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MYH7variants cause hypertrophic cardiomyopathy (HCM), noncompaction cardiomyopathy (NCCM), and dilated cardiomyopathy (DCM). Screening of relatives of patients with genetic cardiomyopathy is recommended from 10 to 12 years of age onward, irrespective of the affected gene.

'IN THE YEAR TO COME PEOPLE WILL BE CONCERNED FIRST and foremost with survival.' So says Jon Lovell, head of sustainability at Drivers Jonas, who admits that environmental issues are [...]

BUILDINGS MAY PUMP OUT 45% OF THE UK'S carbon emissions, but the property industry is gradually waking up to sustainability. Property Week has compiled an inspirational list of Britain's top [...]

GOOD ASSET MANAGEMENT HAS COME BACK INTO fashion after the credit crunch sent property values tumbling by 10%, 15% or even 20% since last summer. Property owners can no longer [...]

THERE ARE JUST 60 DAYS TO GO BEFORE BUSINESS rates become payable on empty commercial property (see box). For landlords and occupiers who are stuck with empty buildings, the bill [...]

THIS MONTH, THE LAND REGISTRY WAS FORCED to remove sensitive documents from its website after a series of mortgage frauds; Erinaceous said it was suing its former head of valuation [...]

THESE ARE THE FIRST IMAGES OF HOW DERWENT London is planning to transform the Angel Centre in Islington, north London. The Angel Centre is the first building to be refurbished [...]

THE GOOD TIMES ARE ROLLING FOR OUR CLASS OF 2004--the group of 10 young surveyors first profiled by Property Week at the beginning of their careers as graduate trainees in [...]

THINK 07 OFFERED A MIX OF HOPE AND HORROR. The three-day conference on sustainable development heard former US vice-president AI Gore describe climate change as 'the biggest crisis we've ever [...]

THIS WEEK KING STURGE LAUNCHED MEASURES TO cut energy use and increase recycling across its 45 offices in the UK and Europe as part of a new policy on corporate [...]

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ZED HOMES IS PLANNING THE BIGGEST GREEN housing project yet seen in the UK--and possibly Europe. The developer--ZED stands for Zero Emissions Development--wants to build 1,000 flats and 80,000 sq [...]

ANDREW NICHOLSON, Cushman & Wakefield There have been so many takeovers recently and the gap between the large firms and smaller practices is widening. How do you see the future [...]

'SOMEBODY'S GOT TO GO THERE, I SUPPOSE,' shrugs the cab driver on the way to Heathrow, as I explain that I am heading for Albania. My visit to the poorest [...]

NEXT WEEK THE RICS WILL BEGIN TO CONSULT members on a package of reforms that could safeguard the very future of the Institution, according to its chief executive, Louis Armstrong. [...]

1 JOHN PRESCOTT John Prescott's place at our list's summit was never in doubt. He has irreversibly made his mark on the property industry. In planning, Prescott has used his [...]

Property's biggest bonuses proved the greatest attraction when the 2004 Macdonald & Company/RICS salary survey asked who you would most like to work for other than your current organisation. But [...]

ObjectiveLopinavir/ritonavir (LPV/RTV) exposure is decreased in children after crushing the tablets. Whether exposure is also decreased in adult patients is not known. This study evaluated the exposure of LPV/RTV in adult patients after administration of crushed LPV/RTV tablets.MethodsBlood samples were drawn from patients with COVID-19 who were receiving crushed LPV/RTV 400/100 mg tablets twice daily.ResultsPlasma concentrations for 11 patients with COVID-19 (eight men, mean age 62.6 years) were included. The measured plasma concentrations of LPV were substantially higher than reported for patients with HIV.ConclusionsThere is adequate exposure from crushed LPV/RTV tablets, but because of limited experience, therapeutic drug monitoring is still advised.

LEGAL & GENERAL: STREET PERFORMER Legal & General is revamping its retail property in Guildford in response to Westfield's extended and refurbished Friary Shopping Centre. Legal & General owns around [...]

THE STRIKING THING ABOUT CHRIS DE PURY IS HOW relaxed and unstuffy he is. Although only just 40, he is one of the most senior property lawyers in Britain, and [...]

THE PINNACLE IS SET TO BECOME ONE OF LONDON'S tallest and most prestigious buildings. Designed by Kohn Pedersen Fox, the tower will be 300 metres high and contain 950,000 sq [...]

THE BRITISH PROPERTY FEDERATION HAS THIS WEEK launched an accreditation scheme for landlords that lets tenants know they comply with the Leasing Business Premises Code. The Commercial Landlords Accreditation Scheme [...]

THIS SUMMER THE G0VERNMEN WILL GRAPPLE with the painful issue of childhood leukaemia and whether to ban development near overhead power lines. Concerns about whether the lines cause leukaemia in [...]

OFFICE OCCUPIERS ACROSS LONDON'S WEST END ARE FACING massive rent hikes that could force many to relocate. A slew of rent reviews fall clue this month in Mayfair, some of [...]

