, Ege, MS, El Mahdy, D, Esplin, A, Eulerich, M, Everaert, P, Farah, N, Farish, L, Favere-Marchesi, M, Fayard, D, Filosa, JR, Ford, M, Franz, DR, Fulmer, BP, Fulmer, S, Furner, ZZ, Gantman, S, Garner, S, Garrett, J, Geng, X, Golden, J, Goldman, W, Gomez, J, Gooley, M, Granitto, SP, Green, KY, Greenman, CL, Gupta, G, Guymon, RN, Hale, K, Harper, CJ, Hartt, SA, Hawk, H, Hawkins, SR, Hawkins, EM, Hay, DC, Heinzelmann, R, Henderson, CD, Hendricks, BE, Heninger, WG, Hill, MS, Holden, N, Holderness, DK, Holt, TP, Hoopes, JL, Hsieh, S-F, Huang, F, Huang, H-W, Huang, T-C, Huels, BW, Hunter, K, Hurley, PJ, Inger, K, Islam, S, Ison, I, Issa, H, Jackson, AB, Jackson, SC, Janvrin, DJ, Jimenez, PD, Johanson, D, Judd, JS, Kawada, BS, Kelton, AS, Kern, S, Kerr, JN, Keune, MB, Kim, MHJ, Knox, BD, Kogan, G, Kotb, A, Krane, R, Kremin, J, Krieg, KS, Kugel, J, Kulset, EM, Kuruppu, C, Laduca, G, Lamberton, BA, Lamboy-Ruiz, MA, Lang, B, Larocque, SA, Larson, MP, Lawson, BP, Lawson, JG, Lee, L, Lenk, MM, Li-Kuehne, M, Liljegren, J, Lin, Y-H, Liu, W-P, Liu, Z, Lock, B, Long, JH, Loraas, T, Lowensohn, S, Loy, TR, Lyngstadaas, H, Maas, W, Macgregor, JE, Madsen, DO, Malone, CL, Margolin, M, Marshall, ME, Martin, RM, Mpofu, CM, Mccoy, C, Mcguigan, NC, Mcswain, DN, Meckfessel, MD, Mellon, MJ, Melton, OS, Mercado, JM, Mitsuda, S, Modugu, K, Moehrle, S, Chaghervand, AM, Mof, K, Moon, JS, Muehlmann, B, Murray, J, Mwaungulu, ES, Myers, N, Naegle, JC, Ndicu, MJ, Nelson, AS, Nguyen, AL, Niederko, T, Nikbakht, E, O'Brien, AD, Ogunade, KM, O'Leary, D, Oler, MJ, Oler, DK, Olsen, KJ, Otalor, JI, Outlaw, KW, Ozlanski, ME, Parlier, J, Paterson, JS, Pearson, CA, Petersen, MJ, Petra, ST, Pickard, MD, Pickerd, J, Pinsker, R, Plante, C, Plec, JM, Iii, RAP, Quick, LA, Raedy, J, Raschke, R, Ravenscraft, J, Richardson, V, Rixom, BA, Robertson, JF, Rock, I, Romney, MA, Rozario, A, Ruff, MF, Rupley, K, Saeedi, A, Saiewitz, A, Salzsieder, LW, Sarkar, S, Saulls, M, Scanlan, TA, Schaefer, TJ, Schaupp, D, Schneider, GP, Seebeck, A, Sellers, RD, Seto, SC, Sevel, R-L, Shan, Y, Sherwood, MG, Singorahardjo, M, Skaftadottir, HK, Skomra, J, Smith, JL, Smith, DO, Smith, J, Snow, MC, Sommerfeldt, RD, Sorensen, KB, Sorensen, TL, Spieler, AC, Stallings, MA, Stallings, L, Stancill, A, Stanley, JD, Stefaniak, CM, Stephens, NM, Stewart, BW, Stratopoulos, TC, Street, DA, Subedi, M, Summers, SL, Sundkvist, CH, Synn, C, Tadesse, A, Tapis, GP, Tassin, K, Taylor, S, Teal, M, Teeter, R, Tharapos, M, Theis, JC, Thomas, J, Thompson, KS, Thornock, TA, Tietz, W, Travalent, AM, Trinkle, BS, Truelson, JM, Turner, MC, Vagner, B, Vakilzadeh, H, Geest, JVD, Pelt, VV, Vandervelde, SD, Vega, J, Vera-Mun, S, Villanueva, B, Vincent, NE, Wagener, M, Walton, S, Warne, RC, V. Watanabe, O, Watson, D, Watson, MW, Weber, J, Weirich, T, West, AN, Wilford, AL, Wilson, AB, Winrow, B, Winrow, T, Winrow, TS, Wiseman, D, Witte, AL, Wood, BD, Wood, J, Woolley, D, Wright, NS, Wu, J, Xiong, XG, Yatsenko, D, Yazzie, CE, Young, GM, Zhang, CA, Zimmerman, AB, and Zoet, E

Abstract

ABSTRACT ChatGPT, a language-learning model chatbot, has garnered considerable attention for its ability to respond to users’ questions. Using data from 14 countries and 186 institutions, we compare ChatGPT and student performance for 28,085 questions from accounting assessments and textbook test banks. As of January 2023, ChatGPT provides correct answers for 56.5 percent of questions and partially correct answers for an additional 9.4 percent of questions. When considering point values for questions, students significantly outperform ChatGPT with a 76.7 percent average on assessments compared to 47.5 percent for ChatGPT if no partial credit is awarded and 56.5 percent if partial credit is awarded. Still, ChatGPT performs better than the student average for 15.8 percent of assessments when we include partial credit. We provide evidence of how ChatGPT performs on different question types, accounting topics, class levels, open/closed assessments, and test bank questions. We also discuss implications for accounting education and research.

