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1. A genome-wide association study follow-up suggests a possible role for PPARGin systemic sclerosis susceptibility

Author

L?pez-Isac, Elena, Bossini-Castillo, Lara, Simeon, Carmen, Egurbide, Mar?a, Alegre-Sancho, Juan, Callejas, Jose, Roman-Ivorra, Jos?, Freire, Mayka, Beretta, Lorenzo, Santaniello, Alessandro, Air?, Paolo, Lunardi, Claudio, Hunzelmann, Nicolas, Riemekasten, Gabriela, Witte, Torsten, Kreuter, Alexander, Distler, J?rg H, Schuerwegh, Annemie, Vonk, Madelon, Voskuyl, Alexandre, Shiels, Paul, van Laar, Jacob, Fonseca, Carmen, Denton, Christopher, Herrick, Ariane, Worthington, Jane, Assassi, Shervin, Koeleman, Bobby, Mayes, Maureen, Radstake, Timothy, and Martin, Javier

Abstract

A recent genome-wide association study (GWAS) comprising a French cohort of systemic sclerosis (SSc) reported several non-HLA single-nucleotide polymorphisms (SNPs) showing a nominal association in the discovery phase. We aimed to identify previously overlooked susceptibility variants by using a follow-up strategy.

Published
2014
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