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Abstract: This article analyses the long term incidence of cancer disease in the vicinity of nuclear power plant at Jaslovské Bohunice. The data on the incidence of cancer were summarized by year and by regional district for men and women separately. The main study region was the district Trnava with the districts Nitra and Levice used as a reference teritory. The actual figures are from 1968 till 1990 with a trend calculated up to the year 2000. Mortality was evaluated from the point of view of the percentage of premature deaths and the potentially lost years of life. This analysis was made for a period from 1980 till 1990 for men and women separately for each municipality in the Tmava district. Neither a higher incidence of cancer nor an accelerated dynamics of cancer formation was found in the vicinity of nuclear power plant. Mortality is therefore uniform within the whole Trnava district and no exceptional situation was found within the regional continuity.