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1. Single nucleotide polymorphism of TAG-1 influences IVIg responsiveness of Japanese patients with CIDPSYMBOL

Author

Iijima, M, Tomita, M, Morozumi, S, Kawagashira, Y, Nakamura, T, Koike, H, Katsuno, M, Hattori, N, Tanaka, F, Yamamoto, M, and Sobue, G

Abstract

Chronic inflammatory demyelinating polyneuropathy (CIDP) is characterized by immune-mediated peripheral demyelination. Although corticosteroid, IV immunoglobulin (IVIg) and plasma exchange have been established as the most effective therapeutics, subpopulations of patients show little or no response to either of these therapies. In this study, we examined whether particular genetic factors influence the therapeutic responsiveness of patients with CIDP.

Published
2009
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