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Your search keyword '"van de Ven, Steffi E."' showing total 9 results
Start Over Author "van de Ven, Steffi E." Publication Type Electronic Resources
9 results on '"van de Ven, Steffi E."'

1. Extending treatment criteria for Barrett's neoplasia: results of a nationwide cohort of 138 endoscopic submucosal dissection procedures

Author

van Munster, Sanne N, van Munster, Sanne N, Verheij, Eva P D, Nieuwenhuis, Esther A, Offerhaus, Johan G J A, Meijer, Sybren L, Brosens, Lodewijk A A, Weusten, Bas L A M, Alkhalaf, Alaa, Schenk, Ed B E, Schoon, Erik J, Curvers, Wouter L, van Tilburg, Laurelle, van de Ven, Steffi E M, Tang, Thjon J, Nagengast, Wouter B, Houben, Martin H M G, Seldenrijk, Kees C A, Bergman, Jacques J G H M, Koch, Arjun D, Pouw, Roos E, Dutch Barrett Expert Centers, van Munster, Sanne N, van Munster, Sanne N, Verheij, Eva P D, Nieuwenhuis, Esther A, Offerhaus, Johan G J A, Meijer, Sybren L, Brosens, Lodewijk A A, Weusten, Bas L A M, Alkhalaf, Alaa, Schenk, Ed B E, Schoon, Erik J, Curvers, Wouter L, van Tilburg, Laurelle, van de Ven, Steffi E M, Tang, Thjon J, Nagengast, Wouter B, Houben, Martin H M G, Seldenrijk, Kees C A, Bergman, Jacques J G H M, Koch, Arjun D, Pouw, Roos E, and Dutch Barrett Expert Centers

Abstract

BACKGROUND: The use of endoscopic submucosal dissection (ESD) is gradually expanding for treatment of neoplasia in Barrett's esophagus (BE). We aimed to report outcomes of all ESDs for BE neoplasia performed in the Netherlands.METHODS: Retrospective assessment of outcomes, using treatment and follow-up data from a joint database.RESULTS: 130/138 patients had complete ESDs, with 126/130 (97 %) en bloc resections. Median (interquartile range (IQR)) procedure time was 121 minutes (90-180). Pathology findings were high grade dysplasia (HGD) (5 %) or esophageal adenocarcinoma (EAC) T1a (43 %) or T1b (52 %; 19 % sm1, 33 % ≥ sm2). Among resections of HGD or T1a EAC lesions, 87 % (95 %CI 75 %-92 %) were both en bloc and R0; the corresponding value for T1b EAC lesions was 49 % (36 %-60 %). Among R1 resections, 10/34 (29 %) showed residual cancer, all detected at first endoscopic follow-up. The remaining 24 patients (71 %) showed no residual neoplasia. Six of these patients underwent surgery with no residual tumor; the remaining 18 underwent endoscopic follow-up during median 31 months with 1 local recurrence (annual recurrence rate 2 %). Among R0 resections, annual local recurrence rate during median 27 months was 0.5 %.CONCLUSION: In expert hands, ESD allows safe removal of bulky intraluminal neoplasia and submucosal cancer. ESD of the latter showed R1 resection margins in 50 %, yet only one third had persisting neoplasia at follow-up. To better stratify R1 patients with an indication for additional surgery, repeat endoscopy after healing of the ESD might be a helpful possible prognostic factor for residual cancer.

Published
2022

2. Screening for head and neck tumors in patients with esophageal squamous cell carcinoma and vice versa:a nationwide survey among medical specialists

Author

van Tilburg, Laurelle, van den Ban, Sophie A., van de Ven, Steffi E. M., Sewnaik, Aniel, Bruno, Marco J., Spaander, Manon C. W., de Jong, Robert J. Baatenburg, Koch, Arjun D., van Tilburg, Laurelle, van den Ban, Sophie A., van de Ven, Steffi E. M., Sewnaik, Aniel, Bruno, Marco J., Spaander, Manon C. W., de Jong, Robert J. Baatenburg, and Koch, Arjun D.

