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Your search keyword '"Thériault, Olivier"' showing total 2 results
Start Over Author "Thériault, Olivier" Publication Type Magazines
2 results on '"Thériault, Olivier"'

1. Biophysical, Molecular, and Pharmacological Characterization of Voltage-Dependent Sodium Channels From Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Author

Moreau, Adrien, Mercier, Aurélie, Thériault, Olivier, Boutjdir, Mohamed, Burger, Bettina, Keller, Dagmar I., and Chahine, Mohamed

Abstract

The ability to differentiate patient-specific human induced pluripotent stem cells in cardiac myocytes (hiPSC-CM) offers novel perspectives for cardiovascular research. A number of studies, that reported mainly on current-voltage curves used hiPSC-CM to model voltage-gated Na+channel (Nav) dysfunction. However, the expression patterns and precise biophysical and pharmacological properties of Navchannels from hiPSC-CM remain unknown. Our objective was to study the characteristics of Navchannels from hiPSC-CM and assess the appropriateness of this novel cell model.

Published
2017
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