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Your search keyword '"Messerer, Mahmoud"' showing total 22 results
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22 results on '"Messerer, Mahmoud"'

4. PD-L1 expression in PitNETs: Correlations with the 2022 WHO classification

Author

Harel, Ethan, Hewer, Ekkehard, La Rosa, Stefano, Brouland, Jean Philippe, Pitteloud, Nelly, Santoni, Federico, Brunner, Maxime, Daniel, Roy Thomas, Messerer, Mahmoud, and Cossu, Giulia

Abstract

and research question: Prognostic factors to predict the behavior of pituitary neuroendocrine tumors (PitNET) are scarce. PD-L1 expression was associated with prognosis in other neuroendocrine neoplasms and we analyzed PD-L1 expression in PitNET, according to the 2022 WHO classification.

Published
2025
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5. Pituitary neuroendocrine tumors: a model for neuroendocrine tumor classification

Author

Asa, Sylvia L., Mete, Ozgur, Cusimano, Michael D., McCutcheon, Ian E., Perry, Arie, Yamada, Shozo, Nishioka, Hiroshi, Casar-Borota, Olivera, Uccella, Silvia, La Rosa, Stefano, Grossman, Ashley B., Ezzat, Shereen, Pathology, International Pituitary, Asioli, Sofia, Bozkurt, Süheyla Uyar, Comunoglu, Nil, Cossu, Giulia, Earls, Peter, Gazioglu, Nuperi, Hickman, Richard A., Ikeda, Hidetoshi, Manojlovic-Gacic, Emilija, Messerer, Mahmoud, Öz, Buge, Pakbaz, Sara, Roncaroli, Federico, Saeger, Wolfgang, Turchini, John, and Yarman, Sema

Abstract

The classification of adenohypophysial neoplasms as “pituitary neuroendocrine tumors” (PitNETs) was proposed in 2017 to reflect their characteristics as epithelial neuroendocrine neoplasms with a spectrum of clinical behaviors ranging from small indolent lesions to large, locally invasive, unresectable tumors. Tumor growth and hormone hypersecretion cause significant morbidity and mortality in a subset of patients. The proposal was endorsed by a WHO working group that sought to provide a unified approach to neuroendocrine neoplasia in all body sites. We review the features that are characteristic of neuroendocrine cells, the epidemiology and prognosis of these tumors, as well as further refinements in terms used for other pituitary tumors to ensure consistency with the WHO framework. The intense study of PitNETs has provided information about the importance of cellular differentiation in tumor prognosis as a model for neuroendocrine tumors in different locations.

Published
2021
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6. Surgical Outcomes And Survival Patients With Leptomeningeal Metastasis: A Comparison Of Ventriculo-Peritoneal Shunt Vs. Rickham-Reservoir Placement For Palliative CSF Drainage.

Author

Alhalabi, Obada, Klein, Lukas, Büsken, Carmen, Juratli, Tareq, Mellal, Amine, Cossu, Giulia, Messerer, Mahmoud, Wasilewski, David, Buszello, Clara, Eyüpoglu, Ilker Y., Misch, Martin, Vajcozcy, Peter, Unterberg, Andreas W., El Damaty, Ahmed, Krieg, Sandro M., and Younsi, Alexander

Published
2024
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7. Fluorescence guidance in skull base surgery: Applications and limitations – A systematic review

Author

Suero Molina, Eric, Bruneau, Michael, Reuter, Gilles, Shahein, Mostafa, Cavallo, Luigi M., Daniel, Roy T., Kasper, Ekkehard M., Froelich, Sebastien, Jouanneau, Emanuel, Manet, Romain, Messerer, Mahmoud, Mazzatenta, Diego, Meling, Torstein R., Roche, Pierre-Hugues, Schroeder, Henry WS., Tatagiba, Marcos, Visocchi, Massimiliano, Prevedello, Daniel M., Stummer, Walter, and Cornelius, Jan F.

Abstract

Intraoperative fluorescence guidance is a well-established surgical adjunct in high-grade glioma surgery. In contrast, the clinical use of such dyes and technology has been scarcely reported in skull base surgery.