Abstract

Background and study aims Retrospectively, minimally 5% of patients with esophageal squamous cell carcinoma (ESCC) and 11 % with head and neck squamous cell carcinoma (HNSCC) in Western countries developed a second primary tumor (SPT). SPT screening in ESCC and HNSCC patients is not implemented routinely in daily practice in many Western countries. This study aimed to assess medical specialist knowledge and opinions regarding screening for head and neck SPTs (HNSPTs) in ESCC patients and vice versa in the Netherlands.Methods A nationwide survey among gastroenterologists and head and neck (HN) surgeons was conducted between December 2020 and March 2021. The survey consisted of 27 questions and focused on knowledge of medical specialists of the prevalence and opinions toward implementing screening for HNSPTs in ESCC patients and vice versa.Results One hundred twenty-eight gastroenterologists (20.5%) and 31 HN surgeons (50.0%) completed the survey. The expected median prevalence of HNSPTs in ESCC was 7.0% (interquartile range [IQR]: 5.0-15.0) among gastroenterologists and 5.0% (IQR:3.0-8.0) among HN surgeons. For ESPTs in HNSCC, the expected median prevalence was 9.5% (IQR: 5.0-12.0) among gastroenterologists and 4.0% (IQR: 2.0-5.0) among HN surgeons. Screening for HNSPTs and ESPTs was considered promising by 35.2% and 39.6%, respectively, which increased to 54.7% of the specialists after providing incidence data on SPTs. Of the HN surgeons, 41.3% felt they were as capable as gastroenterologists of performing esophageal screening.Conclusions This Dutch nationwide survey revealed a lack of knowledge and different perspectives among specialists about screening to detect SPTs in ESCC and HNSCC patients. Adequate education seems essential to increase awareness among specialists and improve SPT detection, independent of the need for implementation of screening for SPTs in ESCC and HNSCC patients.

Published
2022

3. Extending treatment criteria for Barrett's neoplasia: results of a nationwide cohort of 138 endoscopic submucosal dissection procedures

Author

van Munster, Sanne N, Verheij, Eva P D, Nieuwenhuis, Esther A, Offerhaus, Johan G J A, Meijer, Sybren L, Brosens, Lodewijk A A, Weusten, Bas L A M, Alkhalaf, Alaa, Schenk, Ed B E, Schoon, Erik J, Curvers, Wouter L, van Tilburg, Laurelle, van de Ven, Steffi E M, Tang, Thjon J, Nagengast, Wouter B, Houben, Martin H M G, Seldenrijk, Kees C A, Bergman, Jacques J G H M, Koch, Arjun D, Pouw, Roos E, Dutch Barrett Expert Centers, van Munster, Sanne N, Verheij, Eva P D, Nieuwenhuis, Esther A, Offerhaus, Johan G J A, Meijer, Sybren L, Brosens, Lodewijk A A, Weusten, Bas L A M, Alkhalaf, Alaa, Schenk, Ed B E, Schoon, Erik J, Curvers, Wouter L, van Tilburg, Laurelle, van de Ven, Steffi E M, Tang, Thjon J, Nagengast, Wouter B, Houben, Martin H M G, Seldenrijk, Kees C A, Bergman, Jacques J G H M, Koch, Arjun D, Pouw, Roos E, and Dutch Barrett Expert Centers

Abstract

BACKGROUND: The use of endoscopic submucosal dissection (ESD) is gradually expanding for treatment of neoplasia in Barrett's esophagus (BE). We aimed to report outcomes of all ESDs for BE neoplasia performed in the Netherlands.METHODS: Retrospective assessment of outcomes, using treatment and follow-up data from a joint database.RESULTS: 130/138 patients had complete ESDs, with 126/130 (97 %) en bloc resections. Median (interquartile range (IQR)) procedure time was 121 minutes (90-180). Pathology findings were high grade dysplasia (HGD) (5 %) or esophageal adenocarcinoma (EAC) T1a (43 %) or T1b (52 %; 19 % sm1, 33 % ≥ sm2). Among resections of HGD or T1a EAC lesions, 87 % (95 %CI 75 %-92 %) were both en bloc and R0; the corresponding value for T1b EAC lesions was 49 % (36 %-60 %). Among R1 resections, 10/34 (29 %) showed residual cancer, all detected at first endoscopic follow-up. The remaining 24 patients (71 %) showed no residual neoplasia. Six of these patients underwent surgery with no residual tumor; the remaining 18 underwent endoscopic follow-up during median 31 months with 1 local recurrence (annual recurrence rate 2 %). Among R0 resections, annual local recurrence rate during median 27 months was 0.5 %.CONCLUSION: In expert hands, ESD allows safe removal of bulky intraluminal neoplasia and submucosal cancer. ESD of the latter showed R1 resection margins in 50 %, yet only one third had persisting neoplasia at follow-up. To better stratify R1 patients with an indication for additional surgery, repeat endoscopy after healing of the ESD might be a helpful possible prognostic factor for residual cancer.

