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Boost derived converters are widely employed due to their simplicity and high reliability when it comes to obtaining a higher voltage level. However, the existence of right half-plane (RHP) zeros in the control-to-output transfer function deteriorates the dynamic performance of this category converters. Integrated coupling between the power inductor and the filter inductor is an effective method to alleviate the influence of RHP zeros. This paper puts forward a novel coupled inductor boost with an RLparallel damping (CIB-RLPD) network, where the input inductor, output inductor, and auxiliary inductor used to achieve RHP elimination have been integrated into a single magnetic core. The operating principle and small-signal analysis of the novel converter in continuous conduction mode (CCM) is discussed in detail. By an optimal design of the parameters of the damping network according to the Routh–Hurwitz Criterion, a novel converter with a good dynamic performance within a wide input voltage range can be achieved, which is a good candidate for renewable applications, particularly for spacecraft power systems. For the sake of comparison, the allowable operation duty ratio range and frequency response of the transfer function for both the original coupled inductor boost (CIB) and the proposed CIB-RLPD are presented in this paper. Finally, prototypes of the CIB and CIB-RLPD are implemented in the laboratory and experimental verifications are given to demonstrate the effectiveness of theoretical predictions.

A coupled inductor filter (CIF) is a good candidate for reducing current ripple, and improving the power density of switching power. However, because the resonance frequency of its series branch is easily affected by non-ideal factors, such as the inductance production process, ambient temperature, device aging, among others, it is usually unable to optimize its effect in practice. To solve this problem, by considering the ripple-free input current boost converter as an example, this paper proposes a novel method that adds a variable inductor (VI) into the AC resonant branch of a CIF. The value of the VI is adjusted online to optimize the ripple cancellation effect by comparing the peak-to-peak current ripples in the main power inductor and the AC branch inductor. In the aforementioned scheme, the voltage-controlled current source (VCCS) in the closed loop control circuit is critical for achieving a rapid and stable regulation of the VI. Therefore, a 1/∛scompensator is adopted to provide a sufficient stability margin under various operating conditions. Finally, the input characteristics of a 500 W boost converter are measured and presented in this study. The obtained results demonstrate that the total inductor current ripple peak-to-peak values at each operating point are within 85 mA, which confirms the correctness of the theoretic analyses.

In a photovoltaic (PV) power generation system, a power interface converter is required to manage the power flow between the PV cells, battery, or load. Conventionally, while designing loop controller parameters, an ideal current or voltage source with a fixed resistor is adopted to simulate the panel characteristics However, significant differences exist between the actual performance of real panels and that of the above two alternatives; additionally, controllers designed with a definite equivalent model may lack a response. In this study, the small-signal model of a power interface converter, comprising the dynamic characteristics of PV cells, was developed for different operating modes to solve the aforementioned problems. On this basis, frequency response comparisons of the power stage transfer function were used to analyze the stability margin with parameter variations. Consequently, it was concluded that the dynamic capacitance and equivalent output resistance of the PV cells could not be ignored. Therefore, a controller design approach for the worst case was developed. The mathematical analysis was verified based on a prototype simulation and a thorough investigation of the waveforms.

Adipose tissue remodelling is considered a critical pathophysiological hallmark of obesity and related metabolic diseases. Berberine (BBR), a natural isoquinoline alkaloid, has potent anti-hyperlipidaemic and anti-hyperglycaemic effects. This study aimed to explore the role of BBR in modulating adipose tissue remodelling and the underlying mechanisms. BBR protected high fat diet (HFD)-fed mice against adiposity, insulin resistance and hyperlipidemia. BBR alleviated adipose tissue inflammation and fibrosis by inhibiting macrophage infiltration, pro-inflammatory macrophage polarization and the abnormal deposition of extracellular matrix, and the effect was mediated by BBR directly binding and activating the deacetylase Sirtuin 3 (SIRT3) and suppressing the activation of the mitogen-activated protein kinases and nuclear factor-κB signalling pathways. Furthermore, BBR decreased microRNA-155-5p secretion by macrophages, which in turn ameliorated liver injury. Moreover, BBR mitigated inflammatory responses in both LPS-stimulated macrophages and TNF-α-treated adipocytes and suppressed macrophage migration towards adipocytes by activating SIRT3. Collectively, this study revealed that BBR improved adipose tissue remodelling, and subsequently inhibited the secretion of microRNA-155-5p by macrophages, which alleviated adiposity, insulin resistance and liver injury in obese mice. The modulation of adipose tissue remodelling by activating SIRT3 could contribute to the anti-hyperlipidemic and anti-hyperglycemic effects of BBR.