Published
2024
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8. The Barrow Neurological Institute Grading Scale as a Predictor for Delayed Cerebral Ischemia and Outcome After Aneurysmal Subarachnoid Hemorrhage: Data From a Nationwide Patient Registry (Swiss SOS)

Author

Neidert, Marian Christoph, Maldaner, Nicolai, Stienen, Martin Nikolaus, Roethlisberger, Michel, Zumofen, Daniel W, D’Alonzo, Donato, Marbacher, Serge, Maduri, Rodolfo, Hostettler, Isabel Charlotte, Schatlo, Bawarjan, Schneider, Michel M, Seule, Martin A, Schöni, Daniel, Goldberg, Johannes, Fung, Christian, Arrighi, Marta, Valsecchi, Daniele, Bijlenga, Philippe, Schaller, Karl, Bozinov, Oliver, Regli, Luca, Burkhardt, Jan-Karl, Fandino, Javier, Marbacher, Serge, D'Alonzo, Donato, Coluccia, Daniel, Schmid, Nicole, Zumofen, Daniel, Roethlisberger, Michel, Mariani, Luigi, Guzman, Raphael, Monsch, Andreas U, Bläsi, Stephan, Fung, Christian, Bervini, David, Beck, Jürgen, Raabe, Andreas, Goldberg, Johannes, Schöni, Daniel, Gralla, Jan, Zweifel-Zehnder, Antoinette, Gutbrod, Klemens, Müri, Rene, Maduri, Rodolfo, Thomas Daniel, Roy, Starnoni, Daniele, Messerer, Mahmoud, Levivier, Marc, Beaud, Valérie, Valsecchi, Daniele, Arrighi, Marta, Venier, Alice, Reinert, Michael, Kuhlen, Dominique E, Robert, Thomas, Rossi, Stefania, Sacco, Leonardo, Bijlenga, Philippe, Corniola, Marco, Schaller, Karl, Chicherio, Christian, Seule, Martin A, Ferrari, Andrea, Weyerbrock, Astrid, Hlavica, Martin, Fournier, Jean-Yves, Früh, Severin, Schatlo, Bawarjan, Burkhardt, Jan-Karl, Stienen, Martin N, Keller, Emanuela, Regli, Luca, Bozinov, Oliver, Maldaner, Nicolai, Finkenstädt, Sina, Neidert, Marian C, Brugger, Peter, and Mondadori, Christian

Published
2018
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10. Predictors of In-Hospital Death After Aneurysmal Subarachnoid Hemorrhage

Author

Stienen, Martin Nikolaus, Germans, Menno, Burkhardt, Jan-Karl, Neidert, Marian C., Fung, Christian, Bervini, David, Zumofen, Daniel, Röthlisberger, Michel, Marbacher, Serge, Maduri, Rodolfo, Robert, Thomas, Seule, Martin A., Bijlenga, Philippe, Schaller, Karl, Fandino, Javier, Smoll, Nicolas R., Maldaner, Nicolai, Finkenstädt, Sina, Esposito, Giuseppe, Schatlo, Bawarjan, Keller, Emanuela, Bozinov, Oliver, Regli, Luca, Serra, Carlo, Krayenbühl, Niklaus, Schöni, Daniel, Raabe, Andreas, Beck, Jürgen, Goldberg, Johannes, Mariani, Luigi, Guzman, Raphael, D’Alonzo, Donato, Coluccia, Daniel, Daniel, Roy Thomas, Starnoni, Daniele, Messerer, Mahmoud, Levivier, Marc, Valsecchi, Daniele, Arrighi, Marta, Venier, Alice, Reinert, Michael, Kuhlen, Dominique Emmanuelle, Ferrari, Andrea, Weyerbrock, Astrid, Hildebrandt, Gerhard, Hlavica, Martin, Fournier, Jean-Yves, and Corniola, Marco

Abstract

Supplemental Digital Content is available in the text.

Published
2018
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12. Differences in intraoperative sampling during meningioma surgery regarding CNS invasion – Results of a survey on behalf of the EANS skull base section

Author

Behling, Felix, Bruneau, Michaël, Honegger, Jürgen, Berhouma, Moncef, Jouanneau, Emmanuel, Cavallo, Luigi, Cornelius, Jan Frederick, Messerer, Mahmoud, Daniel, Roy Thomas, Froelich, Sébastien, Mazzatenta, Diego, Meling, Torstein, Paraskevopoulos, Dimitrios, Roche, Pierre-Hugues, Schroeder, Henry W.S., Zazpe, Idoya, Voormolen, Eduard, Visocchi, Massimiliano, Kasper, Ekkehard, Schittenhelm, Jens, and Tatagiba, Marcos

Abstract

and Research Question: Invasive growth of meningiomas into CNS tissue is rare but of prognostic significance. While it has entered the WHO classification as a stand-alone criterion for atypia, its true prognostic impact remains controversial. Retrospective analyses, on which the current evidence is based, show conflicting results. Discordant findings might be explained by different intraoperative sampling methodologies.

