Search

Your search keyword '"FORMINS"' showing total 17 results
Start Over Descriptor "FORMINS" Publication Type Magazines
17 results on '"FORMINS"'

1. University of Rome Researcher Adds New Data to Research in Medulloblastoma (Mdb-28. The Cytoskeleton Regulators Formins Control The Shh Pathway And Are Involved in Medulloblastoma Tumorigenesis).

Subjects
FORMINS, MEDULLOBLASTOMA, CYTOSKELETON, RESEARCH personnel, INTRACELLULAR space
Abstract

Researchers from the University of Rome have conducted a study on medulloblastoma, a lethal pediatric brain tumor. The study focused on the Sonic Hedgehog (SHH) molecular subgroup of medulloblastoma, which is characterized by alterations in the SHH development pathway. The researchers identified formins, which are involved in cytoskeletal dynamics, as regulators of SHH signaling and found that they can affect the growth and stiffness of SHH-dependent tumor cells. These findings provide insights into the role of the cytoskeleton in medulloblastoma and could potentially lead to the development of innovative interventions. [Extracted from the article]

Published
2024

2. Studies from Albany Medical College Update Current Data on Cancer (Nucleating Amoeboid Cancer Cell Motility With Diaphanous Related Formins).

Subjects
CANCER cell motility, FORMINS, MEDICAL schools, CELL motility
Abstract

A recent report from Albany Medical College discusses the role of phenotypic plasticity in determining the tissue invasive capacity of cancer cells. The transition from a mesenchymal to an amoeboid state has been found to facilitate the movement of cancer cells through confined environments. The report highlights the role of Diaphanous related formins (DRFs) in promoting or suppressing bleb formation, which is a characteristic of amoeboid migration. The researchers suggest that further investigation of DRFs in animal models may lead to potential therapeutic targets for cancer treatment. This research was supported by the American Cancer Society and has been peer-reviewed. [Extracted from the article]

Published
2024

4. Reports Outline Malaria Study Results from University of Melbourne (Plasmodium falciparum formins are essential for invasion and sexual stage development).

Subjects
PLASMODIUM falciparum, FORMINS, MALARIA, MOLECULAR biology, NEWSPAPER editors
Abstract

Keywords for this news article include: University of Melbourne, Malaria, Tropical Disease, Health and Medicine, Plasmodium falciparum, Mosquito-Borne Diseases. Keywords: Health and Medicine; Malaria; Mosquito-Borne Diseases; Plasmodium falciparum; Tropical Disease EN Health and Medicine Malaria Mosquito-Borne Diseases Plasmodium falciparum Tropical Disease 1249 1249 1 09/04/23 20230908 NES 230908 2023 SEP 8 (NewsRx) -- By a News Reporter-Staff News Editor at Zika & Mosquito Week -- Research findings on malaria are discussed in a new report. [Extracted from the article]

Published
2023

6. New Cell and Developmental Biology Study Findings Recently Were Reported by Researchers at Columbia University (FHODs: Nuclear tethered formins for nuclear mechanotransduction).

Subjects
DEVELOPMENTAL biology, CYTOLOGY, FORMINS, N-terminal residues, NUCLEAR proteins
Abstract

Keywords: Biology; Cell and Developmental Biology EN Biology Cell and Developmental Biology 642 642 1 05/22/23 20230526 NES 230526 2023 MAY 26 (NewsRx) -- By a News Reporter-Staff News Editor at Genomics & Genetics Weekly -- New research on cell and developmental biology is the subject of a new report. Keywords for this news article include: Columbia University, New York City, New York, United States, North and Central America, Cell and Developmental Biology. [Extracted from the article]

Published
2023

7. Findings in Cancer Reported from University of Freiburg (Vesicle-associated Actin Assembly By Formins Promotes Tgf Beta-induced Angptl4 Trafficking, Secretion and Cell Invasion).

Subjects
FORMINS, ACTIN, TRANSFORMING growth factors-beta, SECRETION
Abstract

Moreover, using super resolution microscopy, ANGPTL4 trafficking is actin-dependent with FMNL2 directly polymerizing actin at ANGPTL4-containing vesicles, which are associated with Rab8a and myosin Vb. Keywords: Freiburg; Germany; Europe; Cancer; Health and Medicine; Oncology EN Freiburg Germany Europe Cancer Health and Medicine Oncology 2023 MAR 7 (NewsRx) -- By a News Reporter-Staff News Editor at Cancer Weekly -- Current study results on Cancer have been published. The news reporters obtained a quote from the research from the University of Freiburg, "Here, Formin-like 2 (FMNL2) is identified to be necessary for ANGPTL4 trafficking and secretion in response to TGF beta. [Extracted from the article]

Published
2023

8. A GBD uncovered: the FHOD1 N terminus is formin'.

Author

Baarlink C and Grosse R

Subjects
Binding Sites physiology, Catalysis, Fetal Proteins metabolism, Formins, GTP Phosphohydrolases metabolism, Humans, Models, Biological, Models, Molecular, Nuclear Proteins metabolism, Phosphorylation, Protein Binding, Protein Structure, Tertiary physiology, rho-Associated Kinases metabolism, Fetal Proteins chemistry, Nuclear Proteins chemistry
Published
2008
Full Text
View/download PDF

