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Byline: David Eggert Critics of electric vehicles are outspending EV proponents 7 to 1 on political advertising, with the messaging largely concentrated in Michigan, home to the U.S. auto industry. [...]

Byline: David Eggert Michigan insurers have sued the state after a ruling on 2019 changes to auto insurance, saying it means other parts of the law also cannot be retroactively [...]

Byline: David Eggert Democrat Elissa Slotkin raised quadruple what Republican Mike Rogers did over three months and quintupled his spending, but her advantage is being dampened by outside groups that [...]

Byline: David Eggert Republicans are pumping tens of millions of dollars into Michigan's open U.S. Senate race, bidding to catch up with Democrats in a contest that a political newsletter [...]

Byline: David Eggert Electric vehicles and the batteries that power them are the future in the U.S. auto industry's home state but for now serve as a flashpoint in the [...]

Byline: Dave Eggert Evette Griffie, 36 Vice President, Customer and Community Engagement DTE Energy Detroit native Evette Griffie knew she wanted to go into business when she went to the [...]

Byline: David Eggert Jen Flood, 37 Budget Director, State of Michigan Jen Flood first took an interest in public policy at Michigan State University, unsuccessfully working to defeat a 2006 [...]

Byline: David Eggert An independent review casts doubt on the ability of DTE Electric and Consumers Energy to substantially improve grid reliability before 2029, questioning their aggressive timelines and noting [...]

Byline: David Eggert A top Democratic lawmaker is staying mum about whether new minimum wage and paid sick time laws will be altered before they take effect while also saying [...]

Byline: David Eggert Tyler Rossmaessler, 39 Executive Director Flint and Genesee Economic Alliance Growing up in Fenton in the 1990s and 2000s, Tyler Rossmaessler watched with dismay the disinvestment in [...]

Byline: David Eggert Hassan Beydoun, 37 Group Executive of Economic Development and Counsel to the Mayor As a kid growing up in Detroit and Dearborn, Hassan Beydoun knew he wanted [...]

Byline: David Eggert The state of Michigan will proceed with implementing a minimum wage schedule that includes an initial jump to $12.48 an hour next year and $14.97 in 2028. [...]

Byline: Kurt Nagl and David Eggert Michigan officials are working to land a microchip project that could bring an up to $55 billion investment and 10,000 jobs to a Flint-area [...]

Byline: David Eggert Tim Boring's day job is leading the Michigan Department of Agriculture and Rural Development, which supports and regulates the industry and is responsible for food and animal [...]

Byline: David Eggert Emergency medical services providers are asking Michigan lawmakers to reimburse them more than $6 million after the state prison agency's former health care contractor did not pay [...]

Water reuse within a particular industrial facility is not a new idea. Power industry facilities operating in arid areas have been designed to be 'zero liquid discharge' (ZLD) for more [...]

Byline: David Eggert If a paid family and medical leave law is enacted in Michigan, it could cost employers and employees $1.3 billion to $1.6 billion a year initially and [...]

Byline: David Eggert Michigan businesses are bracing for sweeping changes to the state's paid sick time law, revisions they warn will be just as consequential -- potentially more so -- [...]

Byline: David Eggert Doug Roberts, a long-time leader in state government who served as Michigan treasurer during much of former Gov. John Engler's tenure and later led a Michigan State [...]

Byline: David Eggert The Michigan Economic Development Corp. on July 19 announced the creation of Michigan's Growth Office, which is tasked with working to implement population-growth strategies following a report [...]

Byline: David Eggert Rep. Angela Witwer helped to broker the next state budget, her second go-around shepherding the process as House budget chair. This time, the third-term Democrat and other [...]

Byline: David Eggert Michigan's economic development board on July 9 moved to rescind a $29 million tax break that was to help subsidize the $1 billion-plus transformation of an Upper [...]

Byline: David Eggert Michigan homeowners could install solar panels, clotheslines and make other energy-saving improvements regardless of bans set by homeowners associations under a law that will take effect in [...]

Byline: David Eggert Gov. Gretchen Whitmer wrote a book to 'put a little light out there in a damn dark time,' a period in which she has led Michigan through [...]

Byline: David Eggert DTE Energy Co. broke ground June 10 on a $460 million battery facility at the site of its former Trenton Channel coal-fired power plant, a 220-megawatt project [...]

Byline: David Eggert Backers of a plan to put a cap over Interstate 75 in downtown Detroit and make it a park that unites both sides don't have to go [...]

Byline: David Eggert A top agriculture official said June 12 the state has found no bird flu within the poultry industry in the last six weeks while dairy farms continue [...]

Byline: David Eggert The Democratic-controlled Michigan House voted May 22 to require charter schools to put the name of their authorizer and educational management organization on newly created or altered [...]

Byline: David Eggert Gov. Gretchen Whitmer and lawmakers are preparing for a politically thorny proposition should the Michigan Supreme Court invalidate the state's minimum wage law and reinstate one that [...]

Byline: Andy Balaskovitz, David Eggert, Anna Fifelski, Kurt Nagl and Nick Manes The 2024 Mackinac Policy Conference is in the books. The Detroit Regional Chamber's annual gathering of 1,500 business [...]

Byline: David Eggert The state, not schools, would issue work permits to Michigan minors under legislation that is dividing lawmakers and garnering initial opposition from the business community. The House [...]

