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The study evaluates the ability of tertiary hospital doctors to calculate drug doses and examines their workplace prescribing and calculation habits. Evidence indicates doctors expect a higher level of skill in drug-dose calculation from their colleagues than they can achieve themselves and that junior staff should be educated in drug-dose calculation to reduce risk of medication error.

A technique has been developed for repeated, direct, manometric study of the canine choledochoduodenal junction in conscious animals. The junction is characterized by a zone of elevated pressure interposed between the duodenum and common bile duct whose motor activity distinguishes it from these adjacent structures. Atropine sulfate administration resulted in a decrease in pressure in the junctional zone suggesting that a cholinergic mechanism is partly responsible for the maintenance of resting pressure in the canine choledochoduodenal junction.