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2. Focal Nodular Hyperplasia of the Liver: Contrast‐Enhanced Ultrasonographic Features With Sonazoid

Author

Lee, Jongmee, Jeong, Woo Kyoung, Lim, Hyo K., and Kim, Ah Young

Abstract

To investigate ultrasonographic features of focal nodular hyperplasia of the liver with contrast‐enhanced ultrasonography (CEUS) using Sonazoid (perflubutane; GE Healthcare, Oslo, Norway). Thirty‐one patients with 31 focal nodular hyperplasia nodules who underwent CEUS using Sonazoid between July 2012 and February 2015 were included in this study. After the microbubble contrast agent was injected, intermittent CEUS images were obtained during the following 4 phases: arterial (10–40 seconds), portal venous (60–90 seconds), delayed (3 minutes), and Kupffer (>10 minutes). Three abdominal radiologists retrospectively reviewed the images and achieved consensus for vascular (central artery, stellate vascularity, and centrifugal enhancement) and dynamic enhancement patterns during the late arterial, portal venous, delayed, and Kupffer phases. The patients included 12 men and 19 women (age range, 21–82 years; mean, 47 years). The mean diameter of the lesions ± SD was 2.2 ± 0.9 cm (range, 1.0–4.0 cm). On CEUS, 24 of 31 lesions (77.4%) showed central artery and stellate vascularity in the early arterial phase, and 25 (80.6%) showed centrifugal enhancement. Twenty‐six lesions (83.9%) were hyperechoic during the late arterial phase and showed hyperenhancement or isoenhancement during the serial dynamic phases. Kupffer‐phase images indicated that only 2 lesions (6.5%) were hypoechoic compared with surrounding liver parenchyma, whereas 29 (93.5%) remained either hyperechoic (2 [6.5%]) or isoechoic (27 [87.1%]). Contrast‐enhanced US using Sonazoid for focal nodular hyperplasia showed typical vascular patterns of central artery vascularity, stellate vascularity, and centrifugal enhancement. Most cases were either hyperenhanced or isoenhanced on serial dynamic‐ and Kupffer‐phase imaging. Based on these results, CEUS can provide useful information for noninvasive focal nodular hyperplasia diagnoses.

Published
2018
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3. Low-dose CT for the diagnosis of appendicitis in adolescents and young adults (LOCAT): a pragmatic, multicentre, randomised controlled non-inferiority trial

Author

Kim, Hyuk Jung, Jeon, Byeong Geon, Hong, Chong Kun, Kwon, Kye Won, Han, Seung Bong, Paik, Soya, Jang, Suk Ki, Ha, Young Rock, Kim, Young Sik, Lee, Min Hee, Yi, Boem Ha, Shin, Eung Jin, Lee, Hae Kyung, Kim, Hee Kyung, Kim, Ho Jung, Choi, Jae Hyung, Cho, Young Soon, Kim, Min-Jeong, Kim, Dong Kyu, Choe, Ji-Young, Min, Kyueng-Whan, Lim, Man Sup, Ha, Sang Ook, Lim, Sang Woo, Sohn, Youdong, Lee, Young Hwan, Park, Ji Hoon, Gu, Bon Seung, Lee, Hye Seung, Lee, Jae Hyuk, Sim, Ji Ye, Kim, Joonghee, Lee, Kyoung Ho, Kim, Kyuseok, Ahn, Soyeon, Kang, Sung-Bum, Lee, Yoon Jin, Jo, You Hwan, Kim, Young Hoon, Ko, Yousun, Choi, Seung Joon, Song, Bohyung, Goh, Byung Ho, Lim, Chaesuk, Kim, Chang Rae, Seo, Cho Rong, Kim, Eunbaeck, Han, Gio, Woo, Jae-Hyug, Kim, Jinhyun, Min, Kyoungjin, Lee, Min-A, Jeong, Min Ju, Lee, Min Kyoung, Lim, Yong Su, Shim, Young Sup, Park, Sung Bin, Kim, Chan Woong, Lee, Dong Hoon, Lee, Seung Eun, Kim, Sung Eun, Choi, Yoo Shin, Rha, Sung Eun, Jung, Eun Sun, Na, Gun Hyung, Kim, Han Joon, Yoo, Han Mo, Chang, Hye Kyung, Choi, Joon Il, Park, Kyu Nam, Park, Michael Yong, Choi, Moon Hyung, Oh, Sang Hoon, Jung, Seung Eun, Lee, Sohee, Im, Soo Ah, Kim, Soo Hyun, Oh, Soon Nam, Hong, Tae Ho, Kang, Won-Kyung, Lee, Young Joon, Lee, Young Hwan, Kang, Dong Baek, Han, Hyun Soo, Choi, Jeong Woo, Yoon, Ki-Jung, Hwang, Yong, Hong, Seong Sook, Hwang, Eui Sung, Chung, Heajin, Jang, Hye Young, Hwang, Jiyoung, Park, Jun Bum, Hur, Kyung Yul, Jeen, Yoon Mi, Lee, Young Joo, Cho, Young Shin, Cho, Han Jin, Choi, Inyoung, Park, Jong Hak, Kim, Jooyeong, Yeom, Suk Keu, Moon, Sung Woo, Kim, Young Sik, Kim, Mi Sung, Shin, Dong Hyuk, Kwon, Heon-Ju, Choi, Pil Cho, Han, Sang Kuk, Woo, Ji Young, Kang, Gu Hyun, Kim, Han Myun, Choi, Hyun Young, Yang, Ik, Jang, Jae Ho, Kim, Jeong Won, Yoon, Sang Nam, Kim, Won Hee, Jang, Yong Soo, Park, Mi-Suk, Park, In Cheol, Lee, Jae Gil, Kim, Min Joung, Chung, Yong Eun, Lee, Jongmee, Kim, Baek-Hui, Lee, Chang Hee, Kim, Jung-Youn, Kang, Sanghee, Choi, Sung-Hyuk, Park, Yang Shin, Cho, Seong Whi, Park, Chan Woo, Chae, Gi Bong, Ohk, Taek Guen, Jeon, Yong-Hwan, Hong, Nurhee, Wi, Dae Han, Lee, Jun Hee, Kwon, Jung Nam, Lee, Seok Youn, Han, Weon-Cheol, Song, Young Cheol, Kim, Mi Jeong, Kwon, Jung Hyeok, Beak, Seoung Kyu, Kim, Sung Jin, Choi, Woo Ik, Kang, Yu Na, Shin, Cheong-Il, Lee, Dong Ho, Kang, Gyeong Hoon, Joo, Ijin, Yoon, Jeong Hee, Park, Ji Won, Park, Kyu Joo, Shin, Sang Do, Ryoo, Seung-Bum, Jeong, Seung-Yong, Ahn, Su Joa, Kim, Tae Han, Chang, Won, Kwon, Yoon-Hye, Shin, Sang Soo, Kim, Hee Joon, Kim, Ho Goon, Cho, Yong Soo, Choi, Yoo Duk, Kim, Bong Soo, Hyun, Chang Lim, Choi, Guk Myung, Jeong, In Ho, Kang, Kyeong Won, Kim, Seung Hyoung, Kim, Woo Jeong, Kang, Young Joon, and Kim, Kwang Pyo

Abstract

CT radiation is arguably carcinogenic. Results from single-centre studies, mostly retrospective, have advocated lowering the CT radiation dose for the diagnosis of appendicitis. However, adoption of low-dose CT has been slow. We aimed to assess the effectiveness of low-dose CT compared with standard-dose CT in the diagnosis of appendicitis in adolescents and young adults.

Published
2017
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