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20 results on '"van Woensel, Job B. M."'

1. Barriers and perceived benefits of early mobilisation programmes in Dutch paediatric intensive care units

Author

Geven, Barbara M., Maaskant, Jolanda M., van Woensel, Job B. M., Verbruggen, Sascha C. A. T., Ista, Erwin, Geven, Barbara M., Maaskant, Jolanda M., van Woensel, Job B. M., Verbruggen, Sascha C. A. T., and Ista, Erwin

Abstract

Background: Early mobilisation of critically ill adults has been proven effective and is safe and feasible for critically ill children. However, barriers and perceived benefits of paediatric intensive care unit (PICU) staff involvement in mobilising critically ill children are largely unknown. Aim: To explore the barriers and perceived benefits regarding early mobilisation of critically ill children as perceived by PICU staff. Study design: A cross-sectional survey study among staff from seven PICUs in the Netherlands has been carried out. Results: Two hundred and fifteen of the 641 health care professionals (33.5%) who were invited to complete a questionnaire responded, of whom 159 (75%) were nurses, 40 (19%) physicians, and 14 (6%) physical therapists. Respondents considered early mobilisation potentially beneficial to shorten the duration of mechanical ventilation (86%), improve wake/sleep rhythm (86%) and shorten the length of stay in the PICU (85%). However, staff were reluctant to mobilise patients on extracorporeal membrane oxygenation (ECMO) (63%), and patients with traumatic brain injury (49%). Perceived barriers to early mobilisation were hemodynamic instability (78%), risk of dislocation of lines/tubes (74%), and level of sedation (62%). In total, 40.3% of PICU nurses stated that physical therapists provided enough support in their PICU, but 84.6% of the physical therapists believed support was sufficient. Conclusion: Participating PICU staff considered early mobilisation as potentially beneficial in improving patient outcomes, although barriers were noted in certain patient groups. Relevance to clinical practice: We identified barriers to early mobilisation which should be addressed in implementation research projects in order to make early mobilisation in critically ill children work.

Published
2023

2. Hospital-to-home transitions for children with medical complexity: part 2-a core outcome set

Author

Revalidatie Medisch Kinderen, Haspels, Heleen N, de Lange, Annemieke A, Alsem, Mattijs W, Sandbergen, Bettina, Dulfer, Karolijn, de Hoog, Matthijs, Joosten, Koen F M, van Karnebeek, Clara D, van Woensel, Job B M, Maaskant, Jolanda M, Revalidatie Medisch Kinderen, Haspels, Heleen N, de Lange, Annemieke A, Alsem, Mattijs W, Sandbergen, Bettina, Dulfer, Karolijn, de Hoog, Matthijs, Joosten, Koen F M, van Karnebeek, Clara D, van Woensel, Job B M, and Maaskant, Jolanda M

Published
2023

3. Hospital-to-home transitions for children with medical complexity: part 1, a systematic review of reported outcomes

Author

Revalidatie Medisch Kinderen, de Lange, Annemieke, Alsem, Mattijs W, Haspels, Heleen N, van Karnebeek, Clara D M, van Woensel, Job B M, Etten-Jamaludin, Faridi S, Maaskant, Jolanda M, Revalidatie Medisch Kinderen, de Lange, Annemieke, Alsem, Mattijs W, Haspels, Heleen N, van Karnebeek, Clara D M, van Woensel, Job B M, Etten-Jamaludin, Faridi S, and Maaskant, Jolanda M

Published
2023

4. Viral, bacterial, metabolic, and autoimmune causes of severe acute encephalopathy in sub-Saharan Africa: a multicenter cohort study