Published
2023

3. Internal audit stigma impairs internal audit outcomes

Author

Eulerich, M, Kremin, J, Saunders, KK, Wood, DA, Eulerich, M, Kremin, J, Saunders, KK, and Wood, DA

Abstract

Prior research finds that the internal audit function (IAF) plays a critical role in organizations, yet there is still a stigma toward the profession. We examine how this stigma affects internal audit outcomes, using three different data sources: survey results from parts of Europe (113 observations) and the United States (124 observations) for the year 2017 and an experiment (65 observations) in 2018. We find that when internal auditors in parts of Europe and the U.S. believe there is a negative stigma about internal auditing, they report negative work outcomes, including less ability to add value, less influence in the organization, more resistance to implementing their recommendations, and more pressure to change audit findings. Our experimental results confirm the survey findings and provide further evidence that negative stigma causes participants to perceive less value in internal audit reports and that internal audit recommendations are less influential in decision-making. Taken together, the results suggest that negative perceptions of internal audit have a significant impact on the profession

Published
2021

4. Transcatheter Replacement of Transcatheter Versus Surgically Implanted Aortic Valve Bioprostheses

Author

Landes, U, Sathananthan, J, Witberg, G, de Backer, O, Sondergaard, L, Abdel-Wahab, M, Holzhey, D, Kim, WK, Hamm, C, Buzzatti, N, Montorfano, M, Ludwig, S, Conradi, L, Seiffert, M, Guerrero, M, El Sabbagh, A, Rodés-Cabau, J, Guimaraes, L, Codner, P, Okuno, T, Pilgrim, T, Fiorina, C, Colombo, A, Mangieri, A, Eltchaninoff, H, Nombela-Franco, L, van Wiechen, Maarten, van Mieghem, Nicolas, Tchétché, D, Schoels, WH, Kullmer, M, Tamburino, C, Sinning, JM, Al-Kassou, B, Perlman, GY, Danenberg, H, Ielasi, A, Fraccaro, C, Tarantini, G, De Marco, F, Redwood, SR, Lisko, JC, Babaliaros, VC, Laine, M, Nerla, R, Castriota, F, Finkelstein, A, Loewenstein, I, Eitan, A, Jaffe, R, Ruile, P, Neumann, FJ, Piazza, N, Alosaimi, H, Sievert, H, Sievert, K, Russo, M, Andreas, M, Bunc, M, Latib, A, Godfrey, R, Hildick-Smith, D, Chuang, MYA, Blanke, P, Leipsic, J, Wood, DA, Nazif, T M, Kodali, S, Barbanti, M, Kornowski, R, Leon, MB, Webb, JG, Landes, U, Sathananthan, J, Witberg, G, de Backer, O, Sondergaard, L, Abdel-Wahab, M, Holzhey, D, Kim, WK, Hamm, C, Buzzatti, N, Montorfano, M, Ludwig, S, Conradi, L, Seiffert, M, Guerrero, M, El Sabbagh, A, Rodés-Cabau, J, Guimaraes, L, Codner, P, Okuno, T, Pilgrim, T, Fiorina, C, Colombo, A, Mangieri, A, Eltchaninoff, H, Nombela-Franco, L, van Wiechen, Maarten, van Mieghem, Nicolas, Tchétché, D, Schoels, WH, Kullmer, M, Tamburino, C, Sinning, JM, Al-Kassou, B, Perlman, GY, Danenberg, H, Ielasi, A, Fraccaro, C, Tarantini, G, De Marco, F, Redwood, SR, Lisko, JC, Babaliaros, VC, Laine, M, Nerla, R, Castriota, F, Finkelstein, A, Loewenstein, I, Eitan, A, Jaffe, R, Ruile, P, Neumann, FJ, Piazza, N, Alosaimi, H, Sievert, H, Sievert, K, Russo, M, Andreas, M, Bunc, M, Latib, A, Godfrey, R, Hildick-Smith, D, Chuang, MYA, Blanke, P, Leipsic, J, Wood, DA, Nazif, T M, Kodali, S, Barbanti, M, Kornowski, R, Leon, MB, and Webb, JG

Abstract

Background: Surgical aortic valve replacement and transcatheter aortic valve replacement (TAVR) are now both used to treat aortic stenosis in patients in whom life expectancy may exceed valve durability. The choice of initial bioprosthesis should therefore consider the relative safety and efficacy of potential subsequent interventions. Objectives: The aim of this study was to compare TAVR in failed transcatheter aortic valves (TAVs) versus surgical aortic valves (SAVs). Methods: Data were collected on 434 TAV-in-TAV and 624 TAV-in-SAV consecutive procedures performed at centers participating in the Redo-TAVR international registry. Propensity score matching was applied, and 330 matched (165:165) patients were analyzed. Principal endpoints were procedural success, procedural safety, and mortality at 30 days and 1 year. Results: For TAV-in-TAV versus TAV-in-SAV, procedural success was observed in 120 (72.7%) versus 103 (62.4%) patients (p = 0.045), driven by a numerically lower frequency of residual high valve gradient (p = 0.095), ectopic valve deployment (p = 0.081), coronary obstruction (p = 0.091), and conversion to open heart surgery (p = 0.082). Procedural safety was achieved in 116 (70.3%) versus 119 (72.1%) patients (p = 0.715). Mortality at 30 days was 5 (3%) after TAV-in-TAV and 7 (4.4%) after TAV-in-SAV (p = 0.570). At 1 year, mortality was 12 (11.9%) and 10 (10.2%), respectively (p = 0.633). Aortic valve area was larger (1.55 ± 0.5 cm2 vs. 1.37 ± 0.5 cm2; p = 0.040), and the mean residual gradient was lower (12.6 ± 5.2 mm Hg vs. 14.9 ± 5.2 mm Hg; p = 0.011) after TAV-in-TAV. The rate of moderate or greater residual aortic regurgitation was similar, but mild aortic regurgitation was more frequent after TAV-in-TAV (p = 0.003). Conclusions: In propensity score–matched cohorts of TAV-in-TAV versus TAV-in-SAV patients, TAV-in-TAV was associated with higher procedural success and similar procedural safety or mortality.

