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The elemental composition of the lunar surface provides insights into mechanisms of the formation and evolution of the Moon1,2. The chemical composition of lunar regolith have so far been precisely measured using the samples collected by the Apollo, Luna and Chang’e 5 missions, which are from equatorial to mid-latitude regions3,4; lunar meteorites, whose location of origin on the Moon is unknown5,6; and the in situ measurement from the Chang’e 3 and Chang’e 4 missions7–9, which are from the mid-latitude regions of the Moon. Here we report the first in situ measurements of the elemental abundances in the lunar southern high-latitude regions by the Alpha Particle X-ray Spectrometer (APXS) experiment10aboard the Pragyan rover of India’s Chandrayaan-3 mission. The 23 measurements in the vicinity of the Chandrayaan-3 landing site show that the local lunar terrain in this region is fairly uniform and primarily composed of ferroan anorthosite (FAN), a product of the lunar magma ocean (LMO) crystallization. However, observation of relatively higher magnesium abundance with respect to calcium in APXS measurements suggests the mixing of further mafic material. The compositional uniformity over a few tens of metres around the Chandrayaan-3 landing site provides an excellent ground truth for remote-sensing observations.

Tigecycline (TIG) is a broad-spectrum antibiotic that has been approved for the treatment of a number of complicated infections, including community-acquired bacterial pneumonia. Currently it is available only as an intravenous injection that undergoes rapid chemical degradation and limits the use to in-patient scenarios. The use of TIG as an inhaled dry powder inhaler may offer a promising treatment option for patients with multidrug-resistant respiratory tract infections, such as Stenotrophomonas maltophilia(S. maltophilia). This study explores the feasibility of engineering an inhaled powder formulation of TIG that could administer relevant doses at a wide range of inhalation flow rates while maintaining stability of this labile drug. Using air-jet milling, micronized TIG had excellent aerosolization efficiency, with over 80% of the device emitted dose being within the respirable range. TIG was also readily dispersed using different inhaler devices even when tested at different pressure drops and flow rates. Additionally, micronized TIG was stable for 6 months at 25 °C/60% RH and 40 °C/75% RH. Micronized TIG maintained a low minimum inhibitory concentration (MIC) and minimum biofilm eradication concentration (MBEC) of 0.8 μM and >0.5 μM, respectively in S. maltophiliacultures in vitro. These results strongly suggest that the micronization of TIG results in a stable and respirable formulation that can be delivered via the pulmonary route for the treatment of lung infections.

The article focuses on the Womanifesto collective, a platform for artists from Southeast Asia, emphasizing community, inclusivity, and cross-generational dialogue as key aspects of their creative gatherings, exhibitions, and projects. It mentions the collective's approach contrasts with mainstream art practices, promoting genuine representation and meaningful conversations among women artists.

The present work focuses on the formulation and characterisation of undoped NiO and NiO codoped with Mg and Zn. The samples were characterized by x-ray diffractometer and ultraviolet-visible spectrophotometer. For the detection of elements present in the samples, energy dispersive x-ray analysis was employed. Two sets of codoped samples were prepared varying the amount of Mg and Zn. A set of codoped samples was prepared keeping the quantity of Mg at a fixed value and allowed the quantity of Zn to fluctuate. The second set of codoped samples was prepared keeping the extent of Zn at a fixed value and allowed the quantity of Mg to fluctuate. The bandwidth of undoped and codoped materials was computed raising Tauc plot. Crystallite size was computed following Scherrer formula.

Geocell is a soil reinforcement technique which is established to be a versatile method in terms of its efficiency in lateral confinement of the soil and cost-effectiveness. This study provides an overview of the bearing capacity and settlement characteristics of sand bed reinforced with coir geocells in comparison with HDPE–geocell-reinforced sand bed and unreinforced sand bed. A series of model plate load tests on the reinforced sand bed were conducted in a steel tank in the laboratory. The bearing capacity of coir geocell-reinforced sand was found to be two times higher than that of HDPE–geocells-reinforced sand bed. This paper also demonstrates the performance of HDPE and coir geocells with seashell as infill material in comparison with sand. Substantial results were obtained, and maximum bearing capacity was achieved for a combination of 20% seashell and 80% sand infilled in coir geocell. The preference of reinforcing soil with more economical and environment-friendly coir geocell and seashell is practicable as well as sustainable.