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Your search keyword '"Ravikumar, Reena"' showing total 4 results
Start Over Author "Ravikumar, Reena" Publication Type Magazines
4 results on '"Ravikumar, Reena"'

1. The Impact of Neoadjuvant Treatment on Survival in Patients Undergoing Pancreatoduodenectomy With Concomitant Portomesenteric Venous Resection: An International Multicenter Analysis

Author

Machairas, Nikolaos, Raptis, Dimitri A, Velázquez, Patricia Sánchez, Sauvanet, Alain, Rueda de Leon, Alexandra, Oba, Atsushi, Koerkamp, Bas Groot, Lovasik, Brendan, Chan, Carlos, Yeo, Charles J., Bassi, Claudio, Ferrone, Cristina R., Kooby, David, Moskal, David, Tamburrino, Domenico, Yoon, Dong-Sup, Barroso, Eduardo, de Santibañes, Eduardo, Kauffmann, Emanuele F., Vigia, Emanuel, Robin, Fabien, Casciani, Fabio, Burdío, Fernando, Belfiori, Giulio, Malleo, Giuseppe, Lavu, Harish, Hartog, Hermien, Hwang, Ho-Kyoung, Han, Ho-Seong, Marques, Hugo P., Poves, Ignasi, Domínguez-Rosado, Ismael, Park, Joon-Seong, Lillemoe, Keith D., Roberts, Keith, Sulpice, Laurent, Besselink, Marc G., Abuawwad, Mahmoud, Del Chiaro, Marco, de Santibañes, Martin, Falconi, Massimo, D'Silva, Mizelle, Silva, Michael, Hilal, Mohammed Abu, Qadan, Motaz, Sell, Naomi M., Beghdadi, Nassiba, Napoli, Niccolò, Busch, Olivier R. C., Mazza, Oscar, Muiesan, Paolo, Müller, Philip C., Ravikumar, Reena, Schulick, Richard, Powell-Brett, Sarah, Abbas, Syed Hussain, Mackay, Tara M., Stoop, Thomas F., Gallagher, Tom K., Boggi, Ugo, van Eijck, Casper, Clavien, Pierre-Alain, Conlon, Kevin C. P., and Fusai, Giuseppe Kito

Abstract

Supplemental Digital Content is available in the text

Published
2021
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2. A randomized trial of normothermic preservation in liver transplantation

Author

Nasralla, David, Coussios, Constantin C., Mergental, Hynek, Akhtar, M. Zeeshan, Butler, Andrew J., Ceresa, Carlo D. L., Chiocchia, Virginia, Dutton, Susan J., García-Valdecasas, Juan Carlos, Heaton, Nigel, Imber, Charles, Jassem, Wayel, Jochmans, Ina, Karani, John, Knight, Simon R., Kocabayoglu, Peri, Malagò, Massimo, Mirza, Darius, Morris, Peter J., Pallan, Arvind, Paul, Andreas, Pavel, Mihai, Perera, M. Thamara P. R., Pirenne, Jacques, Ravikumar, Reena, Russell, Leslie, Upponi, Sara, Watson, Chris J. E., Weissenbacher, Annemarie, Ploeg, Rutger J., and Friend, Peter J.

Abstract

Liver transplantation is a highly successful treatment, but is severely limited by the shortage in donor organs. However, many potential donor organs cannot be used; this is because sub-optimal livers do not tolerate conventional cold storage and there is no reliable way to assess organ viability preoperatively. Normothermic machine perfusion maintains the liver in a physiological state, avoids cooling and allows recovery and functional testing. Here we show that, in a randomized trial with 220 liver transplantations, compared to conventional static cold storage, normothermic preservation is associated with a 50% lower level of graft injury, measured by hepatocellular enzyme release, despite a 50% lower rate of organ discard and a 54% longer mean preservation time. There was no significant difference in bile duct complications, graft survival or survival of the patient. If translated to clinical practice, these results would have a major impact on liver transplant outcomes and waiting list mortality.

Published
2018
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