Published
2021

5. Hidradenite supurativa perianal como diagnóstico diferencial de doença inflamatória intestinal fistulizante

Author

Amanda Karolyne Batista Ferreira, Ana Carolina Cunha Leal, Julia Carmo Viela, Julia Martins Roriz, Marcella Gonçalves de Laia, Isabella Amorim Santos, Lídia Alberoni Neves de Assis, Emerson Abdulmassih Wood da Silva, Henrique Amorim Santos, Amanda Karolyne Batista Ferreira, Ana Carolina Cunha Leal, Julia Carmo Viela, Julia Martins Roriz, Marcella Gonçalves de Laia, Isabella Amorim Santos, Lídia Alberoni Neves de Assis, Emerson Abdulmassih Wood da Silva, and Henrique Amorim Santos

Abstract

A hidradenite supurativa perianal é uma doença inflamatória crônica de etiologia multifatorial que possui uma prevalência de 4%, acometendo principalmente indivíduos entre a segunda e terceira décadas de vida, além de ser mais frequente em mulheres. O acometimento de ductos das glândulas apócrinas causa lesões do tipo abscesso, nódulo, túneis ou cicatrizes. Foi discutida ainda a etiopatogenia da doença em questão e as estratégias de diagnóstico e tratamento específico. Este estudo de caso buscou evidenciar as manifestações clínicas da hidradenite supurativa e a construção do diagnóstico diferencial de doença inflamatória intestinal. Apresentamos o caso de um paciente com lesões pustulosas em região perianal há dois anos. Após exame clínico e biópsia, foi diagnosticado com quadro de hidradenite supurativa perianal, descartando a suspeita de doença inflamatória intestinal fistulizante. O paciente foi submetido a ressecção cirúrgica associada a sessões de câmara hiperbárica com cicatrização completa das lesões e bom prognóstico e melhora do paciente.

Published
2020

6. Hidradenite supurativa perianal como diagnóstico diferencial de doença inflamatória intestinal fistulizante

Author

Amanda Karolyne Batista Ferreira, Ana Carolina Cunha Leal, Julia Carmo Viela, Julia Martins Roriz, Marcella Gonçalves de Laia, Isabella Amorim Santos, Lídia Alberoni Neves de Assis, Emerson Abdulmassih Wood da Silva, Henrique Amorim Santos, Amanda Karolyne Batista Ferreira, Ana Carolina Cunha Leal, Julia Carmo Viela, Julia Martins Roriz, Marcella Gonçalves de Laia, Isabella Amorim Santos, Lídia Alberoni Neves de Assis, Emerson Abdulmassih Wood da Silva, and Henrique Amorim Santos

Abstract

A hidradenite supurativa perianal é uma doença inflamatória crônica de etiologia multifatorial que possui uma prevalência de 4%, acometendo principalmente indivíduos entre a segunda e terceira décadas de vida, além de ser mais frequente em mulheres. O acometimento de ductos das glândulas apócrinas causa lesões do tipo abscesso, nódulo, túneis ou cicatrizes. Foi discutida ainda a etiopatogenia da doença em questão e as estratégias de diagnóstico e tratamento específico. Este estudo de caso buscou evidenciar as manifestações clínicas da hidradenite supurativa e a construção do diagnóstico diferencial de doença inflamatória intestinal. Apresentamos o caso de um paciente com lesões pustulosas em região perianal há dois anos. Após exame clínico e biópsia, foi diagnosticado com quadro de hidradenite supurativa perianal, descartando a suspeita de doença inflamatória intestinal fistulizante. O paciente foi submetido a ressecção cirúrgica associada a sessões de câmara hiperbárica com cicatrização completa das lesões e bom prognóstico e melhora do paciente.

Published
2020

7. Hidradenite supurativa perianal como diagnóstico diferencial de doença inflamatória intestinal fistulizante

Author

Amanda Karolyne Batista Ferreira, Ana Carolina Cunha Leal, Julia Carmo Viela, Julia Martins Roriz, Marcella Gonçalves de Laia, Isabella Amorim Santos, Lídia Alberoni Neves de Assis, Emerson Abdulmassih Wood da Silva, Henrique Amorim Santos, Amanda Karolyne Batista Ferreira, Ana Carolina Cunha Leal, Julia Carmo Viela, Julia Martins Roriz, Marcella Gonçalves de Laia, Isabella Amorim Santos, Lídia Alberoni Neves de Assis, Emerson Abdulmassih Wood da Silva, and Henrique Amorim Santos

Abstract

A hidradenite supurativa perianal é uma doença inflamatória crônica de etiologia multifatorial que possui uma prevalência de 4%, acometendo principalmente indivíduos entre a segunda e terceira décadas de vida, além de ser mais frequente em mulheres. O acometimento de ductos das glândulas apócrinas causa lesões do tipo abscesso, nódulo, túneis ou cicatrizes. Foi discutida ainda a etiopatogenia da doença em questão e as estratégias de diagnóstico e tratamento específico. Este estudo de caso buscou evidenciar as manifestações clínicas da hidradenite supurativa e a construção do diagnóstico diferencial de doença inflamatória intestinal. Apresentamos o caso de um paciente com lesões pustulosas em região perianal há dois anos. Após exame clínico e biópsia, foi diagnosticado com quadro de hidradenite supurativa perianal, descartando a suspeita de doença inflamatória intestinal fistulizante. O paciente foi submetido a ressecção cirúrgica associada a sessões de câmara hiperbárica com cicatrização completa das lesões e bom prognóstico e melhora do paciente.

Published
2020

8. Hidradenite supurativa perianal como diagnóstico diferencial de doença inflamatória intestinal fistulizante

Author

Amanda Karolyne Batista Ferreira, Ana Carolina Cunha Leal, Julia Carmo Viela, Julia Martins Roriz, Marcella Gonçalves de Laia, Isabella Amorim Santos, Lídia Alberoni Neves de Assis, Emerson Abdulmassih Wood da Silva, Henrique Amorim Santos, Amanda Karolyne Batista Ferreira, Ana Carolina Cunha Leal, Julia Carmo Viela, Julia Martins Roriz, Marcella Gonçalves de Laia, Isabella Amorim Santos, Lídia Alberoni Neves de Assis, Emerson Abdulmassih Wood da Silva, and Henrique Amorim Santos

Abstract

A hidradenite supurativa perianal é uma doença inflamatória crônica de etiologia multifatorial que possui uma prevalência de 4%, acometendo principalmente indivíduos entre a segunda e terceira décadas de vida, além de ser mais frequente em mulheres. O acometimento de ductos das glândulas apócrinas causa lesões do tipo abscesso, nódulo, túneis ou cicatrizes. Foi discutida ainda a etiopatogenia da doença em questão e as estratégias de diagnóstico e tratamento específico. Este estudo de caso buscou evidenciar as manifestações clínicas da hidradenite supurativa e a construção do diagnóstico diferencial de doença inflamatória intestinal. Apresentamos o caso de um paciente com lesões pustulosas em região perianal há dois anos. Após exame clínico e biópsia, foi diagnosticado com quadro de hidradenite supurativa perianal, descartando a suspeita de doença inflamatória intestinal fistulizante. O paciente foi submetido a ressecção cirúrgica associada a sessões de câmara hiperbárica com cicatrização completa das lesões e bom prognóstico e melhora do paciente.

