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The progress in computer technology and the increased use of finite element analysis in the medical field by nonengineers and medical researchers lead us to believe that there is a need to develop a systematic approach to validate a finite element model (FEM), of a human orbit, that simulates part of the maxillofacial skeleton and to investigate the effects and the clinical significance of changing the geometry, boundary conditions, that is, muscle forces, and orthotropic material properties on the predictive outcome of an FEM of a human orbit.

The purpose of the study was to compare the preemptive analgesic effect of celecoxib, a cyclooxygenase 2 inhibitor, with a traditional nonsteroidal anti-inflammatory drug, ibuprofen, in patients after minor oral surgery procedures.

The purpose of this study was to develop a finite element model (FEM) of a human orbit, of 1 patient, who had an orbital blow-out fracture, to study the effect of using a “stiffness-graded” (SG) biodegradable implant on the biomechanics of bone-fracture repair.

The purpose was to study the biomechanics of bone fracture repair, of the orbital floor, using osteosynthetic bioresorbable implant and how to improve the implant design.

The purpose of this study was to develop a finite element model (FEM) of a human orbit, who experienced a pure orbital blowout fracture, to study the effect of the geometrical mismatch-induced stresses on the orbital floor/graft interface and how to improve the graft design when restoring the orbital floor.

To develop a finite element model (FEM) to study the effect of the vascular wall compliance on blood flow at the graft/recipient vessel junction.

To investigate the changes in noradrenaline concentrations in transplanted arterial grafts in rats, 31 female rats 4 to 6 weeks old of the AO/KsOC strain were operated on. Femoral arterial grafts were anastomosed to carotid arteries and compared with control femoral segments. Six rats were included in each follow-up group at 0, 1, 4, and 12 weeks, and there were seven rats in the 20-week follow-up group. High-performance liquid chromatography was used to determine the concentrations of noradrenaline. The operation itself decreased noradrenaline concentrations in the grafts to 76 percent of that in the control segments. One week after the operation, the noradrenaline concentration had fallen to 1.7 percent of the control values and started to recover thereafter. One month after the operation, it was 23 percent; at 3 months, it was 31 percent; and at 5 months, it was 43 percent of control values. The decrease from time 0 to 1 week was significant (p0.001), as was the increase from 1 week to 20 weeks (p0.004). Noradrenaline concentrations had fallen significantly 1 week after the operation and thereafter they increased to levels comparable to those seen in the immediate postoperative period.