Byline: David Eggert The Detroit Regional Chamber on May 22 canceled the bipartisan U.S. Senate candidates debate at the Mackinac Policy Conference after Republicans Mike Rogers and Justin Amash never [...]

Byline: David Eggert Gov. Gretchen Whitmer and her allies stood on the porch of the Grand Hotel at the state's preeminent business summit and outlined Make It in Michigan, a [...]

Byline: David Eggert Nearly 500 people are asking Gov. Gretchen Whitmer and Detroit Mayor Mike Duggan to pause the project to convert sunken Interstate 375 into a street-level boulevard, saying [...]

Byline: David Eggert How can Michigan attract more businesses and jobs? Those who work in the economic development field, and others, have ideas beyond alterations to the closing fund for [...]

Byline: David Eggert The Detroit Medical Center will continue getting property tax breaks valued at $16.7 million annually after the state unanimously approved a 15-year extension of its Renaissance Zone [...]

Byline: David Eggert About 1,500 people will trek north for the annual Mackinac Policy Conference this week, the state's preeminent business summit that this year will be centered around inspiring [...]

Byline: David Eggert Republicans are in the minority in the Michigan House for the first time in 14 years. Their leader, Rep. Matt Hall of Kalamazoo County's Richland Township, wants [...]

Byline: David Eggert Michigan is inching toward possibly addressing a major problem in how road and bridge repairs are paid for: the fact that a lot of funding comes from [...]

Byline: David Eggert Gov. Gretchen Whitmer is advocating for a 13-fold increase in a state fee to take waste to landfills in a bid to curb out-of-state trash and generate [...]

Byline: David Eggert New state budget director Jen Flood has 15 years of experience in Lansing, starting as an intern at the Michigan Economic Development Corp. and advancing to coordinate [...]

Byline: David Eggert DTE Electric is planning to offer rebates to support the installation of more than 19,000 electric vehicle chargers from 2025 through 2028, triple the number of rebates [...]

Byline: David Eggert Where did you grow up in Michigan, when did you leave and why did you move back? I grew up in La Salle, a tiny town in [...]

The article in Idaho Magazine recounts a photographer's experience at Pettit Lake, where he hoped to capture images of pronghorn but instead witnessed a sandhill crane courtship ritual. The photographer describes the mesmerizing dance of the crane pair, highlighting their lifelong bond and intricate mating behavior. The article provides insights into the breeding habits of sandhill cranes, emphasizing the unique opportunity the photographer had to witness and document this rare event in Idaho. [Extracted from the article]

Amyloid-β (Aβ) is thought to be neuronally derived in Alzheimer’s disease (AD). However, transcripts of amyloid precursor protein (APP) and amyloidogenic enzymes are equally abundant in oligodendrocytes (OLs). By cell-type-specific deletion of Bace1in a humanized knock-in AD model, APPNLGF, we demonstrate that OLs and neurons contribute to Aβ plaque burden. For rapid plaque seeding, excitatory projection neurons must provide a threshold level of Aβ. Ultimately, our findings are relevant for AD prevention and therapeutic strategies.

Purpose: Paranasal anomalies, frequently identified in routine radiological screenings, exhibit diverse morphological characteristics. Due to the diversity of anomalies, supervised learning methods require large labelled dataset exhibiting diverse anomaly morphology. Self-supervised learning (SSL) can be used to learn representations from unlabelled data. However, there are no SSL methods designed for the downstream task of classifying paranasal anomalies in the maxillary sinus (MS). Methods: Our approach uses a 3D convolutional autoencoder (CAE) trained in an unsupervised anomaly detection (UAD) framework. Initially, we train the 3D CAE to reduce reconstruction errors when reconstructing normal maxillary sinus (MS) image. Then, this CAE is applied to an unlabelled dataset to generate coarse anomaly locations by creating residual MS images. Following this, a 3D convolutional neural network (CNN) reconstructs these residual images, which forms our SSL task. Lastly, we fine-tune the encoder part of the 3D CNN on a labelled dataset of normal and anomalous MS images. Results: The proposed SSL technique exhibits superior performance compared to existing generic self-supervised methods, especially in scenarios with limited annotated data. When trained on just 10% of the annotated dataset, our method achieves an area under the precision-recall curve (AUPRC) of 0.79 for the downstream classification task. This performance surpasses other methods, with BYOL attaining an AUPRC of 0.75, SimSiam at 0.74, SimCLR at 0.73 and masked autoencoding using SparK at 0.75. Conclusion: A self-supervised learning approach that inherently focuses on localizing paranasal anomalies proves to be advantageous, particularly when the subsequent task involves differentiating normal from anomalous maxillary sinuses. Access our code at https://github.com/mtec-tuhh/self-supervised-paranasal-anomaly.

Byline: David Eggert Supporters of a state income tax cut that took effect this year filed a lawsuit Thursday to keep it intact in 2024. The Mackinac Center Legal Foundation [...]

Byline: David Eggert A recent Michigan Supreme Court ruling that overturned 22 years of precedent will have major implications within liability law, benefiting people who sue property owners -- typically [...]

Byline: David Eggert The Michigan State University board of trustees on Wednesday authorized the school to request liquor licenses to sell alcohol to the public at four football games in [...]

Byline: David Eggert Despite pushback from watchdog groups, Gov. Gretchen Whitmer and lawmakers have committed $150 million in state funding in an attempt to do the unprecedented: restart a nuclear [...]