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Objective:The International Classification of Functioning, Disability, and Health (ICF) is a comprehensive and universally accepted framework for describing functioning and disability in any health condition. The ICF includes more than 1,400 categories, and ICF Core Sets (ICF-CSs) for specific health conditions facilitate the tool’s use in the clinical setting. Using the ICF-CSs for schizophrenia, this study identifies the most relevant problems that social workers encounter when working with individuals who have schizophrenia and analyzes to what extent these problems are represented in the Core Sets. Method:Social workers experienced in working with persons who have schizophrenia were recruited for a three-round Delphi study. A total of 57 social workers from 20 countries completed the first round, and 36 completed all three rounds. Results:In the third round, consensus was reached for 93 ICF categories (92.5% of which are included in the Comprehensive ICF-CS for schizophrenia) and 20 personal factors. The most represented areas concerned mental functions; major life areas; attitudes; and services, systems, and policies. Conclusions:Results support the validity of the ICF-CSs for schizophrenia from the perspective of social workers.