Author

Genetica Sectie Metabole Diagnostiek, Brain, Child Health, Cancer, Edridge, Arthur, Namazi, Ruth, Tebulo, Andrew, Mfizi, Anan, Deijs, Martin, Koekkoek, Sylvie, de Wever, Bob, van der Ende, Arie, Umiwana, Jeanine, de Jong, Menno D, Jans, Judith, Verhoeven-Duif, Nanda, Titulaer, Maarten, van Karnebeek, Clara, Seydel, Karl, Taylor, Terrie, Asiimwe-Kateera, Brenda, van der Hoek, Lia, Kabayiza, Jean-Claude, Mallewa, Macpherson, Idro, Richard, Boele van Hensbroek, Michael, van Woensel, Job B M, Genetica Sectie Metabole Diagnostiek, Brain, Child Health, Cancer, Edridge, Arthur, Namazi, Ruth, Tebulo, Andrew, Mfizi, Anan, Deijs, Martin, Koekkoek, Sylvie, de Wever, Bob, van der Ende, Arie, Umiwana, Jeanine, de Jong, Menno D, Jans, Judith, Verhoeven-Duif, Nanda, Titulaer, Maarten, van Karnebeek, Clara, Seydel, Karl, Taylor, Terrie, Asiimwe-Kateera, Brenda, van der Hoek, Lia, Kabayiza, Jean-Claude, Mallewa, Macpherson, Idro, Richard, Boele van Hensbroek, Michael, and van Woensel, Job B M

Published
2023

5. The Association between Weather Conditions and Admissions to the Paediatric Intensive Care Unit for Respiratory Syncytial Virus Bronchiolitis

Author

Infectieziekten onderzoek1 (Bont), CTI Bont, Child Health, Infection & Immunity, Linssen, Rosalie S, den Hollander, Bibiche, Bont, Louis, van Woensel, Job B M, Bem, Reinout A, On Behalf Of The Pice Study Group, Infectieziekten onderzoek1 (Bont), CTI Bont, Child Health, Infection & Immunity, Linssen, Rosalie S, den Hollander, Bibiche, Bont, Louis, van Woensel, Job B M, Bem, Reinout A, and On Behalf Of The Pice Study Group

Published
2021

6. Factors Associated with Mortality in Low-Risk Pediatric Critical Care Patients in the Netherlands

Author

Verlaat, Carin W., Visser, Idse H., Wubben, Nina, Hazelzet, Jan A., Lemson, Joris, van Waardenburg, Dick A, Van Der Heide, Douwe, Van Dam, Nicolette A., Jansen, Nicolaas J., Van Heerde, Mark, van der Starre, Cynthia, Van Asperen, Roelie, Kneyber, Martin, van Woensel, Job B M, Van Den Boogaard, Mark, van der Hoeven, Johannes G., Verlaat, Carin W., Visser, Idse H., Wubben, Nina, Hazelzet, Jan A., Lemson, Joris, van Waardenburg, Dick A, Van Der Heide, Douwe, Van Dam, Nicolette A., Jansen, Nicolaas J., Van Heerde, Mark, van der Starre, Cynthia, Van Asperen, Roelie, Kneyber, Martin, van Woensel, Job B M, Van Den Boogaard, Mark, and van der Hoeven, Johannes G.

Published
2017

7. Factors Associated with Mortality in Low-Risk Pediatric Critical Care Patients in the Netherlands

Author

Verlaat, Carin W., Visser, Idse H., Wubben, Nina, Hazelzet, Jan A., Lemson, Joris, van Waardenburg, Dick A, Van Der Heide, Douwe, Van Dam, Nicolette A., Jansen, Nicolaas J., Van Heerde, Mark, van der Starre, Cynthia, Van Asperen, Roelie, Kneyber, Martin, van Woensel, Job B M, Van Den Boogaard, Mark, van der Hoeven, Johannes G., Verlaat, Carin W., Visser, Idse H., Wubben, Nina, Hazelzet, Jan A., Lemson, Joris, van Waardenburg, Dick A, Van Der Heide, Douwe, Van Dam, Nicolette A., Jansen, Nicolaas J., Van Heerde, Mark, van der Starre, Cynthia, Van Asperen, Roelie, Kneyber, Martin, van Woensel, Job B M, Van Den Boogaard, Mark, and van der Hoeven, Johannes G.