Diamond-like carbon (DLC) films containing single copper (Cu), single nickel (Ni) and double nickel/copper interlayers were fabricated on LY-12 aluminum (Al) alloy by electrodeposition. The influence of different interlayers on the microstructure, microhardness, friction and wear properties and electrochemical behavior of the films was investigated. The morphological results show that the porosity of DLC films was reduced and the particles were refined after the introduction of a double interlayer. Raman and X-ray photoelectron spectroscopy results confirm that the amorphous characteristics of DLC films containing nickel and copper interlayers were enhanced, and the content of sp3carbon in the films was increased. Besides, an optimal microhardness of 210.67 HV was achieved due to the high sp3carbon content of the double nickel/copper–DLC film. Meanwhile, the nickel/copper–DLC film possessed excellent wear resistance, which benefits from the synergistic effect of the copper and nickel interlayer. Nickel as the supporting layer and copper as the lubricating layer alleviated the wear and friction of the film. Simultaneously, the deposition of a double interlayer increased the density of the film, which further prevented the invasion of corrosion ions, so the film had superior electrochemical properties.

Orthostatic hypotension (OH) is a common non-motor symptom in Parkinson’s disease (PD) and is linked with increased mortality risk among the elderly. Although the locus coeruleus (LC) is the major source of noradrenaline (NA) modulation in the brain, its role in the pathogenesis of OH in PD remains largely elusive. Here we examined 44 well characterized postmortem brains of PD patients and available clinical data to explore the relationship between OH and LC pathology in PD. Our results failed to indicate that the LC pathology as well as the substantia nigra pathology were robustly associated with the presence of OH in PD patients, suggesting targeting LC norepinephrinergic system alone may not be sufficient to treat OH in PD.

In 5G systems and beyond, traditional generic service models are no longer appropriate for highly customized and intelligent services. The process of reinventing service models involves allocating available resources, where the performance of service processes is determined by the activity node with the lowest service rate. This paper proposes a new bottleneck-aware resource allocation approach by formulating the resource allocation as a max-min problem. The approach can allocate resources proportional to the workload of each activity, which can guarantee that the service rates of activities within a process are equal or close-to-equal. Based on the business process simulator (i.e., BIMP) simulation results show that the approach is able to reduce the average cycle time and improve resource utilization, as compared to existing alternatives. The results also show that the approach can effectively mitigate the impact of bottleneck activity on the performance of service processes.

•The laser sintering and invalidating composite (LSIC) scanning method is proposed.•The large-spot laser scanning is used to sinter the inside of the sample efficiently，in order to realize high tensile strength of the parts.•The small-spot laser scanning is used to invalidate the profile of the sample，in order to realize high accuracy of the parts.•Composite scanning method solves the problem of the inter-limitation of tensile strength and accuracy of laser sintering forming.