Published
2023
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13. Differences in intraoperative sampling during meningioma surgery regarding CNS invasion – results of a survey on behalf of the EANS skull base section

Author

Behling, Felix, Bruneau, Michael, Honegger, Jürgen, Berhouma, Moncef, Jouanneau, Emmanuel, Cavallo, Luigi, Cornelius, Jan Frederick, Messerer, Mahmoud, Daniel, Roy Thomas, Froelich, Sébastien, Mazzatenta, Diego, Meling, Torstein, Paraskevopoulos, Dimitrios, Roche, Pierre-Hugues, Schroeder, Henry W.S., Zazpe, Idoya, Voormolen, Eduard, Visocchi, Massimiliano, Kasper, Ekkehard, Schittenhelm, Jens, and Tatagiba, Marcos

Published
2023
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14. Endoscopic endonasal pituitary surgery: How we do it. Consensus statement on behalf of the EANS skull base section

Author

Bove, Ilaria, Solari, Domenico, Bruneau, Michaël, Berhouma, Moncef, Jouanneau, Emmanuel, Cornelius, Jan Frederick, Messerer, Mahmoud, Daniel, Roy Thomas, Froelich, Sebastien, Mazzatenta, Diego, Meling, Torstein, Paraskevopoulos, Dimitrios, Roche, Pierre-Hugues, Schoeder, Henry W.S., Zazpe, Idoya, Visocchi, Massimiliano, Kasper, Ekkehard, Tatagiba, Marcos, and Cavallo, Luigi Maria

Abstract

The use of an endoscope in skull base surgery provides a panoramic close-up view over the intracranial structures from multiple angles with excellent illumination, thus permitting greater extent of resection of tumors arising at sellar area, mostly represented by PitNet - Pituitary neuroendocrine tumors, with higher likelihood of preserving vital/intact gland tissue. For this refined specialty of neurosurgery, unique skills need to be acquired along a steep learning curve.

Published
2023
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15. Spinal epidural hematoma

Author

Messerer, Mahmoud, Dubourg, Julie, Diabira, Sylma, Robert, Thomas, and Hamlat, Abderrahmane

Abstract

Spinal epidural hematoma (SEH) is a rare neurosurgical emergency. SEH is characterized by an archetypal clinical presentation including abrupt spinal pain followed more or less rapidly by various degrees of neurological deficit. The diagnosis of SEH, often based on a clinical presumption, represents a clinical challenge. Several reports have outlined missed or delayed diagnosis due to unusual and confusing onsets or unawareness of this diagnosis by physicians. Therefore, physicians should keep in mind the possibility of SEH in their differential diagnosis when confronted with patients complaining of sudden onset of acute spinal pain with or without neurological sign, because the impact of a delayed diagnosis can be disabling catastrophic neurological sequelae. We suggest that SEH is a dynamic disease, which occurs in patients with an abnormal vasculature structural degenerative change. The bleeding is probably of multifactorial origin incriminating veins as well as arteries. Therefore, we proposed a classification of SEH, according to the most probable etiology whatever the associated factors, in six groups: spontaneous, secondary, iatrogenic, traumatic, recurrent, and idiopathic SEH.

Published
2012
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16. Diagnosis of childhood astrocytomas

Author

Hamlat, Abderrahmane, Saikali, Stephan, Diabira, Sylma, Messerer, Mahmoud, and Riffaud, Laurent

Abstract

Background: Astrocytomas are the most common brain tumours, accounting for 28 – 50% of all primary CNS tumours. Diagnosis of CNS tumours remains difficult because the varied and nonspecific presentations of CNS tumours in childhood. Objectives/method: The clinical presentations of CNS astrocytomas vary with their sites of location; therefore, a period of uncertainty often precedes diagnosis, and approximately 42% of patients with an intracranial process make several visits to various physicians between the onset and diagnosis. However, on clinical suspicion of a brain tumour, a wide range of neuroimaging techniques may be used to assess the diagnosis of paediatric brain lesions. In this review the authors, for ease of presentation, describe the clinical presentations of supratentorial, infratentorial and spinal cord astrocytomas as well as their radiological and pathological features, and discuss their differential diagnoses. Results/conclusions: Understanding and mastering the numerous imaging features of several subtypes of primary brain tumours affecting children, in addition to radiological features of non-tumoural disorders, remains a significant challenge and demands increased awareness of the paediatric brain diseases.