Published
2017

8. Factors Associated with Mortality in Low-Risk Pediatric Critical Care Patients in the Netherlands

Author

Verlaat, Carin W., Visser, Idse H., Wubben, Nina, Hazelzet, Jan A., Lemson, Joris, van Waardenburg, Dick A, Van Der Heide, Douwe, Van Dam, Nicolette A., Jansen, Nicolaas J., Van Heerde, Mark, van der Starre, Cynthia, Van Asperen, Roelie, Kneyber, Martin, van Woensel, Job B M, Van Den Boogaard, Mark, van der Hoeven, Johannes G., Verlaat, Carin W., Visser, Idse H., Wubben, Nina, Hazelzet, Jan A., Lemson, Joris, van Waardenburg, Dick A, Van Der Heide, Douwe, Van Dam, Nicolette A., Jansen, Nicolaas J., Van Heerde, Mark, van der Starre, Cynthia, Van Asperen, Roelie, Kneyber, Martin, van Woensel, Job B M, Van Den Boogaard, Mark, and van der Hoeven, Johannes G.

Published
2017

9. Factors Associated with Mortality in Low-Risk Pediatric Critical Care Patients in the Netherlands

Author

UMC Utrecht, Intensive care patientenzorg, Child Health, Genetica Klinische Genetica, Verlaat, Carin W., Visser, Idse H., Wubben, Nina, Hazelzet, Jan A., Lemson, Joris, van Waardenburg, Dick A, Van Der Heide, Douwe, Van Dam, Nicolette A., Jansen, Nicolaas J., Van Heerde, Mark, van der Starre, Cynthia, Van Asperen, Roelie, Kneyber, Martin, van Woensel, Job B M, Van Den Boogaard, Mark, van der Hoeven, Johannes G., UMC Utrecht, Intensive care patientenzorg, Child Health, Genetica Klinische Genetica, Verlaat, Carin W., Visser, Idse H., Wubben, Nina, Hazelzet, Jan A., Lemson, Joris, van Waardenburg, Dick A, Van Der Heide, Douwe, Van Dam, Nicolette A., Jansen, Nicolaas J., Van Heerde, Mark, van der Starre, Cynthia, Van Asperen, Roelie, Kneyber, Martin, van Woensel, Job B M, Van Den Boogaard, Mark, and van der Hoeven, Johannes G.

Published
2017

10. Age-Dependent Changes in the Pulmonary Renin-Angiotensin System Are Associated With Severity of Lung Injury in a Model of Acute Lung Injury in Rats

Author

Schouten, Laura R A, Helmerhorst, Hendrik J F, Wagenaar, Gerry T M, Haltenhof, Tom, Lutter, René, Roelofs, Joris J T H, van Woensel, Job B M, van Kaam, Anton H L C, Bos, Albert P, Schultz, Marcus J, Walther, Thomas, Wösten-van Asperen, Roelie M, Schouten, Laura R A, Helmerhorst, Hendrik J F, Wagenaar, Gerry T M, Haltenhof, Tom, Lutter, René, Roelofs, Joris J T H, van Woensel, Job B M, van Kaam, Anton H L C, Bos, Albert P, Schultz, Marcus J, Walther, Thomas, and Wösten-van Asperen, Roelie M

Published
2016

12. Age-Dependent Changes in the Pulmonary Renin-Angiotensin System Are Associated With Severity of Lung Injury in a Model of Acute Lung Injury in Rats