Helicobacter pylori(H. pylori) was reported to be associated with gastric carcinogenesis. Resistin-like molecule beta (RELMβ), a recently described goblet cell-specific protein, was demonstrated to aberrantly express in gastric cancer and correlated with its clinicopathological features. This study aimed to examine the association between H. pyloriand RELMβ expression in gastric carcinoma and precursor lesions. H. pyloriinfection and RELMβ expression were immunohistochemically evaluated in gastric biopsies from 230 patients. The biopsies consisted of normal gastric mucosa (n=20), mucosa with chronic gastritis (n=41), intestinal metaplasia (n=42), dysplasia (n=31), intestinal-type adenocarcinoma (n=56), and diffuse-type adenocarcinoma (n=40). RELMβ expression was measured in gastric biopsies after H. pylorieradication therapy in a subgroup of 32 patients. Cultured gastric cancer cell line SGC-7901 was infected with H. pyloristrains, and RELMβ expression was detected by reverse transcription PCR, real-time PCR and Western blotting. Higher RELMβ immunoreactivity was observed in H. pylori-positiveintestinal metaplasia (P=0.003), dysplasia (P=0.032), intestinal-type (P=0.037) and diffuse-type adenocarcinomas (P=0.001) than in H. pylori-negativespecimens. Expression rates of RELMβ in dysplasia (P=0.005), intestinal-type adenocarcinoma (P<0.001), and diffuse-type adenocarcinoma (P=0.001) were significantly correlated with the grade of H. pyloridensity. In addition, H. pylorieradication reduced the RELMβ intensity in intestinal metaplasia (P=0.001). Infection of gastric cancer SGC-7901 cells with cag pathogenicity island (PAI)-positive H. pyloriTN2, but not with its PAI totally deleted mutant (TN2-ΔPAI) for 4–8 h, resulted in enhanced protein and transcript levels of RELMβ (P<0.05). In summary, our study suggested that H. pyloriinfection facilitated the expression of RELMβ in gastric garcinoma and precursor lesions.

Lipophagy is a lysosomal lipolytic pathway that complements the actions of cytosolic neutral lipases. Chaperon-mediated autophagy (CMA) triggers lipid droplets (LDs) breakdown, to initiate lipolysis via either cytosolic lipases or macroautophagy. SIRT3, a mitochondrial NAD+-dependent deacetylase, regulates the acetylation status and activity of many substrates involving in energy metabolism. However, the role of SIRT3 in regulating lipophagy is controversial. The current study showed that SIRT3 expression was decreased and the macroautophagy flux was blocked in the primary hepatocytes from high-fat diet fed mice and P/O (palmitic acid and oleic acid mixture) treated AML12 mouse hepatocytes, compared with the corresponding controls. SIRT3 overexpression promoted macroautophagy in LDs from P/O-treated hepatocytes through activating AMP-activated protein kinase (AMPK) and unc-51-like kinase 1, to boost LDs digestion. Gain of SIRT3 expression stimulated the formation of lysosome-associated membrane protein 2A (LAMP-2A)-heat shock cognate 71 kDa protein (HSC70)-perilipin-2 (PLN2) complex, to promote CMA process and reduce the stability of LDs in hepatocytes. Moreover, SIRT3 reduced the expression of stearoyl-CoA desaturase 1, to suppress lipogenesis. In addition, SIRT3 overexpression promoted LDs dispersion on detyrosinated microtubules, and directly deacetylated long-chain acyl-CoA dehydrogenase to enhance mitochondrial energetics. Taken together, SIRT3 ameliorates lipotoxicity in hepatocytes, which might be a potential target for the treatment of nonalcoholic fatty liver disease.

The Xisha Block is a minor one in the South China Sea and an important tectonic unit in the northwestern part of the region. Zircon SHRIMP U-Pb ages for three volcanic intrusive core samples from Xike-1, an exploratory well penetrating the bioherms of the Xisha Islands. The core samples are from the Miocene reef carbonate bedrock and are recognized as dark-gray biotite-hornblende gabbro, gray fine-grained biotite diorite, and gray fine-grained granite, respectively. Zircon cathodoluminescence (CL) images and trace Th, U and Pb compositions of the zircons show that these rocks are of volcanic intrusive origin. Zircon SHRIMP U-Pb dating yielded six groups of ages, ranging from 2451-1857 Ma to early Cretaceous, which indicate that the formation and evolution of the Xisha Block was affected by the evolution and closure of Neotethys Ocean, probably within its eastern extension into South China Sea. Both old, deep-sourced material, including fragments from Rodina supercontinent, and recent mantle-derived magma products contributed to the emergence and formation of the Xisha block. The SHRIMP U-Pb results also proved that this process differed from that of the Kontum massif, the Hainan Block, and the South China Block, but is similar to that of the Nansha and Zhongsha blocks. The process was associated with the effects of Yanshanian magmatism induced by subduction mechanisms of the Paleo-Pacific Plate or the reworking of the multiple magmatisms since the Early to mid-Yanshanian, possibly jointly experienced by the Xisha-Zhongsha-Nansha Block.