LAST WEEK THE CROWN ESTATE SUBMITTED a planning application to redevelop more than 1m sq ft of shops and offices at the lower end of Regent Street, in the heart [...]

DEADLY ASBESTOS STILL LURKS IN BETWEEN 500,000 and 1.5 million buildings in the UK, estimates the Health and Safety Executive. Asbestos is only dangerous when it is disturbed and the [...]

PLANNERS ARE QUITTING LOCAL AUTHORITIES in their droves for better-paid jobs with fast-growing private sector consultancies. Not only do these consultancies pay more, they offer more stimulating work, less bureaucracy [...]

OWNERS OF EMPTY COMMERCIAL PROPERTY ARE frantically searching for ways to avoid a massive hike in business rates announced by chancellor Gordon Brown last month. Since the 1980s owners of [...]

IF ANYONE WAS LEFT WITH ANY DOUBT THAT THE green agenda had arrived in the property industry it was surely dispelled last month when British Land announced plans to become [...]

A NEW VERSION OF THE COMMERCIAL LEASE CODE was launched this week in London. The great and the good were there, from housing and planning minister Yvette Cooper to the [...]

ANY DAY NOW THE GOVERNMENT IS EXPECTED TO publish a white paper that will herald one radical change to the planning system: the creation of an independent planning commission. It [...]

THE COST OF PROPERTY MANAGEMENT IS rising fast. The latest Oscar surveys of service charges published by Jones Lang LaSalle next week, show sharp rises in the running costs of [...]

IN LESS THAN 10 MONTHS, ANY LANDLORD THAT wants to sell or let commercial property of more than 10,764 sq ft (1,000 sq m) will need an energy performance certificate. [...]

NEXT WEEK A FIERCE BAFFLE WILL BEGIN BETWEEN Land Securities and conservationists over a proposed 39-storey skyscraper at 20 Fenchurch Street in the City of London. From 6 March, for [...]

WHEN WEMBLEY STADIUM FINALLY OPENS, football fans will be reassured to know that the venue will have been checked for terrorist bombs by highly trained sniffer dogs. One of those [...]

FRESH CONTROVERSY IS BREWING OVER developers' contributions to local amenities. Unilateral undertakings, a high-speed alternative to section 106 agreements with local councils, are becoming increasingly popular. Yet they have been [...]

A TIDAL WAVE OF INJURY CLAIMS IS BEARING down on landlords and their property managers. People are claiming compensation after slipping, tripping and stumbling in Britain's shopping centres, retail centres [...]

READING UNIVERSITY HAS BEEN THE TRAINING ground for thousands of people who work in property. Now the alumni association for property students hopes to raise 10m £ in donations to [...]

LOCAL COUNCILS ACROSS ENGLAND ARE CLOSING scores of outlying offices and moving thousands of staff into new or refurbished headquarters in a bid to slash long-term occupational costs. Private offices [...]

A CHARITY THAT PROVIDES CARE HOMES FOR THE elderly is being hit by demands for affordable housing. The Royal Masonic Benevolent Institution, which runs 18 care homes across England and [...]

EVEN THE MOST HARDENED atheist will admit that it takes guts to stand up and say you're a Christian, especially in the tough world of property. Yet a network called [...]

SUPERMARKETS COULD BE PREVENTED FROM opening too many outlets in a single area under radical proposals being considered by the Competition Commission. The planning system will be at the heart [...]

PROPERTY MANAGEMENT IS A LOW-MARGIN business and the pressure to reduce costs is seemingly neverending. In response, many firms are following the example of banks and insurance firms by moving [...]

DEVELOPERS IN EDINBURGH ARE BEING FORCED TO pay millions of pounds towards the cost of a new tram system that many believe will never be built. The developers do not [...]

A LARGE CROWD OF BIG HITTERS FROM THE construction and property industries gathered at the House of Commons last month to discuss the building programme for the 2012 Olympic Games. [...]

A GREEN REVOLUTION IS UNDER WAY IN THE capital. London mayor Ken Livingstone is forcing developers to build more energy-efficient buildings that release less carbon dioxide into the atmosphere. The [...]

WHEN GORDON INGRAM LEFT HIS JOB WITH surveyor Schatunowsld Brooks and set up his own rights-of-light consultancy in 1993, he took two big clients with him: British Land and Land [...]

'ALL OF US ARE WORRIED ABOUT HIGH HOUSING densities. We are all worried about creating the ghettoes of tomorrow.' So says Tony Collins, director at London-based planning consultant CGMS. Collins [...]

THE RICS HAS WON AN IMPORTANT VICTORY IN ITS long-running battle with the Treasury and the Financial Services Authority over the regulation of property managers and building surveyors. Within a [...]

Photographs by Dominik Gigler BRITAIN'S PLANNING SYSTEM IS BEING CONTROLLED by real-life Victor Meldrews who are old, out of touch and who hate change. The analogy may be extreme, but [...]