Author

Schouten, Laura R A, Helmerhorst, Hendrik J F, Wagenaar, Gerry T M, Haltenhof, Tom, Lutter, René, Roelofs, Joris J T H, van Woensel, Job B M, van Kaam, Anton H L C, Bos, Albert P, Schultz, Marcus J, Walther, Thomas, Wösten-van Asperen, Roelie M, Schouten, Laura R A, Helmerhorst, Hendrik J F, Wagenaar, Gerry T M, Haltenhof, Tom, Lutter, René, Roelofs, Joris J T H, van Woensel, Job B M, van Kaam, Anton H L C, Bos, Albert P, Schultz, Marcus J, Walther, Thomas, and Wösten-van Asperen, Roelie M

Published
2016

14. Age-Dependent Changes in the Pulmonary Renin-Angiotensin System Are Associated With Severity of Lung Injury in a Model of Acute Lung Injury in Rats

Author

Schouten, Laura R A, Helmerhorst, Hendrik J F, Wagenaar, Gerry T M, Haltenhof, Tom, Lutter, René, Roelofs, Joris J T H, van Woensel, Job B M, van Kaam, Anton H L C, Bos, Albert P, Schultz, Marcus J, Walther, Thomas, Wösten-van Asperen, Roelie M, Schouten, Laura R A, Helmerhorst, Hendrik J F, Wagenaar, Gerry T M, Haltenhof, Tom, Lutter, René, Roelofs, Joris J T H, van Woensel, Job B M, van Kaam, Anton H L C, Bos, Albert P, Schultz, Marcus J, Walther, Thomas, and Wösten-van Asperen, Roelie M

Published
2016

15. Age-Dependent Changes in the Pulmonary Renin-Angiotensin System Are Associated With Severity of Lung Injury in a Model of Acute Lung Injury in Rats

Author

Schouten, Laura R A, Helmerhorst, Hendrik J F, Wagenaar, Gerry T M, Haltenhof, Tom, Lutter, René, Roelofs, Joris J T H, van Woensel, Job B M, van Kaam, Anton H L C, Bos, Albert P, Schultz, Marcus J, Walther, Thomas, Wösten-van Asperen, Roelie M, Schouten, Laura R A, Helmerhorst, Hendrik J F, Wagenaar, Gerry T M, Haltenhof, Tom, Lutter, René, Roelofs, Joris J T H, van Woensel, Job B M, van Kaam, Anton H L C, Bos, Albert P, Schultz, Marcus J, Walther, Thomas, and Wösten-van Asperen, Roelie M

Published
2016

18. Age-Dependent Changes in the Pulmonary Renin-Angiotensin System Are Associated With Severity of Lung Injury in a Model of Acute Lung Injury in Rats

Author

Intensive care patientenzorg, Schouten, Laura R A, Helmerhorst, Hendrik J F, Wagenaar, Gerry T M, Haltenhof, Tom, Lutter, René, Roelofs, Joris J T H, van Woensel, Job B M, van Kaam, Anton H L C, Bos, Albert P, Schultz, Marcus J, Walther, Thomas, Wösten-van Asperen, Roelie M, Intensive care patientenzorg, Schouten, Laura R A, Helmerhorst, Hendrik J F, Wagenaar, Gerry T M, Haltenhof, Tom, Lutter, René, Roelofs, Joris J T H, van Woensel, Job B M, van Kaam, Anton H L C, Bos, Albert P, Schultz, Marcus J, Walther, Thomas, and Wösten-van Asperen, Roelie M

Published
2016

19. Dexamethasone in children mechanically ventilated for lower Respiratory tract infection caused by respiratory syncytial Virus: a randomised controlled trial.