The control strategy of shifting actuators is the most crucial part in the development of automated mechanical transmission (AMT) system. To solve problems such as large workload of parameters tuning and worse disturbance-rejecting ability under traditional PID for selecting and shifting gear in present industry, a new strategy based on active disturbance rejection control (ADRC) was proposed. The extended state observer (ESO) was used to observe and compensate total disturbances in real time to achieve precise closed-loop control for shifting motor position. The Hardware-In-the-Loop (HIL) experiments show that the speed of selecting actuator moving to target position under ADRC is 14.3% faster than that of PID, and the position deviation of selecting actuator is 0.9mm under ADRC with an external disturbance of 1N·m added, which is 59.1% less than that under PID. And the target gear tracking test indicates that the total shifting time under ADRC can be reduced by 2.37% to 5.08% compared with PID. This strategy has better control accuracy and robustness under load mutation condition compared to traditional PID.

The indicated torque (TQin) is regarded as a key variable for both control and diagnostics of the combustion of gasoline engines. Due to the limitation in available sensors, the TQin, however, cannot be measured directly. In this paper, a real-time TQinestimation approach is presented, based on the instantaneous crankshaft rotational speed (ω) signal. A physics-based control-oriented model ω is developed for a four-cylinder gasoline direct engine, which takes account the load torque, friction torque and the indicated torque. The proposed observer are validated both in simulation and experiments at steady-state operating and during transients. Results show that deviation between the observed value and the actual value is within 4%. The optimized model based observer shows greater potential in engine combustion feedback control.

For the engine-dynamometer test bench, the engine torque output (Te) is controlled by the test bench controller through the manipulation of the engine acceleration pedal position (up). Due to the nonlinearities and uncertainties between upand Te, the time-consuming control parameters scheduling is usually necessary using conventional controllers. In this paper, a composite disturbance observation based torque controller is proposed. The nonlinearity, from upto the torque demand in the engine control unit, is compensated by an adaptive feed forward controller, based on the inverse of a self-learning MAP by stochastic gradient decent. All other nonlinearities and uncertainties are lumped as total disturbance. By estimating the total disturbance using the extended state observer in real-time, the plant is enforced as a first-order system to be easily controlled by a simple proportional controller. The proposed controller is validated in a high-fidelity GT-SUITE simulation model. Results show that average absolute torque tracking error is 1.62N·m over the suburban part in European Transient Cycle without the need of control parameters scheduling.

Fuel consumption of a city bus is greatly influenced by driving style, and driving assistance systems (DAS) is a key technology to encourage driving style improvement. In the research reported here, we construct a real-time DAS for a city bus based on a decision tree algorithm. The DAS aims to reduce fuel consumption by encouraging three behaviors: reduced rates of acceleration, reduced depth of acceleration pedal and early upshifting through the gears. Using the proposed DAS, we establish a driver experiment platform with a driving simulator. Then, we design an experiment for 4 non-professional drivers with various driving experience to determine the effects of DAS on their driving style. The driving simulator experiment results show that all the drivers exhibited an observable change in acceleration pedal depth distribution, acceleration pedal positive gradient distribution, and shift timing. These findings indicated that through the real-time guidance on the manipulation of the accelerator pedal position and gear, the drivers could obey the devices from DAS to a certain extent, so the eco-driving device can help drivers change their driving style.

