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Lactobacilli strains were isolated from the milk of domestic animals for potential probiotic. A total of 120 milk samples (40 each from buffalo, cow and goat) were analyzed and 110 Lactic Acid Bacteria (LAB) were identified, out of these 43 were identified as probiotics, (L. acidophilus, L. bulgaricus, L. plantarum, L. lactis and L. rhamnosus). Out of these, 11 isolates were potential probiotics, which includes L. plantarum (C1, C4, C7, G7, G8 and B14) and L. rhamnosus (B13, C5, G4, G10 and G18). Their bacteriocins showed a broad inhibitory spectrum against the indicator organisms tested. The bacteriocins produced by L. plantarum (C4, G7) and L. rhamnosus (G18) showed prominent antimicrobial activity, resistance to heat at 121[degrees]C and tolerate acidic pH 3 but sensitive to pH 9 indication strong probiotic potential. These isolated LABS, exhibiting excellent probiotic characteristics, can be use in the protection and improvement of intestinal microbial flora and contribute health benefits to consumers. Keywords: Lactic acid bacteria | Lactobacillus | Acid tolerance | Bile tolerance | Probiotic | Bacteriocin | Antibacterial activity., Introduction Lactic acid bacteria (LAB) widely distributed in the nature and occurring indigenous microflora in raw milk that play an important role in many food and feed fermentations with increased [...]

Central nervous system disorders are expected to profoundly impact the global healthcare needs of the human community in this era. Senile decay of neurons is (Alzheimers Disease) AD. The hallmark of the pathophysiology of AD disease has two pivotal features: extracellular beta-amyloid deposition and intracellular tau hyperphosphorylation. New medicine-based psychoactive treatments have met with modest effectiveness due to the multifactorial nature of these diseases. As a result, there is an increasing need for new products that can address various receptors and enhance behavioral abilities independently or in tandem with traditional medications. Herbal products focused on conventional expertise have recently been widely popular in developed and developing countries. Ayurveda is a medical science that deals with the treatment of diseases using naturally occurring plant products. Ayurveda claims to have a large number of neuroprotective herbs. This review discusses the pharmacological effects and therapeutic properties of In vivo, In vitro, In silico and human clinical trials of (Bacopa monnieri) BM against AD.

Seventy samples of groundwater were collected from different parts of Yavatmal District, India and analyzed. The results of this analysis were compared with the WHO water quality standards. The groundwater quality in this district showed slightly seasonal variation while the data computed in Water Quality Index (WQI) calculator. The WQI was varied from 73.0 to 80.2 during pre monsoon and 68.7 to 72.4 in post monsoon season, which showed slightly seasonal variation. This may be attributed to surface runoff and percolation process. The results showed that, the water in these areas are bacteriologically not safe and need treatment before it is used for drinking.

Water quality index (WQI) has been calculated for different groundwater sources i.e. dug wells, bore wells and tube wells at Khaperkheda region, Maharashtra (India). Twenty two different sites were selected in post monsoon, winter and summer season. And water quality index was calculated using water quality index calculator given by National Sanitation Foundation (NSF) information system. The calculated WQI showed fair water quality rating in post monsoon season which then changed to medium in summer and winter seasons for dug wells, but the bore wells and hand pumps showed medium water quality rating in all seasons where the quality was slightly differs in summer and winter season than post monsoon season, so the reasons to import water quality change and measures to be taken up in terms of groundwater quality management are required.