Published
2020

9. Timing of Staged Nonculprit Artery Revascularization in Patients With ST-Segment Elevation Myocardial Infarction: Complete Trial

Author

Wood, DA, Cairns, JA, Wang, J, Mehran, R, Storey, RF, Nguyen, H, Meeks, B, Kunadian, V, Tanguay, JF, Kim, HH, Cheema, A, Deghani, P, Natarajan, MK, Jolly, SS, Amerena, John, Keltai, M, James, S, Hlinomaz, O, Niemela, K, AlHabib, K, Lewis, BS, Nguyen, M, Sarma, J, Dzavik, V, Della Siega, A, Mehta, SR, Wood, DA, Cairns, JA, Wang, J, Mehran, R, Storey, RF, Nguyen, H, Meeks, B, Kunadian, V, Tanguay, JF, Kim, HH, Cheema, A, Deghani, P, Natarajan, MK, Jolly, SS, Amerena, John, Keltai, M, James, S, Hlinomaz, O, Niemela, K, AlHabib, K, Lewis, BS, Nguyen, M, Sarma, J, Dzavik, V, Della Siega, A, and Mehta, SR

Published
2019

10. Prognostic significance of anaemia in patients with heart failure with preserved and reduced ejection fraction: Results from the MAGGIC individual patient data meta-analysis