9. A lock on formins.

Author

Xu W

Subjects
Carrier Proteins metabolism, Crystallography, X-Ray, Formins, Models, Molecular, Protein Structure, Tertiary, Carrier Proteins chemistry, rho GTP-Binding Proteins chemistry
Published
2006
Full Text
View/download PDF

10. Ubiquitylation in apoptosis: DIAP1's (N-)en(d)igma.

Author

Ditzel M and Meier P

Subjects
Animals, Baculoviridae metabolism, Carrier Proteins chemistry, Caspases metabolism, Drosophila, Formins, Humans, Models, Biological, Proteasome Endopeptidase Complex metabolism, Proteasome Endopeptidase Complex physiology, Protein Binding, Protein Structure, Tertiary, Ubiquitin chemistry, Ubiquitin metabolism, Apoptosis, Carrier Proteins physiology, Ubiquitin physiology
Published
2005
Full Text
View/download PDF

11. Progressing actin: Formin as a processive elongation machine.

Author

Kovar DR and Pollard TD

Subjects
Adenosine Triphosphate metabolism, Animals, Contractile Proteins metabolism, Formins, Humans, Hydrolysis, Microfilament Proteins metabolism, Models, Molecular, Profilins, Protein Structure, Tertiary physiology, Actin Cytoskeleton metabolism, Actins biosynthesis, Carrier Proteins metabolism, Fetal Proteins metabolism, Nuclear Proteins metabolism
Published
2004
Full Text
View/download PDF

12. Formin' adherens junctions.

Author

Zigmond S

Subjects
Actins metabolism, Cytoskeletal Proteins metabolism, Epithelial Cells ultrastructure, Formins, Microfilament Proteins, Protein Structure, Tertiary physiology, Trans-Activators metabolism, alpha Catenin, beta Catenin, Adherens Junctions physiology, Cadherins metabolism, Cell Adhesion physiology, Epithelial Cells physiology, Fetal Proteins metabolism, Nuclear Proteins metabolism
Published
2004
Full Text
View/download PDF

13. Formins initiate new actin filaments.

Author

Pollard TD

Subjects
Actin-Related Protein 2, Actin-Related Protein 3, Formins, Microfilament Proteins, Models, Biological, Saccharomyces cerevisiae metabolism, Saccharomyces cerevisiae Proteins metabolism, Actins metabolism, Cytoskeletal Proteins, Fetal Proteins metabolism, Nuclear Proteins metabolism
Published
2002
Full Text
View/download PDF

14. Hair hear!

Author

Phimister B

Subjects
Dyneins, Formins, GPI-Linked Proteins, Hair Cells, Auditory ultrastructure, Humans, Microscopy, Electron, Mutation, Myosin VIIa, Adaptor Proteins, Signal Transducing, Carrier Proteins genetics, Deafness genetics, Extracellular Matrix Proteins genetics, Hair Cells, Auditory physiology, Membrane Glycoproteins genetics, Myosins genetics
Published
1998
Full Text
View/download PDF

15. Two deaf mice, two deaf mice...

Author

Heller S and Hudspeth AJ

Subjects
Animals, Carrier Proteins genetics, Connexin 26, Connexins genetics, Dyneins, Extracellular Matrix Proteins genetics, Formins, GPI-Linked Proteins, Hair Cells, Auditory pathology, Homeodomain Proteins genetics, Humans, Membrane Glycoproteins genetics, Mice, Myosin VIIa, Myosins genetics, POU Domain Factors, Transcription Factor Brn-3C, Transcription Factors genetics, Adaptor Proteins, Signal Transducing, DNA-Binding Proteins, Deafness genetics, Hearing Loss, Sensorineural genetics, Mutation, Nerve Tissue Proteins
Published
1998
Full Text
View/download PDF

16. Deafness. Sounds from the cochlea.

Author

Avraham KB

Subjects
Actins metabolism, Carrier Proteins genetics, Carrier Proteins metabolism, Connexin 26, Connexins genetics, Connexins metabolism, Deafness congenital, Deafness epidemiology, Formins, Humans, Sulfate Transporters, Sulfates metabolism, Syndrome, Adaptor Proteins, Signal Transducing, Cochlea metabolism, Deafness genetics, Membrane Transport Proteins
Published
1997
Full Text
View/download PDF

17. The architecture of hearing.

Author

Pennisi E

Subjects
Animals, Carrier Proteins physiology, Chromosome Mapping, Cilia ultrastructure, Cochlea metabolism, Connexin 26, Deafness pathology, Dyneins, Female, Formins, Gap Junctions physiology, Gap Junctions ultrastructure, Genes, Recessive, Hair Cells, Auditory physiology, Hair Cells, Auditory ultrastructure, Humans, Male, Mice, Mice, Neurologic Mutants, Mutation, Myosin VIIa, Pedigree, Adaptor Proteins, Signal Transducing, Carrier Proteins genetics, Connexins genetics, Deafness genetics, Myosins genetics
Published
1997
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results