Published
2009
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17. Update in Cushing disease: What the neurosurgeon has to KNOW, on behalf of the EANS skull base section

Author

Eulate-Beramendi, Sayoa, Casajús, Ainhoa, Ollero, Lola, Niemann, Lynnette K., Fernández-Miranda, Juan Carlos, Bruneau, Michaël, Berhouma, Moncef, Cavallo, Luigi Maria, Cornelius, Jan Frederick, Daniel, Roy T., Froelich, Sebastien, Jouanneau, Emmanuel, Kasper, Ekkehard, Mazzatenta, Diego, Meling, Torstein R., Messerer, Mahmoud, Schroeder, Henry W.S., Tatagiba, Marcos, Visocchi, Massimiliano, Voormolen, Eduard H., and Zazpe, Idoya

Abstract

Cushing's disease is a state of chronic and excessive cortisol levels caused by a pituitary adenoma

Published
2022
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18. Surgical management of giant pituitary neuroendocrine tumors: Meta-analysis and consensus statement on behalf of the EANS skull base section

Author

Cossu, Giulia, Jouanneau, Emmanuel, Cavallo, Luigi M., Froelich, Sebastien, Starnoni, Daniele, Giammattei, Lorenzo, Harel, Ethan, Mazzatenta, Diego, Bruneau, Micheal, Meling, Torstein R., Berhouma, Moncef, Chacko, Ari G., Cornelius, Jan F., Paraskevopoulos, Dimitrios, Schroeder, Henry W.S., Zazpe, Idoya, Manet, Romain, Gardner, Paul A., Dufour, Henry, Cappabianca, Paolo, Daniel, Roy T., and Messerer, Mahmoud

Abstract

The optimal surgical treatment for giant pituitary neuroendocrine tumors(GPitNETs) is debated.

Published
2022
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19. Olfactory Groove Meningiomas: Comprehensive assessment between the different microsurgical transcranial approaches and the Endoscopic Endonasal Approaches, systematic review and metanalysis on behalf of the EANS skull base section

Author

Roa Montes de Oca, Juan Carlos, Gonçalves Estella, Jesús María, Nieto-Librero, Ana Belén, Galindo-Villardón, Purificación, Roa Ramírez, Carlos Julio, Gonçalves Sánchez, Jaime, Berhouma, Moncef, Cornelius, Jan Frederick, Daniel, Roy Thomas, Zazpe, Idoya, Froelich, Sébastien, Jouanneau, Emmanuel, Mazzatenta, Diego, Messerer, Mahmoud, Meling, Torstein, Paraskevopoulos, Dimitrios, Roche, Pierre-Hugues, Schroeder, Henry Werner Siegfried, Tatagiba, Marcos, Visocchi, Massimilliano, Voormolen, Eduard, Ekkehard, Kasper, and Bruneau, Michaël

Abstract

•OGM surgery is much more complex than a simple debate of “from above or from below” (transcranial vs endoscopic).•Lateral Sub-frontal and Superior Interhemispheric seem the most effective, superior and versatile approaches for OGM.•Minimally Invasive Transcranial approaches showed no inferiority in OGM sized <4 ​cm.•Endoscopic Endonasal Approaches showed inferior results in surgical and in functional outcomes for OGM.

Published
2022
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20. Management of cavernous sinus meningiomas: Consensus statement on behalf of the EANS skull base section

Author

Corniola, Marco V., Roche, Pierre-Hugues, Bruneau, Michaël, Cavallo, Luigi M., Daniel, Roy T., Messerer, Mahmoud, Froehlich, Sebastien, Gardner, Paul A., Gentili, Fred, Kawaswe, Takeshi, Paraskevopoulos, Dimitrios, Régis, Jean, Schroeder, Henry W.S., Schwartz, Theodore, Sindou, Marc, Cornelius, Jan F., Tatagiba, Marcos, and Meling, Torstein R.

Abstract

The evolution of cavernous sinus meningiomas (CSMs) might be unpredictable and the efficacy of their treatments is challenging due to their indolent evolution, variations and fluctuations of symptoms, heterogeneity of classifications and lack of randomized controlled trials. Here, a dedicated task force provides a consensus statement on the overall management of CSMs.

Published
2022
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