Author

Berry, C, Poppe, K, Gamble, G, Earle, N, Ezekowitz, J, Squire, I, Mcmurray, J, Mcalister, F, Komajda, M, Swedberg, K, Maggioni, A, Ahmed, A, Whalley, G, Doughty, R, Tarantini, L, Granger, C, Køber, L, Massie, B, Pocock, S, Somaratne, J, Andersson, B, Bayes-Genis, A, Cowie, M, Cubbon, R, Gonzalez-Juanatey, J, Gorini, M, Gotsman, I, Grigorian-Shamagian, L, Guazzi, M, Kearney, M, Di Lenarda, A, Lenzen, M, Lucci, D, Macín, S, Madsen, B, Martínez-Sellés, M, Oliva, F, Rich, M, Richards, M, Senni, M, Taffet, G, Tribouilloy, C, Troughton, R, Tsutsui, H, Ariti, C, Dobson, J, Hall, C, Lainchbury, J, Hogg, K, Norrie, J, Stevenson, K, Brett, M, Pfeffer, M, Held, P, Michelson, E, Olofsson, B, Östergren, J, Yusuf, S, Torp-Pedersen, C, Scholte op Reimer, W, Boersma, E, Vantrimpont, P, Follath, F, Cleland, J, Zwas, D, Planer, D, Azaz-Livshits, T, Admon, D, Lotan, C, Keren, A, Varela-Roman, A, Mazón-Ramos, P, Rigeiro-Veloso, P, Bandin-Dieguez, M, Myers, J, Arena, R, Armstrong, P, Cujec, B, Paterson, I, Wood, D, Coats, A, Thompson, S, Suresh, V, Poole-Wilson, P, Sutton, G, Robles, J, Prieto, L, Muñoa, M, Frades, E, Díaz-Castro, O, Almendral, J, Faggiano, P, Bertoli, D, Porcu, M, Opasich, C, Tavazzi, L, Kirk, V, Bay, M, Parner, J, Krogsgaard, K, Herzog, T, Boesgaard, S, Hassager, C, Nielsen, O, Aldershvile, J, Nielsen, H, Kober, L, Perna, E, Cimbaro Canella, J, Alvarenga, P, Pantich, R, Ríos, N, Farias, E, Badaracco, J, Hansen, J, Stokholm, K, Brons, J, Husum, D, Mortensen, L, Vazquez, R, Puig, T, Fernandez-Palomeque, C, Bardají, A, Pascual-Figal, D, Ordoñez-Llanos, J, Valdes, M, Gabarrus, A, Pavon, R, Pastor, L, Fiol, M, Nieto, V, Macaya, C, Cinca, J, Cygankiewitz, I, Bayes De Luna, A, Newton, J, Blackledge, H, Wright, S, Kerzner, R, Gage, B, Freedland, K, Huynh, B, Rovner, A, Carney, R, Teasdale, T, Bleyer, A, Kutka, N, Luchi, R, Rusinaru, D, Mahjoub, H, Soulière, V, Lévy, F, Peltier, M, Tsuchihashi, M, Takeshita, A, Maccarthy, P, Nolan, J, Lee, A, Prescott, R, Shah, A, Brooksby, W, Fox, K, Basante, P, Trillo, R, Garcia-Seara, J, Martinez-Sande, J, Gude, F, Berry C, Poppe KK, Gamble GD, Earle NJ, Ezekowitz JA, Squire IB, McMurray JJV, McAlister FA, Komajda M, Swedberg K, Maggioni AP, Ahmed A, Whalley GA, Doughty RN, Tarantini L, Granger C, Køber L, Massie B, Pocock S, Somaratne J, Andersson B, Bayes-Genis A, Cowie M, Cubbon R, Gonzalez-Juanatey J, Gorini M, Gotsman I, Grigorian-Shamagian L, Guazzi M, Kearney M, Di Lenarda A, Lenzen M, Lucci D, Macín S, Madsen B, Martínez-Sellés M, Oliva F, Rich M, Richards M, Senni M, Taffet G, Tribouilloy C, Troughton R, Tsutsui H, Ariti C, Dobson J, Hall C, Lainchbury J, Hogg K, Norrie J, Stevenson K, Brett M, Pfeffer MA, Held P, Michelson EL, Olofsson B, Östergren J, Yusuf S, Torp-Pedersen C, Scholte op Reimer W, Boersma E, Vantrimpont PJMJ, Follath F, Cleland J, Zwas D, Planer D, Azaz-Livshits T, Admon D, Lotan C, Keren A, Varela-Roman A, Mazón-Ramos P, Rigeiro-Veloso P, Bandin-Dieguez MA, Myers J, Arena R, Armstrong PW, Cujec B, Paterson I, Wood DA, Coats AJS, Thompson SG, Suresh V, Poole-Wilson PA, Sutton GC, Robles JAG, Prieto L, Muñoa MD, Frades E, Díaz-Castro O, Almendral J, Faggiano P, Bertoli D, Porcu M, Opasich C, Tavazzi L, Kirk V, Bay M, Parner J, Krogsgaard K, Herzog TM, Boesgaard S, Hassager C, Nielsen OW, Aldershvile J, Nielsen H, Kober L, Perna ER, Cimbaro Canella JP, Alvarenga P, Pantich R, Ríos N, Farias EF, Badaracco JR, Hansen JF, Stokholm KH, Brons J, Husum D, Mortensen LS, Vazquez R, Puig T, Fernandez-Palomeque C, Bardají A, Pascual-Figal D, Ordoñez-Llanos J, Valdes M, Gabarrus A, Pavon R, Pastor L, Fiol M, Nieto V, Macaya C, Cinca J, Cygankiewitz I, Bayes De Luna A, Newton JD, Blackledge HM, Wright SP, Kerzner R, Gage BF, Freedland KE, Huynh BC, Rovner A, Carney RM, Teasdale TA, Bleyer AJ, Kutka NJ, Luchi RJ, Rusinaru D, Mahjoub H, Soulière V, Lévy F, Peltier M, Tsuchihashi M, Takeshita A, MacCarthy PA, Nolan J, Lee AJ, Prescott RJ, Shah AM, Brooksby WP, Fox KAA, Basante P, Trillo R, Garcia-Seara J, Martinez-Sande JL, Gude F, Berry, C, Poppe, K, Gamble, G, Earle, N, Ezekowitz, J, Squire, I, Mcmurray, J, Mcalister, F, Komajda, M, Swedberg, K, Maggioni, A, Ahmed, A, Whalley, G, Doughty, R, Tarantini, L, Granger, C, Køber, L, Massie, B, Pocock, S, Somaratne, J, Andersson, B, Bayes-Genis, A, Cowie, M, Cubbon, R, Gonzalez-Juanatey, J, Gorini, M, Gotsman, I, Grigorian-Shamagian, L, Guazzi, M, Kearney, M, Di Lenarda, A, Lenzen, M, Lucci, D, Macín, S, Madsen, B, Martínez-Sellés, M, Oliva, F, Rich, M, Richards, M, Senni, M, Taffet, G, Tribouilloy, C, Troughton, R, Tsutsui, H, Ariti, C, Dobson, J, Hall, C, Lainchbury, J, Hogg, K, Norrie, J, Stevenson, K, Brett, M, Pfeffer, M, Held, P, Michelson, E, Olofsson, B, Östergren, J, Yusuf, S, Torp-Pedersen, C, Scholte op Reimer, W, Boersma, E, Vantrimpont, P, Follath, F, Cleland, J, Zwas, D, Planer, D, Azaz-Livshits, T, Admon, D, Lotan, C, Keren, A, Varela-Roman, A, Mazón-Ramos, P, Rigeiro-Veloso, P, Bandin-Dieguez, M, Myers, J, Arena, R, Armstrong, P, Cujec, B, Paterson, I, Wood, D, Coats, A, Thompson, S, Suresh, V, Poole-Wilson, P, Sutton, G, Robles, J, Prieto, L, Muñoa, M, Frades, E, Díaz-Castro, O, Almendral, J, Faggiano, P, Bertoli, D, Porcu, M, Opasich, C, Tavazzi, L, Kirk, V, Bay, M, Parner, J, Krogsgaard, K, Herzog, T, Boesgaard, S, Hassager, C, Nielsen, O, Aldershvile, J, Nielsen, H, Kober, L, Perna, E, Cimbaro Canella, J, Alvarenga, P, Pantich, R, Ríos, N, Farias, E, Badaracco, J, Hansen, J, Stokholm, K, Brons, J, Husum, D, Mortensen, L, Vazquez, R, Puig, T, Fernandez-Palomeque, C, Bardají, A, Pascual-Figal, D, Ordoñez-Llanos, J, Valdes, M, Gabarrus, A, Pavon, R, Pastor, L, Fiol, M, Nieto, V, Macaya, C, Cinca, J, Cygankiewitz, I, Bayes De Luna, A, Newton, J, Blackledge, H, Wright, S, Kerzner, R, Gage, B, Freedland, K, Huynh, B, Rovner, A, Carney, R, Teasdale, T, Bleyer, A, Kutka, N, Luchi, R, Rusinaru, D, Mahjoub, H, Soulière, V, Lévy, F, Peltier, M, Tsuchihashi, M, Takeshita, A, Maccarthy, P, Nolan, J, Lee, A, Prescott, R, Shah, A, Brooksby, W, Fox, K, Basante, P, Trillo, R, Garcia-Seara, J, Martinez-Sande, J, Gude, F, Berry C, Poppe KK, Gamble GD, Earle NJ, Ezekowitz JA, Squire IB, McMurray JJV, McAlister FA, Komajda M, Swedberg K, Maggioni AP, Ahmed A, Whalley GA, Doughty RN, Tarantini L, Granger C, Køber L, Massie B, Pocock S, Somaratne J, Andersson B, Bayes-Genis A, Cowie M, Cubbon R, Gonzalez-Juanatey J, Gorini M, Gotsman I, Grigorian-Shamagian L, Guazzi M, Kearney M, Di Lenarda A, Lenzen M, Lucci D, Macín S, Madsen B, Martínez-Sellés M, Oliva F, Rich M, Richards M, Senni M, Taffet G, Tribouilloy C, Troughton R, Tsutsui H, Ariti C, Dobson J, Hall C, Lainchbury J, Hogg K, Norrie J, Stevenson K, Brett M, Pfeffer MA, Held P, Michelson EL, Olofsson B, Östergren J, Yusuf S, Torp-Pedersen C, Scholte op Reimer W, Boersma E, Vantrimpont PJMJ, Follath F, Cleland J, Zwas D, Planer D, Azaz-Livshits T, Admon D, Lotan C, Keren A, Varela-Roman A, Mazón-Ramos P, Rigeiro-Veloso P, Bandin-Dieguez MA, Myers J, Arena R, Armstrong PW, Cujec B, Paterson I, Wood DA, Coats AJS, Thompson SG, Suresh V, Poole-Wilson PA, Sutton GC, Robles JAG, Prieto L, Muñoa MD, Frades E, Díaz-Castro O, Almendral J, Faggiano P, Bertoli D, Porcu M, Opasich C, Tavazzi L, Kirk V, Bay M, Parner J, Krogsgaard K, Herzog TM, Boesgaard S, Hassager C, Nielsen OW, Aldershvile J, Nielsen H, Kober L, Perna ER, Cimbaro Canella JP, Alvarenga P, Pantich R, Ríos N, Farias EF, Badaracco JR, Hansen JF, Stokholm KH, Brons J, Husum D, Mortensen LS, Vazquez R, Puig T, Fernandez-Palomeque C, Bardají A, Pascual-Figal D, Ordoñez-Llanos J, Valdes M, Gabarrus A, Pavon R, Pastor L, Fiol M, Nieto V, Macaya C, Cinca J, Cygankiewitz I, Bayes De Luna A, Newton JD, Blackledge HM, Wright SP, Kerzner R, Gage BF, Freedland KE, Huynh BC, Rovner A, Carney RM, Teasdale TA, Bleyer AJ, Kutka NJ, Luchi RJ, Rusinaru D, Mahjoub H, Soulière V, Lévy F, Peltier M, Tsuchihashi M, Takeshita A, MacCarthy PA, Nolan J, Lee AJ, Prescott RJ, Shah AM, Brooksby WP, Fox KAA, Basante P, Trillo R, Garcia-Seara J, Martinez-Sande JL, and Gude F