Published
2022

4. Incidence and outcomes of poor healing and poor squamous regeneration after radiofrequency ablation therapy for early Barrett's neoplasia

Author

MS MDL 1, Cancer, van Munster, Sanne N, Frederiks, Charlotte N, Nieuwenhuis, Esther A, Alvarez Herrero, Lorenza, Bogte, Auke, Alkhalaf, Alaa, Schenk, Boudewijn E, Schoon, Erik J, Curvers, Wouter L, Koch, Arjun D, van de Ven, Steffi E M, de Jonge, Pieter J F, Tang, Thjon J, Nagengast, Wouter B, Peters, Frans T M, Westerhof, Jessie, Houben, Martin H M G, Bergman, Jacques J G H M, Pouw, Roos E, Weusten, Bas L A M, MS MDL 1, Cancer, van Munster, Sanne N, Frederiks, Charlotte N, Nieuwenhuis, Esther A, Alvarez Herrero, Lorenza, Bogte, Auke, Alkhalaf, Alaa, Schenk, Boudewijn E, Schoon, Erik J, Curvers, Wouter L, Koch, Arjun D, van de Ven, Steffi E M, de Jonge, Pieter J F, Tang, Thjon J, Nagengast, Wouter B, Peters, Frans T M, Westerhof, Jessie, Houben, Martin H M G, Bergman, Jacques J G H M, Pouw, Roos E, and Weusten, Bas L A M

Published
2022

5. ID: 3520201 POOR HEALING AND POOR SQUAMOUS REGENERATION AFTER RADIOFREQUENCY ABLATION THERAPY FOR EARLY BARRETT'S NEOPLASIA: INCIDENCE, RISK FACTORS AND OUTCOMES

Author

MS MDL 1, Cancer, MS CGO, Van Munster, Sanne, Frederiks, Charlotte, Herrero, L. Alvarez, Bogte, Auke, Alkhalaf, A., Schenk, B. E., Schoon, Erik. J., Curvers, Wouter, Koch, Arjun D., Van De Ven, Steffi E., De Jonge, P. J. F., Tang, Thjon J., Nagengast, Wouter B., Peters, Frans, Westerhof, Jessie, Houben, Martin H., Bergman, Jacques, Pouw, Roos E., Weusten, Bas L., MS MDL 1, Cancer, MS CGO, Van Munster, Sanne, Frederiks, Charlotte, Herrero, L. Alvarez, Bogte, Auke, Alkhalaf, A., Schenk, B. E., Schoon, Erik. J., Curvers, Wouter, Koch, Arjun D., Van De Ven, Steffi E., De Jonge, P. J. F., Tang, Thjon J., Nagengast, Wouter B., Peters, Frans, Westerhof, Jessie, Houben, Martin H., Bergman, Jacques, Pouw, Roos E., and Weusten, Bas L.

Published
2021

6. Lymphovascular invasion quantification could improve risk prediction of lymph node metastases in patients with submucosal (T1b) esophageal adenocarcinoma

Author

MS MDL 1, Cancer, Pathologie Pathologen staf, MS CGO, van de Ven, Steffi E M, Suzuki, Lucia, Gotink, Annieke W, Ten Kate, Fiebo J C, Nieboer, Daan, Weusten, Bas L A M, Brosens, Lodewijk A A, van Hillegersberg, Richard, Alvarez Herrero, Lorenza, Seldenrijk, Cees A, Alkhalaf, Alaa, Moll, Freek C P, Curvers, Wouter, van Lijnschoten, Ineke G, Tang, Thjon J, van der Valk, Hans, Nagengast, Wouter B, Kats-Ugurlu, Gursah, Plukker, John T M, Houben, Martin H M G, van der Laan, Jaap S, Pouw, Roos E, Bergman, Jacques J G H M, Meijer, Sybren L, van Berge Henegouwen, Mark I, Wijnhoven, Bas P L, de Jonge, Pieter J F, Doukas, Michael, Bruno, Marco J, Biermann, Katharina, Koch, Arjun D, MS MDL 1, Cancer, Pathologie Pathologen staf, MS CGO, van de Ven, Steffi E M, Suzuki, Lucia, Gotink, Annieke W, Ten Kate, Fiebo J C, Nieboer, Daan, Weusten, Bas L A M, Brosens, Lodewijk A A, van Hillegersberg, Richard, Alvarez Herrero, Lorenza, Seldenrijk, Cees A, Alkhalaf, Alaa, Moll, Freek C P, Curvers, Wouter, van Lijnschoten, Ineke G, Tang, Thjon J, van der Valk, Hans, Nagengast, Wouter B, Kats-Ugurlu, Gursah, Plukker, John T M, Houben, Martin H M G, van der Laan, Jaap S, Pouw, Roos E, Bergman, Jacques J G H M, Meijer, Sybren L, van Berge Henegouwen, Mark I, Wijnhoven, Bas P L, de Jonge, Pieter J F, Doukas, Michael, Bruno, Marco J, Biermann, Katharina, and Koch, Arjun D

