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Presents a study in the U.S. which states that muscle pressor reflex describes a potential role of vanilloid type I receptor and acid-sensing ion channel. Likelihood of reflex cardiovascular response to muscle contraction to be mediated by mechanical and metabolic stimulation of thin muscles afferent fibers; Uncertainty of metabolic stimulants and receptors involve in responses; Blocked of pressor component of the response by capsazepine.