Abstract

Background: Anaemia is common among patients with heart failure (HF) and is an important prognostic marker. Aim: We sought to determine the prognostic importance of anaemia in a large multinational pooled dataset of prospectively enrolled HF patients, with the specific aim to determine the prognostic role of anaemia in HF with preserved and reduced ejection fraction (HF-PEF and HF-REF, respectively). Design: Individual person data meta-analysis. Methods: Patients with haemoglobin (Hb) data fromthe MAGGIC dataset were used. Anaemia was defined as Hb < 120 g/l in women and <130 g/l inmen. HF-PEF was defined as EF ≥ 50%; HF-REF was EF < 50%. Cox proportional hazardmodelling, with adjustment for clinically relevant variables, was undertaken to investigate factors associated with 3-year all-causemortality. Results: Thirteen thousand two hundred and ninety-five patients with HF from 19 studies (9887 with HF-REF and 3408 with HF-PEF). The prevalence of anaemia was similar among those with HF-REF and HF-PEF (42.8 and 41.6% respectively). Compared with patients with normal Hb values, those with anaemia were older, were more likely to have diabetes, ischaemic aetiology, New York Heart Association class IV symptoms, lower estimated glomerular filtration rate and were more likely to be taking diuretic and less likely to be taking a beta-blocker. Patients with anaemia had higher all-cause mortality (adjusted hazard ratio [aHR] 1.38, 95% confidence interval [CI] 1.25-1.51), independent of EF group: aHR 1.67 (1.39-1.99) in HFPEF and aHR 2.49 (2.13-2.90) in HF-REF. Conclusions: Anaemia is an adverse prognostic factor in HF irrespective of EF. The prognostic importance of anaemia was greatest in patients with HF-REF.

Published
2016

11. The survival of patients with heart failure with preserved or reduced left ventricular ejection fraction: an individual patient data meta-analysis

