1. Motoric cognitive risk syndrome trajectories and incident dementia over 10 years
- Author
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Mullin, Donncha S., Gadd, Danni, Russ, Tom C., Luciano, Michelle, and Muniz-Terrera, Graciela
- Abstract
•Motoric Cognitive Risk (MCR) syndrome is a high-risk state for adverse health outcomes in older adults characterized by measured slow gait speed and self-reported cognitive complaints.•We used both Cox proportional hazards and competing risk regression methods to evaluate the risk of developing all-cause incident dementia over 10 years of follow-up for individuals with and without MCR.•The presence of MCR increased the risk of incident dementia (adjusted hazard ratio 2.34, 95%CI 1.14–4.78, p = 0.020), as did fewer years of education and higher depression symptoms.•MCR showed similar prognostic ability for dementia in a Scottish cohort as for other populations. MCR could identify a target group for early interventions of modifiable risk factors to prevent incident dementia.
- Published
- 2023
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