Author

Van Woensel, Job B. M., Vyas, Harish, Biarent, Dominique, Van Woensel, Job B. M., Vyas, Harish, and Biarent, Dominique

Abstract

Objective:To determine the efficacy of dexamethasone in the treatment of mechanically ventilated children with respiratory syncytial virus–severe lower respiratory tract infection.Design:International, multicenter, randomized, double-blind, placebo-controlled trial.Setting:Twelve pediatric intensive care units.Subjects:Children (<2 yrs) mechanically ventilated for respiratory syncytial virus lower respiratory tract infection. Children were prestratified for severity of oxygen abnormalities on admission.Intervention:Intravenous dexamethasone (0.6 mg/kg/day, 48 hrs) or placebo.Measurements and Main Results:A superiority approach was used in the subgroup of patients with mild oxygen abnormalities (arterial partial pressure of oxygen/fractional inspired oxygen concentration [PaO 2 /Fio 2 ] >200 mm Hg and/or mean arterial pressure ≤10 cm H 2 O) and a noninferiority approach in those with severe oxygen abnormalities (PaO 2 /Fio 2 ≤200 mm Hg and mean arterial pressure >10 cm H 2 O). Primary outcome was the duration of mechanical ventilation. In the subgroup with mild oxygenation abnormalities, 45 of the 89 included patients received dexamethasone and 44 placebo; in the subgroup with severe oxygenation abnormalities, 28 of the 56 included patients received dexamethasone and 28 placebo. Baseline characteristics in both treatment arms were similar for both subgroups. After the third interim analysis, the trial was stopped early for futility taking the slow enrollment into account. At that time, the median duration (interquartile range) of mechanical ventilation was 137 (91–195) hrs in the dexamethasone- and 139 (117–188) hrs in the placebo-treated patients in the subgroup with mild oxygenation abnormalities ( p = .6). In the subgroup with severe oxygenation abnormalities, it was 171 (136–212) hrs in the dexamethasone- and 170 (125–201) hrs in the placebo-treated patients ( p = .6).Conclusion:In this prematurely ended trial in children mechanically ventilated for severe respir, 0, info:eu-repo/semantics/published

Published
2011

20. Dexamethasone in children mechanically ventilated for lower Respiratory tract infection caused by respiratory syncytial Virus: a randomised controlled trial.

Author

Van Woensel, Job B. M., Vyas, Harish, Biarent, Dominique, Van Woensel, Job B. M., Vyas, Harish, and Biarent, Dominique

Abstract

Objective:To determine the efficacy of dexamethasone in the treatment of mechanically ventilated children with respiratory syncytial virus–severe lower respiratory tract infection.Design:International, multicenter, randomized, double-blind, placebo-controlled trial.Setting:Twelve pediatric intensive care units.Subjects:Children (<2 yrs) mechanically ventilated for respiratory syncytial virus lower respiratory tract infection. Children were prestratified for severity of oxygen abnormalities on admission.Intervention:Intravenous dexamethasone (0.6 mg/kg/day, 48 hrs) or placebo.Measurements and Main Results:A superiority approach was used in the subgroup of patients with mild oxygen abnormalities (arterial partial pressure of oxygen/fractional inspired oxygen concentration [PaO 2 /Fio 2 ] >200 mm Hg and/or mean arterial pressure ≤10 cm H 2 O) and a noninferiority approach in those with severe oxygen abnormalities (PaO 2 /Fio 2 ≤200 mm Hg and mean arterial pressure >10 cm H 2 O). Primary outcome was the duration of mechanical ventilation. In the subgroup with mild oxygenation abnormalities, 45 of the 89 included patients received dexamethasone and 44 placebo; in the subgroup with severe oxygenation abnormalities, 28 of the 56 included patients received dexamethasone and 28 placebo. Baseline characteristics in both treatment arms were similar for both subgroups. After the third interim analysis, the trial was stopped early for futility taking the slow enrollment into account. At that time, the median duration (interquartile range) of mechanical ventilation was 137 (91–195) hrs in the dexamethasone- and 139 (117–188) hrs in the placebo-treated patients in the subgroup with mild oxygenation abnormalities ( p = .6). In the subgroup with severe oxygenation abnormalities, it was 171 (136–212) hrs in the dexamethasone- and 170 (125–201) hrs in the placebo-treated patients ( p = .6).Conclusion:In this prematurely ended trial in children mechanically ventilated for severe respir, 0, info:eu-repo/semantics/published

Published
2011

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