Author

Berry, C, Doughty, R, Granger, C, Kober, L, Massie, B, Mcalister, F, Mcmurray, J, Pocock, S, Poppe, K, Swedberg, K, Somaratne, J, Whalley, G, Ahmed, A, Andersson, B, Bayes-Genis, A, Cowie, M, Cubbon, R, Ezekowitz, J, Gonzalez-Juanatey, J, Gorini, M, Gotsman, I, Grigorian-Shamagian, L, Guazzi, M, Kearney, M, Komajda, M, di Lenarda, A, Lenzen, M, Lucci, D, Macin, S, Madsen, B, Maggioni, A, Martinez-Selles, M, Oliva, F, Rich, M, Richards, M, Senni, M, Squire, I, Taffet, G, Tarantini, L, Tribouilloy, C, Troughton, R, Tsutsui, H, Earle, N, Perera, K, Dobson, J, Hall, C, Richards, A, Lainchbury, J, Hogg, K, Norrie, J, Stevenson, K, Brett, M, Pfeffer, M, Held, P, Michelson, E, Olofsson, B, Ostergren, J, Yusuf, S, Torp-Pedersen, C, Reimer, W, Boersma, E, Vantrimpont, P, Follath, F, Cleland, J, Zwas, D, Planer, D, Azaz-Livshits, T, Admon, D, Lotan, C, Keren, A, Varela-Roman, A, Mazon-Ramos, P, Rigeiro-Veloso, P, Bandin-Dieguez, M, Myers, J, Arena, R, Armstrong, P, Cujec, B, Paterson, I, Wood, D, Coats, A, Thompson, S, Suresh, V, Poole-Wilson, P, Sutton, G, Robles, J, Prieto, L, Munoa, M, Frades, E, Diaz-Castro, O, Almendral, J, Faggiano, P, Bertoli, D, Porcu, M, Opasich, C, Tavazzi, L, Kirk, V, Bay, M, Parner, J, Krogsgaard, K, Herzog, T, Boesgaard, S, Hassager, C, Nielsen, O, Aldershvile, J, Nielsen, H, Perna, E, Canella, J, Alvarenga, P, Pantich, R, Rios, N, Farias, E, Badaracco, J, Hansen, J, Stokholm, K, Brons, J, Husum, D, Mortensen, L, Vazquez, R, Puig, T, Fernandez-Palomeque, C, Bardaji, A, Pascual-Figal, D, Ordonez-Llanos, J, Valdes, M, Gabarrus, A, Pavon, R, Pastor, L, Fiol, M, Nieto, V, Macaya, C, Cinca, J, de Luna, A, Newton, J, Blackledge, H, Wright, S, Kerzner, R, Gage, B, Freedland, K, Huynh, B, Rovner, A, Carney, R, Teasdale, T, Bleyer, A, Kutka, N, Luchi, R, Rusinaru, D, Mahjoub, H, Souliere, V, Levy, F, Peltier, M, Tsuchihashi, M, Takeshita, A, Maccarthy, P, Nolan, J, Lee, A, Prescott, R, Shah, A, Brooksby, W, Fox, K, Basante, P, Trillo, R, Garcia-Seara, J, Martinez-Sande, J, Gude, F, Berry C, Doughty RN, Granger C, Kober L, Massie B, McAlister F, McMurray J, Pocock S, Poppe K, Swedberg K, Somaratne J, Whalley GA, Ahmed A, Andersson B, Bayes-Genis A, Cowie M, Cubbon R, Ezekowitz J, Gonzalez-Juanatey J, Gorini M, Gotsman I, Grigorian-Shamagian L, Guazzi M, Kearney M, Komajda M, di Lenarda A, Lenzen M, Lucci D, Macin S, Madsen B, Maggioni A, Martinez-Selles M, Oliva F, Rich M, Richards M, Senni M, Squire I, Taffet G, Tarantini L, Tribouilloy C, Troughton R, Tsutsui H, Earle N, Perera K, Dobson J, Whalley G, Hall C, Richards AM, Lainchbury J, Hogg K, Norrie J, Stevenson K, Brett M, Pfeffer MA, Granger CB, Held P, McMurray JJV, Michelson EL, Olofsson B, Ostergren J, Yusuf S, Torp-Pedersen C, Lenzen MJ, Reimer WJMS, Boersma E, Vantrimpont PJMJ, Follath F, Cleland J, Zwas D, Planer D, Azaz-Livshits T, Admon D, Lotan C, Keren A, Varela-Roman A, Mazon-Ramos P, Rigeiro-Veloso P, Bandin-Dieguez MA, Gonzalez-Juanatey JR, Myers J, Arena R, McAlister FA, Armstrong PW, Cujec B, Paterson I, Cowie MR, Wood DA, Coats AJS, Thompson SG, Suresh V, Poole-Wilson PA, Sutton GC, Robles JAG, Prieto L, Munoa MD, Frades E, Diaz-Castro O, Almendral J, Faggiano P, Bertoli D, Porcu M, Opasich C, Tavazzi L, Maggioni AP, Kirk V, Bay M, Parner J, Krogsgaard K, Herzog TM, Boesgaard S, Hassager C, Nielsen OW, Aldershvile J, Nielsen H, Macin SM, Perna ER, Canella JPC, Alvarenga P, Pantich R, Rios N, Farias EF, Badaracco JR, Madsen BK, Hansen JF, Stokholm KH, Brons J, Husum D, Mortensen LS, Vazquez R, Puig T, Fernandez-Palomeque C, Bardaji A, Pascual-Figal D, Ordonez-Llanos J, Valdes M, Gabarrus A, Pavon R, Pastor L, Fiol M, Nieto V, Macaya C, Cinca J, de Luna AB, Newton JD, Blackledge HM, Squire IB, Wright SP, Kerzner R, Gage BF, Freedland KE, Rich MW, Huynh BC, Rovner A, Carney RM, Taffet GE, Teasdale TA, Bleyer AJ, Kutka NJ, Luchi RJ, Rusinaru D, Mahjoub H, Souliere V, Levy F, Peltier M, Tsuchihashi M, Takeshita A, MacCarthy PA, Kearney MT, Nolan J, Lee AJ, Prescott RJ, Shah AM, Brooksby WP, Fox KAA, Basante P, Trillo R, Garcia-Seara J, Martinez-Sande JL, Gude F, Berry, C, Doughty, R, Granger, C, Kober, L, Massie, B, Mcalister, F, Mcmurray, J, Pocock, S, Poppe, K, Swedberg, K, Somaratne, J, Whalley, G, Ahmed, A, Andersson, B, Bayes-Genis, A, Cowie, M, Cubbon, R, Ezekowitz, J, Gonzalez-Juanatey, J, Gorini, M, Gotsman, I, Grigorian-Shamagian, L, Guazzi, M, Kearney, M, Komajda, M, di Lenarda, A, Lenzen, M, Lucci, D, Macin, S, Madsen, B, Maggioni, A, Martinez-Selles, M, Oliva, F, Rich, M, Richards, M, Senni, M, Squire, I, Taffet, G, Tarantini, L, Tribouilloy, C, Troughton, R, Tsutsui, H, Earle, N, Perera, K, Dobson, J, Hall, C, Richards, A, Lainchbury, J, Hogg, K, Norrie, J, Stevenson, K, Brett, M, Pfeffer, M, Held, P, Michelson, E, Olofsson, B, Ostergren, J, Yusuf, S, Torp-Pedersen, C, Reimer, W, Boersma, E, Vantrimpont, P, Follath, F, Cleland, J, Zwas, D, Planer, D, Azaz-Livshits, T, Admon, D, Lotan, C, Keren, A, Varela-Roman, A, Mazon-Ramos, P, Rigeiro-Veloso, P, Bandin-Dieguez, M, Myers, J, Arena, R, Armstrong, P, Cujec, B, Paterson, I, Wood, D, Coats, A, Thompson, S, Suresh, V, Poole-Wilson, P, Sutton, G, Robles, J, Prieto, L, Munoa, M, Frades, E, Diaz-Castro, O, Almendral, J, Faggiano, P, Bertoli, D, Porcu, M, Opasich, C, Tavazzi, L, Kirk, V, Bay, M, Parner, J, Krogsgaard, K, Herzog, T, Boesgaard, S, Hassager, C, Nielsen, O, Aldershvile, J, Nielsen, H, Perna, E, Canella, J, Alvarenga, P, Pantich, R, Rios, N, Farias, E, Badaracco, J, Hansen, J, Stokholm, K, Brons, J, Husum, D, Mortensen, L, Vazquez, R, Puig, T, Fernandez-Palomeque, C, Bardaji, A, Pascual-Figal, D, Ordonez-Llanos, J, Valdes, M, Gabarrus, A, Pavon, R, Pastor, L, Fiol, M, Nieto, V, Macaya, C, Cinca, J, de Luna, A, Newton, J, Blackledge, H, Wright, S, Kerzner, R, Gage, B, Freedland, K, Huynh, B, Rovner, A, Carney, R, Teasdale, T, Bleyer, A, Kutka, N, Luchi, R, Rusinaru, D, Mahjoub, H, Souliere, V, Levy, F, Peltier, M, Tsuchihashi, M, Takeshita, A, Maccarthy, P, Nolan, J, Lee, A, Prescott, R, Shah, A, Brooksby, W, Fox, K, Basante, P, Trillo, R, Garcia-Seara, J, Martinez-Sande, J, Gude, F, Berry C, Doughty RN, Granger C, Kober L, Massie B, McAlister F, McMurray J, Pocock S, Poppe K, Swedberg K, Somaratne J, Whalley GA, Ahmed A, Andersson B, Bayes-Genis A, Cowie M, Cubbon R, Ezekowitz J, Gonzalez-Juanatey J, Gorini M, Gotsman I, Grigorian-Shamagian L, Guazzi M, Kearney M, Komajda M, di Lenarda A, Lenzen M, Lucci D, Macin S, Madsen B, Maggioni A, Martinez-Selles M, Oliva F, Rich M, Richards M, Senni M, Squire I, Taffet G, Tarantini L, Tribouilloy C, Troughton R, Tsutsui H, Earle N, Perera K, Dobson J, Whalley G, Hall C, Richards AM, Lainchbury J, Hogg K, Norrie J, Stevenson K, Brett M, Pfeffer MA, Granger CB, Held P, McMurray JJV, Michelson EL, Olofsson B, Ostergren J, Yusuf S, Torp-Pedersen C, Lenzen MJ, Reimer WJMS, Boersma E, Vantrimpont PJMJ, Follath F, Cleland J, Zwas D, Planer D, Azaz-Livshits T, Admon D, Lotan C, Keren A, Varela-Roman A, Mazon-Ramos P, Rigeiro-Veloso P, Bandin-Dieguez MA, Gonzalez-Juanatey JR, Myers J, Arena R, McAlister FA, Armstrong PW, Cujec B, Paterson I, Cowie MR, Wood DA, Coats AJS, Thompson SG, Suresh V, Poole-Wilson PA, Sutton GC, Robles JAG, Prieto L, Munoa MD, Frades E, Diaz-Castro O, Almendral J, Faggiano P, Bertoli D, Porcu M, Opasich C, Tavazzi L, Maggioni AP, Kirk V, Bay M, Parner J, Krogsgaard K, Herzog TM, Boesgaard S, Hassager C, Nielsen OW, Aldershvile J, Nielsen H, Macin SM, Perna ER, Canella JPC, Alvarenga P, Pantich R, Rios N, Farias EF, Badaracco JR, Madsen BK, Hansen JF, Stokholm KH, Brons J, Husum D, Mortensen LS, Vazquez R, Puig T, Fernandez-Palomeque C, Bardaji A, Pascual-Figal D, Ordonez-Llanos J, Valdes M, Gabarrus A, Pavon R, Pastor L, Fiol M, Nieto V, Macaya C, Cinca J, de Luna AB, Newton JD, Blackledge HM, Squire IB, Wright SP, Kerzner R, Gage BF, Freedland KE, Rich MW, Huynh BC, Rovner A, Carney RM, Taffet GE, Teasdale TA, Bleyer AJ, Kutka NJ, Luchi RJ, Rusinaru D, Mahjoub H, Souliere V, Levy F, Peltier M, Tsuchihashi M, Takeshita A, MacCarthy PA, Kearney MT, Nolan J, Lee AJ, Prescott RJ, Shah AM, Brooksby WP, Fox KAA, Basante P, Trillo R, Garcia-Seara J, Martinez-Sande JL, and Gude F