The Xigaze ophiolite represents one of the most prominent occurrences of Neo-Tethyan ocean remnants in the central part of the Yarlung-Zangbo suture zone, southern Tibet, which marks the collision of the Indian and Eurasian plates during the Jurassic and Cretaceous. Abundant veins and bands of rodingite, which are spatially related to gabbro and diabase dykes and intermingled with serpentinized mantle peridotite, were found in the ophiolite sequence, extending from Jiding to Luqu, Bairang and Baigang. The gabbro as well as diabase formed in a back-arc basin that developed by subduction of the Tethys ocean in response to the convergence of India and Eurasia. Both rodingite and gabbro/diabase show the same geochronological and geochemical behavior, thus demonstrating the genetic relationship of these lithological types with oceanic lithosphere. Rodingitization can be seen as a Ca-involving metasomatic process that is genetically linked to serpentinization; the Xigaze rodingites typically show a gain in Ca and a loss of Na and K. The mineral assemblages of the rodingites are highly variable and can be divided into two groups. Group I rodingite, where prehnite is absent, consists of the subgroups clinozoisite rodingite, garnet–diopside rodingite and garnet – vesuvianite rodingite. The grossular-rich (hydro) garnet may contain up to 13.7 wt% TiO2, essentially as morimotoite component (23 mol%). In group II rodingite, prehnite is present and vesuvianite absent; subgroups are prehnite rodingite and prehnite–garnet rodingite. Group I rodingites mainly occur in deformed schistose serpentinites and have experienced a more intense rodingitization in a SiO2 undersaturated environment than those of group II. Group II rodingites occur along extensional fractures in serpentinized peridotite. Their setting is SiO2 saturated and reflects a later metasomatic fluid/rock interaction that occurred at shallow crustal levels. Group I rodingites presumably formed within the oceanic crust and were later involved in a subduction-zone environment at high pressures in the early stages of the geodynamic evolution of the Xigaze ophiolite, with a final late-stage imprint at shallow crustal levels. Group II rodingites are interpreted to have formed during late-stage ductile and brittle deformation events at shallow crustal levels, when the uplift process of the mantle section was nearly completed. Rodingites may thus represent an important chronological marker within ophiolites, which may help to evaluate the sequence of processes such as early magmatic intrusions, rodingitization, serpentinization, late basic intrusions, shallow crustal level alterations.

The submerged gate filling processes were investigated through the use of particle image velocimetry (PIV) measurements, numerical simulation and castings production. The results showed that the submerged gate filling can improve the mold filling conditions, which may reduce the occurrence of inclusion defects during casting production. The liquid free surface in the mold rose slowly and smoothly during the filling process, which could reduce the occurrence of oxide film inclusion defects. The flow velocity decreased from the gate to the mold, which may reduce the severity of the liquid impingement that causes sand wash defects. The liquid flow inside the mold, with the exception of the flow path region, was primarily quiescent and the distance from the submerged gate to the free surface was relatively small. Therefore, low density slag in the liquid could be carried to the liquid free surface by the fluid flow and by the slag’s buoyancy.

Glioma is one of the most common malignant central nervous system tumors in humans. Schisandrin B (Sch B) has been confirmed to cause the proliferation and invasion of glioma cells. In the present study, the potential mechanism underlying the antitumor effect of Sch B on glioma cells was investigated. The glioma cell lines, U251 and U87, were exposed to Sch B, and the cell viability, apoptosis, migration, and invasion were determined using the MTT assay, flow cytometry, and transwell assay, respectively. Then, the effects of HOTAIRand miR-125aon tumor biology and the mammalian target of rapamycin (mTOR) protein expression in cell lines exposed to Sch B were investigated. The results showed that Sch B decreased HOTAIRexpression and increased miR-125a-5pexpression. HOTAIRoverexpression decreased miR-125aexpression and increased mTOR expression in cells with the treatment of Sch B. The miR-125ainhibitor reversed the effects of HOTAIRdownregulation on cell proliferation and migration. On co-incubation with rapamycin, a specific mTOR inhibitor, the cell viability, migration, and invasion were decreased and cell apoptosis was increased in two cell lines exposed to Sch B after the treatment of pcDNA-HOTAIR. In conclusion, Sch B played an inhibitory role in the proliferation and invasion of glioma cells by regulating the HOTAIR–micoRNA-125a–mTOR pathway.

Altered progesterone responsiveness leads to female infertility and cancer, but underlying mechanisms remain unclear. Mice with uterine-specific ablation of GATA binding protein 2(Gata2) are infertile, showing failures in embryo implantation, endometrial decidualization, and uninhibited estrogen signaling. Gata2deficiency results in reduced progesterone receptor (PGR) expression and attenuated progesterone signaling, as evidenced by genome-wide expression profiling and chromatin immunoprecipitation. GATA2 not only occupies at and promotes expression of the Pgrgene but also regulates downstream progesterone responsive genes in conjunction with the PGR. Additionally, Gata2knockout uteri exhibit abnormal luminal epithelia with ectopic TRP63 expressing squamous cells and a cancer-related molecular profile in a progesterone-independent manner. Lastly, we found a conserved GATA2-PGRregulatory network in both human and mice based on gene signature and path analyses using gene expression profiles of human endometrial tissues. In conclusion, uterine Gata2regulates a key regulatory network of gene expression for progesterone signaling at the early pregnancy stage.

