Since the emergence of the Islamic Republic in Iran, social scientists, including international relations (IR) scholars, have been called to develop endogenous/indigenous theories to reflect Iranian/Islamic points of view. This theorizing has led some Iranian scholars to develop ideas about international life on the basis of Islamic texts and teachings. Furthermore, due to an increasing awareness of the Eurocentric nature of IR theories over the last few years, the international community of IR scholars has become open to non-Western IR theories. This opening has made homegrown theorizing more attractive to Iranian IR scholars, and debates about it have become more vivid. This article seeks to examine the attempts by the Iranian IR community to conceptualize and theorize IR from Iranian/Islamic points of view and to show how contextual factors have limited such attempts. The first part of the article reviews the IR scholarship in Iran to give a portrait of Iranians' achievements in this regard. The second part examines contextual factors that may have affected homegrown theorizing in Iran, including international agency, sources of inspiration, the dynamism of the IR community, the relationship between academia and government, and intellectual autonomy. An evaluation of this structural context suggests that even if theorizing IR from an Iranian point of view is both possible and preferable, this cannot be done unless certain structural constraints are overcome. Keywords: International Relations, Iran, homegrown theorizing, Iranian theory of IR, 1. Introduction Since the emergence of the Islamic Republic in Iran, social scientists, including IR scholars, have been called to develop theories to reflect Iranian/Islamic points of view. In the [...]