Abstract

Aims: A substantial proportion of patients with heart failure have preserved left ventricular ejection fraction (HF-PEF). Previous studies have reportedmixed resultswhether survival is similar to those patientswith heart failure and reduced EF (HF-REF). Methods and results: We compared survival in patients with HF-PEF with that in patients with HF-REF in a meta-analysis using individual patient data. Preserved EF was defined as an EF ≥ 50%. The 31 studies included 41 972 patients: 10 347 with HF-PEF and 31 625 with HF-REF. Compared with patients with HF-REF, those with HF-PEF were older (mean age 71 vs. 66 years), were more often women (50 vs. 28%), and have a history of hypertension (51 vs. 41%). Ischaemic aetiology was less common (43 vs. 59%) in patients with HF-PEF. There were 121 [95% confidence interval (CI): 117, 126] deaths per 1000 patient-years in those with HF-PEF and 141 (95% CI: 138, 144) deaths per 1000 patient-years in those with HF-REF. Patients with HF-PEF had lower mortality than those with HF-REF (adjusted for age, gender, aetiology, and history of hypertension, diabetes, and atrial fibrillation); hazard ratio 0.68 (95% CI: 0.64, 0.71). The risk of death did not increase notably until EF fell below 40%. Conclusion: Patients with HF-PEF have a lower risk of death than patients with HF-REF, and this difference is seen regardless of age, gender, and aetiology of HF. However, absolute mortality is still high in patients with HF-PEF highlighting the need for a treatment to improve prognosis.

Published
2012

Catalog

Books, media, physical & digital resources
See catalog results