This study aims to investigate the effect of 4 different dialysate temperatures on blood pressure during hemodialysis for patients with hypertension.

Shallow inland water resources has a large potential for development. To Jiyang shallow groundwater for example, through the regular ion-test analysis, Piper diagram and hydrogeochemical characteristics, the results show that: (1) The type of chemistry of shallow groundwater inland were Cl·SO4-Mg·Na·Ca; (2) The salt water area is relatively fixed, there is no expansion or decreasing trend; (3) The level flow of shallow groundwater is slow and water rock interaction is strong, that is not conducive to the shallow groundwater quality improvement, changing the runoff conditions of shallow groundwater is essential way for shallow groundwater resources exploitation.

Inland plain shallow saline water has great exploitation potentiality. Based on field water testing, water level monitoring, pumping test, as well as indoor leaching experiment, applying mathematical statistics, Pipers trilinear nomograph and PHREEQC chemistry simulation methods, saline water area of the town of Sungeng Jiyang was studied. The results showed as follows: (1) Inland shallow groundwater presents “weather-evaporative” dynamic type; (2)The shallow saline water and middle-deep groundwater belonging to different flow system; (3) Because of the creeping flow and aqueous medium riched in clay, inland shallow groundwater mineralized significantly. In saline water area inland plain, the unique features of groundwater circulation result in brackish water dynamic relative stability.

For the protection of Jinan springs, based on the monitoring data of groundwater quality during dry seasons in 2013, the chemical characteristics evolution of karst water was analyzed by RockWare Aq·QA software, combined with hydrogeological conditions in jinan spring area. According to the groundwater quality standard, the present situation of karst water was evaluated. On the basis of the F value of evaluation, the groundwater quality zone is partitioned by ArcGIS software. The results show that: (1) the groundwater chemical types complicated from the single type (HCO3–Ca and HCO3–Ca·Mg) in 1950s to some new types (HCO3·SO4-Ca,Cl·HCO3-Ca and Cl·SO4-Ca); (2) karst water chemical environment has changed, so that karst erosion rate accelerated; (3) the groundwater quality partition shows most of this area is good water, only part of this area is IV,V type water (poor water). Research suggests Jinan karst water quality has been deteriorating.

Groundwater source pumps are popular recently in worldwide. More and more pumps have been built in city. It is well known that the heat recharged to ground aquifer from refrigeration and air-conditioning in summer will migrate along with groundwater flow. So it is worthy to study the problem such as whether it impact on the safety of oil station. This paper presents a model which use simulation the heat of groundwater pump migrate process to study the impact on oil station downstream. Through simulation the heat field diffusion procedure and temperature change are obtained. Results show that the recharged heat issued from summer groundwater source pump will spread for a long distance to oil-station with downstream flow, the temperature around oil-station rise significant. The heat may influence the safety of storage tank and oil station.

In this paper, through analyzing the generating mechanism of automobile steering resisting torque, we build MATLAB/SIMULINK torque simulation model and get the steering resisting torque under different working conditions. And the results show that the model has a higher accuracy through comparing it with actual measured steering resisting torque. Design and set up the experiment platform composed of three parts including steering system, control system and torque loading device. Based on the data of steering resisting torque obtained from the model simulation, we manipulate torque loading device to input a certain of resistance for steering system ,thus to realize accurate simulation of various steering condition on test platform ,which has paved the way for the development and debugging of EPS controller.

Nowadays,artificial recognition is widely used in the mushroom inspection system, however, it depends on subjective judgment of inspectors.Therefore,the testing personnel's experience, technology and other factors will affect the objectivity and accuracy of test results.Commodity inspection system need a high-speed, objective and accurate method for the on-line hair detection in the mushroom.On the basis of summary of domestic and foreign research, this paper studies the target identification and feature extraction techniques based on computer vision, conducts a feasibility study for the real-time hair detection system.

