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Resting-state brain activity can serve as an objective measurement of unpleasantness associated with menopausal symptoms, which aids the selection of appropriate treatment and monitors its outcome.

We developed a 15.2-km submarine cable prototype which can accommodate up to 16 fiber pairs (FPs) of 125 μm standard cladding diameter 4-core uncoupled multicore fiber (UC-MCF). Fiber properties such as loss, chromatic dispersion, and inter-core crosstalk were measured and compared before and after cabling. We found that the cabling process, such as fiber rewinding, copper tubing and polyethylene coating completion, did not significantly change the fiber properties such as loss. To verify the influence of cabling process on long-haul transmission performance, we fabricated a 60.8-km length 4-core UC-MCF transmission span by serially splicing four FPs from the 15.2-km length cabled 4-core UC-MCF. An experimental loop transmission setup was established using the cabled transmission span, and Q-value was measured in real-time. The 120 wavelength multiplexed channels were transmitted. The five channels were modulated by 100 Gbps 34.7 GBd polarization multiplexed quadrature phase shift keying (PM-QPSK) signal and the other channels were loading channels shaped from amplified spontaneous emission (ASE). We changed the transmission direction one core at a time in the 4-core UC-MCF based transmission line to examine the effect of inter-core crosstalk on the transmission line. The −25-dB inter-core crosstalk caused negligible signal degradation in the 4-core UC-MCF and fan-in fan-out (FIFO) a total of 88 spans. Furthermore, we found that the 5,350-km transmission using cabled 4-core UC-MCF was limited by optical signal to noise ratio (OSNR). We integrated the transmission 4-core UC-MCF with the 4-core UC-MC-erbium doped fiber amplifier (EDFA) without using FIFO and clarified experimentally a Q-value improvement of 0.6 dB by removing half number of the FIFOs.

Electromethanogenesis refers to the bioelectrochemical synthesis of methane from CO2 by biocathodes. In an electromethanogenic system using thermophilic microorganisms, metagenomic analysis along with quantitative real-time polymerase chain reaction and fluorescence in situ hybridization revealed that the biocathode microbiota was dominated by the methanogen Methanothermobacter sp. strain EMTCatA1 and the actinobacterium Coriobacteriaceae sp. strain EMTCatB1. RNA sequencing was used to compare the transcriptome profiles of each strain at the methane-producing biocathodes with those in an open circuit and with the methanogenesis inhibitor 2-bromoethanesulfonate (BrES). For the methanogen, genes related to hydrogenotrophic methanogenesis were highly expressed in a manner similar to those observed under H2-limited conditions. For the actinobacterium, the expression profiles of genes encoding multiheme c-type cytochromes and membrane-bound oxidoreductases suggested that the actinobacterium directly takes up electrons from the electrode. In both strains, various stress-related genes were commonly induced in the open-circuit biocathodes and biocathodes with BrES. This study provides a molecular inventory of the dominant species of an electromethanogenic biocathode with functional insights and therefore represents the first multiomics characterization of an electromethanogenic biocathode.