Published
2021

7. ENDOSCOPIC SUBMUCOSAL DISSECTION FOR BARRETT'S RELATED NEOPLASIA IN THE NETHERLANDS: RESULTS OF A NATIONWIDE COHORT OF 130 CASES

Author

Pathologie Pathologen staf, Cancer, MS MDL 1, Verheij, Eva P., Van Munster, Sanne N., Nieuwenhuis, Esther, van Tilburg, Laurelle, Offerhaus, Johan, Meijer, Sybren L., Brosens, Lodewijk A., Weusten, Bas L., Alkhalaf, A., Schenk, B. E., Schoon, Erik. J., Curvers, Wouter, Van De Ven, Steffi E., Nagengast, Wouter B., Houben, Martin H., Bergman, Jacques, Koch, Arjun D., Pouw, Roos E., Pathologie Pathologen staf, Cancer, MS MDL 1, Verheij, Eva P., Van Munster, Sanne N., Nieuwenhuis, Esther, van Tilburg, Laurelle, Offerhaus, Johan, Meijer, Sybren L., Brosens, Lodewijk A., Weusten, Bas L., Alkhalaf, A., Schenk, B. E., Schoon, Erik. J., Curvers, Wouter, Van De Ven, Steffi E., Nagengast, Wouter B., Houben, Martin H., Bergman, Jacques, Koch, Arjun D., and Pouw, Roos E.

Published
2021

8. RECURRENT NEOPLASIA AFTER ENDOSCOPIC TREATMENT FOR BARRETT'S NEOPLASIA IS RARE AND RANDOM BIOPSIES DO NOT CONTRIBUTE TO ITS DETECTION: RESULTS FROM A NATIONWIDE COHORT INCLUDING ALL 1,154 PATIENTS TREATED IN THE NETHERLANDS BETWEEN 2008 AND 2018.

Author

MS MDL 1, Cancer, MS CGO, van Munster, Sanne N., Nieuwenhuis, Esther, Weusten, Bas L., Herrero, L. Alvarez, Bogte, Auke, Alkhalaf, A., Schenk, B. E., Schoon, Erik. J., Curvers, Wouter, Koch, Arjun D., van de Ven, Steffi E., de Jonge, P. J. F., Tang, Thjon J., Nagengast, Wouter B., Peters, Frans, Westerhof, Jessie, Houben, Martin H., Bergman, Jacques, Pouw, Roos E., MS MDL 1, Cancer, MS CGO, van Munster, Sanne N., Nieuwenhuis, Esther, Weusten, Bas L., Herrero, L. Alvarez, Bogte, Auke, Alkhalaf, A., Schenk, B. E., Schoon, Erik. J., Curvers, Wouter, Koch, Arjun D., van de Ven, Steffi E., de Jonge, P. J. F., Tang, Thjon J., Nagengast, Wouter B., Peters, Frans, Westerhof, Jessie, Houben, Martin H., Bergman, Jacques, and Pouw, Roos E.

Published
2020

9. LONG-TERM OUTCOMES AFTER ENDOSCOPIC RESECTION WITHOUT SUBSEQUENT ABLATION THERAPY FOR EARLY BARRETT'S NEOPLASIA

Author

MS MDL 1, Cancer, MS CGO, van Munster, Sanne N., Nieuwenhuis, Esther, Weusten, Bas L., Herrero, L. Alvarez, Bogte, Auke, Alkhalaf, A., Schenk, B. E., Schoon, Erik. J., Curvers, Wouter, Koch, Arjun D., van de Ven, Steffi E., de Jonge, P. J. F., Tang, Thjon J., Nagengast, Wouter B., Peters, Frans, Westerhof, Jessie, Houben, Martin H., Bergman, Jacques, Pouw, Roos E., MS MDL 1, Cancer, MS CGO, van Munster, Sanne N., Nieuwenhuis, Esther, Weusten, Bas L., Herrero, L. Alvarez, Bogte, Auke, Alkhalaf, A., Schenk, B. E., Schoon, Erik. J., Curvers, Wouter, Koch, Arjun D., van de Ven, Steffi E., de Jonge, P. J. F., Tang, Thjon J., Nagengast, Wouter B., Peters, Frans, Westerhof, Jessie, Houben, Martin H., Bergman, Jacques, and Pouw, Roos E.

Published
2020

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