The main content of this paper is based on the estimate of LWH(length width and height) dimensions of a machine vision moving vehicle. The information of a vehicle’s length width and height is an important parameter to monitor Road. To achieve non-contact rapid detection of the parameter of a moving vehicle’s size, can effectively improve the efficiency of the road monitoring and provide effective technical means for China's road transport management department. First get the vehicle in sequences image and extract the vehicle from background. Then, we transform the two-dimensional image to three-dimensional image with a simple projection model for getting the parameters of the length, width and height of the vehicle. Experiments show that the accuracy of the test results of this algorithm is relatively high.

In this paper, based on the principle of induction heating and eddy current fields working, the equivalent circuit model of induction cooker heating was proposed and analyzed. By using the finite element numerical analysis software, the optimization design and model simulations of induction cooker were implemented. Finally, a new design of induction cooker with the uniform heating-coil was proposed, and the magnetic circuit modeling and simulation of new type induction cooker heating was carried out, the eddy current loss density distribution in the common wire coil and the improved wire coil was separately calculated and compared. The results shown the new wire coil had higher energy efficiency and more uniform heating characteristics, which provided a reference for the future optimization design and development of induction cooker.

The paper makes an analysis on the working device of loader, which plays an important role in the performance and economic benefit of the overall unit. The paper tries to develop the mathematical model of a loader working device, apply complex method taking the maximum breakout force of cylinder of rotating bucket as well as maximum lifting force of boom cylinder as the objective function and finally realize the optimization design of its design based on MATLAB software, probing into finding a efficient solution for the technical problems existing in the working device design and manufacturing.

Aiming at avoiding misregistration in complicated medical image registration based on SURF (Speed-Up Robust Features)-TPS (Thin-Plate Spline), we propose a novel algorithm. This method is based on SURF and human interaction method for feature extraction. Then we improve SURF-TPS and propose an algorithm named TPS-SEMISURF which obtains the deformation field by calculating the Thin-plate spline of the feature points, and finally does the medical image non-rigid registration according to the parameters. Experimental results showed that the proposed method can register medical images effectively. It has a good robustness and owns better precision and rate than traditional algorithm.

Traditional medical image enhancement method has some disadvantages. They can not significantly improve the medical image edge, texture and detailed information. Besides the enhancement effect is susceptible to interference noise information. This paper proposed enhancement algorithms combining bidimensional empirical mode decomposition and the wavelet edge enhancement method. The first step is using the method of bidimensional empirical mode decomposition to process medical image, achieve image information with different frequency. And then our method using wavelet transform to enhance different frequency image edge, texture information. Through the comparison of proposed method with the existing method, it has been verified the proposed method has a better effect in the detail enhancement of medical images.

The effect of T6 heat treatment on dry sliding friction and wear characteristics of Al-20Si-5Cu under a fixed sliding speed of 200r/min and sliding time of 30mins was illustrated in this paper. The result reveals that T6 heat treatment can improve morphology of primary Si and Al2Cu particles, enhance the hardness of the matrix. Wear rate increased with increasing of applied load. T6 heat treated samples have high wear resistance which is related to the improvement of microstructure, particularly with their increased hardness of matrix. But friction coefficient varies with heat treatment processes and has no sensitivity to applied loads, which fluctuates in a small range, so the friction coefficient can be considered to be stable. The wear mechanisms of T6 heat treated samples are also changed with increasing of applied load, from oxidative wear to fatigue wear.

Collaborative filtering is regarded as the most prevailing techniques for recommendation system. Slope one is a family of algorithms used for collaborative filtering. It is the simplest form of non-trivial item-based collaborative filtering based on ratings. But all the family of use CF algorithms ignores one important problem: ratings produced at different times are weighted equally. It means that they cant catch users different attitudes at different time. So in this paper, we present a new algorithm, which could assign different weights for items at different time. Finally, we experimentally evaluate our approach and compare it to the original Slope One. The experiment shows that the new slope one algorithms can improve the precision

CPU uses STM32F103RBT6 as core human thermal infrared sensors, ultrasonic sensors and temperature sensors as detection systems, motion control module as the power system, real-time monitoring and control system. A wireless data communication system and wireless audio and video transmission system as robot "ears" and "eyes", so that a robot is capable of all-round, three-dimensional "feel" the environment, man-to make accurate judgments and control.

Currently,along with the rapid development of search engine and it towards the direction of the commercialization step by step, special search engine technology arises at the historic moment.In this article, according to the principlemodel and indexers of search engine tool of Lucene, we design a search engine system. In this system, a user can input a text in front of home page of this website, the system will use Ajax technology to match the search content automatically.And then it will show search results in the form list below the drop-down. At the same time we can click search, it will highlight the search content and display in jsp page. Actually,it has absoultely meaning in realistic.

Orthogonal Frequency Division Multiplexing(OFDM) is going to become the most important technique in the future communication system. The paper presents the principle of OFDM,establishes a simulation model of OFDM communication system based on simulink.By utilizing the system,we briefly analyse the simulation results and conclude the the performance characteristics of OFDM system.

The small-signal stability problem of complex connected DC DPS was studied. Using mathematical induction method, it is proved that the N subsystems cascaded DPS can be seemed as two equivalent subsystems at arbitrary interface as the stability conclusion is the same. But for complex connected DPS which have M sources, it could be equivalent to M sources and one load system instead of two equivalent subsystems and M minor loop gain at M different interfaces should be satisfied Nyquist criterion simultaneously to ensure the DPS's stability.

The influence of temperature on the dry sliding wear behavior of as-cast SiCp/A356 composite under 150r/min, 6N and 30 min has been illustrated in this paper. The results reveal that the wear rate is very sensitive to the change of temperature and it exhibits lower wear rate at the range from 100°C to 200°C. However, the wear rate increases linearly due to adhesive wear operating a long duration at 250°C. The friction stability decreases sharply with the temperature raising. Formation of continuous grooves and some damaged regions are presented on the worn surfaces of the samples at lower and intermediate temperature. Parallel lips (wave like material flow) along the sliding direction are observed at higher temperature of the sample. The wear mechanisms involve an initial oxidative wear regime and spalling wear regime for a long duration and followed by an adhesive wear regime as the temperature raising.

The fusion protein MG7-scFv/SEB has shown anti-tumor activity on gastric cancer in vitro and in vivo. Tumor necrosis factor-alpha (TNF-α) is a cytokine exerting anti-tumor effectiveness in various models and modes of applications. In this study, we explored the combination effects of MG7-scFv/SEB and TNF-α in experimental gastric cancer. Both MG7-scFv/SEB and TNF-α could effectively result in a significant inhibition of tumor growth in our experimental models when administered alone. What’s more, MG7-scFv/SEB synergized with TNF-α in further reducing the growth of gastric tumors in gastric-tumor-bearing rats as compared to mono therapy. Additionally, the survival rate of gastric-tumorbearing rats administrated with combined therapy was significantly higher than that of rats treated with MG7-scFv/SEB or TNF-α. These results indicate that combined therapy with MG7-scFv/SEB and TNF-α is a promising strategy for human cancer therapy.

The consensus problems of two situations for singular multi-agent systems with fixed topology are discussed: directed graph without spanning tree and the disconnected undirected graph. A sufficient and necessary condition is obtained by applying the stability theory and the system is reachable asymptotically. But for normal systems, this can’t occur in upper two situations. Finally a simulation example is provided to verify the effectiveness of our theoretical result.

This paper presents a modular experimental animation for experimental course for the analog electronic technology, which is an important means to improve the students' theory and practice. The design includes five modules: experimental purpose,instrument,principle,content and reports.Every module display corresponding content in the form of animation, and modular experimental animation show good interaction and strong operability. Animation design of the experiment has been successfully applied in the Shandong University at Weihai for several years and gets the recognition from the school leaders, teachers and students.

Consensus of singular multi-agent systems is studied, where the dynamics of each agent is described by a continuous-time singular system. Based on the controllability theory of singular systems, the consensus problem under consideration is transformed into the stability problem of a low-order normal system. Moreover, a sufficient and necessary condition for consensus is obtained by applying the stability theory. Finally, simulation examples are provided to validate the theoretical results.